CN1086729A

CN1086729A - Softing liver and contracting spleen tablet

Info

Publication number: CN1086729A
Application number: CN93112045A
Authority: CN
Inventors: 付军廷
Original assignee: Individual
Current assignee: Individual
Priority date: 1993-06-30
Filing date: 1993-06-30
Publication date: 1994-05-18
Anticipated expiration: 2013-06-30
Also published as: CN1052157C

Abstract

A kind of Softing liver and contracting spleen tablet that is applicable to the treatment liver cirrhosis, its technical scheme main points are that it contains a certain amount of Radix Ginseng, Radix Angelicae Sinensis, Carapax Eriocheir sinensis, the Rhizoma Atractylodis Macrocephalae, Herba Artemisiae Scopariae, the Radix Astragali, Poria, Fructus Aurantii, Herba Plantaginis, Fructus Schisandrae Chinensis.The present invention is in the treating both the principal and the secondary aspects of a disease at the same time treatment method of inheriting Chinese traditional treatment hepatopathy secret recipe handed down from one's ancestors, learning wildly from other's strong points and develop in conjunction with modern medicine, is specially adapted to acute and chronic hepatitis B and liver cirrhosis, and without any side effects.The present invention also has characteristics such as cost is lower, treatment cycle is short.

Description

Softing liver and contracting spleen tablet

The invention belongs to treatment by Chinese herbs hepatopathy technical field.

As everyone knows, the treatment liver cirrhosis is world today's medical circle a great problem.At present, though it is a lot of to be used for the treatment of the medicine of acute hepatitis B, chronic hepatitis B and liver cirrhosis, but its curative effect is different, as: interferon, compound recipe Ganoderma applanatum (Pers. Ex Wallr) Pat. sheet, liver treasured etc., although they are playing certain therapeutical effect to liver cirrhosis in varying degrees, the imperfection part of their maximums is Zhi Qiben not with regard to being only to control its mark.

The purpose of this invention is to provide a kind of Softing liver and contracting spleen tablet that suppresses liver cirrhosis and radical cure.

The object of the present invention is achieved like this: the component percetage by weight that is contained in its prescription is: Radix Ginseng 5-10 part, Radix Angelicae Sinensis 10-15 part, Carapax Eriocheir sinensis 10-15 part, Rhizoma Atractylodis Macrocephalae 15-20 part, Artemisia anethoicles Mattf 25-30 part, Radix Astragali 15-20 part, Poria 25-30 part, Fructus Aurantii 15-20 part, Herba Plantaginis 10-20 part, Fructus Schisandrae Chinensis 5-10 part.Production technology of the present invention is to adopt those of ordinary skill known, that is: cleaning, fragmentation, decocting boil extractum, oven dry, pulverizing, film-making, sugar coating, and test by the pharmacopeia requirement.

The present invention is inheriting Chinese traditional treatment hepatopathy secret recipe handed down from one's ancestors, the Therapeutic Method of the treating both the principal and the secondary aspects of a disease at the same time of learning wildly from other's strong points and developing in conjunction with modern science, has strengthening the body resistance, promoting blood circulation to remove obstruction in the collateral, heat-clearing and toxic substances removing, warming YANG to promote diuresis, enhancing human body immunity power, recover liver function, improve the solid son of blood matter albumen and blood coagulation, it is unbalance to regulate albumen ratio, reduce portal venous pressure, antiinflammatory, antiviral, effectively promote " three Yang Yin commentaries on classics ", fibrosis, improve the circulation of liver function intestinal, activate the atrophy hepatocyte, the retraction hepatosplenomegaly, hard masses softening and resolving, antitumor, alleviating pain, eliminate superior efficacy such as abdominal distention Cheng Shui, and have no side effect, the present invention also has characteristics such as cost is lower, and treatment cycle is short.

Below will the invention will be further described by concrete clinical example:

Example 1

Choose Radix Ginseng 80 grams, Radix Angelicae Sinensis 120 grams, Carapax Eriocheir sinensis 110 grams, the Rhizoma Atractylodis Macrocephalae 160 grams, Artemisia anethoicles Mattf 300 grams, the Radix Astragali 180 grams, Poria 280 grams, Fructus Aurantii 170 grams, Herba Plantaginis 120 grams, Fructus Schisandrae Chinensis 100 grams ten flavor Chinese medicines earlier, the production technology of knowing through those of ordinary skill, that is: screening earlier, cleaning, after mixing fragmentation according to the above ratio, decoct with distilled water, 6-8 doubly measures and decocted 2 hours for the first time; For the second time 3-4 doubly measures and decocted 1 hour, then through leave standstill, filtration, merging filtrate, concentrating under reduced pressure is made extractum, pulverize the oven dry back, film-making, sugar coating and make finished product.

Method of quality control: outward appearance: complete bright and clean, color and luster is even, hardness is suitable;

The uniformity: get tablet, remove sugar-coat, crushing should be mix homogeneously, color and luster unanimity;

Weight differential: before coating by the pharmacopeia inspection, weight differential must not be greater than ± 5.0%;

Disintegration: press the yellow method inspection of medicine, disintegration is in 30 minutes.

Medicine sanitary test:, up to specification by 171 pages of method inspections of " Chinese People's Liberation Army's medicine preparation standard " appendix.

Usage and consumption: every day three times, each 3-5 sheet, take 30 minutes ante cibum; Children's follows the doctor's advice, and 3 months is a course of treatment.

Through clinical observation 30 routine liver cirrhosis patients, effective percentage 90% after taking this medicine to be month, and a calf brain gland peptide regulating liver-QI treasured and Ganoderma applanatum (Pers. Ex Wallr) Pat. sheet matched group compare, and demonstrates curative effect preferably, and do not find any toxic and side effects.Its selected concrete clinical case is a case 1,2,3.

Example 2

Choose Radix Ginseng 60 grams, Radix Angelicae Sinensis 140 grams, Carapax Eriocheir sinensis 140 grams, the Rhizoma Atractylodis Macrocephalae 180 grams, Artemisia anethoicles Mattf 260 grams, the Radix Astragali 160 grams, Poria 260 grams, Fructus Aurantii 150 grams, Herba Plantaginis 160 grams, Fructus Schisandrae Chinensis 60 grams ten flavor Chinese medicines earlier, its production technology, method of quality control, usage and consumption are same as example 1.Selected clinical case is 4,5,6.

Case 1

The king * *, man, 56 years old.Suffering from liver cirrhosis in 1986, the full Xiang Jun of liver function changes, B ultrasonic prompting spleen rib 3.0cm, abdominal part liquid dark space 3.5, edema of pair of lower extremities (+); Hemogram: total white blood cells 3800, platelet 80,000, this number rises for liver cirrhosis loses and repays the phase.Give 5 of Softing liver and contracting spleen tablets, 3/, 30 minutes ante cibum were oral, after one month, edema of pair of lower extremities disappears, and the check liver function takes an evident turn for the better total white blood cells 5600, platelet 11.2 ten thousand, the B ultrasonic result is 2.0cm under the spleen rib, and abdominal part liquid dark space disappears, and edema of pair of lower extremities disappears, and sb.'s illness took a favorable turn.

Case 2

Open * *, woman, 47 years old.Nineteen ninety suffering from liver cirrhosis, liver function MC,, abdominal distention poor, the slight edema of two lower limb with urging; Hemogram: leukocyte count 4000, platelet 9.2 ten thousand is diagnosed as cirrhosis patients in decompensation.Give 5 of Softing liver and contracting spleen tablets, 3/, 30 minutes ante cibum were oral, subjective symptoms complete obiteration after month, and edema of pair of lower extremities disappears, and liver function is normal, leukocyte 5600, platelet 13.5 ten thousand, sb.'s illness took a favorable turn.

Case 3

All * *, man, 65 years old.Suffering from liver cirrhosis in 1986 is felt sick and is detested oil, and appetite obviously goes down, weak, abdominal distention, and oliguria, yellowish urine, the loose stool, complete of liver function changes, and the white ratio of plasma protein ball is inverted; Hemogram: total white blood cells 2800, platelet 6.2 ten thousand, B ultrasonic: 5.5cm under the spleen rib, abdominal part liquid dark space 5.00, edema of pair of lower extremities (+) is diagnosed as cirrhosis patients in decompensation.Give 5 of Softing liver and contracting spleen tablets, 3/, after oral one month of 30 minutes ante cibum, subjective symptoms obviously alleviated, and edema of pair of lower extremities disappears, and the check liver function is obviously improved, and the white ratio of plasma protein ball increases, total white blood cells 4500, platelet 100,000; B ultrasonic: bounce back to 3.0cm under the spleen rib, liquid dark space 1.0cm, sb.'s illness took a favorable turn.

Case 4

Liu * *, man, 44 years old.Suffered from posthepatitic cirrhosis in 1991, nauseating, appetite obviously goes down, and the whole body is weak, abdominal distention, and oliguria, tooth blood, liver function the enzyme gallbladder occurs and separates, and plasma protein ratio is to putting; Hemogram: leukocyte count 2500, platelet 50,000, B ultrasonic: spleen rib 4.5cm, abdominal part liquid dark space 7.5cm, edema of pair of lower extremities (+) is diagnosed as cirrhosis patients in decompensation (chronic heavy type).Give 5 of Softing liver and contracting spleen tablets, 3/, 30 minutes ante cibum were oral, subjective symptoms disappears substantially after three months, tooth blood stops, and liver function is normal, and plasma protein ratio strengthens, leukocyte 5200, platelet 10.2 ten thousand, 4.0cm under the B ultrasonic spleen rib, abdominal part liquid dark space 2.0cm, it disappears edema of pair of lower extremities, and sb.'s illness took a favorable turn.

Case 5

Permitted * *, woman, 54 years old.Nineteen ninety suffering from liver cirrhosis, poor appetite, abdominal distention, yellowish urine, the liver function MC, the slight edema of two lower limb, 2.5cm under the B ultrasonic prompting spleen rib, total white blood cells 4000, platelet 7.6 ten thousand is diagnosed as cirrhosis patients in decompensation.Give 5 of Softing liver and contracting spleen tablets, 3/ day, after oral one month of 30 minutes ante cibum, the subjective symptoms complete obiteration, edema of pair of lower extremities disappears, and liver function is normal, total white blood cells 6800, platelet 13.2 ten thousand; Sb.'s illness took a favorable turn.

Case 6

South * *, man, 56 years old.Nineteen ninety suffering from liver cirrhosis, that idol has is nauseating, detest oil, weak, abdominal distention, liver function MC; Hemogram: leukocyte count 3800, platelet 50,000 is diagnosed as posthepatitic cirrhosis.Give 5 of Softing liver and contracting spleen tablets, 3/, 30 minutes ante cibum were oral, transference cure after month, and liver function is normal, leukocyte 5200, platelet 9.2 ten thousand, sb.'s illness took a favorable turn.

Claims

1, a kind of Softing liver and contracting spleen tablet that is applicable to the treatment liver cirrhosis is characterized in that it contains: Radix Ginseng 5-10 part, Radix Angelicae Sinensis 10-15 part, Carapax Eriocheir sinensis 10-15 part, Rhizoma Atractylodis Macrocephalae 15-20 part, Artemisia anethoicles Mattf 25-30 part, Radix Astragali 15-20 part, Poria 25-30 part, Fructus Aurantii 15-20 part, Herba Plantaginis 10-20 part, Fructus Schisandrae Chinensis 5-10 part.

2, Softing liver and contracting spleen tablet according to claim 1 is characterized in that the optimum weight portion rate is: 8 parts of Radix Ginsengs, 12 parts of Radix Angelicae Sinensis, 11 parts of Carapax Eriocheir sinensis, 16 parts of the Rhizoma Atractylodis Macrocephalaes, 30 parts of Artemisia anethoicles Mattf, 18 parts of the Radixs Astragali, 28 parts in Poria, 17 parts of Fructus Aurantiis, 12 parts of Herba Plantaginiss, 10 parts of Fructus Schisandrae Chinensis.