CN108567673A - Stem of noble dendrobium freckle-removing mask and preparation method thereof - Google Patents

Stem of noble dendrobium freckle-removing mask and preparation method thereof Download PDF

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Publication number
CN108567673A
CN108567673A CN201810850799.1A CN201810850799A CN108567673A CN 108567673 A CN108567673 A CN 108567673A CN 201810850799 A CN201810850799 A CN 201810850799A CN 108567673 A CN108567673 A CN 108567673A
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stem
preparation
noble dendrobium
freckle
removing mask
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余芳
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/29Titanium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9706Algae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/981Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
    • A61K8/982Reproductive organs; Embryos, Eggs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/82Preparation or application process involves sonication or ultrasonication

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
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  • Birds (AREA)
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  • Mycology (AREA)
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  • Chemical & Material Sciences (AREA)
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  • Reproductive Health (AREA)
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  • Developmental Biology & Embryology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a kind of stem of noble dendrobium freckle-removing mask and preparation method thereof, which includes:1)Stem of noble dendrobium branch, tealeaves, seaweed, Jasmine, ginger and tulip are crushed, ultrasonic vibration and heating are then soaked in water and carry out, is then centrifuged for taking supernatant to obtain plant extracts;2)Polyethylene alcohol and water is mixed and heated for the first time, titanium dioxide, glycerine, vitamin E, allantoin, egg white, coconut juice and plant extracts is subsequently added into and carries out secondary mixing so that stem of noble dendrobium freckle-removing mask is made.The stem of noble dendrobium freckle-removing mask has excellent therapeutic effect for whelk, while the preparation method has the advantages that process is simple and raw material is easy to get.

Description

Stem of noble dendrobium freckle-removing mask and preparation method thereof
Technical field
The present invention relates to facial masks, and in particular, to a kind of stem of noble dendrobium freckle-removing mask and preparation method thereof.
Background technology
In different age levels, people are susceptible to different types of spot on the face.Common pigmented spots include:Too field Mole, freckle, sunburn, senile plaque etc..Pigmented spots are caused by a variety of factors:First, parents certain colors related with heredity Disposition skin disease entails the next generation;Second is that endocrine disorder causes pigmentation;Third, irregular living habit, for a long time Stress cause cutaneous pigmentation;Fourth, the scar that wound, acne etc. leave, can also leave pigmentation.
Currently, the method for nti-freckle includes drug therapy(Western medicine, Chinese medicine), physiotherapy(Such as red blue-light treatment), also have Beauty mask is treated;But the defect of existing facial mask treatment generally existing therapeutic effect difference.
Invention content
The object of the present invention is to provide a kind of stem of noble dendrobium freckle-removing masks and preparation method thereof, and the stem of noble dendrobium freckle-removing mask is for the youth Acne has excellent therapeutic effect, while the preparation method has the advantages that process is simple and raw material is easy to get.
To achieve the goals above, the present invention provides a kind of preparation methods of stem of noble dendrobium freckle-removing mask, including:
1)Stem of noble dendrobium branch, tealeaves, seaweed, Jasmine, ginger and tulip are crushed, be then soaked in water and carried out Ultrasonic vibration and heating are then centrifuged for taking supernatant to obtain plant extracts;
2)Polyethylene alcohol and water is mixed and heated for the first time, titanium dioxide, glycerine, vitamin E, allantoin, egg are subsequently added into Clearly, coconut juice and plant extracts carry out secondary mixing so that stem of noble dendrobium freckle-removing mask is made.
Preferably, in step 1)In, stem of noble dendrobium branch, tealeaves, seaweed, Jasmine, ginger and tulip weight ratio be 50:10-14:20-23:8-13:2-5:7-12.
Preferably, in step 1)In, the average grain diameter of mixture is 0.1-0.3 μm after crushing.
Preferably, in step 1)In, in soaking process, solid-to-liquid ratio 1:5-10.
Preferably, in step 1)In, immersion meets the following conditions:Soaking temperature is 30-40 DEG C, soaking time 6-8h.
Preferably, in step 1)In, the frequency of ultrasonic vibration is 30-40kHz.
Preferably, in step 2)In, the temperature of heating is 80-90 DEG C.
Preferably, in step 2)In, polyvinyl alcohol, water, titanium dioxide, glycerine, vitamin E, allantoin, egg white, coconut juice and The weight ratio of plant extracts is 15:75-85:3-5:5-9:1-3:0.8-1.3:2-4:3-5:10-16.
Preferably, in step 2)In, the time mixed for the first time is 30-40min, and the time of secondary mixing is 2-5h.
The present invention provides a kind of stem of noble dendrobium freckle-removing mask, the stem of noble dendrobium freckle-removing mask is by prepared by above-mentioned preparation method .
Through the above technical solutions, the present invention then carries out hot water leaching first by crushing the plant materials such as stem of noble dendrobium branch Bubble and ultrasonic vibration are then centrifuged for extraction supernatant and obtain extract, then pass through polyvinyl alcohol, titanium dioxide, glycerine, vitamin E, stem of noble dendrobium freckle-removing mask is made in allantoin, egg white, coconut juice and plant extracts, which has whelk excellent Different therapeutic effect, while the preparation method has the advantages that process is simple and raw material is easy to get.
Other features and advantages of the present invention will be described in detail in subsequent specific embodiment part.
Specific implementation mode
The specific implementation mode of the present invention is described in detail below.It should be understood that described herein specific Embodiment is merely to illustrate and explain the present invention, and is not intended to restrict the invention.
The present invention provides a kind of preparation methods of stem of noble dendrobium freckle-removing mask, including:
1)Stem of noble dendrobium branch, tealeaves, seaweed, Jasmine, ginger and tulip are crushed, be then soaked in water and carried out Ultrasonic vibration and heating are then centrifuged for taking supernatant to obtain plant extracts;
2)Polyethylene alcohol and water is mixed and heated for the first time, titanium dioxide, glycerine, vitamin E, allantoin, egg are subsequently added into Clearly, coconut juice and plant extracts carry out secondary mixing so that stem of noble dendrobium freckle-removing mask is made.
In the step 1 of above-mentioned preparation method)In, the materials of each material can select in a wide range, but in order into One step improves the therapeutic effect of stem of noble dendrobium freckle-removing mask, it is preferable that in step 1)In, stem of noble dendrobium branch, tealeaves, seaweed, Jasmine, life The weight ratio of ginger and tulip is 50:10-14:20-23:8-13:2-5:7-12.
In the step 1 of above-mentioned preparation method)In, the average grain diameter of mixture can select in a wide range after crushing, But in order to further increase the therapeutic effect of stem of noble dendrobium freckle-removing mask, it is preferable that in step 1)In, mixture is averaged after crushing Grain size is 0.1-0.3 μm.
In the step 1 of above-mentioned preparation method)In, the dosage of material can select in a wide range in soaking process, but It is to further increase the therapeutic effect of stem of noble dendrobium freckle-removing mask, it is preferable that in step 1)In, in soaking process, solid-to-liquid ratio It is 1:5-10.
In the step 1 of above-mentioned preparation method)In, the condition of immersion can select in a wide range, but in order into one Step improves the therapeutic effect of stem of noble dendrobium freckle-removing mask, it is preferable that in step 1)In, immersion meets the following conditions:Soaking temperature is 30- 40 DEG C, soaking time 6-8h.
In the step 1 of above-mentioned preparation method)In, the condition of ultrasonic vibration can select in a wide range, but in order to Further increase the therapeutic effect of stem of noble dendrobium freckle-removing mask, it is preferable that in step 1)In, the frequency of ultrasonic vibration is 30-40kHz, The temperature of heating is 60-80 DEG C.
In the step 2 of above-mentioned preparation method)In, the condition of heating can select in a wide range, but in order into one Step improves the therapeutic effect of stem of noble dendrobium freckle-removing mask, it is preferable that in step 2)In, the temperature of heating is 80-90 DEG C.
In the step 2 of above-mentioned preparation method)In, the dosage of each material can select in a wide range, but in order into One step improves the therapeutic effect of stem of noble dendrobium freckle-removing mask, it is preferable that in step 2)In, polyvinyl alcohol, water, titanium dioxide, glycerine, dimension life Plain E, allantoin, egg white, coconut juice and plant extracts weight ratio be 15:75-85:3-5:5-9:1-3:0.8-1.3:2-4:3- 5:10-16.
In the step 2 of above-mentioned preparation method)In, mixed condition can select in a wide range, but in order into one Step improves the therapeutic effect of stem of noble dendrobium freckle-removing mask, it is preferable that in step 2)In, the time mixed for the first time is 30-40min, secondary The mixed time is 2-5h.
The present invention provides a kind of stem of noble dendrobium freckle-removing mask, the stem of noble dendrobium freckle-removing mask is by prepared by above-mentioned preparation method .
The present invention will be described in detail by way of examples below.
Embodiment 1
1)By stem of noble dendrobium branch, tealeaves, seaweed, Jasmine, ginger and tulip according to 50:12:21:10:3:10 weight ratio It is 0.2 μm to crush to average grain diameter, is then soaked in water(Solid-to-liquid ratio is 1:8, soaking temperature is 35 DEG C, soaking time For 7h)And carry out ultrasonic vibration(Frequency is 35kHz)And heating(Temperature is 70 DEG C), it is then centrifuged for taking supernatant to obtain plant Extract;
2)Polyethylene alcohol and water is mixed into 35min for the first time and is heated(Temperature is 85 DEG C), be subsequently added into titanium dioxide, glycerine, Vitamin E, allantoin, egg white, coconut juice and plant extracts(Polyvinyl alcohol, water, titanium dioxide, glycerine, vitamin E, allantoin, The weight ratio of egg white, coconut juice and plant extracts is 15:80:4:7:2:1:3:4:13)Secondary mixing 3h is carried out so that the stem of noble dendrobium is made Freckle-removing mask A1.
Embodiment 2
1)By stem of noble dendrobium branch, tealeaves, seaweed, Jasmine, ginger and tulip according to 50:10:20:8:2:7 weight ratio into It is 0.1 μm that row, which is crushed to average grain diameter, is then soaked in water(Solid-to-liquid ratio is 1:5, soaking temperature is 30 DEG C, and soaking time is 6h)And carry out ultrasonic vibration(Frequency is 30kHz)And heating(Temperature is 60 DEG C), it is then centrifuged for that supernatant is taken to carry to obtain plant Take object;
2)Polyethylene alcohol and water is mixed into 30min for the first time and is heated(Temperature is 80 DEG C), be subsequently added into titanium dioxide, glycerine, Vitamin E, allantoin, egg white, coconut juice and plant extracts(Polyvinyl alcohol, water, titanium dioxide, glycerine, vitamin E, allantoin, The weight ratio of egg white, coconut juice and plant extracts is 15:75:3:5:1:0.8:2:3:10)Secondary mixing 2h is carried out so that stone is made Dry measure used in former times freckle-removing mask A2.
Embodiment 3
1)By stem of noble dendrobium branch, tealeaves, seaweed, Jasmine, ginger and tulip according to 50:14:23:13:5:12 weight ratio It is 0.3 μm to crush to average grain diameter, is then soaked in water(Solid-to-liquid ratio is 1:10, soaking temperature is 40 DEG C, soaking time For 8h)And carry out ultrasonic vibration(Frequency is 40kHz)And heating(Temperature is 80 DEG C), it is then centrifuged for taking supernatant to obtain plant Extract;
2)Polyethylene alcohol and water is mixed into 40min for the first time and is heated(Temperature is 90 DEG C), be subsequently added into titanium dioxide, glycerine, Vitamin E, allantoin, egg white, coconut juice and plant extracts(Polyvinyl alcohol, water, titanium dioxide, glycerine, vitamin E, allantoin, The weight ratio of egg white, coconut juice and plant extracts is 15:85:5:9:3:1.3:4:5:16)Secondary mixing 5h is carried out so that stone is made Dry measure used in former times freckle-removing mask A3.
Comparative example 1
The facial mask B1 being prepared Following the procedure of Example 1, unlike, step 2)In be not used plant extracts.
Application examples 1
The patient of 100 freckles, chloasma is selected to use above-mentioned facial mask(Primary, each surface application 20- is used every two days 30min), cure rate then is counted after 3 months and 6 months, concrete outcome is shown in Table 1.
Table 1
The preferred embodiment of the present invention has been described above in detail, still, the tool during present invention is not limited to the embodiments described above Body details can carry out a variety of simple variants, these letters to technical scheme of the present invention within the scope of the technical concept of the present invention Monotropic type all belongs to the scope of protection of the present invention.
It is further to note that specific technical features described in the above specific embodiments, in not lance In the case of shield, can be combined by any suitable means, in order to avoid unnecessary repetition, the present invention to it is various can The combination of energy no longer separately illustrates.
In addition, various embodiments of the present invention can be combined randomly, as long as it is without prejudice to originally The thought of invention, it should also be regarded as the disclosure of the present invention.

Claims (10)

1. a kind of preparation method of stem of noble dendrobium freckle-removing mask, which is characterized in that including:
1)Stem of noble dendrobium branch, tealeaves, seaweed, Jasmine, ginger and tulip are crushed, be then soaked in water and carried out Ultrasonic vibration and heating are then centrifuged for taking supernatant to obtain plant extracts;
2)Polyethylene alcohol and water is mixed and heated for the first time, titanium dioxide, glycerine, vitamin E, allantoin, egg are subsequently added into Clearly, coconut juice and the plant extracts carry out secondary mixing so that the stem of noble dendrobium freckle-removing mask is made.
2. preparation method according to claim 1, wherein in step 1)In, the stem of noble dendrobium branch, tealeaves, seaweed, jasmine The weight ratio of flower, ginger and tulip is 50:10-14:20-23:8-13:2-5:7-12.
3. preparation method according to claim 1, wherein in step 1)In, the average grain diameter of mixture is after crushing 0.1-0.3μm。
4. preparation method according to claim 1, wherein in step 1)In, in the soaking process, solid-to-liquid ratio 1: 5-10。
5. preparation method according to claim 1, wherein in step 1)In, the immersion meets the following conditions:Impregnate temperature Degree is 30-40 DEG C, soaking time 6-8h.
6. preparation method according to claim 1, wherein in step 1)In, the frequency of the ultrasonic vibration is 30- The temperature of 40kHz, the heating are 60-80 DEG C.
7. preparation method according to claim 1, wherein in step 2)In, the temperature of the heating is 80-90 DEG C.
8. preparation method according to claim 1, wherein in step 2)In, it is the polyvinyl alcohol, water, titanium dioxide, sweet Oil, vitamin E, allantoin, egg white, coconut juice and plant extracts weight ratio be 15:75-85:3-5:5-9:1-3:0.8- 1.3:2-4:3-5:10-16.
9. preparation method according to claim 1, wherein in step 2)In, the time mixed for the first time is 30- The time of 40min, the secondary mixing are 2-5h.
10. a kind of stem of noble dendrobium freckle-removing mask, which is characterized in that the stem of noble dendrobium freckle-removing mask passes through any one of claim 1-9 The preparation method is prepared.
CN201810850799.1A 2018-07-29 2018-07-29 Stem of noble dendrobium freckle-removing mask and preparation method thereof Pending CN108567673A (en)

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1506108A (en) * 2002-12-09 2004-06-23 戚海燕 Composite milk powder capable of being eaten and made into beautifying face mask
CN104510638A (en) * 2013-09-27 2015-04-15 青岛锦涟鑫商贸有限公司 Traditional Chinese medicine spot removing mask
CN105125441A (en) * 2015-08-31 2015-12-09 重庆臻意生物科技有限公司 Speckles-removing mask and processing method thereof
CN106474026A (en) * 2015-08-27 2017-03-08 李尧 Freckle-removing mask
CN106511220A (en) * 2016-12-30 2017-03-22 广东国方医药科技有限公司 Dendrobium officinale moisturizing and repair sleeping mask and preparation method thereof
CN106902044A (en) * 2015-12-17 2017-06-30 莫丽艳 A kind of traditional Chinese medicine freckle-removing facial mask

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1506108A (en) * 2002-12-09 2004-06-23 戚海燕 Composite milk powder capable of being eaten and made into beautifying face mask
CN104510638A (en) * 2013-09-27 2015-04-15 青岛锦涟鑫商贸有限公司 Traditional Chinese medicine spot removing mask
CN106474026A (en) * 2015-08-27 2017-03-08 李尧 Freckle-removing mask
CN105125441A (en) * 2015-08-31 2015-12-09 重庆臻意生物科技有限公司 Speckles-removing mask and processing method thereof
CN106902044A (en) * 2015-12-17 2017-06-30 莫丽艳 A kind of traditional Chinese medicine freckle-removing facial mask
CN106511220A (en) * 2016-12-30 2017-03-22 广东国方医药科技有限公司 Dendrobium officinale moisturizing and repair sleeping mask and preparation method thereof

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Application publication date: 20180925