CN108606935A - A kind of skin care item preparation method containing transdermal small peptide - Google Patents
A kind of skin care item preparation method containing transdermal small peptide Download PDFInfo
- Publication number
- CN108606935A CN108606935A CN201810509799.5A CN201810509799A CN108606935A CN 108606935 A CN108606935 A CN 108606935A CN 201810509799 A CN201810509799 A CN 201810509799A CN 108606935 A CN108606935 A CN 108606935A
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- Prior art keywords
- small peptide
- skin care
- care item
- transdermal small
- method containing
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
- A61K8/553—Phospholipids, e.g. lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The present invention provides a kind of skin care item preparation method containing transdermal small peptide, includes the following steps：Raw material is chosen to be prepared；Contrast experiment, compared with prior art, the present invention have following advantageous effect：The skin care item can be applied to the facial mask essence in skin care item, Essence, lotion, the addition of maintenance skin effect object of cream, because the present invention is added to transdermal small peptide, hydrolecithin, the chlorella growth factor and methyl propanediol, which improves human epidermal growth factor the effect of effective absorptivity of skin care item is to reach maintenance.
Description
Technical field
The present invention is a kind of skin care item preparation method containing transdermal small peptide, belongs to cosmetic technical field.
Background technology
Epithelical cell growth factor also known as people's oligopeptides are a kind of active material in human body, the work being made of 53 amino
Property polypeptide, by stimulation epidermal growth factor receptor tyrosine phosphorylation, reach repairing hyperplasia skin surface cell, according to
It says and excellent curative effect is possessed to injured, impaired epidermis skin.Its maximum feature is can to promote the Proliferation, Differentiation of cell, to
Aging and dead cell are replaced with newborn cell.
Use the product of human epidermal growth factor (EGF) very more on the market at present, but oligopeptides biological configuration and molecule
The limitation of amount so that the effective percentage for entering skin is not satisfactory, is badly in need of a kind of solving for the reparation raw material of skin care item now
Original technical problem.
Invention content
In view of the deficienciess of the prior art, it is an object of the present invention to provide a kind of skin care item preparation side containing transdermal small peptide
Method, to solve the problems mentioned in the above background technology.
To achieve the goals above, the present invention is to realize by the following technical solutions：It is a kind of containing transdermal small peptide
Skin care item preparation method, it is characterised in that：Include the following steps：
Raw material is chosen to be prepared；
Contrast experiment.
Further, choose raw material prepared the specific steps are：Choose raw material prepared the specific steps are：First
Weigh 1 part of transdermal small peptide, 1 part of hydrolecithin, 2 parts of the chlorella growth factor, 1.5 parts of methyl propanediol after weighing, first takes
1.5 parts with methyl propanediol of 2 parts of the chlorella growth factor mixes, and is stirred evenly 1 part of transdermal small peptide after mixing, is added, so
After add hydrolecithin, form mixture, mixture be placed on homogeneous 5 minutes in homogenizer, that is, prepares completion.
Further, the chlorella growth factor is green algal extract.
Further, methyl propanediol is to be used as solvent herein, for disperseing transdermal small peptide.
Further, hydrolecithin is used to be wrapped in the outer layer of transdermal small peptide and the chlorella growth factor so that transdermal short
Peptide can be quickly absorbed by the skin with the chlorella growth factor.
Further, the contrast experiment the specific steps are：It is substrate and skin care item of the present invention to choose blank Essence
Variation in one month weekly compares.
Beneficial effects of the present invention：A kind of skin care item preparation method containing transdermal small peptide of the present invention, which can
Applied to facial mask essence, Essence, lotion, the addition of maintenance skin effect object of cream, because the present invention be added to it is transdermal short
Peptide, hydrolecithin, the chlorella growth factor and methyl propanediol, the design improve human epidermal growth factor in skin care item
The effect of effective absorptivity is to reach maintenance.
Specific implementation mode
To make the technical means, the creative features, the aims and the efficiencies achieved by the present invention be easy to understand, with reference to
Specific implementation mode, the present invention is further explained.
The present invention provides a kind of technical solution：A kind of skin care item preparation method containing transdermal small peptide, includes the following steps：
Raw material is chosen to be prepared；
Contrast experiment.
Choose raw material prepared the specific steps are：Choose raw material prepared the specific steps are：It first weighs transdermal
1 part of small peptide, 1 part of hydrolecithin, 2 parts of the chlorella growth factor, 1.5 parts of methyl propanediol after weighing, first take chlorella growth
1.5 parts with methyl propanediol of 2 parts of the factor mixes, and stirs evenly 1 part of transdermal small peptide after mixing, is added, then adds
Hydrolecithin forms mixture, mixture is placed on homogeneous 5 minutes in homogenizer, that is, prepares completion.
The chlorella growth factor is green algal extract.
Methyl propanediol is to be used as solvent herein, for disperseing transdermal small peptide.
Hydrolecithin is used to be wrapped in the outer layer of transdermal small peptide and the chlorella growth factor so that transdermal small peptide is given birth to green alga
The long factor can be quickly absorbed by the skin.
Contrast experiment the specific steps are：Choose blank Essence be substrate and skin care item of the present invention in one month weekly
Variation compare.
As an embodiment of the present invention：Raw material can be applied to the facial mask essence in skin care item, Essence, lotion,
The addition of maintenance skin effect object of cream, for addition more of the invention whether the effect of property, change be divided into two groups of experiments, with blank
Essence is substrate, and one group is simple EGF1 parts of addition, and another group is the Essence for adding the present invention, is applied on the inside of hand daily
It smears, once in the morning and once at night, the skin degree of improvement after observing 7-28 days is fed back to score, and for score by 0-5 points, 0 point is that skin quality is improvement,
5 points for change degree it is most apparent, thus table 1 can be found, add the present invention essence liquid be fed back to skin quality improve degree it is preferable.
Table 1 is the contrast table that blank Essence is substrate and raw material of the present invention
| Number of days | EGF Essences | Add the Essence of the present invention |
| 7 | 2 | 3 |
| 14 | 2.5 | 3.5 |
| 21 | 3 | 4 |
| 28 | 3.5 | 4.5 |
The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention, for this field skill
For art personnel, it is clear that invention is not limited to the details of the above exemplary embodiments, and without departing substantially from the present invention spirit or
In the case of essential characteristic, the present invention can be realized in other specific forms.Therefore, in all respects, should all incite somebody to action
Embodiment regards exemplary as, and is non-limiting, the scope of the present invention by appended claims rather than on state
Bright restriction, it is intended that including all changes that come within the meaning and range of equivalency of the claims in the present invention
It is interior.
In addition, it should be understood that although this specification is described in terms of embodiments, but not each embodiment is only wrapped
Containing an independent technical solution, this description of the specification is merely for the sake of clarity, and those skilled in the art should
It considers the specification as a whole, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art
The other embodiment being appreciated that.
Claims (6)
1. a kind of skin care item preparation method containing transdermal small peptide, it is characterised in that：Include the following steps：
Raw material is chosen to be prepared；
Contrast experiment.
2. a kind of skin care item preparation method containing transdermal small peptide according to claim 1, it is characterised in that：Choose raw material
Prepared the specific steps are：First weigh 1 part of transdermal small peptide, 1 part of hydrolecithin, 2 parts of the chlorella growth factor, methyl-prop two
1.5 parts of alcohol after weighing, first takes 2 parts of the chlorella growth factor to be mixed for 1.5 parts with methyl propanediol, after mixing, is added
1 part of transdermal small peptide stirs evenly, and then adds hydrolecithin, forms mixture, mixture is placed in homogenizer
Matter 5 minutes, that is, prepare completion.
3. a kind of skin care item preparation method containing transdermal small peptide according to claim 2, it is characterised in that：Chlorella growth
The factor is green algal extract.
4. a kind of skin care item preparation method containing transdermal small peptide according to claim 2, it is characterised in that：Methyl-prop two
Alcohol is to be used as solvent herein, for disperseing transdermal small peptide.
5. a kind of skin care item preparation method containing transdermal small peptide according to claim 2, it is characterised in that：Hydrogenate lecithin
Fat is used to be wrapped in the outer layer of transdermal small peptide and the chlorella growth factor so that transdermal small peptide can be quickly by skin with the chlorella growth factor
Skin absorbs.
6. a kind of skin care item preparation method containing transdermal small peptide according to claim 1, it is characterised in that：The comparison
Experiment the specific steps are：It is that the variation of control group and skin care item of the present invention in one month weekly carries out to choose blank Essence
Comparison.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810509799.5A CN108606935A (en) | 2018-05-24 | 2018-05-24 | A kind of skin care item preparation method containing transdermal small peptide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810509799.5A CN108606935A (en) | 2018-05-24 | 2018-05-24 | A kind of skin care item preparation method containing transdermal small peptide |
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| Publication Number | Publication Date |
|---|---|
| CN108606935A true CN108606935A (en) | 2018-10-02 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201810509799.5A Pending CN108606935A (en) | 2018-05-24 | 2018-05-24 | A kind of skin care item preparation method containing transdermal small peptide |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110201147A (en) * | 2019-05-23 | 2019-09-06 | 中山市粤美医疗生物科技有限公司 | A kind of composition and preparation method thereof comprising peptide |
| CN110269817A (en) * | 2019-03-19 | 2019-09-24 | 广州市拉凯尔干细胞研究所 | A kind of composite skin care product preparation method containing camellia flower extract |
| CN110835587A (en) * | 2019-11-20 | 2020-02-25 | 茗汲(浙江)生物科技有限公司 | White tea antibacterial handmade soap and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007035474A2 (en) * | 2005-09-15 | 2007-03-29 | Novomed Technologies, Inc. (Shanghai) | Transdermal delivery peptides and method of use thereof |
| CN102210853A (en) * | 2010-04-01 | 2011-10-12 | 孙民富 | Method for preparing liposome containing EGFs (Epidermal Growth Factors) and transdermal short peptide fusion proteins, for controlling diabetic foot gangrene |
| CN102579303A (en) * | 2012-03-26 | 2012-07-18 | 海南海之润生物工程有限公司 | Green alga liposome and preparation method and application thereof |
-
2018
- 2018-05-24 CN CN201810509799.5A patent/CN108606935A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007035474A2 (en) * | 2005-09-15 | 2007-03-29 | Novomed Technologies, Inc. (Shanghai) | Transdermal delivery peptides and method of use thereof |
| CN102210853A (en) * | 2010-04-01 | 2011-10-12 | 孙民富 | Method for preparing liposome containing EGFs (Epidermal Growth Factors) and transdermal short peptide fusion proteins, for controlling diabetic foot gangrene |
| CN102579303A (en) * | 2012-03-26 | 2012-07-18 | 海南海之润生物工程有限公司 | Green alga liposome and preparation method and application thereof |
Non-Patent Citations (1)
| Title |
|---|
| 安红编著: "《磷脂化学及应用技术》", 30 June 2006, 中国计量出版社 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110269817A (en) * | 2019-03-19 | 2019-09-24 | 广州市拉凯尔干细胞研究所 | A kind of composite skin care product preparation method containing camellia flower extract |
| CN110201147A (en) * | 2019-05-23 | 2019-09-06 | 中山市粤美医疗生物科技有限公司 | A kind of composition and preparation method thereof comprising peptide |
| CN110835587A (en) * | 2019-11-20 | 2020-02-25 | 茗汲(浙江)生物科技有限公司 | White tea antibacterial handmade soap and preparation method thereof |
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