CN108434402A - Chinese medicine composition and preparation method thereof for treating artery sclerosis - Google Patents
Chinese medicine composition and preparation method thereof for treating artery sclerosis Download PDFInfo
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Abstract
The present invention relates to a kind of Chinese medicine compositions and preparation method thereof for treating artery sclerosis.The raw material of Chinese medicine composition includes Cassia occidentalis, SEMEN PINI KORAIENSIS, hawthorn, giant knotweed, Cortex Eucommiae, grass-leaved sweetflag, American Ginseng, fructus alpiniae oxyphyllae, beggar-ticks, Rhizoma Chuanxiong, rhizoma alismatis, pueraria lobata, leech, radix achyranthis bidentatae, the tuber of pinellia, the stem of noble dendrobium, Radix Salviae Miltiorrhizae, Ramulus euonymi, Rhizoma Gastrodiae, Morinda officinalis, the dried immature fruit of citron orange, matrimony vine, seven leaf courages, Radix Curcumae, red yeast rice and black fungus.Preparation method：It is soaked after each raw material component is crushed；Extraction is decocted later, is condensed into medicinal extract, is obtained Chinese medicine composition.Chinese medicine composition provided by the invention has excellent qi-regulating promoting circulation of blood, promoting blood circulation and removing blood stasis and softening and resolving hard mass and other effects, can significantly improve the symptoms such as palpitaition, pectoralgia, uncomfortable in chest, headache and dizzy and the cool fiber crops of four limbs of arteriosclerotic, and safe without toxic side effect；In addition, Chinese medicine composition provided by the invention is easy to use, cost is relatively low, has good commercial promise.
Description
Technical field
The present invention relates to field of Chinese herbal medicine technology, and in particular to it is a kind of for treat artery sclerosis Chinese medicine composition and its
Preparation method.
Background technology
A kind of non-inflammation lesion of the artery sclerosis as artery, can make ductus arteriosus wall thicken, be hardened, follow the string, manage
Chamber is narrow.Artery sclerosis is with age and the vascular diseases of appearance, rule typically occur in adolescence, until
Person in middle and old age's period aggravates, falls ill.Male is more compared with women, this disease gradually increases in China in recent years, and it is dead main to become the elderly
One of reason.
Currently, the treatment means of such disease mostly based on western medicine, such as prevent the drug master of artery sclerosis, coronary heart disease
There are lipid-regulation medicine such as Statins, cholic acid integrated agent and cholesterol absorption inhibitor, fibrates and niacin class etc., antiplatelet drug
Object such as aspirin, thienopyridine analog derivative clopidogrel, ticlopidine, anticoagulant such as unfractionated heparin and low molecule matter
Amount heparin, direct thrombin inhibitor hirudin, argatroban and ratio cut down Lu's pyridine etc., also angiotensin converting enzyme inhibitor
Ramipril, Perindopril, beta-blocker, calcium ion antagonist and nitrate esters medicine, aldosterone receptor antagonist according to
Puli's ketone, K ~+Channel Opener nicorandil etc..However, though above-mentioned various kinds of drug has certain curative effect, it is often accompanied by
Apparent side effect；The headache as caused by blood vessel dilatation, low blood pressure reflex tachycardia, dry, abdominal distension or constipation etc..
Based on this, study a kind of novel, safe without toxic side effect and can effectively, the treatment of safety or to alleviate artery hard
The drug of change has very important significance.
Invention content
For the defects in the prior art, the present invention is intended to provide it is a kind of for treat artery sclerosis Chinese medicine composition and
Preparation method.Chinese medicine composition provided by the invention has excellent qi-regulating promoting circulation of blood, promoting blood circulation and removing blood stasis and softening and resolving hard mass and other effects,
The symptoms such as palpitaition, pectoralgia, uncomfortable in chest, headache and dizzy and the cool fiber crops of four limbs of arteriosclerotic are can significantly improve, and safe and non-toxic
Side effect；In addition, Chinese medicine composition provided by the invention is easy to use, cost is relatively low, has good commercial promise.
For this purpose, the present invention provides the following technical solutions：
In a first aspect, the present invention provides a kind of Chinese medicine composition for treating artery sclerosis, raw material components are by weight
Meter, including：10~15 parts by weight of Cassia occidentalis, 20~25 parts by weight of SEMEN PINI KORAIENSIS, 20~30 parts by weight of hawthorn, 20~25 weight of giant knotweed
Part, 20~30 parts by weight of Cortex Eucommiae, 30~50 parts by weight of grass-leaved sweetflag, 30~40 parts by weight of American Ginseng, 10~15 parts by weight of fructus alpiniae oxyphyllae,
15~25 parts by weight of Rhizoma Chuanxiong, 15~20 parts by weight of rhizoma alismatis, 25~30 parts by weight of pueraria lobata, 10~15 parts by weight of leech, the stem of noble dendrobium 15~
20 parts by weight, 20~30 parts by weight of Radix Salviae Miltiorrhizae, 10~15 parts by weight of Ramulus euonymi, 20~30 parts by weight of Rhizoma Gastrodiae, 15~20 weight of Morinda officinalis
Measure part, 15~20 parts by weight of the dried immature fruit of citron orange, 25~35 parts by weight of matrimony vine, 15~25 parts by weight of Radix Curcumae, 10~15 parts by weight of red yeast rice and black
15~25 parts by weight of agaric.
Preferably, the raw material components of Chinese medicine composition further include：10~25 parts by weight of beggar-ticks, seven leaf courages, 10~25 weight
Part, 10~15 parts by weight of 10~15 parts by weight of the tuber of pinellia and radix achyranthis bidentatae.
Preferably, Chinese medicine composition is made of following raw material components：15 parts by weight of Cassia occidentalis, 20 parts by weight of SEMEN PINI KORAIENSIS, mountain
30 parts by weight of short, bristly hair or beard, 20 parts by weight of giant knotweed, 30 parts by weight of Cortex Eucommiae, 30 parts by weight of grass-leaved sweetflag, 40 parts by weight of American Ginseng, 10 weight of fructus alpiniae oxyphyllae
Measure part, 25 parts by weight of beggar-ticks, 15 parts by weight of Rhizoma Chuanxiong, 20 parts by weight of rhizoma alismatis, 25 parts by weight of pueraria lobata, 15 parts by weight of leech, bosom ox
10 parts by weight of knee, 15 parts by weight of the tuber of pinellia, 15 parts by weight of the stem of noble dendrobium, 30 parts by weight of Radix Salviae Miltiorrhizae, 10 parts by weight of Ramulus euonymi, 30 weight of Rhizoma Gastrodiae
Part, 15 parts by weight of Morinda officinalis, 20 parts by weight of the dried immature fruit of citron orange, 25 parts by weight of matrimony vine, seven leaf courages, 25 parts by weight, 15 parts by weight of Radix Curcumae, red yeast rice
15 parts by weight of 15 parts by weight and black fungus.
Preferably, Chinese medicine composition is made of following raw material components：10 parts by weight of Cassia occidentalis, 25 parts by weight of SEMEN PINI KORAIENSIS, mountain
20 parts by weight of short, bristly hair or beard, 25 parts by weight of giant knotweed, 20 parts by weight of Cortex Eucommiae, 50 parts by weight of grass-leaved sweetflag, 30 parts by weight of American Ginseng, 15 weight of fructus alpiniae oxyphyllae
Measure part, 10 parts by weight of beggar-ticks, 25 parts by weight of Rhizoma Chuanxiong, 15 parts by weight of rhizoma alismatis, 30 parts by weight of pueraria lobata, 10 parts by weight of leech, bosom ox
15 parts by weight of knee, 10 parts by weight of the tuber of pinellia, 20 parts by weight of the stem of noble dendrobium, 20 parts by weight of Radix Salviae Miltiorrhizae, 15 parts by weight of Ramulus euonymi, 20 weight of Rhizoma Gastrodiae
Part, 20 parts by weight of Morinda officinalis, 15 parts by weight of the dried immature fruit of citron orange, 35 parts by weight of matrimony vine, seven leaf courages, 10 parts by weight, 25 parts by weight of Radix Curcumae, red yeast rice
25 parts by weight of 10 parts by weight and black fungus.
Second aspect, the present invention provide a kind of preparation method of Chinese medicine composition, include the following steps：S101：In proportion
Each raw material component is weighed, crushes after cleaning, soaks later；S102：Boil the drug use after immersion by intense fire 3~
8min, then exchange of notes fire heat 50~80min, filter and collect filtrate；S103：Relative density is when filtrate is condensed into 70 DEG C
1.10~1.20 medicinal extract, obtains Chinese medicine composition.
Preferably, in S101, the water of addition is 5~15 times of raw material components gross mass, soaking time be 20min~
30min。
Preferably, in S101, each raw material component is crushed to 60~100 mesh.
It can pharmaceutically be connect it should be noted that Chinese medicine composition prepared by the above method can be further prepared into as needed
The dosage form received.In addition, also belonging to protection scope of the present invention as drug made of active constituent using above-mentioned Chinese medicine composition.Pass through
It by above-mentioned Chinese medicine composition, is prepared after directly preparing or being added pharmaceutically acceptable auxiliary material, can be made into and any pharmaceutically may be used
The dosage form of receiving.Include by taking external preparation as an example：Solution, patch, vina, tincture, gelling agent, liniment, aerosol, spraying
Agent, ointment, suppository and plastics.The drug of above-mentioned various dosage forms can be prepared according to the conventional method of pharmaceutical field.
In clinical application, the dosage of Chinese medicine composition provided by the invention is generally each 2g, three times a day.
The third aspect, Chinese medicine composition provided by the invention are preparing treatment atherosclerosis drug and/or medicated premix
In application.
The above technical solution of the present invention has the following advantages over the prior art：
(1) applicant has found by numerous studies：Chinese medicine composition provided by the invention has excellent qi-regulating promoting circulation of blood, work
Blood stagnation resolvation and softening and resolving hard mass and other effects can significantly improve the palpitaition, pectoralgia, uncomfortable in chest, headache and dizzy and four of arteriosclerotic
The symptoms such as the cool fiber crops of limb, and safe without toxic side effect；In addition, Chinese medicine composition provided by the invention is easy to use, cost is relatively low, tool
There is good commercial promise.
(2) preparation method provided by the invention is used, the same of each bulk pharmaceutical chemicals active constituent can retained to greatest extent
When, the active ingredient in each raw medicinal material can be fully released, to make the Chinese medicine composition being finally prepared not
Only there is good drug effect, and be easy to absorb, and then be rapidly achieved the purpose for improving artery sclerosis.
The additional aspect and advantage of the present invention will be set forth in part in the description, and will partly become from the following description
Obviously, or practice through the invention is recognized.
Specific implementation mode
The embodiment of technical solution of the present invention will be described in detail below.Following embodiment is only used for clearer
Illustrate technical scheme of the present invention, therefore be only used as example, and not intended to limit the protection scope of the present invention.
Experimental method in following embodiments is unless otherwise specified conventional method.
Test material as used in the following examples is unless otherwise specified to be commercially available from conventional reagent shop.
Quantitative test in following embodiment, is respectively provided with three repeated experiments, and data are the average value of three repeated experiments
Or mean+SD.
Cassia occidentalis as used in the following examples, SEMEN PINI KORAIENSIS, hawthorn, giant knotweed, Cortex Eucommiae, grass-leaved sweetflag, American Ginseng, fructus alpiniae oxyphyllae,
Beggar-ticks, Rhizoma Chuanxiong, rhizoma alismatis, pueraria lobata, leech, radix achyranthis bidentatae, the tuber of pinellia, the stem of noble dendrobium, Radix Salviae Miltiorrhizae, Ramulus euonymi, Rhizoma Gastrodiae, Morinda officinalis, the dried immature fruit of citron orange, Qi
Son, seven leaf courages, Radix Curcumae, red yeast rice and black fungus meet the related rule under each medicinal material item of text of Chinese Pharmacopoeia (version in 2017)
It is fixed.Before feeding intake, by identification, ingredients material object is consistent with title, and quality complies with standard.
The present invention provides a kind of Chinese medicine composition for treating artery sclerosis, which is characterized in that raw material components are by weight
Part meter, including：10~15 parts by weight of Cassia occidentalis, 20~25 parts by weight of SEMEN PINI KORAIENSIS, 20~30 parts by weight of hawthorn, 20~25 weight of giant knotweed
Measure part, 20~30 parts by weight of Cortex Eucommiae, 30~50 parts by weight of grass-leaved sweetflag, 30~40 parts by weight of American Ginseng, 10~15 weight of fructus alpiniae oxyphyllae
Part, 15~25 parts by weight of Rhizoma Chuanxiong, 15~20 parts by weight of rhizoma alismatis, 25~30 parts by weight of pueraria lobata, 10~15 parts by weight of leech, the stem of noble dendrobium 15
~20 parts by weight, 20~30 parts by weight of Radix Salviae Miltiorrhizae, 10~15 parts by weight of Ramulus euonymi, 20~30 parts by weight of Rhizoma Gastrodiae, Morinda officinalis 15~20
Parts by weight, 15~20 parts by weight of the dried immature fruit of citron orange, 25~35 parts by weight of matrimony vine, 15~25 parts by weight of Radix Curcumae, 10~15 parts by weight of red yeast rice and
15~25 parts by weight of black fungus；And raw material components preferably further include 10~25 parts by weight of beggar-ticks, seven leaf courages, 10~25 parts by weight,
10~15 parts by weight of 10~15 parts by weight of the tuber of pinellia and radix achyranthis bidentatae.
In addition, for the Chinese medicine composition of the present invention, the present invention specially devises preparation method, includes the following steps：
S101：Each raw material component is weighed in proportion, is crushed after cleaning, is soaked later.
S102：Boil the drug use after immersion by intense fire 3~8min, then exchange of notes fire heats 50~80min, filters and receives
Collect filtrate.
S103：The medicinal extract that relative density is 1.10~1.20 when filtrate is condensed into 70 DEG C, obtains Chinese medicine composition.
It illustrates With reference to embodiment：
Embodiment one
The present embodiment provides a kind of Chinese medicine compositions for treating artery sclerosis, are prepared by following raw material components：
15 parts by weight of Cassia occidentalis, 20 parts by weight of SEMEN PINI KORAIENSIS, 30 parts by weight of hawthorn, 20 parts by weight of giant knotweed, 30 parts by weight of Cortex Eucommiae, grass-leaved sweetflag 30
Parts by weight, 40 parts by weight of American Ginseng, 10 parts by weight of fructus alpiniae oxyphyllae, 15 parts by weight of Rhizoma Chuanxiong, 20 parts by weight of rhizoma alismatis, 25 parts by weight of pueraria lobata,
15 parts by weight of leech, 15 parts by weight of the stem of noble dendrobium, 30 parts by weight of Radix Salviae Miltiorrhizae, 10 parts by weight of Ramulus euonymi, 30 parts by weight of Rhizoma Gastrodiae, 15 weight of Morinda officinalis
Measure part, 20 parts by weight of the dried immature fruit of citron orange, 25 parts by weight of matrimony vine, 15 parts by weight of 15 parts by weight of Radix Curcumae, 15 parts by weight of red yeast rice and black fungus.
By above-mentioned raw materials component, preparation method using the present invention prepares Chinese medicine composition：
S101：Each raw material component is weighed in proportion, is crushed to 100 mesh after cleaning, is soaked later.Wherein, addition
Water is 8 times of raw material components gross mass, soaking time 30min.
S102：Boil the drug use after immersion by intense fire 3min, then exchange of notes fire heats 80min, filters and collects filtrate.
S103：The medicinal extract that relative density is 1.15 when filtrate is condensed into 70 DEG C, obtains Chinese medicine composition.
Embodiment two
The present embodiment provides a kind of Chinese medicine compositions for treating artery sclerosis, are prepared by following raw material components：
10 parts by weight of Cassia occidentalis, 25 parts by weight of SEMEN PINI KORAIENSIS, 20 parts by weight of hawthorn, 25 parts by weight of giant knotweed, 20 parts by weight of Cortex Eucommiae, grass-leaved sweetflag 50
Parts by weight, 30 parts by weight of American Ginseng, 15 parts by weight of fructus alpiniae oxyphyllae, 25 parts by weight of Rhizoma Chuanxiong, 15 parts by weight of rhizoma alismatis, 30 parts by weight of pueraria lobata,
10 parts by weight of leech, 20 parts by weight of the stem of noble dendrobium, 20 parts by weight of Radix Salviae Miltiorrhizae, 15 parts by weight of Ramulus euonymi, 20 parts by weight of Rhizoma Gastrodiae, 20 weight of Morinda officinalis
Measure part, 15 parts by weight of the dried immature fruit of citron orange, 35 parts by weight of matrimony vine, 25 parts by weight of 25 parts by weight of Radix Curcumae, 10 parts by weight of red yeast rice and black fungus.
By above-mentioned raw materials component, preparation method using the present invention prepares Chinese medicine composition：
S101：Each raw material component is weighed in proportion, is crushed to 60 mesh after cleaning, is soaked later.Wherein, the water of addition
Amount is 15 times of raw material components gross mass, soaking time 20min.
S102：Boil the drug use after immersion by intense fire 8min, then exchange of notes fire heats 50min, filters and collects filtrate.
S103：The medicinal extract that relative density is 1.20 when filtrate is condensed into 70 DEG C, obtains Chinese medicine composition.
Embodiment three
The present embodiment provides a kind of Chinese medicine compositions for treating artery sclerosis, are prepared by following raw material components：
15 parts by weight of Cassia occidentalis, 20 parts by weight of SEMEN PINI KORAIENSIS, 30 parts by weight of hawthorn, 20 parts by weight of giant knotweed, 30 parts by weight of Cortex Eucommiae, grass-leaved sweetflag 30
Parts by weight, 40 parts by weight of American Ginseng, 10 parts by weight of fructus alpiniae oxyphyllae, 25 parts by weight of beggar-ticks, 15 parts by weight of Rhizoma Chuanxiong, 20 weight of rhizoma alismatis
Part, 25 parts by weight of pueraria lobata, 15 parts by weight of leech, 10 parts by weight of radix achyranthis bidentatae, 15 parts by weight of the tuber of pinellia, 15 parts by weight of the stem of noble dendrobium, Radix Salviae Miltiorrhizae 30
Parts by weight, 10 parts by weight of Ramulus euonymi, 30 parts by weight of Rhizoma Gastrodiae, 15 parts by weight of Morinda officinalis, 20 parts by weight of the dried immature fruit of citron orange, 25 parts by weight of matrimony vine,
Seven leaf courages, 25 parts by weight, 15 parts by weight of 15 parts by weight of Radix Curcumae, 15 parts by weight of red yeast rice and black fungus.
By above-mentioned raw materials component, preparation method using the present invention prepares Chinese medicine composition：
S101：Each raw material component is weighed in proportion, is crushed to 100 mesh after cleaning, is soaked later.Wherein, addition
Water is 8 times of raw material components gross mass, soaking time 30min.
S102：Boil the drug use after immersion by intense fire 3min, then exchange of notes fire heats 80min, filters and collects filtrate.
S103：The medicinal extract that relative density is 1.15 when filtrate is condensed into 70 DEG C, obtains Chinese medicine composition.
Example IV
The present embodiment provides a kind of Chinese medicine compositions for treating artery sclerosis, are prepared by following raw material components：
10 parts by weight of Cassia occidentalis, 25 parts by weight of SEMEN PINI KORAIENSIS, 20 parts by weight of hawthorn, 25 parts by weight of giant knotweed, 20 parts by weight of Cortex Eucommiae, grass-leaved sweetflag 50
Parts by weight, 30 parts by weight of American Ginseng, 15 parts by weight of fructus alpiniae oxyphyllae, 10 parts by weight of beggar-ticks, 25 parts by weight of Rhizoma Chuanxiong, 15 weight of rhizoma alismatis
Part, 30 parts by weight of pueraria lobata, 10 parts by weight of leech, 15 parts by weight of radix achyranthis bidentatae, 10 parts by weight of the tuber of pinellia, 20 parts by weight of the stem of noble dendrobium, Radix Salviae Miltiorrhizae 20
Parts by weight, 15 parts by weight of Ramulus euonymi, 20 parts by weight of Rhizoma Gastrodiae, 20 parts by weight of Morinda officinalis, 15 parts by weight of the dried immature fruit of citron orange, 35 parts by weight of matrimony vine,
Seven leaf courages, 10 parts by weight, 25 parts by weight of 25 parts by weight of Radix Curcumae, 10 parts by weight of red yeast rice and black fungus.
By above-mentioned raw materials component, preparation method using the present invention prepares Chinese medicine composition：
S101：Each raw material component is weighed in proportion, is crushed to 60 mesh after cleaning, is soaked later.Wherein, the water of addition
Amount is 15 times of raw material components gross mass, soaking time 20min.
S102：Boil the drug use after immersion by intense fire 8min, then exchange of notes fire heats 50min, filters and collects filtrate.
S103：The medicinal extract that relative density is 1.20 when filtrate is condensed into 70 DEG C, obtains Chinese medicine composition.
In addition, the effect of in order to preferably evaluate each embodiment, carry out following experiment：
One, toxicity test
It is the small white mouse 80 (each 40 of male and female) of 18~22g to select weight, is divided into 4 groups, takes implementation of the present invention respectively
The Chinese medicine composition that example one to example IV obtains.Specifically, the Chinese medicine composition 8g for taking the present invention, adds deionized water to be made dense
Contracting liquid 20mL, every small white mouse give concentrate 1.2mL gavages, twice daily；Observation 30 days, small white mouse health existence, nothing
Any toxic side effect；Blood picture, liver function, each organs and tissues state, the indifference compared with normal small white mouse is dissected and observed.Experiment card
Bright, Chinese medicine composition provided by the invention is nontoxic.
Two, clinical test
Collect all kinds of mid-term arteriosclerotics 400, each patient be accompanied by different degrees of palpitaition, pectoralgia, it is uncomfortable in chest,
The symptoms such as the cool fiber crops of headache and dizzy, four limbs.Specifically, patient is divided into 4 groups, every group 100, by first group to the 4th group difference
The embodiment of the present invention one is taken to the Chinese medicine composition 3 weeks of example IV, 2 times a day, each 2g；Curative effect is observed later, and is surveyed
The diminution degree of fixed each patient's artery sclerosis volume, it is specific as shown in table 1.
Curative effect is judged as：
It is effective：The symptoms such as palpitaition, pectoralgia, uncomfortable in chest, headache and dizzy and the cool fiber crops of four limbs disappear；It improves：Palpitaition, pectoralgia, it is uncomfortable in chest,
The symptoms such as headache and dizzy and the cool fiber crops of four limbs are substantially reduced；In vain：The symptoms such as palpitaition, pectoralgia, uncomfortable in chest, headache and dizzy and the cool fiber crops of four limbs
Improve unobvious before and after treatment.Wherein, total effective rate=obvious effective rate+improvement rate.
1 each embodiment patient artery sclerosis symptom situation of change statistical form of table
| Case number of cases/name | Effective/name | Improvement/name | In vain/name | Total effective rate/% | |
| Embodiment one | 100 | 80 | 19 | 1 | 99 |
| Embodiment two | 100 | 83 | 17 | 0 | 100 |
| Embodiment three | 100 | 90 | 10 | 0 | 100 |
| Example IV | 100 | 91 | 9 | 0 | 100 |
Certainly, the case where being enumerated in addition to embodiment one to example IV, the type and weight percent of other raw material components,
Condition and parameter in preparation process etc. are also possible.It should be noted that each patient does not occur not over the course for the treatment of
Suitable symptom.
Chinese medicine composition provided by the invention has excellent qi-regulating promoting circulation of blood, promoting blood circulation and removing blood stasis and softening and resolving hard mass and other effects, energy
Enough significantly improve the symptoms such as palpitaition, pectoralgia, uncomfortable in chest, headache and dizzy and the cool fiber crops of four limbs of arteriosclerotic, and safe and non-toxic pair
Effect；In addition, Chinese medicine composition provided by the invention is easy to use, cost is relatively low, has good commercial promise.
In the description of this specification, it is to be understood that reference term " one embodiment ", " is shown " some embodiments "
The description of example ", " specific example " or " some examples " etc. mean specific features described in conjunction with this embodiment or example, structure,
Material or feature are included at least one embodiment or example of the invention.In the present specification, above-mentioned term is shown
The statement of meaning property is necessarily directed to identical embodiment or example.Moreover, specific features, structure, material or the spy of description
Point may be combined in any suitable manner in any one or more of the embodiments or examples.In addition, without conflicting with each other,
Those skilled in the art can be by different embodiments or examples described in this specification and different embodiments or examples
Feature is combined.
Although the embodiments of the present invention has been shown and described above, it is to be understood that above-described embodiment is example
Property, it is not considered as limiting the invention, those skilled in the art within the scope of the invention can be to above-mentioned
Embodiment is changed, changes, replacing and modification.
Claims (8)
1. a kind of for treating the Chinese medicine composition of artery sclerosis, which is characterized in that raw material components by weight, including：
10~15 parts by weight of Cassia occidentalis, 20~25 parts by weight of SEMEN PINI KORAIENSIS, 20~30 parts by weight of hawthorn, 20~25 parts by weight of giant knotweed,
20~30 parts by weight of Cortex Eucommiae, 30~50 parts by weight of grass-leaved sweetflag, 30~40 parts by weight of American Ginseng, 10~15 parts by weight of fructus alpiniae oxyphyllae, river
15~25 parts by weight of rhizome of chuanxiong, 15~20 parts by weight of rhizoma alismatis, 25~30 parts by weight of pueraria lobata, 10~15 parts by weight of leech, the stem of noble dendrobium 15~20
Parts by weight, 20~30 parts by weight of Radix Salviae Miltiorrhizae, 10~15 parts by weight of Ramulus euonymi, 20~30 parts by weight of Rhizoma Gastrodiae, 15~20 weight of Morinda officinalis
Part, 15~20 parts by weight of the dried immature fruit of citron orange, 25~35 parts by weight of matrimony vine, 15~25 parts by weight of Radix Curcumae, 10~15 parts by weight of red yeast rice and black wood
15~25 parts by weight of ear.
2. the Chinese medicine composition according to claim 1 for treating artery sclerosis, which is characterized in that further include：
10~25 parts by weight of beggar-ticks, 10~15 weight of seven leaf courages, 10~25 parts by weight, 10~15 parts by weight of the tuber of pinellia and radix achyranthis bidentatae
Part.
3. the Chinese medicine composition according to claim 2 for treating artery sclerosis, which is characterized in that by following raw material groups
Divide and is made：
15 parts by weight of Cassia occidentalis, 20 parts by weight of SEMEN PINI KORAIENSIS, 30 parts by weight of hawthorn, 20 parts by weight of giant knotweed, 30 parts by weight of Cortex Eucommiae, stone Chang
30 parts by weight of Pu, 40 parts by weight of American Ginseng, 10 parts by weight of fructus alpiniae oxyphyllae, 25 parts by weight of beggar-ticks, 15 parts by weight of Rhizoma Chuanxiong, 20 weight of rhizoma alismatis
Measure part, 25 parts by weight of pueraria lobata, 15 parts by weight of leech, 10 parts by weight of radix achyranthis bidentatae, 15 parts by weight of the tuber of pinellia, 15 parts by weight of the stem of noble dendrobium, Radix Salviae Miltiorrhizae
30 parts by weight, 10 parts by weight of Ramulus euonymi, 30 parts by weight of Rhizoma Gastrodiae, 15 parts by weight of Morinda officinalis, 20 parts by weight of the dried immature fruit of citron orange, 25 weight of matrimony vine
Part, seven leaf courages, 25 parts by weight, 15 parts by weight of 15 parts by weight of Radix Curcumae, 15 parts by weight of red yeast rice and black fungus.
4. the Chinese medicine composition according to claim 2 for treating artery sclerosis, which is characterized in that by following raw material groups
Divide and is made：
10 parts by weight of Cassia occidentalis, 25 parts by weight of SEMEN PINI KORAIENSIS, 20 parts by weight of hawthorn, 25 parts by weight of giant knotweed, 20 parts by weight of Cortex Eucommiae, stone Chang
50 parts by weight of Pu, 30 parts by weight of American Ginseng, 15 parts by weight of fructus alpiniae oxyphyllae, 10 parts by weight of beggar-ticks, 25 parts by weight of Rhizoma Chuanxiong, 15 weight of rhizoma alismatis
Measure part, 30 parts by weight of pueraria lobata, 10 parts by weight of leech, 15 parts by weight of radix achyranthis bidentatae, 10 parts by weight of the tuber of pinellia, 20 parts by weight of the stem of noble dendrobium, Radix Salviae Miltiorrhizae
20 parts by weight, 15 parts by weight of Ramulus euonymi, 20 parts by weight of Rhizoma Gastrodiae, 20 parts by weight of Morinda officinalis, 15 parts by weight of the dried immature fruit of citron orange, 35 weight of matrimony vine
Part, seven leaf courages, 10 parts by weight, 25 parts by weight of 25 parts by weight of Radix Curcumae, 10 parts by weight of red yeast rice and black fungus.
5. the preparation method of Claims 1 to 4 any one of them Chinese medicine composition, which is characterized in that include the following steps：
S101：Each raw material component is weighed in proportion, is crushed after cleaning, is soaked later；
S102：Boil the drug use after the immersion by intense fire 3~8min, then exchange of notes fire heats 50~80min, filters and receives
Collect filtrate；
S103：The medicinal extract that relative density is 1.10~1.20 when the filtrate is condensed into 70 DEG C, obtains the Chinese medicine composition.
6. the preparation method of the Chinese medicine composition described in claim 5, it is characterised in that：
In the S101, the water of addition is 5~15 times of the raw material components gross mass, soaking time be 20min~
30min。
7. the preparation method of the Chinese medicine composition described in claim 6, it is characterised in that：
In the S101, each raw material component is crushed to 60~100 mesh.
8. Claims 1 to 4 any one of them Chinese medicine composition is preparing treatment atherosclerosis drug and/or medicated premix
In application.
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2018
- 2018-05-16 CN CN201810468276.0A patent/CN108434402A/en active Pending
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|---|---|---|---|---|
| CN1142370A (en) * | 1995-08-07 | 1997-02-12 | 杨旭义 | Capsule for cerebral arteriosclerosis |
| WO2011016366A1 (en) * | 2009-08-05 | 2011-02-10 | 国立大学法人北海道大学 | Cholesterol ester transfer protein inhibitor |
| CN103816454A (en) * | 2014-03-05 | 2014-05-28 | 济南高达信息技术有限公司 | Pure traditional Chinese medicine capsule for treating arteriosclerosis |
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