CN108553589A - Capsule with dendrobium stem and preparation method thereof - Google Patents
Capsule with dendrobium stem and preparation method thereof Download PDFInfo
- Publication number
- CN108553589A CN108553589A CN201810598781.7A CN201810598781A CN108553589A CN 108553589 A CN108553589 A CN 108553589A CN 201810598781 A CN201810598781 A CN 201810598781A CN 108553589 A CN108553589 A CN 108553589A
- Authority
- CN
- China
- Prior art keywords
- parts
- dendrobium
- capsule
- stem
- content
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
- A61K36/8984—Dendrobium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/43—Cuscutaceae (Dodder family), e.g. Cuscuta epithymum or greater dodder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/64—Orobanchaceae (Broom-rape family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/69—Polygalaceae (Milkwort family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of capsule with dendrobium stem and preparation method thereof, the content of capsule consists of the following compositions by weight：40~60 parts of stem of Dendrobium, 45~55 parts of Herba Cistanches, 40~55 parts of the fruit of Chinese wolfberry, 45~55 parts of ripe dried rehamnnia root, 40~60 parts of Radix Polygalae, 40~55 parts of Semen Cuscutae, 40~55 parts of teasel root and day 1~3 part of hero.The capsule with dendrobium stem of the present invention has effects that anti-oxidant, raising immunity and inhibits tumour by the coordinative role of each raw material.
Description
Technical field
The present invention relates to a kind of Medicines and Health Products, and in particular to a kind of capsule with dendrobium stem and preparation method thereof.
Background technology
The stem of noble dendrobium is orchid HERBA DENDROBII Dendrobium nobile Lindl., Dendrobium Chrysotoxum Lindl Dendrobium
The cultivation product and its congener of chrysotoxum Lindl. or Dendrobium fimbriatum Hook Den-drobium fimbriatum Hook.
The fresh or dry stem of allied species, is the rare traditional Chinese medicine of medicine-food two-purpose.Contain polysaccharide, alkaloid, amino acid, micro in the stem of noble dendrobium
The active ingredients such as element and luxuriant and rich with fragrance class compound have and improve immunity of organisms, antitumor, anti-oxidant, anti-aging, inhibit blood platelet
Agglutination, expansion blood vessel promote the extensive pharmacological actions such as digestive juice secretion, reducing blood lipid, hypoglycemic and antipyretic analgesic, magical medicine
Effect receives more and more attention and concern.
About dendrobium health-care product, Chinese patent literature CN106309933A（Application number 201510337553.0）It discloses
It is a kind of it is antifatigue, improve immune, sobering-up toxin-eliminating Dendrobium officinale health product, by 40-60 parts of dendrobium candidums, 15-30 parts of trifoliate orange Dulcis,
15-20 parts of pueraria lobatas, 5-10 parts of pearl powders, 5-10 parts of cassia seed compositions.The health products are prepared by processing step below：
(a) dendrobium candidum feedstock processing：Iron-sheet dendrobe fresh product is cleaned, dendrobium candidum stipes is cut into about 6cm, then coarse powder is broken to
The particle of≤0.5cm；Dendrobium candidum raw material is carried out 4 hours later, 90 DEG C of dry sterilization；By the dry former of coarse crushing
Material is put into supersonic jet mill and crushes 10min, obtains the dendrobium candidum ultrafine powder that granularity is 1-75 μm；(b) it selects respectively
With the dry powder of other additives of Dendrobium officinale health product, the dry powder of additive is put into supersonic jet mill and is crushed, is obtained
It is less than 2 μm of additive fine powder to granularity；(c) powder that step (b) obtains is added to the dendrobium officinale powder of step (a) acquisition
In broken product, it is made to be sufficiently mixed, so that the water content that dendrobium candidum crushes product is reduced to 30%, obtain mixed-powder；It (d) will step
Suddenly the mixed-powder that (c) is obtained is granulated, and the low temperature drying processing of 4 hours is first carried out at a temperature of 15-35 DEG C, then will
Mixed-powder after low-temperature treatment is stirred under 10~130 DEG C of prilling temperature in 30~240 minutes granulation times
To be granulated, the granulation product that granularity is less than 300 μm are obtained；(e) the granulation product for obtaining step (d) are at a temperature of 40-60 DEG C
Drying, until moisture content is less than or equal to 8%.
In addition, Chinese patent literature CN 102772672B（Application number 201210303818.1）Disclose a kind of iron sheet stone
Dry measure used in former times ganoderma lucidum capsule, the capsule are by dendrobium candidum feedstock processing, the ultra-fine grinding of dendrobium candidum raw material, ganoderma lucidum raw material superfine powder
Broken, mixing and capsule are filled four steps and are made.Specifically, the capsule is prepared by processing step below：（1）
Dendrobium candidum feedstock processing：The root of dendrobium candidum and stipes are cleaned and dried after spontaneously drying, the dendrobium candidum after drying contains
Water is less than 3%；（2）Dendrobium candidum raw material ultra-fine grinding：Dendrobium candidum stipes is cut into diameter 1cm, then coarse powder is broken to diameter
The particle of≤0.5cm；Dendrobium candidum raw material is carried out 4 hours later, 90 DEG C of dry sterilization；By the dry former of coarse crushing
Material is put into supersonic jet mill and crushes 10min, obtains the dendrobium candidum ultrafine powder that granularity is 1-75 μm；（3）Ganoderma lucidum raw material
Ultra-fine grinding：It takes ganoderma powder to be put into supersonic jet mill crushing, obtains the glossy ganoderma ultra-fine powder that granularity is less than 2 μm；（4）It is mixed
It closes：Glossy ganoderma ultra-fine powder 5kg is weighed, 10kg dendrobium candidum ultrafine powders are first added, is uniformly mixed, is then added in mixed powder again
10kg dendrobium candidum ultrafine powders continue to be uniformly mixed, and obtain ultra-fine powder raw material；（5）Capsule is filled：By ultra-fine powder raw material fill to
In capsule shells, dendrobium candidum ganoderma lucidum capsule is obtained.
107753754 A of Chinese patent literature CN（Application number 201711109043.3）Also disclose that a kind of capsule with dendrobium stem
And its preparation process, capsule with dendrobium stem include 3-7 parts of the stem of noble dendrobium, 13-21 parts of mahonia bealei, piper cubeba 10-20 according to parts by weight
Part, 5-12 parts of citron, 7-25 parts of catechu, 28-36 parts of loquat.
Capsule with dendrobium stem disclosed above is immune, antifatigue etc. with enhancing by the coordinative role each by each raw material
Health-care effect.
Invention content
Technical problem to be solved by the invention is to provide one kind, and there is antioxidant activity, enhancing to be immunized, to tumour cell
There are capsule with dendrobium stem of health-care effects such as inhibiting effect and preparation method thereof.
Realize that the technical solution of the object of the invention is a kind of capsule with dendrobium stem, the content of capsule is by weight by following component
Composition：40~60 parts of stem of Dendrobium, 45~55 parts of Herba Cistanches, 40~55 parts of the fruit of Chinese wolfberry, 45~55 parts of ripe dried rehamnnia root, Radix Polygalae 40~60
Part, 40~55 parts of Semen Cuscutae, 40~55 parts of teasel root and day 1~3 part of hero.
Preferably, the content of capsule consists of the following compositions by weight：45~55 parts of stem of Dendrobium, Herba Cistanches 45
~55 parts, 45~55 parts of the fruit of Chinese wolfberry, 45~55 parts of ripe dried rehamnnia root, 45~60 parts of Radix Polygalae, 45~55 parts of Semen Cuscutae, teasel root 45~55
1~2 part of part and day hero.
Optionally, the content of capsule consists of the following compositions by weight：50 parts of stem of Dendrobium, 50 parts of Herba Cistanches, matrimony vine
50 parts of son, 50 parts of ripe dried rehamnnia root, 50 parts of Radix Polygalae, 50 parts of Semen Cuscutae, 50 parts of teasel root and day 1.5 parts of hero.
A kind of preparation method of capsule with dendrobium stem as described above, it is characterised in that include the following steps：
1. stem of Dendrobium pre-processes：The fresh stem of Dendrobium cut will be plucked to clean, dry, be sliced, be dried for standby.
2. the preparation of content：By the stem of Dendrobium weighed according to prescription, Herba Cistanches, the fruit of Chinese wolfberry, ripe dried rehamnnia root, Radix Polygalae, Tu
Silk, teasel root and day hero mixing simultaneously crush, or crush mixing again respectively；Sieving, sterilizing, it is spare to obtain content.
3. the filling of capsule：By in Contents Fill to capsule shells, capsule with dendrobium stem is obtained.
For step when 2. content prepares, in raw material crushing process, external temperature is no more than 25 DEG C.
The present invention has the effect of positive：（1）In the capsule with dendrobium stem of the present invention, all raw materials are filled in glue after crushing
In softgel shell, in raw material crushing and capsule filling process, external temperature is no more than 25 DEG C, and cleanliness factor, which reaches 300,000 grades of control zones, to be wanted
It asks.Raw material controls temperature when crushing, and keeps bioactivity constant.
（2）The capsule with dendrobium stem of the present invention has anti-oxidant, raising immunity and suppression by the coordinative role of each raw material
The effect of tumour processed.
Specific implementation mode
Capsule with dendrobium stem is to be fitted into the content containing the stem of noble dendrobium in capsule shells according to dosage to obtain.
（Embodiment 1）
The content of the capsule with dendrobium stem of the present embodiment consists of the following compositions by weight：50 parts of stem of Dendrobium, 50 parts of Herba Cistanches, Chinese holly
50 parts of matrimony vine, 50 parts of ripe dried rehamnnia root, 50 parts of Radix Polygalae, 50 parts of Semen Cuscutae, 50 parts of teasel root and day 1.5 parts of hero.Wherein each ingredient is equal
By crushing and processing in powdered.Each component therein is Chinese medicine.
The preparation method of the capsule with dendrobium stem of the present embodiment includes the following steps：
1. stem of Dendrobium pre-processes.The fresh stem of Dendrobium cut will be plucked to be rinsed well with clear water, after moisture dries, cut with Chinese medicine
Piece machine is sliced, and control slice thickness is 0.5~3mm, bakes stem of Dendrobium piece low temperature to dry after slice（Moisture content is less than
3%）, spare.
2. the preparation of content.By 50 parts of the stem of Dendrobium weighed according to prescription, 50 parts of Herba Cistanches, 50 parts of the fruit of Chinese wolfberry, ripe dry
50 parts of glutinous rehmannia, 50 parts of Radix Polygalae, 50 parts of Semen Cuscutae, 50 parts of teasel root and day male 1.5 parts of mixings and being sent into pulverizer crush, mistake
100 mesh sieve, and take the powder below sieve, infra-red drying sterilizing that it is spare to obtain content.
When content prepares, each raw material can also be crushed respectively, then each powder raw material is uniformly mixed and obtains in capsule
It is tolerant.
In raw material crushing process, external temperature is no more than 25 DEG C, and cleanliness factor reaches 300,000 grades of control zones and requires.Raw material is in powder
Temperature is controlled when broken, keeps bioactivity constant.
3. capsule（Gelatin）Filling.
It is filled using capsule board made of organic glass, plate divides upper layer and lower layer, upper layer to have hundreds of holes.First by capsule cap, capsule
Status is opened, and capsule body is inserted into capsule plate holes, is adjusted levels distance, is kept capsule mouth equal with plate face.2. step is prepared
Content medicinal powder is laid on plate face, gently vibrates capsule board, keeps medicinal powder filling uniform.After filling up each capsule, by extra of plate face
Grain cleaning, jacks up capsule body, fitting capsule cap, and taking-up obtains capsule with dendrobium stem.
4. quality examination.Observing capsule appearance, whether surface is smooth, clean and tidy, adhesion, deformation and rupture, no foreign odor.
（Embodiment 2）
The content of the capsule with dendrobium stem of the present embodiment consists of the following compositions by weight：50 parts of stem of Dendrobium, 45 parts of Herba Cistanches, Chinese holly
40 parts of matrimony vine, 50 parts of ripe dried rehamnnia root, 55 parts of Radix Polygalae, 45 parts of Semen Cuscutae, 45 parts of teasel root and day 1 part of hero.
The preparation method is the same as that of Example 1, similarly hereinafter.
（Embodiment 3）
The content of the capsule with dendrobium stem of the present embodiment consists of the following compositions by weight：50 parts of stem of Dendrobium, 55 parts of Herba Cistanches, Chinese holly
55 parts of matrimony vine, 45 parts of ripe dried rehamnnia root, 55 parts of Radix Polygalae, 45 parts of Semen Cuscutae, 45 parts of teasel root and day 2 parts of hero.
（Embodiment 4）
The content of the capsule with dendrobium stem of the present embodiment consists of the following compositions by weight：55 parts of stem of Dendrobium, 50 parts of Herba Cistanches, Chinese holly
50 parts of matrimony vine, 45 parts of ripe dried rehamnnia root, 45 parts of Radix Polygalae, 45 parts of Semen Cuscutae, 45 parts of teasel root and day 2 parts of hero.
（Embodiment 5）
The content of the capsule with dendrobium stem of the present embodiment consists of the following compositions by weight：60 parts of stem of Dendrobium, 40 parts of Herba Cistanches, Chinese holly
50 parts of matrimony vine, 45 parts of ripe dried rehamnnia root, 50 parts of Radix Polygalae, 50 parts of Semen Cuscutae, 40 parts of teasel root and day 3 parts of hero.
（Embodiment 6）
The content of the capsule with dendrobium stem of the present embodiment consists of the following compositions by weight：40 parts of stem of Dendrobium, 55 parts of Herba Cistanches, Chinese holly
55 parts of matrimony vine, 55 parts of ripe dried rehamnnia root, 50 parts of Radix Polygalae, 50 parts of Semen Cuscutae, 50 parts of teasel root and day 1.5 parts of hero.
（Test example）
The capsule with dendrobium stem of Example 1, content is poured out, by the mass ratio 1 of 100g contents and 60 degree of white wine:1 heat carries,
Heat carries twice, for the first time extraction 2 hours, and with degreasing yarn in being filtered on funnel, filter residue remakes second of extraction, 4 hours time, so
After refilter, filtrate merges into extracting solution twice, stands 3, refilters, filtrate is concentrated and is dried in vacuo to obtain extract.
1, extract scavenging ability of DPPH free radical is measured, its antioxidant activity is evaluated.
Experimental result：Removing DPPH free radical IC50 values are 0.086 mg/mL, the experimental results showed that capsule with dendrobium stem extract
With certain antioxidant activity.
2, anti-tumor experiment.
Using mtt assay measure extract to human lung carcinoma cell (A549), human breast cancer cell, cervical cancer cell it is antitumor
Activity；Reference material adriamycin, testing result are as follows：
IC of the extract to tumor cell proliferation50Value
Experimental result shows that extract has certain inhibitory activity to above-mentioned three kinds of cells；Wherein to cervical cancer Hela cells and lung gland
The half-inhibition concentration IC50 of cancer A549 is less than 100 μ g/mL, is more than 100 μ g/ to breast cancer MCF-7 half-inhibition concentrations IC50
mL。
It is enlightenment with above-mentioned desirable embodiment according to the present invention, through the above description, relevant staff is complete
Various changes and amendments can be carried out without departing from the scope of the technological thought of the present invention' entirely.The technology of this invention
Property range is not limited to the contents of the specification, it is necessary to determine its technical scope according to right.
Claims (5)
1. a kind of capsule with dendrobium stem, it is characterised in that the content of capsule consists of the following compositions by weight：Stem of Dendrobium 40~60
Part, 45~55 parts of Herba Cistanches, 40~55 parts of the fruit of Chinese wolfberry, 45~55 parts of ripe dried rehamnnia root, 40~60 parts of Radix Polygalae, Semen Cuscutae 40~55
Part, 40~55 parts of teasel root and day 1~3 part of hero.
2. capsule with dendrobium stem according to claim 1, it is characterised in that the content of capsule is by weight by following component group
At：45~55 parts of stem of Dendrobium, 45~55 parts of Herba Cistanches, 45~55 parts of the fruit of Chinese wolfberry, 45~55 parts of ripe dried rehamnnia root, Radix Polygalae 45~60
Part, 45~55 parts of Semen Cuscutae, 45~55 parts of teasel root and day 1~2 part of hero.
3. capsule with dendrobium stem according to claim 1, it is characterised in that the content of capsule is by weight by following component group
At：50 parts of stem of Dendrobium, 50 parts of Herba Cistanches, 50 parts of the fruit of Chinese wolfberry, 50 parts of ripe dried rehamnnia root, 50 parts of Radix Polygalae, 50 parts of Semen Cuscutae, 50 parts of teasel root
And it is 1.5 parts male.
4. a kind of preparation method of capsule with dendrobium stem as described in claim 1, it is characterised in that include the following steps：
1. stem of Dendrobium pre-processes：The fresh stem of Dendrobium cut will be plucked to clean, dry, be sliced, be dried for standby；
2. the preparation of content：By the stem of Dendrobium weighed according to prescription, Herba Cistanches, the fruit of Chinese wolfberry, ripe dried rehamnnia root, Radix Polygalae, Semen Cuscutae,
Teasel root and day hero mixing simultaneously crush, or crush mixing again respectively；Sieving, sterilizing, it is spare to obtain content；
3. the filling of capsule：By in Contents Fill to capsule shells, capsule with dendrobium stem is obtained.
5. the preparation method of capsule with dendrobium stem according to claim 4, it is characterised in that：Step is former when 2. content prepares
During feed powder is broken, external temperature is no more than 25 DEG C.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810598781.7A CN108553589A (en) | 2018-06-12 | 2018-06-12 | Capsule with dendrobium stem and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810598781.7A CN108553589A (en) | 2018-06-12 | 2018-06-12 | Capsule with dendrobium stem and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108553589A true CN108553589A (en) | 2018-09-21 |
Family
ID=63553366
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810598781.7A Pending CN108553589A (en) | 2018-06-12 | 2018-06-12 | Capsule with dendrobium stem and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108553589A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112156167A (en) * | 2020-10-13 | 2021-01-01 | 安徽霍山县药王谷林农科技有限公司 | Preparation process of dendrobium huoshanense compound Zhenshan Zhenhua Zhenhantan granules |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1840093A (en) * | 2006-01-26 | 2006-10-04 | 葛强 | Compound capsule with dendrobium stem and its preparing method |
| CN102772672A (en) * | 2012-08-24 | 2012-11-14 | 西双版纳增靓生物科技有限公司 | Dendrobium candidum ganoderma lucidum capsule |
| CN106075091A (en) * | 2016-08-15 | 2016-11-09 | 新疆环拓生物科技有限公司 | A kind of healthy medicated wine and preparation method thereof |
-
2018
- 2018-06-12 CN CN201810598781.7A patent/CN108553589A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1840093A (en) * | 2006-01-26 | 2006-10-04 | 葛强 | Compound capsule with dendrobium stem and its preparing method |
| CN102772672A (en) * | 2012-08-24 | 2012-11-14 | 西双版纳增靓生物科技有限公司 | Dendrobium candidum ganoderma lucidum capsule |
| CN106075091A (en) * | 2016-08-15 | 2016-11-09 | 新疆环拓生物科技有限公司 | A kind of healthy medicated wine and preparation method thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112156167A (en) * | 2020-10-13 | 2021-01-01 | 安徽霍山县药王谷林农科技有限公司 | Preparation process of dendrobium huoshanense compound Zhenshan Zhenhua Zhenhantan granules |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101214079B (en) | Barley seedling powder solid beverage and production technology thereof | |
| CN107019718A (en) | A kind of preparation method of Radix Codonopsis broken wall medicine materical crude slice | |
| CN105079046B (en) | A kind of antitumor soft capsule of full ganoderma lucidum and preparation method thereof | |
| CN1754456A (en) | Dual-purpose tortoise tuckahoe serial product as food and medicine, and its preparation method | |
| CN103054922B (en) | Preparation technology of panax pseudoginseng ultrafine powder granular decoction pieces | |
| CN105639659B (en) | Fiber food and preparation method thereof | |
| CN102772444A (en) | Method for processing traditional Chinese medicinal ultramicro wall-broken oral tablet slices | |
| CN102772440A (en) | Processing method of ultra-micro wall-breaking oral-tablet decoction pieces by traditional Chinese medicines | |
| CN1226940C (en) | Royal jelly composition with improved sleep function | |
| CN108553589A (en) | Capsule with dendrobium stem and preparation method thereof | |
| CN107183246A (en) | A kind of fragrance of a flower is calmed the nerves blood-pressure decreasing tea and preparation method thereof | |
| KR20000018849A (en) | Health supplementation foods using cordyceps militaris and production process | |
| CN103535734B (en) | Bagged instant preparation of a kind of improving water flood and preparation method thereof | |
| CN108295132A (en) | The preparation method of sea-buckthorn beauty treatment lozenge | |
| CN105521178B (en) | A kind of soft capsule with aloe and its preparation method and application | |
| CN110115731B (en) | Preparation method of fresh rehmannia root powder and fresh rehmannia root powder decoction pieces | |
| CN107362234A (en) | It is a kind of to treat hypertension on behalf of the tea | |
| CN104800273A (en) | Medicinal preparation for treating arthralgia, and preparation method thereof | |
| CN104547071B (en) | Preparation method of bezoar detoxifying film coated tablet | |
| CN102772445A (en) | Method for processing traditional Chinese medicinal ultramicro wall-broken oral liquid slices | |
| CN102772437A (en) | Processing method of ultra-micro wall-breaking oral liquid-preparation decoction pieces by traditional Chinese medicines | |
| CN102772441A (en) | Method for processing traditional Chinese medicinal ultramicro wall-broken capsule slices | |
| KR102255977B1 (en) | Method for Preparing Pills Comprising Ginseng | |
| KR101347516B1 (en) | Method of preparing Gyoungokgo and Gyoungokgo prepared thereby | |
| CN107951989A (en) | A kind of method moulded preparation method and prepare shenmai rehmannia pill |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20180921 |