CN108414511B - Tumor urine detection device and method - Google Patents
Tumor urine detection device and method Download PDFInfo
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- CN108414511B CN108414511B CN201810169984.4A CN201810169984A CN108414511B CN 108414511 B CN108414511 B CN 108414511B CN 201810169984 A CN201810169984 A CN 201810169984A CN 108414511 B CN108414511 B CN 108414511B
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Abstract
The invention discloses a tumor urine detection device and a tumor urine detection method, wherein the tumor urine detection device comprises a seat body and a diversion trench arranged in the seat body, wherein the bottom of the diversion trench of the seat body is provided with a liquid discharge hole and a liquid dropping hole; the tapping hole is positioned on one side of the bottom of the diversion trench, and the drip hole is positioned on the other side of the bottom of the diversion trench and is oppositely arranged. The bottom of the diversion trench is provided with an inclined baffle plate, so that urine can be discharged from the liquid discharge hole conveniently. And a conveying belt is arranged below the bottom of the flow guide groove in the seat body. The seat body is provided with a through hole for the conveying belt to pass through, the conveying belt is sleeved on the driven wheel and the driving wheel, and the driving wheel is connected with the driving motor. The method is time-saving, rapid, simple and accurate.
Description
Technical Field
The invention belongs to the technical field of urine detection of tumor patients, and particularly relates to a tumor urine detection device and method.
Background
Cancer, the early discovery and early treatment of the first 4 stages of development can be completely cured, the discovery and treatment in the first three stages can reach the cure rate of 100%. Cancer is feared by the fact that in the first three stages, imaging cannot be detected at all, and even in the middle stage of the tumor, it can only be detected by very specialized physicians with advanced equipment. The world health organization's research suggests that: 1/3 of the cancers are preventable; 1/3 of the cancers can prolong patient life by active treatment; 1/3 of cancer can be cured by early detection, early diagnosis and early treatment. This means that early detection of tumors becomes possible.
Since early detection of cancer is difficult and the mortality rate is high, most cancers are found at middle and advanced stages. The numbers published by the world health organization for oncology research center indicate that: by 2020, tumor patients will increase by 43%. The Chinese Ministry of health disease control department displays the data: the number of tumor diseases is about 200 million and 140 million deaths each year in China, and the number of the tumor diseases is on the rising trend year by year.
1201 thousands of people are diagnosed as cancer, 760 thousands of people die from cancer, the new disease rate of our country in 2011 is 200 thousands of people, the new disease rate of our country's tumor is 285.91/10 ten thousands at present, 6 people are diagnosed as malignant tumor every minute on average every day, and the expert thinks that 40% of cancers have the potential of prevention.
The incidence of cancers of children is increased year by year, and statistics of the international anti-cancer union indicate that the incidence of cancers of children is about one ten thousand, 16 ten thousand children are diagnosed as cancers every year worldwide, and about 9 ten thousand deaths are caused by pain.
According to an investigation and statistics report of the Ministry of health in China, cancer exceeds cardiovascular and cerebrovascular diseases, and becomes the most important disease causing death of residents in cities and countryside in China at present. In recent 20 years, one of every 4-5 deaths in China died from cancer and the leading cause of death. Cancer has become a common and frequently occurring disease.
The cancer urine detection reagent can be accurately detected through urine at the tumor cell starting stage, the early tumor stage and the middle tumor stage (within the range of no monitoring in the benign stage) of cancer, has simple and convenient method and high accuracy, and wins time for the active treatment of people. "
The cancer urine detection reagent has wide application range, is suitable for cancer screening, general investigation and detection of people in all countries and regions, is also suitable for monitoring cancer related diseases (such as infectious liver diseases, chronic digestive tract ulcer and unknown etiology), and can also be used for detecting the treatment effect of cancer patients and tracking and monitoring cancer rehabilitation patients.
Early screening of tumors is a very important means to reduce the incidence and mortality of tumors at present. The current common detection methods comprise various tumor markers, infrared rays, X rays and the like. Tumor markers require hospital blood draws, require specialized equipment for detection, as do infrared and X-ray. The existing screening method all involves various instruments and equipment, and is complex and high in cost. The detection of tumor markers in urine is always a hotspot of international research, and the screening of early tumors by using tumor markers in urine is generally accepted by scientific researchers and consumers.
Disclosure of Invention
In order to solve the above-mentioned defects in the prior art, the present invention aims to provide a tumor urine detection device and method which is time-saving, fast, simple and accurate in detection.
In order to achieve the purpose, the invention adopts the following technical scheme:
a tumor urine detection device comprises a seat body and a diversion trench arranged in the seat body, wherein the bottom of the diversion trench of the seat body is provided with a liquid discharge hole and a liquid dropping hole;
the tapping hole is positioned on one side of the bottom of the diversion trench, and the drip hole is positioned on the other side of the bottom of the diversion trench and is oppositely arranged.
The bottom of the diversion trench is provided with an inclined baffle plate, so that urine can be discharged from the liquid discharge hole conveniently.
And a conveying belt is arranged below the bottom of the flow guide groove in the seat body.
The seat body is provided with a through hole for the conveying belt to pass through, the conveying belt is sleeved on the driven wheel and the driving wheel, and the driving wheel is connected with the driving motor.
And a sealing mechanism for sealing the liquid discharge hole is arranged in the seat body.
A temporary sealing mechanism for sealing the liquid dropping hole is arranged in the base body.
The temporary sealing mechanism comprises a second electric telescopic rod arranged in the seat body and a sealing head arranged on the second electric telescopic rod, a diversion inclined plate is arranged at the outlet of the liquid dropping hole, and the sealing head is matched with the inclined guide plate.
The base body guide groove is internally provided with a guide groove temporary sealing mechanism, the guide groove temporary sealing mechanism comprises a through hole which is formed in the side wall of the guide groove and used for the sealing plate to pass through, a third electric telescopic rod used for pushing the sealing plate is arranged in the base body, and the sealing plate is arranged in an inclined mode so that liquid on the sealing plate can flow down conveniently.
The sealing mechanism comprises an electric telescopic rod arranged in the seat body and a rubber sealing head arranged on the electric telescopic rod, and the rubber sealing head is matched with the inclined guide plate.
The conveying belt is provided with a liquid receiving cup, and the upper port of the liquid receiving cup is positioned at the lower part of the liquid dropping hole.
An inclined guide plate is arranged at a liquid discharge hole at the bottom of the guide groove to prevent liquid from being stained on the conveying belt.
The conveyer belt is connected with the liquid receiving cup through a fixing mechanism.
The fixing mechanism comprises a left magnet block and a right magnet block which are arranged on two sides of the conveying belt, a left magnet matched with the left magnet block is arranged below the liquid receiving cup, and a right magnet matched with the right magnet block is arranged below the liquid receiving cup.
And a liquid level detection mechanism is arranged on the liquid receiving cup.
The liquid level detection mechanism adopts a liquid level sensor.
The liquid level detection mechanism is including setting up leading electrical pillar under connecing liquid cup bottom, it leads electrical pillar on being equipped with on the liquid cup lateral wall to connect, left side magnet one side is equipped with left conducting strip, right side magnet one side is equipped with right conducting strip, be equipped with left conducting strip matched with left busbar on the conveyer belt, be equipped with right conducting strip matched with right busbar on the conveyer belt, pedestal one side is equipped with the left conducting pressing piece that contacts with the upper left busbar of conveyer belt through the bracing piece, pedestal one side is equipped with the right conducting pressing piece that contacts with the upper right busbar of conveyer belt through the bracing piece, left side conducting pressing piece, right conducting pressing piece pass through the wire with the power and are connected, are equipped with current sensor on the wire, current sensor.
And the programmable controller is connected with the driving motor.
And a supporting plate is arranged below the conveying belt.
And the upper part of the conveying belt is provided with a quantitative test solution adding mechanism for adding test solution to the solution receiving cup.
The quantitative adding mechanism for the inspection liquid comprises a sleeve arranged on the upper portion of a liquid receiving cup through a support, an electric push rod is arranged in the sleeve, a bayonet for clamping the syringe is arranged on one side below the sleeve, and a positioning groove for sleeving the end portion of a piston rod of the syringe is arranged on the telescopic portion of the electric push rod.
And a limiting groove for clamping the syringe handle is formed in the inner side of the lower part of the sleeve.
The seat body is provided with a cover body, and a drying mechanism is arranged in the cover body.
The drying mechanism comprises an air blower arranged in the cover body and an electric heating wire arranged at an air outlet of the cover body. The blower and the electric heating wire are both connected with a programmable controller.
The seat body is provided with a flushing mechanism which can adopt a closestool type flushing mechanism.
A tumor urine detection method comprises the following steps:
1) the liquid receiving cup is placed on the conveyor belt, the magnet block fixes the liquid receiving cup, the driving motor works to enable the liquid receiving opening of the liquid receiving cup to be located below the liquid dropping hole, the electric telescopic rod is in a contraction state at the moment, the liquid discharging hole is in an opening state, the second electric telescopic rod works to press the sealing head on the inclined guide plate, and the liquid dropping hole is in a sealing state;
2) the injector is clamped into the sleeve, the electric push rod works to clamp the telescopic end of the electric push rod into the end part of the piston rod,
3) when the urine in the front section is discharged, the seat body switch is switched on to enable the electric telescopic rod to work to seal the liquid discharging hole, meanwhile, the second electric telescopic rod is contracted to open the liquid dropping hole, the patient continues to discharge the urine, after the urine in the middle section is discharged, the seat body switch is switched on, the third electric telescopic rod works, the sealing plate seals the diversion trench, the urine in the last section flows on the sealing plate, when the set value of the liquid level is reached, the liquid level sensor transmits a signal to the programmable controller, and the driving motor works to drive the conveying belt to move, so that the liquid receiving cup is positioned at the lower part of the injector;
4) the electric push rod works to drive the piston rod to move downwards, so that the test solution is dripped into the solution receiving cup, and when the added test solution meets the requirement, the electric push rod stops working; observing the color of the precipitate;
5) after the precipitate is colored, the driving motor continues to work to drive the liquid receiving cup to rotate downwards, the reaction liquid is poured into the filtering tank, a filtering net is arranged in the filtering tank, the upper part of the recovery tank is provided with a baffle rod, and after the liquid receiving cup contacts the baffle rod, the liquid receiving cup does not contact the magnet block and falls into the recovery tank;
6) electric telescopic handle and second electric telescopic handle all contract, and drain hole and drip hole are all opened, press the mechanism button of washing by water, wash by water under the effect of gravity with the closing plate buckling, with the diversion trench in the urine wash clean back, air-blower and heating wire work are dried with the moisture in the diversion trench.
The driving motor continues to work to drive the liquid receiving cup to rotate downwards, reaction liquid is poured into the filtering tank, a filtering screen is arranged in the filtering tank and used for receiving solids in the liquid, a liquid receiving cup recycling groove is arranged on the left side of the filtering tank, a blocking rod is arranged on the upper portion of the recycling groove, and when the liquid receiving cup contacts the blocking rod, the liquid receiving cup does not contact with the magnet block and drops into the recycling groove.
According to the urine detection device, the liquid receiving cup is made of transparent materials, only the liquid receiving cup needs to be placed on the magnet block on the conveying belt, one liquid receiving cup is recovered, the flushing mechanism washes out urine in the diversion trench, then the blower and the electric heating wire work, and moisture in the diversion trench is dried; the other liquid receiving cup can be placed on the conveying belt to continue detection, the magnet block fixes the liquid receiving cup, the programmable controller controls the driving motor to work so that the liquid receiving port of the liquid receiving cup is positioned below the liquid dripping hole, and the programmable controller controls the electric telescopic rod to work so as to press the rubber sealing head on the inclined guide plate; the injector is clamped into the sleeve, the programmable controller controls the electric push rod to work to clamp the telescopic end of the electric push rod into the end part of the piston rod, a patient sits on the seat body to urinate, the liquid discharge hole stops the urine at the moment and only drops into the liquid receiving cup from the liquid dropping hole, when the liquid in the liquid receiving cup is contacted with the upper conductive post on the liquid receiving cup, the power supply forms a loop, the current sensor detects the current, and the programmable controller controls the driving motor to work to drive the conveying belt to move, so that the liquid receiving cup is positioned at the lower part of the injector; the programmable controller controls the electric push rod to work to drive the piston rod to move downwards, so that the test solution is dripped into the liquid receiving cup, the programmable controller controls the electric push rod to move downwards for a required distance, meanwhile, the injector is enabled to extrude quantitative detection solution, the quantitative detection solution is mixed with quantitative urine in the cup body, the amounts of the detection solution and the urine are matched, the detection result is more accurate, and after the added test solution meets the requirement, the programmable controller controls the electric push rod to stop working, and the color change of sediments in the liquid receiving cup is observed.
Drawings
FIG. 1 is a schematic front view of the present invention;
FIG. 2 is a schematic top view of the present invention;
FIG. 3 is a schematic side view of the present invention;
FIG. 4 is a schematic view of the connecting structure of the liquid receiving cup and the conveyer belt of the present invention;
FIG. 5 is a schematic structural view of a quantitative test solution adding mechanism according to the present invention;
fig. 6 is a schematic cross-sectional view of a conductive strip and a conductive pad of the present invention.
Detailed Description
The invention is further described below with reference to the figures and examples.
The first embodiment is as follows: as shown in fig. 1-6, an internal tumor urine detection device comprises a base 18 and a diversion trench 6 disposed in the base 18, wherein a tapping hole 9 and a dropping hole 11 are disposed at the bottom of the diversion trench 6 of the base 18,
the liquid discharging hole 9 is located on one side of the bottom 10 of the diversion trench, the liquid dropping hole is located on the other side of the bottom 10 of the diversion trench, and the liquid discharging hole and the liquid dropping hole are oppositely arranged.
The bottom 10 of the diversion trench 6 is provided with a urine diversion inclined baffle 20 for facilitating the discharge of urine from the liquid discharge hole.
A conveying belt is arranged below the bottom 10 of the flow guide groove of the seat body 18, and the inclined baffle plate not only plays a role in flow guide, but also more importantly prevents urine from being dripped on the conveying belt.
The base body 18 is provided with a through hole 23 for the conveying belt 16 to pass through, the conveying belt 16 is sleeved on the driven wheel 60 and the driving wheel 22, and the driving wheel 22 is connected with the driving motor 64.
A sealing mechanism for sealing the tapping hole is arranged in the seat body 18.
The sealing mechanism comprises an electric telescopic rod 7 arranged in the seat body and a rubber sealing head 8 arranged on the electric telescopic rod 7, the rubber sealing head is matched with the inclined guide plate, the upper side of the rubber sealing head is contacted with the bottom 61 of the flow guide body, and after the electric telescopic rod is contracted, a gap between the upper side of the rubber sealing head and the bottom of the flow guide body is used for flushing water to pass through, so that the rubber sealing head is convenient to clean; when the sealing device needs to be sealed, the head of the rubber sealing head deforms to seal the liquid discharge hole under the action of the inclined baffle and the pushing force of the electric telescopic rod.
The conveying belt is provided with a liquid receiving cup 12, the upper port of the liquid receiving cup is positioned at the lower part of the liquid dropping hole, the accommodating cavity 63 of the liquid receiving cup is positioned at one side of the liquid receiving cup, and the other side of the liquid receiving cup 12 is provided with a balancing weight 62, so that on one hand, urine collection is facilitated, and on the other hand, stable and balanced operation of the liquid receiving cup on the conveying belt is facilitated.
An inclined guide plate 20 is arranged at a liquid discharge hole at the bottom of the guide groove to prevent liquid from being stained on the conveying belt.
The conveyer belt 16 is connected with the liquid receiving cup through a fixing mechanism.
The fixing mechanism comprises a left magnet block 34 and a right magnet block 14 which are arranged on two sides of the conveying belt 16, a left magnet 33 matched with the left magnet block 34 is arranged below the liquid receiving cup, and a right magnet 13 matched with the right magnet block 14 is arranged below the liquid receiving cup.
The liquid level detection mechanism adopts a liquid level sensor.
The drive motor 64 is connected to a programmable controller.
And a supporting plate 17 is arranged below the conveying belt, so that the conveying belt runs stably.
And the upper part of the conveying belt is provided with a quantitative test solution adding mechanism for adding test solution to the solution receiving cup.
The quantitative adding mechanism for the inspection liquid comprises a sleeve 50 arranged on the upper portion of the liquid receiving cup 12 through a support 65, an electric push rod 24 is arranged in the sleeve 50, a bayonet 52 for clamping the syringe is arranged on one side below the sleeve 50, and a positioning groove for sleeving the end portion of a piston rod 25 of the syringe 26 is formed in the telescopic portion of the electric push rod.
The sleeve is fixed on the seat body through the bracket.
The inner side of the lower part of the sleeve is provided with a limiting groove for clamping the syringe handle 51.
The seat body is provided with a cover body, and a drying mechanism is arranged in the cover body.
The drying mechanism comprises an air blower 5 arranged in the cover body 1 and an electric heating wire 4 arranged at an air outlet 3 of the cover body. The blower and the electric heating wire are both connected with a programmable controller.
The seat body is provided with a flushing mechanism 19 which can adopt a closestool type flushing mechanism.
The drain 2 of pedestal is connected with the downcomer, is equipped with the guide plate that is convenient for urine to flow into the drain in the pedestal.
Example two: as shown in fig. 1-6, an internal tumor urine detection device comprises a base 18 and a diversion trench 6 disposed in the base 18, wherein a tapping hole 9 and a dropping hole 11 are disposed at the bottom of the diversion trench 6 of the base 18,
the tapping hole 9 is positioned on one side of the bottom 10 of the diversion trench, and the drip hole is positioned on the other side of the bottom 10 of the diversion trench.
The bottom 10 of the diversion trench 6 is provided with a urine diversion inclined baffle 20 for facilitating the discharge of urine from the liquid discharge hole.
A conveying belt is arranged below the bottom 10 of the flow guide groove of the seat body 18, and the inclined baffle plate not only plays a role in flow guide, but also more importantly prevents urine from being dripped on the conveying belt.
The base body 18 is provided with a through hole 23 for the conveying belt 16 to pass through, the conveying belt 16 is sleeved on the driven wheel 60 and the driving wheel 22, and the driving wheel 22 is connected with the driving motor 64.
A sealing mechanism for sealing the tapping hole is arranged in the seat body 18.
The sealing mechanism comprises an electric telescopic rod 7 arranged in the seat body and a rubber sealing head 8 arranged on the electric telescopic rod 7, the rubber sealing head is matched with the inclined guide plate, the upper side of the rubber sealing head is contacted with the bottom 61 of the flow guide body, and after the electric telescopic rod is contracted, a gap between the upper side of the rubber sealing head and the bottom of the flow guide body is used for flushing water to pass through, so that the rubber sealing head is convenient to clean; when the sealing device needs to be sealed, the head of the rubber sealing head deforms to seal the liquid discharge hole under the action of the inclined baffle and the pushing force of the electric telescopic rod.
The conveying belt is provided with a liquid receiving cup 12, the upper port of the liquid receiving cup is positioned at the lower part of the liquid dropping hole, the accommodating cavity 63 of the liquid receiving cup is positioned at one side of the liquid receiving cup, and the other side of the liquid receiving cup 12 is provided with a balancing weight 62, so that on one hand, urine collection is facilitated, and on the other hand, stable and balanced operation of the liquid receiving cup on the conveying belt is facilitated.
An inclined guide plate 20 is arranged at a liquid discharge hole at the bottom of the guide groove to prevent liquid from being stained on the conveying belt.
The conveyer belt 16 is connected with the liquid receiving cup through a fixing mechanism.
The fixing mechanism comprises a left magnet block 34 and a right magnet block 14 which are arranged on two sides of the conveying belt 16, a left magnet 33 matched with the left magnet block 34 is arranged below the liquid receiving cup, and a right magnet 13 matched with the right magnet block 14 is arranged below the liquid receiving cup.
And a liquid level detection mechanism is arranged on the liquid receiving cup.
The liquid level detection mechanism comprises a lower conductive column 45 arranged at the bottom of the liquid receiving cup, an upper conductive column 35 is arranged on the side wall of the liquid receiving cup, a left conductive sheet 36 connected with the upper conductive column 35 is arranged on one side of a left magnet, a right conductive sheet 37 connected with the lower conductive column 45 is arranged on one side of a right magnet, a left conductive bar 46 matched with the left conductive sheet 36 is arranged on the conveying belt, a right conductive bar 47 matched with the right conductive sheet 37 is arranged on the conveying belt, a left conductive pressing sheet 31 contacted with the left conductive bar on the conveying belt is arranged on one side of the seat body through a supporting rod, a right conductive pressing sheet 21 contacted with the right conductive bar on the conveying belt is arranged on one side of the seat body through a supporting rod, the left conductive pressing sheet and the right conductive pressing sheet are connected with a power supply 49.
The programmable controller is connected to a drive motor 64.
And a supporting plate 17 is arranged below the conveying belt, so that the conveying belt runs stably.
And the upper part of the conveying belt is provided with a quantitative test solution adding mechanism for adding test solution to the solution receiving cup.
The quantitative adding mechanism for the inspection liquid comprises a sleeve 50 arranged on the upper portion of the liquid receiving cup 12 through a support 65, an electric push rod 24 is arranged in the sleeve 50, a bayonet 52 for clamping the syringe is arranged on one side below the sleeve 50, and a positioning groove for sleeving the end portion of a piston rod 25 of the syringe 26 is formed in the telescopic portion of the electric push rod.
The sleeve is fixed on the seat body through the bracket.
The inner side of the lower part of the sleeve is provided with a limiting groove for clamping the syringe handle 51.
The seat body is provided with a cover body, and a drying mechanism is arranged in the cover body.
The drying mechanism comprises an air blower 5 arranged in the cover body 1 and an electric heating wire 4 arranged at an air outlet 3 of the cover body. The blower and the electric heating wire are both connected with a programmable controller.
The seat body is provided with a flushing mechanism 19 which can adopt a closestool type flushing mechanism.
The drain 2 of pedestal is connected with the downcomer, is equipped with the guide plate that is convenient for urine to flow into the drain in the pedestal.
A tumor urine detection method comprises the following steps:
1) the liquid receiving cup is placed on the conveyor belt, the magnet block fixes the liquid receiving cup, the driving motor works to enable the liquid receiving opening of the liquid receiving cup to be located below the liquid dropping hole, the electric telescopic rod is in a contraction state at the moment, the liquid discharging hole is in an opening state, the second electric telescopic rod works to press the sealing head on the inclined guide plate, and the liquid dropping hole is in a sealing state;
2) the injector is clamped into the sleeve, the electric push rod works to clamp the telescopic end of the electric push rod into the end part of the piston rod,
3) when the urine in the front section is discharged, the seat body switch is switched on to enable the electric telescopic rod to work to seal the liquid discharging hole, meanwhile, the second electric telescopic rod is contracted to open the liquid dropping hole, the patient continues to discharge the urine, after the urine in the middle section is discharged, the seat body switch is switched on, the third electric telescopic rod works, the sealing plate seals the diversion trench, the urine in the last section flows on the sealing plate, when the set value of the liquid level is reached, the liquid level sensor transmits a signal to the programmable controller, and the driving motor works to drive the conveying belt to move, so that the liquid receiving cup is positioned at the lower part of the injector;
4) the electric push rod works to drive the piston rod to move downwards, so that the test solution is dripped into the solution receiving cup, and when the added test solution meets the requirement, the electric push rod stops working; observing the color of the precipitate;
5) after the precipitate is colored, the driving motor continues to work to drive the liquid receiving cup to rotate downwards, the reaction liquid is poured into the filtering tank 29, the filtering screen 30 is arranged in the filtering tank, the baffle rod 66 is arranged at the upper part of the recovery tank 28, and after the liquid receiving cup contacts the baffle rod 66, the liquid receiving cup does not contact the magnet block and falls into the recovery tank;
6) electric telescopic handle and second electric telescopic handle all contract, and drain hole and drip hole are all opened, press the mechanism button of washing by water, wash by water under the effect of gravity with the closing plate buckling, and third electric telescopic handle work is with the closing plate pull-back a bit, and the steam of being convenient for is dried guiding gutter and closing plate, with the guiding gutter in the urine wash clean back, air-blower and heating wire work are dried the moisture in the guiding gutter.
The sealing plate is made of rubber materials and has certain strength, 1000ml of water cannot bend the sealing plate, and the sealing plate is connected with the side wall hole of the flow guide groove in a sealing mode. For example, when a person urinates 600ml for 9 seconds, 200ml in the first 3 seconds is discharged as fore-stream urine, 200ml in the middle 3 seconds is middle-stream urine, and 200ml in the last 3 seconds is end-stream urine, which may affect the use of the urine due to urinary tract infection of the patient.
The driving motor continues to work to drive the liquid receiving cup to rotate downwards, reaction liquid is poured into the filtering tank, a filtering screen is arranged in the filtering tank and used for receiving solids in the liquid, a liquid receiving cup recycling groove is arranged on the left side of the filtering tank, a blocking rod is arranged on the upper portion of the recycling groove, and when the liquid receiving cup contacts the blocking rod, the liquid receiving cup does not contact with the magnet block and drops into the recycling groove.
According to the urine detection device, the liquid receiving cup is made of transparent materials, only the liquid receiving cup needs to be placed on the magnet block on the conveying belt, one liquid receiving cup is recovered, the flushing mechanism washes out urine in the diversion trench, then the blower and the electric heating wire work, and moisture in the diversion trench is dried; the other liquid receiving cup can be placed on the conveying belt to continue detection, the magnet block fixes the liquid receiving cup, the programmable controller controls the driving motor to work so that the liquid receiving port of the liquid receiving cup is positioned below the liquid dripping hole, and the programmable controller controls the electric telescopic rod to work so as to press the rubber sealing head on the inclined guide plate; the injector is clamped into the sleeve, the programmable controller controls the electric push rod to work to clamp the telescopic end of the electric push rod into the end part of the piston rod, a patient sits on the seat body to urinate, the liquid discharge hole blocks the current, the urine can only be dripped into the liquid receiving cup from the liquid dropping hole, when the liquid in the liquid receiving cup is contacted with the upper conductive post on the liquid receiving cup, the power supply forms a loop, the current sensor detects the current, the programmable controller controls the driving motor to work to drive the conveying belt to move, and the containing cavity of the liquid receiving cup is positioned at the lower part of the injector; the programmable controller controls the electric push rod to work to drive the piston rod to move downwards, so that the test solution is dripped into the liquid receiving cup, the programmable controller controls the electric push rod to move downwards for a required distance, meanwhile, the injector is enabled to extrude quantitative detection solution, the quantitative detection solution is mixed with quantitative urine in the cup body, the amounts of the detection solution and the urine are matched, the detection result is more accurate, and after the added test solution meets the requirement, the programmable controller controls the electric push rod to stop working, and the color change of sediments in the liquid receiving cup is observed.
Example three: as shown in fig. 1-6 and fig. 1-6, an internal tumor urine detection device comprises a base 18 and a diversion trench 6 disposed in the base 18, wherein a tapping hole 9 and a dropping hole 11 are disposed at the bottom of the diversion trench 6 of the base 18,
the tapping hole 9 is positioned on one side of the bottom 10 of the diversion trench, and the dropping hole is positioned on the other side of the bottom 10 of the diversion trench and is oppositely arranged.
The bottom 10 of the diversion trench 6 is provided with a urine diversion inclined baffle 20 for facilitating the discharge of urine from the liquid discharge hole.
A conveying belt is arranged below the bottom 10 of the flow guide groove of the seat body 18, and the inclined baffle plate not only plays a role in flow guide, but also more importantly prevents urine from being dripped on the conveying belt.
The base body 18 is provided with a through hole 23 for the conveying belt 16 to pass through, the conveying belt 16 is sleeved on the driven wheel 60 and the driving wheel 22, and the driving wheel 22 is connected with the driving motor 64.
A sealing mechanism for sealing the tapping hole is arranged in the seat body 18.
A temporary sealing mechanism for sealing the liquid dropping hole is arranged in the base body.
The temporary sealing mechanism comprises a second electric telescopic rod 73 arranged in the seat body and a sealing head 72 arranged on the second electric telescopic rod, a diversion inclined plate is arranged at the liquid dropping hole, and the sealing head 72 is matched with the inclined guide plate.
The base body is characterized in that a guide groove temporary sealing mechanism is arranged in the guide groove of the base body, the guide groove temporary sealing mechanism comprises a through hole which is formed in the side wall of the guide groove and used for a sealing plate 71 to pass through, a third electric telescopic rod 70 used for pushing the sealing plate is arranged in the base body, and the sealing plate is arranged in an inclined mode so that liquid on the sealing plate can flow down conveniently.
The sealing mechanism comprises an electric telescopic rod 7 arranged in the seat body and a rubber sealing head 8 arranged on the electric telescopic rod 7, the rubber sealing head is matched with the inclined guide plate, the upper side of the rubber sealing head is contacted with the bottom 61 of the flow guide body, and after the electric telescopic rod is contracted, a gap between the upper side of the rubber sealing head and the bottom of the flow guide body is used for flushing water to pass through, so that the rubber sealing head is convenient to clean; when the sealing device needs to be sealed, the head of the rubber sealing head deforms to seal the liquid discharge hole under the action of the inclined baffle and the pushing force of the electric telescopic rod.
The conveying belt is provided with a liquid receiving cup 12, the upper port of the liquid receiving cup is positioned at the lower part of the liquid dropping hole, the accommodating cavity 63 of the liquid receiving cup is positioned at one side of the liquid receiving cup, and the other side of the liquid receiving cup 12 is provided with a balancing weight 62, so that on one hand, urine collection is facilitated, and on the other hand, stable and balanced operation of the liquid receiving cup on the conveying belt is facilitated.
An inclined guide plate 20 is arranged at a liquid discharge hole at the bottom of the guide groove to prevent liquid from being stained on the conveying belt.
The conveyer belt 16 is connected with the liquid receiving cup through a fixing mechanism.
The fixing mechanism comprises a left magnet block 34 and a right magnet block 14 which are arranged on two sides of the conveying belt 16, a left magnet 33 matched with the left magnet block 34 is arranged below the liquid receiving cup, and a right magnet 13 matched with the right magnet block 14 is arranged below the liquid receiving cup.
And a liquid level detection mechanism is arranged on the liquid receiving cup.
The liquid level detection mechanism comprises a lower conductive column 45 arranged at the bottom of the liquid receiving cup, an upper conductive column 35 is arranged on the side wall of the liquid receiving cup, a left conductive sheet 36 connected with the upper conductive column 35 is arranged on one side of a left magnet, a right conductive sheet 37 connected with the lower conductive column 45 is arranged on one side of a right magnet, a left conductive bar 46 matched with the left conductive sheet 36 is arranged on the conveying belt, a right conductive bar 47 matched with the right conductive sheet 37 is arranged on the conveying belt, a left conductive pressing sheet 31 contacted with the left conductive bar on the conveying belt is arranged on one side of the seat body through a supporting rod, a right conductive pressing sheet 21 contacted with the right conductive bar on the conveying belt is arranged on one side of the seat body through a supporting rod, the left conductive pressing sheet and the right conductive pressing sheet are connected with a power supply 49.
The programmable controller is connected to a drive motor 64.
And a supporting plate 17 is arranged below the conveying belt, so that the conveying belt runs stably.
And the upper part of the conveying belt is provided with a quantitative test solution adding mechanism for adding test solution to the solution receiving cup.
The quantitative adding mechanism for the inspection liquid comprises a sleeve 50 arranged on the upper portion of the liquid receiving cup 12 through a support 65, an electric push rod 24 is arranged in the sleeve 50, a bayonet 52 for clamping the syringe is arranged on one side below the sleeve 50, and a positioning groove for sleeving the end portion of a piston rod 25 of the syringe 26 is formed in the telescopic portion of the electric push rod.
The sleeve is fixed on the seat body through the bracket.
The inner side of the lower part of the sleeve is provided with a limiting groove for clamping the syringe handle 51.
The seat body is provided with a cover body, and a drying mechanism is arranged in the cover body.
The drying mechanism comprises an air blower 5 arranged in the cover body 1 and an electric heating wire 4 arranged at an air outlet 3 of the cover body. The blower and the electric heating wire are both connected with a programmable controller.
The seat body is provided with an annular cushion 75, a soft cable type electric heating element is arranged in the cushion, the soft cable type electric heating element is woven into the cushion in a coil snake shape or sewn into the cushion, and the soft cable type electric heating element is connected with a temperature control switch. The patient can use the device conveniently, the cold seat body cannot be directly contacted with the human body, the patient cannot be stimulated, and the detection result is not influenced.
The upper part of the lower guide plate of the seat body is provided with an L-shaped air duct 76, and the L-shaped air duct can prevent liquid from overflowing and is convenient for gas to be discharged.
The seat body is provided with a flushing mechanism 19 which can adopt a closestool type flushing mechanism.
The drain 2 of the seat body is connected with a sewer pipe, and a guide plate 69 which is convenient for urine to flow into the drain is arranged in the seat body.
The cross section of the diversion trench is rectangular, so that the sealing plate is convenient to seal.
A tumor urine detection method comprises the following steps:
1) the liquid receiving cup is placed on the conveyor belt, the magnet block fixes the liquid receiving cup, the driving motor works to enable the liquid receiving opening of the liquid receiving cup to be located below the liquid dropping hole, the electric telescopic rod is in a contraction state at the moment, the liquid discharging hole is in an opening state, the second electric telescopic rod works to press the sealing head on the inclined guide plate, and the liquid dropping hole is in a sealing state;
2) the injector is clamped into the sleeve, the electric push rod works to clamp the telescopic end of the electric push rod into the end part of the piston rod,
3) when the middle section of urine is discharged, the base switch is switched on to enable the electric telescopic rod to work to seal the liquid discharging hole, meanwhile, the second electric telescopic rod is contracted to open the liquid dropping hole, the patient continues to urinate, after the middle section of urine is discharged, the base switch is switched on, the third electric telescopic rod works, the sealing plate seals the diversion trench, the tail section of urine flows on the sealing plate, when the liquid in the liquid receiving cup is contacted with the upper conductive post on the liquid receiving cup, the power supply forms a loop, the current sensor detects current, the driving motor works to drive the conveying belt to move, and the liquid receiving cup is positioned at the lower part of the injector;
4) the electric push rod works to drive the piston rod to move downwards, so that the test solution is dripped into the solution receiving cup, and when the added test solution meets the requirement, the electric push rod stops working; observing the color of the precipitate;
5) after the precipitate is colored, the driving motor continues to work to drive the liquid receiving cup to rotate downwards, the reaction liquid is poured into the filtering tank 29, the filtering screen 30 is arranged in the filtering tank, the baffle rod 66 is arranged at the upper part of the recovery tank 28, and after the liquid receiving cup contacts the baffle rod 66, the liquid receiving cup does not contact the magnet block and falls into the recovery tank;
6) electric telescopic handle and second electric telescopic handle all contract, and drain hole and drip hole are all opened, press the mechanism button of washing by water, wash by water under the effect of gravity with the closing plate buckling, with the diversion trench in the urine wash clean back, air-blower and heating wire work are dried with the moisture in the diversion trench.
The sealing plate is made of rubber materials and has certain strength, 1000ml of water cannot bend the sealing plate, and the sealing plate is connected with the side wall hole of the flow guide groove in a sealing mode. For example, when a person urinates 600ml for 9 seconds, 200ml in the first 3 seconds is discharged as fore-stream urine, 200ml in the middle 3 seconds is middle-stream urine, and 200ml in the last 3 seconds is end-stream urine, which may affect the use of the urine due to urinary tract infection of the patient.
After the sealing plate is washed clean, the third electric telescopic rod is contracted, so that drying is facilitated.
The white or light yellow precipitate is negative and is in a healthy state;
the precipitate is light red and is weak positive, and needs to be vigilant and interference eliminated, and the first recheck is pre-picked after 2-3 days;
the red precipitate is positive, needs to be vigilant, eliminates interference, and can be rechecked after 2-3 days;
the brick red color of the precipitate is strong positive (alarm), and further detailed examination is required to be carried out in a hospital.
The detection solutions of examples 1 to 3, which used cancer urine detection reagents, a cancer urine detection reagent for early detection of tumors, were successfully developed in 2005 over a period of ten years and were approved by the national food and drug administration. Product name: the p-hydroxyphenylalanine (tyrosine) urine detection reagent is early discovered and early screened, and is the key for treating tumors. The development of tumors is divided into 5 stages: benign, tumor cell initiation phase, early tumor stage, intermediate tumor stage, and late tumor stage. Reagents produced by Glan biotechnology (Shanghai) Co., Ltd can also be used.
The driving motor continues to work to drive the liquid receiving cup to rotate downwards, reaction liquid is poured into the filtering tank, a filtering screen is arranged in the filtering tank and used for receiving solids in the liquid, a liquid receiving cup recycling groove is arranged on the left side of the filtering tank, a blocking rod is arranged on the upper portion of the recycling groove, and when the liquid receiving cup contacts the blocking rod, the liquid receiving cup does not contact with the magnet block and drops into the recycling groove.
According to the urine detection device, the liquid receiving cup is made of transparent materials, only the liquid receiving cup needs to be placed on the magnet block on the conveying belt, one liquid receiving cup is recovered, the flushing mechanism washes out urine in the diversion trench, then the blower and the electric heating wire work, and moisture in the diversion trench is dried; the other liquid receiving cup can be placed on the conveying belt to continue detection, the magnet block fixes the liquid receiving cup, the programmable controller controls the driving motor to work so that the liquid receiving port of the liquid receiving cup is positioned below the liquid dripping hole, and the programmable controller controls the electric telescopic rod to work so as to press the rubber sealing head on the inclined guide plate; the injector is clamped into the sleeve, the programmable controller controls the electric push rod to work to clamp the telescopic end of the electric push rod into the end part of the piston rod, a patient sits on the seat body to urinate, the liquid discharge hole stops the urine at the moment and only drops into the liquid receiving cup from the liquid dropping hole, when the liquid in the liquid receiving cup is contacted with the upper conductive post on the liquid receiving cup, the power supply forms a loop, the current sensor detects the current, and the programmable controller controls the driving motor to work to drive the conveying belt to move, so that the liquid receiving cup is positioned at the lower part of the injector; the programmable controller controls the electric push rod to work to drive the piston rod to move downwards, so that the test solution is dripped into the liquid receiving cup, the programmable controller controls the electric push rod to move downwards for a required distance, the injector is enabled to extrude quantitative test solution, the quantitative test solution is mixed with the quantitative urine in the cup body, the amounts of the test solution and the urine are matched, the test result is more accurate, and when the added test solution meets the requirement, the programmable controller controls the electric push rod to stop working, and the color change of precipitates in the liquid receiving cup is observed.
Finally, the above embodiments are only used for illustrating the technical solutions of the present invention and not for limiting, and other modifications or equivalent substitutions made by the technical solutions of the present invention by those of ordinary skill in the art should be covered within the scope of the claims of the present invention as long as they do not depart from the spirit and scope of the technical solutions of the present invention.
Claims (2)
1. A tumor urine detection device is characterized in that: the urine drainage seat comprises a seat body and a diversion trench arranged in the seat body, wherein the bottom of the diversion trench of the seat body is provided with a drainage hole and a drip hole, the drainage hole is positioned on one side of the bottom of the diversion trench, the drip hole is positioned on the other side of the bottom of the diversion trench and is oppositely arranged, and the bottom of the diversion trench is provided with a first inclined guide plate for facilitating the discharge of urine from the drainage hole; the seat body is internally provided with a sealing mechanism for sealing the liquid discharge hole, the sealing mechanism comprises a first electric telescopic rod arranged in the seat body and a rubber sealing head arranged on the first electric telescopic rod, the rubber sealing head is matched with the first inclined guide plate, and after the first electric telescopic rod is contracted, washing water passes through a gap between the upper side of the rubber sealing head and the bottom of the diversion trench, so that the rubber sealing head is convenient to clean; when sealing is needed, the rubber sealing head deforms under the action of the thrust of the first inclined guide plate and the first electric telescopic rod to seal the liquid discharging hole; the temporary sealing mechanism comprises a second electric telescopic rod arranged in the seat body and a sealing head arranged on the second electric telescopic rod, a second inclined guide plate is arranged at the liquid dropping hole, and the sealing head is matched with the second inclined guide plate; a diversion trench temporary sealing mechanism is arranged in the diversion trench of the seat body and comprises a through hole which is arranged on the side wall of the diversion trench and through which the sealing plate passes, a third electric telescopic rod for pushing the sealing plate is arranged in the seat body, and the sealing plate is obliquely arranged so as to facilitate the liquid on the sealing plate to flow down;
a conveying belt is arranged below the bottom of the flow guide groove in the seat body; the seat body is provided with a through hole for the conveying belt to pass through, the conveying belt is sleeved on the driven wheel and the driving wheel, and the driving wheel is connected with the driving motor;
the conveying belt is provided with a liquid receiving cup, and the upper port of the liquid receiving cup is positioned at the lower part of the liquid dropping hole; the conveying belt is connected with the liquid receiving cup through a fixing mechanism, the fixing mechanism comprises a left magnet block and a right magnet block which are arranged on two sides of the conveying belt, and a left magnet matched with the left magnet block and a right magnet matched with the right magnet block are arranged below the liquid receiving cup; a liquid level sensor is arranged on the liquid receiving cup;
the upper part of the conveying belt is provided with a quantitative test liquid adding mechanism for adding test liquid to the liquid receiving cup, the quantitative test liquid adding mechanism comprises a sleeve arranged on the upper part of the liquid receiving cup through a support, an electric push rod is arranged in the sleeve, a bayonet for clamping an injector is arranged on one side below the sleeve, a positioning groove for sleeving the end part of a piston rod of the injector is arranged at the telescopic end of the electric push rod, and the sleeve is fixed on the seat body through the support;
a filter tank is arranged below the right end of the conveyor belt, a liquid receiving cup recovery tank is arranged on the left side of the filter tank, and a stop rod is arranged at the upper part of the recovery tank;
the seat body is provided with a flushing mechanism and a cover body, and a drying mechanism is arranged in the cover body; the drying mechanism comprises an air blower arranged in the cover body and an electric heating wire arranged at an air outlet of the cover body.
2. A tumor urine detection method based on the device of claim 1, which comprises the following steps:
1) the liquid receiving cup is placed on the conveyor belt, the magnet block fixes the liquid receiving cup, the driving motor works to enable the liquid receiving opening of the liquid receiving cup to be located below the liquid dropping hole, the first electric telescopic rod is in a contraction state at the moment, the liquid discharging hole is in an opening state, the second electric telescopic rod works to press the sealing head on the second inclined guide plate, and the liquid dropping hole is in a sealing state;
2) the injector is clamped into the sleeve, the electric push rod works to clamp the telescopic end of the electric push rod into the end part of the piston rod,
3) when the middle section of urine is discharged, the seat body switch is switched on to enable the first electric telescopic rod to work to seal the liquid discharging hole, meanwhile, the second electric telescopic rod is contracted to open the liquid dropping hole, the patient continues to urinate, after the middle section of urine is discharged, the seat body switch is switched on, the third electric telescopic rod works, the sealing plate seals the diversion trench, and the tail section of urine flows on the sealing plate; meanwhile, when the liquid level in the liquid receiving cup reaches a set value of the liquid level, the liquid level sensor transmits a signal to the programmable controller, and the driving motor works to drive the conveying belt to move, so that the liquid receiving cup is positioned at the lower part of the injector;
4) the electric push rod works to drive the piston rod to move downwards, so that the test solution is dripped into the solution receiving cup, and when the added test solution meets the requirement, the electric push rod stops working; observing the color of the precipitate;
5) after the color of the precipitate is observed, the driving motor continues to work to drive the liquid receiving cup to rotate downwards, the reaction liquid is poured into the filtering tank, and when the liquid receiving cup continues to move and contact the stop lever, the liquid receiving cup does not contact the magnet block and falls into the recovery tank;
6) first electric telescopic handle and second electric telescopic handle all contract, and drain hole and drip hole are all opened, press the mechanism button of washing by water, wash by water under the effect of gravity with the closing plate buckling, third electric telescopic handle work, pull back the closing plate a bit, with the diversion trench in the urine wash clean back, air-blower and heating wire work are dried with the moisture in the diversion trench.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810169984.4A CN108414511B (en) | 2018-03-01 | 2018-03-01 | Tumor urine detection device and method |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810169984.4A CN108414511B (en) | 2018-03-01 | 2018-03-01 | Tumor urine detection device and method |
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| CN108414511A CN108414511A (en) | 2018-08-17 |
| CN108414511B true CN108414511B (en) | 2020-06-02 |
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| CN109580599B (en) * | 2018-11-22 | 2021-06-04 | 鲁东大学 | Aquatic product culture environment measurement and control system and method for Internet of things |
| CN109581534B (en) * | 2018-12-06 | 2020-09-01 | 广东吉米有品智能科技有限公司 | Water-free detection method for cup |
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| EP0346083A2 (en) * | 1988-06-09 | 1989-12-13 | Inax Corporation | Apparatus for detecting ingredient in urine, and a toilet stool equipped with a urine detecting device |
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| CN204023746U (en) * | 2014-06-16 | 2014-12-17 | 孟州贝氏医疗器械有限公司 | Automatic collection urine and the toilet detected |
| CN205317536U (en) * | 2016-01-05 | 2016-06-15 | 王侃 | Urine ware is adopted in clinical laboratory's special use |
| CN205879610U (en) * | 2016-07-29 | 2017-01-11 | 白银市第一人民医院 | Midstream urine collection system |
| CN206609792U (en) * | 2017-09-21 | 2017-11-03 | 广州康琼医疗器械有限公司 | A kind of full automatic urine analyzer |
| CN206681104U (en) * | 2016-10-09 | 2017-11-28 | 广东欧陆卫浴有限公司 | A kind of intelligent water toilet pan with full-automatic sanitary equipment |
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- 2018-03-01 CN CN201810169984.4A patent/CN108414511B/en not_active Expired - Fee Related
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0346083A2 (en) * | 1988-06-09 | 1989-12-13 | Inax Corporation | Apparatus for detecting ingredient in urine, and a toilet stool equipped with a urine detecting device |
| CN101162188A (en) * | 2006-10-11 | 2008-04-16 | 上海市宝山区青少年科学技术指导站 | Urine collector |
| CN204023746U (en) * | 2014-06-16 | 2014-12-17 | 孟州贝氏医疗器械有限公司 | Automatic collection urine and the toilet detected |
| CN205317536U (en) * | 2016-01-05 | 2016-06-15 | 王侃 | Urine ware is adopted in clinical laboratory's special use |
| CN205879610U (en) * | 2016-07-29 | 2017-01-11 | 白银市第一人民医院 | Midstream urine collection system |
| CN206681104U (en) * | 2016-10-09 | 2017-11-28 | 广东欧陆卫浴有限公司 | A kind of intelligent water toilet pan with full-automatic sanitary equipment |
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