CN108428613A - Open type ion source and method - Google Patents
Open type ion source and method Download PDFInfo
- Publication number
- CN108428613A CN108428613A CN201711494194.5A CN201711494194A CN108428613A CN 108428613 A CN108428613 A CN 108428613A CN 201711494194 A CN201711494194 A CN 201711494194A CN 108428613 A CN108428613 A CN 108428613A
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- China
- Prior art keywords
- connector
- pipe
- open type
- ion source
- type ion
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Classifications
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/06—Electron- or ion-optical arrangements
- H01J49/062—Ion guides
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/10—Ion sources; Ion guns
- H01J49/107—Arrangements for using several ion sources
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/10—Ion sources; Ion guns
- H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
- H01J49/165—Electrospray ionisation
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- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Plasma & Fusion (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Abstract
The present invention provides a kind of open type ion source and method, ion source includes medium tube, high-field electrode and grounding electrode；First connector, conductive contact, the second connector and connector are sequentially connected；There is first passage and second channel, the angle between the axis of second channel and the axis of first passage is acute angle or right angle in connector；Medium tube is arranged in the exit of connector；First pipe is arranged in the first connector, and one end extends in conductive contact；Second pipe is arranged in the second connector, and one end extends in conductive contact, and the other end extends in first passage；The distance between end of first pipe and second pipe is more than zero；In second pipe on the flow direction of fluid, the end of the second pipe in first passage is located at the downstream of the junction of first passage and second channel；Third connector connects connector；Third pipeline is arranged in third connector, and one end extends in second channel.The present invention has many advantages, such as applied widely.
Description
Technical field
The present invention relates to illicit drugs inspection analyses, more particularly to open type ion source and method.
Background technology
Open type mass ion source is a kind of device that sample ionization can be realized under open type environment, relies on sample
Dosage is few, analyze speed is fast, supports the advantages that real-time in-situ detection, becomes the forward position focus of present mass-spectrometric technique research.At present
Have been developed that a variety of different open type mass ion sources, such as DESI, DART, DBDI, EESI.
Such analytical technology mainly has following deficiency：Wide spectrum poor universality, analysis do not have to material demand and use different ions
Source can not analyze the affine energy micromolecular compound of proton if DART is suitble to analyze organic micromolecule compound, and DESI is suitble to analyze
Polarity macromolecular compound can not analyze the organic micromolecule compound of low pole.
Invention content
For the deficiency for solving in above-mentioned prior art, the present invention provides a kind of open type ions applied widely
Source.
The purpose of the present invention is what is be achieved through the following technical solutions：
A kind of open type ion source, the open type ion source include medium tube, high-field electrode and grounding electrode；It is described spacious
Open type ion source further comprises：
First connector；
Conductive contact；
Second connector；
Connector, first connector, conductive contact, the second connector and connector are sequentially connected；Tool in the connector
It is acute angle or right angle to have first passage and second channel, the angle between the axis of second channel and the axis of first passage；It is described
Medium tube is arranged in the exit of the connector；
First pipe, the first pipe is arranged in first connector, and one end extends in the conductive contact；
Second pipe, the second pipe is arranged in second connector, and one end extends in the conductive contact,
The other end extends in the first passage；Between first pipe and the end of second pipe in the conductive contact
Distance is more than zero；In the second pipe on the flow direction of fluid, the end of the second pipe in the first passage
Portion is located at the downstream of the junction of the first passage and second channel；
Third connector, the third connector connect the connector；
Third pipeline, the third pipeline is arranged in the third connector, and one end extends in the second channel.
The present invention also aims to provide a kind of work side applied widely according to above-mentioned open type ion source
Method, the goal of the invention are achieved by the following technical programs：
According to the working method of above-mentioned open type ion source, the working method is：
Apply DC voltage to the conductive contact, electric field is formed between the conductive contact and grounding electrode；To institute
It states high-field electrode and applies alternating voltage；
Testing liquid is entered by first pipe in second pipe, and is sprayed out of described second pipe, in the electricity
Under field action, spraying is formed；
Gas enters from third pipeline in the second channel and first passage, and shape in the region of discharge in medium tube
At plasma, to ionize the sample in the misty testing liquid into the medium tube.
Compared with prior art, the device have the advantages that being：
It is applied widely, not only can be by plasma ionization low pole compound, but also it can be by electron spray ion
Change macromolecular compound.
Description of the drawings
With reference to attached drawing, the disclosure will be easier to understand.Skilled addressee readily understands that be：This
A little attached drawings are used only for the technical solution illustrated the present invention, and are not intended to and are construed as limiting to protection scope of the present invention.
In figure：
Fig. 1 is the structure diagram of according to embodiments of the present invention 1 open type ion source.
Specific implementation mode
Fig. 1 and following description describe the present invention optional embodiment with instruct those skilled in the art how to implement and
Reproduce the present invention.In order to instruct technical solution of the present invention, some conventional aspects are simplified or have been omitted.Those skilled in the art answer
The understanding is originated from the modification of these embodiments or replacement will within the scope of the invention.Under those skilled in the art should understand that
Stating feature can combine in various ways to form multiple modifications of the present invention.The invention is not limited in following optional as a result,
Embodiment, and be only limited by the claims and their equivalents.
Embodiment 1：
Fig. 1 schematically illustrates the structure diagram of the open type ion source of the embodiment of the present invention, as shown in Figure 1, described
Open type ion source includes：
First connector 2, first connector have external screw thread；
Conductive contact 3 such as uses metal material, one end of the conductive contact to have the external screw thread with first connector
Matched internal thread, the other end have the matched internal thread of external screw thread with one end of the second connector；
Second connector 5, the both ends of second connector have an external screw thread, the external screw thread of the other end of the second connector with it is described
The internal thread of connector matches；
Connector 6, first connector, conductive contact, the second connector and connector are sequentially connected；Tool in the connector
It is acute angle or right angle to have first passage 12 and second channel 13, the angle between the axis of second channel and the axis of first passage；
Medium tube 7, the medium tube are arranged in the exit of the connector；
First pipe 1, the first pipe is arranged in first connector, and one end extends to the conductive contact
It is interior；
Second pipe 4, such as capillary glass tube or stainless steel capillary, the second pipe is arranged in second connector
It is interior, and one end extends in the conductive contact, the other end extends in the first passage；In the conductive contact
The distance between end of first pipe and second pipe is more than zero；In the second pipe on the flow direction of fluid, place
It is located at the downstream of the junction of the first passage and second channel in the end of the second pipe in the first passage；
Third connector 10, the third connector connect the connector；
Third pipeline 11, the third pipeline is arranged in the third connector, and one end extends to the second channel
It is interior；
High-field electrode 8 and grounding electrode 9, if high-field electrode is arranged in the outside of the medium tube, grounding electrode setting exists
The inside of medium tube.
For the ease of the flowing of testing liquid, further, the axis of first passage is straight line.
In order to strengthen the ion source of testing liquid, further, one end of the second pipe passes through the first passage
And it extends in the medium tube.
If the user of ion source does not provide satisfactory direct current and alternating current, need to provide following power supply：
Power supply, the power supply provides DC voltage for the conductive contact, and provides alternating current for the high-field electrode
Pressure.
The working method of the above-mentioned open type ion source of the embodiment of the present invention, the working method are：
Give the conductive contact to apply DC voltage, if amplitude is 1KV-5KV, the conductive contact and grounding electrode it
Between form electric field；Apply alternating voltage to the high-field electrode, if amplitude is 1KV-5KV, frequency 50Hz-1MHz；
Testing liquid is entered by first pipe in second pipe, and is sprayed out of described second pipe, in the electricity
Under field action, spraying is formed；
Gas enters from third pipeline in the second channel and first passage, and shape in the region of discharge in medium tube
At plasma, to ionize the sample in the misty testing liquid into the medium tube.
Embodiment 2：
The application examples of open type ion source described in the embodiment of the present invention 1.
In the application examples, the second pipe is capillary glass tube or metal capillary, and inside diameter ranges are 25 μm of -200 μ
M, external diametrical extent are 150 μm -400 μm；The medium tube includes the insulated dielectric tubes such as quartz glass tube, ceramic tube, inside diameter ranges
For 1mm-5mm, external diametrical extent 2mm-6mm；The gas includes the inert gases such as helium, argon gas or nitrogen；Power supply output
DC voltage amplitude is 1KV-5KV, and the alternating voltage amplitude of output is 1KV-5KV, frequency 50Hz-1MHz；First passage
Angle between central axis and the central axis of second channel is right angle；First passage is linearly.
Claims (10)
1. a kind of open type ion source, the open type ion source includes medium tube, high-field electrode and grounding electrode；Its feature exists
In：The open type ion source further comprises：
First connector；
Conductive contact；
Second connector；
Connector, first connector, conductive contact, the second connector and connector are sequentially connected；Have the in the connector
One channel and second channel, the angle between the axis of second channel and the axis of first passage are acute angle or right angle；The medium
Pipe is arranged in the exit of the connector；
First pipe, the first pipe is arranged in first connector, and one end extends in the conductive contact；
Second pipe, the second pipe is arranged in second connector, and one end extends in the conductive contact, another
End extends in the first passage；The distance between the end of first pipe and second pipe in the conductive contact
More than zero；In the second pipe on the flow direction of fluid, the end position of the second pipe in the first passage
Downstream in the junction of the first passage and second channel；
Third connector, the third connector connect the connector；
Third pipeline, the third pipeline is arranged in the third connector, and one end extends in the second channel.
2. open type ion source according to claim 1, it is characterised in that：The axis of first passage is straight line.
3. open type ion source according to claim 1, it is characterised in that：The second pipe is quartz ampoule or stainless steel
Pipe.
4. open type ion source according to claim 1, it is characterised in that：One end of the second pipe passes through described the
One channel simultaneously extends in the medium tube.
5. open type ion source according to claim 1, it is characterised in that：The open type ion source further comprises：
Power supply, the power supply provides DC voltage for the conductive contact, and provides alternating voltage for the high-field electrode.
6. open type ion source according to claim 1, it is characterised in that：First connector has external screw thread, described
Conductive contact has and the matched internal thread of the external screw thread.
7. open type ion source according to claim 1, it is characterised in that：The both ends of second connector have outer spiral shell
Line, the conductive contact and connector are respectively provided with and the matched internal thread of the external screw thread.
8. open type ion source according to claim 5, it is characterised in that：The high-field electrode is arranged in the medium tube
Outside, the grounding electrode is arranged in the inside of the medium tube.
9. according to the working method of any open type ion sources of claim 1-8, the working method is：
Apply DC voltage to the conductive contact, electric field is formed between the conductive contact and grounding electrode；To the height
Piezoelectricity pole applies alternating voltage；
Testing liquid is entered by first pipe in second pipe, and is sprayed out of described second pipe, is made in the electric field
Under, spraying is formed；
Gas enters from third pipeline in the second channel and first passage, and formed in the region of discharge in medium tube etc.
Gas ions, to ionize the sample in the misty testing liquid into the medium tube.
10. working method according to claim 9, it is characterised in that：The amplitude of the DC voltage is 1KV-5KV；Institute
The amplitude for stating alternating voltage is 1KV-5KV, frequency 50Hz-1MHz.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711494194.5A CN108428613B (en) | 2017-12-31 | 2017-12-31 | Open ion source and method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711494194.5A CN108428613B (en) | 2017-12-31 | 2017-12-31 | Open ion source and method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN108428613A true CN108428613A (en) | 2018-08-21 |
| CN108428613B CN108428613B (en) | 2023-08-04 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711494194.5A Active CN108428613B (en) | 2017-12-31 | 2017-12-31 | Open ion source and method |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109813795A (en) * | 2018-12-26 | 2019-05-28 | 宁波大学 | Ion source mass spectrum combination method |
| CN110233094A (en) * | 2019-07-11 | 2019-09-13 | 宁波大学 | Ion source and its working method, application |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090008252A1 (en) * | 2007-07-03 | 2009-01-08 | Amarante Technologies, Inc. | Ozone generating device |
| CN104538276A (en) * | 2014-12-26 | 2015-04-22 | 宁波大学 | Ion source soft ionization device and method under barometric pressure |
| CN208596659U (en) * | 2017-12-31 | 2019-03-12 | 宁波大学 | Open type ion source |
-
2017
- 2017-12-31 CN CN201711494194.5A patent/CN108428613B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090008252A1 (en) * | 2007-07-03 | 2009-01-08 | Amarante Technologies, Inc. | Ozone generating device |
| CN104538276A (en) * | 2014-12-26 | 2015-04-22 | 宁波大学 | Ion source soft ionization device and method under barometric pressure |
| CN208596659U (en) * | 2017-12-31 | 2019-03-12 | 宁波大学 | Open type ion source |
Non-Patent Citations (1)
| Title |
|---|
| 商克峰;王浩;岳帅;李杰;吴彦;: "结构及供电电源对沿面介质阻挡放电装置放电特性及臭氧生成的影响", 电工技术学报, no. 02 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109813795A (en) * | 2018-12-26 | 2019-05-28 | 宁波大学 | Ion source mass spectrum combination method |
| CN110233094A (en) * | 2019-07-11 | 2019-09-13 | 宁波大学 | Ion source and its working method, application |
Also Published As
| Publication number | Publication date |
|---|---|
| CN108428613B (en) | 2023-08-04 |
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