CN108524739A - A kind of gel agent for treating bedsore - Google Patents
A kind of gel agent for treating bedsore Download PDFInfo
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- CN108524739A CN108524739A CN201810667331.9A CN201810667331A CN108524739A CN 108524739 A CN108524739 A CN 108524739A CN 201810667331 A CN201810667331 A CN 201810667331A CN 108524739 A CN108524739 A CN 108524739A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/738—Rosa (rose)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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Abstract
The invention discloses a kind of gel agents for treating bedsore; it is characterized in that; long-acting bactericidal protective barrier can be formed in bed sore surface by treating the gel of bedsore; inhibit the invasion of bacterial fungus; generation that is fundamentally antipruritic and reducing bedsore; the invention efficiently solves that traditional medicament function and effect are poor, and the replacement cycle is short, needs the defect removed necrosis and promoted granulation.
Description
Technical field
The invention belongs to Field of Drug Discovery, are related to a kind of medicament of clinic treatment bedsore.
Background technology
Bedsore（Also known as pressure sore, pressure ulcer）, be cause for some reason ischemic cause local inflammatory response or even
Extraneous pathogen invasion generates local infection, and makes tissue necrosis.Bedsore is apt to occur in compression and lacks adipose tissue protection, no flesh
At the bone knuckle that pork pies are wrapped up in or muscle layer is relatively thin.Bedsore is still the first complication of patient bedridden in long term so far, tight due to occurring
Weight bedsore infects and dead patient ratio in bed crowd is caused to be up to 50%.According to related document report, there are about 60,000 people every year
Die of bedsore complication.It is No.1 " killer " that bedsore has become bed patient, should cause the enough attention of medical field.Bedsore is controlled
It treating, doctor removes necrosis and promote granulation and the doctor of profession is needed to go to operate based on removing necrosis and promoting granulation, costly, and pain is big, ineffective, because
This, the effective medicament for treating bedsore seems increasingly important for patients.
Currently, on the market bedsore paste treatment need remove necrotic tissue and promoting muscle growing, therapeutic effect unobvious, easily repeatedly the defects of.
The present invention proposes a kind of quick, long-acting treatment bedsore medicament.The gel that the present invention treats bedsore has long-acting bactericidal characteristic,
Antiseptic film can be formed in the surface of a wound of bedsore, the germ-free condition for keeping the surface of a wound lasting reduces intrusion of the bacterium to the surface of a wound, accelerates wound
The recovery in face.
Invention content
The purpose of the present invention is to solve the defects of existing band bed sore ointment, and a kind of organic nano HBP proposed is used as and kills
The band bed sore ointment of microbial inoculum.
To achieve the goals above, the present invention adopts the following technical scheme that：
A kind of a kind of gel agent for treating bedsore, which is characterized in that preparation method of gel agent that treating bedsore：
（1）Rilanit special and organic nano HBP are weighed according to certain mass ratio, and is thoroughly mixed uniformly, is obtained newborn
The organic nano HBP of change；
（2）Certain mass purified water is weighed, is added in carbomer, is stirred, add Sodium Hyaluronate, be sufficiently stirred
Uniformly；
（3）It weighs Seabuckthorn Oil, be added in the organic nano HBP being emulsified after Rosa Damascana is mixed evenly, carry out abundant
Stirring；
（4）By step（3）Product, be added to step（2）Product in, stir, then add triethanolamine thickening；
（5）Aloe liquid, glycerine and menthol are added to step（4）Product in, stir to get to treatment bedsore
Gel.
The technical advantage of the present invention：
Patent of the present invention not only solves the problems, such as that bedsore needs are removed necrosis and promoted granulation, while also efficiently solving general bedsore
Drug replacement cycle short problem.
Specific implementation mode
Embodiment 1
（1）Rilanit special 60.0g and organic nano HBP41.0g are weighed, and is thoroughly mixed uniformly, is emulsified
Organic nano HBP；
（2）Certain mass purified water 510.0g is weighed, 60.0g in carbomer is added, stirs, adds hyaluronic acid
Sodium 9.0g, stirs；
（3）Weigh Seabuckthorn Oil 1.5g, Rosa Damascana 15.0g is added to after being mixed evenly in the organic nano HBP being emulsified,
It is sufficiently stirred；
（4）By step（3）Product, be added to step（2）Product in, stir, then triethanolamine 2.0g is added to increase
It is thick；
（5）Aloe liquid 150.0g, glycerine 150.0g and menthol 1.5g are added to step（4）Product in, be sufficiently stirred
It is even to get to treatment bedsore gel.
Embodiment 2
（1）Rilanit special 60.0g and organic nano HBP41.0g are weighed, and is thoroughly mixed uniformly, is emulsified
Organic nano HBP；
（2）Certain mass purified water 515.0g is weighed, 60.0g in carbomer is added, stirs, adds hyaluronic acid
Sodium 4.0g, stirs；
（3）Weigh Seabuckthorn Oil 2.0g, Rosa Damascana 15.0g is added to after being mixed evenly in the organic nano HBP being emulsified,
It is sufficiently stirred；
（4）By step（3）Product, be added to step（2）Product in, stir, then triethanolamine 2.0g is added to increase
It is thick；
（5）Aloe liquid 150.0g, glycerine 150.0g and menthol 1.0g are added to step（4）Product in, be sufficiently stirred
It is even to get to treatment bedsore gel.
Embodiment 3
（1）Rilanit special 60.0g and organic nano HBP41.0g are weighed, and is thoroughly mixed uniformly, is emulsified
Organic nano HBP；
（2）Certain mass purified water 515.0g is weighed, 60.0g in carbomer is added, stirs, adds hyaluronic acid
Sodium 6.0g, stirs；
（3）Weigh Seabuckthorn Oil 1.0g, Rosa Damascana 15.0g is added to after being mixed evenly in the organic nano HBP being emulsified,
It is sufficiently stirred；
（4）By step（3）Product, be added to step（2）Product in, stir, then triethanolamine 1.0g is added to increase
It is thick；
（5）Aloe liquid 160.0g, glycerine 140.0g and menthol 1.0g are added to step（4）Product in, be sufficiently stirred
It is even to get to treatment bedsore gel.
The present invention is not limited to the above embodiments, other any to be made under without departing from essence of the present invention and principle
Modification, modification, simplified, combination etc., are considered equivalent displacement, are included in protection scope of the present invention.
Claims (2)
1. a kind of gel agent for treating bedsore, it is characterised in that：The medicament is by following component according to certain mass fraction set
At：Organic nano HBP 3.0~5.0, carbomer 4.0~6.0, rilanit special 5.0~8.0, purified water 40.0~55.0, three
Ethanol amine 0.1~0.2, Seabuckthorn Oil 0.1~0.2, Rosa Damascana 1.0~2.0, aloe liquid 10.0~20.0, menthol 0.1~
0.2, glycerine 10.0~15.0, Sodium Hyaluronate 0.3~1.0.
2. according to described in claim 1, which is characterized in that a kind of preparation method of gel that treating bedsore：
（1）Rilanit special and organic nano HBP are weighed according to certain mass ratio, and is thoroughly mixed uniformly, is obtained newborn
The organic nano HBP of change；
（2）Certain mass purified water is weighed, is added in carbomer, is stirred, add Sodium Hyaluronate, be sufficiently stirred
Uniformly；
（3）It weighs Seabuckthorn Oil, be added in the organic nano HBP being emulsified after Rosa Damascana is mixed evenly, carry out abundant
Stirring；
（4）By step（3）Product, be added to step（2）Product in, stir, then add triethanolamine thickening；
（5）Aloe liquid, glycerine and menthol are added to step（4）Product in, stir to get to treatment bedsore
Gel.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810667331.9A CN108524739A (en) | 2018-06-26 | 2018-06-26 | A kind of gel agent for treating bedsore |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810667331.9A CN108524739A (en) | 2018-06-26 | 2018-06-26 | A kind of gel agent for treating bedsore |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108524739A true CN108524739A (en) | 2018-09-14 |
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ID=63486995
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810667331.9A Pending CN108524739A (en) | 2018-06-26 | 2018-06-26 | A kind of gel agent for treating bedsore |
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| Country | Link |
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| CN (1) | CN108524739A (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101757075A (en) * | 2009-10-30 | 2010-06-30 | 吕晓梅 | Medicament of Chinese medicine for treating burn and bedsore and preparation method thereof |
| CN102100650A (en) * | 2011-01-28 | 2011-06-22 | 武汉耦合医学科技有限责任公司 | Gel medical supply for preventing bedsore and preparation method thereof |
| CN105055713A (en) * | 2015-09-16 | 2015-11-18 | 凌海市展望生物科技有限公司 | Drug composition for preventing or curing bedsore and preparation method thereof |
| CN106421392A (en) * | 2016-11-02 | 2017-02-22 | 福元药业股份有限公司 | Traditional Chinese medicinal gel for treating bedsore and preparation method of traditional Chinese medicinal gel |
| CN106619485A (en) * | 2015-11-02 | 2017-05-10 | 西安艾姆高分子材料有限公司 | Organic nanometer ointment for quickly restoring burn, scald and wound |
-
2018
- 2018-06-26 CN CN201810667331.9A patent/CN108524739A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101757075A (en) * | 2009-10-30 | 2010-06-30 | 吕晓梅 | Medicament of Chinese medicine for treating burn and bedsore and preparation method thereof |
| CN102100650A (en) * | 2011-01-28 | 2011-06-22 | 武汉耦合医学科技有限责任公司 | Gel medical supply for preventing bedsore and preparation method thereof |
| CN105055713A (en) * | 2015-09-16 | 2015-11-18 | 凌海市展望生物科技有限公司 | Drug composition for preventing or curing bedsore and preparation method thereof |
| CN106619485A (en) * | 2015-11-02 | 2017-05-10 | 西安艾姆高分子材料有限公司 | Organic nanometer ointment for quickly restoring burn, scald and wound |
| CN106421392A (en) * | 2016-11-02 | 2017-02-22 | 福元药业股份有限公司 | Traditional Chinese medicinal gel for treating bedsore and preparation method of traditional Chinese medicinal gel |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
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Application publication date: 20180914 |