CN100459997C - Composition of bitter tea and rhubarb horsetails and preparation method thereof - Google Patents

Composition of bitter tea and rhubarb horsetails and preparation method thereof Download PDF

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Publication number
CN100459997C
CN100459997C CNB2004100876426A CN200410087642A CN100459997C CN 100459997 C CN100459997 C CN 100459997C CN B2004100876426 A CNB2004100876426 A CN B2004100876426A CN 200410087642 A CN200410087642 A CN 200410087642A CN 100459997 C CN100459997 C CN 100459997C
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radix
rhizoma rhei
composition
bitter tea
effect
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CN1634425A (en
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王玉生
王晓东
王晓民
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Abstract

The invention provides a composition of bitter tea and rhubarb horsetails and its preparation method for treating herpes zoster virus, which comprises bitter tea 20-30, rhubarb horsetails 60-90, the bitter tea and the rhubarb horsetails are ground into powder medicine, the composition has no toxic and side actions, but has the advantages of short course of treatment, quick action, appreciable action, no recrudesce tendency, low cost and easiness in administration.

Description

The purposes of Folium Ligustri pubescentis and Radix Et Rhizoma Rhei compositions
Affiliated field
The present invention relates to Chinese herbal and crude drugs preparations, particularly Folium Ligustri pubescentis and Radix Et Rhizoma Rhei composition and method of making the same.With the combination of the combination of Folium Ligustri pubescentis and Radix Et Rhizoma Rhei or its extract, be to utilize both complementary functions, what treatment virus caused sends out in waist " herpes zoster " herpes zoster, and both vesicles in groups is zonal distribution along peripheral nerve, and Chinese medicine claims " herpes zoster ".Can play sterilization, antibiotic, suppress and therapeutical effect.
Background technology
Traditional Chinese herbal medicine is medical to be single less, mostly being compound recipe, being particular about monarch, is the main treatment disease with one, two flavor monarchs drug often, but because Chinese herbal medicine composition complexity, except that active ingredient, also have a large amount of impurity, even harmful material, have side effects, so that poison, need other ministerial drug assistants to make and eliminate the effects of the act, help to absorb, thereby the prescription volume is excessive, unfavorable use, also existence disappears, and this answers that toxic and side effects, and cancels out each other, reduce drug effect, be difficult to bring into play the real effect of principal agent, particularly absorption is slow, drug effect is low, demands urgently improving.
Folium Ligustri pubescentis: for tender shoots, the leaf of plant of theaceae tea, be with green shrub or dungarunga.Originate in the Yangtze river basin and on the south various places.Chemical constituent: Folium Camelliae sinensis purine-containing Alkaloid, based on caffeine.Content is about 1%-5%, and contains Theobromine, theophylline and the xanthine of trace, also contains tannin, based on Galla Turcica (Galla Helepensis) acyl-left-handed-epigallocatechin, and contains a small amount of left-handed gallo catechin.The Galla Turcica (Galla Helepensis) epicatechin.Caffeine major part in Folium Camelliae sinensis combines with tannin and exists.The commercially available Folium Camelliae sinensis that China produced generally contains caffeine 2%-4%, contains tannin about 5%-15%, containing performance oil 0.6% again is the fragrance component of Folium Camelliae sinensis, main component is β, and the r-vinyl alcohol accounts for 50%-90%, and contain the a-hexenal, linalool and oxide thereof, Mang geraniol etc., other contains triterpene saponin and aglycon thereof, theasapogenol, tea saponin etc.Also contain 130-180 milligrams of % of vitamin C, a small amount of carotene, dihydroergosterol, some fat that Quercetin, nimbecetin etc. and flavonol and gallic acid are formed; Pharmacological action: theophylline and caffeine contained in the Folium Camelliae sinensis have powerful excitation to the central nervous system, the excited cerebral cortex of low dose of energy, and sleepiness reduces, and fatigue alleviates, and thinking is more clear, quick; Heart there is excitation, but proarrhythmia during high concentration; Prevention and the effect of treatment hypercholesterolemia are arranged; Tangible blood pressure lowering and arteriosclerosis effect are arranged; Has fibrinolysis enhancing, anticoagulant and inhibition thrombosis; Folium Camelliae sinensis still has anti-aging effects; Tangible diuresis is arranged; Antiasthmatic effect is arranged, strengthen people's skeletal muscle mobility; The antiinflammatory anti-allergic effects is arranged; Folium Camelliae sinensis and effective ingredient have certain antitumaous effect, outside its anticancer machine-processed decapacitation direct killing cancerous cell, may with the generation that suppresses nitroso compound, antimutagenic, the effects such as oxygen radical and enhancing human body immunity function of removing are relevant; Folium Camelliae sinensis extract caffeine and tannin, to cowpox, herpes simplex etc. have inhibitory action in various degree.The property of medicine: bitter in the mouth, sweet, cool in nature.GUIXIN, lung, stomach, kidney channel.Function: the refresh oneself, put forward spirit, relieving thirst and restlessness helps digestion, and reduces phlegm diuresis, detoxifcation.Usage and dosage: soup 1-10 grams of frying in shallow oil for oral administration, make tea or go into ball and loose; External: an amount of.
Radix Et Rhizoma Rhei: different name general commonly used, Radix Et Rhizoma Rhei, yellow good, another name for Sichuan Province Radix Et Rhizoma Rhei, bright and beautiful civilian Radix Et Rhizoma Rhei.Be polygonum rheum palmatum, the root footpath and the root of Rheum tanguticum and Rheum officinale.Sorrel: perennial tall and big draft, the sturdy plumpness of rhizome.Stem is upright, and hollow is up to about 2 meters.Be born in mountain region border or grass slope, wild or cultivation; Rheum tanguticum: have another name called rheum tanguticum Tschircs, Beijing University's Huang, this kind and sorrel fairly similar, the main distinction is: blade drastic crack, sliver often are triangular shape lanceolar or narrow linear, and spray is tight, and be upwards upright, is close to stem.Be born in the more dark and damp place of mountain region border; Rheum officinale: have another name called RADIX ET RHIZOMA RHEI OFFICILALIS, todaiwo,rhizoma, refined Huang, this kind and last two kinds of main distinctions: basal leaf and shallow splitting, sliver are big profile of tooth or wide triangle; Ochrea is membranous, and is more transparent, on undercoat is arranged; Flower is bigger, pistac, and Fruit branch is carried out, and the Myriopteron extensum (Wight) K. Schum edge is opaque.Be born in mountain region border or grass slope.Chemical constituent: Radix Et Rhizoma Rhei contains anthraquinone derivative, tannin and organic acid etc., and dissociated anthraquinone has: chrysophanic acid, aloe-emodin, emodin, physcione, chrysophanol.Combined anthraquinone has: physcione-8-glucoside, aloe-emodin-8-glucoside, chrysophanol-1-glucoside etc.; The dianthracene ketones component has: sorrel dianthrone, A, B, C, D etc.Also resinous, epicatechin, epicatechol gallate, galloyl glucose etc.Pharmacological action: Radix Et Rhizoma Rhei has the effect of dropping, and this effect is decocted the influence of temperature and time, and Radix Et Rhizoma Rhei prolongs heat time heating time, and the effect of then dropping weakens, and is advisable in 30-60 minutes so decoct.The composition that drops of Radix Et Rhizoma Rhei is a sennoside; Radix Et Rhizoma Rhei can promote bile secretion, and bilirubin and bile acid content are increased; Radix Et Rhizoma Rhei has effects such as antibacterium, fungus, virus, the has a broad antifungal spectrum of Radix Et Rhizoma Rhei, and with chrysophanic acid, the antibacterial action of emodin and aloe-emodin is the strongest in the antibacterial effective ingredient; Radix Et Rhizoma Rhei has obvious inhibitory action to multiple zoopery inflammation; Various zooperies show that Radix Et Rhizoma Rhei has anastalsis, can obviously shorten hemorrhage and clotting time, and its hemostasis effective ingredient is a chrysophanol, physcione, a-cachou extract and gallic acid; Chrysophanic acid and Radix Et Rhizoma Rhei have antitumor action, and its mechanism of action mainly is the oxidation and the dehydrogenation of anticancer; Zoopery shows that Radix Et Rhizoma Rhei also has effects such as the blood fat reducing diuresis protects the liver.The property of medicine: bitter in the mouth, cold in nature.Return stomach, large intestine, liver, spleen channel.Function: stasis removing, eliminating fire and detoxication, blue heat dampness removing, cooling blood for hemostasis.Clinical practice: be used for the solid cubic content constipation, distension and fullness in the abdomen; Be used for damp and hot stagnant dysentery, tenesmus; Be used for jaundice due to damp-heat, gonorrhea, edema; Be used for scorching all diseases on the pathogenic fire, as headache, conjunctival congestion and swelling pain is had sore throat, gingivitis, and aphtha of the mouth and tongue with constipation due to dry stool; Be used for the pyretic toxicity carbuncle, erysipelas, skin infection is scalded etc.In addition, existing Radix Et Rhizoma Rhei also is usually used in treating chronic renal insufficiency and uremia.How single oral with Radix Et Rhizoma Rhei powder.Usage and dosage: for oral administration, fry in shallow oil soup 3-12 gram, grind the 0.5-2 gram into powder, or the bubble drink.External: an amount of.
Summary of the invention
The present invention is directed to the prior art deficiency, utilize modern biochemical technology and Chinese medicine and pharmacy theory, a kind of Folium Ligustri pubescentis and Radix Et Rhizoma Rhei composition and method of making the same are provided, Chinese herbal medicine Folium Ligustri pubescentis and Radix Et Rhizoma Rhei are ground the synthetic powder in back, utilize the complementary effect of this two flavor Chinese herbal medicine, what treatment virus caused sends out in waist " herpes zoster " herpes zoster.Can play sterilization, antibiotic, suppress and therapeutical effect.
Folium Ligustri pubescentis and Radix Et Rhizoma Rhei compositions, Folium Ligustri pubescentis 20-30, Radix Et Rhizoma Rhei 60-90.
Folium Ligustri pubescentis can be the extract alkaloid, and based on caffeine, content is about 1%-5%, and contains Theobromine, theophylline and the xanthine of trace, also contains tannin, based on Galla Turcica (Galla Helepensis) acyl-left-handed-epigallocatechin, and contains a small amount of left-handed gallo catechin; Other contains triterpene saponin and aglycon thereof, theasapogenol, tea saponin; Radix Et Rhizoma Rhei can be the extract anthraquinone derivative, tannin and organic acid etc., and dissociated anthraquinone has: chrysophanic acid, aloe-emodin, emodin, physcione, chrysophanol; Combined anthraquinone has: physcione-8-glucoside, aloe-emodin-8-glucoside, chrysophanol-1-glucoside etc.; The dianthracene ketones component has: sorrel dianthrone, A, B, C, D etc., also resinous, epicatechin, epicatechol gallate, galloyl glucose.
Folium Ligustri pubescentis and Radix Et Rhizoma Rhei preparation method of composition, Folium Ligustri pubescentis and Radix Et Rhizoma Rhei grind the synthetic powder in back.
Folium Ligustri pubescentis and Radix Et Rhizoma Rhei compositions, be different from existing Chinese herbal compound preparation, reaching test by experiment confirms: these product have no side effect, short treating period, instant effect, effect obviously, do not recur, economical and convenient, herpes zoster oral medicine that more present clinical treatment virus causes and external method have the difference of essence, fundamentally remove slight illness, have utilized the effect and the Folium Ligustri pubescentis extract of Radix Et Rhizoma Rhei extract chrysophanic acid, emodin and aloe-emodin: the effect of caffeine and tannin, can sterilization, antibiotic, inhibition and treatment varicella zoster virus.Treat tens of people, obvious effective rate 25%, cure rate 75%, effective percentage 100%.This technology has overcome present treatment varicella zoster virus application limitations and deficiency, has opened new gate for its extensive use, is suitable for penetration and promotion.
Usage: after 15 minutes the external application affected part with the strong tea blister for this product, recovery from illness in 2-5 days.
The specific embodiment:
Embodiment 1
Folium Ligustri pubescentis and Radix Et Rhizoma Rhei compositions, Folium Ligustri pubescentis 10 grams, Radix Et Rhizoma Rhei 30 grams.After 15 minutes the external application affected part with the strong tea blister for this product, recovery from illness in 2-5 days.
Embodiment 2
Folium Ligustri pubescentis and Radix Et Rhizoma Rhei compositions, Folium Ligustri pubescentis 12 grams, Radix Et Rhizoma Rhei 30 grams.After 15 minutes the external application affected part with the strong tea blister for this product, recovery from illness in 2-5 days.
Embodiment 3
Folium Ligustri pubescentis and Radix Et Rhizoma Rhei preparation method of composition, Folium Ligustri pubescentis 10 grams grind the synthetic powder in back with Radix Et Rhizoma Rhei 30 grams, and fineness of grind is 50 orders.
Embodiment 4
Folium Ligustri pubescentis and Radix Et Rhizoma Rhei compositions can add various medicines according to various objectives, as the carrier of multiple formulations.
Embodiment 5 (typical case history):
King X man 60 years old was a virus infected herpes at hospital diagnosis once, and was all invalid with medicines such as general and quick, diphenhydramine, cortisone ointment, moroxydine, SHUANGHUANGLIAN JIAONANG, vitamin B1, B2, and after 15 minutes the external application affected part with the strong tea blister for back this product, recovery from illness in 2 days.
Korea Spro XX woman 62 years old, hospital diagnosis is viral herpes zoster, the doctor requires to have an intravenous drip; take medicine, expense needs 1000-1500 yuan approximately, because of the economic situation reason; the old man only requires make war for oral administration, medicine for external use, and SHUANGHUANLIAN, vitamin B1, B2, detoxicating tablet of cow-bezoar, Povidone-Iodine Solution liquid are wherein arranged.The state of an illness is not effectively controlled after patient's medication, state of an illness aggravation, and the site of disease area increases, and the pain increased.After 15 minutes the external application affected part with the strong tea blister for back this product, recovery from illness after 5 days, and the old man is very happy.
The curative effect summary, after 15 minutes the external application affected part with the strong tea blister for this product at short notice, fully recovers after 2-5 days, and easy to use, curative effect is obvious, rapidly, does not recur.

Claims (1)

1. Folium Ligustri pubescentis and Radix Et Rhizoma Rhei compositions are used to prepare the purposes of the medicine for the treatment of herpes zoster, it is characterized in that: Folium Ligustri pubescentis 20-30, Radix Et Rhizoma Rhei 60-90.
CNB2004100876426A 2004-11-23 2004-11-23 Composition of bitter tea and rhubarb horsetails and preparation method thereof Expired - Fee Related CN100459997C (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1961698B (en) * 2006-11-21 2010-06-23 张�林 An improved tea leaf
CN105769842A (en) * 2016-05-25 2016-07-20 江苏康缘药业股份有限公司 Rheidin application and antiviral drugs

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1327829A (en) * 2001-06-07 2001-12-26 黄宝生 Tea leaf-seed ointment for treating scald and its preparing process
CN1390554A (en) * 2001-06-09 2003-01-15 汤仪 Inflammation relieving paste

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1327829A (en) * 2001-06-07 2001-12-26 黄宝生 Tea leaf-seed ointment for treating scald and its preparing process
CN1390554A (en) * 2001-06-09 2003-01-15 汤仪 Inflammation relieving paste

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
生大黄在皮肤科的应用. 王莉,孙晓萍.中国新医药杂志,第2卷第6期. 2003
生大黄在皮肤科的应用. 王莉,孙晓萍.中国新医药杂志,第2卷第6期. 2003 *

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