CN108619441A - It is a kind of to treat infertile pharmaceutical composition and its preparation method and application - Google Patents
It is a kind of to treat infertile pharmaceutical composition and its preparation method and application Download PDFInfo
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- CN108619441A CN108619441A CN201810805650.1A CN201810805650A CN108619441A CN 108619441 A CN108619441 A CN 108619441A CN 201810805650 A CN201810805650 A CN 201810805650A CN 108619441 A CN108619441 A CN 108619441A
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Abstract
Infertile pharmaceutical composition is treated the present invention provides a kind of, the bulk pharmaceutical chemicals matched by following weight are prepared into：20~30 parts of the fruit of Chinese wolfberry, 15~25 parts of , dodders, 10~20 parts of ginseng, 10~15 parts of Chinese cassia tree, 15~20 parts of fructus alpiniae oxyphyllae, 10~20 parts of longan, 15~30 parts of raspberry, 20~40 parts of Herba Epimedii, 15~25 parts of thizoma curculiginis, 15~20 parts of Hangzhoupro Morinda offcinalis How.The present invention also provides a kind of soft extracts being prepared by aforementioned pharmaceutical compositions.The present invention also provides the preparation methods and purposes of aforementioned pharmaceutical compositions and soft extract.The pharmaceutical composition of the present invention has with bowl spares rushes down, and advantageous in puckery, the compatible experiments of sun are helped in tonifying yin, the symptoms such as impotence infertility, the premature ejaculation of passing out semen caused by kidney-yang deficiency can be obviously improved, and raw materials used medicine is integration of drinking and medicinal herbs medicinal material in side, is had no toxic and side effect to human body, and can be taken for a long time.
Description
Technical field
Present invention relates particularly to a kind of preparation method for treating infertile pharmaceutical composition and the pharmaceutical composition and
Purposes.
Background technology
Kidney-yang deficiency, mostly by innate deficiency of YANG in the body, or old deficiency of the kidney or prolonged illness is impairment of the kidney and the factors such as excess of sexual intercourse,indulgence in sexual activities cause.Kidney yang
Much more empty have a cold of insufficiency type symptoms such as the cold, hands and feet being not warm of chilly, severe patient's impotence premature ejaculation or even infertile.
Since operating pressure is big, lead to immunologic hypofunction, and then the insufficiency of both the spleen and the kindey, sexual function indifference, infertile people
Group is more and more, and it is larger to be accordingly used in pharmaceutical market demand infertile caused by treatment kidney-yang deficiency.But currently used for prevention
Infertile integration of drinking and medicinal herbs kind caused by the insufficiency of both the spleen and the kindey quite lacks, especially safe and non-toxic, the reliable less varieties of curative effect it
It is again few, it can be obviously improved Chinese medicine composition infertile caused by kidney-yang deficiency, and having no toxic and side effect to human body there is an urgent need for a kind of.
It now has no and the relevant report of the present composition.
Invention content
To solve the above problems, treating infertile pharmaceutical composition the present invention provides a kind of.
The pharmaceutical composition of the present invention, it is the preparation that the bulk pharmaceutical chemicals matched by following weight are prepared into：
15~20 parts of fructus alpiniae oxyphyllae, 10~20 parts of longan, 15~30 parts of raspberry, 20~40 parts of Herba Epimedii, thizoma curculiginis 15~25
Part, 15~20 parts of Hangzhoupro Morinda offcinalis How, 10~15 parts of fennel seeds, 20~40 parts of Chinese yam.
Further, it is the preparation that the bulk pharmaceutical chemicals comprising following weight proportioning are prepared into：
25 parts of the fruit of Chinese wolfberry, 20 parts of , dodders, 15 parts of ginseng, 13 parts of Chinese cassia tree, 18 parts of fructus alpiniae oxyphyllae, 15 parts of longan, raspberry 22
Part, 30 parts of Herba Epimedii, 20 parts of thizoma curculiginis, 10 parts of fennel seeds, 17 parts of Hangzhoupro Morinda offcinalis How, 20 parts of Chinese yam.
Wherein, aforementioned pharmaceutical compositions also include the bulk pharmaceutical chemicals of following weight proportioning：
15~20 parts of semen allii tuberosi, 7~10 parts of Schisandra chinensis, 15~20 parts of plantain seed, 15~30 parts of Herba Cistanches, cynomorium songaricum 15~25
Part, 7~15 parts of burnt cypress, 7~15 parts of rhizoma anemarrhenae, 7~15 parts of fructus amomi, 10~15 parts of Radix Angelicae Sinensis, 20~30 parts of English walnut, jujube 20~30
Part.
Further, aforementioned pharmaceutical compositions are the preparations that the bulk pharmaceutical chemicals matched by following weight are prepared into：
25 parts of the fruit of Chinese wolfberry, 20 parts of , dodders, 15 parts of ginseng, 13 parts of Chinese cassia tree, 18 parts of fructus alpiniae oxyphyllae, 15 parts of longan, raspberry 22
Part, 30 parts of Herba Epimedii, 20 parts of thizoma curculiginis, 17 parts of Hangzhoupro Morinda offcinalis How, 10 parts of fennel seeds, 20 parts of Chinese yam, 17 parts of semen allii tuberosi, 9 parts of Schisandra chinensis, vehicle
First sub 18 parts, 23 parts of Herba Cistanches, 20 parts of cynomorium songaricum, 11 parts of burnt cypress, 11 parts of rhizoma anemarrhenae, 11 parts of fructus amomi, 12 parts of Radix Angelicae Sinensis, 25 parts of English walnut, greatly
25 parts of jujube.
Preferably, the Semen Cuscutae is salt Semen Cuscutae；The fructus alpiniae oxyphyllae is salt fructus alpiniae oxyphyllae；The Herba Epimedii is suet
Oil Herba Epimedii；The thizoma curculiginis is wine thizoma curculiginis；The Hangzhoupro Morinda offcinalis How is salt Hangzhoupro Morinda offcinalis How；The semen allii tuberosi is to fry semen allii tuberosi；Institute
It is salt plantain seed to state plantain seed；The rhizoma anemarrhenae is salt rhizoma anemarrhenae；The fructus amomi is salt fructus amomi.
Wherein, pharmaceutical composition of the invention is to be by the medicinal powder of bulk pharmaceutical chemicals, the water of bulk pharmaceutical chemicals or extractive with organic solvent
Active constituent, in addition the preparation that acceptable auxiliary material or complementary ingredient are prepared in pharmacy.
Further, the preparation is oral preparation, and the preferred oral preparation is decoction, powder, tablet, capsule
Agent, granule, pill, oral solution, paste.
In the pharmaceutical composition of the present invention, medicinal flavor effect used is as follows：
Ginseng：Slightly warm in nature, sweet in flavor, slight bitter.It reinforces vital energy, veins takes off admittedly reinforces the spleen to benefit the lung, shengjin nourishing, tranquilize the mind and promote the intelligence；
Chinese yam：It is mild-natured, it is sweet in flavor.Tonifying spleen nourishing the stomach, engender liquid and benefic lung, the puckery essence of kidney tonifying；
Chinese cassia tree：It is pungent, sweet, big heat.With mends fire supporing yang, guiding fire to origin, eliminating cold to stop pain, warming meridian effect；
Fructus alpiniae oxyphyllae：It is acrid in flavour and warm in nature.Warm kidney, astringent sperm contracting urine, warm spleen, take the photograph saliva at antidiarrheal；
Raspberry：It is sweet, sour, temperature.Supplementing the kidney to control the nocturnal contracting urine, nourishes the liver to improve visual acuity；
Fennel seeds：It is acrid in flavour and warm in nature.Eliminating cold to stop pain, regulating qi-flowing for harmonizing stomach；
Longan：It is warm-natured, it is sweet in flavor.Tonifying heart and spleen, nourishing blood and tranquilization；
Fry semen allii tuberosi：It is warm-natured, it is acrid flavour, sweet.Warm filling liver kidney, establishing-Yang controlling nocturnal emission with astringent drugs.Priming downlink after salt system enhances the work that invigorates the kidney and stops nocturnal emission
With；
Schisandra chinensis：It is warm-natured, it is sour, sweet.Restrain astringent method, Mi Gu granule, kidney calming；
Salt plantain seed：It is cold in nature, sweet in flavor.Reducing fever and causing diuresis is treating stranguria, and phlegm is removed in excreting dampness antidiarrheal, improving eyesight.It is cold in nature partially gentle after salt system,
It is sweet in flavor, it is micro- salty.Liver and kidney benefiting, function of improving eyesight enhancing.It is mainly used for liver-fire flaming or wind-heat of liver channel；
Salt Semen Cuscutae：It is mild-natured, it is acrid flavour, sweet.It tonifies the liver and kidney, astringent sperm contracting urine, tocolysis, improving eyesight, antidiarrheal.Priming enters after salt system
Kidney enhances the role of tocolysis that invigorates the kidney and stops nocturnal emission；
Herba Cistanches：It is warm-natured, sweet in flavor, salty.Kidney-replenishing, benefiting essence-blood relax bowel；
Cynomorium songaricum：It is warm-natured, sweet in flavor.Kidney-replenishing, benefiting essence-blood, relax bowel；
Salt Hangzhoupro Morinda offcinalis How：Slightly warm in nature, it is sweet in flavor, pungent.Kidney-replenishing, strengthening the bones and muscles, wind-damp dispelling.Specially enter kidney channel after salt system, temperature without
It is dry, it based on tonifying the kidney and support yang, and acts on and mitigating, long term usage takes the disadvantage without impairment of yin more；
Jiao Bai：It is cold in nature, bitter.Heat-clearing and damp-drying drug, purging intense heat, except steaming, detoxification sore treatment.The property of bitter cold declines after processing；
Salt rhizoma anemarrhenae：It is cold in nature, it is bitter, sweet.Clearing heat-fire, nourishing Yin and moistening dryness.Priming enters kidney after salt system, and enhancing nourishing yin and lessening fire is made
With；
Salt fructus amomi：It is warm-natured, acrid flavour.Dampness elimination appetizing, warming spleen and stopping diarrha, regulating the flow of vital energy antiabortive.Priming downlink after salt system improves warm kidney
Cold dispelling curative effect；
Radix Angelicae Sinensis：Radix Angelicae Sinensis, it is warm-natured, it is acrid flavour, sweet.It enriches blood, invigorates blood circulation, menstruction regulating and pain relieving, moisturize laxation；
English walnut:It is warm-natured, it is sweet in flavor.Kidney tonifying, warm lung, ease constipation；
Suet oil Herba Epimedii：It is warm-natured, it is acrid flavour, sweet.Kidney-replenishing, strengthening the bones and muscles, wind-damp dispelling.Product can enhance warming kidney and enhancing yang
Effect；
Jujube：It is warm-natured, sweet in flavor.Tonifying middle-Jiao and Qi, nourishing blood and tranquilization；
Wine thizoma curculiginis：Property heat, acrid flavour.Kidney-replenishing, strengthening the bones and muscles, dispellieg cold and dampness.Enhance promoting blood circulation effect after wine system.
In pharmaceutical composition prescription of the present invention：The fruit of Chinese wolfberry, Semen Cuscutae are altogether monarch drug in a prescription, and tonifying kidney and benefiting sperm, beneficial the moon helps sun；It is aided with
Ministerial drug：Ginseng, Chinese yam are reinforced vital energy, and full of vitality, Chinese cassia tree mends fire supporing yang, guiding fire to origin, fructus alpiniae oxyphyllae, galangal, fennel seeds are made
Supporing yang controlling nocturnal emission with astringent drugs, warming channel and expelling cold, arillus longan kidney-nourishing is calmed the nerves, invigorating spleen and kidney, raspberry, suet oil Herba Epimedii warming kidney and enhancing yang, wine system
Thizoma curculiginis kidney-replenishing, strengthening the bones and muscles, salt Hangzhoupro Morinda offcinalis How amount to kidney-replenishing specially in entering kidney after salt toast, strengthening the bones and muscles, wind-damp dispelling, after salt system specially
Enter kidney channel, it is warm but not dry, to tonify the kidney and support yang；Assistant with Schisandra chinensis, raspberry, English walnut it is sandwich reach conditioning deficiency of yang symptom reinforce the kidney it is puckery
Essence；Using corrigent coke cypress heat-clearing and damp-drying drug, purging intense heat, except steaming, the property of bitter cold declines after processing, salt rhizoma anemarrhenae, clearing heat-fire, nourishing Yin and moistening dryness, salt
Priming enters kidney, enhancing nourishing yin and lessening fire effect after system, and plantain seed diuresis expels the heat-evil.All auxiliary material-saline tastes that drug is processed through salt are salty, salty
It is to make to enter kidney, makes the pharmacological property in entire prescription specially in entering kidney, and Chinese medicine has kind yang-tonifying person, must be in treating YANG within YIN, all medicines share, this
Invention pharmaceutical composition has with bowl spares rushes down, and advantageous in puckery, the compatible experiments of sun are helped in tonifying yin, is mainly used for impotence infertility, seminal emission
The diseases such as premature ejaculation.By differentiation of tcm rule, the diseases interpretation of the cause, onset and process of an illness category kidney essense inadequate natural endowment such as impotence infertility, premature ejaculation of passing out semen, negative and positive are biochemical
It is passive, tonifying kidney and benefiting sperm should be imposed, fills up vital essence, the secret method for taking the photograph Yuanyang, up to controlling the benefits of infertile.
The present invention also provides the preparation methods of aforementioned pharmaceutical compositions, it includes the following steps：
1) each raw material is weighed by weight ratio, beats powder or adds water or organic solvent extraction；
2) medicinal powder, water or extractive with organic solvent of bulk pharmaceutical chemicals are taken, and in pharmacy acceptable auxiliary material or it is complementary at
Divide and is prepared into preparation.
The present invention also provides aforementioned pharmaceutical compositions in the purposes in preparing infertile drug.
Wherein, the drug is treatment hypoimmunity, hypogona dism, impotence premature ejaculation, infertile, hands and feet being not warm
And/or the drug of soreness and weakness of waist and knees pain.
The pharmaceutical composition of the present invention, compatibility is precise and appropriate between drug, and each flavour of a drug complement each other, and there is bowl spares to have and rush down, have in puckery
The compatible experiments of sun are helped in profit, tonifying yin, are mainly used for the symptoms such as impotence infertility, the premature ejaculation of passing out semen caused by treating kidney-yang deficiency, and in side
Raw materials used medicine is integration of drinking and medicinal herbs medicinal material, is had no toxic and side effect to human body, and can be taken for a long time.
Obviously, the above according to the present invention is not being departed from according to the ordinary technical knowledge and customary means of this field
Under the premise of the above-mentioned basic fundamental thought of the present invention, the modification, replacement or change of other diversified forms can also be made.
The specific implementation mode of form by the following examples remakes further specifically the above of the present invention
It is bright.But the range that this should not be interpreted as to the above-mentioned theme of the present invention is only limitted to example below.It is all to be based on the above of the present invention
The technology realized all belongs to the scope of the present invention.
Specific implementation mode
The preparation of 1 pharmaceutical composition soft extract of the present invention of embodiment
1 prescription
Ginseng 15g, longan 15g, fruit of Chinese wolfberry 25g fry semen allii tuberosi 17g, Schisandra chinensis 9g, salt plantain seed 18g, salt Tu Silk
Sub- 20g, raspberry 22g, salt fructus alpiniae oxyphyllae 18g, Herba Cistanches 23g, cynomorium songaricum 20g, salt Hangzhoupro Morinda offcinalis How 17g, burnt cypress 11g, Chinese cassia tree
13g, salt rhizoma anemarrhenae 11g, salt fructus amomi 11g, Radix Angelicae Sinensis 12g, English walnut 25g, suet oil Herba Epimedii 30g, jujube 25g, wine system are celestial
Thatch 20g, fennel seeds 10g, Chinese yam 20g.
2 preparation methods
1) prepared by clear cream：The bulk pharmaceutical chemicals of recipe quantity are taken, the water that 10 times of amounts are added decocts, and slightly boiling is kept to extract 30~40 points
Clock, second of 8 times of amount water, decocts, 30 minutes, decocts 2 times altogether, merge decoction liquor, filtering, concentration filtrate to relative density 1.20
~1.35 to get clear cream；
2) cream is received：By weight 1:1 to clear cream be added refined honey receive cream to get.
The preparation of 2 pharmaceutical composition decoction of the present invention of embodiment
10~15 parts of fennel seeds, 20~40 parts of Chinese yam
Ginseng 10g, longan 10g, fruit of Chinese wolfberry 20g are taken, semen allii tuberosi 15g, Schisandra chinensis 7g, salt plantain seed 15g, salt Tu are fried
Silk 15g, raspberry 15g, salt fructus alpiniae oxyphyllae 15g, Herba Cistanches 15g, cynomorium songaricum 15g, salt Hangzhoupro Morinda offcinalis How 15g, burnt cypress 7g, Chinese cassia tree
10g, salt rhizoma anemarrhenae 7g, salt fructus amomi 7g, Radix Angelicae Sinensis 10g, English walnut 20g, suet oil Herba Epimedii 20g, jujube 20g, wine thizoma curculiginis
15g, fennel seeds 10g, Chinese yam 40g soak decoction, merge extracting solution, filtering to get.
The preparation of 3 medicinal composition powders of the present invention of embodiment
Ginseng 20g, longan 20g, fruit of Chinese wolfberry 30g are taken, semen allii tuberosi 20g, Schisandra chinensis 10g, salt plantain seed 20g, salt system are fried
Dodder 25g, raspberry 30g, salt fructus alpiniae oxyphyllae 20g, Herba Cistanches 30g, cynomorium songaricum 25g, salt Hangzhoupro Morinda offcinalis How 20g, burnt cypress 15g, meat
Osmanthus 15g, salt rhizoma anemarrhenae 15g, salt fructus amomi 15g, Radix Angelicae Sinensis 15g, English walnut 30g, the excessive sheep of suet oil system close 40g, jujube 30g, wine system
Thizoma curculiginis 25g, fennel seeds 15g, Chinese yam 20g, be added auxiliary material, crush, sieving to get.
The preparation of 4 medicinal composition tablets of the present invention of embodiment
Ginseng 13g, longan 13g, fruit of Chinese wolfberry 22g are taken, semen allii tuberosi 16g, Schisandra chinensis 8g, salt plantain seed 17g, salt Tu are fried
Silk 17g, raspberry 18g, salt fructus alpiniae oxyphyllae 17g, Herba Cistanches 19g, cynomorium songaricum 18g, salt Hangzhoupro Morinda offcinalis How 16g, burnt cypress 9g, Chinese cassia tree
11g, salt rhizoma anemarrhenae 9g, salt fructus amomi 9g, Radix Angelicae Sinensis 11g, English walnut 23g, the excessive sheep of suet oil system close 25g, jujube 22g, wine thizoma curculiginis
17g, fennel seeds 12g, Chinese yam 30g add water to cook extraction, are condensed into medicinal extract, be added starch granulation, whole grain, tabletting to get.
The preparation of 5 medicament composition capsule agent of the present invention of embodiment
Ginseng 18g, longan 18g, fruit of Chinese wolfberry 27g are taken, semen allii tuberosi 19g, Schisandra chinensis 9g, salt plantain seed 19g, salt Tu are fried
Silk 23g, raspberry 26g, salt fructus alpiniae oxyphyllae 19g, Herba Cistanches 27g, cynomorium songaricum 22g, salt Hangzhoupro Morinda offcinalis How 19g, burnt cypress 13g, Chinese cassia tree
14g, salt rhizoma anemarrhenae 13g, salt fructus amomi 13g, Radix Angelicae Sinensis 14g, English walnut 28g, the excessive sheep of suet oil system close 35g, jujube 27g, wine system celestial being
Thatch 22g, fennel seeds 15g, Chinese yam 20g add water to cook extraction, are condensed into medicinal extract, be added auxiliary material, mixing, packing to get.
The preparation of 6 medicament composition granule agent of the present invention of embodiment
Ginseng 15g, longan 15g, fruit of Chinese wolfberry 25g are taken, semen allii tuberosi 17g, Schisandra chinensis 9g, salt plantain seed 18g, salt Tu are fried
Silk 20g, raspberry 22g, salt fructus alpiniae oxyphyllae 18g, Herba Cistanches 23g, cynomorium songaricum 20g, salt Hangzhoupro Morinda offcinalis How 17g, burnt cypress 11g, Chinese cassia tree
13g, salt rhizoma anemarrhenae 11g, salt fructus amomi 11g, Radix Angelicae Sinensis 12g, English walnut 25g, the excessive sheep of suet oil system close 30g, jujube 25g, wine system celestial being
Auxiliary material is added in thatch 20g, fennel seeds 15g, Chinese yam 40g, crushes, and is sieved, and pelletizes, dry, whole grain to get.
The preparation of 7 pharmaceutical composition honeyed bolus of the present invention of embodiment
Ginseng 15g, longan 15g, fruit of Chinese wolfberry 25g are taken, semen allii tuberosi 17g, Schisandra chinensis 9g, salt plantain seed 18g, salt Tu are fried
Silk 20g, raspberry 22g, salt fructus alpiniae oxyphyllae 18g, Herba Cistanches 23g, cynomorium songaricum 20g, salt Hangzhoupro Morinda offcinalis How 17g, burnt cypress 11g, Chinese cassia tree
13g, salt rhizoma anemarrhenae 11g, salt fructus amomi 11g, Radix Angelicae Sinensis 12g, English walnut 25g, the excessive sheep of suet oil system close 30g, jujube 25g, wine system celestial being
Thatch 20g, fennel seeds 15g, Chinese yam 30g beat powder, sieving, are added honey, pill, it is dry to get.
The preparation of 8 drug composition oral liquid of the present invention of embodiment
Ginseng 15g, longan 15g, fruit of Chinese wolfberry 25g are taken, semen allii tuberosi 17g, Schisandra chinensis 9g, salt plantain seed 18g, salt Tu are fried
Silk 20g, raspberry 22g, salt fructus alpiniae oxyphyllae 18g, Herba Cistanches 23g, cynomorium songaricum 20g, salt Hangzhoupro Morinda offcinalis How 17g, burnt cypress 11g, Chinese cassia tree
13g, salt rhizoma anemarrhenae 11g, salt fructus amomi 11g, Radix Angelicae Sinensis 12g, English walnut 25g, the excessive sheep of suet oil system close 30g, jujube 25g, wine system celestial being
Thatch 20g, fennel seeds 15g, Chinese yam 40g soak decoction, merging filtrate, concentration, embedding, sterilizing to get.
Beneficial effects of the present invention are proved below by way of specific clinical test：
Infertile clinical efficacy caused by 1 medicine composite for curing kidney-yang deficiency of the present invention of test example
1 experiment material
1) experimental drug：The pharmaceutical composition of the present invention, is prepared by embodiment 1；
2) control drug：Wuzi yanzong pills (water-honeyed pill)
3) patient data：The infertile male of kidney-yang deficiency, totally 44.
2 test methods
1) diagnostic criteria：By kidney deficiency infertility, frigidity standard screening, clinical diagnosis is mainly shown as the insufficiency of both the spleen and the kindey, male sexuality
It does not lift, impotence premature ejaculation, the symptoms such as waist and knee crymodynia.
2) curative effect judges：
It is clearly better：Clinical symptoms, sign disappear substantially；
It improves：Clinical symptoms, sign improve；
In vain：Clinical symptoms, sign nothing are substantially change.
3) it is grouped
44 patient's stochastic averaginas are divided into two groups, every group 22.
4) medication
The each 6g of wuzi yanzong pills group, 2 times a day.
The soft extract of the preparation gained of the embodiment of the present invention 1, each 10g, 3 times a day.
4) experimental result
Test result shows that total effective rate infertile caused by medicine composite for curing kidney-yang deficiency of the invention is
59.1%, illustrate the symptoms such as impotence infertility, the premature ejaculation of passing out semen that pharmaceutical composition of the present invention can be obviously improved caused by kidney-yang deficiency, and excellent
In existing drug wuzi yanzong pills.
The classical case of 2 medicine composite for curing kidney-yang deficiency of the present invention of test example
Classical case 1：
Wang certain, man 42 years old, often feels soreness of waist and knee, and aversion to cold and cold limbs is apathetic, and impotence, lifts without heavily fortified point, essence
Thin chilly, penis is not warm, and complexion Anhui is white, leads to impotence for the deficiency of yang through Chinese medical discrimination, gets married 5 years and be difficult to become pregnant, take the present invention
Composition (embodiment 1 is prepared) 3 months chambers take an evident turn for the better, and adhere to taking 6 months, and madam's love is pregnant, cuts open the belly after 9 months
Produce one 6.8 jin of girl babys.
Classical case 2：
Week certain, 30 years old, 4 years s.m.ps of getting married had hand Masturbation customs, after marriage sexual overstrain to cause kidney yang impaired before marriage, and impotence is early
It rushes down, cold sperm is sterile or even infertile.Diuresis, pale tongue with white fur, the thin and delicate inability of slow and sunken pulse.It is kidney-yang deficiency through Chinese medical discrimination, takes this hair
Bright 2 weeks symptoms of composition (embodiment 1 is prepared) are improved, and adhere to being pregnant after taking 10 weeks.
To sum up, pharmaceutical composition of the invention, compatibility is precise and appropriate between drug, and each flavour of a drug complement each other, and there is bowl spares to have and rush down, puckery
In it is advantageous, the compatible experiments of sun are helped in tonifying yin, can be obviously improved the symptoms such as impotence infertility, the premature ejaculation of passing out semen caused by kidney-yang deficiency, and just
In raw materials used medicine be integration of drinking and medicinal herbs medicinal material, have no toxic and side effect to human body, can take for a long time.
Claims (10)
1. a kind for the treatment of infertile pharmaceutical composition, it is characterised in that：It is prepared by the bulk pharmaceutical chemicals that following weight matches
At preparation：
20~30 parts of the fruit of Chinese wolfberry, 15~25 parts of , dodders, 10~20 parts of ginseng, 10~15 parts of Chinese cassia tree, 15~20 parts of fructus alpiniae oxyphyllae, dragon
10~20 parts of eye, 15~30 parts of raspberry, 20~40 parts of Herba Epimedii, 15~25 parts of thizoma curculiginis, 15~20 parts of Hangzhoupro Morinda offcinalis How, fennel seeds 10
~15 parts, 20~40 parts of Chinese yam.
2. pharmaceutical composition according to claim 1, it is characterised in that：It is the bulk pharmaceutical chemicals system for including following weight proportioning
It is standby at preparation：
25 parts of the fruit of Chinese wolfberry, 20 parts of , dodders, 15 parts of ginseng, 13 parts of Chinese cassia tree, 18 parts of fructus alpiniae oxyphyllae, 15 parts of longan, 22 parts of raspberry are excessive
30 parts of the sheep leaves of pulse plants, 20 parts of thizoma curculiginis, 10 parts of fennel seeds, 17 parts of Hangzhoupro Morinda offcinalis How, 20 parts of Chinese yam.
3. pharmaceutical composition according to claim 1, it is characterised in that：It also includes the bulk pharmaceutical chemicals of following weight proportioning：
15~20 parts of semen allii tuberosi, 7~10 parts of Schisandra chinensis, 15~20 parts of plantain seed, 15~30 parts of Herba Cistanches, 15~25 parts of cynomorium songaricum,
7~15 parts of burnt cypress, 7~15 parts of rhizoma anemarrhenae, 7~15 parts of fructus amomi, 10~15 parts of Radix Angelicae Sinensis, 20~30 parts of English walnut, 20~30 parts of jujube.
4. according to claim 1-3 any one of them pharmaceutical compositions, it is characterised in that：It is the original matched by following weight
The preparation that material medicine is prepared into：
25 parts of the fruit of Chinese wolfberry, 20 parts of , dodders, 15 parts of ginseng, 13 parts of Chinese cassia tree, 18 parts of fructus alpiniae oxyphyllae, 15 parts of longan, 22 parts of raspberry are excessive
30 parts of the sheep leaves of pulse plants, 20 parts of thizoma curculiginis, 17 parts of Hangzhoupro Morinda offcinalis How, 10 parts of fennel seeds, 20 parts of Chinese yam, 17 parts of semen allii tuberosi, 9 parts of Schisandra chinensis, plantain seed
18 parts, 23 parts of Herba Cistanches, 20 parts of cynomorium songaricum, 11 parts of burnt cypress, 11 parts of rhizoma anemarrhenae, 11 parts of fructus amomi, 12 parts of Radix Angelicae Sinensis, 25 parts of English walnut, jujube 25
Part.
5. according to Claims 1 to 4 any one of them pharmaceutical composition, it is characterised in that：The Semen Cuscutae is salt Tu
Son；The fructus alpiniae oxyphyllae is salt fructus alpiniae oxyphyllae；The Herba Epimedii is suet oil Herba Epimedii；The thizoma curculiginis is wine thizoma curculiginis；It is described
Hangzhoupro Morinda offcinalis How is salt Hangzhoupro Morinda offcinalis How；The semen allii tuberosi is to fry semen allii tuberosi；The plantain seed is salt plantain seed；The rhizoma anemarrhenae is salt system
Rhizoma anemarrhenae；The fructus amomi is salt fructus amomi.
6. according to Claims 1 to 5 any one of them pharmaceutical composition, it is characterised in that：It is medicinal powder by bulk pharmaceutical chemicals, original
Expect that the water of medicine or extractive with organic solvent are active constituent, and in pharmacy acceptable auxiliary material or complementary ingredient prepare and
At preparation.
7. according to claim 1~6 any one of them pharmaceutical composition, it is characterised in that：The preparation is oral preparation, excellent
The oral preparation of choosing is decoction, powder, tablet, capsule, granule, pill, oral solution, paste.
8. the preparation method of claim 1~7 any one of them pharmaceutical composition, it is characterised in that：It includes the following steps：
1) each raw material is weighed by weight ratio, beats powder or adds water or organic solvent extraction；
2) medicinal powder, water or extractive with organic solvent of bulk pharmaceutical chemicals are taken, in addition acceptable auxiliary material or complementary ingredient system in pharmacy
For at preparation.
9. purposes of claim 1~7 any one of them pharmaceutical composition in preparing infertile drug.
10. purposes according to any one of claims 10, it is characterised in that：The drug is treatment hypoimmunity, hypogona dism, sun
Impotence premature ejaculation, infertile, hands and feet being not warm and/or soreness and weakness of waist and knees pain drug.
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| CN201810805650.1A CN108619441A (en) | 2018-07-20 | 2018-07-20 | It is a kind of to treat infertile pharmaceutical composition and its preparation method and application |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810805650.1A CN108619441A (en) | 2018-07-20 | 2018-07-20 | It is a kind of to treat infertile pharmaceutical composition and its preparation method and application |
Publications (1)
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Family
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN110859918A (en) * | 2019-12-09 | 2020-03-06 | 华中科技大学同济医学院附属协和医院 | Medicine and food homologous prescription for treating kidney-yang deficiency and preparation method thereof |
| CN112089807A (en) * | 2020-10-20 | 2020-12-18 | 龙步明 | A Chinese medicinal preparation for treating sexual hypofunction of middle-aged and elderly people |
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| CN1858182A (en) * | 2006-03-10 | 2006-11-08 | 顾朝清 | Yang Strengthening wine |
| CN101524461A (en) * | 2009-04-07 | 2009-09-09 | 朱亚夫 | Pure traditional Chinese medicine composition for treating male infertility and pure traditional Chinese medicine preparation prepared thereby |
| CN107050247A (en) * | 2017-01-10 | 2017-08-18 | 崔悦 | Chinese yam kidney-Yang ball |
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| CN1858182A (en) * | 2006-03-10 | 2006-11-08 | 顾朝清 | Yang Strengthening wine |
| CN101524461A (en) * | 2009-04-07 | 2009-09-09 | 朱亚夫 | Pure traditional Chinese medicine composition for treating male infertility and pure traditional Chinese medicine preparation prepared thereby |
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| CN110859918A (en) * | 2019-12-09 | 2020-03-06 | 华中科技大学同济医学院附属协和医院 | Medicine and food homologous prescription for treating kidney-yang deficiency and preparation method thereof |
| CN112089807A (en) * | 2020-10-20 | 2020-12-18 | 龙步明 | A Chinese medicinal preparation for treating sexual hypofunction of middle-aged and elderly people |
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Application publication date: 20181009 |