CN108572255B - 检测pd-l1+循环肿瘤细胞的试剂在筛选癌症风险个体以及在癌症患者预后中的应用 - Google Patents
检测pd-l1+循环肿瘤细胞的试剂在筛选癌症风险个体以及在癌症患者预后中的应用 Download PDFInfo
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- CN108572255B CN108572255B CN201810210273.7A CN201810210273A CN108572255B CN 108572255 B CN108572255 B CN 108572255B CN 201810210273 A CN201810210273 A CN 201810210273A CN 108572255 B CN108572255 B CN 108572255B
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- G01N33/575—
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- G01N33/57595—
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- G01N33/5753—
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/492—Determining multiple analytes
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
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- G01N33/57535—
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- G01N33/57557—
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- G01N33/5759—
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762471083P | 2017-03-14 | 2017-03-14 | |
| US62/471,083 | 2017-03-14 | ||
| US201762584634P | 2017-11-10 | 2017-11-10 | |
| US62/584,634 | 2017-11-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN108572255A CN108572255A (zh) | 2018-09-25 |
| CN108572255B true CN108572255B (zh) | 2023-05-16 |
Family
ID=61868129
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810210273.7A Active CN108572255B (zh) | 2017-03-14 | 2018-03-14 | 检测pd-l1+循环肿瘤细胞的试剂在筛选癌症风险个体以及在癌症患者预后中的应用 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20180267046A1 (enExample) |
| EP (1) | EP3376227B1 (enExample) |
| JP (1) | JP2018155752A (enExample) |
| KR (1) | KR20180105091A (enExample) |
| CN (1) | CN108572255B (enExample) |
| AU (1) | AU2018201819A1 (enExample) |
| CA (1) | CA2998065A1 (enExample) |
| TW (1) | TWI786095B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110142068B (zh) * | 2019-06-12 | 2024-02-02 | 杭州华得森生物技术有限公司 | 一种上皮间质混合型循环肿瘤细胞检测试剂盒及方法 |
| CN111551718A (zh) * | 2020-04-20 | 2020-08-18 | 山东第一医科大学(山东省医学科学院) | 一种检测前列腺癌患者外周血循环肿瘤细胞pd-l1表达的免疫荧光试剂盒及检测方法 |
| CN111562375B (zh) * | 2020-04-20 | 2022-05-06 | 山东第一医科大学(山东省医学科学院) | 一种检测胃癌患者外周血循环肿瘤细胞pd-l1表达的免疫荧光试剂盒及检测方法 |
| TWI874453B (zh) * | 2020-09-17 | 2025-03-01 | 日商細胞雲股份有限公司 | 使用末稍血循環腫瘤細胞之解析的癌症治療方法 |
| RU2738563C1 (ru) * | 2020-09-18 | 2020-12-14 | Ен Джун Чой | Способ прогноза малигнизации и ранней диагностики злокачественных опухолей |
| CN120559253A (zh) * | 2025-05-30 | 2025-08-29 | 中国医学科学院肿瘤医院 | Pd-l1阳性循环肿瘤细胞在肝癌免疫治疗中的应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010096734A2 (en) * | 2009-02-20 | 2010-08-26 | John Wayne Cancer Institute | B7-h3 antibody coupled bead assay for isolation and detection of circulating tumor cells in body fluids of melanoma and breast cancer patients |
| US20170242016A1 (en) * | 2014-10-15 | 2017-08-24 | Epic Sciences, Inc. | Circulating tumor cell diagnostics for therapy targeting pd-l1 |
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2018
- 2018-03-13 US US15/919,734 patent/US20180267046A1/en not_active Abandoned
- 2018-03-14 EP EP18161647.5A patent/EP3376227B1/en active Active
- 2018-03-14 JP JP2018046822A patent/JP2018155752A/ja active Pending
- 2018-03-14 CN CN201810210273.7A patent/CN108572255B/zh active Active
- 2018-03-14 AU AU2018201819A patent/AU2018201819A1/en not_active Abandoned
- 2018-03-14 CA CA2998065A patent/CA2998065A1/en active Pending
- 2018-03-14 TW TW107108604A patent/TWI786095B/zh active
- 2018-03-14 KR KR1020180029879A patent/KR20180105091A/ko not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JP2018155752A (ja) | 2018-10-04 |
| US20180267046A1 (en) | 2018-09-20 |
| TW201902534A (zh) | 2019-01-16 |
| EP3376227C0 (en) | 2024-02-21 |
| KR20180105091A (ko) | 2018-09-27 |
| EP3376227A1 (en) | 2018-09-19 |
| CN108572255A (zh) | 2018-09-25 |
| AU2018201819A1 (en) | 2018-10-04 |
| EP3376227B1 (en) | 2024-02-21 |
| CA2998065A1 (en) | 2018-09-14 |
| TWI786095B (zh) | 2022-12-11 |
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