CN108524710A - A kind of Chinese medicine composition and its preparation method and application for treating arthralgia - Google Patents

A kind of Chinese medicine composition and its preparation method and application for treating arthralgia Download PDF

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CN108524710A
CN108524710A CN201810596160.5A CN201810596160A CN108524710A CN 108524710 A CN108524710 A CN 108524710A CN 201810596160 A CN201810596160 A CN 201810596160A CN 108524710 A CN108524710 A CN 108524710A
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medicine composition
arthralgia
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孔祥军
杨铁成
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/889Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

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Abstract

The invention discloses a kind of Chinese medicine composition for treating arthralgia, the Chinese medicine composition is made of the raw material including following parts by weight:3 10 parts of pangolin, 3 10 parts of the rhizome of davallia, 3 10 parts of Sangzhi, base give birth to 25 parts, 24 parts of safflower, 0.02 0.04 parts of dragon's blood.Each reasonable raw material proportioning plays the effect of supplementing kidney qi, treatment of arthritis and promoting collateral and channels, wind-dispelling blood-nourishing, relaxing muscles and tendons nourishing the bone, invigorate blood circulation, removing blood stasis and analgesics jointly, to achieve the effect that treat arthrodynia.Meanwhile it is quick, it is at low cost, it is safe to use, it has no toxic side effect.The invention also discloses the preparation methods of above-mentioned Chinese medicine composition, and this method is simple to operation, can extract the active ingredient of each drug component to greatest extent, and the external preparation that can effectively treat arthralgia is made.

Description

A kind of Chinese medicine composition and its preparation method and application for treating arthralgia
Technical field
The present invention relates to technical field of traditional Chinese medicines, and in particular to a kind of Chinese medicine composition that treating arthralgia and its preparation side Method and application.
Background technology
Current life stress is increasing, for worker, the peasant of participation physical exertion, or even lacks doing for activity exercise Public room worker, because taking part in the work work for a long time, caused arthralgia of overworking, numb limb is extremely common. Arthralgia is mostly osteoproliferation, neurothlipsis or poor blood circulation caused by prolonged manual labor.
The drug of various treatment arthralgias exists in the prior art.However, treatment arthralgia in the prior art Drug, not only markedly slow, the course for the treatment of is long, spend high, final curative effect not it is obvious that and slowly effect, cannot timely reduction of patient Pain cannot effect a radical cure substantially, the long-term normal life for influencing patient.
Invention content
The purpose of the present invention is to provide a kind of Chinese medicine compositions for treating arthralgia, to solve existing treatment means Markedly slow, the problem of course for the treatment of is long, cost is high and cannot effect a radical cure.
To achieve the above object, the technical scheme is that:
A kind of Chinese medicine composition for treating arthralgia, the Chinese medicine composition is by including the raw material systems of following parts by weight At:3-10 parts of pangolin, 3-10 parts of the rhizome of davallia, Sangzhi 3-10 parts, base give birth to 2-5 parts, 2-4 parts of safflower, 0.02-0.04 parts of dragon's blood.
As a preferred solution, the Chinese medicine composition is made of the raw material including following parts by weight:Pangolin 5-8 parts, 5-8 parts of the rhizome of davallia, Sangzhi 5-8 parts, base give birth to 3-4 parts, 2-3 parts of safflower, 0.025-0.035 parts of dragon's blood.
As a preferred solution, the Chinese medicine composition is made of the raw material including following parts by weight:Pangolin 6.5 parts, 6.5 parts of the rhizome of davallia, 6.5 parts of Sangzhi, base give birth to 3.5 parts, 2.5 parts of safflower, 0.03 part of dragon's blood.
As a preferred solution, the Chinese medicine composition is external preparation.
Second object of the present invention is to provide a kind of preparation of the Chinese medicine composition for the treatment of arthralgia as described above Method, described method includes following steps:
Step 1:Weigh each raw material of corresponding parts by weight;
Step 2:Pangolin is fried using the copper pot of red copper;
Step 3:The pangolin fried and other each raw materials are placed in container, white wine, sealed soak 3 are added while hot A month or more, filter and remove residue obtained the Chinese medicine composition for the treatment of arthralgia.
As a preferred solution, the alcohol concentration of the white wine is 65% or more.
As a preferred solution, the total weight ratio of the white wine and each raw material is 25:1-15:1.
Third object of the present invention is to provide a kind of Chinese medicine compositions as described above to prepare treatment arthralgia Application in drug.
The main component pharmacology of the present invention is as follows:
Pangolin, it is salty, it is slightly cold.Return liver, stomach.Have effects that invigorate blood circulation, lower breast, detumescence and apocenosis.It is mainly used for controlling Treat the diseases such as arthralgia pain due to rheumatism, spasm of limbs, carbuncle swells, scrofula subcutaneous nodule.
The rhizome of davallia, bitter, temperature.Enter liver and kidney channel.Have effects that The strong bone of kidney tonifying, continues and hinders pain relieving.It is mainly used for treating kidney deficiency waist Bitterly, the diseases such as Hiccough and deaf, tooth mobility, falling winks frustrates, injured bone.
Sangzhi, slight bitter are mild-natured.Enter lung, kidney two warp.Have effects that wind-damp dispelling, degrading the channel, row aqueous vapor.It is mainly used for controlling Treat the diseases such as arthralgia pain due to rheumatism, apoplexy and hemiplegia, oedema tinea pedis, human body pruritus shoulder arm, joint pain numbness.
Safflower, it is acrid in flavour and warm in nature.Enter the heart, Liver Channel.Have effects that invigorate blood circulation, stasis eliminatings analgesic.It is mainly used for treating hemostasis work Bitterly, the diseases such as carbuncle swells, injury from falling down.
Dragon's blood, it is sweet, salty, it puts down.Converge to heart and liver channels.Have effects that invigorate blood circulation analgesic therapy, removing blood stasis and hemostasis, expelling pus and promoting granulation.For treating Traumatic injury, trusted subordinate's stasis caused pain, traumatic hemorrhage, sore such as do not hold back at the diseases.
The invention has the advantages that:
The drug for the treatment of arthralgia provided by the invention is using pangolin, the rhizome of davallia, Sangzhi, base life, safflower, dragon's blood medicine Material carries out rational proportion, plays supplement kidney qi, treatment of arthritis and promoting collateral and channels, wind-dispelling blood-nourishing, relaxing muscles and tendons nourishing the bone, invigorate blood circulation, removing blood stasis and analgesics jointly The effect of, to achieve the effect that treat arthrodynia.Meanwhile it is quick, it is at low cost, it is safe to use, it has no toxic side effect.
Preparation method of the present invention is simple, can extract the active ingredient of each drug component to greatest extent, and being made can The effectively external preparation for the treatment of arthralgia.
Specific implementation mode
The following examples are used to illustrate the present invention, but are not intended to limit the scope of the present invention..
Embodiment 1
The present embodiment provides a kind of Chinese medicine composition for treating arthralgia, the Chinese medicine composition is by including following weight The raw material of grams is made:6.5 grams of pangolin, 6.5 grams of the rhizome of davallia, 6.5 grams of Sangzhi, 3.5 grams of base life, 2.5 grams of safflower, dragon's blood 0.03 Gram.
The Chinese medicine composition is external preparation.
The preparation method of above-mentioned Chinese medicine composition includes the following steps:
Step 1:Weigh each raw material of corresponding weight grams;
Step 2:Pangolin is fried using the copper pot of red copper;
Step 3:The pangolin fried and other each raw materials are placed in container, white wine, sealed soak 3 months is added More than, filter and remove residue obtains the Chinese medicine composition for the treatment of arthralgia.
The alcohol concentration of the white wine is 80%.
The total weight ratio of the white wine and each raw material is 20:1.
Embodiment 2
The present embodiment provides a kind of Chinese medicine composition for treating arthralgia, the Chinese medicine composition is by including following weight The raw material of grams is made:3 grams of pangolin, 10 grams of the rhizome of davallia, 3 grams of Sangzhi, 5 grams of base life, 2 grams of safflower, 0.04 gram of dragon's blood.
The Chinese medicine composition is external preparation.
The preparation method of above-mentioned Chinese medicine composition includes the following steps:
Step 1:Weigh each raw material of corresponding weight grams;
Step 2:Pangolin is fried using the copper pot of red copper;
Step 3:The pangolin fried and other each raw materials are placed in container, white wine, sealed soak 3 months is added More than, filter and remove residue obtains the Chinese medicine composition for the treatment of arthralgia.
The alcohol concentration of the white wine is 65%.
The total weight ratio of the white wine and each raw material is 25:1.
Embodiment 3
The present embodiment provides a kind of Chinese medicine composition for treating arthralgia, the Chinese medicine composition is by including following weight The raw material of grams is made:10 grams of pangolin, 3 grams of the rhizome of davallia, 10 grams of Sangzhi, 2 grams of base life, 4 grams of safflower, 0.02 gram of dragon's blood.
The Chinese medicine composition is external preparation.
The preparation method of above-mentioned Chinese medicine composition includes the following steps:
Step 1:Weigh each raw material of corresponding weight grams;
Step 2:Pangolin is fried using the copper pot of red copper;
Step 3:The pangolin fried and other each raw materials are placed in container, white wine, sealed soak 3 months is added More than, filter and remove residue obtains the Chinese medicine composition for the treatment of arthralgia.
The alcohol concentration of the white wine is 70%.
The total weight ratio of the white wine and each raw material is 15:1.
Embodiment 4
The present embodiment provides a kind of Chinese medicine composition for treating arthralgia, the Chinese medicine composition is by including following weight The raw material of grams is made:5 grams of pangolin, 8 grams of the rhizome of davallia, 5 grams of Sangzhi, 4 grams of base life, 2 grams of safflower, 0.035 gram of dragon's blood.
The Chinese medicine composition is external preparation.
The preparation method of above-mentioned Chinese medicine composition includes the following steps:
Step 1:Weigh each raw material of corresponding weight grams;
Step 2:Pangolin is fried using the copper pot of red copper;
Step 3:The pangolin fried and other each raw materials are placed in container, white wine, sealed soak 3 months is added More than, filter and remove residue obtains the Chinese medicine composition for the treatment of arthralgia.
The alcohol concentration of the white wine is 90%.
The total weight ratio of the white wine and each raw material is 25:1.
Embodiment 5
The present embodiment provides a kind of Chinese medicine composition for treating arthralgia, the Chinese medicine composition is by including following weight The raw material of grams is made:8 grams of pangolin, 5 grams of the rhizome of davallia, 8 grams of Sangzhi, 3 grams of base life, 3 grams of safflower, 0.025 gram of dragon's blood.
The Chinese medicine composition is external preparation.
The preparation method of above-mentioned Chinese medicine composition includes the following steps:
Step 1:Weigh each raw material of corresponding weight grams;
Step 2:Pangolin is fried using the copper pot of red copper;
Step 3:The pangolin fried and other each raw materials are placed in container, white wine, sealed soak 3 months is added More than, filter and remove residue obtains the Chinese medicine composition for the treatment of arthralgia.
The alcohol concentration of the white wine is 100%.
The total weight ratio of the white wine and each raw material is 15:1.
The present invention chooses 200 arthralgia patient medical records, using Chinese medicine composition provided by the invention to above-mentioned patient It is treated, other drugs, the foods such as no smoking and drinking, capsicum, mung bean is cut out during treatment, while avoiding other extraneous factors Influence.
Curative effect determinate standard:
It cures:After treatment, symptoms of joint pain disappears, no recurrence;
Effectively:After treatment, symptoms of joint pain mitigates;
In vain:After treatment, symptoms of joint pain is unchanged.
After treatment after a period of time, observation patient profiles, invalid 4%, effective 39%, cure 57%, i.e., it is of the invention The drug effective percentage of the treatment pain of offer is 96%.As it can be seen that Chinese medicine composition provided by the invention is to arthrodynia patient There is particularly preferred effect.
Typical case in above-mentioned 200 patients is as follows:
Effect example 1:
Mr. Wang, man, 61 years old, leg joint pain 10 years, Mr. Wang attempted many therapies for the treatment of, but final Leg joint pain could not be cured.Medicinal liquor made of the Chinese medicine composition of the offer of the embodiment of the present invention 1 is provided in July, 2016, Outer wiping is carried out to the leg joint position of pain, is wiped 3-5 times daily.Leg section pain symptom is closed after 10 days to mitigate, after 4 months, pain Symptom disappears, and does not recur so far.
Effect example 2:
Mrs Bai, female, 57 years old, swivel of hand pain 3 years, Mrs's Bai Chinese medicine doctor trained in Western medicine was all treated, also could not be complete but final It is complete to cure, medicinal liquor made of the Chinese medicine composition of the offer of the embodiment of the present invention 2 is provided in December, 2015, the hand of pain is closed It saves position and carries out outer wiping, wipe 3-5 times daily.Defensive position symptoms of joint pain mitigates within 4 days, and after 1 month, swivel of hand pain symptom disappears It loses, did not recurred so far.
Effect example 3:
Mr. Wang, man, 59 years old, shoulder arthralgia 6 years.The Chinese medicine for beginning to use the embodiment of the present invention 4 to provide for 2 months 2016 Medicinal liquor made of composition carries out outer wiping to the shoulder joint position of pain, wipes 3-5 times daily.Back porch symptoms of joint pain subtracts within 6 days Gently, after 2 months, shoulder arthralgia symptom disappears, and does not recur so far.
Effect example 4:
Mrs Wu, female, 56 years old, hip arthralgia 4 years.The Chinese medicine for beginning to use in May, 2015 embodiment of the present invention 5 to provide Medicinal liquor made of composition carries out outer wiping to the hip joint part of pain, wipes 3-5 times daily.Hip symptoms of joint pain subtracts after 7 days Gently, after 3 months, hip symptoms of joint pain disappears, and does not recur so far.
Although above having used general explanation and specific embodiment, the present invention is described in detail, at this On the basis of invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Therefore, These modifications or improvements without departing from theon the basis of the spirit of the present invention belong to the scope of protection of present invention.

Claims (8)

1. a kind of Chinese medicine composition for treating arthralgia, which is characterized in that the Chinese medicine composition is by including following parts by weight Several raw materials are made:3-10 parts of pangolin, 3-10 parts of the rhizome of davallia, Sangzhi 3-10 parts, base give birth to 2-5 parts, 2-4 parts of safflower, dragon's blood 0.02-0.04 parts.
2. it is according to claim 1 treatment arthralgia Chinese medicine composition, which is characterized in that the Chinese medicine composition by Raw material including following parts by weight is made:5-8 parts of pangolin, 5-8 parts of the rhizome of davallia, Sangzhi 5-8 parts, base life 3-4 parts, safflower 2- 3 parts, 0.025-0.035 parts of dragon's blood.
3. it is according to claim 1 treatment arthralgia Chinese medicine composition, which is characterized in that the Chinese medicine composition by Raw material including following parts by weight is made:6.5 parts of pangolin, 6.5 parts of the rhizome of davallia, 6.5 parts of Sangzhi, base give birth to 3.5 parts, safflower 2.5 parts, 0.03 part of dragon's blood.
4. the Chinese medicine composition for the treatment of arthralgia according to claim 1, which is characterized in that the Chinese medicine composition is External preparation.
5. a kind of preparation method of the Chinese medicine composition for the treatment of arthralgia according to any one of claims 1-4, feature It is, described method includes following steps:
Step 1:Weigh each raw material of corresponding parts by weight;
Step 2:Pangolin is fried using the copper pot of red copper;
Step 3:The pangolin fried and other each raw materials are placed in container, white wine, sealed soak 3 months or more is added, Filter and remove residue obtains the Chinese medicine composition for the treatment of arthralgia.
6. the preparation method of the Chinese medicine composition for the treatment of arthralgia according to claim 5, which is characterized in that described white The alcohol concentration of wine is 65% or more.
7. the preparation method of the Chinese medicine composition for the treatment of arthralgia according to claim 5, which is characterized in that described white The total weight ratio of wine and each raw material is 25:1-15:1.
8. a kind of Chinese medicine composition according to any one of claims 1-4 answering in the drug for preparing treatment arthralgia With.
CN201810596160.5A 2018-06-11 2018-06-11 A kind of Chinese medicine composition and its preparation method and application for treating arthralgia Pending CN108524710A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1181254A (en) * 1996-11-01 1998-05-13 戴光臻 Rheumatism paste and its preparing method
CN1806837A (en) * 2005-01-21 2006-07-26 杨彩芹 Hyperosteogeny-treating ointment
CN101757148A (en) * 2008-12-24 2010-06-30 天津市中宝制药有限公司 Traditional Chinese medicine composition for treating cervical spondylosis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1181254A (en) * 1996-11-01 1998-05-13 戴光臻 Rheumatism paste and its preparing method
CN1806837A (en) * 2005-01-21 2006-07-26 杨彩芹 Hyperosteogeny-treating ointment
CN101757148A (en) * 2008-12-24 2010-06-30 天津市中宝制药有限公司 Traditional Chinese medicine composition for treating cervical spondylosis

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
苗明三 等: "《中药大辞典》", 30 June 2017, 山西科学技术出版社 *
韩树勤: "《调理药酒》", 31 July 2012, 农村读物出版社 *

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