CN108432885A - A kind of composition containing hippophae rhamnoides fruit oil - Google Patents
A kind of composition containing hippophae rhamnoides fruit oil Download PDFInfo
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- CN108432885A CN108432885A CN201810069232.0A CN201810069232A CN108432885A CN 108432885 A CN108432885 A CN 108432885A CN 201810069232 A CN201810069232 A CN 201810069232A CN 108432885 A CN108432885 A CN 108432885A
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- oil
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- raspberry
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- hippophae rhamnoides
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
- A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
- A23D9/007—Other edible oils or fats, e.g. shortenings, cooking oils characterised by ingredients other than fatty acid triglycerides
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- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention provides a kind of raspberry, sea-buckthorn, matrimony vine, white thorn composite fruit fluid composition, raw material is made of the component of weight proportion：10~30 parts of raspberry fruit oil, 12~25 parts of hippophae rhamnoides fruit oil, 14~25 parts of fructus lycii oil, 13~35 parts of white bur oil.The present invention organically combines raspberry fruit oil, hippophae rhamnoides fruit oil, fructus lycii oil, white bur oil, and antioxidant activity is substantially better than the individual antioxidant activity of four seed oils under same concentration.Above-mentioned experiment conclusion suffices to show that, raspberry provided by the invention, sea-buckthorn, oil of Nitraria seeds composition have the function of synergy.
Description
Technical field
The invention belongs to field of health care products, and in particular to a kind of raspberry, sea-buckthorn, matrimony vine, white thorn composite fruit fluid composition.
Technical background
Unsaturated fatty acid is the indispensable aliphatic acid of human body, is divided into monounsaturated fatty acid according to the difference of double bond number
Acid and polyunsaturated fatty acid.Monounsaturated fatty acids has oleic acid, palmitoleic acid, ricinoleic acid etc..Polyunsaturated fatty acid has
Linoleic acid, leukotrienes, arachidonic acid etc..Some unsaturated fatty acid human bodies cannot synthesize itself, it is necessary to it is supplemented from diet,
Such as linoleic acid plus linolenic acid.Unsaturated fatty acid content is higher in many vegetable oil, such as olive oil, Ah's glycerine, soybean oil, jade
Rice bran oil, sunflower fruit oil etc..Unsaturated fatty acid has very important physiological action, including keeps the mobility of cell membrane, dimension
Hold cell normal physiological function；Blood fat is adjusted, cholesterol and triglycerides in blood are reduced, this is to preventing cardiovascular and cerebrovascular disease
Play key effect；Immunoloregulation function；It is the precursor substance of prostaglandin and thromboxane in synthesized human；It improves
Brain cell activity, enhancing memory etc..
With the continuous improvement of people's health care consciousness, raspberry fruit oil, hippophae rhamnoides fruit oil, fructus lycii oil, white bur oil etc. are with small
Berry seed is that the novel dietotherapy health-care oil of raw material increasingly receives an acclaim.The study found that the slurries such as raspberry, sea-buckthorn, matrimony vine, white thorn
Containing a large amount of abundant unsaturated fatty acids in the seed pod oil of fruit, there is high nutritive value and health value.White bur oil
In contain a large amount of unsaturated fatty acid, while also contain inoxidizability tocopherol and sterols.Hippophae rhamnoides fruit oil is by palmitic acid, palm fibre
The multiple beneficials aliphatic acid such as palmitic acid olefin(e) acid, stearic acid, oleic acid, linoleic acid, leukotrienes forms, and wherein unsaturated fatty acid is up to
70%, unsaturated acids type and content is all quite high in all vegetable oil.There are a large amount of vitamin E, dimension in hippophae rhamnoides fruit oil
Raw element A, carotenoid, the mineral elements such as various trace elements and selenium, magnesium, zinc, iron, manganese.In addition, also containing in hippophae rhamnoides fruit oil
There are a small amount of phytosterol, catechin and flavone compound.The indispensable substance of these activities that sustain life so that husky
Spine fruit oil becomes the comprehensive novel dietotherapy health-care oil of nutrition, and health value is high.Contain up to 95% or more in raspberry fruit oil
Unsaturated fatty acid, wherein oleic acid account for 17%, and linoleic acid accounts for 49%, and alpha-linolenic acid accounts for 33%.Meanwhile also containing in raspberry fruit oil
Very a high proportion of vitamin E and vitamin A have very strong free radical scavenging ability, are rare new type health plants
Oil.Contain abundant unsaturated fatty acid and a large amount of vitamin Es in fructus lycii oil, there is significant reducing blood lipid, hypoglycemic, anti-dynamic
The effects that pulse atherosclerosis, anticancer, supplement brain nutrition, antifatigue, beautifying face and moistering lotion.
In recent years, small berries industry development is rapid, breaks berry tradition edible way, carries out intensive processing, starches realizing
The higher value application of fruit has very important significance.It yet there are no raspberry fruit oil, hippophae rhamnoides fruit oil, fructus lycii oil, white thorn
The report that fruit oil is used in combination.
Invention content
The combination based on raspberry fruit oil, hippophae rhamnoides fruit oil, fructus lycii oil, white bur oil that the purpose of the present invention is to provide a kind of
Object.
Specifically, the present invention provides a kind of raspberry, sea-buckthorn, matrimony vine, white thorn composite fruit fluid composition, raw material is by weight
The component of proportioning forms：
10~30 parts of raspberry fruit oil, 12~25 parts of hippophae rhamnoides fruit oil, 14~25 parts of fructus lycii oil, 13~35 parts of white bur oil.
Further, raw material is made of the component of weight proportion：
15~25 parts of raspberry fruit oil, 15~25 parts of hippophae rhamnoides fruit oil, 15~25 parts of fructus lycii oil, 15~25 parts of white bur oil.
Preferably, raspberry fruit oil:Hippophae rhamnoides fruit oil:Fructus lycii oil:White bur oil=1:1:1:1.
Wherein, the composition is using the raw material of the proportioning as active constituent, in addition on food, health products or drug often
The preparation that auxiliary material or complementary ingredient are prepared.In actual use, it can be prepared different according to the market demand
Dosage form, such as through gastrointestinal tract absorption type.
The present invention also provides above-mentioned compositions to prepare the use in having the food, health products or drug of anti-oxidation efficacy
On the way.
Further, the food, health products or drug be scavenging hydroxyl, ultra-oxygen anion free radical or ABTS from
By the food, health products or drug of base.
The present invention organically combines raspberry fruit oil, hippophae rhamnoides fruit oil, fructus lycii oil, white bur oil, antioxidant activity
It is substantially better than the individual antioxidant activity of four seed oils under same concentration.Above-mentioned experiment conclusion suffices to show that, provided by the invention
Raspberry, sea-buckthorn, oil of Nitraria seeds composition have the function of synergy.
Description of the drawings
Scavenging activity of Fig. 1 tetra- seed pods oil objects in combination to ABTS
Scavenging activity of Fig. 2 tetra- seed pods oil objects in combination to hydroxy radical
Fig. 3 tetra- seed pods oil object in combination is to ultra-oxygen anion free radical Scavenging activity
Specific implementation mode
Fruit oil, is produced using known fruit oil preparation method using each berry after remove seed as raw material alleged by the present invention,
Such as squeeze or extract, conventional extraction includes carbon dioxide supercritical extraction technology.
Embodiment 1
Table 1
| Ingredient | 1 (g) of group | 2 (g) of group | 3 (g) of group |
| Raspberry fruit oil | 15 | 15 | 25 |
| Hippophae rhamnoides fruit oil | 15 | 25 | 15 |
| Fructus lycii oil | 15 | 25 | 15 |
| White bur oil | 15 | 25 | 15 |
According to the proportioning in table 1, by each component mixing to get the present composition.It is, of course, also possible to according to practical need
It asks, composition is prepared into corresponding preparations.
Antioxidation activity in vitro is tested
(1) material：Raspberry fruit oil, hippophae rhamnoides fruit oil, fructus lycii oil, white bur oil and four are with 1:1:1:The fruit of 1w/w mixing
Fluid composition.
(2) laboratory apparatus and reagent：Tube centrifuge (TGL-16G-A types, Anting Scientific Instrument Factory, Shanghai)；It can be seen that ultraviolet
Spectrophotometer (UV-722N, Shanghai Ni Ke Co., Ltds)；Thermostat water bath (HD types, Constant Temp. Instrument Factory, Liaoyang).ABTS is purchased
In Shanghai Jing Chun biochemical technologies limited liability company (Aladdin)；Potassium peroxydisulfate, sodium dihydrogen phosphate, disodium hydrogen phosphate, sodium chloride,
The reagents such as trichloroacetic acid are purchased from Shandong YuWang Industry Co., Ltd；Superoxide anion kit, hydroxy radical kit are purchased
Bio tech ltd is built up in Nanjing.
(3) ABTS Scavenging activities：ABTS is dissolved into (+H2O) to final concentration of 7mmol/L, potassium peroxydisulfate is configured to
2.45mmol/L mixes the two solution, is positioned over dark, stirs 16h under room temperature；Then ABTS mixed solutions are used
It is 0.70 ± 0.02 that PBS solution (PH=7.0), which is diluted to its light absorption value (being surveyed at 734nm),；Raspberry, matrimony vine, pierces four at sea-buckthorn in vain
Seed pod oil and four seed pod fluid compositions are diluted to various concentration (0.5mg/mL, 1mg/mL, 2mg/mL, 4mg/ with distilled water respectively
ML, 8mg/mL and 16mg/mL)；Finally the sample of above-mentioned various concentration is added in ABTS mixed solutions, sample and ABTS
Mixed solution ratio is 1:20,6min is incubated after mixing at room temperature, light absorption value is measured at 734nm.It is calculated according to formula
Clearance rate.ABTS clearance rates (%)=(1- samples light absorption value/blank absorbency) × 100%.The result is shown in Figure 1.
(4) Hydroxyl radical-scavenging ability：Hydroxy radical is generated using Fenton reaction principles, is sent with sarranine developing dye
Measure the Scavenging activity to hydroxy radical.Raspberry, sea-buckthorn, matrimony vine, four seed pods of white thorn oil and four seed pod fluid compositions are used respectively
Distilled water is diluted to various concentration (1mg/mL, 2mg/mL, 4mg/mL, 8mg/mL, 16mg/mL).Each group sequentially adds
Tris-HCl buffer solutions (pH7.4) 1ml, 0.04mg/ml sarranine solution 1ml, distilled water 1ml, 0.945mmol/ of 0.15mol/L
The EDTANa-Fe of L2+Solution (pH7.4) 0.5ml, sample 0.5ml and 1%H2O2Solution 0.5ml is incubated 30min in 37 DEG C, right
It is replaced with distilled water according to group, blank group EDTANa-Fe2+Solution and sample are replaced with distilled water.Light absorption value is detected at 520nm.
Clearance rate is calculated according to formula.Scavenging action to hydroxyl free radical (%)=1- samples light absorption value/blank absorbency × 100%.As a result
See Fig. 2.
(5) ultra-oxygen anion free radical Scavenging activity：It is free that superoxide anion is generated using xanthine/xanthine oxidase
Scavenging activity of the base system of determination to superoxide radical.By raspberry, sea-buckthorn, matrimony vine, four seed pods of white thorn oil and the combination of four seed pod oil
Object is diluted to various concentration (1mg/mL, 2mg/mL, 4mg/mL, 8mg/mL, 16mg/mL) with distilled water respectively.Each group adds successively
Enter 75mmol/L phosphate buffers (pH7.8) 1ml, sample 0.2ml (control group is replaced with distilled water), 0.1mol/L hydrochloric acid hydroxyls
Amine aqueous solution 0.1ml, 75mmol/L xanthine solution 0.1ml and 0.037U/ml xanthine oxidase solution 0.1ml is uniformly mixed
27 DEG C of incubation 30min afterwards.2ml color developing agents (0.4g/L alpha naphthylamine+4g/L p-aminobenzene sulfonic acid) are added, are stood after mixing
Light absorption value on the downside of 5min, 530nm.Clearance rate is calculated according to formula.Ultra-oxygen anion free radical clearance rate (%)=1- samples
Light absorption value/blank absorbency × 100%.As a result see Fig. 3.
Claims (7)
1. a kind of raspberry, sea-buckthorn, matrimony vine, white thorn composite fruit fluid composition, it is characterised in that：Its raw material by weight proportion component
Composition：
10~30 parts of raspberry fruit oil, 12~25 parts of hippophae rhamnoides fruit oil, 14~25 parts of fructus lycii oil, 13~35 parts of white bur oil.
2. raspberry according to claim 1, sea-buckthorn, matrimony vine, white thorn composite fruit fluid composition, it is characterised in that：Its raw material
It is made of the component of weight proportion：
15~25 parts of raspberry fruit oil, 15~25 parts of hippophae rhamnoides fruit oil, 15~25 parts of fructus lycii oil, 15~25 parts of white bur oil.
3. composite fruit fluid composition according to claim 1, it is characterised in that：Raspberry fruit oil:Hippophae rhamnoides fruit oil:Fructus lycii
Oil:
White bur oil=1:1:1:1.
4. composite fruit fluid composition according to claim 1, it is characterised in that：The composition is with the original of the proportioning
Material is active constituent, in addition the preparation that common auxiliary material or complementary ingredient are prepared on food, health products or drug.
5. composite fruit fluid composition according to claim 4, it is characterised in that：The preparation is through gastrointestinal tract absorbent
Type.
6. composition described in Claims 1 to 5 is preparing the purposes in having the food, health products or drug of anti-oxidation efficacy.
7. purposes according to claim 6, it is characterised in that：The food, health products or drug be scavenging hydroxyl,
The food of ultra-oxygen anion free radical or ABTS free radicals, health products or drug.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810069232.0A CN108432885A (en) | 2018-01-24 | 2018-01-24 | A kind of composition containing hippophae rhamnoides fruit oil |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810069232.0A CN108432885A (en) | 2018-01-24 | 2018-01-24 | A kind of composition containing hippophae rhamnoides fruit oil |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108432885A true CN108432885A (en) | 2018-08-24 |
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ID=63191161
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| CN201810069232.0A Pending CN108432885A (en) | 2018-01-24 | 2018-01-24 | A kind of composition containing hippophae rhamnoides fruit oil |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104306554A (en) * | 2014-09-29 | 2015-01-28 | 中国科学院西北高原生物研究所 | Food, health product or medicine composition for treating gastric ulcer |
| CN104857105A (en) * | 2015-04-04 | 2015-08-26 | 青海瑶池生物科技有限公司 | Soft capsule based on raspberry fruit oil and application and preparation method thereof |
| CN104862069A (en) * | 2015-04-04 | 2015-08-26 | 青海瑶池生物科技有限公司 | Raspberry fruit oil and application thereof |
| CN106148134A (en) * | 2016-08-31 | 2016-11-23 | 青海清华博众生物技术有限公司 | A kind of immersion fruit wine and preparation method thereof |
| CN107149629A (en) * | 2017-05-15 | 2017-09-12 | 中国科学院西北高原生物研究所 | A kind of matrimony vine fat capsule with anti-oxidation efficacy and preparation method thereof |
-
2018
- 2018-01-24 CN CN201810069232.0A patent/CN108432885A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104306554A (en) * | 2014-09-29 | 2015-01-28 | 中国科学院西北高原生物研究所 | Food, health product or medicine composition for treating gastric ulcer |
| CN104857105A (en) * | 2015-04-04 | 2015-08-26 | 青海瑶池生物科技有限公司 | Soft capsule based on raspberry fruit oil and application and preparation method thereof |
| CN104862069A (en) * | 2015-04-04 | 2015-08-26 | 青海瑶池生物科技有限公司 | Raspberry fruit oil and application thereof |
| CN106148134A (en) * | 2016-08-31 | 2016-11-23 | 青海清华博众生物技术有限公司 | A kind of immersion fruit wine and preparation method thereof |
| CN107149629A (en) * | 2017-05-15 | 2017-09-12 | 中国科学院西北高原生物研究所 | A kind of matrimony vine fat capsule with anti-oxidation efficacy and preparation method thereof |
Non-Patent Citations (4)
| Title |
|---|
| 宁盛 等: "《树莓栽培与贮藏加工新技术》", 30 June 2005, 中国农业出版社 * |
| 管华诗 等: "《中华海洋本草 第2卷 海洋矿物药与海洋植物药》", 30 September 2009, 上海科学技术出版社 * |
| 蒋兴民: "《宁夏枸杞》", 30 September 2003, 宁夏人民出版社 * |
| 赵春建 等: "《沙棘生物活性物质综合利用》", 31 July 2013, 黑龙江科学技术出版社 * |
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Application publication date: 20180824 |
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