CN1055226C - Medicine for curing trichomadesis and its preparation method - Google Patents
Medicine for curing trichomadesis and its preparation method Download PDFInfo
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- CN1055226C CN1055226C CN96105615A CN96105615A CN1055226C CN 1055226 C CN1055226 C CN 1055226C CN 96105615 A CN96105615 A CN 96105615A CN 96105615 A CN96105615 A CN 96105615A CN 1055226 C CN1055226 C CN 1055226C
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Abstract
The present invention discloses a novel medicine for treating alopecia disease, which takes raw fleece-flower roots, chuanxiong rhizomes, notopterygium roots, gastrodia tubers, prepared rhizomes of rehmannia, mulberry fruits, Chinese angelica, fructus psoraleae, fried date kenels, cacumen biotae, radix et rhizoma rhei, ash barks, black sesame and honey as the raw material. The raw material is prepared with a proportion according to the different characteristics of each traditional Chinese medicine. The present invention is made by the respective treatment of drying, boiling, sterilization, etc. The present invention has a simple formulation and a simple preparation method. The total effective rate is more than 95% for alopecia areata, complete baldness, alopecia universalis and alopecia seborrheica. The present invention also has significant therapeutic effect on refractory alopecia.
Description
The present invention relates to a kind of medicine for the treatment of alopecia, is the Chinese patent medicine of preparation of raw material with the Chinese herbal medicine specifically, the invention still further relates to the preparation method of this medicine.
Alopecia is commonly encountered diseases, the frequently-occurring disease of department of dermatologry, its type has alopecia areata, alopecia totalis, alopecia universalis and seborrheic alopecia (comprising moist and the dryness seborrheic alopecia), pathogenic factor is not clear fully as yet at present, it is generally acknowledged relevant with factors such as heredity, endocrine disturbance, psychic trauma, neural malnutrition, trace element deficiency, immunologic dysfunction, infection, drug allergy.Due to illness because of not bright, so still do not have specific drugs in the treatment.According to epizootic disease investigation, its morbidity has the gesture that increases in recent years, how to treat and prevents primary disease to become the new problem of medical circle.
Though many medicinal applications are arranged in clinical both at home and abroad at present, run into following point:
Though 1, vitamins and cystine are taken for a long time and had no side effect, curative effect is very little.
Though 2, the traditional Chinese medical science has means such as percussopunctator, acupuncture, massage, bring certain misery to the patient, and curative effect is very little, the patient also should not accept mostly.
3, Chinese patent medicine for oral administration such as Alopecia Pill, the YANGXUE SHENGFA JIAONANG equal course of treatment of length, big, the weak curative effect of dose bring financial burden to the patient.
4, outer liniment can only take stopgap measures, and can not effect a permanent cure, and does not reach therapeutic purposes, though there have 101 HAIR REGENERATING MEDICINE to be applied to recently to be clinical, so cost an arm and a leg, and curative effect still unsatisfactory (, can not effect a permanent cure) because of also taking stopgap measures, very anaphylaxis appears in the person.
The object of the present invention is to provide a kind of alopecia therapeutic agent that has enhancing human body immunity, trace element supplement, endocrine regulation, trophic nerve, catharsis and toxin expelling, improves the effect of blood circulation of skin.
Another object of the present invention provides the preparation method of alopecia therapeutic agent.
Solution of the present invention is based on motherland's medical science to pathogenetic understanding of alopecia and Therapeutic Principle, with reference to modern pharmacological research, from motherland's medical treasure-house, filter out enriching yin and nourishing kidney, nourishing blood to expel wind, the natural edible-plant of the purging FU-organs of invigorating blood circulation, the body resistance strengthening and constitution consolidating, by the theory of Chinese medical science prescription, make the effect of its performance hair-growing and hair care.
Medicine of the present invention is made (consumption is a weight portion) by following component:
10～30 parts of 10～38 portions of Rhizoma Et Radix Notopterygiis of 10～40 parts of Rhizoma Chuanxiongs of Radix Polygoni Multiflori
10～30 parts of 10～40 parts of Fructus Mori of 10～35 parts of Radix Rehmanniaes Preparata of Rhizoma Gastrodiae
10～26 parts of 10～30 parts of Semen Ziziphi Spinosae (parched)s of 10～38 parts of Fructus Psoraleaes of Radix Angelicae Sinensis
5～25 parts of 5～20 parts of Cortex Fraxinis of 10～25 parts of Radix Et Rhizoma Rhei of Cacumen Platycladi
110～550 parts of 10～40 parts of Mel of Semen Sesami Nigrum
The formula optimization weight proportion scope of preparation medicine of the present invention is:
10～28 parts of 10～35 portions of Rhizoma Et Radix Notopterygiis of 10～35 parts of Rhizoma Chuanxiongs of Radix Polygoni Multiflori
10～26 parts of 10～37 parts of Fructus Mori of 10～25 parts of Radix Rehmanniaes Preparata of Rhizoma Gastrodiae
10～25 parts of 10～29 parts of Semen Ziziphi Spinosae (parched)s of 10～35 parts of Fructus Psoraleaes of Radix Angelicae Sinensis
5～15 parts of 5～12 parts of Cortex Fraxinis of 10～20 parts of Radix Et Rhizoma Rhei of Cacumen Platycladi
115～420 parts of 10～35 parts of Mel of Semen Sesami Nigrum
The optimum weight proportioning of medicine of the present invention is:
15 parts in 15 parts of Rhizoma Gastrodiaes of 18 portions of Rhizoma Et Radix Notopterygiis of 20 parts of Rhizoma Chuanxiongs of Radix Polygoni Multiflori
21 parts of 24 parts of Fructus Psoraleaes of 25 parts of Radix Angelicae Sinensis of 25 parts of Fructus Mori of Radix Rehmanniae Preparata
10 parts of 6 parts of Cortex Fraxinis of 10 parts of Radix Et Rhizoma Rhei of 15 portions of Cacumen Platycladis of Semen Ziziphi Spinosae (parched)
415 parts of 30 parts of Mel of Semen Sesami Nigrum
Above-mentioned each component is made medicine production method of the present invention is:
Get Radix Polygoni Multiflori, Rhizoma Chuanxiong, Rhizoma Et Radix Notopterygii, Rhizoma Gastrodiae, Fructus Mori, Radix Angelicae Sinensis, Fructus Psoraleae, Semen Ziziphi Spinosae (parched), Cacumen Platycladi, Radix Et Rhizoma Rhei, Cortex Fraxini, Semen Sesami Nigrum, oven dry and be crushed to 120 order fine powders, get Radix Rehmanniae Preparata and add 800～1000 milliliters in water, take 300 milliliters in juice for a long time, get Mel and put in the pot slow fire and decoct and be golden yellow.Medicated powder, Radix Rehmanniae Preparata water, Mel are stirred, make honeyed pill, sterilization treatment 30 minutes.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, to select natural plant for use be raw material in the present invention, and each component meets the pharmaceutical control law regulation, utilizes the comprehensive function treatment alopecia of the medicine of respectively distinguishing the flavor of, and no chemicals is nontoxic to human body, safe and reliable.
2, the present invention need not decoct, and the curative effect height is cheap, taking convenience, and dose is few, does not have any misery.
3, medicine of the present invention all can use separately alopecia areata, alopecia totalis, alopecia universalis or seborrheic alopecia, all can receive the effect of small wooden raft drum.Can unite use with outer liniment and outer lotion to part intractable seborrheic alopecia, can obviously increase curative effect.
4, medicine of the present invention can replace the medicine of other treatment alopecia fully according to clinical observation on the therapeutic effect.
5, medicine of the present invention has enhancing human body immunity, disappear fat and improve the effect of cutaneous circulation of trace element supplement, endocrine regulation, antibiotic, antiallergic, trophic nerve, catharsis and toxin expelling, dandruff removing.
6, medicine of the present invention has the effect of the body resistance strengthening and constitution consolidating, observes from a large amount of clinical trials, is not only a kind of novel alopeciaing therapeutic agent, also has the effect of treatment poliosis and hair care.
For showing the therapeutic effect of medicine of the present invention to alopecia, the present invention is through 750 examples (wherein alopecia areata 400 examples, seborrheic alopecia 350 examples) system's clinical observation, and selection medical history, the suitable alopecia areata patient of the state of an illness, age, sex and former Therapeutic Method 380 examples and use seborrheic alopecia patient 340 examples of outer liniment to be matched group, wherein male 394 examples, woman's 356 examples, 2～58 years old age, course of disease February～18 year.Test group: on former treatment basis, stop using for oral administration and apply medicinal lotion or ointment outward, take medicine of the present invention (former title Bollinger body hair-growth ballet, the clinical title hair speed in back is given birth to ball).Matched group: take YANGXUE SHENGFA JIAONANG routinely and use 101 HAIR REGENERATING MEDICINE to wipe treatment outward merely.3 months observation periods, 1 month is a course of treatment, totally 3 courses of treatment.
Instructions of taking: 1 ball/time, day clothes 3 times, ante cibum, clothes are taken or chewed to boiled water.Clinical test results is as table (1,2,3,4).
Table 1: take medicine of the present invention (hair speed is given birth to ball) and take the observation of curative effect of YANGXUE SHENGFA JIAONANG.
| Alopecia areata | Group | Case load | Cure | Take a turn for the better | Do not heal | Total effective rate (%) |
| Test group | 400 | 312 | 79 | 9 | 97.75 | |
| Matched group | 380 | 75 | 21 | 284 | 25.26 | |
| u | 20.08＞2.58 | |||||
| p | ＜0.01 | |||||
Table 2: take medicine of the present invention and observe with the hair growth of taking YANGXUE SHENGFA JIAONANG.
| Alopecia areata | The course of treatment | Experimental group | Matched group | Add up to |
| One course of treatment | 203 | 78 | 281 | |
| Two courses of treatment | 115 | 13 | 128 | |
| Three courses of treatment | 73 | 5 | 78 | |
| Add up to | 391 | 96 | 487 | |
| x 2 | 27.57＞0.001(2)13.816 p ＜0.001 | |||
Table 3: take medicine of the present invention and the outer observation of curative effect of wiping 101 HAIR REGENERATING MEDICINE.
| Seborrheic alopecia | Group | Case load | Cure | Take a turn for the better | Do not heal | Total effective rate (%) |
| Test group | 350 | 216 | 119 | 15 | 95.71 | |
| Matched group | 340 | 15 | 43 | 282 | 17.06 | |
| u | 20.81＞2.58 | |||||
| p | ＜0.01 | |||||
Table 4: the hair growth after taking medicine of the present invention and wiping 101 HAIR REGENERATING MEDICINE is outward observed.
Test statistics shows: with medicine of the present invention 400 routine alopecia areata patients are done therapeutic test, that obtains significant curative effect accounts for 78%, improvement account for 19.75%, invalid accounts for 2.25%, total effective rate reaches 97.75%.350 routine seborrheic alopecia patients are done therapeutic test, and that obtains significant curative effect accounts for 61.71%, improvement account for 34%, invalid accounts for 4.29%, total effective rate reaches 95.71%.Illustrate that curative effect of medication of the present invention is conclusive, clinical expansion use value is arranged.
| Seborrheic alopecia | The course of treatment | Experimental group | Matched group | Add up to |
| One course of treatment | 189 | 31 | 220 | |
| Two courses of treatment | 118 | 25 | 143 | |
| Three courses of treatment | 38 | 2 | 40 | |
| Add up to | 345 | 58 | 403 | |
| x 2 | 4.19＞0.20 (2)3.219 p＜0.20 | |||
Embodiment
Take by weighing raw material by following proportioning:
29 kilograms in 25 kilograms of Rhizoma Gastrodiaes of 28 kilograms of Rhizoma Et Radix Notopterygiis of 30 kilograms of Rhizoma Chuanxiongs of Radix Polygoni Multiflori
20 kilograms of 26 kilograms of Fructus Psoraleaes of 22 kilograms of Radix Angelicae Sinensis of 23 kilograms of Fructus Mori of Radix Rehmanniae Preparata
10 kilograms of 6 kilograms of Cortex Fraxinis of 15 kilograms of Cacumen Platycladis of Semen Ziziphi Spinosae (parched), 10 kilogram of raw Radix Et Rhizoma Rhei
315 kilograms of 30 kilograms of Mel of Semen Sesami Nigrum
Production method is as follows:
Get Radix Polygoni Multiflori, Rhizoma Chuanxiong, Rhizoma Et Radix Notopterygii, Rhizoma Gastrodiae, Radix Rehmanniae Preparata, Fructus Mori, Radix Angelicae Sinensis, Fructus Psoraleae, Semen Ziziphi Spinosae (parched), Cacumen Platycladi, Radix Et Rhizoma Rhei, Cortex Fraxini, the Semen Sesami Nigrum oven dry is crushed to 120 order fine powders, get Radix Rehmanniae Preparata and add 800～1000 milliliters in water, take 300 milliliters in juice for a long time, get Mel and put in the pot slow fire and decoct and be golden yellow.Medicated powder, Radix Rehmanniae Preparata water, Mel are stirred, make honeyed pill, every ball size is 9 grams, sterilization treatment 30 minutes.
Claims (6)
1, a kind of medicine for the treatment of alopecia is characterized in that it is the medicament of making by with following materials of weight proportions
10～30 parts of 10～38 portions of Rhizoma Et Radix Notopterygiis of 10～40 parts of Rhizoma Chuanxiongs of Radix Polygoni Multiflori
10～30 parts of 10～40 parts of Fructus Mori of 10～35 parts of Radix Rehmanniaes Preparata of Rhizoma Gastrodiae
10～26 parts of 10～30 parts of Semen Ziziphi Spinosae (parched)s of 10～38 parts of Fructus Psoraleaes of Radix Angelicae Sinensis
5～25 parts of 5～20 parts of Cortex Fraxinis of 10～25 parts of Radix Et Rhizoma Rhei of Cacumen Platycladi
110～550 parts of 10～40 parts of Mel of Semen Sesami Nigrum.
2, the medicine of treatment alopecia according to claim 1, wherein the weight proportion of each raw material is
10～28 parts of 10～35 portions of Rhizoma Et Radix Notopterygiis of 10～35 parts of Rhizoma Chuanxiongs of Radix Polygoni Multiflori
10～26 parts of 10～37 parts of Fructus Mori of 10～25 parts of Radix Rehmanniaes Preparata of Rhizoma Gastrodiae
10～25 parts of 10～29 parts of Semen Ziziphi Spinosae (parched)s of 10～35 parts of Fructus Psoraleaes of Radix Angelicae Sinensis
5～15 parts of 5～12 parts of Cortex Fraxinis of 10～20 parts of Radix Et Rhizoma Rhei of Cacumen Platycladi
115～420 parts of 10～35 parts of Mel of Semen Sesami Nigrum.
3, the medicine of treatment alopecia according to claim 1, wherein the weight proportion of each raw material is
15 parts in 15 parts of Rhizoma Gastrodiaes of 18 portions of Rhizoma Et Radix Notopterygiis of 20 parts of Rhizoma Chuanxiongs of Radix Polygoni Multiflori
21 parts of 24 parts of Fructus Psoraleaes of 25 parts of Radix Angelicae Sinensis of 25 parts of Fructus Mori of Radix Rehmanniae Preparata
10 parts of 6 parts of Cortex Fraxinis of 10 parts of Radix Et Rhizoma Rhei of 15 portions of Cacumen Platycladis of Semen Ziziphi Spinosae (parched)
415 parts of 30 parts of Mel of Semen Sesami Nigrum.
4,, it is characterized in that said medicament is a said dosage form on any pharmaceutics according to the medicine of claim 1,2 or 3 described treatment alopecias.
5, the medicine of treatment alopecia according to claim 4 is characterized in that said medicament is a pill.
6, according to the compound method of the medicine of the described treatment alopecia of claim 5, it is characterized in that getting Radix Polygoni Multiflori, Rhizoma Chuanxiong, Rhizoma Et Radix Notopterygii, Rhizoma Gastrodiae, Fructus Mori, Radix Angelicae Sinensis, Fructus Psoraleae, Semen Ziziphi Spinosae (parched), Cacumen Platycladi, Radix Et Rhizoma Rhei, Cortex Fraxini, the Semen Sesami Nigrum oven dry is crushed to 120 order fine powders, get Radix Rehmanniae Preparata and add water 800-1000 milliliter, take 300 milliliters in juice for a long time, getting Mel puts in the pot slow fire and decocts and be golden yellow, medicated powder, Radix Rehmanniae Preparata water, Mel are stirred, make pill, sterilization treatment 30 minutes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN96105615A CN1055226C (en) | 1996-04-27 | 1996-04-27 | Medicine for curing trichomadesis and its preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN96105615A CN1055226C (en) | 1996-04-27 | 1996-04-27 | Medicine for curing trichomadesis and its preparation method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1137919A CN1137919A (en) | 1996-12-18 |
| CN1055226C true CN1055226C (en) | 2000-08-09 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN96105615A Expired - Fee Related CN1055226C (en) | 1996-04-27 | 1996-04-27 | Medicine for curing trichomadesis and its preparation method |
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| Country | Link |
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| CN (1) | CN1055226C (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1094368C (en) * | 1999-10-15 | 2002-11-20 | 程丁厚 | Chinese medicine for treating alopecia |
| CN100387288C (en) * | 2006-08-28 | 2008-05-14 | 余婧 | Medicated wine for treating poliosis and alopecia |
| CN103083555B (en) * | 2011-11-01 | 2015-03-18 | 邓永峰 | Pharmaceutical composition capable of growing and blackening hair and preparation method thereof |
| CN102688395B (en) * | 2012-05-08 | 2015-03-25 | 安徽智远生物科技有限公司 | Traditional Chinese medicine for treating alopecia areata and method for preparing same |
| CN102895532B (en) * | 2012-09-29 | 2014-05-14 | 蒋金洲 | Traditional Chinese medicine composition for treating alopecia areata |
| CN108066727A (en) * | 2017-04-20 | 2018-05-25 | 刘建华 | A kind of Chinese medicine alopecia formula and preparation method |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1035436A (en) * | 1988-12-28 | 1989-09-13 | 王玉花 | A kind of manufacture method of hair growth promoter |
| CN1081612A (en) * | 1992-07-28 | 1994-02-09 | 潘晓笛 | The Recipe of ginseng hair-blackening cream |
-
1996
- 1996-04-27 CN CN96105615A patent/CN1055226C/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1035436A (en) * | 1988-12-28 | 1989-09-13 | 王玉花 | A kind of manufacture method of hair growth promoter |
| CN1081612A (en) * | 1992-07-28 | 1994-02-09 | 潘晓笛 | The Recipe of ginseng hair-blackening cream |
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| Publication number | Publication date |
|---|---|
| CN1137919A (en) | 1996-12-18 |
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