CN108531338A - A kind of feedstock composition that health-care wine is made, its health-care wine are made and preparation method thereof - Google Patents

A kind of feedstock composition that health-care wine is made, its health-care wine are made and preparation method thereof Download PDF

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CN108531338A
CN108531338A CN201810573741.7A CN201810573741A CN108531338A CN 108531338 A CN108531338 A CN 108531338A CN 201810573741 A CN201810573741 A CN 201810573741A CN 108531338 A CN108531338 A CN 108531338A
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wine
health
chinese medicine
radix
medicine composition
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张希春
李青山
胡会玲
宋毓晔
穆树荷
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Shanxi University of Chinese Mediciine
Shanxi University of Traditional Chinese Mediciine
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    • C12GWINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
    • C12G3/00Preparation of other alcoholic beverages
    • C12G3/04Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/758Zanthoxylum, e.g. pricklyash
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12GWINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
    • C12G3/00Preparation of other alcoholic beverages
    • C12G3/02Preparation of other alcoholic beverages by fermentation

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Abstract

Made the present invention relates to a kind of feedstock composition of health-care wine wine, its health-care wine and preparation method thereof, including former wine material and Chinese medicine composition;The quality proportioning of the former wine material and the Chinese medicine composition is 10: 3;The former wine material includes:Milled glutinous broomcorn millet and maize;The Chinese medicine composition includes:Radix Astragali, Radix Codonopsis, Radix Glycyrrhizae, Chinese prickly ash and rhizoma zingiberis;Wherein, the quality proportioning of milled glutinous broomcorn millet and maize is 4: 1;Wherein, Chinese medicine composition includes according to the mass fraction:Radix Astragali 7.3 12.6, Radix Codonopsis 7.8 13.5, Radix Glycyrrhizae 4.8 7.2, Chinese prickly ash 0.5 4.4 and rhizoma zingiberis 2.7 5.6.Feedstock composition that a kind of health-care wine provided by the invention is made, its health-care wine are made and preparation method thereof, have simple for process, are easy to industrialization, ecological, environmental protective, edible safety has fill temperature sun, tonifying middle-Jiao and Qi, beneficial spleen and stomach, the advantageous effect of support kidney qi.

Description

A kind of feedstock composition that health-care wine is made, its health-care wine are made and preparation method thereof
Technical field
The invention belongs to the material combinations that the applied technical field of natural active matter more particularly to a kind of health-care wine are made Object, its health-care wine wine and preparation method thereof.
Background technology
The present invention is originated from《The universal love heart reflects》Bao Yuan Tang, former prescription taste includes Radix Astragali, ginseng, Chinese cassia tree, Radix Glycyrrhizae.《Cure ancestor's gold Jian Shanbuming hospital opinion is a roll of》:" control total side of male woman's deficiency of vital energy.Baby shies timid, acne man void person, most preferably." usage is:It is " right Four tastes, are decocted in water for oral dose." to be put into be both food and the article list of drug.Bao Yuan Tang fill temperature sun, is suitable for deficient labor Timid, insufficiency of primordial QI or lassitude hypodynamia, few gas chilly or children's's variola, deficiency of yang top are fallen into or deficiency of blood slurry is clear, cannot initiate to be in the milk. And, traditional prescription of function brilliance, Bao Yuan Tang need to be deeply developed, to give full play to its warming YANG and invigorating QI as a kind of mild in medicine property Benefiting action, serve people's health.
Invention content
(1) technical problems to be solved
For existing technical problem, the present invention provides feedstock composition, its health-care wine that a kind of health-care wine is made and makes And preparation method thereof, at low cost, the strong advantageous effect of effect.
(2) technical solution
In order to achieve the above object, the main technical schemes that the present invention uses include:
A kind of feedstock composition that health-care wine is made, including former wine material and Chinese medicine composition;
The quality proportioning of the former wine material and the Chinese medicine composition is 10: 3;
The former wine material includes:Milled glutinous broomcorn millet and maize;
The Chinese medicine composition includes:Radix Astragali, Radix Codonopsis, Radix Glycyrrhizae, Chinese prickly ash and rhizoma zingiberis;
Wherein, the quality proportioning of milled glutinous broomcorn millet and maize is 4: 1;
Wherein, Chinese medicine composition includes according to the mass fraction:Radix Astragali 7.3-12.6, Radix Codonopsis 7.8-13.5, Radix Glycyrrhizae 4.8- 7.2, Chinese prickly ash 0.5-4.4 and rhizoma zingiberis 2.7-5.6.
Preferably, according to the mass fraction, Chinese medicine composition includes following raw material:
Radix Astragali 9, Radix Codonopsis 9, Radix Glycyrrhizae 6, Chinese prickly ash 2 and rhizoma zingiberis 4.
The technical program also provides a kind of method that sharp above-mentioned raw materials composition prepares health-care wine wine, includes the following steps:
S1, raw material is chosen:Choose milled glutinous broomcorn millet 75-85, maize 15-25, Radix Astragali 7.3-12.6, Radix Codonopsis 7.8-13.5, Radix Glycyrrhizae 4.8-7.2, Chinese prickly ash 0.5-4.4 and rhizoma zingiberis 2.7-5.6;
S2, former wine is prepared:The milled glutinous broomcorn millet of selection and maize are made into obtain former wine using wine-making technology;
S3, encapsulation Chinese medicine:The Radix Astragali of selection, Radix Codonopsis, Radix Glycyrrhizae, Chinese prickly ash and rhizoma zingiberis are encapsulated into bag, Chinese herbal medicine bag is obtained;
S4, Chinese medicine is decocted:Then by the Chinese herbal medicine bag of acquisition be placed in former wine in, and by former wine and Chinese herbal medicine bag be sealed in 80 DEG C- 0.5h-1h is decocted at 100 DEG C, is obtained health-care wine and is made.
Preferably, use wheat koji as the distiller's yeast for preparing former wine in step s 2.
Preferably, after step s4, the health-care wine of acquisition wine is dispensed, and carries out pasteurization, obtained final Product.
The technical program also provides a kind of using health-care wine wine made from the above method.
(3) advantageous effect
The beneficial effects of the invention are as follows:The present invention provide it is a kind of complain the feedstock composition of fermented glutinous rice, its health-care wine make and its Preparation method at least has following advantageous effects:
1, it is sealed and is decocted using fermented glutinous rice, while raw material is by being both food and the integration of drinking and medicinal herbs object of drug forms, not only Strengthen the healthcare function of product, moreover it is possible to ensure the edible safety of product.
2, preferred Shanxi genunie medicinal materials and Ways of Special Agricultural Products in the making of product ensure to retain local agricultural production while drug effect The traditional properties of product processed food.
3, using fermented glutinous rice, decocting herb composition realizes Chinese medicine composition compared with traditional water decoction method under air-proof condition With merging for food.
4, technical process has solid theory and practice basis, and simple and practicable, is easy to industrialization production.
5, cost reduction, drug effect enhancing.
6, this is simple for process, is easy to industrialization, ecological, environmental protective, edible safety, have fill temperature sun, tonifying middle-Jiao and Qi, benefit spleen and The function of stomach, support kidney qi.
Specific implementation mode
In order to preferably explain the present invention, in order to understand, by detailed description below, present invention work is retouched in detail It states.
Present invention relates particularly to the making that the integration of drinking and medicinal herbs composition in background technology is combined with milled glutinous broomcorn millet and maize fermented glutinous rice Technique, described in milled glutinous broomcorn millet and maize be Shanxi Ways of Special Agricultural Products, have long processing and utilization history.Milled glutinous broomcorn millet is northern China The distinctive kind in area, quality surely belong to the best of In North of Shanxi Province area.Flour is made in milled glutinous broomcorn millet by the local civil common people, then is made Fried cake, for local most distinctive traditional properties food.In addition to this, the best raw material of milled glutinous broomcorn millet or yellow rice wine brewage.《Drink meals Just》Say milled glutinous broomcorn millet nature and flavor:" sweet and neutral, it is nontoxic." tonifying middle-Jiao and Qi of milled glutinous broomcorn millet energy, beneficial spleen and stomach, relieving mental strain and helping sleep, antidiarrheal, black hair.It is applicable in , polydipsia inverse in cough, cholera, stomachache, do not feel like eating, cough due to deficiency of the lung, scald etc..《Mingyi Bielu》Described in:Red milled glutinous broomcorn millet, main cough Inverse, cholera, stopping leak remove heat, only polydipsia.Maize is the seed of gramineous herbaceous plant grain, decladding, that is, millet.It is sweet in flavor, salty, property It is cool, can Energy benefit taste, support kidney qi, relieving restlessness heat, diuresis, can be used for taste abnormal heat, gastric disorder causing nausea vomiting or insufficiency of the spleen diarrhoea, dysphoria with smothery sensation quenches one's thirst, Dry and bladder heat stagnation, difficult urination etc..It is original that millet gruel, the milled congee of people's eating, which are with maize, in Shanxi Province Material is cooked.
Guarantor's meta function of Chinese medicine composition is combined by the present invention with the tonifying middle-Jiao and Qi function of milled glutinous broomcorn millet, maize, utilizes milled glutinous broomcorn millet It decocts a drug wrapped under air-proof condition Chinese medicine composition with maize fermented glutinous rice, compared with traditional water decoction method, drug composition and food in the implementation Fusion simultaneously, improve the acquisition effect of active material, there is feasible actual application value.《Yizong Jinjian》By Bao Yuan Tang:" it is With Huang Qi Bao, the gas of all, Radix Glycyrrhizae protect the gas of all in outside for side, and ginseng protects upper, middle and lower, the inside and outside gas of all, and all gas is controlled And it is enough for vigour.This right soup mends the essential substances from water and cereals day after tomorrow and then has a surplus, and the gas of the raw congenital gate of vitality is then insufficient, adds Chinese cassia tree and is moved between kidney with rousing Gas, this is standby ear." present invention milled glutinous broomcorn millet and maize, the function that Bao Yuan Tang mends the essential substances from water and cereals day after tomorrow can be enhanced, cerealose in fermented glutinous rice Sugar caused by changing not only plays the role of seasoning, moreover it is possible to invigorating spleen and reinforcing stomach together with Radix Glycyrrhizae.A small amount of wine is then assisted with Chinese prickly ash, rhizoma zingiberis Together, interrenal qi can be agitated, the gas of the congenital gate of vitality is enriched.Chinese medicine composition is decocted a drug wrapped using milled glutinous broomcorn millet, the sealing of maize fermented glutinous rice and is made Speciality Foods be full of glycol without the bitterness of general Chinese medicine, be a kind of while having the function of help and food color, smell and taste sense Feel the daily use food of performance.
The present invention exhausts the compound method progress modeling duplication of method, three factor of starvation method by designing with rheum officinale method, swimming power Deficiency of vital energy mouse model.New Chinese medicine composition is orally ingested, and is measured the cold resistant ability of mouse, anti-fatigue ability, blood routine and is referred to Mark and immunocompetence, it was demonstrated that new Chinese medicine composition has effects that QI invigorating temperature is positive, and with original side with suitable effect or Effect enhances.
Present embodiment discloses the feedstock compositions that a kind of health-care wine is made, including former wine material and Chinese medicine composition;
The quality proportioning of the former wine material and the Chinese medicine composition is 10: 3;
The former wine material includes:Milled glutinous broomcorn millet and maize;
The Chinese medicine composition includes:Radix Astragali, Radix Codonopsis, Radix Glycyrrhizae, Chinese prickly ash and rhizoma zingiberis;
Wherein, the quality proportioning of milled glutinous broomcorn millet and maize is 4: 1;
Wherein, Chinese medicine composition includes according to the mass fraction:Radix Astragali 7.3-12.6, Radix Codonopsis 7.8-13.5, Radix Glycyrrhizae 4.8- 7.2, Chinese prickly ash 0.5-4.4 and rhizoma zingiberis 2.7-5.6.
Embodiment
Embodiment 1
It is described in detail below the present embodiment provides a kind of method that health-care wine is made:
Prepare the raw material of following middle parts by weight:Radix Astragali 7.3g, Radix Codonopsis 7.8g, Radix Glycyrrhizae 4.8g, Chinese prickly ash 0.5g/ rhizoma zingiberis 2.7g, Milled glutinous broomcorn millet 75g and maize 15g.
In detail, include the following steps:
S1, raw material is chosen:Choose milled glutinous broomcorn millet 75g, maize 15g, Radix Astragali 7.3g, Radix Codonopsis 7.8g, Radix Glycyrrhizae 4.8g, Chinese prickly ash 0.5g and Rhizoma zingiberis 2.7g;
S2, former wine is prepared:The milled glutinous broomcorn millet of selection and maize are made into obtain former wine using wine-making technology;
S3, encapsulation Chinese medicine:The Radix Astragali of selection, Radix Codonopsis, Radix Glycyrrhizae, Chinese prickly ash and rhizoma zingiberis are encapsulated into bag, Chinese herbal medicine bag is obtained;
S4, Chinese medicine is decocted:Then the Chinese herbal medicine bag of acquisition is placed in former wine, and former wine and Chinese herbal medicine bag is sealed in 80 DEG C of g Under decoct 0.5h, obtain health-care wine and make.
Use wheat koji as the distiller's yeast for preparing former wine in step s 2 in the present embodiment.
In the present embodiment after step s4, the health-care wine of acquisition wine is dispensed, and carries out pasteurization, obtained most Whole product.
The present embodiment is also disclosed a kind of using health-care wine wine made from the above method.
Embodiment 2
It is described in detail below the present embodiment provides a kind of method that health-care wine is made:
Prepare the raw material of following middle parts by weight:Radix Astragali 12.6g, Radix Codonopsis 13.5g, Radix Glycyrrhizae 7.2g, Chinese prickly ash 4.4g, rhizoma zingiberis 5.6g, milled glutinous broomcorn millet 85g and maize 25g.
In detail, include the following steps:
S1, raw material is chosen:Choose milled glutinous broomcorn millet 85g, maize 25g, Radix Astragali 12.6g, Radix Codonopsis 13.5g, Radix Glycyrrhizae 7.2g, Chinese prickly ash 4.4g With rhizoma zingiberis 5.6g;
S2, former wine is prepared:The milled glutinous broomcorn millet of selection and maize are made into obtain former wine using wine-making technology;
S3, encapsulation Chinese medicine:The Radix Astragali of selection, Radix Codonopsis, Radix Glycyrrhizae, Chinese prickly ash and rhizoma zingiberis are encapsulated into bag, Chinese herbal medicine bag is obtained;
S4, Chinese medicine is decocted:Then the Chinese herbal medicine bag of acquisition is placed in former wine, and former wine and Chinese herbal medicine bag is sealed in 100 DEG C Under decoct 1h, obtain health-care wine and make.
Use wheat koji as the distiller's yeast for preparing former wine in step s 2 in the present embodiment.
In the present embodiment after step s4, the health-care wine of acquisition wine is dispensed, and carries out pasteurization, obtained most Whole product.
The present embodiment is also disclosed a kind of using health-care wine wine made from the above method.
Embodiment 3
It is described in detail below the present embodiment provides a kind of method that health-care wine is made:
Prepare the raw material of following middle parts by weight:Radix Astragali 9g, Radix Codonopsis 9g, Radix Glycyrrhizae 6g, Chinese prickly ash 2g, rhizoma zingiberis 4g, milled glutinous broomcorn millet 80g and grain Rice 20g.
In detail, include the following steps:
S1, raw material is chosen:Choose milled glutinous broomcorn millet 80g, maize 20g, Radix Astragali 9g, Radix Codonopsis 9g, Radix Glycyrrhizae 6g, Chinese prickly ash 2g and rhizoma zingiberis 4g;
S2, former wine is prepared:The milled glutinous broomcorn millet of selection and maize are made into obtain former wine using wine-making technology;
S3, encapsulation Chinese medicine:The Radix Astragali of selection, Radix Codonopsis, Radix Glycyrrhizae, Chinese prickly ash and rhizoma zingiberis are encapsulated into bag, Chinese herbal medicine bag is obtained;
S4, Chinese medicine is decocted:Then the Chinese herbal medicine bag of acquisition is placed in former wine, and former wine and Chinese herbal medicine bag is sealed at 95 DEG C 0.8h is decocted, health-care wine is obtained and makes.
Use wheat koji as the distiller's yeast for preparing former wine in step s 2 in the present embodiment.
In the present embodiment after step s4, the health-care wine of acquisition wine is dispensed, and carries out pasteurization, obtained most Whole product.
The present embodiment is also disclosed a kind of using health-care wine wine made from the above method.
Test example
Following animal experiment is carried out with the product obtained in case study on implementation 1-3:(below with this reality of new Chinese medicine composition acute pyogenic infection of finger tip Apply the product obtained in a 1-3)
1, animal packet, raise and establish model of qi-asthenia
1.1, animal packet
SPF grades of healthy male Kunming strain mices 120 are selected, weight is 18~22 grams, and university of TCM tests by Shanxi Animal center provides, experimental animal production licence number:SCXK (Shanxi) 2016-0002, Quality of Experimental Animals quality certification number: 0081670.Mouse adaptability is raised one week before experiment, 22 ± 2 DEG C, relative humidity 40%-60% of room temperature, and light and shade replaces 12h.Institute There is mouse that box is divided to raise, 8/box, free water, standard feed is freely eaten.Mouse adaptability swimming exercise before experiment starts 4d, 5min/d, depth of water 50cm, 25 1 DEG C of soil of water temperature.Experiment meets People's Republic of China's science and technology to the processing method of animal What portion issued《Guiding opinion about kind treatment experimental animal》.
Experiment Jian the previous days beginning carry out negative weight power to mouse and exhaust swimming, and swimming time, rejecting power exhaust record for the first time The mouse that swimming time differs greatly, fasting is for 24 hours.Experiment is weighed on the day of starting, and rejects the larger mouse of weight differences, sieve The male ICR mouse 96 for meeting requirement of experiment is selected, 4 groups, including Normal group, model control group, original side are randomly divided into Control group, new Chinese medicine composition group.Every 24 are one group, 8 box raisings.
1.2 model of qi-asthenia are established
In addition to normal group, remaining 3 groups exhaust the compound method of method, three factor of starvation method with rheum officinale method, swimming power and carry out 9 Its modeling replicates deficiency of vital energy mouse model.The daily morning gavages the rheum officinale decocting liquid of 1g/mL with 20g/kgbw, will move daily afternoon Object bears a heavy burden is put into the 50cm depth of waters, 20 DEG C of water temperature (in the fuse that mouse tail root winding mass 10% is the mouse weight) Sink went swimming is exhausted for degree (mouse nose does not have upstream face 10 seconds) with power, once a day, is kept on a diet simultaneously, and daily 8: 00am, which gives, to be eaten, and 8:00pm removes food.
Mouse behavior is observed, spirit is good always in the entire experiment process for Normal group, agile strong, ingests Normally, stool forming, fur is closely glossy, clings to the body, and body flesh is healthy and strong.Compound modeling group mouse experiment has no bright on the 3rd day Aobvious abnormal, only tail portion fur, which has, slightly soaks;To the 5th day, there is irritated performance in mouse, easily enrages, happiness is baited, and weight is slightly for experiment It reduces, area increase is soaked in tail portion;Experiment was to the 9th day, and mouse agitation fades away, tired mind, and activity is reduced, and hogback is thermophilic It sleeps, difficulty in opening the eyes, the sparse deficient gloss of fur, big-eared under ear, nose color is red, and pawl color is light, soft stool, weight loss, and appetite declines, body Type is thin and weak, and fugue reaction reduces, the deficiency of vital energys symptom such as insensitive to food, prompts modeling success.Claim before modeling, after modeling Each group weight is taken, the variable value of weight is calculated, exhausts method through rheum officinale method, swimming power, three factor complex method of starvation method is multiple The deficiency of vital energy mouse model weight of system is substantially reduced, statistically significant compared with before modeling (P < 0.01) (table 1).
Before and after 1 modeling of table mouse weight comparison ()
*, compared with before modeling, mouse weight is substantially reduced (P < 0.01).
1.3 Chinese medicine compositions feed experiment
It is taken in terms of 2g medicinal materials per kg body weight by adult (60kg), calculating mouse dose is 25g/kgbw.This experiment is adopted The mode for feeding drug containing feed is taken to be administered, administration group animal feed is equivalent to the crude drug of 250g per kg chemical contents.
Animal is divided into 4 groups.1) Normal group, conventinal breeding give standard particle feed, and drinking-water is unlimited;2) model pair According to group, after above-mentioned modeling method modeling success, the daily fixed period with standard particle forage feed, continuous 12 days;3) original side Control group, after above-mentioned modeling method modeling success, the daily fixed period to contain original side's Chinese medicine group forage feed, continuous 12 days; 4) new Chinese medicine composition group, after above modeling method modeling success, the daily fixed period is fed with containing new Chinese medicine composition feed It supports, continuous 12 days.
2 results and analysis
2.1 mouse behaviors
Normal group mouse behavior expression is normal, and expression is quiet, and activity is sensitive, and fur is pure white glossy, and eyes have god, Muffle, ear pale, stool forming, weight increase with food ration and are increased.Model control group and each intervention group were through modeling in 9 days Afterwards, there is tired mind in mouse, and activity is reduced, and hogback is drowsiness, difficulty in opening the eyes, the sparse deficient gloss of fur, and big-eared under ear, color is red, Pawl color is light, soft stool, weight loss, and appetite declines, and build is thin and weak, and fugue reaction reduces, insensitive to food.It is right through original side After intervening 12 days according to group and new Chinese medicine composition, difficulty in opening the eyes is alleviated, and mouse activity is increased, but be slightly less than it is normal right According to group.
The cold survival rate of 2.2 hardies
By 12 days differences feed, Normal group, medicine group mouse tolerance to cold be apparently higher than model of qi-asthenia group; Original side's control group, new Chinese medicine composition group reduce the death rate (P < 0.01) of mouse at low temperatures, but original side's control group No significant difference (P is compared with new Chinese medicine composition group>0.05) (table 2).Show that new Chinese medicine composition has enhancing hardy Cold effect, and it is suitable with original side's effect.
The cold percentage survival of 2 hardy of table
* significantly reduces the death rate (P < 0.01) of mouse at low temperatures compared with model group.
2.3 mouse anti-reflecting fatigue the performance test results
2.3.1 to the influence of Qi deficiency physique mouse swimming time
After difference in 12 days is fed, the 13rd day sheet lead that mouse tail is fixed to its weight 6% is put in diameter about 18cm, Depth of water 18cm in the container that 25 DEG C of water temperature, is swum with mouse and gos deep into the end that do not refloat in 10 seconds in water, record mouse trip to head It swims the time.Qi deficiency physique is most important to show as fatigue, and the most direct and most objective performance of fatigue is the decline of exercise tolerance, institute With using swimming time as the important indicator of reflection exercise tolerance.
Compared with Normal group, model of qi-asthenia group mouse swimming time pole conspicuousness reduces (P < 0.01);With deficiency of vital energy mould Type group is compared, and pole conspicuousness increases (P < 0.01) when original side's control group, new Chinese medicine composition group mouse are swum;Original side compares Group is compared with new Chinese medicine composition group, and mouse swimming time is without significant difference (P>0.05) (table 3).Show new Chinese medicine composition tool There is the ability of enhancing mouse anti-reflecting fatigue, and suitable with original side's effect.
3 each group mouse swimming time of table comparison ()
*, compared with model group, difference is extremely significantly (P < 0.01).
2.3.2 hepatic glycogen and LDH activity
Fatigue is since the bulk deposition of lactic acid causes, and lactic acid is in notable negative correlation in the accumulation of muscle part and muscular strength, LDH activity increases the removing that can accelerate lactic acid.After differences in 12 days are fed, model control group and Normal group ratio Compared with pole, which occur, in hepatic glycogen, LDH activity significantly reduces (P < 0.01);Original side's control group, new Chinese medicine composition group and normal control Group compares, and hepatic glycogen, LDH activity significantly increase (P < 0.01);New Chinese medicine composition group is compared with original side's control group, glycogen Former, LDH activity there are no significant difference (P>0.05) (table 4).Show that new Chinese medicine composition has enhancing mouse anti-reflecting fatigue ability Effect, it is more suitable than original side's effect.
4 mouse hepatic glycogen of table, Serum LDH expression activitiy (n=8,)
Different letters indicate difference extremely significantly (P < 0.01).
The variation of 2.4 mouse GLU, TG, TC, HLD-C, LDL-C
Model control group compared with Normal group, mouse blood sugar pole conspicuousness increase (P < 0.01), TG, TC, HLD-C, There was no significant difference by LDL-C (P > 0.05), and hints model meets requirement of experiment;Original side's control group, new Chinese medicine composition group with just Normal control group compares, and mouse blood sugar is without significant difference (P>0.05), but conspicuousness is less than model control group (P < 0.01);In new Drug composition group and original side's control group compare, and mouse blood sugar significantly reduces (P < 0.01) (table 5).Show new Chinese medicine composition group Have the function of can conspicuousness reduce Qi deficiency physique mouse blood sugar to normal level, and it is higher than original side's effect.
5 mouse GLU, TG, TC, HDL-C, LDL-C variation of table (n=8,)
*, compared with model group, difference is extremely significantly (P < 0.01).
2.5 Qi deficiency physique mouse spleen indexes, thymus index
After differences in 12 days are fed, for model control group compared with Normal group, mouse spleen index, thymus index are aobvious Work property reduces (P < 0.01), and hints model control group mice immune function reduces;Original side's control group, new Chinese medicine composition group with Normal group compares, and the equal conspicuousness of mouse spleen index, thymus index increases (P < 0.01);New Chinese medicine composition is compareed with original side Group compares, and index and spleen index, thymus index significantly reduce (P < 0.01) (table 6).Show that new Chinese medicine composition has the enhancing deficiency of vital energy The effect of the maincenter, periphery immune function of constitution mouse.
6 mouse spleen index of table, thymus index compare (n=8,)
Different letters indicate difference extremely significantly (P < 0.01).
Above-described embodiment is merely illustrative of the technical solution of the present invention, rather than is carried out to the design of the present invention and protection domain It limits, those of ordinary skill of the invention is modified or replaced equivalently technical scheme of the present invention, without departing from technology The objective and range of scheme, should all cover in scope of the presently claimed invention.

Claims (6)

1. the feedstock composition that a kind of health-care wine is made, which is characterized in that including former wine material and Chinese medicine composition;
The quality proportioning of the former wine material and the Chinese medicine composition is 10: 3;
The former wine material includes:Milled glutinous broomcorn millet and maize;
The Chinese medicine composition includes:Radix Astragali, Radix Codonopsis, Radix Glycyrrhizae, Chinese prickly ash and rhizoma zingiberis;
Wherein, the quality proportioning of milled glutinous broomcorn millet and maize is 4: 1;
Wherein, Chinese medicine composition includes according to the mass fraction:Radix Astragali 7.3-12.6, Radix Codonopsis 7.8-13.5, Radix Glycyrrhizae 4.8-7.2, flower Green pepper 0.5-4.4 and rhizoma zingiberis 2.7-5.6.
2. feedstock composition as described in claim 1, which is characterized in that according to the mass fraction, Chinese medicine composition includes following Raw material:
Radix Astragali 9, Radix Codonopsis 9, Radix Glycyrrhizae 6, Chinese prickly ash 2 and rhizoma zingiberis 4.
3. a kind of using the method for preparing health-care wine wine such as claim 1-2 any one of them feedstock compositions, feature exists In including the following steps:
S1, raw material is chosen:Choose milled glutinous broomcorn millet 75-85, maize 15-25, Radix Astragali 7.3-12.6, Radix Codonopsis 7.8-13.5, Radix Glycyrrhizae 4.8- 7.2, Chinese prickly ash 0.5-4.4 and rhizoma zingiberis 2.7-5.6;
S2, former wine is prepared:The milled glutinous broomcorn millet of selection and maize are made into obtain former wine using wine-making technology;
S3, encapsulation Chinese medicine:The Radix Astragali of selection, Radix Codonopsis, Radix Glycyrrhizae, Chinese prickly ash and rhizoma zingiberis are encapsulated into bag, Chinese herbal medicine bag is obtained;
S4, Chinese medicine is decocted:Then the Chinese herbal medicine bag of acquisition is placed in former wine, and former wine and Chinese herbal medicine bag is sealed in 80 DEG C -100 DEG C Under decoct 0.5h-1h, obtain health-care wine and make.
4. method as claimed in claim 3, which is characterized in that use wheat koji as the distiller's yeast for preparing former wine in step s 2.
5. method as claimed in claim 3, which is characterized in that after step s4, the health-care wine wine of acquisition is dispensed, And pasteurization is carried out, obtain final product.
6. a kind of made using the health-care wine as made from any one of claim 3-5 the methods.
CN201810573741.7A 2018-06-06 2018-06-06 A kind of feedstock composition that health-care wine is made, its health-care wine are made and preparation method thereof Pending CN108531338A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1226426A (en) * 1994-12-22 1999-08-25 山西大学 Hanjingbaoyuan beverage

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
CN1226426A (en) * 1994-12-22 1999-08-25 山西大学 Hanjingbaoyuan beverage

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Application publication date: 20180914