CN108524556A - A kind of Chinese medicine composition and the preparation method and application thereof - Google Patents
A kind of Chinese medicine composition and the preparation method and application thereof Download PDFInfo
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- CN108524556A CN108524556A CN201810649759.0A CN201810649759A CN108524556A CN 108524556 A CN108524556 A CN 108524556A CN 201810649759 A CN201810649759 A CN 201810649759A CN 108524556 A CN108524556 A CN 108524556A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
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Abstract
The invention discloses a kind of Chinese medicine composition and the preparation method and application thereof, which is made by the raw material of following parts by weight:1 10 parts of the shell of tamarind kernel, 15 parts of tamarind flower, preparation method are the shell for the tamarind kernel for taking corresponding weight proportion, tamarind flower, are crushed after drying, be added appropriate amount of purified water, stirring, boil 3 10 minutes to get.The Chinese medicine composition of the present invention has clearing heat and detoxicating, strengthening vital QI to eliminate pathogenic factors, promoting blood circulation and removing blood stasis, swelling and pain relieving, expelling pus and promoting granulation, the effect of putrefaction-removing granulation-promoting.Clinically Chinese medicine composition of the invention can be used for the treatment of fungal infection disease, and curative for effect, side effect is slight.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine, it particularly relates to a kind of Chinese medicine composition and preparation method thereof
With application.
Background technology
Fungal infection can be divided into two class of the shallow fungal infection of table and deep fungal infection, and the shallow infection of table is to invade skin by tinea bacterium
Caused by the body surfaces such as skin, hair, nail, incidence is high, and harmfulness is smaller.Deep fungal infection is by candida albicans and hidden ball
Caused by bacterium invades internal organs and deep tissue, incidence is low, and harmfulness is big.
There are many medicament categories currently used for treating fungal infection, but most weak curative effect, and the course for the treatment of is longer, and side effect is more
Easily recurrence, cannot eradicate.
Invention content
For above-mentioned technical problem in the related technology, the present invention proposes a kind of Chinese medicine composition and preparation method thereof and answers
With the above-mentioned deficiency of the prior art can be overcome.
To realize the above-mentioned technical purpose, the technical proposal of the invention is realized in this way:
A kind of Chinese medicine composition is made by the raw material of following parts by weight:The shell of tamarind kernel(That is outer kind of the black of tamarind
Skin)1-10 parts, 1-5 parts of tamarind flower.
Preferably, the Chinese medicine composition is made by the raw material of following parts by weight:3-8 parts of the shell of tamarind kernel, sieve
Shake sub- flower 1-3 parts.
Preferably, the Chinese medicine composition is made by the raw material of following parts by weight:5 parts of the shell of tamarind kernel, sieve shake
1 part of sub- flower.
Tamarind is Sterculiaceae plant sterculia nobilis(Scientific name:Sterculia nobilis Smith)Seed.With disappearing with stomach
The effect of food, removing toxic substances desinsection.Food, abdominal pain due to enterositosis, colic, the rotten head ulcer of children are spat for regurgitation.
According to another aspect of the present invention, the preparation method for providing above-mentioned Chinese medicine composition, the specific steps are:It takes corresponding
Shell, the tamarind flower of the tamarind kernel of weight proportion, crush after drying, and appropriate amount of purified water is added, and 3-10 is boiled in stirring
Minute to get.
Preferably, the preparation method of above-mentioned Chinese medicine composition is:Take shell, the sieve of the tamarind kernel of corresponding weight proportion
Shake sub- flower, crushed after drying, be added appropriate amount of purified water, stirring, boil 5 minutes to get.
The invention also discloses application of the above-mentioned Chinese medicine composition in the drug for the treatment of fungal infectious disease.
When specifically used, suitable Drug level and administrated method, tamarind are selected according to the degree of infection site, infection
The shell of kernel, the Drug level that the total concentration of tamarind flower is 1.5-5wt% are appropriate, and administrated method includes soak and outer
It applies.
Beneficial effects of the present invention:The Chinese medicine composition of the present invention has clearing heat and detoxicating, strengthening vital QI to eliminate pathogenic factors, promoting blood circulation and removing blood stasis, disappear
Swollen analgesic, expelling pus and promoting granulation, the effect of putrefaction-removing granulation-promoting, the various cells of energy interactive adjustment and Porcine HGF and extracellular matrix,
Improve microcirculation, adjust autoimmunity and innervation function, promote the growth of fibroblast, epithelial cell, activates chemotactic
Macrophage enhances its phagocytosis, adjusts acid-base value, improves the permeability of capillary.Clinically Chinese medicine group of the invention
The treatment that object can be used for fungal infection disease is closed, short treating period is curative for effect, and side effect is slight.
Specific implementation mode
The technical scheme in the embodiments of the invention will be clearly and completely described below, it is clear that described implementation
Example is only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, this field is common
The every other embodiment that technical staff is obtained, shall fall within the protection scope of the present invention.
Embodiment 1
Shell, the 50g tamarind flowers for taking 10g tamarind kernels, crush after drying, and 1200mL pure water is added, and stirring is boiled
3 minutes to get Chinese medicine composition.
Embodiment 2
Shell, the 10g tamarind flowers for taking 100g tamarind kernels, crush after drying, and 2100mL pure water is added, and stirring is boiled
10 minutes are boiled to get Chinese medicine composition.
Embodiment 3
Shell, the 10g tamarind flowers for taking 50g tamarind kernels, crush after drying, and 1450mL pure water is added, and stirring is boiled
5 minutes to get Chinese medicine composition.
Embodiment 4
Shell, the 10g tamarind flowers for taking 30g tamarind kernels, crush after drying, and 1950mL pure water is added, and stirring is boiled
5 minutes to get Chinese medicine composition.
Embodiment 5
Shell, the 30g tamarind flowers for taking 80g tamarind kernels, crush after drying, and 2100mL pure water is added, and stirring is boiled
5 minutes to get Chinese medicine composition.
Experimental example 1
Chinese medicine composition prepared by embodiment 2 is dropped on the fungus colony for growing vigorous black, drop medicine is primary daily, drips medicine three
Fungus colony variation is observed after it, visual results are shown:Ashy green color or grey is presented in fungus colony color change.Explanation
The Chinese medicine has special effect to fungi.
Experimental example 2
The case 50 of ear, hand, leg or trunk fungal infection is collected, wherein man 22, female 28, age 5-55 Sui,
Average age 30 years old;Chinese medicine composition prepared by embodiment 4 is applied to these cases, and administrated method is outer painting fungal infection portion
Position applies 1 time for every eight hours, and result is observed after applying 3 times, 3 days daily.
The result shows that:50 patients, 45 patient affected part drying incrustations are cured, and cure rate reaches 90%, 3 patient affected parts
It has clear improvement, there is certain improvement in 2 patient affected parts.
Experimental example 3
Chinese medicine composition prepared by embodiment 4 is applied to the case of forehead fungal infection swelling, and administrated method is soak forehead
Affected part, each soak 2 hours, daily soak 4 times, observation is as a result, affected part swelling is obviously subsided after 6 hours 1 time, 1 day.
Experimental example 4
Chinese medicine composition prepared by embodiment 3 is applied to the case with buttocks fungal infection running sore, and administrated method is each
Soak 3 hours, soak 1 time for every eight hours, daily soak 3 times, after soak 1 day, the running sore for observing swelling flattens, and obviously disappears
It is swollen.
Experimental example 5
Shell, the 10g tamarind flowers for taking 50g tamarind kernels, crush after drying, and 1950mL pure water is added, and stirring is boiled
5 minutes, with the program of aseptic technique, sterile Chinese medicine is prepared, the case of the nasosinusitis for fungal infection, administrated method
For:By the collunarium method collunarium of science, first 2 days daily collunariums 4 times drip 1 time for every 6 hours, and latter 3 days daily collunariums 3 times, every 8 is small
When drop 1 time, 5 days after observe as a result, nasal obstruction, sneezing, stream clear yellow viscous nasal mucus symptom gradually eliminate, smelly feel function is gradually extensive
It is multiple.
Treatment, purely with this traditional Chinese medicine composition for treating, is not controlled using other drug cooperations with the whole process of above-mentioned case
It treats.
The above-mentioned experiment of comprehensive analysis and case application study, illustrate that this Chinese medicine composition is sensitive to fungi, can effectively control
Treat fungal infectious disease.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention
With within principle, any modification, equivalent replacement, improvement and so on should all be included in the protection scope of the present invention god.
Claims (6)
1. a kind of Chinese medicine composition, which is characterized in that be made by the raw material of following parts by weight:The shell 1-10 of tamarind kernel
Part, 1-5 parts of tamarind flower.
2. Chinese medicine composition according to claim 1, which is characterized in that be made by the raw material of following parts by weight:Tamarind fruit
3-8 parts of the shell of benevolence, 1-3 parts of tamarind flower.
3. Chinese medicine composition according to claim 1, which is characterized in that be made by the raw material of following parts by weight:Tamarind fruit
5 parts of the shell of benevolence, 1 part of tamarind flower.
4. according to the preparation method of claim 1-3 any one of them Chinese medicine compositions, which is characterized in that corresponding weight is taken to match
Shell, the tamarind flower of the tamarind kernel of ratio, crush after drying, and appropriate amount of purified water is added, and stirring is boiled 3-10 minutes,
To obtain the final product.
5. the preparation method of Chinese medicine composition according to claim 4, which is characterized in that sieve of corresponding weight proportion is taken to shake
Shell, the tamarind flower of sub- kernel, crush after drying, be added appropriate amount of purified water, stirring, boil 5 minutes to get.
6. application of the Chinese medicine composition in the drug for the treatment of fungal infectious disease according to claim 1-3.
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Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104814944A (en) * | 2015-05-07 | 2015-08-05 | 黑龙江中医药大学 | Transdermal patch for preventing and treating lumbar disc herniation and preparation method thereof |
CN105521380A (en) * | 2014-11-27 | 2016-04-27 | 李冉 | Traditional Chinese medicine for treating tinea cruris |
CN106614798A (en) * | 2016-12-22 | 2017-05-10 | 重庆医学检验试剂研究所 | Composition, application in microorganism removal thereof and disinfecting fluid |
-
2018
- 2018-06-22 CN CN201810649759.0A patent/CN108524556B/en active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105521380A (en) * | 2014-11-27 | 2016-04-27 | 李冉 | Traditional Chinese medicine for treating tinea cruris |
CN104814944A (en) * | 2015-05-07 | 2015-08-05 | 黑龙江中医药大学 | Transdermal patch for preventing and treating lumbar disc herniation and preparation method thereof |
CN106614798A (en) * | 2016-12-22 | 2017-05-10 | 重庆医学检验试剂研究所 | Composition, application in microorganism removal thereof and disinfecting fluid |
Non-Patent Citations (3)
Title |
---|
ZHANG JIAO-JIAO,等: "Green Extraction of Natural Antioxidants from the Sterculia nobilis Fruit Waste and Analysis of Phenolic Profile", 《MOLECULES》 * |
任惠等: "苹婆种子营养及抗氧化活性 ", 《植物科学学报》 * |
南京中医药大学编著: "《中药大辞典》", 30 June 2014, 上海科学技术出版社 * |
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