CN1086727A

CN1086727A - A kind of treatment gastropathy medicinal liquid stomach peace liquid

Info

Publication number: CN1086727A
Application number: CN 93109974
Authority: CN
Inventors: 李来明
Original assignee: Individual
Current assignee: Individual
Priority date: 1993-08-23
Filing date: 1993-08-23
Publication date: 1994-05-18

Abstract

A kind of stomach peace liquid, it has been selected multiple pure medical material for use and has made, as has selected Semen Coicis, Poria, Fructus Citri etc. for use.For digestive system disease such as chronic gastritis, atrophic gastritis, gastric ulcers significant curative effect is arranged, total effective rate can reach 92.5%.This medicine improves the microcirculation of stomach blood capillary effectively, and strengthen the gastric mucosa regeneration capacity and reach the sick effect of healing, be that a kind of curative effect is fast, side effect is few, extremely has the treatment of extensive future to protect stomachic.

Description

A kind of treatment gastropathy medicinal liquid stomach peace liquid

The invention relates to medical treatment, medicinal liquid (stomach peace liquid) for health care, particularly for the disease of digestive system, as chronic gastritis, comprised that commonly encountered diseases, frequently-occurring diseases such as shallow, atrophic and gastritis ulcerosa have special curative effect.

Gastropathy is exactly a kind of common property frequently-occurring disease since ancient times, its pathogenic factor is often owing to factors such as daily life is careless, chronic fatigue, anxiety are brought out, seriously endanger people health, data shows that the people of the nearly 20-30% of China suffers from gastropathy in various degree according to the relevent statistics.Disease for digestive system nearly all exists the said spleen deficiency of the traditional Chinese medical science, wet because of the stagnation of QI, and therefore traditional methods such as tcm prescription Chang Yicong harmonizing the spleen and stomach, spleen benefiting and stimulating the appetite dyspepsia and intestinal stasis relieving and soothing the liver nourishing the stomach are started with.Present existing Chinese patent medicine have cyperus-amomum stomach, invigorating the spleen and replenishing QI,, gastric qi pain relieving and SANJIU WEITAI afterwards etc.But these medicines have a common shortcoming be the course of treatment long, cure rate is low, easy recurrence, some medicine also needs to take all the year round, makes troubles and painful to the patient.Certainly the medicine of treatment gastropathy also has Western medicine, and Western medicine mainly is employing neutralization or gastric acid inhibitory secretion, absorption or suppresses stomach egg enzyme and treat disease of stomach.Prove from present medical research achievement both domestic and external: helicobacter pylori (HP), people's stomach spirillum (GH), especially helicobacter pylori is the main cause that causes chronic gastritis, just proposes the method for bismuth complex treatment gastric ulcer abroad as far back as the beginning of the forties.Though usually eliminate pathogen on the gastric mucosa in the Western medicine and with bismuth complexing agent and, two kind of antibiosis, can cure the gastritis and the obvious relapse rate of reduction ulcer, ignored the meridian function balance of human body, and Western medicine is taken for a long time and is had certain poison and pay effect.

At present Chinese medicine and the Western medicine weak point for treatment gastropathy, the present inventor has invented stomach peace liquid through concentrating on studies for many years.It is is purport to hold up spleen nourishing the stomach, benefit to build appetizing, adopt kinds of traditional Chinese medicines, mends natural Chinese medicines and high-quality pure grain gentle, Medicine Food Homology and makes, is carefully dished up and forms as Semen Coicis, Huai Shan, Fructus Amomi Rotundus etc. are flat.Its pharmacology is to kill or when suppressing helicobacter pylori, improves gastrointestinal portion blood capillary microcirculation effectively, adjusts the stomach vegetative nerve function, and the nutrition gastric mucosa promotes the generation of the gastric mucosal protection factor.Make the gastric epithelial cell reparation, can be with healings such as cureless peptic ulcer, atrophic gastritis, thus avoided the generation of stomach canceration.In addition for CHANGYANXIAO voltinism diarrhoea and cholelithiasis, cholecystitis also has certain curative effect.

The present inventor thinks that also a large amount of excessive drinking meetings damage human body; but the pure grain wine of trace can inrigorating qi and promoting blood circulation to human body; awake stomach promotes the production of body fluid; utilize the Xin Wenganre of wine, unobstructed blood vessels effectively improve stomach blood capillary microcirculation, and the Chinese medicine material is absorbed very soon; make stomach produce a substantive nutrition protective layer; wine assisting drug has been given full play to its therapeutical effect, and the ethanol content in the general medicinal liquid is 38-60%, and is 15-38% for women and children's type.

Wherein Chinese medicinal ingredients (is unit with g) (comprising relative scale) is as follows:

Semen Coicis 400～600g Oryza glutinosa 600～700g

Poria 100～140g Rhizoma Dioscoreae 100～140g

Fructus Amomi 50～70g Fructus Amomi Rotundus 50～70g

Semen Pruni 50～70g MUZHUA 50～70g

Fructus Citri Sarcodactylis 70～100g citron 70～100g

Semen Raphani 70～100g Fructus Armeniacae Mume 50～70g

Semen Ziziphi Spinosae 50～70g Cordyceps 100～140g

Fructus Setariae Germinatus 100～140g Concha Ostreae 100～140g

Massa Medicata Fermentata 1009～140g, Fructus Jujubae 200～220g

Manufacture method is as follows, gets above-mentioned scope amount or relative scale amount Chinese medicine at first carries out:

Semen Coicis is concocted: remove impurity, get clean Semen Coicis, fry to little yellow according to frying the bran method;

Rhizoma Dioscoreae is concocted: fry to yellow according to frying the bran method;

Concha Ostreae is concocted: pulverize after the conventional processing forging.

1. at first that the Semen Coicis of the above-mentioned process of preparing Chinese medicine is red, Oryza glutinosa soaked 1-3 hour with clear water, and control is anhydrated, and dries in the shade 1-2 hour, steams the maturation to 6-8, admixed Massa Medicata Fermentata when reducing to temperature to 29 ℃-31 ℃, after 48 hours, kept 34-38 ℃ of temperature stand-by after 72 hours.

2. after then Concha Ostreae, Rhizoma Dioscoreae and Poria, Cordyceps being added water boil, in the time of 75 ℃, soak 5-6 hour extracting juice.

3. get above-mentioned Semen Raphani, SUANZAOHONG, Semen Pruni, Fructus Armeniacae Mume, Fructus Amomi Rotundus and decoct with water secondary, 3 hours for the first time, 1 hour for the second time, extracting juice.

4. MUZHUA, Fructus Amomi, Fructus Citri Sarcodactylis, citron, jujube pulp, Fructus Setariae Germinatus are made solvent according to the percolation of fluid extract and extractum with 65% pure grain wine, soak after 72 hours with above-mentionedly 1. 2. 3. merge, mixing, adjust ethanol content to 38-60% with ethanol and sterilized water, place 20-28 ℃ to continue down to soak 140-180 hour, percolation, lixiviating solution filter the filling bag can obtain orange-yellow transparency liquid.

This product has been selected multiple rare medicinal herbs and fine pure grain wine for use, utilize modern production technology formulated a kind of up-to-date healthcare products meticulously, this stomach peace liquid contains chemical addition agents such as multiple defying age material, preservative free, there is not the effect of paying, so it is compared with traditional stomach medicine by improving the microcirculation of stomach blood capillary, increase stomach cell regeneration function and reach therapeutic purposes, through the clinical examination of related hospitals danger result, effective percentage is up to 92.5%.

Stomach peace liquid of the present invention is to the acute toxicity test of white mice

Stomach peace liquid is yellow liquid, is to contain 53% alcoholic acid colourfully decorated lantern cephalic flexure wine to add an amount of Chinese medicine formulated with commercially available.

Test method and result:

1, LD50 measures: 50 of Kunming kind white mice, five groups, every group 10 of branches, male and female half and half, 19-21 restrain (the animal breeding field provides), fasting is 2 hours before the administration, and every group of agent distance by 1: 0.9 established: 27.00ml/Kg, 24.30ml/Kg, 21.37ml/Kg, 19.68ml/Kg, five dosage groups of 17.71ml/Kg.The oral stomach peace of white mice liquid was observed seven days after the administration, recorded LD50 ≈ 22.2794ml/Kg, LD95 ≈ 25.2862ml/Kg, the LD5 ≈ 19.631ml/Kg of stomach peace liquid.

2, continuous seven days administration toxicity tests: stomach peace liquid people consumption is: 12ml/ time, and three times/day, add up to 0.6ml/kg.Get 120 of Kunming white mice, divide six groups, 20 every group, male and female half and half, 18～20 grams.According to 0.6nml/kg people's consumption meter: stomach peace liquid 30ml/kg, 15ml/kg, 7.5ml/kg, 3.75ml/kg, be equivalent to 50 times, 25 times, 12.5 times, 6.25 times of people's consumption and solvent colourfully decorated lantern wine 30ml/kg, 7.5ml/kg dosage group respectively, and establish the distilled water matched group.Administration every day totally respectively is 30ml/kg/, divides in 24 hours and irritates stomach, continuous seven days three times.

After the administration, the stomach of 3.75ml/kg peace liquid group body weight shows a rising trend, and other group body weight increases with dosage, slightly increases slowly, but 14 day convalescent period is respectively organized body weight and show a rising trend.

Dead 7 of 30ml/kg stomach peace liquid group, dead 14 of 30ml/kg colourfully decorated lantern wine group, dead animal is through dissecting, and most gastrointestinal gas that rise that are are found in perusal.

Behind the successive administration 7 days, live to kill each line animal, perusal no abnormality seen, and the weight of satisfactory, liver, spleen, lung, kidney, stomach, each organ coefficient is handled through the t inspection statistics and is not seen significant difference, for details see attached table.

3.75ml/kg, 7.5ml/kg and 15ml/kg administration group, 7.5ml/kg group of solvents and distilled water matched group there is no animal dead.

Claims

1, the stomach peace liquid that a kind of medical treatment, health care stomach are used is characterized in that being mixed with pure Chinese medicine and pure grain wine.

2, according to claim 1, pure Chinese medicine wherein is to be made of following composition:

Semen Coicis, Oryza glutinosa, Poria, Rhizoma Dioscoreae, Fructus Amomi, Fructus Amomi Rotundus, Semen Pruni, MUZHUA, Fructus Citri Sarcodactylis, citron, Semen Raphani, Fructus Armeniacae Mume, Semen Ziziphi Spinosae, Cordyceps, Fructus Setariae Germinatus, Concha Ostreae, Massa Medicata Fermentata, Fructus Jujubae.

3, as follows according to claim 1, wherein Chinese medicine ingredients amount:

Semen Coicis 400～600g Oryza glutinosa 600～700g

Poria 100～140g Rhizoma Dioscoreae 100～140g

Fructus Amomi 50～70g Fructus Amomi Rotundus 50～70g

Semen Pruni 50～70g Fructus Chaenomelis 50～70g

Fructus Citri Sarcodactylis 70～100g citron 70～100g

Semen Raphani 70～100g Fructus Armeniacae Mume 50～70g

Semen Ziziphi Spinosae 50～70g Cordyceps 100～140g

Fructus Setariae Germinatus 100～140g Concha Ostreae 100～140g

Massa Medicata Fermentata 1009～140g Fructus Jujubae 200～220g

4, the manufacture method of stomach peace liquid is characterized in that giving earlier heart of a lotus seed Ci Ren being concocted and removes impurity, takes out clean Semen Coicis and fries to little yellow according to frying the bran method; DUISHANYAO is concocted and is fried to yellow; The Concha Ostreae process of preparing Chinese medicine is processed into powder with conventional method, then:

1. Semen Coicis, Oryza glutinosa are steamed maturation, admix Massa Medicata Fermentata after the cooling to 6-8;

2. after Concha Ostreae, Rhizoma Dioscoreae, Poria, Cordyceps add water boil, soak juice;

3. Semen Raphani, Semen Ziziphi Spinosae, Semen Pruni, Fructus Armeniacae Mume, Fructus Amomi Rotundus decoct with water the secondary extracting juice;

4. MUZHUA, Fructus Amomi, Fructus Citri Sarcodactylis, citron, jujube pulp, Fructus Setariae Germinatus make extractum, and the pure grain wine of reuse 65% soaks after 72 hours and 1. 2. 3. merges with above-mentioned, then adjusts ethanol content with ethanol and sterilized water and obtains.

5, stomach is pacified the dosage form of liquid, it is characterized in that the dosage form of medicated wine formula.

6, a kind of stomach peace liquid is characterized in that being used for the treatment of and the medicine of the gastropathy that keeps healthy.