CN108578460A - A kind of processing method of Herba Epimedii medicine materical crude slice - Google Patents

A kind of processing method of Herba Epimedii medicine materical crude slice Download PDF

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Publication number
CN108578460A
CN108578460A CN201810409730.5A CN201810409730A CN108578460A CN 108578460 A CN108578460 A CN 108578460A CN 201810409730 A CN201810409730 A CN 201810409730A CN 108578460 A CN108578460 A CN 108578460A
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Prior art keywords
herba epimedii
crude slice
materical crude
medicine materical
raw material
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CN201810409730.5A
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Chinese (zh)
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张宗强
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Sichuan Yudingtang Chinese Herbal Pieces Co Ltd
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Sichuan Yudingtang Chinese Herbal Pieces Co Ltd
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Priority to CN201810409730.5A priority Critical patent/CN108578460A/en
Publication of CN108578460A publication Critical patent/CN108578460A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296Epimedium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/13Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/15Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/17Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention relates to a kind of processing methods of Herba Epimedii medicine materical crude slice, include the following steps successively:Sorting, rinsing, demulcen, chopping piece, drying, airing and selection by winnowing.The processing method of the present invention, it is simple for process, it is easy to operate, fast and effeciently the medicinal part of Herba Epimedii can be detached with dis-medicinal part, the production efficiency of Herba Epimedii medicine materical crude slice is substantially increased, and has saved a large amount of labour and cost of labor, and the excessive sheep medicine materical crude slice quality processed is high.

Description

A kind of processing method of Herba Epimedii medicine materical crude slice
Technical field
The present invention relates to field of medicinal materials processing, specifically a kind of processing method of Herba Epimedii medicine materical crude slice.
Background technology
Currently, the processing method for being directed to Herba Epimedii in the market is all the traditional diamond-making technique used based on artificial:Sort- Profit-cutting-drying-packaging is washed, since medicinal herb grower is in the gatherer process of Herba Epimedii, is all that Herba Epimedii is connected into root excavation, is sorting When mixed and disorderly root adulterate so that sorting process takes, takes a lot of work, and mixed and disorderly root is not readily separated, and leads to later stage process of manufacture It is very cumbersome.
For traditional processing method based on every 1000kg epimedium herbs, worker needs 15 working days that can just machine, Not only working, time-consuming, wastes a large amount of manpower and financial resources, but also manual operation makes quality be difficult to stablize so that enterprise The high labor cost that industry is put into Herba Epimedii process, to increase processing cost.
Invention content
In order to overcome the above-mentioned problems in the prior art, a kind of currently proposed processing method of Herba Epimedii medicine materical crude slice.This The processing method of invention, it is simple for process, it is easy to operate, it can be fast and effeciently by the medicinal part of Herba Epimedii and dis-medicinal part point From substantially increasing the production efficiency of Herba Epimedii medicine materical crude slice, and saved a large amount of labour and cost of labor, and process Excessive sheep medicine materical crude slice quality it is high.
To realize the above-mentioned technical purpose, technical solution of the present invention is as follows:
A kind of processing method of Herba Epimedii medicine materical crude slice, it is characterised in that include the following steps successively:
It sorts:Herba Epimedii raw material is taken, the impurity for sorting and removing in Herba Epimedii raw material is first passed through;
Rinsing:Herba Epimedii raw material after sorting is sent into medicine-washing machine, the soil on Herba Epimedii raw material surface is washed away;
Demulcen:Herba Epimedii raw material after rinsing is sent into medicine processing device, without the dry heart in profit to Herba Epimedii raw material;
Chopping piece:Herba Epimedii raw material after demulcen is sent into vertical cut formula medicine cutter, Herba Epimedii raw material is cut into excessive sheep The width of leaves of pulse plants silk piece, every section of Herba Epimedii silk piece is 5-10mm;
Drying:Herba Epimedii silk piece is deposited in by the thickness of 4-6cm in the drying tray of drying unit and is dried, after drying The Herba Epimedii silk piece that water content is 8-10% is obtained, the temperature of drying is 75-80 DEG C, and the time of drying is 2-4 hours;
Airing;Herba Epimedii silk piece after drying is deposited in by the thickness of 8-10cm on tedding table, airing to room temperature;
Selection by winnowing:Herba Epimedii silk tablet raw material after airing is sent into winnowing machine and carries out selection by winnowing, obtains Herba Epimedii medicine materical crude slice.
In the baking step, drying unit is drying room or dryer.
In the winnowing step, the rotating speed of winnowing machine is 1400-1600 revs/min.
In the airing step, natural wind 1- is blowed toward the Herba Epimedii silk piece surface being deposited on tedding table using air-cooler 2 hours.
Further include determination of extractives step, the determination of extractives step refers to that Herba Epimedii medicine materical crude slice is taken to be leached according to alcohol-soluble The cold-maceration of object measuring method (general rule 2201) carries out extract content measurement, and Diluted Alcohol, which is added, in continuous mode makees solvent, excessive sheep Extract >=15.0% in leaves of pulse plants medicine materical crude slice.
Further include epimedin C assay step, the epimedin C assay step refer to take Herba Epimedii medicine materical crude slice according to High performance liquid chromatography (general rule 0512) carries out epimedin C assay, content >=1.0% of epimedin C in Herba Epimedii medicine materical crude slice.
Compared with prior art, the present invention the advantage is that:
1, processing method of the invention, it is simple for process, it is easy to operate, can fast and effeciently by the medicinal part of Herba Epimedii with Dis-medicinal part detach, substantially increase the production efficiency of Herba Epimedii medicine materical crude slice, and saved a large amount of labour and manually at This, and the excessive sheep medicine materical crude slice quality processed is high.
2, processing method of the invention is compared with traditional processing method:
The processing method of the present invention is based on every 1000kg epimedium herbs, it is only necessary to and 6 working days can machine, from Traditional processing needs be condensed to for 15 days 6 days, and it is short that mechanized operation makes work take, and processing efficiency integrally improves 60%, also effective It avoids manual operation that quality is made to be difficult to stable situation and occur, substantially increases the production efficiency of Herba Epimedii medicine materical crude slice, and And a large amount of cost of labor is saved.
3, the present invention uses winnowing step, and Herba Epimedii silk tablet raw material after airing is sent into winnowing machine and carries out selection by winnowing, is obtained Herba Epimedii medicine materical crude slice.The purpose of selection by winnowing is to detach mixed shorthorned epimedium root in Herba Epimedii silk piece with Herba Epimedii silk piece, and removing is mixed into Shorthorned epimedium root, improve Herba Epimedii medicine materical crude slice quality and quality.
4, the present invention is using in the airing step, using air-cooler toward the Herba Epimedii silk piece surface being deposited on tedding table Blow natural wind 1-2 hours.The cooling time of Herba Epimedii silk piece has been saved in the cooling that can accelerate Herba Epimedii silk piece, to carry The high production efficiency of Herba Epimedii medicine materical crude slice.
5, the present invention is using further including determination of extractives step, the determination of extractives step refer to take Herba Epimedii medicine materical crude slice by According to the cold-maceration progress determination of extractives of ethanol soluble extractives measuring method (general rule 2201), addition Diluted Alcohol is made molten in continuous mode Agent, extract >=15.0% in Herba Epimedii medicine materical crude slice.According to《Pharmacopeia》2015 editions requirements are to the extract in Herba Epimedii medicine materical crude slice It is measured, ensures that the extract in the Herba Epimedii medicine materical crude slice that my company processes meets《Pharmacopeia》2015 editions requirements.
6, further include epimedin C assay step, the epimedin C assay step refer to take Herba Epimedii medicine materical crude slice by Epimedin C assay is carried out according to high performance liquid chromatography (general rule 0512), the content of epimedin C in Herba Epimedii medicine materical crude slice >= 1.0%.According to《Pharmacopeia》2015 editions requirements are measured the content of epimedin C in Herba Epimedii medicine materical crude slice, ensure that my company adds The content of epimedin C meets in the Herba Epimedii medicine materical crude slice that work goes out《Pharmacopeia》2015 editions requirements.
Specific implementation mode
The present invention is further detailed below:
Embodiment 1:
A kind of processing method of Herba Epimedii medicine materical crude slice, includes the following steps successively:
It sorts:Herba Epimedii raw material is taken, the impurity for sorting and removing in Herba Epimedii raw material is first passed through;
Rinsing:Herba Epimedii raw material after sorting is sent into medicine-washing machine, the soil on Herba Epimedii raw material surface is washed away;
Demulcen:Herba Epimedii raw material after rinsing is sent into medicine processing device, without the dry heart in profit to Herba Epimedii raw material;
Chopping piece:Herba Epimedii raw material after demulcen is sent into vertical cut formula medicine cutter, Herba Epimedii raw material is cut into excessive sheep The width of leaves of pulse plants silk piece, every section of Herba Epimedii silk piece is 5mm;
Drying:Herba Epimedii silk piece is deposited in by the thickness of 4cm in the drying tray of drying unit and is dried, after drying The temperature of the Herba Epimedii silk piece for being 10% to water content, drying is 75 DEG C, and the time of drying is 2 hours;
Airing;Herba Epimedii silk piece after drying is deposited in by the thickness of 8cm on tedding table, airing to room temperature;
Selection by winnowing:Herba Epimedii silk tablet raw material after airing is sent into winnowing machine and carries out selection by winnowing, obtains Herba Epimedii medicine materical crude slice.
In baking step described in the present embodiment, the drying unit is drying room.
In winnowing step described in the present embodiment, the rotating speed of the winnowing machine is 1400 revs/min.
In the present embodiment, medicine-washing machine is XY900 type medicine-washing machines, and vertical cut formula medicine cutter is QYJ200 type vertical cut formula medicine cutters.
Embodiment 2:
A kind of processing method of Herba Epimedii medicine materical crude slice, includes the following steps successively:
It sorts:Herba Epimedii raw material is taken, the impurity for sorting and removing in Herba Epimedii raw material is first passed through;
Rinsing:Herba Epimedii raw material after sorting is sent into medicine-washing machine, the soil on Herba Epimedii raw material surface is washed away;
Demulcen:Herba Epimedii raw material after rinsing is sent into medicine processing device, without the dry heart in profit to Herba Epimedii raw material;
Chopping piece:Herba Epimedii raw material after demulcen is sent into vertical cut formula medicine cutter, Herba Epimedii raw material is cut into excessive sheep The width of leaves of pulse plants silk piece, every section of Herba Epimedii silk piece is 7mm;
Drying:Herba Epimedii silk piece is deposited in by the thickness of 4-5 in the drying tray of drying unit and is dried, after drying The temperature of the Herba Epimedii silk piece for being 9% to water content, drying is 77 DEG C, and the time of drying is 3 hours;
Airing;Herba Epimedii silk piece after drying is deposited in by the thickness of 9cm on tedding table, airing to room temperature;
Selection by winnowing:Herba Epimedii silk tablet raw material after airing is sent into winnowing machine and carries out selection by winnowing, obtains Herba Epimedii medicine materical crude slice.
In baking step described in the present embodiment, the drying unit is dryer.
In winnowing step described in the present embodiment, the rotating speed of the winnowing machine is 1500 revs/min.
It is excessive on tedding table toward being deposited in using air-cooler in the airing step in airing step described in the present embodiment Sheep leaves of pulse plants silk piece surface blows natural wind 1 hour.
In the present embodiment, medicine-washing machine is XY720 type medicine-washing machines, and vertical cut formula medicine cutter is QYJ200 type vertical cut formula medicine cutters.
Embodiment 3:
A kind of processing method of Herba Epimedii medicine materical crude slice, includes the following steps successively:
It sorts:Herba Epimedii raw material is taken, the impurity for sorting and removing in Herba Epimedii raw material is first passed through;
Rinsing:Herba Epimedii raw material after sorting is sent into medicine-washing machine, the soil on Herba Epimedii raw material surface is washed away;
Demulcen:Herba Epimedii raw material after rinsing is sent into medicine processing device, without the dry heart in profit to Herba Epimedii raw material;
Chopping piece:Herba Epimedii raw material after demulcen is sent into vertical cut formula medicine cutter, Herba Epimedii raw material is cut into excessive sheep The width of leaves of pulse plants silk piece, every section of Herba Epimedii silk piece is 10mm;
Drying:Herba Epimedii silk piece is deposited in by the thickness of 6cm in the drying tray of drying unit and is dried, after drying The temperature of the Herba Epimedii silk piece for being 8% to water content, drying is 80 DEG C, and the time of drying is 4 hours;
Airing;Herba Epimedii silk piece after drying is deposited in by the thickness of 10cm on tedding table, airing to room temperature;
Selection by winnowing:Herba Epimedii silk tablet raw material after airing is sent into winnowing machine and carries out selection by winnowing, obtains Herba Epimedii medicine materical crude slice.
In baking step described in the present embodiment, institute's drying unit is dryer.
In winnowing step described in the present embodiment, the rotating speed of the winnowing machine is 1600 revs/min.
In airing step described in the present embodiment, blowed toward the Herba Epimedii silk piece surface being deposited on tedding table using air-cooler Natural wind 2 hours.
In the present embodiment, medicine-washing machine is XY500 type medicine-washing machines, and vertical cut formula medicine cutter is QYJ200 type vertical cut formula medicine cutters.
Embodiment 4:
With embodiment 1,2 and 3 the difference is that:Further include determination of extractives step, the determination of extractives step Refer to that Herba Epimedii medicine materical crude slice is taken to carry out determination of extractives according to the cold-maceration of ethanol soluble extractives measuring method (general rule 2201), measured Diluted Alcohol is added in journey and makees solvent, extract >=15.0% in Herba Epimedii medicine materical crude slice.
Embodiment 5:
With embodiment 4 the difference is that:Further include epimedin C assay step, the epimedin C assay Step refers to that Herba Epimedii medicine materical crude slice is taken to carry out epimedin C assay, Herba Epimedii drink according to high performance liquid chromatography (general rule 0512) Content >=1.0% of epimedin C in piece.
The present invention is not limited to the above embodiments, and the other embodiments obtained according to the technical solution that this is invented in fact should all be fallen into In protection scope of the present invention.

Claims (6)

1. a kind of processing method of Herba Epimedii medicine materical crude slice, it is characterised in that include the following steps successively:
It sorts:Herba Epimedii raw material is taken, the impurity for sorting and removing in Herba Epimedii raw material is first passed through;
Rinsing:Herba Epimedii raw material after sorting is sent into medicine-washing machine, the soil on Herba Epimedii raw material surface is washed away;
Demulcen:Herba Epimedii raw material after rinsing is sent into medicine processing device, without the dry heart in profit to Herba Epimedii raw material;
Chopping piece:Herba Epimedii raw material after demulcen is sent into vertical cut formula medicine cutter, Herba Epimedii raw material is cut into Herba Epimedii silk The width of piece, every section of Herba Epimedii silk piece is 5-10mm;
Drying:Herba Epimedii silk piece is deposited in by the thickness of 4-6cm in the drying tray of drying unit and is dried, is obtained after drying Water content is the Herba Epimedii silk piece of 8-10%, and the temperature of drying is 75-80 DEG C, and the time of drying is 2-4 hours;
Airing;Herba Epimedii silk piece after drying is deposited in by the thickness of 8-10cm on tedding table, airing to room temperature;
Selection by winnowing:Herba Epimedii silk tablet raw material after airing is sent into winnowing machine and carries out selection by winnowing, obtains Herba Epimedii medicine materical crude slice.
2. a kind of processing method of Herba Epimedii medicine materical crude slice according to claim 1, it is characterised in that:In the baking step, Drying unit is drying room or dryer.
3. a kind of processing method of Herba Epimedii medicine materical crude slice according to claim 1, it is characterised in that:In the winnowing step, The rotating speed of winnowing machine is 1400-1600 revs/min.
4. a kind of processing method of Herba Epimedii medicine materical crude slice according to claim 1, it is characterised in that:In the airing step, Natural wind is blowed 1-2 hours toward the Herba Epimedii silk piece surface being deposited on tedding table using air-cooler.
5. a kind of processing method of Herba Epimedii medicine materical crude slice according to claim 1, it is characterised in that:It further include determination of extractives Step, the determination of extractives step refer to taking Herba Epimedii medicine materical crude slice according to the cold soaking of ethanol soluble extractives measuring method (general rule 2201) Method carries out determination of extractives, and Diluted Alcohol, which is added, in continuous mode makees solvent, extract >=15.0% in Herba Epimedii medicine materical crude slice.
6. a kind of processing method of Herba Epimedii medicine materical crude slice according to claim 1, it is characterised in that:Further include that epimedin C contains Determination step is measured, the epimedin C assay step refers to taking Herba Epimedii medicine materical crude slice according to high performance liquid chromatography (general rule 0512) epimedin C assay is carried out, content >=1.0% of epimedin C in Herba Epimedii medicine materical crude slice.
CN201810409730.5A 2018-05-02 2018-05-02 A kind of processing method of Herba Epimedii medicine materical crude slice Pending CN108578460A (en)

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CN109793768A (en) * 2019-03-22 2019-05-24 辰风农业科技(北京)有限公司 A kind of processing of crude drugs processing method improving Icariin content
CN111686144A (en) * 2020-07-20 2020-09-22 兰州大学 Integrated preparation method for processing epimedium
CN115804800A (en) * 2022-12-21 2023-03-17 洛阳康鑫中药饮片有限公司 Epimedium production process

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Application publication date: 20180928