CN108567054A - A kind of feed and preparation method thereof and purposes improving laying hen disease resistance - Google Patents

A kind of feed and preparation method thereof and purposes improving laying hen disease resistance Download PDF

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CN108567054A
CN108567054A CN201810441373.0A CN201810441373A CN108567054A CN 108567054 A CN108567054 A CN 108567054A CN 201810441373 A CN201810441373 A CN 201810441373A CN 108567054 A CN108567054 A CN 108567054A
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feed
laying hen
disease resistance
vitamin
laying
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赵鑫
姜文
苏斌朝
张书金
肖俊峰
汤建平
傅心锋
李兵
吴有林
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Hui Nong Bio Tech Ltd Beijing
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/70Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75Feeding-stuffs specially adapted for particular animals for birds for poultry
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/20Animal feeding-stuffs from material of animal origin
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A23K10/37Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from waste material
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/116Heterocyclic compounds
    • A23K20/132Heterocyclic compounds containing only one nitrogen as hetero atom
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/142Amino acids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/158Fatty acids; Fats; Products containing oils or fats
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/174Vitamins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/20Inorganic substances, e.g. oligoelements
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/20Inorganic substances, e.g. oligoelements
    • A23K20/22Compounds of alkali metals
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/20Inorganic substances, e.g. oligoelements
    • A23K20/26Compounds containing phosphorus
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/20Inorganic substances, e.g. oligoelements
    • A23K20/30Oligoelements
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/80Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
    • Y02P60/87Re-use of by-products of food processing for fodder production

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Fodder In General (AREA)
  • Feed For Specific Animals (AREA)

Abstract

The present invention relates to field of fodder, and more particularly to a kind of feed improving laying hen disease resistance and preparation method thereof and purposes.Various raw materials and its weight percent are in the feed:Corn 30%~50%, dregs of beans 10%~25%, rubber seedcake 5%~20%, fly pupa powder 2%~2.5%, Testa Glycines 5%~20%, soybean oil 0.5%~1%, salt 0.2%~0.4%, methionine 0.10%~0.18%, lysine 0.1%~0.3%, calcium monohydrogen phosphate 0.5%~1.2%, mountain flour 6%~9%, sanguinarine 2%~3% and premix 1%~2%.Feed of the present invention in the market has larger gap from the type of primary raw material and ingredient with stage feed, and a kind of new formula is provided for egg feedstuff.Preparation method of the present invention is simple, and feed stability is strong, and condition controllability is good, cheap, has good purposes foreground.

Description

A kind of feed and preparation method thereof and purposes improving laying hen disease resistance
Technical field
The present invention relates to field of fodder, more particularly to a kind of system for the feed and its above-mentioned feed improving laying hen disease resistance Preparation Method and purposes.
Background technology
For laying hen whole life cycle, laying period, is undoubtedly period of greatest concern, exists for culture efficiency Conclusive influence.For many years, base cultivation client is for there are feeding feed stuff structures during Egg Production of Laying Hens single, material quality It is irregular, feed mode is coarse, medication is lack of standardization etc. so that species the advantage developmental retardation is played incomplete or even is reduced, and is led Productivity effect is caused to decline.In addition, summer temp is higher, microbial reproduction is active, easily causes the various alimentary canal class diseases of laying hen. Therefore, the high temperature of summer environment will produce strong influence for Egg Production of Laying Hens level, laying rate decline, egg size is caused to reduce, A series of health factors such as death rate rising, immunity degradation generate.In addition, in recent years, with the fast development of aquaculture, make The prices such as corn, dregs of beans, imported fish meal for feed primary raw material rise steadily, and laying hen production cost increasingly increases, and fish meal In there are various conditionity pathogenic bacteria (newborn salmonella, Escherichia coli etc.), also contain Lizzerosine in some fish meal, cause Dysentery characterized by white mucous stool positive rate increases, and influence is brooded and egg laying performance.
Salpingitis of layer chicken is a kind of common disease of laying hen, and threaten breeding layer chicken industry develop in a healthy way frequently-occurring disease it One, especially easily occur in egg-laying peak.Clinically using oaritis, salpingitis, peritonitis as main feature.Its clinical manifestation Symptom is varied, but to cause laying rate of laying hen to decline, and eggshell quality declines, such as shell egg, soft-shelled egg, husky lime-preserved egg, abnormal Shape egg, white lime-preserved egg, small-sized egg etc. are cardinal symptom.Pouity dwelling place sanitary condition is too poor, cloaca by bacterium (such as Salmonella pullorum, Paratyphosum Bacterium, Escherichia coli etc.) it pollutes and invades fallopian tubal;Or fish meal feeding is excessive, excessive or production double-yolked egg of laying eggs, sometimes Eggshell ruptures in fallopian tubal, damages fallopian tubal;Or be deficient in vitamin in excessive, feed of laying eggs A, D, E etc. can lead to defeated ovum Guan Yan.Poultry suffers from salpingitis, often causes prolapse of fallopian tube, difficult labour etc..
The additive amount of the corn in existing its primary raw material of laying period chicken feed is commonly 60% or more currently on the market, The additive amount of dregs of beans is generally 20% or more, for example, a kind of laying cycle of laying hens cooperation that Chinese patent CN102258153A is provided Feed includes just corn 64-66%, dregs of beans 20-22%, wheat bran 2-4%, steck powder 0.5-1%, cotton dregs 0.4-1%, phytase (5000) 0.1-0.15%, oyster shell whiting 7-10%, mountain flour 1-2%, calcium monohydrogen phosphate 0.5-1%, salt 0.3-1%, 65% bad ammonia Sour 0.2-0.4%, solid methionine 0.1-0.2%, choline chloride 0.06-0.1%, vitamin C 0.3-0.5%, trace element Premix 0.2-0.4%, vitamin premix 0.2-0.4%.Therefore high-quality one kind, safety, low cost are developed, egg can be improved The feed of chicken disease resistance is imperative.
Invention content
For the above-mentioned shortcoming of the prior art, one of the objects of the present invention is to provide a kind of disease-resistant energy of raising laying hen The feed of power, the feed in the market have larger gap with stage feed from the type of primary raw material and ingredient, are Egg feedstuff provides a kind of new formula, and specifically, the feed is with corn, dregs of beans, cottonseed muffin, fly pupa powder, Testa Glycines It is main component with soybean oil, which does not add fish meal, and the content of corn, dregs of beans etc. is greatly reduced, which can expire The basic nutrition demand of sufficient Egg Production of Laying Hens physiology phase has higher feed resource utilization rate, while primary raw material cost is relatively low, comprehensive There is lower production cost for conjunction;By adding sanguinarine, it can cooperate with fly pupa powder and play anti-inflammatory antibacterial effect, Immunity in laying hen body is improved, laying hen disease resistance can be improved, may advantageously facilitate raising industrial sustainable development.
The second object of the present invention is to provide a kind of preparation method of above-mentioned egg feedstuff, and the preparation method is simple, item Part controllability is good, is suitable for industrialized production.
The third object of the present invention is to provide a kind of purposes of above-mentioned egg feedstuff, use it in breeding layer chicken, can Feeding cost is reduced, immunocompetence and antimicrobial antiphlogistic anti-oxidation function of laying hen etc. can be improved, laying hen scale is effectively reduced and supports Grow cost.
The present invention solves its technical problem using following technical scheme to realize:
A kind of feed improving laying hen disease resistance, by weight percentage, including 2%~2.5% fly pupa powder and 2%~ 3% sanguinarine.
Further, the feed further includes:30%~50% corn, 10%~25% dregs of beans, 5%~20% rubber seed Cake and 5%~20% Testa Glycines.
Further, the feed further includes 0.5%~1% soybean oil.
Further, various raw materials and its weight percent are in the feed:Corn 30%~50%, dregs of beans 10%~ 25%, rubber seedcake 5%~20%, fly pupa powder 2%~2.5%, Testa Glycines 5%~20%, soybean oil 0.5%~1%, salt 0.2%~0.4%, methionine 0.10%~0.18%, lysine 0.1%~0.3%, calcium monohydrogen phosphate 0.5%~1.2%, stone Powder 6%~9%, sanguinarine 2%~3% and premix 1%~2%.
Further, various raw materials and its weight percent are in the feed:Corn 40.78%, dregs of beans 14.64%, Rubber seedcake 15%, fly pupa powder 2%, Testa Glycines 15%, soybean oil 1%, salt 0.32%, methionine 0.16%, lysine 0.2%, calcium monohydrogen phosphate 0.98%, mountain flour 6.92%, sanguinarine 2% and premix 1%.
Further, the HPLC purity of the sanguinarine is 98% or more.
Further, the premix provides retinol1 6500IU, vitamin D for every kilogram of feed33300IU, dimension life Plain E200mg, vitamin K33mg, vitamin B11.5mg, vitamin B26.0mg, calcium pantothenate 90mg, niacin 18.0mg, dimension life Plain B63.0mg, vitamin B120.009mg, folic acid 0.6mg, biotin 0.03mg, zinc 35.00mg, copper 4.00mg, iron 60.00mg, manganese 30.00mg, iodine 0.35mg, selenium 0.10mg.
The present invention also provides a kind of preparation methods of the feed of raising laying hen disease resistance, and this method includes following Step, by weight percentage:
1) by 30%~50% corn, 10%~25% dregs of beans, 5%~20% rubber seedcake, 2%~2.5% fly pupa powder, 5%~20% Testa Glycines, 0.5%~1% soybean oil, 0.5%~1.2% calcium monohydrogen phosphate, 6%~9% mountain flour and 1%~2% Premix is sufficiently mixed, and mixture M is made;
2) by 0.2%~0.4% salt, 0.10%~0.18% methionine, 0.1%~0.3% lysine and 2%~ 3% sanguinarine is sufficiently mixed, and mixture N is made;
3) mixture M is added in mixture N, is uniformly mixed.
The present invention also provides the purposes of above-mentioned egg feedstuff, and specifically, feed of the present invention is suitable for laying period Laying hen.Further, feed of the present invention is suitble to apply in the laying hen of 5%~peak phase of laying rate.
Compared with prior art, the invention has the advantages that:
(1) the egg feedstuff addition fly pupa powder in the present invention and sanguinarine, wherein fly pupa powder can improve in laying hen body Immunoglobulin content, to improve immunity of layer chicken, sanguinarine has the content of antimicrobial antiphlogistic effect reduction inflammatory mediator, The two, which cooperates, can play synergistic effect, can improve the disease resistance of laying hen, can be used for preventing or reduce laying hen The incidence of salpingitis.
(2) egg feedstuff of the present invention is main with corn, dregs of beans, rubber seedcake, fly pupa powder, Testa Glycines and soybean oil Raw material is formulated, and compatible use is carried out in proper range, is used with the stage than certain producer in the market from primary raw material Laying hen material primary raw material price reduction 8.5%, the present invention adds mountain flour, calcium monohydrogen phosphate, food on the basis of above-mentioned raw materials Salt, methionine, lysine, premix and sanguinarine obtain feed formula for laying hen of the present invention, experiments verify that, the feeding The daily ration that material formula is fed as laying cycle of laying hens can significantly improve egg size and feedstuff-egg ratio is lower compared with the control group, because This egg feedstuff feed consumption rate is few, is conducive to save feed cost.Compared with the control group, egg shape index and yolk are omited with respect to proportion It is improved, eggshell compares and significantly improves again, can promote egg quality.
(3) preparation method of egg feedstuff of the present invention is simple, and feed stability is strong, and condition controllability is good, and price is low It is honest and clean, there is good application prospect.
Specific implementation mode
The present invention is further described with reference to embodiments, it should be appreciated that these embodiments are not constituted to this hair Bright limitation.
Experimental method in following embodiments is conventional method, raw material involved in the present invention and examination unless otherwise specified Agent is common commercially available product unless otherwise specified, can all be bought and be obtained by market.
Fly pupa powder is powder made of fly pupa, and fly pupa is shunk by not casting off a skin after third instar larvae maturation, is in bucket more Shape, brownish black.Contain the biogenic trace elements of many animals such as Ca, Fe, Cu, Zn, Se, thick egg in fly pupa powder Bai Hanliang is 73.06%, it is necessary to which amino acid (being free of tryptophan) content is 23.06%.The nutrition in laying hen production can be met It needs.Fly pupa larval haemolymph has apparent facilitation in terms of the cellular immunity of enhancing chicken and humoral immune function.
Sanguinarine is a kind of benzene phenanthridines isoquinoline alkaloid, [C of molecular formula20H14N04]+, relative molecular mass 332, Be primarily present in the herb of greater celandine, the root tuber of corydalis, the herb of macleaya cordata, snowpoppy aerial part.With antibacterial, desinsection With anti-inflammatory effect.
Rubber seedcake is the byproduct of rubber seed oil-producing technique, and wherein nutritional ingredient and content is:Moisture 6.1%, thick egg White matter 28.7%, crude fat 9.4%, coarse ash 5.36%, crude fibre 14.6%, calcium 0.24%, phosphorus 0.35%;Linoleic acid (LA) Content is 17mg/g, and leukotrienes (ALA) content is 12mg/g.Eicosapentaenoic acid (EPA) content is 0.1mg/g, 22 carbon Acid (DHA) content is 0.12mg/g;Polyunsaturated fatty acid (PUFA) content is 47mg/g, and n-6PUFA contents are 17mg/ G, n-3PUFA content are 12.6mg/g.
Testa Glycines are the byproducts of soya bean oil-producing technique, mainly the coated substance of soya bean outer layer, color be ecru or It is light yellow, it is peeled or is crushed obtained by two kinds of processing methods of screen by the hot method of fats and oils processing.Its active ingredient and content are:Crude protein 12.31%, crude fat 1.29%, ash content 4.46g, calcium 0.46mg/kg, phosphorus 0.25mg/kg, gross energy 16.27MJ/kg.
Below by way of specific embodiment the technology and feature that the present invention will be described in detail, but these embodiments are not limited to Protection scope of the present invention.
Embodiment 1
A kind of feed improving laying hen disease resistance, various raw materials and its weight percent are in the feed:Corn 30%, dregs of beans 11.32%, rubber seedcake 20%, fly pupa powder 2.5%, Testa Glycines 20%, soybean oil 1.0%, salt 0.4%, egg Propylhomoserin 0.18%, lysine 0.1%, calcium monohydrogen phosphate 0.5%, mountain flour 9%, sanguinarine 3% and premix 2.0%.
Preparation method includes the following steps:
1) corn, dregs of beans, rubber seedcake, Testa Glycines, soybean oil, fly pupa powder, mountain flour, calcium monohydrogen phosphate and premix is abundant Mixture M is made in mixing;
2) salt, methionine, lysine and sanguinarine are sufficiently mixed, mixture N is made;
3) mixture M is added in mixture N, is uniformly mixed to obtain the final product.
Embodiment 2
A kind of feed improving laying hen disease resistance, various raw materials and its weight percent are in the feed:Corn 50%, dregs of beans 25%, rubber seedcake 6.9%, fly pupa powder 2%, Testa Glycines 5%, soybean oil 0.5%, salt 0.2%, methionine 0.1%, lysine 0.1%, calcium monohydrogen phosphate 1.2%, mountain flour 6%, sanguinarine 2% and premix 1%.The same embodiment of preparation method 1。
Embodiment 3
A kind of feed improving laying hen disease resistance, various raw materials and its weight percent are in the feed:Corn 40%, dregs of beans 10%, rubber seedcake 18.25%, fly pupa powder 2.5%, Testa Glycines 15%, soybean oil 0.5%, salt 0.3%, egg Propylhomoserin 0.15%, lysine 0.3%, calcium monohydrogen phosphate 1%, mountain flour 7%, sanguinarine 3% and premix 2%.Preparation method is the same as real Apply example 1.
Embodiment 4
Present embodiment illustrates formula a~d of laying cycle of laying hens feed, the feed includes the original of following weight percent Material, is shown in Table 1
Table 1:The formula composition and nutrient component meter of feed
The preparation method is as in the first embodiment, obtain formula a~d.
Embodiment 5
The blue brown laying hen 150 in sea of 25 week old health similar in weight and laying rate is chosen in experiment, is randomly divided into 5 groups, often 3 repetitions of group, it is each to repeat 10;5 processing groups are respectively:Processing group 1 (to be formulated a as raising daily ration), processing group 2 (to be formulated b as raising daily ration), processing group 3 (to be formulated c as raising daily ration), processing group 4 are (to be formulated d as feeding day Grain), control group.The control group fed laying hen material that certain producer uses with the stage in the market (feed formula is shown in Table 2).Experimental period 60d, Its pre-feeding period 7d.Using confined poultry house, it is freely eaten and drinking-water, force ventilation is freely divulged information, natural lighting adds morning and evening light filling Hen house health is swept in 16h, daily timing, and every 7d cleaning up excrement 1 time, henhouse periodically carries out routine disinfection.Daily feeding 3 times (08: 00、13∶00、19∶00)。
Table 2:Control group laying hen material forms and trophic level
Recorded during experiment egg size, inventory, remaining doses, egg number, livestock on hand chicken number, calculate day egg production, laying rate, Feed intake and feedstuff-egg ratio.20 pieces of random collectings of every group of last 1d egg takes back laboratory weekly, measures egg shape index, yolk, egg Shell phase counterweight.Control group and test group respectively randomly select 10 laying hens, and sampling determination Laying-hen Serum is carried out using blood collection method under the wing IL-2 gene expression amounts in middle IL-2 levels and oviduct tissue, use the reagent purchased from the enzyme-linked bio tech ltd in Shanghai Box measures Immunoglobulin IgA, IgE the and IgG concentration of laying hen using double antibody sandwich method, as a result as shown in table 3-7:
Table 3:Influence of the different disposal group to performance in layers
Note:Compared with the control group, * * indicate difference extremely significantly (P to each processing group<0.01), * indicates significant difference (P< 0.05);Mark person is not then not notable (P>0.05);
As shown in Table 3, processing group laying rate is above control group, but difference is not notable;Egg size, the daily ingestion amount of processing group It is better than control group with feedstuff-egg ratio, and difference reaches the level of signifiance.Illustrate that the feed formula of processing group is used for egg feedstuff feed consumption Amount is few, is conducive to save feed cost.
Table 4:Influence of the different disposal group to Egg Quality
Note:Compared with the control group, * * indicate difference extremely significantly (P to each processing group<0.01), * indicates significant difference (P< 0.05);Mark person is not then not notable (P>0.05);
As shown in Table 4, processing group egg shape index and yolk are slightly improved than control group with respect to proportion, but difference is not shown It writes;Processing group eggshell improves 16.67% with respect to proportion than control group, significant difference.Illustrate that the feed of processing group can be promoted Egg quality.
Table 5:Influence of the different disposal group to immunity
Note:It is analyzed with t methods of inspection, compared with the control group with processing group in a line, * * indicate difference extremely significantly (P< 0.01), * indicates significant difference (P<0.05);Mark person is not then not notable (P>0.05);With a line processing group 3-4 and processing Group 1 is compared, and a indicates difference extremely significantly (P<0.01);
As shown in Table 5, the concentration of the immunoglobulin of processing group 2 compared with the control group, slightly improves but difference is not notable, Illustrate that individually adding sanguinarine has not significant impact the immunity of laying hen;And the immunoglobulin concentrations of processing group 1 with it is right It is compared according to group, difference is extremely notable, illustrates that the immunity of laying hen can be improved by adding fly pupa powder;Processing group 3 and processing group 4 and processing group 1 compares, and difference is extremely notable, illustrates that adding sanguinarine can act synergistically with fly pupa powder, pole significantly increases laying hen body and exempts from Epidemic disease power.
Table 6:Influence of the different disposal group to IL-2 levels in serum
Note:It is analyzed with t methods of inspection, compared with the control group with processing group in a line, * * indicate difference extremely significantly (P< 0.01), * indicates significant difference (P<0.05);Mark person is not then not notable (P>0.05);With a line processing group 3-4 and processing Group 2 is compared, and a indicates difference extremely significantly (P<0.01);
Table 7:The influence of IL-2 gene expressions in laying hen oviduct tissue
Note:It is analyzed with t methods of inspection, compared with the control group with processing group in a line, * * indicate difference extremely significantly (P< 0.01), * indicates significant difference (P<0.05);Mark person is not then not notable (P>0.05);With in a line compared with processing group 2, A indicates difference extremely significantly (P<0.01);
By table 6-7 it is found that IL-2 gene expression amounts are notable in IL-2 levels and oviduct tissue in 2 Laying-hen Serum of processing group Less than control group and processing group 1, there is statistical significance, and IL-2 levels and defeated ovum in 4 Laying-hen Serum of processing group 3 and processing group IL-2 gene expression amounts significantly reduce compared with processing group 2 in tubing, illustrate the water that sanguinarine can make IL-2 in Laying-hen Serum IL-2 gene expression amounts significantly reduce in gentle oviduct tissue, have preferable anti-inflammatory effect, and adding fly pupa powder can reinforce The anti-inflammatory effect of sanguinarine.
Contain from table 5-7 it is found that adding immunoglobulin in fly pupa powder and the Laying-hen Serum of sanguinarine group (processing 3-4) simultaneously Amount is significantly higher than control group, individually addition fly pupa powder group (processing group 1) and individually addition sanguinarine group (processing group 2) (P< 0.05);IL-2 gene expressions in IL-2 levels and oviduct tissue in fly pupa powder and the Laying-hen Serum of sanguinarine group are added simultaneously Amount is substantially less than control group, individually addition fly pupa powder group and individually addition sanguinarine group (P<0.05), illustrate fly pupa powder and red root Both alkali is improving laying hen immunity of organisms, and the content and IL-2 gene expression amount aspects for reducing IL-2 inflammatory factors have collaboration Effect, can effectively improve the disease resistance of laying hen, can be used in the fallopian tubal incidence for preventing or reducing laying hen.
In addition, from the aspect of feed cost, according to current laying hen material primary raw material monovalent (1800 yuan/ton of corn, cotton dregs 3000 yuan/ton, 1600 yuan/ton of Testa Glycines, 5600 yuan/ton of soya-bean oil, 3340 yuan/ton of dregs of beans, 1650 yuan/ton of rubber seedcake, fly pupa 11000 yuan/ton of 9000 yuan/ton of powder and fish meal), calculate separately in the market certain producer with stage laying hen material primary raw material and the present invention Laying hen material primary raw material price, is computed, and control group laying hen material above-mentioned raw materials cost is 2148 yuan/ton, laying hen material master of the present invention It is 1965 yuan/ton to want raw material average unit cost, from the cost of primary raw material, reduces 8.5%.
To sum up, feed of the present invention is fed for laying cycle of laying hens, can improve egg size and feedstuff-egg ratio is lower, therefore Egg feedstuff feed consumption rate is few, is conducive to save feed cost.The quality of produced egg is more excellent compared with control group, in addition, passing through raising The content laying hen immunity of organisms of immunoglobulin in laying hen body, and the content by reducing inflammatory mediator, advantageously reduce The incidence of the defeated hose inflammation of laying hen, the economic value with highly significant.

Claims (10)

1. a kind of feed improving laying hen disease resistance, which is characterized in that by weight percentage, including 2%~2.5% fly pupa Powder and 2%~3% sanguinarine.
2. a kind of feed improving laying hen disease resistance as described in claim 1, which is characterized in that the feed further includes: 30%~50% corn, 10%~25% dregs of beans, 5%~20% rubber seedcake and 5%~20% Testa Glycines.
3. a kind of feed improving laying hen disease resistance as claimed in claim 2, which is characterized in that the feed further includes 0.5%~1% soybean oil.
4. a kind of feed improving laying hen disease resistance as claimed in claim 3, which is characterized in that various originals in the feed Material and its weight percent are:Corn 30%~50%, dregs of beans 10%~25%, rubber seedcake 5%~20%, fly pupa powder 2% ~2.5%, Testa Glycines 5%~20%, soybean oil 0.5%~1%, salt 0.2%~0.4%, methionine 0.10%~ 0.18%, lysine 0.1%~0.3%, calcium monohydrogen phosphate 0.5%~1.2%, mountain flour 6%~9%, sanguinarine 2%~3% and Premix 1%~2%.
5. a kind of feed improving laying hen disease resistance as claimed in claim 4, which is characterized in that various originals in the feed Material and its weight percent are:Corn 40.78%, dregs of beans 14.64%, rubber seedcake 15%, fly pupa powder 2%, Testa Glycines 15%, Soybean oil 1%, salt 0.32%, methionine 0.16%, lysine 0.2%, calcium monohydrogen phosphate 0.98%, mountain flour 6.92%, red root Alkali 2% and premix 1%.
6. a kind of feed improving laying hen disease resistance as described in any one in claim 1-5, which is characterized in that the red root The HPLC purity of alkali is 98% or more.
7. a kind of feed improving laying hen disease resistance as described in claim 4 or 5, which is characterized in that the premix is Retinol1 6500IU, vitamin D are provided per kilogram of feed33300IU, vitamin E2 00mg, vitamin K33mg, vitamin B11.5mg, vitamin B26.0mg, calcium pantothenate 90mg, niacin 18.0mg, vitamin B63.0mg, vitamin B120.009mg, Folic acid 0.6mg, biotin 0.03mg, zinc 35.00mg, copper 4.00mg, iron 60.00mg, manganese 30.00mg, iodine 0.35mg, selenium 0.10mg。
8. a kind of preparation method for the feed improving laying hen disease resistance, which is characterized in that this approach includes the following steps, by weight Measure percentages:
1) by 30%~50% corn, 10%~25% dregs of beans, 5%~20% rubber seedcake, 2%~2.5% fly pupa powder, 5% ~20% Testa Glycines, 0.5%~1% soybean oil, 0.5%~1.2% calcium monohydrogen phosphate, 6%~9% mountain flour and 1%~2% premix Material is sufficiently mixed, and mixture M is made;
2) by 0.2%~0.4% salt, 0.10%~0.18% methionine, 0.1%~0.3% lysine and 2%~3% blood Root alkali is sufficiently mixed, and mixture N is made;
3) mixture M is added in mixture N, is uniformly mixed.
9. claim 1~7 any one of them improves the purposes of the feed of laying hen disease resistance, it is characterised in that:The feeding Expect the application in the laying hen of laying period.
10. purposes as claimed in claim 9, it is characterised in that:The laying period is 5%~peak phase of laying rate.
CN201810441373.0A 2018-05-10 2018-05-10 A kind of feed and preparation method thereof and purposes improving laying hen disease resistance Withdrawn CN108567054A (en)

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