CN1085789A - Honeysuckle flower liquid for treating comedo - Google Patents
Honeysuckle flower liquid for treating comedo Download PDFInfo
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- CN1085789A CN1085789A CN 93107488 CN93107488A CN1085789A CN 1085789 A CN1085789 A CN 1085789A CN 93107488 CN93107488 CN 93107488 CN 93107488 A CN93107488 A CN 93107488A CN 1085789 A CN1085789 A CN 1085789A
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Abstract
The present invention relates to a kind of be main component with the Flos Lonicerae, cure mainly the dermopathic Chinese medicinal liquid of acne.This medicinal liquid mainly is made up of the extracting solution of following material: 20～30 parts of Flos Loniceraes, 2.5～7.5 parts of Fructus Gardeniaes, 3.75～6.25 parts of Herba Taraxacis, each 2～3 parts of Cortex Dictamni, Fructus Cnidii, Herba Lycopi, the Radix Angelicae Dahuricae, Herba Asari, Semen Benincasae, Rhizoma Atractylodis and Rhizoma Cimicifugaes.Above-mentioned substance is mixed the back use steam distillation, again distillate is left standstill, filters, promptly get honeysuckle flower liquid for treating comedo.This medicinal liquid cure rate height, and have no side effect.
Description
The present invention relates to a kind of Chinese medicinal liquid, particularly a kind of be main component with the Flos Lonicerae, cure mainly the dermopathic Chinese medicinal liquid of acne.
Acne claim acne again, it is one of common skin disease, treatment medically at present is often for oral administration or with preparation externals such as retinoid, antibiotics, benzoyl peroxide, sulfur lotions with vitamins, estrogen class, retinoid, endocrine preparation, antibiotics and zinc preparation, but effect is not good enough.Especially some Western medicine is because of there being side reaction safety inadequately.So up to the present also there is not a kind of specific drug that cures mainly acne.Continue to use traditional decoction oral or washout for the acne traditional Chinese medical science is many based on differential diagnosis of diseases determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs and differential diagnosis of diseases compound treatment, its prescription also varies with each individual, and does not form fixed dosage form, use extremely inconvenience, and effect is also not ideal.
The purpose of this invention is to provide a kind of good effect, safe in utilization easy be key component with the Flos Lonicerae, cure mainly the honeysuckle flower liquid for treating comedo of acne.
Scheme is to realize unhitching the object of the invention certainly: the honeysuckle flower liquid for treating comedo that is provided mainly is that the extracting solution by following material combines: 20～30 parts of Flos Loniceraes, 2.5～7.5 parts of Fructus Gardeniaes, 3.75～6.25 parts of Herba Taraxacis, each 2～3 parts of Cortex Dictamni, Fructus Cnidii, Herba Lycopi, the Radix Angelicae Dahuricae, Herba Asari, Semen Benincasae, Rhizoma Atractylodis and Rhizoma Cimicifugaes.
The inventor thinks from the angle of Chinese medicine: the cause of disease of acne mainly is that it is damp and hot to have the intestines and stomach concurrently based on wind and heat in the lung meridian, and the blood clots absorbing stagnates.Propose: the treatment to acne should be based on heat-clearing and toxic substances removing, dispelling wind and ventilating the lung, assistant with dampness, invigorate blood circulation, dispelling wind for relieving itching.Honeysuckle flower liquid for treating comedo provided by the present invention preparation with regard to being based on this theory.Flos Lonicerae wherein (also the someone is referred to as Flos Lonicerae) has heat-clearing and toxic substances removing, wind-heat dissipating effect for the monarch drug in the Chinese materia medica; Fructus Gardeniae, Herba Taraxaci are ministerial drug, and auxiliary Flos Lonicerae is to strengthen its heat-clearing toxin-expelling functions; Cortex Dictamni, Fructus Cnidii heat clearing and damp drying, Herba Asari, Radix Angelicae Dahuricae a surname lung meridian ailment said due to cold or exposure of loosing, Semen Benincasae, Rhizoma Atractylodis are drying damp and strengthening spleen, the pain that disappears of reducing phlegm, more than seven flavors be adjuvant drug altogether; Rhizoma Cimicifugae is a messenger drug, focuses on that to draw all medicines up, reaches in sick institute.
In above-mentioned ministerial drug, can also increase 2.5～7.5 parts of Herba Senecionis Scandentiss, 3.75～6.25 parts of Flos Chrysanthemi Indicis with heat-clearing and toxic substances removing, purging fire and cooling blood effect.In above-mentioned adjuvant drug, can also increase by 2～3 parts of Herba Menthaes, so that further heighten the effect of a treatment.
The best proportioning of above-mentioned each component is: 24～27 parts of Flos Loniceraes, 3～5 parts of Fructus Gardeniaes, 4～6 parts of Herba Taraxacis, 4～6 parts of Herba Senecionis Scandentiss, 4～5 parts of Flos Chrysanthemi Indicis, each 2～3 parts of Cortex Dictamni, Fructus Cnidii, Herba Lycopi, the Radix Angelicae Dahuricae, Herba Asari, Herba Menthae, Semen Benincasae, Rhizoma Atractylodis and Rhizoma Cimicifugaes.
Example 1
Take by weighing 26 parts of Flos Loniceraes; 4 parts of Fructus Gardeniaes cut sheet, drying; 5 parts of Herba Senecionis Scandentiss, cutting, drying; 4 parts of Flos Chrysanthemi Indicis; 2.5 parts of Cortex Dictamni, cut sheet, drying; 2.5 parts of Fructus Cnidiis; 2.5 parts of Herba Lycopi run through, cutting, drying; 2.5 parts of the Radixs Angelicae Dahuricae run through, cut sheet, drying; 2.5 parts of Herba Asaris, shower water moistens slightly, cutting is dried in the shade; 2.5 parts of Herba Menthaes, shower water moistens slightly, also cold drying in time of cutting; 2.5 parts of Semen Benincasaes pulverize; 2.5 parts of Rhizoma Atractylodis run through, cut sheet, drying; 2.5 parts of Rhizoma Cimicifugaes slightly steep, run through, cut sheet, drying.More than every part be 1 kilogram weight.
Above-mentioned each thing is mixed the back add 2 times of water gagings immersions 2 hours, carry out vapor distillation again, get distillate, then distillate is carried out the redistillation second time, in the end add 0.5% sodium benzoate antiseptic in the distillate of gained, leave standstill, filter, resulting colourless liquid is honeysuckle flower liquid for treating comedo.
It is the volatilizable character of extracting as much as possible in above-mentioned each thing that this product adopts the purpose of distil process, carry out single flash usually and get final product, but twice distillation can make product quality more stable.
Example 2
Take by weighing 20 parts of Flos Loniceraes, 7.5 parts of Fructus Gardeniaes, 4 parts of Herba Taraxacis, 3 parts of Herba Senecionis Scandentiss, each 2 parts of Cortex Dictamni, Fructus Cnidii, Herba Lycopi, the Radix Angelicae Dahuricae, Herba Asari, Semen Benincasae, Rhizoma Atractylodis and Rhizoma Cimicifugaes.Method for making is with example 1.
Example 3
Take by weighing 30 parts of Flos Loniceraes, 2.5 parts of Fructus Gardeniaes, 6.26 parts of Herba Taraxacis, 6 parts of Flos Chrysanthemi Indicis, each 3 parts of Cortex Dictamni, Fructus Cnidii, Herba Lycopi, the Radix Angelicae Dahuricae, Herba Asari, Herba Menthae, Semen Benincasae, Rhizoma Atractylodis and Rhizoma Cimicifugaes.Method for making is with example 1.
The usage of this product: behind the warm water cleaning affected part, with medicinal liquid partial smearing affected part, every day 3-5 time.Inactive cosmetics between the operating period, the greasy and pungent product of few edible oil.
The toxicological test of this product: all check by " specification requirement of new drug (Western medicine) toxicity ".
1, skin irritation test
Laboratory animal: rabbit.Method: local intact skin and damaged skin are smeared.
The result: the irritant reaction integration is zero, no local excitation reaction.
2, skin acute toxicity test
Laboratory animal: rabbit.Method: damaged skin is smeared with various dose.
Result: do not find the whole body poisoning symptom.
3, skin anaphylactic test
Laboratory animal: Cavia porcellus.
Result: do not find anaphylaxis.
4, acute toxicity test
Laboratory animal: white mice.Method: lumbar injection.
The result: minimum lethal dose is greater than 50g/kg, 6D
50Do not measure.
5, eye irritant test
Laboratory animal: rabbit.Method: in the eye conjunctival sac, inject this product.
The result: the average response value is zero, to the eye vacuum response.
The pharmacodynamics test of this product shows: this product can significantly suppress acute exudative inflammation and reduce capillary permeability; The paraplasm that androlin in the rat body is increased the sebaceous gland tissue morphology that causes has the obvious suppression effect, and can obviously reduce the quantity of sebaceous gland; The intravital serum Testosterone of rat level there is not obvious influence.
The clinical trial of this product:
Observe patient's totally 300 examples, all based on the out-patient.Be divided into treatment group and matched group, the treatment group is used this product, and matched group uses 10% sulfur lotion.
It is as shown in the table in two groups general curative effect contrast:
| Total routine number | Recovery from illness | Produce effects | Effectively | Invalid | Effectively total | |
| The treatment group | 240 | 88 (33.6) | 87 (36.3) | 47 (19.6) | 18 (7.5) | 222 (92.5) |
| Matched group | 60 | 9 (15) | 17 (28.3) | 14 (23.3) | 20 (33.3) | 40 (66.7) |
Numeral in the table bracket is a percent.
In above-mentioned clinical trial, be that the total effective rate of wind and heat in the lung meridian (totally 155 examples) is 94.8% to traditional Chinese medical science typing, be that the total effective rate of papular type (totally 203 examples) is 97.5% to the doctor trained in Western medicine typing.
From as can be seen above: the total effective rate of this product is 92.5%, and the recovery from illness obvious effective rate is 72.9%, all is significantly higher than sulfur lotion commonly used at present, and does not have tangible untoward reaction.
This product is a colourless liquid, and topical application does not have greasy feeling, and good absorbing is not stayed any vestige, and safe in utilization easy, and particularly for patient and the course of disease short patient of great majority for papular type, the onset of this product is rapid, better efficacy.
Claims (4)
1, a kind of honeysuckle flower liquid for treating comedo, it is characterized in that main extracting solution by following material combines: 20～30 parts of Flos Loniceraes, 2.5～7.5 parts of Fructus Gardeniaes, 3.75～6.25 parts of Herba Taraxacis, each 2～3 parts of Cortex Dictamni, Fructus Cnidii, Herba Lycopi, the Radix Angelicae Dahuricae, Herba Asari, Semen Benincasae, Rhizoma Atractylodis and Rhizoma Cimicifugaes.
2, honeysuckle flower liquid for treating comedo as claimed in claim 1 is characterized in that also being added with 2.5～7.5 parts of Herba Senecionis Scandentiss, 3.75～6.25 parts of Flos Chrysanthemi Indicis.
3, honeysuckle flower liquid for treating comedo as claimed in claim 2 is characterized in that also being added with 2～3 parts of Herba Menthaes.
4, honeysuckle flower liquid for treating comedo as claimed in claim 3 is characterized in that 24～27 parts of Flos Loniceraes, 3～5.5 parts of Fructus Gardeniaes, 4～6 parts of Herba Taraxacis, 4～6 parts of Herba Senecionis Scandentiss, 4～5 parts of Flos Chrysanthemi Indicis, each 2～3 parts of Cortex Dictamni, Fructus Cnidii, Herba Lycopi, the Radix Angelicae Dahuricae, Herba Asari, Herba Menthae, Semen Benincasae, Rhizoma Atractylodis and Rhizoma Cimicifugaes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 93107488 CN1085789A (en) | 1993-07-01 | 1993-07-01 | Honeysuckle flower liquid for treating comedo |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 93107488 CN1085789A (en) | 1993-07-01 | 1993-07-01 | Honeysuckle flower liquid for treating comedo |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1085789A true CN1085789A (en) | 1994-04-27 |
Family
ID=4986710
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 93107488 Pending CN1085789A (en) | 1993-07-01 | 1993-07-01 | Honeysuckle flower liquid for treating comedo |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1085789A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100360168C (en) * | 2005-12-14 | 2008-01-09 | 贾孝荣 | Chinese medicine composition for diminishing speckle and pox |
| CN102357157A (en) * | 2011-11-14 | 2012-02-22 | 纪承寅 | Traditional Chinese medicine composition for treating skin acne with mite infection |
| CN102771607A (en) * | 2012-08-16 | 2012-11-14 | 张士舜 | Herbal tea capable of eliminating excess fire and preparation method of herbal tea |
-
1993
- 1993-07-01 CN CN 93107488 patent/CN1085789A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100360168C (en) * | 2005-12-14 | 2008-01-09 | 贾孝荣 | Chinese medicine composition for diminishing speckle and pox |
| CN102357157A (en) * | 2011-11-14 | 2012-02-22 | 纪承寅 | Traditional Chinese medicine composition for treating skin acne with mite infection |
| CN102771607A (en) * | 2012-08-16 | 2012-11-14 | 张士舜 | Herbal tea capable of eliminating excess fire and preparation method of herbal tea |
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| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |