CN105963570A - Traditional Chinese medicine preparation for preventing and alleviating side effect of iodic contrast agent - Google Patents
Traditional Chinese medicine preparation for preventing and alleviating side effect of iodic contrast agent Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine preparation which is specifically applied to clinical examination of medical imaging department, and in particular relates to a traditional Chinese medicine preparation for preventing and alleviating the side effect of an iodic contrast agent. The traditional Chinese medicine preparation is prepared from the following traditional Chinese medicine raw materials in parts by weight: 25 to 30 parts of herba hyperici japonici, 10 to 15 parts of radix cycleae hypoglaucae, 10 to 15 parts of all grass of stellaria neglecta weihe, 10 to 15 parts of herba scutellariae barbatae, 5 to 10 parts of radix ampelopsis, 25 to 30 parts of herba setariae viridis, 10 to 15 parts of herba clerodendranthi spicati, 10 to 15 parts of radix gardenia, 10 to 15 parts of herba inulae salsoloidis, 10 to 15 parts of radix paeoniae rubra and 5 to 10 parts of radix astragali seu hedysari. The traditional Chinese medicine preparation has the advantages that the used traditional Chinese medicines meet the regulations of Pharmacopoeia of China and the medicines are safe and reliable. All the medicines have the effect of preventing or alleviating the side effect caused by the iodic contrast agent in a utilization process or after the utilization, and the traditional Chinese medicine preparation has the characteristics of accurate curative effect, rapid effect, high healing rate, no side effect and the like.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, tool is applied in Medical Imaging Department clinical examination use, and is specifically related to a kind of pre-anti-slow
Solve the Chinese medicine preparation of diodone side effect.
Background technology
Contrast agent is to inject (or taking) to tissue or the chemicals of organ for strengthening Imaging Study effect.These systems
The density of product is higher or lower than surrounding tissue, and the contrast of formation shows image with some apparatus.Operand as conventional in x-ray observation,
Barium sulfate etc..Wherein, the development experience of diodone is from inorganic iodine to organic iodine, from an iodine, diiodo-to triiodo, from ion
Type is to stages such as nonionics.The ionic comonomer contrast agent stable in properties that the 1950's develops, contrast is good, but its
Osmotic pressure is high, and toxicity is bigger.The nonionic with Omnipaque, Ultravist as representative that the eighties in 20th century develops
Monomer contrast agent, is the derivant of Triiodobenzoic acid.It is with the difference of ionic comonomer contrast agent: remove cation, reduces
Infiltration toxicity；Remove carboxyl, reduce neurotoxicity；Add 4～6 hydroxyls, increase hydrophilic, improve water-soluble degree, reduce viscous
Degree and chemical toxicity.It is widely used for heart, angiography and CT enhanced ct scans at present.
In use or also can there is certain side effect after using in diodone, severity of symptom differs, and serious symptom can
Fatal.Process to reaction to determine according to different symptoms and light and heavy degree.General the lighter is not required to process, but wants close observation
Its development, the symptom such as mild nausea, vomiting can be the tendency of severe reaction sometimes.Moderate is reacted such as: vomiting dizzy, serious,
Feel cold, whole body popularity urticaria, face or laryngeal edema, bronchospasm, chest pain out of breath, suffer from abdominal pain, have a headache and limbs are taken out
The reaction anti symptom treatment such as jerk.Severe reaction such as serious collapse, unconsciousness, pulmonary edema, heart stopping collecting or ventricular fibrillation, seriously
Arrhythmia and myocardial infarction etc. must be rescued immediately.Treat based on to the ill, give antiallergic, hormone, spasmolytic boosting
Deng medicine and oxygen therapy, sustain life organ dysfunction.Different contrast agent untoward reaction inequalities, key can identify early, processes
In time.
Summary of the invention
According to above the deficiencies in the prior art, the present invention provides a kind of Chinese medicine preparation preventing to alleviate diodone side effect, it is possible to
The side effect produced in prevention or the in time use of alleviation diodone or after use, its secondary work evident in efficacy, safe and reliable, nontoxic
With, there is wide potential applicability in clinical practice.
A kind of Chinese medicine preparation preventing to alleviate diodone side effect of the present invention, it is characterised in that in parts by weight,
It is prepared from by following raw material of Chinese medicine: Herba Hyperici Japonici 25～30 parts, Radix Ilicis Asprellae rattan 10～15 parts, match Herba stellariae mediae 10～15 parts, Herba Scutellariae Barbatae 10～15
Part, Radix Ampelopsis 5～10 parts, Herba Setariae Viridis 25～30 parts, Herba clerodendranthi spicati 10～15 parts, Flos micheliae Albae root 10～15 parts, Herba Inulae Salsoloidis 10～15
Part, the red Radix Paeoniae Alba 10～15 parts, the Radix Astragali 5～10 parts.
Wherein, preferred version is as follows:
Can be in parts by weight, following raw material of Chinese medicine be prepared from: Herba Hyperici Japonici 25 parts, 10 parts of Radix Ilicis Asprellae rattan, match numerous
10 parts in detail, Herba Scutellariae Barbatae 10 parts, Radix Ampelopsis 5 parts, Herba Setariae Viridis 25 parts, Herba clerodendranthi spicati 10 parts, Flos micheliae Albae root 10 parts, Herba Inulae Salsoloidis
10 parts, the red Radix Paeoniae Alba 10 parts, the Radix Astragali 5 parts.
Can also be in parts by weight, following raw material of Chinese medicine be prepared from: Herba Hyperici Japonici 30 parts, 15 parts of Radix Ilicis Asprellae rattan, match
Herba stellariae mediae 15 parts, Herba Scutellariae Barbatae 15 parts, Radix Ampelopsis 10 parts, Herba Setariae Viridis 30 parts, Herba clerodendranthi spicati 15 parts, Flos micheliae Albae root 15 parts, Sha Xuan
Spend again 15 parts, the red Radix Paeoniae Alba 15 parts, the Radix Astragali 10 parts.
Can also be in parts by weight, following raw material of Chinese medicine be prepared from: Herba Hyperici Japonici 28 parts, 12 parts of Radix Ilicis Asprellae rattan, match
Herba stellariae mediae 12 parts, Herba Scutellariae Barbatae 12 parts, Radix Ampelopsis 8 parts, Herba Setariae Viridis 28 parts, Herba clerodendranthi spicati 12 parts, Flos micheliae Albae root 12 parts, husky Flos Inulae
Spend 12 parts, the red Radix Paeoniae Alba 12 parts, the Radix Astragali 8 parts.
The preparation method of the Chinese medicine preparation of diodone side effect is alleviated in prevention of the present invention, prepares in accordance with the following methods: press
Weigh raw material of Chinese medicine according to formula and join in container, adding water and cover powder immersion 10～20 minutes, added water no powder 3～5
Centimetre, decoct with high heat and use slow fire boiling 20～30 minutes again instead to boiling, take filtrate；Then add water not powder 3～5 lis
Rice, decocts with high heat and uses slow fire boiling 15～20 minutes again instead to boiling, then remove slag and take filtrate, and twice filtrate merges.
When taking, each 300ml, one day twice.
Pharmacology analysis:
Herba Hyperici Japonici: hardship sweet, micro-is cool.Clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, eliminating stasis to stop pain.For hepatitis, early stage liver cirrhosis, door screen
Tail is scorching, eye conjunctivitis, tonsillitis；Furuncle toxic swelling, herpes zoster, venom, traumatic injury are controlled in external.
Radix Ilicis Asprellae rattan: bitter, cold.Return lung, large intestine, Liver Channel.Heat-clearing and toxic substances removing, wind-expelling pain-stopping, relieving stranguria by diuresis.Main anemopyretic cold,
Cough, laryngopharynx swelling and pain, diphtheria, acute toothache, enteritis, dysentery, urinary tract infection and lithangiuria, rheumatalgia, skin infection swell
Poison, venom.
Match Herba stellariae mediae: acid is flat.Removing toxic substances, blood stasis dispelling, heat clearing away, stimulating milk secretion.Cure mainly hemorrhoid, swell and ache, appendicitis, pyretic stranguria, urinary tract sense
Dye.
Herba Scutellariae Barbatae: pungent, bitter, cold.Return lung, liver, kidney channel.Heat-clearing and toxic substances removing, blood stasis dispelling diuresis.For furuncle swelling toxin, swelling throat
Bitterly, venom, fall and flutter the pain of injury, edema, jaundice.
Radix Ampelopsis: bitter, is slightly cold.GUIXIN, stomach warp.Heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation.For carbuncle carbuncle on the back, furuncle, scrofula, water
Burning hot wound.
Herba Setariae Viridis: light, flat.Dispelling pathogenic wind for improving eyesight, clearing away heat and promoting diuresis.For anemopyretic cold, sand holes, conjunctival congestion and pain of eye, icterohepatitis,
Dysuria；Lymphoid tuberculosis is controlled in external.
Herba clerodendranthi spicati: hardship sweet, micro-is cool.Clearing heat and expelling damp, calculus diuresis.For acute and chronic nephritis, cystitis, lithangiuria,
Cholelithiasis.
Flos micheliae Albae root: bitter, pungent, tepor.Removing dampness by means of aromatics, diuresis, relieving cough and resolving phlegm.Cure mainly urinary system infection, dysuria,
Carbuncle.
Herba Inulae Salsoloidis: toil, cool.Heat clearing away, diuresis, removing toxic substances.Control fever caused by exogenous pathogens, dysuria, ulcerative carbuncle toxic swelling, impetigo,
Eczema.
The red Radix Paeoniae Alba: abnormal smells from the patient hardship is put down, nontoxic.Curing mainly pathogen stomachache, except arthralgia due to stagnation of blood, broken heavily fortified point is long-pending, cold and heat, sick tired, and pain relieving, profit is little
Just, QI invigorating.
The Radix Astragali: sweet, temperature.Return lung, spleen channel.Invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.It is weak for the deficiency of vital energy,
Anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and bursts for a long time and does not holds back,
Blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst；Chronic nephritis proteinuria, diabetes.
In medicament composing prescription of the present invention, Herba Hyperici Japonici, Radix Ilicis Asprellae rattan, match Herba stellariae mediae, Herba Scutellariae Barbatae, Radix Ampelopsis heat-clearing and toxic substances removing, alleviate diodone
Toxic and side effects；Herba Setariae Viridis, Herba clerodendranthi spicati, Flos micheliae Albae root, Herba Inulae Salsoloidis diuresis are relieved oedema or abdominal distension through diuresis or purgation, and promote that internal water circulates, and accelerate iodine and make
Shadow agent excretes；The red Radix Paeoniae Alba, Radix Astragali tonifying vital QI, nourish patient's body constitution, improves resistance.
It is an advantage of the current invention that used Chinese medicine meets Pharmacopoeia of People's Republic of China regulation, safety of medicine is reliable.All medicine phases
Prevent or alleviate in time during diodone uses or the side effect of generation after use with playing, there is determined curative effect, instant effect, control
The features such as more rate is high, have no side effect.
Outcome measure:
1, inclusion criteria
Choose patient 50 example through diodone inspection and these patients appearance clinical side effects the most in various degree, wherein, male
24 examples, women 26 example, 33 years old mean age.
2, Therapeutic Method
Take Chinese medicine preparation of the present invention, oral, every day 2 times, the most each 1 time, each 300ml.
3, curative effect judging standard
Cure: the side effect transference cure occurred during diodone uses or after use.
Take a turn for the better: the side effect symptom occurred during diodone uses or after use has improvement.
Invalid: all diseases are without improving.
4, result
Curing 37 examples, take a turn for the better 11 examples, invalid 2 examples, and total effective rate is 96%.
It is exemplified below a model case:
(1) Zhang, women, 32 years old, people from Qingdao.Coming my institute and carry out fallopian tube iodine contrast examination, after inspection, patient goes out
The most slight heating and vomiting phenomenon, and it is attended by sporadic headache, then treat with Chinese medicine preparation of the present invention, take continuously
With two days later, clinical symptoms all disappears, follow-up investigations interior nothing recurrence in a week.
Detailed description of the invention
The present invention will be further described by the following examples.
Embodiment 1:
A kind of Chinese medicine preparation preventing to alleviate diodone side effect, in parts by weight, is prepared from by following raw material of Chinese medicine:
Herba Hyperici Japonici 25 parts, 10 parts of Radix Ilicis Asprellae rattan, match Herba stellariae mediae 10 parts, Herba Scutellariae Barbatae 10 parts, Radix Ampelopsis 5 parts, Herba Setariae Viridis 25 parts, Herba clerodendranthi spicati
10 parts, Flos micheliae Albae root 10 parts, Herba Inulae Salsoloidis 10 parts, the red Radix Paeoniae Alba 10 parts, the Radix Astragali 5 parts.
Embodiment 2:
A kind of Chinese medicine preparation preventing to alleviate diodone side effect, in parts by weight, is prepared from by following raw material of Chinese medicine:
Herba Hyperici Japonici 30 parts, 15 parts of Radix Ilicis Asprellae rattan, match Herba stellariae mediae 15 parts, Herba Scutellariae Barbatae 15 parts, Radix Ampelopsis 10 parts, Herba Setariae Viridis 30 parts, cat's whisker
Grass 15 parts, Flos micheliae Albae root 15 parts, Herba Inulae Salsoloidis 15 parts, the red Radix Paeoniae Alba 15 parts, the Radix Astragali 10 parts.
Embodiment 3:
A kind of Chinese medicine preparation preventing to alleviate diodone side effect, in parts by weight, is prepared from by following raw material of Chinese medicine:
Herba Hyperici Japonici 28 parts, 12 parts of Radix Ilicis Asprellae rattan, match Herba stellariae mediae 12 parts, Herba Scutellariae Barbatae 12 parts, Radix Ampelopsis 8 parts, Herba Setariae Viridis 28 parts, Herba clerodendranthi spicati
12 parts, Flos micheliae Albae root 12 parts, Herba Inulae Salsoloidis 12 parts, the red Radix Paeoniae Alba 12 parts, the Radix Astragali 8 parts.
Embodiment 4:
Embodiment 1～3 is prepared in accordance with the following methods: weighs raw material of Chinese medicine according to formula and joins in container, adding water and cover powder
Soak 20 minutes, added water no powder 5 centimetres, and decocted with high heat and use slow fire boiling again instead 30 minutes to boiling, take filtrate；
Then add water not powder 5 centimetres, with high heat decoct to boiling uses slow fire boiling again instead 20 minutes, then removing slag takes filtrate,
Twice filtrate merges.
When taking, each 300ml, one day twice.
Claims (4)
1. the Chinese medicine preparation preventing to alleviate diodone side effect, it is characterised in that in parts by weight, by following Chinese medicine
Raw material is prepared from: Herba Hyperici Japonici 25～30 parts, Radix Ilicis Asprellae rattan 10～15 parts, match Herba stellariae mediae 10～15 parts, Herba Scutellariae Barbatae 10～15 parts, white
Liana 5～10 parts, Herba Setariae Viridis 25～30 parts, Herba clerodendranthi spicati 10～15 parts, Flos micheliae Albae root 10～15 parts, Herba Inulae Salsoloidis 10～15 parts,
The red Radix Paeoniae Alba 10～15 parts, the Radix Astragali 5～10 parts.
A kind of Chinese medicine preparation preventing to alleviate diodone side effect the most according to claim 1, it is characterised in that according to weight
Amount number meter, is prepared from by following raw material of Chinese medicine: Herba Hyperici Japonici 25 parts, 10 parts of Radix Ilicis Asprellae rattan, match Herba stellariae mediae 10 parts, Herba Scutellariae Barbatae
10 parts, Radix Ampelopsis 5 parts, Herba Setariae Viridis 25 parts, Herba clerodendranthi spicati 10 parts, Flos micheliae Albae root 10 parts, Herba Inulae Salsoloidis 10 parts, the red Radix Paeoniae Alba 10
Part, the Radix Astragali 5 parts.
A kind of Chinese medicine preparation preventing to alleviate diodone side effect the most according to claim 1, it is characterised in that according to weight
Amount number meter, is prepared from by following raw material of Chinese medicine: Herba Hyperici Japonici 30 parts, 15 parts of Radix Ilicis Asprellae rattan, match Herba stellariae mediae 15 parts, Herba Scutellariae Barbatae
15 parts, Radix Ampelopsis 10 parts, Herba Setariae Viridis 30 parts, Herba clerodendranthi spicati 15 parts, Flos micheliae Albae root 15 parts, Herba Inulae Salsoloidis 15 parts, the red Radix Paeoniae Alba
15 parts, the Radix Astragali 10 parts.
A kind of Chinese medicine preparation preventing to alleviate diodone side effect the most according to claim 1, it is characterised in that according to weight
Amount number meter, is prepared from by following raw material of Chinese medicine: Herba Hyperici Japonici 28 parts, 12 parts of Radix Ilicis Asprellae rattan, match Herba stellariae mediae 12 parts, Herba Scutellariae Barbatae
12 parts, Radix Ampelopsis 8 parts, Herba Setariae Viridis 28 parts, Herba clerodendranthi spicati 12 parts, Flos micheliae Albae root 12 parts, Herba Inulae Salsoloidis 12 parts, the red Radix Paeoniae Alba 12
Part, the Radix Astragali 8 parts.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106266731A (en) * | 2016-10-11 | 2017-01-04 | 陈福建 | A kind of image department prevents and alleviates the Chinese medicine composition of contrast agent side effect |
| CN107335066A (en) * | 2017-07-06 | 2017-11-10 | 郝润松 | CT examination enteron aisle contrast medium and preparation method thereof |
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| CN103961587A (en) * | 2014-06-01 | 2014-08-06 | 李纪华 | Traditional Chinese medicinal preparation for treating radiographic contrast nephropathy and preparation method thereof |
| CN105412410A (en) * | 2015-12-17 | 2016-03-23 | 青岛华仁技术孵化器有限公司 | Traditional Chinese medicine preparation for preventing and treating radiographic contrast nephropathy |
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2016
- 2016-06-25 CN CN201610527043.4A patent/CN105963570A/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103961587A (en) * | 2014-06-01 | 2014-08-06 | 李纪华 | Traditional Chinese medicinal preparation for treating radiographic contrast nephropathy and preparation method thereof |
| CN105412410A (en) * | 2015-12-17 | 2016-03-23 | 青岛华仁技术孵化器有限公司 | Traditional Chinese medicine preparation for preventing and treating radiographic contrast nephropathy |
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| CN106266731A (en) * | 2016-10-11 | 2017-01-04 | 陈福建 | A kind of image department prevents and alleviates the Chinese medicine composition of contrast agent side effect |
| CN107335066A (en) * | 2017-07-06 | 2017-11-10 | 郝润松 | CT examination enteron aisle contrast medium and preparation method thereof |
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Application publication date: 20160928 |