CN108671006A - 党参鲜提真空干燥粉末饮片 - Google Patents
党参鲜提真空干燥粉末饮片 Download PDFInfo
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- CN108671006A CN108671006A CN201810733388.4A CN201810733388A CN108671006A CN 108671006 A CN108671006 A CN 108671006A CN 201810733388 A CN201810733388 A CN 201810733388A CN 108671006 A CN108671006 A CN 108671006A
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- radix codonopsis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/13—Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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Abstract
本发明公布了一种“党参鲜提真空干燥粉末饮片”,其主要特征在于:在党参采收后,趁鲜洗涤、切片、榨汁、提取,提取液浓缩成清膏后,再真空干燥至含水量少于12%,粉碎、过筛后真空包装。本饮片质量稳定,既可以入汤剂煎煮,也可以直接入丸剂、散剂、片剂、胶囊剂,利于携带,临床使用方便。
Description
技术领域
本发明属于中药饮片技术领域,尤其属于党参饮片的加工领域。
背景技术
中药党参为桔梗科植物党参、素花党参或川党参的干燥根。党参具有健脾益肺,养血生津的功效。常用于脾肺气虚,食少倦怠,咳嗽虚喘,气血不足等的治疗,是一味常用的中药。传统党参的加工方法为:将药材采挖后,直接晒干/晾干,捆扎打包,储运。到饮片厂后,再洗涤、润软、切片、干燥、包装。此类饮片体积大,卫生学标准差,易于受潮、长霉、生虫,不利于保管,储存和运输成本高。此外,这样的党参饮片质量稳定性差,临床疗效难以保障,病人服用不方便,起效慢。因此,开发一种质量稳定可靠、储存/运输成本低、利于保管、携带和使用方便、起效快的新型党参饮片,势在必行。目前市场上的党参饮片,除了传统饮片之外,还有超微粉饮片和浓缩颗粒饮片两种形式,但两者都是以传统饮片为原料,其质量决定于传统饮片的质量,且超微饮片不能解决药材污染的问题;浓缩颗粒只能提取出水溶性成分。
发明内容
本发明公布了一种“党参鲜提真空干燥粉末饮片”,其主要特征在于:在党参采收后,及时净选,去除泥沙等杂质和非药用部位,于24小时内趁鲜用自来水洗净并切成2~5mm厚的片。将此切好的片加入1~5倍重量50~70℃的水中,浸泡并时时搅拌5~30分钟,过滤,药渣压榨取汁。所得药渣中再加入5~10倍重量的水,煮沸10~30分钟,趁热过滤,药渣再次榨汁,收集药汁。合并上述药汁,过60~100目筛,减压浓缩,温度为50~75℃,浓缩至相对密度为1.15~1.25的清膏。将所得的清膏在60~80℃下真空干燥至含水量低于12%,粉碎,过60目筛,真空包装,即得成品。本党参饮片临床一般使用量为1~5g,既可入汤剂煎服、冲服,也可直接入丸剂、散剂、胶囊剂及片剂中,从而大大提高了临床使用的便捷性和顺应性,有利于临床急症的治疗。
本发明解决了传统党参饮片体积庞大、储运成本高、不利于保管、易生霉生虫、卫生学条件差、质量不稳定等诸多缺点,由于是趁鲜提取,质量比超微粉碎饮片和浓缩颗粒饮片更好。
具体实施例
将党参药材采收后,净选,除去泥沙等杂质和非药用部位,在6小时内趁鲜用自来水洗净,并切成3mm厚的片。将此片加入5倍重量的70℃的纯净水,搅拌30分钟,过滤,药渣压榨取汁。 再往上述药渣中再加入8倍重量的纯净水,煮沸20分钟提取,趁热过滤,药渣再次榨汁,收集药汁。合并上述药汁,减压浓缩,温度为设定为70℃,浓缩至相对密度为1.20的清膏。将所得的清膏于80℃下真空干燥至含水量为8%,粉碎,过60目筛,真空包装,即得成品。
Claims (2)
1.一种党参鲜提真空干燥粉末饮片,其主要特征在于:在党参采收后,及时净选,去除泥沙等杂质和非药用部位,于24小时内趁鲜用自来水洗净并切成2~5mm厚的片,加入1~5倍重量50~70℃的水,浸泡并时时搅拌5~30分钟,过滤,药渣压榨取汁;所得药渣中再加入5~10倍重量的水,煮沸10~30分钟,趁热过滤,药渣再次榨汁,收集药汁;合并上述药汁,过60~100目筛,减压浓缩,温度为50~75℃,浓缩至相对密度为1.15~1.25的清膏;将所得的清膏在60~80℃下真空干燥至含水量低于12%,粉碎,过60目筛,真空包装,即得成品。
2.根据权利要求1所述的党参鲜提真空干燥粉末饮片,其主要特征在于:临床一般使用量为1~5g,既可入汤剂煎服、冲服,也可直接入丸剂、散剂、胶囊剂及片剂中。
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CN201810733388.4A CN108671006A (zh) | 2018-07-06 | 2018-07-06 | 党参鲜提真空干燥粉末饮片 |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110123861A (zh) * | 2019-07-04 | 2019-08-16 | 山西和仁堂中药饮片有限责任公司 | 一种党参饮片的制备方法 |
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2018
- 2018-07-06 CN CN201810733388.4A patent/CN108671006A/zh not_active Withdrawn
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110123861A (zh) * | 2019-07-04 | 2019-08-16 | 山西和仁堂中药饮片有限责任公司 | 一种党参饮片的制备方法 |
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