CN108743899A - Draft bacteriostatic agent and preparation method thereof - Google Patents

Draft bacteriostatic agent and preparation method thereof Download PDF

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Publication number
CN108743899A
CN108743899A CN201810906573.9A CN201810906573A CN108743899A CN 108743899 A CN108743899 A CN 108743899A CN 201810906573 A CN201810906573 A CN 201810906573A CN 108743899 A CN108743899 A CN 108743899A
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parts
bacteriostatic agent
draft
agent according
cortex
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CN108743899B (en
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杨永胜
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GUANGZHOU SAIMEI PHARMACEUTICAL Co.,Ltd.
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Can Tai Holdings (fujian) Ltd
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
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    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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Abstract

A kind of draft bacteriostatic agent includes by weight:1-2 parts of safflower;6-12 parts of caulis piperis futokadsurae;3-6 parts of jujube;3-5 parts of Cortex Ampelopsis Aconitifoliae Radicis;3-10 parts of rhizoma zingiberis;5-10 parts of Fructus Liquidambaris;6-12 parts of Semen Cuscutae;9-30 parts of Radix Codonopsis;6-12 parts of Radix Angelicae Sinensis;3-9 parts of rhizome of chuanxiong;10-15 parts of pepper root;3-5 parts of Cortex Eucommiae;3-5 parts of frankincense;15-30 parts of centella;5-9 parts of kuh-seng;3-5 parts of myrrh;9-15 parts of Caulis Spatholobi;5-15 parts of matrimony vine.Draft antibacterial liquid of the present invention can be used for treating skin disease, use it for Lesional Skin surface, both the eupnea of skin will not have been interfered to be metabolized, contained drug in liquid can again be conveyed to rapidly subcutaneously into lesions position, foot fungi and microorganism can quickly be killed, curative effect is fast, and drug availability is high.

Description

Draft bacteriostatic agent and preparation method thereof
Technical field
The present invention relates to technique in skin care fields more particularly to a kind of draft bacteriostatic agent and preparation method thereof.
Background technology
Skin disease type is various, the cause of disease is complicated, and the pathogenesis of multiple dermatosis is still less clear so far, and illness is obstinate difficult More, these skin diseases have following common pathology:1) secondary skin inflammation on the basis of sebum secretion object overflows more, Change with chemical composition since sebum secretion increases, skin surface normal flora mass propagation made to become opportunistic pathogen, Skin is invaded to be formed;2) sweat gland is unsmooth, and skin is unable to eupnea, and subcutaneous excessive moisture is unable to normal secretions and excretion is formed. In the treatment mostly based on the processing of single disease, such as eczema, heat-rash, seborrhea, pruitus, tinea pedis pass these skin diseases The therapy of system is to take orally symptomatic drugs and in the various treatment paste of Lesional Skin surface smear.The base fat of paste is oil and water What emulsification was formed, all contain lubricant component, and dermopathic unified symptom is then that sweat gland is unsmooth, bacterium, which is invaded, oozes skin, in The theory of doctor's " not general rule pain ", lubricant component contained in paste can aggravate the blocking of sweat gland of skin, be formed and sealed in skin surface It closes, as a result causes to be difficult to reach expected effect containing " effective drug again " even if in lotion, influence treatment results.
China Patent Publication No.:CN107041914A discloses a kind of for the plant antibacterial liquid of skin and its preparation side Method, it belongs to hygiene article sector.Skin degerming is compared with sterilization, part bacterial spore, filterable virus, pulmonary tuberculosis bacterium and true Bacterium etc. has the opportunity to fail to eliminate.The present invention mainly form its parts by weight be respectively 40~50 parts the tuber of multiflower knotweed, 50~60 parts Wild chrysanthemum, 50~60 parts of Radix zanthoxyli, 55~65 parts of carpet bugle, 55~65 parts of folium artemisiae argyi, 85~95 parts of the achene of Siberian cocklebur, 85~ 95 parts of borneol, 115~125 parts of amur ampelopsis root, 115~125 parts of beggar-ticks, 490~510 parts of dodecyl sulphate Sodium, 10000 parts of pure water.It can be seen that the antibacterial liquid has the following problems:
First, the tuber of multiflower knotweed can not be applied to 14 years old or less children and use, and no the tuber of multiflower knotweed of system does not contain severe toxicity, easily to user's body Body impacts.
Second, the Radix zanthoxyli easily causes poisoning using excessive.
Third, the lauryl sodium sulfate have irritation and toxicity.
4th, the bacteriostatic agent needs to use a large amount of water, causes to waste to water resource.
Invention content
For this purpose, the present invention provides a kind of draft bacteriostatic agent, to overcome bacteriostatic agent influence patient skin table in the prior art The problem of skin.
On the one hand, the present invention provides a kind of draft bacteriostatic agent, includes by weight:1-2 parts of safflower;Caulis piperis futokadsurae 6-12 Part;3-6 parts of jujube;3-5 parts of Cortex Ampelopsis Aconitifoliae Radicis;3-10 parts of rhizoma zingiberis;5-10 parts of Fructus Liquidambaris;6-12 parts of Semen Cuscutae;9-30 parts of Radix Codonopsis;Radix Angelicae Sinensis 6-12 parts;3-9 parts of rhizome of chuanxiong;10-15 parts of pepper root;3-5 parts of Cortex Eucommiae;3-5 parts of frankincense;15-30 parts of centella;5-9 parts of kuh-seng;Not yet 3-5 parts of medicine;9-15 parts of Caulis Spatholobi;5-15 parts of matrimony vine.
Preferably, the draft bacteriostatic agent includes by weight:1 part of safflower;6 parts of caulis piperis futokadsurae;3 parts of jujube;Cortex Ampelopsis Aconitifoliae Radicis 3 Part;3 parts of rhizoma zingiberis;5 parts of Fructus Liquidambaris;6 parts of Semen Cuscutae;9 parts of Radix Codonopsis;6 parts of Radix Angelicae Sinensis;3 parts of rhizome of chuanxiong;10 parts of pepper root;3 parts of Cortex Eucommiae;Breast It is 3 parts fragrant;15 parts of centella;5 parts of kuh-seng;3 parts of myrrh;9 parts of Caulis Spatholobi;5 parts of matrimony vine.
Preferably, the draft bacteriostatic agent includes by weight:2 parts of safflower;12 parts of caulis piperis futokadsurae;6 parts of jujube;Cortex Ampelopsis Aconitifoliae Radicis 5 Part;10 parts of rhizoma zingiberis;10 parts of Fructus Liquidambaris;12 parts of Semen Cuscutae;30 parts of Radix Codonopsis;12 parts of Radix Angelicae Sinensis;9 parts of rhizome of chuanxiong;15 parts of pepper root;Cortex Eucommiae 5 Part;5 parts of frankincense;30 parts of centella;9 parts of kuh-seng;5 parts of myrrh;15 parts of Caulis Spatholobi;15 parts of matrimony vine.
Preferably, the draft bacteriostatic agent includes by weight:1 part of safflower;9 parts of caulis piperis futokadsurae;5 parts of jujube;Cortex Ampelopsis Aconitifoliae Radicis 4 Part;6 parts of rhizoma zingiberis;8 parts of Fructus Liquidambaris;9 parts of Semen Cuscutae;20 parts of Radix Codonopsis;8 parts of Radix Angelicae Sinensis;7 parts of rhizome of chuanxiong;12 parts of pepper root;4 parts of Cortex Eucommiae;Breast It is 4 parts fragrant;25 parts of centella;7 parts of kuh-seng;4 parts of myrrh;12 parts of Caulis Spatholobi;10 parts of matrimony vine.
On the other hand, the present invention provides a kind of production method of the draft bacteriostatic agent, including:
Step 1, the material is removed into epidermis impurity respectively, it is dry after cleaning;
Step 2, safflower, jujube, Cortex Ampelopsis Aconitifoliae Radicis and the Cortex Eucommiae in the step 1 are sequentially placed into white wine and are decocted, decocted The dregs of a decoction are filtered out after boiling, and obtain admixing medical solutions;
Step 3, by caulis piperis futokadsurae in the step 1, Fructus Liquidambaris, Semen Cuscutae, Radix Codonopsis, rhizome of chuanxiong, pepper root, frankincense, centella, Myrrh and Caulis Spatholobi chopping, mixing, and mashed, the mixture is filtered after mashing, filters out the dregs of a decoction, liquid is mixed It is bonded in the admixing medical solutions in the step 1;
Step 4, the rhizoma zingiberis, Radix Angelicae Sinensis, kuh-seng, matrimony vine are shredded and is added in ethyl alcohol, stirred and heated, mixed Liquid will stir in mixed liquor that gained admixing medical solutions are added in the step 3 and at the uniform velocity, up to the grass after being cooled to room temperature This bacteriostatic agent.
Further, it is 65-80 DEG C that temperature is decocted in the step 2, decocting time 2h.
Further, the whipping process in the step 3 can be manpower stirring or mechanical agitation.
Further, the fineness after step 3 Chinese medicine is mashed is 100 mesh.
Further, water or ethyl alcohol is added during the mashing of the step 3 in medicinal material mixture.
Further, the temperature in the step 4 is 60-85 DEG C, mixing speed 60rpm.
Compared with prior art, the beneficial effects of the present invention are draft antibacterial liquid of the present invention can be used for treating Skin disease uses it for Lesional Skin surface, will not only interfere the eupnea of skin to be metabolized, but also can make contained drug in liquid Rapid be conveyed to subcutaneously enters lesions position, can quickly kill fungi and microorganism, and curative effect is fast, and drug availability is high.
Further, each component effect is as follows in the present invention:
Safflower:Alias red blue flower, thorn safflower, composite family, safflower plant, dry tubular flower is orange red, and floral tube is narrow thin, Apex 5 is split, sliver narrow line shape, and anther yellow is unified into pipe, is higher by except sliver, and there is column cap exposing in center;Tool is special fragrant Gas, mildly bitter flavor;The flower of safflower is used as medicine, can be with invigorate blood circulation, and stasis eliminatings analgesic, controlling through closing, abdominal mass, difficult labour, stillborn foetus, lochia is not Row, hemostasis are had a pain, carbuncle swells, injury from falling down.
Caulis piperis futokadsurae:For the drying rattan of Piperaceae plant wind rattan;Acrid flavour, hardship, slightly warm in nature;For wind-cold-dampness arthralgia, podomere pain Bitterly, muscle arteries and veins contraction, joint stuffiness.
Jujube:For the ripening fruits of Rhamnaceae plant jujube;Major function is tonifying spleen and stomach, and nourishing generate fluid adjusts battalion to defend, antidote Poison controls stomach void deficiency of food, and the weak loose stool of spleen, qi-blood-body fluid is insufficient, disharmony between ying and wei, palpitation and severe palpitation, and married woman's stolen goods are hot-tempered.
Cortex Ampelopsis Aconitifoliae Radicis:For the root skin of vitaceae ampelopsis aconitifolia;Major function is:Promoting blood circulation to remove blood stasis, eliminating inflammation and expelling toxin are raw Flesh long bone, eliminate wind and clear damp control traumatic injury, fracture, boil swelling and pain, rheumatic arthritis.
Rhizoma zingiberis:In flat bulk, have finger-like branch, surface lark or grayish brown, coarse, tool vertical wrinkle and apparent Link, bifurcation often have that scale leaf is remaining, and there are stem trace or bud in branch top, and matter is solid, section yellow-white or canescence, mealiness or Graininess, endodermis ring grain is apparent, and vascular bundle and yellow oil drop are dispersed in.Gas is fragrant, special, and acrid flavour is peppery.
Fructus Liquidambaris:For collective fruits, formed by most small capsule set, spherical in shape, 2~3cm of diameter, base portion has total carpopodium, Surface taupe brown or sepia, have most spines and the small blunt thorn of beak, long 0.5~1mm often to fracture, and cracking at the top of small capsule is in Cellular aperture, body is light, and matter is hard, is not easy to break;Gas is micro-, lightly seasoned, and bitter is mild-natured;For joint pain, numb spasm, oedema Turgor, breast is few, Amenorrhea.
Semen Cuscutae:For convolvulaceous plant Cuscuta australis or the dry mature seed of Semen Cuscutae;With tonifying the liver and kidney, controlling nocturnal emission with astringent drugs The effect of contracting urine, tocolysis, improving eyesight, antidiarrheal, external application have the effect of disappearing wind nti-freckle, are usually used in kidney deficiency and liver, soreness and weakness of waist and knees, impotence Seminal emission, enuresis frequent micturition, vaginal bleeding due to deficiency of the kidney during pregnancy, fetal irritability, blurred vision tinnitus, spleen kidney deficiency are rushed down, externally treating leucoderma.
Radix Codonopsis:Radix Codonopsis is sweet in flavor, mild-natured;There is tonifying middle-Jiao and Qi, quench the thirst, strengthening spleen and tonifying lung, nourishes blood and promotes the production of body fluid, for spleen-lung Qi deficiency, food Few burnout, false asthma cough, insufficiency of vital energy and blood, sallow complexion, palpitation, injury thirst, Heat Diabetes;Lack of desire to speak and qi, four limbs without Power is off one's feed, the diseases such as the deficiency of vital energy, deficiency of qi and fluid, deficiency of qi and blood and blood deficiency chlorosis.
Radix Angelicae Sinensis:For the dry root of umbelliferae angelica.Main product the southeast of Gansu, it is more with Minxian County yield, it is high-quality, secondly It is cultivation for provinces such as Yunnan, Sichuan, Shaanxi, Hubei;With replenishing and activating blood, menstruction regulating and pain relieving, the effect of relaxing bowel;It is common In blood deficiency chlorosis, dizziness palpitaition, irregular menstruation, closed dysmenorrhea, asthenia cold abdominalgia, arthralgia pain due to rheumatism, injury from falling down, ulcer sores, intestines Dry constipation.It is sweet in flavor, pungent, it is warm-natured.
Rhizome of chuanxiong:For irregular nodular pattern fist shape agglomerate, diameter 2-7cm;Surface yellowish-brown, coarse shrinkage have most parallel There is the similar round stem trace of recess on the wheel section of protuberance, top, has most small warty root traces on downside and wheel section;Matter is solid, not easy to break Disconnected, section yellow-white or lark dissipate the grease chamber for having yellowish-brown, and forming layer is in wavy ring grain gas giving off a strong fragrance, bitter, pungent, slightly numb Tongue sense, micro- Hui Tian;Can be used for stagnation of QI and blood pain to demonstrate,prove, pungent scattered temperature is logical, can promoting blood circulation and removing blood stasis and promoting qi circulation and relieving pain, have a headache, rheumatism numbness Bitterly, pungent-warm, which rises, dissipates, can " the uplink head ", wind-expelling pain-stopping, to control headache key medicine, no matter chill, wind-heat, rheumatism, the deficiency of blood, blood stasis head Pain can use it with card compatibility.
Pepper root:Alias root of Lindera glauca (Sieb. Et Zucc.) Blume, ox tendon strip root, Thunder God are high;Red autumnal leaves bavin, gold toothed oak (Anhui), acrid flavour, hardship are warm-natured; Cure mainly arthralgia pain due to rheumatism, traumatic injury, gastral cavity pain, de-power internal lesion caused by overexertion, bronchitis, oedema, external application controls sore swell and ache curative, and extreme misery scalds Wound.
Cortex Eucommiae:For the bark of Eucommiaceae plant Cortex Eucommiae, filling liver kidney, strengthening the bones and muscles, tocolysis;It is sweet micro- acrid in flavour and warm in nature;Cure mainly spinal column acid Pain, foot and knee flaccidity, dribbling urination, uncontrolled urination, threatened abortion are intended to fall, fetal irritability, hypertension.
Frankincense:The resin oozed out for olive subject plant Boswellia carterii and congener bark;It is pungent, bitter, temperature;For the obstruction of qi in the chest heart Bitterly, gastral cavity pain, dysmenorrhoea Amenorrhea, postpartum stasis, abdominal mass abdominal pain, arthralgia pain due to rheumatism, muscle arteries and veins contraction, traumatic injury, carbuncle swells sore.
Centella:Centella, Chinese medicine name are the drying herb of samphire centella;It is bitter, pungent, it is cold in nature;With clear Hot dampness removing, the efficacy of removing toxicity for detumescence effect, is usually used in jaundice with damp-heat pathogen, heatstroke diarrhea, urolithiasis blood strangury, carbuncle sore tumefacting virus, injury from falling down.
Kuh-seng:For the dry root of legume kuh-seng;It is bitter, trembles with fear;There are heat-clearing and damp-drying drug, desinsection, the work(of diuresis, for heat Dysentery is had blood in stool, jaundice renal shutdown, leukorrhea with reddish discharge, swelling of vulva pruritus vulvae, eczema, wet sore, pruitus, and mange leprosy controls trichomonas vagina outside It is scorching.
Myrrh:For olive subject plant Chinese violet tree or the dry resin of Ha Didingshu;Acrid flavour, hardship, it is mild-natured;For the obstruction of qi in the chest heart Bitterly, gastral cavity pain, dysmenorrhoea Amenorrhea, postpartum stasis , Disorder lump in the abdomen is suffered from abdominal pain, arthralgia pain due to rheumatism, traumatic injury, the illnesss such as carbuncle swells sore are controlled It treats.
Caulis Spatholobi:For the drying rattan of legume spatholobus suberectus;Bitter, sweet, warm;For irregular menstruation, dysmenorrhoea, Amenorrhea, wind Arthritis with fixed pain caused by dampness pain, paralysis and numbness, blood deficiency chlorosis.
Matrimony vine:Matrimony vine, the also known as fruit of Chinese wolfberry, red ear pendant are that maturation of Solanaceae undershrub matrimony vine is real;Sweet and neutral;Cure mainly liver kidney Deficiency, the vertigo of blood and essence asthenia, hypopsia, the soreness and weakness of waist and knees of the deficiency of liver-yin and kidney-yin, seminal emission, the deficiency of Yin are quenched one's thirst.
Specific implementation mode
In order to make objects and advantages of the present invention be more clearly understood, the present invention is further retouched with reference to embodiment It states;It should be appreciated that specific embodiment described herein is used only for explaining the present invention, it is not intended to limit the present invention.
The embodiment of the present invention is with safflower, caulis piperis futokadsurae, jujube, Cortex Ampelopsis Aconitifoliae Radicis, rhizoma zingiberis, Fructus Liquidambaris, Semen Cuscutae, Radix Codonopsis, Radix Angelicae Sinensis, river Vault, pepper root, Cortex Eucommiae, frankincense, centella, kuh-seng, myrrh, Caulis Spatholobi and matrimony vine are raw material, not below according to each embodiment Same proportioning illustrates.
Embodiment 1
A kind of draft bacteriostatic agent, production method are:
Step 1, the material is removed into epidermis impurity respectively, it is dry after cleaning;
Step 2,3 parts of 1 part of the safflower, 3 parts of jujube, 3 parts of Cortex Ampelopsis Aconitifoliae Radicis and Cortex Eucommiae are sequentially placed into white wine and are decocted, It is 65 DEG C to build temperature, filters out the dregs of a decoction after decocting 2h, obtains admixing medical solutions;
Step 3, by 6 parts of the caulis piperis futokadsurae, 5 parts of Fructus Liquidambaris, 6 parts of Semen Cuscutae, 9 parts of Radix Codonopsis, 3 parts of rhizome of chuanxiong, 10 parts of pepper root, 9 parts of 3 parts of frankincense, 15 parts of centella, 3 parts of myrrh and Caulis Spatholobi shred and are added and mixed into pure water, and are mashed to fineness For 100 mesh, the mixture is filtered after mashing, filters out the dregs of a decoction, liquid is mixed to the admixing medical solutions in the step 1 In;
Step 4,3 parts of the rhizoma zingiberis, 6 parts of Radix Angelicae Sinensis, 5 parts of kuh-seng, 5 parts of matrimony vine are shredded and is added in ethyl alcohol, stirring is simultaneously 60 DEG C are heated to, mixed liquor is obtained, gained admixing medical solutions are added in the mixed liquor in the step 3 and with 60rpm at the uniform velocity Stirring, up to the draft bacteriostatic agent A after being cooled to room temperature.
Embodiment 2
A kind of draft bacteriostatic agent, production method are:
Step 1, the material is removed into epidermis impurity respectively, it is dry after cleaning;
Step 2,5 parts of 2 parts of the safflower, 6 parts of jujube, 5 parts of Cortex Ampelopsis Aconitifoliae Radicis and Cortex Eucommiae are sequentially placed into white wine and are decocted, It is 80 DEG C to build temperature, filters out the dregs of a decoction after decocting 2h, obtains admixing medical solutions;
Step 3, by 12 parts of the caulis piperis futokadsurae, 10 parts of Fructus Liquidambaris, 12 parts of Semen Cuscutae, 30 parts of Radix Codonopsis, 9 parts of rhizome of chuanxiong, pepper root 15 parts of 15 parts, 5 parts of frankincense, 30 parts of centella, 5 parts of myrrh and Caulis Spatholobi shred and are added and mixed into pure water, and are mashed It is 100 mesh to fineness, the mixture is filtered after mashing, filters out the dregs of a decoction, liquid is mixed mixed into the step 1 It closes in liquid;
Step 4,10 parts of the rhizoma zingiberis, 12 parts of Radix Angelicae Sinensis, 9 parts of kuh-seng, 15 parts of matrimony vine are shredded and is added in ethyl alcohol, stirred And 85 DEG C are heated to, mixed liquor is obtained, gained admixing medical solutions are added in the mixed liquor in the step 3 and even with 60rpm Speed stirring, up to the draft bacteriostatic agent B after being cooled to room temperature.
Embodiment 3
A kind of draft bacteriostatic agent, production method are:
Step 1, the material is removed into epidermis impurity respectively, it is dry after cleaning;
Step 2,5 parts of 2 parts of the safflower, 6 parts of jujube, 5 parts of Cortex Ampelopsis Aconitifoliae Radicis and Cortex Eucommiae are sequentially placed into white wine and are decocted, It is 74 DEG C to build temperature, filters out the dregs of a decoction after decocting 2h, obtains admixing medical solutions;
Step 3, by 12 parts of the caulis piperis futokadsurae, 10 parts of Fructus Liquidambaris, 12 parts of Semen Cuscutae, 9 parts of Radix Codonopsis, 9 parts of rhizome of chuanxiong, pepper root 15 15 parts of part, 5 parts of frankincense, 30 parts of centella, 5 parts of myrrh and Caulis Spatholobi shred and are added and mixed into pure water, and mashed to Fineness is 100 mesh, is filtered to the mixture after mashing, filters out the dregs of a decoction, liquid is mixed to the mixing in the step 1 In liquid;
Step 4,10 parts of the rhizoma zingiberis, 12 parts of Radix Angelicae Sinensis, 9 parts of kuh-seng, 15 parts of matrimony vine are shredded and is added in ethyl alcohol, stirred And 75 DEG C are heated to, mixed liquor is obtained, gained admixing medical solutions are added in the mixed liquor in the step 3 and even with 60rpm Speed stirring, up to the draft bacteriostatic agent C after being cooled to room temperature.
It is real that sterilizing is carried out to staphylococcus aureus, streptococcus and corynebacterium diphtheriae respectively using above-mentioned three kinds of bacteriostatic agents It tests, experimental method is:
A concentration of 100CFU/mL bacterium solutions are made using conventional method, each bacterium solution are divided into three parts, every part of 10ml, film On the glass sheet, and on each sheet glass above-mentioned three kinds of draft bacteriostatic agent 5mL is added dropwise, stands 10min, measures each bacterium solution bacterium solution afterwards Concentration, test result are as shown in table 1:
The bacteriostatic experiment table of 1 draft bacteriostatic agent of table
It can be obtained according to table 1, draft bacteriostatic agent of the present invention has above-mentioned bacterium very excellent fungistatic effect, bacteriostasis rate Up to 90%.
The foregoing is merely the preferred embodiment of the present invention, are not intended to restrict the invention;For those skilled in the art For member, the invention may be variously modified and varied.Any modification made by all within the spirits and principles of the present invention, Equivalent replacement, improvement etc., should all be included in the protection scope of the present invention.

Claims (10)

1. a kind of draft bacteriostatic agent, which is characterized in that include by weight:
2. draft bacteriostatic agent according to claim 1, which is characterized in that include by weight:1 part of safflower;Caulis piperis futokadsurae 6 Part;3 parts of jujube;3 parts of Cortex Ampelopsis Aconitifoliae Radicis;3 parts of rhizoma zingiberis;5 parts of Fructus Liquidambaris;6 parts of Semen Cuscutae;9 parts of Radix Codonopsis;6 parts of Radix Angelicae Sinensis;3 parts of rhizome of chuanxiong;Pepper 10 parts of root;3 parts of Cortex Eucommiae;3 parts of frankincense;15 parts of centella;5 parts of kuh-seng;3 parts of myrrh;9 parts of Caulis Spatholobi;5 parts of matrimony vine.
3. draft bacteriostatic agent according to claim 1, which is characterized in that include by weight:2 parts of safflower;Caulis piperis futokadsurae 12 Part;6 parts of jujube;5 parts of Cortex Ampelopsis Aconitifoliae Radicis;10 parts of rhizoma zingiberis;10 parts of Fructus Liquidambaris;12 parts of Semen Cuscutae;30 parts of Radix Codonopsis;12 parts of Radix Angelicae Sinensis;Rhizome of chuanxiong 9 Part;15 parts of pepper root;5 parts of Cortex Eucommiae;5 parts of frankincense;30 parts of centella;9 parts of kuh-seng;5 parts of myrrh;15 parts of Caulis Spatholobi;15 parts of matrimony vine.
4. draft bacteriostatic agent according to claim 1, which is characterized in that include by weight:1 part of safflower;Caulis piperis futokadsurae 9 Part;5 parts of jujube;4 parts of Cortex Ampelopsis Aconitifoliae Radicis;6 parts of rhizoma zingiberis;8 parts of Fructus Liquidambaris;9 parts of Semen Cuscutae;20 parts of Radix Codonopsis;8 parts of Radix Angelicae Sinensis;7 parts of rhizome of chuanxiong;Recklessly 12 parts of green pepper root;4 parts of Cortex Eucommiae;4 parts of frankincense;25 parts of centella;7 parts of kuh-seng;4 parts of myrrh;12 parts of Caulis Spatholobi;10 parts of matrimony vine.
5. a kind of production method of the draft bacteriostatic agent as described in any one of claim 1-4 claims, which is characterized in that packet It includes:
Step 1, the material is removed into epidermis impurity respectively, it is dry after cleaning;
Step 2, safflower, jujube, Cortex Ampelopsis Aconitifoliae Radicis and the Cortex Eucommiae in the step 1 are sequentially placed into white wine and are decocted, after decoction The dregs of a decoction are filtered out, admixing medical solutions are obtained;
Step 3, by caulis piperis futokadsurae, Fructus Liquidambaris, Semen Cuscutae, Radix Codonopsis, rhizome of chuanxiong, pepper root, frankincense, centella, myrrh in the step 1 Shredded with Caulis Spatholobi, mixing and is mashed, is filtered to the mixture after mashing, filters out the dregs of a decoction, by liquid mix to In admixing medical solutions in the step 1;
Step 4, the rhizoma zingiberis, Radix Angelicae Sinensis, kuh-seng, matrimony vine are shredded and are added in ethyl alcohol, stirred and heated, obtain mixed liquor, It will stir in mixed liquor that gained admixing medical solutions are added in the step 3 and at the uniform velocity, up to the draft after being cooled to room temperature Bacteriostatic agent.
6. the preparation method of draft bacteriostatic agent according to claim 5, which is characterized in that decoct temperature in the step 2 It is 65-80 DEG C, decocting time 2h.
7. the preparation method of draft bacteriostatic agent according to claim 5, which is characterized in that stirred in the step 3 Journey can be manpower stirring or mechanical agitation.
8. the preparation method of draft bacteriostatic agent according to claim 5, which is characterized in that step 3 Chinese medicine is smash Fineness after rotten is 100 mesh.
9. the preparation method of draft bacteriostatic agent according to claim 5, which is characterized in that the step 3 mashes process In water or ethyl alcohol are added in medicinal material mixture.
10. the preparation method of draft bacteriostatic agent according to claim 5, which is characterized in that the temperature in the step 4 is 60-85 DEG C, mixing speed 60rpm.
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Publication number Priority date Publication date Assignee Title
CN113144121A (en) * 2020-11-23 2021-07-23 江西菁美生物科技有限公司 Herbal antibacterial liquid and preparation method thereof

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CN102048927A (en) * 2011-01-13 2011-05-11 中国人民解放军第四军医大学 Chinese medical compound preparation for treating skin injury and the preparation method and application thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102048927A (en) * 2011-01-13 2011-05-11 中国人民解放军第四军医大学 Chinese medical compound preparation for treating skin injury and the preparation method and application thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113144121A (en) * 2020-11-23 2021-07-23 江西菁美生物科技有限公司 Herbal antibacterial liquid and preparation method thereof

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