CN108603188A - 在细胞培养物中产生病毒 - Google Patents

在细胞培养物中产生病毒 Download PDF

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Publication number
CN108603188A
CN108603188A CN201680079158.XA CN201680079158A CN108603188A CN 108603188 A CN108603188 A CN 108603188A CN 201680079158 A CN201680079158 A CN 201680079158A CN 108603188 A CN108603188 A CN 108603188A
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Prior art keywords
virus
cells
cell
genetic modification
population
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Pending
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CN201680079158.XA
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English (en)
Chinese (zh)
Inventor
A·比恩
J·W·洛温塔尔
L·F·马拉佛-奥特佳
R·A·特里普
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Commonwealth Scientific and Industrial Research Organization CSIRO
University of Georgia
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Commonwealth Scientific and Industrial Research Organization CSIRO
University of Georgia
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Priority claimed from AU2015904851A external-priority patent/AU2015904851A0/en
Application filed by Commonwealth Scientific and Industrial Research Organization CSIRO, University of Georgia filed Critical Commonwealth Scientific and Industrial Research Organization CSIRO
Publication of CN108603188A publication Critical patent/CN108603188A/zh
Pending legal-status Critical Current

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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/02—Recovery or purification
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A61K39/17—Newcastle disease virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2760/16051—Methods of production or purification of viral material
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    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16051—Methods of production or purification of viral material
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    • C—CHEMISTRY; METALLURGY
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    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
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    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16151—Methods of production or purification of viral material
    • C—CHEMISTRY; METALLURGY
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    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16151—Methods of production or purification of viral material
    • C12N2760/16152—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16211—Influenzavirus B, i.e. influenza B virus
    • C12N2760/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16311—Influenzavirus C, i.e. influenza C virus
    • C12N2760/16334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18211—Henipavirus, e.g. hendra virus
    • C12N2760/18251—Methods of production or purification of viral material

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201680079158.XA 2015-11-24 2016-11-23 在细胞培养物中产生病毒 Pending CN108603188A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2015904851A AU2015904851A0 (en) 2015-11-24 Production of viruses in cell culture
AU2015904851 2015-11-24
PCT/AU2016/051147 WO2017088018A1 (en) 2015-11-24 2016-11-23 Production of viruses in cell culture

Publications (1)

Publication Number Publication Date
CN108603188A true CN108603188A (zh) 2018-09-28

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CN201680079158.XA Pending CN108603188A (zh) 2015-11-24 2016-11-23 在细胞培养物中产生病毒

Country Status (10)

Country Link
US (4) US11174466B2 (https=)
EP (1) EP3380611A4 (https=)
JP (2) JP7189017B2 (https=)
KR (1) KR20180081615A (https=)
CN (1) CN108603188A (https=)
AU (2) AU2016361455A1 (https=)
BR (1) BR112018010499A8 (https=)
CA (2) CA3247290A1 (https=)
MX (2) MX387420B (https=)
WO (1) WO2017088018A1 (https=)

Cited By (3)

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Publication number Priority date Publication date Assignee Title
CN110129281A (zh) * 2019-05-15 2019-08-16 成都天邦生物制品有限公司 一种使用悬浮细胞培养新城疫病毒的方法及应用
CN114774418A (zh) * 2022-04-19 2022-07-22 深圳市人民医院 shRNA分子及其在敲低TM9SF2基因表达中的应用
CN116656628A (zh) * 2023-07-31 2023-08-29 深圳市卫光生物制品股份有限公司 一种痘病毒载体疫苗的制备方法

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MX387420B (es) * 2015-11-24 2025-03-18 Commw Scient Ind Res Org Producción de virus en cultivos celulares.
EP3380616A4 (en) 2015-11-24 2019-11-06 Commonwealth Scientific and Industrial Research Organisation MANUFACTURE OF VIRUSES IN BIRDS
US11845989B2 (en) 2019-01-23 2023-12-19 Regeneron Pharmaceuticals, Inc. Treatment of ophthalmic conditions with angiopoietin-like 7 (ANGPTL7) inhibitors
MX2021008797A (es) 2019-01-23 2022-01-31 Regeneron Pharma Tratamiento de afecciones oftalmicas con inhibidores de proteinas relacionadas a angiopoyetina 7 (angptl7).
US11865134B2 (en) 2021-02-26 2024-01-09 Regeneron Pharmaceuticals, Inc. Treatment of inflammation with glucocorticoids and angiopoietin-like 7 (ANGPTL7) inhibitors
KR102898506B1 (ko) * 2021-04-30 2025-12-10 서울대학교산학협력단 바이러스 백신 생산용 조류 세포 제조용 조성물 및 바이러스 저항성 조류 세포 제조용 조성물

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110129281A (zh) * 2019-05-15 2019-08-16 成都天邦生物制品有限公司 一种使用悬浮细胞培养新城疫病毒的方法及应用
CN114774418A (zh) * 2022-04-19 2022-07-22 深圳市人民医院 shRNA分子及其在敲低TM9SF2基因表达中的应用
CN114774418B (zh) * 2022-04-19 2023-11-14 深圳市人民医院 shRNA分子及其在敲低TM9SF2基因表达中的应用
CN116656628A (zh) * 2023-07-31 2023-08-29 深圳市卫光生物制品股份有限公司 一种痘病毒载体疫苗的制备方法

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US11174466B2 (en) 2021-11-16
US20190322989A1 (en) 2019-10-24
AU2016361455A1 (en) 2018-06-21
BR112018010499A2 (en) 2018-11-13
CA3247290A1 (en) 2025-07-09
CA3005989C (en) 2025-11-18
EP3380611A4 (en) 2020-02-12
US20250011731A1 (en) 2025-01-09
JP2019500860A (ja) 2019-01-17
CA3005989A1 (en) 2017-06-01
BR112018010499A8 (pt) 2019-02-26
KR20180081615A (ko) 2018-07-16
MX2021009554A (es) 2021-09-08
US10626379B2 (en) 2020-04-21
US20180340153A1 (en) 2018-11-29
US20220106574A1 (en) 2022-04-07
JP7189017B2 (ja) 2022-12-13
US12054750B2 (en) 2024-08-06
JP2023014322A (ja) 2023-01-26
EP3380611A1 (en) 2018-10-03
MX2018006373A (es) 2018-11-09
WO2017088018A1 (en) 2017-06-01
AU2023200556A1 (en) 2023-03-02
MX387420B (es) 2025-03-18

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