CN108715806A - Automatic cleaning equipment for cultivating tissue block needed for stem cell - Google Patents
Automatic cleaning equipment for cultivating tissue block needed for stem cell Download PDFInfo
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- CN108715806A CN108715806A CN201810581660.1A CN201810581660A CN108715806A CN 108715806 A CN108715806 A CN 108715806A CN 201810581660 A CN201810581660 A CN 201810581660A CN 108715806 A CN108715806 A CN 108715806A
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- cleaning
- fixed
- workbench
- traversing
- water drenching
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M39/00—Means for cleaning the apparatus or avoiding unwanted deposits of microorganisms
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/48—Automatic or computerized control
Abstract
The present invention relates to the automatic cleaning equipments for cultivating tissue block needed for stem cell, include a cleaning platform, a cleaning manipulation machine, several frame units for holding tissue block；Frame unit includes one to suspend the grip end seat of top end in midair for placing the suspention column, one that tissue block, netted cylindrical framework, a vertical distribution and bottom end be fixed on framework top surface and being fixed on；Cleaning platform includes one to frame up workbench, a water drenching workbench, a service sink；Cleaning manipulation machine includes one for capturing or decontroling the mechanical gripper of grip end seat, the lifting drive for driving mechanical gripper straight line elevating movement and for driving mechanical gripper to do the horizontal driving device of transverse reciprocating linear motion.Automatic cleaning equipment provided by the invention, cleaning performance is good, high degree of automation, work efficiency is high.
Description
Technical field
The present invention relates to tissue of biological cells cleaning equipment technical fields, are specifically related to for cultivating group needed for stem cell
Knit the automatic cleaning equipment of block.
Background technology
As the frequency that molecular biotechnology makes rapid progress and the technology is studied applied to human diseases is growing day by day, make
Obtain the beginning that bioscience circle now is in accurate biologic medical revolution.Such as in clinical experiment, for ease of with
The angle of molecular biosciences medicine to carry out pathological analysis to cell tissue, so need the stem cell of flood tide, cell stem cell by
Primitive cell culture obtains, therefore is the stem cell of culture flood tide, then needs mass propgation primary cell.
For the staff of laboratory research, the requirement in order to meet medical experiment obtains a large amount of primary thin
Born of the same parents then need to acquire and handle more tissue block.There is presently no the equipment dedicated for cleansing tissue block, tissue block acquisitions
Cleaning way afterwards generally by technical staff with tweezers clamp tissue block in cleaning solution back and forth shake clean, with remove
The impurity such as haemocyte.Manual cleansing tissue block, heavy workload waste time, and easily cause the fatigue of laboratory technicians, sternly
Ghost image rings the working efficiency of experiment.
Invention content
Good, high degree of automation that technical problem to be solved by the invention is to provide a kind of cleaning performances, work efficiency is high
For cultivating the automatic cleaning equipment of tissue block needed for stem cell.
In order to solve the above technical problems, the present invention provides following technical scheme：For cultivating tissue block needed for stem cell
Automatic cleaning equipment includes a cleaning platform, a cleaning manipulation machine, several frame units for being used to hold tissue block, one
PLC control cabinet；
The frame unit include one for placing tissue block, side wall be equipped with retractable switch gate netted cylindrical framework,
Suspention column that one vertical distribution and bottom end are fixed on framework top surface, one are fixed on the grip end seat for suspending top end in midair；
The cleaning platform include a genesis analysis the workbench that frames up on right side, a genesis analysis left side water drenching work
Make platform and one and is fixedly connected on the service sink to frame up between workbench front end and water drenching workbench front end；
The table surface that frames up is fixedly arranged at the front end with the fixed placement table of two cross direction profiles, shape between two fixed placement tables
Cheng Youyi cross direction profiles, for the suspention column traversing traversing gap passed through, and traversing gap width is less than grip end seat length；Work as net
When frame component is placed on two fixed placement tables, the both ends on grip end seat length direction are individually placed on two fixed placement table desktops
And suspention column is placed in traversing gap, framework is placed in below fixed placement table desktop；
It is equipped with a cleaning case for holding cleaning solution in the service sink, a top has been removably secured in the cleaning case
And the circular ring shape wash bowl that bottom end is all provided with opening, is vertically distributed, the elongated surfaces over cleaning cylinder in the traversing gap transverse center face
Central axis, the wash bowl side wall are uniformly provided with several recirculation holes, and clean in medial wall of the tube and be fixed with circular ring shape cleaning
The inner cavity of hairbrush, the circular ring shape Clean Brush for cleaning forms lifting corresponding with framework space；
It is embedded with the water drenching collecting tank of a genesis analysis on the water drenching table surface, and is additionally provided on water drenching table surface
Across the mobile placement table above water drenching collecting tank, longitudinally movable, which, which places, offers one lateral point on table desktop
Cloth, for suspending the traversing traversing placing groove passed through of column in midair, the traversing placement well width is equal with traversing gap width and traversing puts
It sets slot right end and extends to mobile placement table desktop right side, the water drenching table surface and mobile place set respectively on table desktop
There are one positioning instruction icons；Table, which is placed, when movement is moved to simultaneously fixed position of stopping when two positioning instruction icons are aligned, this
When, the traversing placing groove transverse center face and traversing gap transverse center face are in the same plane；
The cleaning manipulation machine includes one for capturing or decontroling the mechanical gripper of grip end seat, for driving mechanical gripper straight line
The lifting drive of elevating movement and for drive mechanical gripper do transverse reciprocating linear motion horizontal driving device, the machinery
Handgrip transverse reciprocating moves along a straight line and the track of straight line elevating movement is located in the elongated surfaces in traversing gap transverse center face.
It is arranged on the basis of above-mentioned technical proposal, on the service sink lateral wall and is connected with service sink inner cavity, is retractable
Maintenance door, the cleaning case bottom be fixed with a belt switch valve, with the outlet pipe that is connected of cleaning box cavity.
On the basis of above-mentioned technical proposal, be fixed on the water drenching workbench belt switch valve, with water drenching collecting tank
The drainage pipeline being connected.
On the basis of above-mentioned technical proposal, mobile four table leg bottoms for placing table are respectively and fixedly provided with movable pulley, described
On water drenching table surface be located at water drenching collecting tank at left and right sides of position at be embedded with respectively a genesis analysis, with movable pulley phase
Corresponding sliding rail, the mobile table of placing are realized with being slidably matched for corresponding sliding rail on water drenching table surface by movable pulley
Do straight skidding movement；And the rear and front end of two sliding rails corresponds to the front and back sides for extending to water drenching table surface respectively.
The present invention has an advantageous effect in that compared with prior art：Automatic cleaning equipment provided by the invention is framing up
The work being packed into tissue block to be cleaned in framework is completed on workbench, then cleans the crawl of manipulation machine and tissue block to be cleaned is housed
Frame unit movement merging service sink in carry out cleaning, after the completion of to be cleaned, cleaning manipulation machine again by the frame unit
It is mobile to be placed on progress water drenching work on water drenching workbench；Then cleaning manipulation machine repeats aforesaid operations to clean next frame unit
Interior tissue block.Cleaning performance of the present invention is good, high degree of automation, work efficiency is high.
Description of the drawings
Fig. 1 is that the present invention faces angled arrangement schematic diagram；
Fig. 2 is cleaning platform depression angle structural schematic diagram of the present invention；
Fig. 3 is service sink structural schematic diagram of the present invention；
Fig. 4 is enlarged drawing at A in Fig. 1 of the present invention；
Fig. 5 is enlarged drawing at B in Fig. 3 of the present invention；
Fig. 6 is structural schematic diagram when rinsing module of the present invention is used to rinse cleaning case inner sidewall upper portion；
Fig. 7 is structural schematic diagram when rinsing module of the present invention is used to rinse cleaning box inner wall lower part；
Figure label is：1- cleaning platforms, 11- supporting racks, 12- support plates, 121- guide rails；2- frames up workbench, 21-
Fixed placement table, the traversing gaps 22-；3- service sinks, 31- cleaning cases, 311- outlet pipes, 312- lock-bit columns, 313- lock-bit nuts,
314- card columns, 315- rotary connectors, 316- idler wheels, 32- rotary drive assemblies, 321- rotary drive motors, 322- driving wheels,
323- driven wheels, 324- rotating disks, 325- rotary shafts, 33- wash bowls, 331- recirculation holes, 34- Clean Brush for cleaning, 35- liftings are empty
Between, 36- maintenance doors, 37- cross seats, 38- accommodating chambers, 39- control room, 30- rotation holding tanks, 301- slot rollings；4- water drenching workbench,
Table, the traversing placing grooves of 421-, 422- table legs, 423- movable pulleys, 43- positioning instruction figures are placed in 41- water drenching collecting tanks, 42- movements
Mark, 44- drainage pipelines, 45- sliding rails；5- cleans manipulation machine, 51- mechanical grippers, 511- mullions, 512- grabbing claws, 513- second
Electric telescopic rod, 52- lifting drives, the first electric telescopic rods of 521-, 522- telescopic drive cylinders, 523- driving plates, 53-
Horizontal driving device, 531- lead screws, the second driving motors of 532-, 533- sliding seats, 534- guide pads；6- frame units, 61- frameworks,
62- suspends column, 63- grip end seats in midair, and 631- captures screens slot；7-PLC switch boards；8- rinsing modules, 81- fix disk, and 811- is oriented to
Slot, 82- vertical beams, 83- flushing coaming plates, 84- connecting plates, 85- third electric telescopic rods, 86- wash tub pipes, 87- Flushing nozzles,
88- guide holders；9- rack for cleaning, 91- clean fixed frame, 92- upper mounted plates, 921- through-holes, 93- bottom plates, 931- card holes.
Specific implementation mode
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to the accompanying drawings and embodiments, right
The present invention is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, and
It is not used in the restriction present invention.
In the description of the present invention, it is to be understood that, term " longitudinal direction ", " transverse direction ", "upper", "lower", "front", "rear",
The orientation or positional relationship of the instructions such as "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outside" is based on attached drawing institute
The orientation or positional relationship shown is merely for convenience of the description present invention, does not indicate or imply the indicated device or element must
There must be specific orientation, with specific azimuth configuration and operation, therefore be not considered as limiting the invention.
Include a cleaning referring to Figure 1 to Figure 7 it is found that being used to cultivate the automatic cleaning equipment of tissue block needed for stem cell
Workbench 1, one cleans manipulation machine 5, several frame units 6, a PLC control cabinet 7, a rinsing module 8 for holding tissue block.
Referring to Figures 1 and 2, the frame unit 6 includes one for placing tissue block, side wall equipped with retractable switch gate
The suspention column 62, one that vertically distribution and bottom end are fixed on 61 top surface of framework of netted cylindrical framework 61, one be fixed on suspention
The grip end seat 63 on 62 top of column.The switch gate of opening framework 61 closes upper switch door after being put into tissue block to be cleaned, completes
Tissue block to be cleaned is put into the work in frame unit 6.Framework 61 therein is netted cylindrical structure, by frame unit
After 6 are put into cleaning solution, are entered in frame unit 6 by netted shell convenient for cleaning solution and contact and clean with tissue block, needed
It is noted that the netted framework 61 belongs to the prior art, this is repeated no more.
Cleaning platform 1 include a genesis analysis the workbench 2 that frames up on right side, a genesis analysis left side water drenching
Workbench 4 and one is fixedly connected on the service sink 3 between framing up 4 front end of 2 front end of workbench and water drenching workbench.In the work that frames up
Make the work for completing to be packed into tissue block to be cleaned in framework 61 on platform 2, then cleans manipulation machine 5 and capture equipped with tissue to be cleaned
Cleaning is carried out in the movement merging service sink 3 of frame unit 6 of block, after the completion of to be cleaned, cleaning manipulation machine 5 is again by the screen frame
The movement of component 6 is placed on progress water drenching work on water drenching workbench 4；Then it is next to clean to repeat aforesaid operations for cleaning manipulation machine 5
6 inner tissue's block of frame unit.
2 table top of workbench that frames up is fixedly arranged at the front end with the fixed placement table 21 of two cross direction profiles, two fixed placements
A cross direction profiles are formed between table 21, for the traversing traversing gap 22 passed through of suspention column 62, and 22 width of traversing gap is small
In 63 length of grip end seat；When frame unit 6 is placed on two fixed placement tables 21, the both ends difference on 63 length direction of grip end seat
It is placed on two 21 desktops of fixed placement table and suspends that column 62 is placed in traversing gap 22, framework 61 is placed in 21 table of fixed placement table in midair
Below face.
The above-mentioned work that tissue block to be cleaned is put into frame unit 6 can be carried out framing up to operate on workbench 2, when
The right end in frame unit 6 from traversing gap 22 is entered after the completion of framing up and is suspended between two fixed placement tables 21；In fixation
It places and sets a crawl position label on table 21, the frame unit 6 of the leftmost side on fixed placement table 21 is pushed into the crawl position
Mark, the frame unit 6 on right side are close to the frame unit 6 in crawl position label and arrange to the right, wait in crawl successively
The frame unit 6 of position mark is cleaned the crawl of manipulation machine 5 and from after 22 left end of traversing gap removes fixed placement table 21, then will
Enter from 22 right end of traversing gap in the frame unit 6 that the workbench 2 that frames up is completed tissue block to be cleaned being put into framework 61 and hangs
It is hung between two fixed placement tables 21, and it is next to wait for push the frame unit 6 of the leftmost side at this time to move to crawl position mark
Secondary cleaned operation machine crawl.
One is equipped in the service sink 3 for holding the cleaning case 31, one of cleaning solution for driving cleaning case 31 circumferentially to revolve
The rotary drive assembly 32 turned, the cleaning case 31 are that cross section is annular, longitudinal section is isosceles trapezoid wide at the top and narrow at the bottom knot
Structure, convenient for improving stability when rotation.A top and bottom end has been removably secured in the cleaning case 31 to be all provided with opening, erect
To the circular ring shape wash bowl 33 of distribution, 33 central axis of elongated surfaces over cleaning cylinder in 22 transverse center face of the traversing gap should
33 side wall of wash bowl is uniformly provided with several recirculation holes 331, and a circular ring shape Clean Brush for cleaning is fixed on 33 madial wall of wash bowl
34, the inner cavity of the circular ring shape Clean Brush for cleaning 34 forms lifting space corresponding with framework 61 35.It is grabbed using cleaning manipulation machine 5
It takes in the merging lifting of frame unit 6 space 35 and does straight line elevating movement in the lifting space 35, meanwhile, it is driven using rotation
Component 32 drives cleaning case 31 to rotate, and is matched by elevating movement and rotary motion and realizes Clean Brush for cleaning 34 to in framework 61
The washing and cleaning operation that carries out of tissue block, cleaning performance is good.
Wherein, further include there are one cleaning fixed frame 91 in above-mentioned cleaning case 31, the cleaning fixed frame 91 includes
One annular upper mounted plate 92 corresponding with 31 inner sidewall upper portion of cleaning case and one it is opposite with 31 madial wall bottom of cleaning case
The annular bottom plate 93 answered, correspondence is fixed by socket in 33 lateral wall of wash bowl respectively for fixed plate 92, bottom plate 93
Top, bottom end are fixed into a rack for cleaning 9 to assemble.31 inner sidewall upper portion of the cleaning case corresponds at the position of upper mounted plate 92
Uniformly have it is fixed there are four lock-bit column 312, lower part corresponds at the position of bottom plate 93 it is uniformly fixed there are four card column 314, institute
State upper mounted plate 92 open up there are four run through upper and lower surface and through-hole 921 corresponding with lock-bit column 312, the bottom plate 93
It is embedded on bottom surface that there are four card holes corresponding with card column 314 931；The rack for cleaning 9 is vertically put into cleaning case 31, each card column
314 correspondences are caught in each card hole 931 of bottom plate 93, and each lock-bit column 312 corresponds to the spiral shell in the through-hole 921 of upper mounted plate 92
Line is connected with lock-bit nut 313, and so 9 lock-bit of rack for cleaning can be fixed in cleaning case 31, and wash bowl 33 is helped to fix
Position in cleaning case 31；Moreover, rack for cleaning 9 is detachably connected using aforesaid way with cleaning case 31, not only in fixed bit
When setting, lock-bit is secured, while being also convenient for dismantling rack for cleaning 9 to be rinsed 31 madial wall of cleaning case out of cleaning case 31；
Meanwhile the liquid level normality for the cleaning solution being packed into cleaning case 31 is in 92 lower section of upper mounted plate, utilizes the upper of the rack for cleaning 9
The non-porous design of fixed plate 92, reduction appear in the case where cleaning solution splashes out cleaning case 31 in cleaning process.
Moreover, 31 top surface of the cleaning case extends outward the rotary connector 315 of an annular, 3 top of the service sink
Madial wall on be embedded with rotation holding tank 30 corresponding with rotary connector 315, rotary connector 315 drives with rotation
Component 32 drives cleaning case 31 to transfer to realize the rotary motion in rotation holding tank 30 in 3 inward turning of service sink；The rotation connects
Uniformly be fixed at least four idler wheels 316 on 315 top and bottom of socket part respectively, the 30 corresponding top surface of rotation holding tank and
Embedded to be respectively embedded into annular slot rolling 301 corresponding with idler wheel 316, the idler wheel 316 of 315 top and bottom of rotary connector divides
It Dui Ying not be placed in the upper and lower slot rolling 301 of rotation holding tank 30；Stability of the cleaning case 31 in rotary course can so be improved
And smoothness.
Wherein, with reference to Fig. 3, above-mentioned rotary drive assembly 32 includes a rotation driving for being electrically connected to PLC control cabinet 7
Motor 321, driving wheel 322, driven wheel 323 and rotating disk 324,3 inner cavity lower part of the service sink are fixed with a horizontal seat 37, the cross
The inner cavity of service sink 3 is separated into superposed accommodating chamber 38 and positioned at the control room 39 of lower part by seat 37, the cleaning case 31,
Rotating disk 324, rotary drive motor 321 are respectively positioned in accommodating chamber 38 and cleaning case 31 is fixed in rotating disk 324, the active
Wheel 322, driven wheel 323 are respectively positioned in control room 39, and rotary drive motor 321 is connected to driving wheel 322 simultaneously by retarder
Driving wheel 322 is driven to rotate, the rotary shaft 325 for rotatably passing through horizontal seat 37 by one between rotating disk 324 and driven wheel 323
It is fixed together, is linked together by V belt translation between driving wheel 322 and driven wheel 323；Rotary drive motor 321 is in PLC
Realize that driving driving wheel 322 rotates under the manipulation of switch board 7, driving wheel 322 drives driven wheel 323 to rotate by V belt translation, from
Driving wheel 323 drives cleaning case 31 to rotate by rotating disk 324 in turn.
Moreover, on 3 lateral wall of the service sink setting be connected with 3 inner cavity of service sink, openable and closable maintenance door 36, it is described
Outlet pipe 311 that 31 bottom of cleaning case is fixed with a belt switch valve, being connected with 31 inner cavity of cleaning case.The position of the maintenance door 36
The lower part of accommodating chamber 38 in corresponding control room 39 is set, the equipment in control room 39 can be overhauled by opening 36 shell of maintenance door,
Effluent outfall can be connected on outlet pipe 311, sewage in cleaning case 31 to be exhausted after the completion of work to be cleaned, Huo Zheyong
The flushing sewage of cleaning case 31 is rinsed in discharge, it is easy to use.
The water drenching collecting tank 41 of a genesis analysis, and 4 table top of water drenching workbench are embedded on 4 table top of water drenching workbench
On be additionally provided with across the mobile placement table 42 above water drenching collecting tank 41, longitudinally movable, which places on 42 desktop of table
Offer a cross direction profiles, for the suspention traversing traversing placing groove 421 passed through of column 62,421 width of traversing placing groove and cross
It moves that 22 width of gap is equal and traversing 421 right end of placing groove extends to and mobile places 42 desktop right side of table, the water drenching work
4 table top of platform and mobile place are respectively equipped with a positioning instruction icon 43 on 42 desktop of table；When mobile table 42 of placing is moved to two
A positioning instruction icon 43 stops when being aligned and fixed position, at this point, 421 transverse center face of the traversing placing groove and it is traversing between
22 transverse center face of gap is in the same plane；And be fixed on water drenching workbench 4 a belt switch valve, with water drenching collecting tank 41
The drainage pipeline 44 being connected.
Wherein, four 422 bottoms of table leg of above-mentioned mobile placement table 42 are respectively and fixedly provided with movable pulley 423, the water drenching work
Make on 4 table top of platform to be located at the position of the left and right sides of water drenching collecting tank 41 be embedded with respectively a genesis analysis, with 423 phase of movable pulley
Corresponding sliding rail 45, the mobile table 42 of placing are realized with being slidably matched for corresponding sliding rail 45 in water drenching work by movable pulley 423
Make to do straight skidding movement on 4 table top of platform；And correspondence extends to 4 table top of water drenching workbench respectively for the rear and front end of two sliding rails 45
Front and back sides.
After the completion of the block cleaning of 6 inner tissues of frame unit, is promoted in cleaned 5 self-cleaning case 31 of manipulation machine and be displaced to movement
At 421 position of traversing placing groove for placing table 42（The position is located at mobile 42 right side of placement table and is carried out with extended position icon
Label）It puts down, the frame unit 6 being laid down is pushed to mobile 42 left side of table of placing to vacate the corresponding position of extended position icon
It sets, to wait for that frame unit 6 is laid down next time.It is suspended in the mobile frame unit 6 placed on table 42, grip end seat 63 is placed in
It is mobile place on 42 desktop of table, suspention column 62 is placed in traversing placing groove 421, framework 61 be suspended in it is mobile place 42 lower section of table and
Above water drenching collecting tank 41, the tissue block after being cleaned in framework 61 can carry out water drenching, and water falls into water drenching collection
To wait for periodically being discharged from drainage pipeline 44 in slot 41.After table 42 is placed in a movement is piled frame unit 6, you can by this
Mobile table 42 of placing is moved backward along sliding rail 45, another is allowed not put the mobile placement table 42 of frame unit 6 from before sliding rail 45
It holds and carries out sliding rail 45 and be moved to simultaneously fixed position of stopping when two positioning instruction icons 43 are aligned, with to be placed into frame unit 6.
Pile frame unit 6 mobile placement table 42 be pushed to 4 rear end of water drenching workbench after, can also continue to water drenching, water drenchings waited to complete
Afterwards, frame unit 6 is removed from 421 right end of traversing placing groove, you can the door hanging taking-up of opening for opening framework 61 is cleaned, after water drenching
Tissue block, meanwhile, it is next to wait for which can remove water drenching workbench 4 from 45 rear end of sliding rail
Secondary recycling.
Referring to Fig.1 and Fig. 4, the cleaning manipulation machine 5 include a mechanical gripper for being used to capture or decontrol grip end seat 63
51, the lifting drive 52 for driving 51 straight line elevating movement of mechanical gripper and for driving mechanical gripper 51 to do transverse direction
The track of the horizontal driving device 53 of linear reciprocating motion, 51 transverse reciprocating of mechanical gripper linear motion and straight line elevating movement is located at
In the elongated surfaces in 22 transverse center face of traversing gap.
The invention also includes have the supporting rack 11 for being fixed on 1 front side left and right ends of cleaning platform, be fixed on both ends support
Support plate 12 between 11 top of frame, the support plate 12 are laterally distributed in right over service sink 3；The horizontal driving device 53 includes
Have and is laterally distributed in the lead screw 531 of 12 lower section of support plate, is fixedly connected on lead screw 531 and for driving 531 positive and negative rotation of lead screw
Second driving motor 532 is threaded in sliding seat 533 on lead screw 531, and the mechanical gripper 51 passes through lifting drive 52
It is fixed on 533 bottom surface of sliding seat, which is fixed in support plate 12 and is electrically connected to PLC control cabinet 7 simultaneously
It is realized under the manipulation of PLC control cabinet 7 and drives 531 positive and negative rotation of lead screw and then sliding seat 533 is driven to do cross with mechanical gripper 51
To linear reciprocating motion；And 533 top of sliding seat is fixed with the guide pad 534 of a T shapes, the support plate is opened on 12 bottom surface
Equipped with guide rail 121 corresponding with guide pad 534, the sliding seat 533 passes through guide pad 534 and guide rail 121
The realization that is slidably matched can be suspended in horizontal sliding 12 lower section of support plate, can improve 533 traversing stability of sliding seat and guiding
Property.
Wherein, above-mentioned lifting drive 52 includes first electric expansion being fixed on 533 bottom surface of sliding seat
Bar 521, one is fixed on the telescopic drive cylinder 522 on 521 bottom telescopic end of the first electric telescopic rod, the telescopic drive cylinder
Fixed there are one driving plate 523 on 522, the mechanical gripper 51 is fixed on 523 bottom surface of driving plate, first electric expansion
Bar 521, telescopic drive cylinder 522, which are electrically connected to, to be electrically connected in PLC control cabinet 7.Using the first electric telescopic rod 521 and stretch
Contracting driving cylinder 522 can drive driving plate 523 that mechanical gripper 51 is driven to carry out straight line elevating movement.
Wherein, above-mentioned mechanical gripper 51 includes a vertical mullion 511, two being fixed on 523 bottom surface of driving plate
Be rotatably connected on 511 bottom end both sides of mullion grabbing claw 512, two with can spinning upside down respectively is respectively placed in 511 both sides of mullion
The second electric telescopic rod 513, the top of second electric telescopic rod 513 is hinged on 523 bottom surface of driving plate and bottom is stretched
Contracting end is articulated with corresponding grabbing claw 512, and second electric telescopic rod 513 is electrically connected to PLC control cabinet 7 and is controlled in PLC
Realize stretching motion to drive grabbing claw 512 to spin upside down movement under the manipulation of cabinet 7.
63 both sides of grip end seat offer crawl screens slot corresponding with both sides grabbing claw 512 631 respectively；Two are grabbed
It takes pawl 512 to be downwardly turned under the stretching, extension driving effect of the second electric telescopic rod 513 respectively and is caught in corresponding crawl screens slot 631
Interior achievable crawl grip end seat 63, two grabbing claws 512 are upward under the contraction driving effect of the second electric telescopic rod 513 respectively
Lower overturning, which is detached from corresponding crawl screens slot 631, can be achieved to decontrol grip end seat 63.It is above-mentioned about cleaning manipulation machine 5 to screen frame group
The crawl of part 6 or to decontrol operation realized by crawl between mechanical gripper 51 and grip end seat 63 or relieving action.
Meanwhile sewage is discharged cleaning case 31 of the invention by outlet pipe 311 after the completion of tissue block cleaning,
And rack for cleaning 9 is dismantled out of cleaning case 31 and is lifted up to take out, to be cleaned to 31 madial wall of cleaning case.The present invention
Additionally provide a rinsing module 8 for rinsing 31 madial wall of cleaning case；The flushing generated after being rinsed using the rinsing module 8 is dirty
Water can be also discharged by outlet pipe 311.
Wherein, above-mentioned rinsing module 8 includes during a circular fixed disk 81, one is fixed on 81 upper surface of fixed disk
Portion and grip end seat 63 corresponding with mechanical gripper 51, a top be vertically fixed on vertical beam 82 in the middle part of 81 lower surface of fixed disk,
Four are connected to vertical beam around the flushing coaming plate 83 being distributed in around vertical beam 82, each coaming plate 83 that rinses by three layers of connecting plate 84
On 82, four are rinsed coaming plates 83 and surround that one corresponding with 31 madial wall shape of cleaning case and angle of inclination, cross section is
Annular, flushing combination box that longitudinal section is isosceles trapezoid wide at the top and narrow at the bottom, four of the flushing combination box rinse coaming plates 83 with
It is parallel equidistantly distributed between the madial wall of 31 corresponding position of cleaning case.
Each rinse in coaming plate 83 is distributed with a wash tub pipe 86, and each rinse on coaming plate 83 is uniformly fixed with several connections
In the Flushing nozzle 87 of wash tub pipe 86, four wash tub pipes 86 are communicated in the same water delivery manifold, and water delivery manifold passes through electricity
Dynamic water pump is connected to resource of water supply, and the electric water pump is electrically connected to PLC control cabinet 7.Electric water is manipulated using PLC control cabinet 7
Pump work supplies water for each flushing coaming plate 83.Clean the grip end seat 63 that manipulation machine 5 captures rinsing module 8 using mechanical gripper 51
The straight line oscilaltion in cleaning case 31 of rinsing module 8 is driven, while driving cleaning case 31 to rotate using rotary drive assembly 32,
Work is rinsed to cleaning case 31 using each flushing coaming plate 83 is convenient, and flushing effect is good.
It is preferred that in order to which rinsing module 8 can to the top and lower part of 31 madial wall of cleaning case in elevating movement
Short-range flushing is kept, the flushing effect to 31 inner sidewall upper portion of cleaning case is further increased.Flushing group provided by the invention
Part 8, connecting plate 84 are connected to by third electric telescopic rod 85 on vertical beam 82, and third electric telescopic rod 85 is electrically connected to PLC
Switch board 7 and under the manipulation of PLC control cabinet 7 carry out stretching motion be drivingly connected plate 84, rinse coaming plate 83 do transverse reciprocating
Linear movement.And the end that each top layer connecting plate 84 rinsed on coaming plate 83 corresponds to 82 one end of vertical beam is respectively and fixedly provided with a guide holder
88, guide groove 811 corresponding with guide holder 88 is offered on 81 lower surface of fixed disk, and top layer connecting plate 84 passes through guiding
The realization that is slidably matched of seat 88 and guide groove 811 can be suspended in horizontal sliding 81 lower section of fixed disk；Flushing coaming plate can be improved
83 stability and guidance quality during traversing.
As shown in fig. 6, when being cleaned to the top of 31 madial wall of cleaning case using rinsing module 8, controlled using PLC
Cabinet 7, which manipulates 85 stretching, extension of third electric telescopic rod, drives each flushings coaming plate 83 close to its 31 madial wall of corresponding cleaning case, shorten and
Spacing between 31 madial wall of cleaning case improves flushing effect；As shown in fig. 7, being fallen when rinsing module 8 is cleaned manipulation machine 5
When being rinsed to 31 madial wall lower part of cleaning case, PLC control cabinet 7 manipulates third electric telescopic rod 85 and bounces back so that each rinse is enclosed
The reset of plate 83 is encircled into flushing combination box again, and the short distance to 31 madial wall of cleaning case is still kept to rinse；I.e. the present invention carries
Supply by four rinse the flushing combination box that surrounds of coaming plates 83 can merge, it is also detachable, can according to 31 madial wall of cleaning case not
Each state for rinsing coaming plate 83 is adjusted with the demand of height and position to remain that the short distance to 31 madial wall of cleaning case is rushed
It washes, flushing effect is good, strong applicability.
Claims (4)
1. the automatic cleaning equipment for cultivating tissue block needed for stem cell, it is characterised in that：It include a cleaning platform
（1）, one cleaning manipulation machine（5）, it is several for holding the frame unit of tissue block（6）, a PLC control cabinet（7）；
The frame unit（6）Include one for placing tissue block, side wall be equipped with the netted cylindrical frame of retractable switch gate
Body（61）, a vertical distribution and bottom end be fixed on framework（61）Suspention column on top surface（62）, one be fixed on suspention column（62）Top
The grip end seat at end（63）；
The cleaning platform（1）Include frame up workbench of the genesis analysis on right side（2）, a genesis analysis is in left side
Water drenching workbench（4）And one be fixedly connected on the workbench that frames up（2）Front end and water drenching workbench（4）Service sink between front end
（3）；
The workbench that frames up（2）Table top is fixedly arranged at the front end with the fixed placement table of two cross direction profiles（21）, two fixed placements
Table（21）Between be formed with a cross direction profiles, for suspend in midair column（62）The traversing traversing gap passed through（22）, and traversing gap
（22）Width is less than grip end seat（63）Length；Work as frame unit（6）It is placed on two fixed placement tables（21）When, grip end seat（63）It is long
Both ends on degree direction are individually placed to two fixed placement tables（21）On desktop and suspend column in midair（62）It is placed in traversing gap（22）Interior,
Framework（61）It is placed in fixed placement table（21）Below desktop；
The service sink（3）Inside it is equipped with a cleaning case for holding cleaning solution（31）, the cleaning case（31）Inside removably
It is fixed with the circular ring shape wash bowl that a top and bottom end are all provided with opening, are vertically distributed（33）, the traversing gap（22）In transverse direction
The elongated surfaces over cleaning cylinder in heart face（33）Central axis, the wash bowl（33）Side wall is uniformly provided with several recirculation holes（331）, and
Wash bowl（33）A circular ring shape Clean Brush for cleaning is fixed on madial wall（34）, the circular ring shape Clean Brush for cleaning（34）Inner cavity form
With framework（61）Corresponding lifting space（35）；
The water drenching workbench（4）The water drenching collecting tank of a genesis analysis is embedded on table top（41）, and water drenching workbench（4）Platform
It is additionally provided on face across in water drenching collecting tank（41）Top, longitudinally movable mobile placement table（42）, movement placement table
（42）A cross direction profiles are offered on desktop, for suspention column（62）The traversing traversing placing groove passed through（421）, the traversing placement
Slot（421）Width and traversing gap（22）Width is equal and traversing placing groove（421）Right end extends to mobile placement table（42）Table
Right side of face face, the water drenching workbench（4）Table top and mobile placement table（42）A positioning instruction icon is respectively equipped on desktop
（43）；Table is placed when mobile（42）It is moved to two positioning instruction icons（43）It stops when alignment and fixed position, at this point, described
Traversing placing groove（421）Transverse center face and traversing gap（22）Transverse center face is in the same plane；
The cleaning manipulation machine（5）Include one for capturing or decontrol grip end seat（63）Mechanical gripper（51）, for driving
Mechanical gripper（51）The lifting drive of straight line elevating movement（52）And for driving mechanical gripper（51）It is straight to do transverse reciprocating
The horizontal driving device of line movement（53）, the mechanical gripper（51）Transverse reciprocating moves along a straight line and the track of straight line elevating movement is located at cross
Move gap（22）In the elongated surfaces in transverse center face.
2. the automatic cleaning equipment according to claim 1 for cultivating tissue block needed for stem cell, it is characterised in that：Institute
State service sink（3）Setting and service sink on lateral wall（3）Inner cavity is connected, openable and closable maintenance door（36）, the cleaning case
（31）Bottom is fixed with a belt switch valve and cleaning case（31）The outlet pipe that inner cavity is connected（311）.
3. the automatic cleaning equipment according to claim 1 for cultivating tissue block needed for stem cell, it is characterised in that：Institute
State water drenching workbench（4）On be fixed with a belt switch valve, with water drenching collecting tank（41）The drainage pipeline being connected（44）.
4. the automatic cleaning equipment according to claim 1 for cultivating tissue block needed for stem cell, it is characterised in that：Institute
State mobile placement table（42）Four table legs（422）Bottom is respectively and fixedly provided with movable pulley（423）, the water drenching workbench（4）Table top
It is upper to be located at water drenching collecting tank（41）A genesis analysis and movable pulley are embedded at the position of the left and right sides respectively（423）It is corresponding
Sliding rail（45）, the mobile placement table（42）Pass through movable pulley（423）With corresponding sliding rail（45）Be slidably matched realization drenching
Water workstation（4）Straight skidding movement is done on table top；And two sliding rails（45）Rear and front end respectively correspondence extend to water drenching work
Make platform（4）The front and back sides of table top.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810581660.1A CN108715806A (en) | 2018-06-07 | 2018-06-07 | Automatic cleaning equipment for cultivating tissue block needed for stem cell |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810581660.1A CN108715806A (en) | 2018-06-07 | 2018-06-07 | Automatic cleaning equipment for cultivating tissue block needed for stem cell |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108715806A true CN108715806A (en) | 2018-10-30 |
Family
ID=63911930
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810581660.1A Withdrawn CN108715806A (en) | 2018-06-07 | 2018-06-07 | Automatic cleaning equipment for cultivating tissue block needed for stem cell |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108715806A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111040950A (en) * | 2020-01-23 | 2020-04-21 | 中科宝承生物医学科技有限公司 | Stem cell cleaning device and operation method thereof |
| CN114381371A (en) * | 2022-01-13 | 2022-04-22 | 山东大学齐鲁医院 | A adenocarcinoma stem cell culture apparatus for breast cancer immunotherapy |
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| CN106001037A (en) * | 2016-07-20 | 2016-10-12 | 张小云 | Glass machining cleaning frame |
| CN106967586A (en) * | 2017-06-04 | 2017-07-21 | 王玉杰 | The automatic rinser of tissue block needed for for cultivating stem cell |
| CN107350239A (en) * | 2017-07-26 | 2017-11-17 | 陈鹏 | A kind of medical test tube cleaning storage integrated device |
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| CN205576322U (en) * | 2016-04-27 | 2016-09-14 | 南昌华骏汽车配件有限公司 | Auto -parts electrophoresis lacquer treatment facility with perpendicular grabbing device |
| CN106001037A (en) * | 2016-07-20 | 2016-10-12 | 张小云 | Glass machining cleaning frame |
| CN106967586A (en) * | 2017-06-04 | 2017-07-21 | 王玉杰 | The automatic rinser of tissue block needed for for cultivating stem cell |
| CN107350239A (en) * | 2017-07-26 | 2017-11-17 | 陈鹏 | A kind of medical test tube cleaning storage integrated device |
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| CN111040950A (en) * | 2020-01-23 | 2020-04-21 | 中科宝承生物医学科技有限公司 | Stem cell cleaning device and operation method thereof |
| CN114381371A (en) * | 2022-01-13 | 2022-04-22 | 山东大学齐鲁医院 | A adenocarcinoma stem cell culture apparatus for breast cancer immunotherapy |
| CN114381371B (en) * | 2022-01-13 | 2023-11-07 | 山东大学齐鲁医院 | Adenocarcinoma stem cell culture device for breast cancer immunotherapy |
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Application publication date: 20181030 |