CN108635527A - A kind of drug and preparation method thereof for treating rhinitis - Google Patents

A kind of drug and preparation method thereof for treating rhinitis Download PDF

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CN108635527A
CN108635527A CN201810940825.XA CN201810940825A CN108635527A CN 108635527 A CN108635527 A CN 108635527A CN 201810940825 A CN201810940825 A CN 201810940825A CN 108635527 A CN108635527 A CN 108635527A
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parts
drug
campanulaceae
propolis
borneol
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朱玉珍
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/64—Insects, e.g. bees, wasps or fleas
    • A61K35/644—Beeswax; Propolis; Royal jelly; Honey
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/34—Campanulaceae (Bellflower family)
    • A61K36/346—Platycodon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A61K36/355—Lonicera (honeysuckle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/42—Cucurbitaceae (Cucumber family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634—Forsythia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/78—Saururaceae (Lizard's-tail family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants

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Abstract

The present invention discloses a kind of drug for treating rhinitis, it includes the raw material of following weight proportioning：23 45 parts of cordate houttuynia, 6 12 parts of the root of Dahurain angelica, 39 parts of honeysuckle, 10 15 parts of campanulaceae, 13 15 parts of rhizoma imperatae, 68 parts of Rhizoma Chuanxiong, 13 17 parts of Fructus Forsythiae, 5 15 parts of borneol, 5 15 parts of luffa vine, 13 parts of Radix Glycyrrhizae, 68 parts of radix scutellariae, 58 parts of propolis.Preparation method includes the following steps：(1) cordate houttuynia, the root of Dahurain angelica, honeysuckle, Rhizoma Chuanxiong, Fructus Forsythiae, borneol, luffa vine, Radix Glycyrrhizae are put into container, it is added in cold boiling water and impregnates 30min, then the clarified solution of soaked drug and soak medicine is put into marmite together again, the cold boiling water for injecting medicine 50mm carries out first time high heat decoction, turn slow boiling tanning, leaching first time liquid again；(2) propolis, campanulaceae, rhizoma imperatae, radix scutellariae are ground respectively to powdered, obtain medicinal powder；(3) it prepares and filters to obtain second of liquid.Present invention optimizes therapeutic effects.Shorten the course for the treatment of and reduces side effect.

Description

A kind of drug and preparation method thereof for treating rhinitis
Technical field
The present invention relates to a kind of drugs, refer in particular to a kind of drug and preparation method thereof for treating rhinitis.
Background technology
Rhinitis is a kind of (containing nasosinusitis, allergic rhinitis) because of lung, caused by spleen, kidney deficiency be weak, heresy of chill or wind-heat is invaded Nasal membrane infectious diseases.Clinic is with ictal nasal obstruction, rhiocnesmus, sneeze, runny nose headache and dizzy, failure of memory and concha Enlargement is a kind of common disease, the frequently-occurring disease of cardinal symptom.Rhinitis not only influences nose, throat and eyes, can also influence to sleep, listen Power, or even headache, dizzy, loss of appetite, easily tired, failure of memory etc..When influencing the physiological function of nasal cavity, it may appear that exhale Obstacle is inhaled, lowered blood oxygen is caused, influences function and the metabolism of other tissues and organ.Currently, being used to treat rhinitis on the market There are many drugs, but is mostly treated using hormonal medicaments, and therapeutic effect is bad, and the course for the treatment of is long, and side effect is big, is easy repeatedly.In Medical treatment rhinitis curative effect is reliable, and toxic side effect is small, has broad prospects.
In view of this, the present inventor specially devises a kind of drug and preparation method thereof for treating rhinitis, thus this case is produced It is raw.
Invention content
The purpose of the present invention is to provide a kind of drugs and preparation method thereof for treating rhinitis, to optimize therapeutic effect.Contracting Low doses and reduction side effect.
In order to achieve the above objectives, solution of the invention：
A kind of drug for treating rhinitis, it includes the raw material of following weight proportioning：23-45 parts of cordate houttuynia, 6-12 parts of the root of Dahurain angelica, 3-9 parts of honeysuckle, 10-15 parts of campanulaceae, 13-15 parts of rhizoma imperatae, 6-8 parts of Rhizoma Chuanxiong, 13-17 parts of Fructus Forsythiae, 5-15 parts of borneol, luffa vine 5-15 parts, 1-3 parts of Radix Glycyrrhizae, 6-8 parts of radix scutellariae, 5-8 parts of propolis.
A kind of drug for treating rhinitis, it includes the raw material of following weight proportioning：45 parts of cordate houttuynia, 6 parts of the root of Dahurain angelica, honeysuckle 3 parts, 15 parts of campanulaceae, 15 parts of rhizoma imperatae, 7 parts of Rhizoma Chuanxiong, 13 parts of Fructus Forsythiae, 15 parts of borneol, 15 parts of luffa vine, 3 parts of Radix Glycyrrhizae, 6 parts of radix scutellariae, 5 parts of propolis.
A kind of drug for treating rhinitis, it includes the raw material of following weight proportioning：23 parts of cordate houttuynia, 12 parts of the root of Dahurain angelica, gold and silver Spend 9 parts, 10 parts of campanulaceae, 13 parts of rhizoma imperatae, 8 parts of Rhizoma Chuanxiong, 17 parts of Fructus Forsythiae, 5 parts of borneol, 15 parts of luffa vine, 1 part of Radix Glycyrrhizae, radix scutellariae 8 Part, 8 parts of propolis.
A kind of drug for treating rhinitis, it includes the raw material of following weight proportioning：30 parts of cordate houttuynia, 9 parts of the root of Dahurain angelica, honeysuckle 6 parts, 12 parts of campanulaceae, 14 parts of rhizoma imperatae, 6 parts of Rhizoma Chuanxiong, 15 parts of Fructus Forsythiae, 10 parts of borneol, 5 parts of luffa vine, 2 parts of Radix Glycyrrhizae, 7 parts of radix scutellariae, 6 parts of propolis.
A method of above-mentioned drug being prepared, it includes the following steps：
(1) cordate houttuynia, the root of Dahurain angelica, honeysuckle, Rhizoma Chuanxiong, Fructus Forsythiae, borneol, luffa vine, Radix Glycyrrhizae are put into container, cold open is added 30min is impregnated in water, and then the clarified solution of soaked drug and soak medicine is put into marmite together again, injected medicine The cold boiling water of 50mm carries out first time high heat decoction, when decocting to 15min, turns slow boiling tanning 35min, leaching first time medicine Liquid；
(2) propolis, campanulaceae, rhizoma imperatae, radix scutellariae are ground respectively to powdered, and is mixed, and medicinal powder is obtained；
(3) medicinal powder is entered in first time liquid, is boiled by intense fire, then with being cooked by slow fire 20 minutes, filtered to obtain second Liquid.
After adopting the above scheme, the present invention be selection cordate houttuynia, the root of Dahurain angelica, honeysuckle, Rhizoma Chuanxiong, Fructus Forsythiae, borneol, luffa vine, Radix Glycyrrhizae, propolis, campanulaceae, rhizoma imperatae, radix scutellariae are combined preparation, make each efficacy of drugs generate collaboration these pharmaceutical compositions Effect, so as to effectively treat rhinitis, the present invention is based on the principle of Chinese traditional treatment rhinitis, effective bactericidal antiphlogistic, supplement dimension life Element, from basic treatment rhinitis, short treating period, curative effect is fast.
Specific implementation mode
A kind of drug for treating rhinitis that the present invention discloses, it includes the raw material of following weight proportioning：Cordate houttuynia 23-45 Part, 6-12 parts of the root of Dahurain angelica, 3-9 parts of honeysuckle, 10-15 parts of campanulaceae, 13-15 parts of rhizoma imperatae, 6-8 parts of Rhizoma Chuanxiong, 13-17 parts of Fructus Forsythiae, ice 5-15 parts of piece, 5-15 parts of luffa vine, 1-3 parts of Radix Glycyrrhizae, 6-8 parts of radix scutellariae, 5-8 parts of propolis.
Embodiment 1
A kind of drug for treating rhinitis, it includes the raw material of following weight proportioning：45 parts of cordate houttuynia, 6 parts of the root of Dahurain angelica, honeysuckle 3 parts, 15 parts of campanulaceae, 15 parts of rhizoma imperatae, 7 parts of Rhizoma Chuanxiong, 13 parts of Fructus Forsythiae, 15 parts of borneol, 15 parts of luffa vine, 3 parts of Radix Glycyrrhizae, 6 parts of radix scutellariae, 5 parts of propolis.
Embodiment 2
A kind of drug for treating rhinitis, it includes the raw material of following weight proportioning：23 parts of cordate houttuynia, 12 parts of the root of Dahurain angelica, gold and silver Spend 9 parts, 10 parts of campanulaceae, 13 parts of rhizoma imperatae, 8 parts of Rhizoma Chuanxiong, 17 parts of Fructus Forsythiae, 5 parts of borneol, 15 parts of luffa vine, 1 part of Radix Glycyrrhizae, radix scutellariae 8 Part, 8 parts of propolis.
Embodiment 3
A kind of drug for treating rhinitis, it includes the raw material of following weight proportioning：30 parts of cordate houttuynia, 9 parts of the root of Dahurain angelica, honeysuckle 6 parts, 12 parts of campanulaceae, 14 parts of rhizoma imperatae, 6 parts of Rhizoma Chuanxiong, 15 parts of Fructus Forsythiae, 10 parts of borneol, 5 parts of luffa vine, 2 parts of Radix Glycyrrhizae, 7 parts of radix scutellariae, 6 parts of propolis.
Present invention further teaches a kind of methods preparing above-mentioned drug, it includes the following steps：
(1) cordate houttuynia, the root of Dahurain angelica, honeysuckle, Rhizoma Chuanxiong, Fructus Forsythiae, borneol, luffa vine, Radix Glycyrrhizae are put into container, cold open is added 30min is impregnated in water, and then the clarified solution of soaked drug and soak medicine is put into marmite together again, injected medicine The cold boiling water of 50mm carries out first time high heat decoction, when decocting to 15min, turns slow boiling tanning 35min, leaching first time medicine Liquid；
(2) propolis, campanulaceae, rhizoma imperatae, radix scutellariae are ground respectively to powdered, and is mixed, and medicinal powder is obtained；
(3) medicinal powder is entered in first time liquid, is boiled by intense fire, then with being cooked by slow fire 20 minutes, filtered to obtain second Liquid.
Application method：Second of liquid is taken daily, it is 2-3 times daily, it continuously takes 15 days or more.
Above-mentioned preparation method is simple, and cost is relatively low, can efficiently extract the ingredient of each drug, gives full play to each drug work( Effect.
Model case：Through clinical conditions patients with rhinitis totally 1655, the age is 862 of 25 years old or more, there is 793 It is 25 years old or less.That fully recovers in 1655 patients has 1025, effective 439, invalid 191.Total effective rate is up to 88%.
The present invention be selection cordate houttuynia, the root of Dahurain angelica, honeysuckle, Rhizoma Chuanxiong, Fructus Forsythiae, borneol, luffa vine, Radix Glycyrrhizae, propolis, campanulaceae, Rhizoma imperatae, radix scutellariae are combined preparation, make each efficacy of drugs generate synergistic effect these pharmaceutical compositions, so as to have Effect treatment rhinitis, the present invention is based on the principle of Chinese traditional treatment rhinitis, effective bactericidal antiphlogistic, replenishing vitamins, from basic treatment nose Inflammation, short treating period, curative effect are fast.
The product form and style of above-described embodiment and the non-limiting present invention, the ordinary skill people of any technical field The appropriate changes or modifications that member does it all should be regarded as the patent category for not departing from the present invention.

Claims (5)

1. a kind of drug for treating rhinitis, it is characterised in that：It includes the raw material of following weight proportioning：It is 23-45 parts of cordate houttuynia, white 6-12 parts of the root of Dahurian angelica, 3-9 parts of honeysuckle, 10-15 parts of campanulaceae, 13-15 parts of rhizoma imperatae, 6-8 parts of Rhizoma Chuanxiong, 13-17 parts of Fructus Forsythiae, borneol 5-15 Part, 5-15 parts of luffa vine, 1-3 parts of Radix Glycyrrhizae, 6-8 parts of radix scutellariae, 5-8 parts of propolis.
2. a kind of drug for treating rhinitis according to claim 1, it is characterised in that：It includes the original of following weight proportioning Material：45 parts of cordate houttuynia, 6 parts of the root of Dahurain angelica, 3 parts of honeysuckle, 15 parts of campanulaceae, 15 parts of rhizoma imperatae, 7 parts of Rhizoma Chuanxiong, 13 parts of Fructus Forsythiae, borneol 15 Part, 15 parts of luffa vine, 3 parts of Radix Glycyrrhizae, 6 parts of radix scutellariae, 5 parts of propolis.
3. a kind of drug for treating rhinitis according to claim 1, it is characterised in that：It includes the original of following weight proportioning Material：23 parts of cordate houttuynia, 12 parts of the root of Dahurain angelica, 9 parts of honeysuckle, 10 parts of campanulaceae, 13 parts of rhizoma imperatae, 8 parts of Rhizoma Chuanxiong, 17 parts of Fructus Forsythiae, borneol 5 Part, 15 parts of luffa vine, 1 part of Radix Glycyrrhizae, 8 parts of radix scutellariae, 8 parts of propolis.
4. a kind of drug for treating rhinitis according to claim 1, it is characterised in that：It includes the original of following weight proportioning Material：30 parts of cordate houttuynia, 9 parts of the root of Dahurain angelica, 6 parts of honeysuckle, 12 parts of campanulaceae, 14 parts of rhizoma imperatae, 6 parts of Rhizoma Chuanxiong, 15 parts of Fructus Forsythiae, borneol 10 Part, 5 parts of luffa vine, 2 parts of Radix Glycyrrhizae, 7 parts of radix scutellariae, 6 parts of propolis.
5. a kind of method preparing claim 1-4 any one of them drugs, it is characterised in that：It includes the following steps：
(1) cordate houttuynia, the root of Dahurain angelica, honeysuckle, Rhizoma Chuanxiong, Fructus Forsythiae, borneol, luffa vine, Radix Glycyrrhizae are put into container, are added in cold boiling water 30min is impregnated, then the clarified solution of soaked drug and soak medicine is put into marmite together again, injected medicine 50mm's Cold boiling water carries out first time high heat decoction, when decocting to 15min, turns slow boiling tanning 35min, leaching first time liquid；
(2) propolis, campanulaceae, rhizoma imperatae, radix scutellariae are ground respectively to powdered, and is mixed, and medicinal powder is obtained；
(3) medicinal powder is entered in first time liquid, is boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second of liquid.
CN201810940825.XA 2018-08-17 2018-08-17 A kind of drug and preparation method thereof for treating rhinitis Withdrawn CN108635527A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112237619A (en) * 2019-07-16 2021-01-19 天津泰源中草药技术开发有限公司 Traditional Chinese medicine for treating rhinitis and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112237619A (en) * 2019-07-16 2021-01-19 天津泰源中草药技术开发有限公司 Traditional Chinese medicine for treating rhinitis and preparation method thereof

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Application publication date: 20181012