CN108413082B - Quick connector of micro-fluidic system - Google Patents
Quick connector of micro-fluidic system Download PDFInfo
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- CN108413082B CN108413082B CN201810309668.2A CN201810309668A CN108413082B CN 108413082 B CN108413082 B CN 108413082B CN 201810309668 A CN201810309668 A CN 201810309668A CN 108413082 B CN108413082 B CN 108413082B
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- way valve
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K15/00—Check valves
- F16K15/02—Check valves with guided rigid valve members
- F16K15/04—Check valves with guided rigid valve members shaped as balls
- F16K15/044—Check valves with guided rigid valve members shaped as balls spring-loaded
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- General Engineering & Computer Science (AREA)
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- Quick-Acting Or Multi-Walled Pipe Joints (AREA)
Abstract
A quick joint of a micro-fluidic system relates to a connecting device of the micro-fluidic system. The invention aims to solve the technical problems that the existing microfluidic device is difficult to realize automatic connection with an external pipeline interface, low in connection precision, long in required time, easy to leak and easy to generate cross contamination among liquids. The invention is composed of a one-way valve, a compression clamp, a sealing ring and a switch rod; one end of the switch rod is fixed on the spherical valve core through the outlet of the one-way valve, and the sealing ring is sleeved on the outer wall of the outlet of the one-way valve; the compressing clamp is clamped on the outer wall of the outlet of the one-way valve, the compressing clamp is in close contact with the sealing ring, and the compressing clamp is closer to the spherical valve core than the sealing ring. The quick joint structure of the microfluidic system is simple and convenient to manufacture and use, is connected with the inlet of the microfluidic channel in a compression joint mode and is automatically opened or closed without rotating or inserting for connection.
Description
Technical Field
The invention relates to a quick connector of a microfluidic system, belonging to the technical field of microfluidics.
Background
The micro-fluidic system is widely applied to the occasions of micro-drug injection, micro-fluidic chips, micro-water supply and drug delivery, micro-fluid analysis, micro-sample introduction in biomedical analysis and the like. In the application process, it is often necessary to quickly and efficiently inject the liquid sample or reaction solution, cleaning solution, etc. into the microfluidic device through the external pipeline. The prior connecting interface mainly adopts a steel pipe or a joint to be manually inserted and connected or rotationally connected with a substrate flow channel inlet of the microfluidic device made of materials such as PDMS or PMMA, and the like, so that the required time is long, the connecting precision is low, and the automatic connection is difficult to realize. The existing crimping type joint does not belong to a quick change-over joint, so when the joint is disconnected, reagents are easy to leak, and cross contamination among liquids is caused. With the improvement of the automation degree of the microfluidic system, the automatic connection and separation of the microfluidic device and the external pipeline become more and more urgent key problems to be solved.
Disclosure of Invention
The invention provides a quick connector of a micro-fluidic system, aiming at solving the technical problems that the existing micro-fluidic device is difficult to realize automatic connection with an external pipeline interface, has low connection precision, long required time, is easy to leak and is easy to generate cross contamination among liquids.
The quick joint of the micro-fluidic system consists of a one-way valve, a compression clamp 4, a sealing ring 5 and a switch rod 6;
the one-way valve consists of a valve body 1, a spring 2 and a spherical valve core 3;
the two ends of the valve body 1 are respectively an inlet 1-1 and an outlet 1-2 of the one-way valve, and the diameters of the inlet 1-1 and the outlet 1-2 of the one-way valve are smaller than that of the middle part;
the ball-shaped valve core 3 is arranged in the middle of the valve body 1 and close to the outlet 1-2 of the one-way valve, the spring 2 is arranged in the middle of the valve body 1 and close to the inlet 1-1 of the one-way valve, the spring 2 is in a compressed state, and two ends of the spring 2 respectively press the ball-shaped valve core 3 and the inlet 1-1 of the one-way valve;
one end of a switch rod 6 is fixed on the spherical valve core 3 through an outlet 1-2 of the one-way valve, a sealing ring 5 is sleeved on the outer wall of the outlet 1-2 of the one-way valve, and one end of the sealing ring 5 is flush with the outer end face of the outlet 1-2 of the one-way valve; the compressing clamp 4 is clamped on the outer wall of the outlet 1-2 of the one-way valve, the compressing clamp 4 is in close contact with the sealing ring 5, and the compressing clamp 4 is closer to the spherical valve core 3 than the sealing ring 5.
The application method and the principle of the quick connector of the microfluidic system are as follows:
firstly, connecting: the outlet 1-2 of the one-way valve of the quick connector of the microfluidic system is vertically downwards aligned to the inlet of a flow channel of the base of the microfluidic device, the free end of the switch rod 6 is contacted with the bottom surface of the base of the microfluidic device, a downward external force is applied to the pressing clamp 4, the lower end surface of the sealing ring 5 is tightly pressed on the upper surface of the base of the microfluidic device and is sealed with the upper surface of the microfluidic device, and the free end of the switch rod 6 further pushes open the spherical valve core 3 in the one-way valve due to the thrust of the base surface of the microfluidic device so that the one-way valve is in a communicated state, the communication between the microfluidic system and a liquid flow channel of an external connecting pipeline is realized;
II, disengaging: the external force for pressing the pressing clamp 4 downwards is removed, the quick connector of the microfluidic system leaves the substrate of the microfluidic device, the spherical valve core 3 of the one-way valve in the quick connector closes the valve port again under the action of the spring 2, the disconnection and the closing of a pipeline are ensured, and the cross contamination caused by the backflow of liquid in the microfluidic device is prevented;
and thirdly, only the first process and the second process need to be circulated when the composite material is repeatedly used.
The invention has the advantages that:
the quick connector of the microfluidic system can solve the problems that the existing microfluidic device is difficult to realize automatic connection with an external pipeline interface, the connection precision is low, the required time is long, the leakage is easy, the cross contamination among liquids is easy to generate and the like, and has the advantages of simple structure, convenience in manufacture and use, quick and efficient connection and disconnection, and the working efficiency is improved by 50%. The micro-channel inlet is connected with the micro-channel inlet in a compression joint mode and is automatically opened or closed without plug-in connection or rotary connection.
Drawings
FIG. 1 is a schematic diagram of a quick connector of a microfluidic system according to a first embodiment;
FIG. 2 is a schematic diagram of a first embodiment of a quick connector of a microfluidic system;
fig. 3 is a schematic view of a check valve according to a first embodiment.
Detailed Description
The first embodiment is as follows: the embodiment is a quick connector of a microfluidic system, as shown in fig. 1-3, and specifically comprises a one-way valve, a compression clamp 4, a sealing ring 5 and a switch rod 6;
the one-way valve consists of a valve body 1, a spring 2 and a spherical valve core 3;
the two ends of the valve body 1 are respectively an inlet 1-1 and an outlet 1-2 of the one-way valve, and the diameters of the inlet 1-1 and the outlet 1-2 of the one-way valve are smaller than that of the middle part;
the ball-shaped valve core 3 is arranged in the middle of the valve body 1 and close to the outlet 1-2 of the one-way valve, the spring 2 is arranged in the middle of the valve body 1 and close to the inlet 1-1 of the one-way valve, the spring 2 is in a compressed state, and two ends of the spring 2 respectively press the ball-shaped valve core 3 and the inlet 1-1 of the one-way valve;
one end of a switch rod 6 is fixed on the spherical valve core 3 through an outlet 1-2 of the one-way valve, a sealing ring 5 is sleeved on the outer wall of the outlet 1-2 of the one-way valve, and one end of the sealing ring 5 is flush with the outer end face of the outlet 1-2 of the one-way valve; the compressing clamp 4 is clamped on the outer wall of the outlet 1-2 of the one-way valve, the compressing clamp 4 is in close contact with the sealing ring 5, and the compressing clamp 4 is closer to the spherical valve core 3 than the sealing ring 5.
The application method and the principle of the quick connector of the micro-fluidic system of the embodiment are as follows:
firstly, connecting: the outlet 1-2 of the one-way valve of the quick connector of the microfluidic system is vertically downwards aligned to the inlet of a flow channel of the base of the microfluidic device, the free end of the switch rod 6 is contacted with the bottom surface of the base of the microfluidic device, a downward external force is applied to the pressing clamp 4, the lower end surface of the sealing ring 5 is tightly pressed on the upper surface of the base of the microfluidic device and is sealed with the upper surface of the microfluidic device, and the free end of the switch rod 6 further pushes open the spherical valve core 3 in the one-way valve due to the thrust of the base surface of the microfluidic device so that the one-way valve is in a communicated state, the communication between the microfluidic system and a liquid flow channel of an external connecting pipeline is realized;
II, disengaging: the external force for pressing the pressing clamp 4 downwards is removed, the quick connector of the microfluidic system leaves the substrate of the microfluidic device, the spherical valve core 3 of the one-way valve in the quick connector closes the valve port again under the action of the spring 2, the disconnection and the closing of a pipeline are ensured, and the cross contamination caused by the backflow of liquid in the microfluidic device is prevented;
and thirdly, only the first process and the second process need to be circulated when the composite material is repeatedly used.
The advantages of this embodiment:
the quick connector of the micro-fluidic system can solve the problems that the existing micro-fluidic device is difficult to realize automatic connection with an external pipeline interface, the connection precision is low, the required time is long, the leakage is easy, the cross contamination among liquids is easy to generate and the like, the structure is simple, the manufacture and the use are convenient, the connection and the disconnection are quick and efficient, and the working efficiency is improved by 50%. The micro-channel inlet is connected with the micro-channel inlet in a compression joint mode and is automatically opened or closed without plug-in connection or rotary connection.
The second embodiment is as follows: the first difference between the present embodiment and the specific embodiment is: the material of the compressing clamp 4 is stainless steel or plastic. The rest is the same as the first embodiment.
The third concrete implementation mode: the present embodiment differs from the first or second embodiment in that: the sealing ring 5 is made of rubber. The others are the same as in the first or second embodiment.
The fourth concrete implementation mode: the difference between this embodiment mode and one of the first to third embodiment modes is: the switch rod 6 is made of stainless steel or plastic. The rest is the same as one of the first to third embodiments.
The fifth concrete implementation mode: the difference between this embodiment and one of the first to fourth embodiments is: the valve body 1 is made of metal or nonmetal. The rest is the same as one of the first to fourth embodiments.
The invention was verified with the following tests:
test one: the test is a quick joint of a microfluidic system, and as shown in fig. 1-3, the quick joint specifically comprises a one-way valve, a compression clamp 4, a sealing ring 5 and a switch rod 6;
the one-way valve consists of a valve body 1, a spring 2 and a spherical valve core 3;
the two ends of the valve body 1 are respectively an inlet 1-1 and an outlet 1-2 of the one-way valve, and the diameters of the inlet 1-1 and the outlet 1-2 of the one-way valve are smaller than that of the middle part;
the ball-shaped valve core 3 is arranged in the middle of the valve body 1 and close to the outlet 1-2 of the one-way valve, the spring 2 is arranged in the middle of the valve body 1 and close to the inlet 1-1 of the one-way valve, the spring 2 is in a compressed state, and two ends of the spring 2 respectively press the ball-shaped valve core 3 and the inlet 1-1 of the one-way valve;
one end of a switch rod 6 is fixed on the spherical valve core 3 through an outlet 1-2 of the one-way valve, a sealing ring 5 is sleeved on the outer wall of the outlet 1-2 of the one-way valve, and one end of the sealing ring 5 is flush with the outer end face of the outlet 1-2 of the one-way valve; the compression clamp 4 is clamped on the outer wall of the outlet 1-2 of the one-way valve, the compression clamp 4 is tightly contacted with the sealing ring 5, and the compression clamp 4 is closer to the spherical valve core 3 than the sealing ring 5;
the material of the pressing clamp 4 is stainless steel;
the sealing ring 5 is made of rubber;
the switch rod 6 is made of stainless steel;
the valve body 1 is made of metal.
The application method and the principle of the quick connector of the test micro-fluidic system are as follows:
firstly, connecting: the outlet 1-2 of the one-way valve of the quick connector of the microfluidic system is vertically downwards aligned to the inlet of a flow channel of the base of the microfluidic device, the free end of the switch rod 6 is contacted with the bottom surface of the base of the microfluidic device, a downward external force is applied to the pressing clamp 4, the lower end surface of the sealing ring 5 is tightly pressed on the upper surface of the base of the microfluidic device and is sealed with the upper surface of the microfluidic device, and the free end of the switch rod 6 further pushes open the spherical valve core 3 in the one-way valve due to the thrust of the base surface of the microfluidic device so that the one-way valve is in a communicated state, the communication between the microfluidic system and a liquid flow channel of an external connecting pipeline is realized;
II, disengaging: the external force for pressing the pressing clamp 4 downwards is removed, the quick connector of the microfluidic system leaves the substrate of the microfluidic device, the spherical valve core 3 of the one-way valve in the quick connector closes the valve port again under the action of the spring 2, the disconnection and the closing of a pipeline are ensured, and the cross contamination caused by the backflow of liquid in the microfluidic device is prevented;
and thirdly, only the first process and the second process need to be circulated when the composite material is repeatedly used.
The advantages of this test:
the micro-fluidic system quick connector can solve the problems that the existing micro-fluidic device is difficult to realize automatic connection with an external pipeline interface, the connection precision is low, the required time is long, the leakage is easy, the cross contamination among liquids is easy to generate, and the like, has a simple structure, is convenient to manufacture and use, is quick and efficient to connect and disconnect, and improves the working efficiency by 50%. The micro-channel inlet is connected with the micro-channel inlet in a compression joint mode and is automatically opened or closed without plug-in connection or rotary connection.
Claims (5)
1. A quick joint of a micro-fluidic system is characterized in that the quick joint of the micro-fluidic system consists of a one-way valve, a compression clamp (4), a sealing ring (5) and a switch rod (6);
the one-way valve consists of a valve body (1), a spring (2) and a spherical valve core (3);
the two ends of the valve body (1) are respectively an inlet (1-1) and an outlet (1-2) of the one-way valve, and the diameters of the inlet (1-1) and the outlet (1-2) of the one-way valve are smaller than that of the middle part;
the ball-shaped valve core (3) is arranged in the middle of the valve body (1) and close to an outlet (1-2) of the one-way valve, the spring (2) is arranged in the middle of the valve body (1) and close to an inlet (1-1) of the one-way valve, the spring (2) is in a compression state, and two ends of the spring (2) respectively press the ball-shaped valve core (3) and the inlet (1-1) of the one-way valve;
one end of the switch rod (6) is fixed on the spherical valve core (3) through an outlet (1-2) of the one-way valve, the sealing ring (5) is sleeved on the outer wall of the outlet (1-2) of the one-way valve, and one end of the sealing ring (5) is flush with the outer end face of the outlet (1-2) of the one-way valve; the compressing clamp (4) is clamped on the outer wall of the outlet (1-2) of the one-way valve, the compressing clamp (4) is in close contact with the sealing ring (5), and the compressing clamp (4) is closer to the spherical valve core (3) than the sealing ring (5).
2. The quick coupling for microfluidic systems according to claim 1, wherein the compressing clip (4) is made of stainless steel or plastic.
3. The quick coupling for microfluidic systems according to claim 1, wherein the sealing ring (5) is made of rubber.
4. The quick connector of a microfluidic system according to claim 1, wherein the switch lever (6) is made of stainless steel or plastic.
5. The quick coupling for microfluidic systems according to claim 1, wherein the valve body (1) is made of metal or nonmetal.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810309668.2A CN108413082B (en) | 2018-04-08 | 2018-04-08 | Quick connector of micro-fluidic system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810309668.2A CN108413082B (en) | 2018-04-08 | 2018-04-08 | Quick connector of micro-fluidic system |
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| Publication Number | Publication Date |
|---|---|
| CN108413082A CN108413082A (en) | 2018-08-17 |
| CN108413082B true CN108413082B (en) | 2020-01-14 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810309668.2A Active CN108413082B (en) | 2018-04-08 | 2018-04-08 | Quick connector of micro-fluidic system |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111149558B (en) * | 2020-01-07 | 2021-09-24 | 深圳市现代城市建筑设计有限公司 | Greening roof structure |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5048578A (en) * | 1990-03-01 | 1991-09-17 | Arkady Dorf | Oil drainage coupler |
| CN201215206Y (en) * | 2008-06-18 | 2009-04-01 | 冯建洪 | Air throttle for independent air blast rearing cage |
| CN202629095U (en) * | 2012-06-11 | 2012-12-26 | 重庆瑞信气体有限公司 | Automatic blocking inflation valve |
| CN203036136U (en) * | 2012-11-29 | 2013-07-03 | 海盐管件制造有限公司 | High pressure detachable type ball sealing pressure measuring connector |
| CN104455578A (en) * | 2014-10-30 | 2015-03-25 | 中国五洲工程设计集团有限公司 | Bidirectional valve with flow adjustable in one direction |
| CN106621026A (en) * | 2016-12-29 | 2017-05-10 | 四川南格尔生物科技有限公司 | Non-return needle connector |
-
2018
- 2018-04-08 CN CN201810309668.2A patent/CN108413082B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5048578A (en) * | 1990-03-01 | 1991-09-17 | Arkady Dorf | Oil drainage coupler |
| CN201215206Y (en) * | 2008-06-18 | 2009-04-01 | 冯建洪 | Air throttle for independent air blast rearing cage |
| CN202629095U (en) * | 2012-06-11 | 2012-12-26 | 重庆瑞信气体有限公司 | Automatic blocking inflation valve |
| CN203036136U (en) * | 2012-11-29 | 2013-07-03 | 海盐管件制造有限公司 | High pressure detachable type ball sealing pressure measuring connector |
| CN104455578A (en) * | 2014-10-30 | 2015-03-25 | 中国五洲工程设计集团有限公司 | Bidirectional valve with flow adjustable in one direction |
| CN106621026A (en) * | 2016-12-29 | 2017-05-10 | 四川南格尔生物科技有限公司 | Non-return needle connector |
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| CN108413082A (en) | 2018-08-17 |
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