CN108477614A - Blackberry, blueberry composition and preparation method thereof for improving sleep quality - Google Patents
Blackberry, blueberry composition and preparation method thereof for improving sleep quality Download PDFInfo
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Life Sciences & Earth Sciences (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Botany (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
This application provides a kind of blackberry, blueberry compositions for improving sleep quality.The blackberry, blueberry composition includes the raw material components of following parts by weight：45~90 parts of blackberry extract, 13~35 parts of Semen Phaseoli extract, 7~19 parts of Semen Nelumbinis extract, 1~5 part of Bulbus Lilii extract, 15 parts of Semen Sesami Nigrum extract, 2~5 parts of Arillus Longan extract, 1~3 part of termite extract and 37 parts of Fructus Jujubae extract.The content of present invention, which complies with the heart quiet god that clears away heart-fire, to eliminate disease and prolong life, the characteristics of improving sleep, prescription is carried out by the objective of nourishing blood and tranquilization, suitable and daily consumption, and it is in good taste, the present invention, by adding compound without side-effects, significantly increases the effect of it improves sleep quality on the basis of effect is slept in the original improvement of blackberry, blueberry.The effect of being easy to receive for crowd, certain improvement sleep quality can be reached.
Description
Technical field
The invention belongs to food processing technology fields, in particular to a kind of blackberry, blueberry group for improving sleep quality
Close object and preparation method thereof.
Background technology
The work of fast pace high intensity, the competition taxed one's ingenuity, undying pressure, long-term stress etc. are all existing
The heavy burden that generation social people bear.In addition people in middle age physiological function turns to decline by containing, there is physical function decline in many people,
Metal fatigue, the sleep symptom for belonging to the loss of Chinese medicine heart arteries and veins such as bad even more form invisible stress, quality of life by
To seriously affecting.
Currently, the treatment to poor sleeping quality, Western medicine mostly uses hypnotic sedative agent, and effect is preferable, but long-term use has one
Fixed drug resistance and dependence, and larger side effect can be brought to human body.Although also have improves in sleep quality at present
Medicine, but be that effect is not notable, the course for the treatment of is long, treatment is not thorough, easily recurs the shortcomings that generally existing.Chinese medicine common medicine has tranquilizing cinnabar
Ball, tianwangbuxin pills etc., but the applicable surface of these medicines is relatively narrow, and effect is not too ideal.
On the basis of the dietary therapy of Chinese medicine (integration of drinking and medicinal herbs) health, more and more dieticians close the food materials of integration of drinking and medicinal herbs
Reason collocation achievees the purpose that improve sleep quality by the effect of four property five tastes channel tropisms of food materials.
Blackberry, blueberry contains Polyphenols, flavonoids active material, rich in anthocyanidin, procyanidine, SOD, ellagic acid, Ellagitannins
Acid, salicylic acid, contain 20 kinds of amino acid, and total content is up to 1000mg/100g, contains multivitamin, vitamin E
Content is 6-7 times of apple, 4 times of citrus；Ascorbic content is 6 times of grape, 50 times of apple；Organic acid 1.2-
1.9%.Trace selenium content 1.0-2.7lug/g, content occupy first of fruit.Science certification, these groups contained by blackberry, blueberry
Point be natural super anti-oxidation active substance, oxidation resistance be 4 times of other fruit, 10 times of vegetables, 40 times of cereal.It is black
The certain kind of berries is known as " fruit of life ", and blackberry, blueberry is not only a kind of delicate fruit, and in terms of medicine, cosmetics, health food processing
It is rare delicacy excellent product that extensive purposes, which is fresh,；Blackberry fruit is not only suitable fresh food, can also be processed into fruit juice, preserved fruit, fruit
Sauce etc. or rare natural pigment and medical material.Therefore, blackberry, blueberry is that have higher economic value and wide developmental research
One of small bavin fruit fruit tree of novel economizer type of foreground.
The study found that often feeding blackberry fruit can achieve the purpose that certain improvement sleep quality, if it is possible to fully profit
With this characteristic of blackberry, blueberry, certain compatibility combination is carried out in conjunction with the thought of the long integration of drinking and medicinal herbs of motherland, developing can fill
The blank spot for dividing the consumable products for improving sleep quality that will fill up industry.
Invention content
The main purpose of the present invention is to provide a kind of health preserving health-care foods, for improving sleep quality.
To achieve the goals above, according to an aspect of the invention, there is provided it is a kind of for improving the black of sleep quality
Certain kind of berries composition.
The blackberry, blueberry composition includes the raw material components of following parts by weight：45~90 parts of blackberry extract, 13~35 parts
Semen Phaseoli extract, 7~19 parts of Semen Nelumbinis extract, 1~5 part of Bulbus Lilii extract, 1-5 parts of Semen Sesami Nigrum extract, 2
~5 parts of Arillus Longan extract, 1~3 part of termite extract and 3-7 parts of Fructus Jujubae extract.
Further, the blackberry, blueberry composition for improving sleep quality includes the raw material components of following portions by weight：55~
70 parts of blackberry extract, 20~30 parts of Semen Phaseoli extract, 10~16 parts of Semen Nelumbinis extract, the extraction of 2~4 parts of lily
Object, 2-4 parts of Semen Sesami Nigrum extract, 2~4 parts of Arillus Longan extract, 1~3 part of termite extract and 4-6 parts of jujube
Extract.
Further, the blackberry, blueberry composition for improving sleep quality includes the raw material components of following portions by weight：60 parts
Blackberry extract, 25 parts of Semen Phaseoli extract, 13 parts of Semen Nelumbinis extract, 3 parts of Bulbus Lilii extract, 3 parts of Semen sesami nigrum
Extract, 3 parts of Arillus Longan extract, 2 parts of termite extract and 5 parts of Fructus Jujubae extract.
Further, the blackberry, blueberry composition for improving sleep quality further includes 1~3 part of Chinese medical extract, in described
Medicament extract includes the raw material components of following parts by weight：10~30 parts of mulberries, 5~15 parts of mulberry leaf, 15~20 parts of chrysanthemum
Flower, 14~23 parts of matrimony vine, 13~25 parts of Schisandra chinensis and 1~6 part of donkey-hide gelatin.
The further product form for improving the blackberry, blueberry composition of sleep quality is concentrate, fruit juice, jam, capsule
Agent, tablet or dry powder.
To achieve the goals above, according to another aspect of the present invention, it also additionally provides above-mentioned for improving sleep matter
The processing method of the blackberry, blueberry composition of amount.
Processing method according to the present invention for improving the blackberry, blueberry composition of sleep quality, this method include as follows successively
Step：
Step 1, the preparation of blackberry extract：The blackberry, blueberry cleaned up is placed in refiner, addition weight is blackberry, blueberry 5-8
Times ethanol solution, homogenate extraction, obtain filtrate, will filtrate carry out ultrasonic extraction after centrifuge, collect centrifugate, to centrifugate into
Row distillation collects the fraction at 45~55 DEG C to get blackberry extract；
Step 2, the preparation of termite extract：It captures wild termite and carries out cleaning and sterilizing, impregnated with acetone solution, centrifuged
Go out acetone leaching liquor, carrying out recycling drying to acetone leaching liquor obtains termite extract.
Step 3：By blackberry extract, Semen Phaseoli extract, Semen Nelumbinis extract, Bulbus Lilii extract, Semen Sesami Nigrum extract, dragon
Eye meat extract, termite extract and Fructus Jujubae extract are spare after being weighed according to each plant demand；
Step 4, all raw materials in step 3 are uniformly mixed, according to common process be added customary adjuvant be made concentrate,
Fruit juice, pulp, dry powder, capsule or tablet.
Further, distillation pressure is 170MPa in step 1,
Further, the temperature of ultrasonic extraction is 35~40 DEG C, ultrasonic power 150W in step 1, ultrasonic extraction
Time is 50~80min.
Further, in the blending process of the step 3, it is also added with 1~3 part of Chinese medical extract, the Chinese medicine carries
It includes the raw material components of following parts by weight to take object：10~30 parts of mulberries, 5~15 parts of mulberry leaf, 15~20 parts of chrysanthemum, 14
~23 parts of matrimony vine, 13~25 parts of Schisandra chinensis and 1~6 part of donkey-hide gelatin.
Further, the Chinese medical extract is prepared via a method which：
Medicinal powder is made through drying, crushing in each raw material, the ethanol solution for being 40~65% with percent by volume is to the medicine
Then powder ultrasonic extraction, centrifugation, concentration are dried in vacuum drying chamber, temperature parameter is 75 DEG C~80 DEG C, and vacuum degree is negative
Between pressing 0.08Mpa and negative pressure 0.1Mpa, Chinese medical extract is obtained.
Semen Phaseoli extract, Semen Nelumbinis extract, Bulbus Lilii extract, Semen Sesami Nigrum extract, arillus longan extraction in the present invention
Object and Fructus Jujubae extract are commercial product,
Semen Phaseoli extract：Medicines and Health Product, beverage/food additive.It is mild-natured；It is sweet in flavor, sour；The thoughts of returning home, small intestinl channel.Li Shui
Detumescence, removing toxic substances apocenosis.For oedema turgor, tinea pedis limb is swollen, and yellow subcutaneous ulcer urinates red, beriberoid pyretic arthralgia, carbuncle sore tumefacting virus, abdominalgia with intestinal abscess.
Semen Nelumbinis extract：Medicines and Health Product, beverage/food additive.It is mild-natured；It is sweet in flavor, puckery；Returns spleen, kidney, the heart channel of Hang-Shaoyin.Tonifying spleen stops
It rushes down, the puckery essence of kidney-nourishing, mental-tranquilization.For spleen deficiency chronic diarrhea, seminal emission is under, palpitation and insomnia.
Bulbus Lilii extract：Fine brownish-yellow powder.It is cold in nature；It is sweet in flavor；Distributed in heart and lung channels.Yin nourishing and lung moistening, clearing away the heart fire and tranquillizing.For
Yin chronic cough, blood-stained sputum, dysphoria palpitates with fear, insomnia and dreamful sleep are absent-minded.
Semen Sesami Nigrum extract：Medicines and Health Product, beverage/food additive.It is mild-natured；It is sweet in flavor；Return liver, kidney, large intestine channel.Tonifying liver
Kidney, benefiting essence-blood moisturize intestines.For dizzy, Hiccough and deaf, poliosis, post disease alopecia, dry constipation of intestines.
Arillus Longan extract：Brownish-yellow powder.Medicines and Health Product, beverage/food additive.It is warm-natured；It is sweet in flavor；The thoughts of returning home, spleen
Through.Tonifying heart and spleen, nourishing blood and tranquilization.For insufficiency of vital energy and blood, palpitaition is seized with terror secondary, forgetful insomnia, blood deficiency chlorosis.
Fructus Jujubae extract：Medicines and Health Product, drink and food additive.It is warm-natured；It is sweet in flavor；Returns spleen, stomach.Tonifying middle-Jiao and Qi,
Nourishing blood and tranquilization.For spleen eating less, weak loose stool, married woman is dirty dry.
The content of present invention, which complies with the heart quiet god that clears away heart-fire, to eliminate disease and prolong life, the characteristics of improving sleep, pass through nourishing blood and tranquilization
Objective carries out prescription, is suitble to and daily consumption, and in good taste, the present invention on the basis of blackberry, blueberry original improvements sleep effect,
By adding compound without side-effects, the effect of it improves sleep quality is significantly increased.It is easy to receive for crowd, one can be reached
The effect of fixed improvement sleep quality.
Specific implementation mode
It is right below in conjunction with the embodiment of the present application in order to make those skilled in the art more fully understand application scheme
Technical solution in the embodiment of the present application is clearly and completely described, it is clear that described embodiment is only the application one
Partial embodiment, instead of all the embodiments.Based on the embodiment in the application, those of ordinary skill in the art are not having
The every other embodiment obtained under the premise of creative work is made, shall fall within the protection scope of the present application.
In addition, term " comprising " and his any deformation, it is intended that cover it is non-exclusive include, for example, containing
A series of product of raw materials or the method for series of steps those of are not necessarily limited to clearly to list raw material or step, but can wrap
It includes not listing clearly or for the intrinsic other steps of these methods, product or raw material.
It should be noted that in the absence of conflict, the features in the embodiments and the embodiments of the present application can phase
Mutually combination.
One aspect of the present invention provides a kind of blackberry, blueberry composition for improving sleep quality, including following parts by weight
Several raw material components：45~90 parts of blackberry extract, 13~35 parts of Semen Phaseoli extract, the extraction of 7~19 parts of lotus seeds
Object, 1~5 part of Bulbus Lilii extract, 1-5 parts of Semen Sesami Nigrum extract, 2~5 parts of Arillus Longan extract, 1~3 part of termite carry
Take object and 3-7 parts of Fructus Jujubae extract.
On the basis of the above embodiment, the alimentation composition of nourishing heart further includes 1~3 part of Chinese medical extract, described
Chinese medical extract includes the raw material components of following parts by weight：10~30 parts of mulberries, 5~15 parts of mulberry leaf, 15~20 parts
Chrysanthemum, 14~23 parts of matrimony vine, 13~25 parts of Schisandra chinensis and 1~6 part of donkey-hide gelatin.
Mulberries：It is cold in nature, it is sweet in flavor, sour.The thoughts of returning home, liver, kidney channel.It enriches blood enriching yin, fluid dryness.For dizziness and tinnitus, palpitaition is lost
Dormancy, poliosis, constipation, injury thirst, Heat Diabetes, blood deficiency and constipation, tonifying liver, kidney-nourishing relieve dizziness, high fever, infantile convulsions, epilepsy, etc., and grow liquid, control liver-kidney Yin deficiency.
Mulberry leaf：It is bitter, sweet, it is cold in nature.Return lung, Liver Channel.Dispelling wind and heat from the body, clearing away the lungheat and moisturizing, flat liver improving eyesight, cooling blood and hemostasis.For
Anemopyretic cold, warm disease is from the beginning of cough with lung heat, liver-yang hyperactivity dizziness, hot eyes is dim-sighted, and the hemoptysis of blood-heat bleeding is spitted blood.
Chrysanthemum：Bitter, sweet, cold nature.Return lung, Liver Channel.Relieve heat heat-clearing, flat liver improving eyesight are clearing heat and detoxicating.
Matrimony vine：It is sweet in flavor, it is mild-natured；Return liver and kidney channel.Tonifying kidney and benefiting sperm, the effect of nourishing the liver to improve visual acuity.For the deficiency of liver-yin and kidney-yin, waist and knee acid
Soft, vertigo, hypopsia is quenched one's thirst, seminal emission.
Schisandra chinensis：It is sour, it is warm-natured.Return lung, kidney, the heart channel of Hang-Shaoyin.It astringes the lung, nourshing kidney is promoted the production of body fluid, and sweat, puckery essence are received.It breathes with cough for the deficiency syndrome of the lung,
Thirst, spontaneous perspiration, night sweat, internal lesion caused by overexertion is thin thin, emission, protracted dysentery and diarrhea.
Donkey-hide gelatin：It is sweet in flavor, it is mild-natured.Return lung, liver and kidney channel.It enriches blood enriching yin, moisturizes, stop blooding.For blood deficiency chlorosis, dizziness palpitaition,
Dysphoria and insomnia, xeropulmonary cough.
The effect of Chinese medicine composition selects above-mentioned formula to be combined, can make each taste medicine generates synergistic effect, has and reconciles
Negative and positive, the effect of nourishing heart nourishing the liver can be used for keeping gentle constitution, keep its energetic, and resistance is strong, prevent the generation of disease,
And then promote the improvement of sleep quality.And Chinese medical extract dosage is less, will not destroy the trophic structure of original composition,
And it not will produce peculiar smell sense.
Wherein, the preparation method of the blackberry, blueberry composition for improving sleep quality includes the following steps：
Step 1, the preparation of blackberry extract：The blackberry, blueberry cleaned up is placed in refiner, addition weight is blackberry, blueberry 5-8
Times ethanol solution, homogenate extraction, obtain filtrate, will filtrate carry out ultrasonic extraction after centrifuge, collect centrifugate, to centrifugate into
Row distillation collects the fraction at 45~55 DEG C to get blackberry extract；Wherein, distillation pressure 170Mpa, ultrasonic extraction
Temperature is 35~40 DEG C, ultrasonic power 150W, and the time of ultrasonic extraction is 50~80min.
Step 2, the preparation of termite extract：It captures wild termite and carries out cleaning and sterilizing, impregnated with acetone solution, centrifuged
Go out acetone leaching liquor, carrying out recycling drying to acetone leaching liquor obtains termite extract.Specifically, extraction when acetone weight
It it is 4-6 times of termite weight, extraction time is 48-72 hours, and extraction temperature is 25-28 DEG C.
Step 3：By blackberry extract, Semen Phaseoli extract, Semen Nelumbinis extract, Bulbus Lilii extract, Semen Sesami Nigrum extract, dragon
Eye meat extract, termite extract and jujube extraction are spare after being weighed according to each plant demand；1~3 can also be added in the step
The Chinese medical extract of part, the Chinese medical extract includes the raw material components of following parts by weight：10~30 parts of mulberries, 5~15
The mulberry leaf, 15~20 parts of chrysanthemum, 14~23 parts of matrimony vine, 13~25 parts of Schisandra chinensis and 1~6 part of donkey-hide gelatin of part.Chinese medicine carries
Object is taken to be prepared via a method which：Medicinal powder is made through drying, crushing in each raw material, the ethyl alcohol for being 40~65% with percent by volume
Then the medicinal powder ultrasonic extraction, centrifugation, concentration is dried in solution in vacuum drying chamber, temperature parameter is 75 DEG C~80
DEG C, vacuum degree obtains Chinese medical extract between negative pressure 0.08Mpa and negative pressure 0.1Mpa.
Step 4, all raw materials in step 3 are uniformly mixed, according to common process be added customary adjuvant be made concentrate,
Fruit juice, pulp, dry powder, capsule or tablet.
Embodiment 1：
A kind of blackberry, blueberry composition for improving sleep quality includes the raw material components of following parts by weight：45 parts black
Certain kind of berries extract, 13 parts of Semen Phaseoli extract, 7 parts of Semen Nelumbinis extract, 1 part of Bulbus Lilii extract, the extraction of 1 part of Semen sesami nigrum
Object, 2 parts of Arillus Longan extract, 1 part of termite extract and 3 parts of Fructus Jujubae extract.
Preparation method is as follows：
Step 1, the preparation of blackberry extract：The blackberry, blueberry cleaned up is placed in refiner, addition weight is 5 times of blackberry, blueberry
Ethanol solution, homogenate extraction, obtain filtrate, will filtrate carry out ultrasonic extraction after centrifuge, collect centrifugate, to centrifugate carry out
Distillation collects the fraction at 45~55 DEG C to get blackberry extract；Wherein, distillation pressure 170Mpa, the temperature of ultrasonic extraction
Degree is 35 DEG C, ultrasonic power 150W, and the time of ultrasonic extraction is 50min.
Step 2, the preparation of termite extract：It captures wild termite and carries out cleaning and sterilizing, impregnated with acetone solution, centrifuged
Go out acetone leaching liquor, carrying out recycling drying to acetone leaching liquor obtains termite extract.Specifically, extraction when acetone weight
It it is 4 times of white weight, extraction time is 72 hours, and extraction temperature is 28 DEG C.
Step 3：By blackberry extract, Semen Phaseoli extract, Semen Nelumbinis extract, Bulbus Lilii extract, Semen Sesami Nigrum extract, dragon
Eye meat extract, termite extract and jujube extraction are spare after being weighed according to each plant demand.
Step 4, all raw materials in step 3 are uniformly mixed, according to common process be added customary adjuvant be made concentrate,
Fruit juice, pulp, dry powder, capsule or tablet.
Embodiment 2：
A kind of blackberry, blueberry composition for improving sleep quality includes the raw material components of following parts by weight：90 parts black
Certain kind of berries extract, 35 parts of Semen Phaseoli extract, 19 parts of Semen Nelumbinis extract, 5 parts of Bulbus Lilii extract, the extraction of 5 parts of Semen sesami nigrum
Object, 5 parts of Arillus Longan extract, 3 parts of termite extract and 7 parts of Fructus Jujubae extract.
Preparation method is as follows：
Step 1, the preparation of blackberry extract：The blackberry, blueberry cleaned up is placed in refiner, addition weight is 8 times of blackberry, blueberry
Ethanol solution, homogenate extraction, obtain filtrate, will filtrate carry out ultrasonic extraction after centrifuge, collect centrifugate, to centrifugate carry out
Distillation collects the fraction at 45~55 DEG C to get blackberry extract；Wherein, distillation pressure 170Mpa, the temperature of ultrasonic extraction
Degree is 40 DEG C, ultrasonic power 150W, and the time of ultrasonic extraction is 80min.
Step 2, the preparation of termite extract：It captures wild termite and carries out cleaning and sterilizing, impregnated with acetone solution, centrifuged
Go out acetone leaching liquor, carrying out recycling drying to acetone leaching liquor obtains termite extract.Specifically, extraction when acetone weight
It it is 6 times of termite weight, extraction time is 48 hours, and extraction temperature is 25 DEG C.
Step 3：By blackberry extract, Semen Phaseoli extract, Semen Nelumbinis extract, Bulbus Lilii extract, Semen Sesami Nigrum extract, dragon
Eye meat extract, termite extract and jujube extraction are spare after being weighed according to each plant demand.
Step 4, all raw materials in step 3 are uniformly mixed, according to common process be added customary adjuvant be made concentrate,
Fruit juice, pulp, dry powder, capsule or tablet.
Embodiment 3：
A kind of blackberry, blueberry composition for improving sleep quality includes the raw material components of following portions by weight：55 parts black
Certain kind of berries extract, 20 parts of Semen Phaseoli extract, 10 parts of Semen Nelumbinis extract, 2 parts of Bulbus Lilii extract, the extraction of 2 parts of Semen sesami nigrum
Object, 2 parts of Arillus Longan extract, 1 part of termite extract and 4 parts of Fructus Jujubae extract.
Preparation method is as follows：
Step 1, the preparation of blackberry extract：The blackberry, blueberry cleaned up is placed in refiner, addition weight is 6 times of blackberry, blueberry
Ethanol solution, homogenate extraction, obtain filtrate, will filtrate carry out ultrasonic extraction after centrifuge, collect centrifugate, to centrifugate carry out
Distillation collects the fraction at 45~55 DEG C to get blackberry extract；Wherein, distillation pressure 170Mpa, the temperature of ultrasonic extraction
Degree is 36 DEG C, ultrasonic power 150W, and the time of ultrasonic extraction is 60min.
Step 2, the preparation of termite extract：It captures wild termite and carries out cleaning and sterilizing, impregnated with acetone solution, centrifuged
Go out acetone leaching liquor, carrying out recycling drying to acetone leaching liquor obtains termite extract.Specifically, extraction when acetone weight
It it is 5 times of white weight, extraction time is 55 hours, and extraction temperature is 27 DEG C.
Step 3：By blackberry extract, Semen Phaseoli extract, Semen Nelumbinis extract, Bulbus Lilii extract, Semen Sesami Nigrum extract, dragon
Eye meat extract, termite extract and jujube extraction are spare after being weighed according to each plant demand.
Step 4, all raw materials in step 3 are uniformly mixed, according to common process be added customary adjuvant be made concentrate,
Fruit juice, pulp, dry powder, capsule or tablet.
Embodiment 4：
A kind of blackberry, blueberry composition for improving sleep quality includes the raw material components of following portions by weight：70 parts black
Certain kind of berries extract, 30 parts of Semen Phaseoli extract, 16 parts of Semen Nelumbinis extract, 4 parts of Bulbus Lilii extract, the extraction of 4 parts of Semen sesami nigrum
Object, 4 parts of Arillus Longan extract, 3 parts of termite extract and 6 parts of Fructus Jujubae extract.
Step 1, the preparation of blackberry extract：The blackberry, blueberry cleaned up is placed in refiner, addition weight is 7 times of blackberry, blueberry
Ethanol solution, homogenate extraction, obtain filtrate, will filtrate carry out ultrasonic extraction after centrifuge, collect centrifugate, to centrifugate carry out
Distillation collects the fraction at 45~55 DEG C to get blackberry extract；Wherein, distillation pressure 170Mpa, the temperature of ultrasonic extraction
Degree is 37 DEG C, ultrasonic power 150W, and the time of ultrasonic extraction is 72min.
Step 2, the preparation of termite extract：It captures wild termite and carries out cleaning and sterilizing, impregnated with acetone solution, centrifuged
Go out acetone leaching liquor, carrying out recycling drying to acetone leaching liquor obtains termite extract.Specifically, extraction when acetone weight
It it is 5.5 times of white weight, extraction time is 60 hours, and extraction temperature is 26 DEG C.
Step 3：By blackberry extract, Semen Phaseoli extract, Semen Nelumbinis extract, Bulbus Lilii extract, Semen Sesami Nigrum extract, dragon
Eye meat extract, termite extract and jujube extraction are spare after being weighed according to each plant demand.
Step 4, all raw materials in step 3 are uniformly mixed, according to common process be added customary adjuvant be made concentrate,
Fruit juice, pulp, dry powder, capsule or tablet.
Embodiment 5：
A kind of blackberry, blueberry composition for improving sleep quality includes the raw material components of following portions by weight：60 parts black
Certain kind of berries extract, 25 parts of Semen Phaseoli extract, 13 parts of Semen Nelumbinis extract, 3 parts of Bulbus Lilii extract, the extraction of 3 parts of Semen sesami nigrum
Object, 3 parts of Arillus Longan extract, 2 parts of termite extract and 5 parts of Fructus Jujubae extract.
Preparation method is as follows：
Step 1, the preparation of blackberry extract：The blackberry, blueberry cleaned up is placed in refiner, addition weight is 7 times of blackberry, blueberry
Ethanol solution, homogenate extraction, obtain filtrate, will filtrate carry out ultrasonic extraction after centrifuge, collect centrifugate, to centrifugate carry out
Distillation collects the fraction at 45~55 DEG C to get blackberry extract；Wherein, distillation pressure 170Mpa, the temperature of ultrasonic extraction
Degree is 35 DEG C, ultrasonic power 150W, and the time of ultrasonic extraction is 65min.
Step 2, the preparation of termite extract：It captures wild termite and carries out cleaning and sterilizing, impregnated with acetone solution, centrifuged
Go out acetone leaching liquor, carrying out recycling drying to acetone leaching liquor obtains termite extract.Specifically, extraction when acetone weight
It it is 4.5 times of white weight, extraction time is 66 hours, and extraction temperature is 27 DEG C.
Step 3：By blackberry extract, Semen Phaseoli extract, Semen Nelumbinis extract, Bulbus Lilii extract, Semen Sesami Nigrum extract, dragon
Eye meat extract, termite extract and jujube extraction are spare after being weighed according to each plant demand.
Step 4, all raw materials in step 3 are uniformly mixed, according to common process be added customary adjuvant be made concentrate,
Fruit juice, pulp, dry powder, capsule or tablet.
Embodiment 6：
A kind of blackberry, blueberry composition for improving sleep quality includes the raw material components of following portions by weight：60 parts black
Certain kind of berries extract, 25 parts of Semen Phaseoli extract, 13 parts of Semen Nelumbinis extract, 3 parts of Bulbus Lilii extract, the extraction of 3 parts of Semen sesami nigrum
Object, 3 parts of Arillus Longan extract, 2 parts of termite extract, 5 parts of Fructus Jujubae extract and 1 part of Chinese medical extract.Chinese medicine carries
It includes the raw material components of following parts by weight to take object：30 parts of mulberries, 15 parts of mulberry leaf, 20 parts of chrysanthemum, 23 parts of matrimony vine, 25
The Schisandra chinensis of part and 6 parts of donkey-hide gelatin.
Preparation method is as follows：
Step 1, the preparation of blackberry extract：The blackberry, blueberry cleaned up is placed in refiner, addition weight is 6 times of blackberry, blueberry
Ethanol solution, homogenate extraction, obtain filtrate, will filtrate carry out ultrasonic extraction after centrifuge, collect centrifugate, to centrifugate carry out
Distillation collects the fraction at 45~55 DEG C to get blackberry extract；Wherein, distillation pressure 170Mpa, the temperature of ultrasonic extraction
Degree is 39 DEG C, ultrasonic power 150W, and the time of ultrasonic extraction is 71min.
Step 2, the preparation of termite extract：It captures wild termite and carries out cleaning and sterilizing, impregnated with acetone solution, centrifuged
Go out acetone leaching liquor, carrying out recycling drying to acetone leaching liquor obtains termite extract.Specifically, extraction when acetone weight
It it is 5 times of termite weight, extraction time is 60 hours, and extraction temperature is 27 DEG C.
Step 3：The preparation of Chinese medical extract：Medicinal powder is made through drying, crushing in each raw material, is 40% with percent by volume
Ethanol solution to the medicinal powder ultrasonic extraction, centrifugation, concentration, be then dried in vacuum drying chamber, temperature parameter 80
DEG C, vacuum degree obtains Chinese medical extract between negative pressure 0.08Mpa and negative pressure 0.1Mpa.
Step 4：By blackberry extract, Semen Phaseoli extract, Semen Nelumbinis extract, Bulbus Lilii extract, Semen Sesami Nigrum extract, dragon
Eye meat extract, termite extract, Chinese medical extract and jujube extraction are spare after being weighed according to each plant demand.
Step 5, all raw materials in step 4 are uniformly mixed, according to common process be added customary adjuvant be made concentrate,
Fruit juice, pulp, dry powder, capsule or tablet.
Embodiment 7：
A kind of blackberry, blueberry composition for improving sleep quality includes the raw material components of following portions by weight：60 parts black
Certain kind of berries extract, 25 parts of Semen Phaseoli extract, 13 parts of Semen Nelumbinis extract, 3 parts of Bulbus Lilii extract, the extraction of 3 parts of Semen sesami nigrum
Object, 3 parts of Arillus Longan extract, 2 parts of termite extract, 5 parts of Fructus Jujubae extract and 3 parts of Chinese medical extract.Chinese medicine carries
It includes the raw material components of following parts by weight to take object：10 parts of mulberries, 5 parts of mulberry leaf, 15 parts of chrysanthemum, 14 parts of matrimony vine, 13
The Schisandra chinensis of part and 1 part of donkey-hide gelatin.
Preparation method is as follows：
Step 1, the preparation of blackberry extract：The blackberry, blueberry cleaned up is placed in refiner, addition weight is 7 times of blackberry, blueberry
Ethanol solution, homogenate extraction, obtain filtrate, will filtrate carry out ultrasonic extraction after centrifuge, collect centrifugate, to centrifugate carry out
Distillation collects the fraction at 45~55 DEG C to get blackberry extract；Wherein, distillation pressure 170Mpa, the temperature of ultrasonic extraction
Degree is 36 DEG C, ultrasonic power 150W, and the time of ultrasonic extraction is 60min.
Step 2, the preparation of termite extract：It captures wild termite and carries out cleaning and sterilizing, impregnated with acetone solution, centrifuged
Go out acetone leaching liquor, carrying out recycling drying to acetone leaching liquor obtains termite extract.Specifically, extraction when acetone weight
It it is 5 times of termite weight, extraction time is 65 hours, and extraction temperature is 26 DEG C.
Step 3：The preparation of Chinese medical extract：Medicinal powder is made through drying, crushing in each raw material, is 65% with percent by volume
Ethanol solution to the medicinal powder ultrasonic extraction, centrifugation, concentration, be then dried in vacuum drying chamber, temperature parameter 75
DEG C, vacuum degree obtains Chinese medical extract between negative pressure 0.08Mpa and negative pressure 0.1Mpa.
Step 4：By blackberry extract, Semen Phaseoli extract, Semen Nelumbinis extract, Bulbus Lilii extract, Semen Sesami Nigrum extract, dragon
Eye meat extract, termite extract, Chinese medical extract and jujube extraction are spare after being weighed according to each plant demand.
Step 5, all raw materials in step 4 are uniformly mixed, according to common process be added customary adjuvant be made concentrate,
Fruit juice, pulp, dry powder, capsule or tablet.
Experimental example 1：For improving influence of the blackberry, blueberry composition of sleep quality to mouse sleep time
Experiment material
1, animal：SPF grades of ICR mouse, half male and half female, 18~22g of weight.
2, articles for use：The embodiment of the present invention 1 to 7 is used to improve the blackberry, blueberry composition of sleep quality, commercially available sedative health-care product.
3, experimental method
Select 18~22g mouse 80, half male and half female is randomly divided into 8 groups by gender and weight, respectively 1 group of control group,
7 groups of test groups (embodiment 1 to 7).In addition to control group, remaining each group mouse gives corresponding embodiment 1 to 7 by 2g/kg every time
The blackberry, blueberry composition for improving sleep quality carry out gavage, 3 times a day, continuous 20d, control group gives the commercially available of equal capacity
Sedative health-care product gavage.After continuous gavage 20d, last gavage 1h, yellow Jackets 50mg/kg is injected intraperitoneally, observation mouse turns over
Normal reflection disappears and recovery time, records sleep time, observes 2h altogether, sleeping time is calculated more than 2h person with 2h.Experiment
It the results are shown in Table 1.
Influence experimental result of the table 1 to mouse sleep time
| Grouping | Size of animal | Sleeping time/min |
| Control group | 10 | 67±10.3 |
| Embodiment 1 | 10 | 87±11.3** |
| Embodiment 2 | 10 | 95±16.0** |
| Embodiment 3 | 10 | 100±12.2** |
| Embodiment 4 | 10 | 95±16.1** |
| Embodiment 5 | 10 | 110±13.8** |
| Embodiment 6 | 10 | 102±15.7** |
| Embodiment 7 | 10 | 111±13.8** |
* * P ＜ 0.01 compared with the control group.
The result shows that：The present invention can obviously increase the sleeping time of mouse for improving the blackberry, blueberry composition of sleep quality,
Embodiment 1 to 7 has the difference (P ＜ 0.01) of pole conspicuousness compared with the control group.As it can be seen that the present invention is for improving sleep quality
Blackberry, blueberry composition is stronger than the hypnosis sedative action of commercially available sedative health-care product.
The foregoing is only a preferred embodiment of the present invention, is not intended to restrict the invention, for the skill of this field
For art personnel, the invention may be variously modified and varied.All within the spirits and principles of the present invention, any made by repair
Change, equivalent replacement, improvement etc., should all be included in the protection scope of the present invention.
Claims (10)
1. a kind of blackberry, blueberry composition for improving sleep quality, which is characterized in that include the raw material components of following parts by weight：
45~90 parts of blackberry extract, 13~35 parts of Semen Phaseoli extract, 7~19 parts of Semen Nelumbinis extract, 1~5 part of lily
Extract, 1-5 parts of Semen Sesami Nigrum extract, 2~5 parts of Arillus Longan extract, 1~3 part of termite extract and 3-7 parts it is big
Jujube extract.
2. the blackberry, blueberry composition according to claim 1 for improving sleep quality, which is characterized in that including following weight
The raw material components of number：55~70 parts of blackberry extract, 20~30 parts of Semen Phaseoli extract, the extraction of 10~16 parts of lotus seeds
Object, 2~4 parts of Bulbus Lilii extract, 2-4 parts of Semen Sesami Nigrum extract, 2~4 parts of Arillus Longan extract, 1~3 part of termite carry
Take object and 4-6 parts of Fructus Jujubae extract.
3. the blackberry, blueberry composition according to claim 1 for improving sleep quality, which is characterized in that including following weight
The raw material components of number：60 parts of blackberry extract, 25 parts of Semen Phaseoli extract, 13 parts of Semen Nelumbinis extract, 3 parts of lily
Extract, 3 parts of Semen Sesami Nigrum extract, 3 parts of Arillus Longan extract, 2 parts of termite extract and 5 parts of Fructus Jujubae extract.
4. being used to improve the blackberry, blueberry composition of sleep quality according to claims 1 to 3 any one of them, which is characterized in that also
Include 1~3 part of Chinese medical extract, the Chinese medical extract includes the raw material components of following parts by weight：10~30 parts of mulberry
Shen, 5~15 parts of mulberry leaf, 15~20 parts of chrysanthemum, 14~23 parts of matrimony vine, 13~25 parts of Schisandra chinensis and 1~6 part Ah
Glue.
5. the blackberry, blueberry composition according to claim 4 for improving sleep quality, which is characterized in that in the combination
The product form of object is concentrate, fruit juice, jam, capsule, tablet or dry powder.
6. a kind of preparation method as described in any one of claims 1 to 3 for improving the blackberry, blueberry composition of sleep quality,
It is characterized in that, this method comprises the following steps：
Step 1, the preparation of blackberry extract：The blackberry, blueberry cleaned up is placed in refiner, it is 5-8 times of blackberry, blueberry that weight, which is added,
Ethanol solution, homogenate extraction, obtains filtrate, is centrifuged after filtrate is carried out ultrasonic extraction, collects centrifugate, is steamed to centrifugate
It evaporates, collects the fraction at 45~55 DEG C to get blackberry extract；
Step 2, the preparation of termite extract：It captures wild termite and carries out cleaning and sterilizing, impregnated with acetone solution, centrifuge out third
Ketone leaching liquor carries out recycling drying to acetone leaching liquor and obtains termite extract.
Step 3：By blackberry extract, Semen Phaseoli extract, Semen Nelumbinis extract, Bulbus Lilii extract, Semen Sesami Nigrum extract, arillus longan
Extract, termite extract and jujube extraction are spare after being weighed according to each plant demand；
Step 4, all raw materials in step 3 are uniformly mixed, customary adjuvant, which is added, according to common process is made concentrate, fruit
Juice, pulp, dry powder, capsule or tablet.
7. the preparation method according to claim 6 for improving the blackberry, blueberry composition of sleep quality, which is characterized in that step
Distillation pressure is 170Mpa in rapid 1.
8. the preparation method according to claim 6 for improving the blackberry, blueberry composition of sleep quality, which is characterized in that step
The temperature of ultrasonic extraction is 35~40 DEG C, ultrasonic power 150W in rapid 1, and the time of ultrasonic extraction is 50~80min.
9. it is used to improve the preparation method of the blackberry, blueberry composition of sleep quality according to claim 6-8 any one of them, it is special
Sign is, in the blending process of the step 3, is also added with 1~3 part of Chinese medical extract, the Chinese medical extract includes
The raw material components of following parts by weight：10~30 parts of mulberries, 5~15 parts of mulberry leaf, 15~20 parts of chrysanthemum, 14~23 parts
Matrimony vine, 13~25 parts of Schisandra chinensis and 1~6 part of donkey-hide gelatin.
10. the preparation method of the alimentation composition of nourishing heart according to claim 8, which is characterized in that the Chinese medicine carries
Object is taken to be prepared via a method which：
Medicinal powder is made through drying, crushing in each raw material, the ethanol solution for being 40~65% with percent by volume is super to the medicinal powder
Sound extraction, centrifugation, concentration, are then dried in vacuum drying chamber, and temperature parameter is 75 DEG C~80 DEG C, and vacuum degree is in negative pressure
Between 0.08Mpa and negative pressure 0.1Mpa, Chinese medical extract is obtained.
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| CN114631545A (en) * | 2022-03-28 | 2022-06-17 | 青岛有为生物科技有限公司 | Plant source rooting agent for promoting plant rooting and preparation method thereof |
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| CN1090760A (en) * | 1993-08-23 | 1994-08-17 | 武汉市白蚁防治所 | A kind of production method of health care medicine Coptotermes formosanus Shtrari. dry powder |
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| CN102652560A (en) * | 2011-05-04 | 2012-09-05 | 河南省益群生物科技有限公司 | Health-care food |
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| CN106581615A (en) * | 2016-11-28 | 2017-04-26 | 安徽国顺中药发展有限公司 | Sleep-promoting health-preserving chrysanthemum tea and making method thereof |
| CN106616955A (en) * | 2015-11-02 | 2017-05-10 | 邹波 | Making method of health-care product capable of improving sleep |
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| CN1090760A (en) * | 1993-08-23 | 1994-08-17 | 武汉市白蚁防治所 | A kind of production method of health care medicine Coptotermes formosanus Shtrari. dry powder |
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| CN102652560A (en) * | 2011-05-04 | 2012-09-05 | 河南省益群生物科技有限公司 | Health-care food |
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| CN106616955A (en) * | 2015-11-02 | 2017-05-10 | 邹波 | Making method of health-care product capable of improving sleep |
| CN106343560A (en) * | 2016-08-26 | 2017-01-25 | 北京徳弘东方健康科技有限公司 | Nutrient composition and making method and application thereof |
| CN106581615A (en) * | 2016-11-28 | 2017-04-26 | 安徽国顺中药发展有限公司 | Sleep-promoting health-preserving chrysanthemum tea and making method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN114631545A (en) * | 2022-03-28 | 2022-06-17 | 青岛有为生物科技有限公司 | Plant source rooting agent for promoting plant rooting and preparation method thereof |
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