CN108743623A - The concealing method of stench of animal traditional Chinese medicinal dispensing granule - Google Patents
The concealing method of stench of animal traditional Chinese medicinal dispensing granule Download PDFInfo
- Publication number
- CN108743623A CN108743623A CN201810661731.9A CN201810661731A CN108743623A CN 108743623 A CN108743623 A CN 108743623A CN 201810661731 A CN201810661731 A CN 201810661731A CN 108743623 A CN108743623 A CN 108743623A
- Authority
- CN
- China
- Prior art keywords
- animal
- granule
- parts
- chinese medicinal
- stench
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1664—Compounds of unknown constitution, e.g. material from plants or animals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Botany (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Insects & Arthropods (AREA)
- Medicinal Preparation (AREA)
Abstract
The present invention relates to a kind of concealing methods of stench of animal traditional Chinese medicinal dispensing granule, belong to animal tcm granule preparing technical field.The method includes following procedure：Animal tcm dry extract, superfine silica gel powder, pregelatinized starch, Mint Essence and lemon extract are sufficiently mixed, the pelleting of 90% ethyl alcohol is added, the animal tcm granule of no bad smell is made, wherein the parts by weight of each raw material composition are in drying：100 parts of animal tcm dry extract, 0.1-0.5 parts of superfine silica gel powder, 1-3 parts of pregelatinized starch, 0.5-2 parts of Mint Essence, 0.5-2 parts of lemon extract, 90% 15-30 parts of ethyl alcohol.The present invention can cover the stink of animal tcm granule raw meat.
Description
Technical field
The present invention relates to animal tcm granules, especially the cover side of stench of animal traditional Chinese medicinal dispensing granule
Method.Belong to animal tcm granule preparing technical field.
Background technology
Chinese medicinal granule is using the prepared slices of Chinese crude drugs as raw material, using made of the methods of extraction, low temperature concentration, dry
Granula.It is both for clinical flexible prescription, and allotment is taken after mixing it with water, but also as the raw material of industry of Chinese medicine preparation.
Animal kind medicine mainly contains the ingredients such as protein, alkaloid.The albumen point that protein is generated via microbial reproduction
Solve enzyme and decompose and generate amino acid, deamination occurs again for amino acid, decarboxylating and oxidation form intermediate product and
The small product of molecular weight, such as indoles, putrescine, tyrasamine, histamine, aliphatic acid, ultimately produce hydrogen sulfide, methane, ammonia, mercaptan etc.,
At the same time, strong foul smell can be also generated with the decomposition of aliphatic acid and sugar, especially fatty oxygenolysis, therefore, moved
Species medicinal material has unpleasant bad smell.Animal medicinal material is during Preparation process, although by the places to go portion such as wine system, vinegar
Divide bad smell, still, granule is made through water extraction, drying, still there is strong bad smell.When hospital clinical is formulated,
Strong bad smell enables patient be difficult to receive, it is difficult to take, or even vomiting phenomenon occurs, it is special to seriously affect Chinese medicinal granule
It is the clinical application of animal tcm granule.
It is a kind of that raw meat is covered using coating (tablet) after tabletting there are two types of the traditional cover bad smell method of Chinese medicine preparation is usual
Stink, encapsulated (capsule) covers bad smell after particle is made in one kind.Above two dosage form is all made of hot water and takes, drug
Not in orodispersible, stop of the bad smell in oral cavity is avoided, patient is easy to receive.And the instructions of taking of Chinese medicinal granule is
It is taken after hot water dissolving, drug first disperses in the hot water, and the bad smell of animal tcm granule discharges in water simultaneously,
When taking, bad smell cause smell, the sense of taste discomfort, it is difficult to take.Therefore, above two dosage form is not suitable for Chinese medicinal granule
Especially animal tcm granule.
The concealing method of stench of animal traditional Chinese medicinal dispensing granule has not been reported.
Invention content
The purpose of the present invention is to overcome the above shortcomings and to provide a kind of suitable for stench of animal traditional Chinese medicinal dispensing granule
Concealing method.
What the present invention was realized by the following technical scheme：A kind of cover side of stench of animal traditional Chinese medicinal dispensing granule
Method, the method includes following procedure：By animal tcm dry extract, superfine silica gel powder, pregelatinized starch, Mint Essence and lemon
Lemon essence is sufficiently mixed, and the pelleting of 90% ethyl alcohol is added, and the animal tcm granule of no bad smell is made in drying, wherein
The parts by weight of each raw material composition are：
The parts by weight of the concealing method of stench of animal traditional Chinese medicinal dispensing granule of the present invention, each raw material composition are：
Superfine silica gel powder is the anhydrous powder of light white colloidal silica gel, and odorless, tasteless has good mobility, can
So that the mobility of powder or particle is increased, medicinal powder can be made to be uniformly mixed.
Pregelatinized starch, disintegration is rapid, and good water solubility can accelerate the dissolving of particle in water.
Mint Essence, lemon extract are edible powdered essence, soluble in water, distribute pleasant fragrance, pleasure is smelt
Feel, the sense of taste, mind frankness can be made one；The smell that component unhappy (bad smell) can also be covered, is easy to receive, convenient for clothes
With.
Ethyl alcohol, on the one hand the wetting agent as granulation, on the other hand has the function of removing bad smell.
The advantage of the invention is that：
1, the invention supplementary product consumption is few, simple for process, easy to operate, and manufactured granule stability is good, dissolves in water, symbol
It closes Chinese medicinal granule water and rushes instant Medicinal Trait.
2, the Mint Essence and lemon extract that the invention uses, is food flavor, and soluble easily in water, fragrance is pleasant, can be covered
The unhappiness smell such as bad smell of lid animal tcm；Without bad smell, patient is easy to receive manufactured granule, facilitates clinic
Using.
Specific implementation mode：
Embodiment 1：
Earthworm dry extract 1000g is taken, superfine silica gel powder 3.2g, pregelatinized starch 19g, Mint Essence 7g, lemon extract are added
9g is sufficiently mixed, and adds 90% ethyl alcohol 200g, and particle is made, and the Pheretima Compounding Granules of no bad smell are made in 60 DEG C of drying.
Embodiment 2：
Ground bettle dry extract 1000g is taken, superfine silica gel powder 3.5g, pregelatinized starch 17g, Mint Essence 8g, lemonene are added
Smart 7g, is sufficiently mixed, and adds 90% ethyl alcohol 210g, and particle is made, and the ground bettle granule of no bad smell is made in 60 DEG C of drying.
Embodiment 3：
Stiff silkworm dry extract 1000g is taken, superfine silica gel powder 3.3g, pregelatinized starch 18g, Mint Essence 9g, lemon extract are added
6g is sufficiently mixed, and adds 90% ethyl alcohol 220g, and particle is made, and the stiff silkworm granule of no bad smell is made in 60 DEG C of drying.
Claims (2)
1. a kind of concealing method of stench of animal traditional Chinese medicinal dispensing granule, it is characterised in that the method is：It will be in animal class
Medicine dry extract, superfine silica gel powder, pregelatinized starch, Mint Essence and lemon extract are sufficiently mixed, and the pelleting of 90% ethyl alcohol is added,
Drying, is made the animal tcm granule of no bad smell, wherein the parts by weight of each raw material composition are：
2. a kind of concealing method of stench of animal traditional Chinese medicinal dispensing granule according to claim 1, it is characterised in that institute
The parts by weight for stating each raw material composition are：
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810661731.9A CN108743623A (en) | 2018-06-25 | 2018-06-25 | The concealing method of stench of animal traditional Chinese medicinal dispensing granule |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810661731.9A CN108743623A (en) | 2018-06-25 | 2018-06-25 | The concealing method of stench of animal traditional Chinese medicinal dispensing granule |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108743623A true CN108743623A (en) | 2018-11-06 |
Family
ID=63976837
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810661731.9A Withdrawn CN108743623A (en) | 2018-06-25 | 2018-06-25 | The concealing method of stench of animal traditional Chinese medicinal dispensing granule |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108743623A (en) |
-
2018
- 2018-06-25 CN CN201810661731.9A patent/CN108743623A/en not_active Withdrawn
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR100255887B1 (en) | Laxative composition containing lactic acid bacterium | |
| WO2021104155A1 (en) | Hydrogel tablet for dispelling effect of alcohol and protecting liver, and preparation method therefor and use thereof | |
| CN103918960A (en) | Jelly and preparation method thereof | |
| CN100584341C (en) | The concealing method of the stench flavor of animal tcm granule | |
| CN102669395A (en) | Chewing gum base, chewing gum and preparation method of chewing gum | |
| JPH04316459A (en) | Solid material containing propolis, its production and its use | |
| KR101538136B1 (en) | Attractive pill using Lleycornuta Lind and Chondrichtiyes and making method of it | |
| CN104739964B (en) | A kind of snail sobering preparation and preparation method thereof | |
| CN108743623A (en) | The concealing method of stench of animal traditional Chinese medicinal dispensing granule | |
| KR20130075919A (en) | Allium hookeri ingredient contained composition and its manufacturing method | |
| CN104799277A (en) | Chewable colla corii asini tablet and preparation method thereof | |
| CN102552247B (en) | Composition of vitamin C and preparation method thereof | |
| CN108653716A (en) | A kind of tealeaves essence drunk-sobering tablet and preparation method thereof | |
| KR20110121246A (en) | Natural functional food for anti-obesity wellbeing diet and its producing method | |
| CN101700254B (en) | Chinese medicine prescription granule flavoring agent, and preparation method and use method thereof | |
| CN104621327B (en) | One kind chews sugar and preparation method thereof for mouth | |
| CN106620673A (en) | Hydrogel for treating infant dental ulcer and preparation method of hydrogel | |
| CN107308216B (en) | Compound liquorice buccal tablet and preparation method thereof | |
| KR20040046570A (en) | Preparation of Powdered Cheonggukjang Using Onion and Garlic | |
| JP2006348049A (en) | Medicine and health food composition for promoting bloodstream by vasolidation | |
| KR101542202B1 (en) | Attractive pill using Maackia amurensis Rupr. et Maxim and making method of it | |
| KR101577253B1 (en) | Attractive pill using Hedyotis diffusa Willdenow and making method of it | |
| CN108159073A (en) | A kind of Calci-Mix | |
| KR100446147B1 (en) | The manufacturing method and composition of the health support food utilized by simaroubaceae | |
| JP2019041696A (en) | Oral composition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20181106 |