CN108413082A - A kind of quick coupling of microfluidic system - Google Patents
A kind of quick coupling of microfluidic system Download PDFInfo
- Publication number
- CN108413082A CN108413082A CN201810309668.2A CN201810309668A CN108413082A CN 108413082 A CN108413082 A CN 108413082A CN 201810309668 A CN201810309668 A CN 201810309668A CN 108413082 A CN108413082 A CN 108413082A
- Authority
- CN
- China
- Prior art keywords
- check valve
- microfluidic system
- sealing ring
- outlet
- quick coupling
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K15/00—Check valves
- F16K15/02—Check valves with guided rigid valve members
- F16K15/04—Check valves with guided rigid valve members shaped as balls
- F16K15/044—Check valves with guided rigid valve members shaped as balls spring-loaded
Landscapes
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Quick-Acting Or Multi-Walled Pipe Joints (AREA)
Abstract
A kind of quick coupling of microfluidic system is related to a kind of attachment device of microfluidic system.It is difficult to realize to connect automatically the present invention is to solve existing micro fluidic device and exterior line interface, connection precision is low, required time is long, be easy leakage, easy tos produce the technical issues of cross contamination between liquid.The present invention is made of check valve, pressing clip, sealing ring and switch lever；One end of switch lever is fixed on by the outlet of check valve on spherical valve core, and sealing ring is sleeved on the outlet outer wall of check valve；Pressing clip is clipped in the outlet outer wall of check valve, and pressing clip and sealing ring are in close contact, and pressing clip compares sealing ring closer to spherical valve core.The quick coupling structure of microfluidic system of the present invention is simply convenient for making and using, and is connect and is automatically opened or closed with fluid channel import by the way of crimping, without rotation or is inserted into connection.
Description
Technical field
The present invention relates to a kind of quick couplings of microfluidic system, belong to microfluidic art.
Background technology
Microfluidic system is widely used in trace drug injection, micro-fluidic chip, micro water supply administration, micro fluid analysis
And the occasions such as micro-sampling in bio-medical analysis.It is usually needed in application process by institute's fluid sample or reaction solution, clear
Washing lotion etc. quickly and efficiently injects micro fluidic device by exterior line.Current connecting interface mainly use steel pipe or connector with
The micro fluidic device substrate flow channel entry point that the materials such as PDMS or PMMA make carries out being manually inserted into connection or rotatable connection, is taken
Between long and connection precision it is low, it is difficult to realize automatic connection.Current crimped end-fitting is connecing due to being not belonging to quick changing-over connector
When head disengages, reagent is easy leakage, leads to cross contamination between liquid.With the raising of microfluidic system the degree of automation, miniflow
Control device and the automatic of exterior line connect and are separated into the more and more anxious critical issue waited in solution.
Invention content
The present invention is to solve existing micro fluidic devices to be difficult to realize to connect automatically with exterior line interface, connection precision
It is low, required time is long, is easy leakage, easy tos produce the technical issues of cross contamination between liquid, and provide a kind of microfluidic system
Quick coupling.
A kind of quick coupling of microfluidic system of the present invention is by 6 groups of check valve, pressing clip 4, sealing ring 5 and switch lever
At；
The check valve is made of valve body 1, spring 2 and spherical valve core 3；
The both ends of the valve body 1 are respectively import 1-1 and outlet 1-2, the import 1-1 of check valve and the outlet of check valve
The diameter of 1-2 is respectively less than the diameter of middle section；
The inside in 1 middle section of valve body and the outlet 1-2 close to check valve is arranged in spherical valve core 3, and spring 2 is arranged in valve
The import 1-1 of the inside of 1 middle section of body and close check valve, spring 2 are in compressive state, and the both ends of spring 2 are pressed respectively
The import 1-1 of spherical valve core 3 and check valve；
One end of switch lever 6 is fixed on by the outlet 1-2 of check valve on spherical valve core 3, and sealing ring 5 is sleeved on check valve
The outer wall of 1-2 is exported, and one end of sealing ring 5 is concordant with the outlet outer end face of 1-2 of check valve；Pressing clip 4 is clipped in check valve
Outlet 1-2 outer walls, pressing clip 4 and sealing ring 5 be in close contact, and pressing clip 4 compared to sealing ring 5 closer to spherical valve core 3.
The application method and principle of microfluidic system quick coupling of the present invention be：
One, it connects：The one-way valved outlet 1-2 of microfluidic system quick coupling of the present invention is directed at micro-fluidic dress straight down
The flow channel entry point of substrate is set, and the free end of switch lever 6 is made to touch the bottom surface of micro fluidic device substrate, pressing clip 4 is applied
Downward external force so that the lower face of sealing ring 5 is pressed on the upper surface of micro fluidic device substrate and upper with micro fluidic device
Face seal, the free end of switch lever 6 is due in the thrust by micro fluidic device basal surface further open-top check valve at this time
Spherical valve core 3 so that check valve is in connected state, realize the connection of microfluidic system and external connection pipeline flow channel for liquids, it is complete
It is acted at piping connection；
Two, it disengages：The external force compressed downwards to pressing clip 4 is removed, micro-fluidic dress is left in the quick coupling of microfluidic system
Substrate is set, the spherical valve core 3 of quick coupling internal one-way valve is re-closing off valve port under the effect of spring 2, ensure that pipeline
Disengagement and closure, and prevent micro fluidic device internal liquid flow backwards and generate cross contamination；
Cyclic process one, process two are only needed when three, reusing.
Advantages of the present invention：
Microfluidic system quick coupling of the present invention can solve existing micro fluidic device and exterior line interface
It being difficult to realize connect automatically, connection precision is low, and required time is grown, the problems such as being easy leakage, easy to produce cross contamination between liquid,
And it is simple in structure convenient for making and using, rapidly and efficiently, working efficiency improves 50% for connection and disengagement.By the way of crimping with
Fluid channel import is connected and is automatically opened or closed, and is connected or is rotatably connected without plug-in type.
Description of the drawings
Fig. 1 is the quick coupling schematic diagram of the microfluidic system of specific implementation mode one；
Schematic diagram when Fig. 2 is the quick coupling work of the microfluidic system of specific implementation mode one；
Fig. 3 is the check valve schematic diagram of specific implementation mode one.
Specific implementation mode
Specific implementation mode one：Present embodiment is a kind of quick coupling of microfluidic system, such as Fig. 1-Fig. 3, specifically
It is made of check valve, pressing clip 4, sealing ring 5 and switch lever 6；
The check valve is made of valve body 1, spring 2 and spherical valve core 3；
The both ends of the valve body 1 are respectively import 1-1 and outlet 1-2, the import 1-1 of check valve and the outlet of check valve
The diameter of 1-2 is respectively less than the diameter of middle section；
The inside in 1 middle section of valve body and the outlet 1-2 close to check valve is arranged in spherical valve core 3, and spring 2 is arranged in valve
The import 1-1 of the inside of 1 middle section of body and close check valve, spring 2 are in compressive state, and the both ends of spring 2 are pressed respectively
The import 1-1 of spherical valve core 3 and check valve；
One end of switch lever 6 is fixed on by the outlet 1-2 of check valve on spherical valve core 3, and sealing ring 5 is sleeved on check valve
The outer wall of 1-2 is exported, and one end of sealing ring 5 is concordant with the outlet outer end face of 1-2 of check valve；Pressing clip 4 is clipped in check valve
Outlet 1-2 outer walls, pressing clip 4 and sealing ring 5 be in close contact, and pressing clip 4 compared to sealing ring 5 closer to spherical valve core 3.
The application method and principle of present embodiment microfluidic system quick coupling be：
One, it connects：The one-way valved outlet 1-2 of microfluidic system quick coupling of the present invention is directed at micro-fluidic dress straight down
The flow channel entry point of substrate is set, and the free end of switch lever 6 is made to touch the bottom surface of micro fluidic device substrate, pressing clip 4 is applied
Downward external force so that the lower face of sealing ring 5 is pressed on the upper surface of micro fluidic device substrate and upper with micro fluidic device
Face seal, the free end of switch lever 6 is due in the thrust by micro fluidic device basal surface further open-top check valve at this time
Spherical valve core 3 so that check valve is in connected state, realize the connection of microfluidic system and external connection pipeline flow channel for liquids, it is complete
It is acted at piping connection；
Two, it disengages：The external force compressed downwards to pressing clip 4 is removed, micro-fluidic dress is left in the quick coupling of microfluidic system
Substrate is set, the spherical valve core 3 of quick coupling internal one-way valve is re-closing off valve port under the effect of spring 2, ensure that pipeline
Disengagement and closure, and prevent micro fluidic device internal liquid flow backwards and generate cross contamination；
Cyclic process one, process two are only needed when three, reusing.
The advantages of present embodiment：
Microfluidic system quick coupling described in present embodiment can solve existing micro fluidic device and exterior line
Interface is difficult to realize connect automatically, and connection precision is low, and required time is grown, and is easy leakage, easy tos produce cross contamination etc. between liquid
Problem, and it is simple in structure convenient for making and using, rapidly and efficiently, working efficiency improves 50% for connection and disengagement.Using crimping
Mode connect and is automatically opened or closed with fluid channel import, connects or is rotatably connected without plug-in type.
Specific implementation mode two：The present embodiment is different from the first embodiment in that：The material of the pressing clip 4
For stainless steel or plastics.Other are same as the specific embodiment one.
Specific implementation mode three：The present embodiment is different from the first and the second embodiment in that：The sealing ring 5
Material is rubber.Other are the same as one or two specific embodiments.
Specific implementation mode four：Unlike one of present embodiment and specific implementation mode one to three：The switch
The material of bar 6 is stainless steel or plastics.Other are identical as one of specific implementation mode one to three.
Specific implementation mode five：Unlike one of present embodiment and specific implementation mode one to four：The valve body 1
Material be metal or nonmetallic.Other are identical as one of specific implementation mode one to four.
The present invention is verified with following tests：
Experiment one：This experiment is a kind of quick coupling of microfluidic system, such as Fig. 1-Fig. 3, specifically by check valve, compress
Folder 4, sealing ring 5 and switch lever 6 form；
The check valve is made of valve body 1, spring 2 and spherical valve core 3；
The both ends of the valve body 1 are respectively import 1-1 and outlet 1-2, the import 1-1 of check valve and the outlet of check valve
The diameter of 1-2 is respectively less than the diameter of middle section；
The inside in 1 middle section of valve body and the outlet 1-2 close to check valve is arranged in spherical valve core 3, and spring 2 is arranged in valve
The import 1-1 of the inside of 1 middle section of body and close check valve, spring 2 are in compressive state, and the both ends of spring 2 are pressed respectively
The import 1-1 of spherical valve core 3 and check valve；
One end of switch lever 6 is fixed on by the outlet 1-2 of check valve on spherical valve core 3, and sealing ring 5 is sleeved on check valve
The outer wall of 1-2 is exported, and one end of sealing ring 5 is concordant with the outlet outer end face of 1-2 of check valve；Pressing clip 4 is clipped in check valve
Outlet 1-2 outer walls, pressing clip 4 and sealing ring 5 be in close contact, and pressing clip 4 compared to sealing ring 5 closer to spherical valve core 3；
The material of the pressing clip 4 is stainless steel；
The material of the sealing ring 5 is rubber；
The material of the switch lever 6 is stainless steel；
The material of the valve body 1 is metal.
The application method and principle of this experiment microfluidic system quick coupling be：
One, it connects：The one-way valved outlet 1-2 of microfluidic system quick coupling of the present invention is directed at micro-fluidic dress straight down
The flow channel entry point of substrate is set, and the free end of switch lever 6 is made to touch the bottom surface of micro fluidic device substrate, pressing clip 4 is applied
Downward external force so that the lower face of sealing ring 5 is pressed on the upper surface of micro fluidic device substrate and upper with micro fluidic device
Face seal, the free end of switch lever 6 is due in the thrust by micro fluidic device basal surface further open-top check valve at this time
Spherical valve core 3 so that check valve is in connected state, realize the connection of microfluidic system and external connection pipeline flow channel for liquids, it is complete
It is acted at piping connection；
Two, it disengages：The external force compressed downwards to pressing clip 4 is removed, micro-fluidic dress is left in the quick coupling of microfluidic system
Substrate is set, the spherical valve core 3 of quick coupling internal one-way valve is re-closing off valve port under the effect of spring 2, ensure that pipeline
Disengagement and closure, and prevent micro fluidic device internal liquid flow backwards and generate cross contamination；
Cyclic process one, process two are only needed when three, reusing.
The advantages of this experiment：
This experiment microfluidic system quick coupling can solve existing micro fluidic device and exterior line interface
It being difficult to realize connect automatically, connection precision is low, and required time is grown, the problems such as being easy leakage, easy to produce cross contamination between liquid,
And it is simple in structure convenient for making and using, rapidly and efficiently, working efficiency improves 50% for connection and disengagement.By the way of crimping with
Fluid channel import is connected and is automatically opened or closed, and is connected or is rotatably connected without plug-in type.
Claims (5)
1. a kind of quick coupling of microfluidic system, it is characterised in that the quick coupling of microfluidic system is by check valve, compresses
Press from both sides (4), sealing ring (5) and switch lever (6) composition；
The check valve is made of valve body (1), spring (2) and spherical valve core (3)；
The both ends of the valve body (1) be respectively check valve import (1-1) and outlet (1-2), the import (1-1) of check valve and
The diameter of outlet (1-2) is respectively less than the diameter of middle section；
The inside in valve body (1) middle section and the outlet (1-2) close to check valve, spring (2) setting is arranged in spherical valve core (3)
Inside in valve body (1) middle section and the import (1-1) close to check valve, spring (2) are in compressive state, spring (2)
Both ends pressed against the import (1-1) of spherical valve core (3) and check valve respectively；
One end of switch lever (6) is fixed on by the outlet (1-2) of check valve on spherical valve core (3), and sealing ring (5) is sleeved on unidirectionally
The outer wall of the outlet (1-2) of valve, and one end of sealing ring (5) is concordant with the outer end face of outlet (1-2) of check valve；Pressing clip
(4) it is clipped in outlet (1-2) outer wall of check valve, pressing clip (4) and sealing ring (5) are in close contact, and pressing clip (4) is compared to sealing
(5) are enclosed closer to spherical valve core (3).
2. a kind of quick coupling of microfluidic system according to claim 1, it is characterised in that the pressing clip (4)
Material is stainless steel or plastics.
3. a kind of quick coupling of microfluidic system according to claim 1, it is characterised in that the sealing ring (5)
Material is rubber.
4. a kind of quick coupling of microfluidic system according to claim 1, it is characterised in that the switch lever (6)
Material is stainless steel or plastics.
5. a kind of quick coupling of microfluidic system according to claim 1, it is characterised in that the material of the valve body (1)
Matter is metal or nonmetallic.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810309668.2A CN108413082B (en) | 2018-04-08 | 2018-04-08 | Quick connector of micro-fluidic system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810309668.2A CN108413082B (en) | 2018-04-08 | 2018-04-08 | Quick connector of micro-fluidic system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN108413082A true CN108413082A (en) | 2018-08-17 |
| CN108413082B CN108413082B (en) | 2020-01-14 |
Family
ID=63134731
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810309668.2A Active CN108413082B (en) | 2018-04-08 | 2018-04-08 | Quick connector of micro-fluidic system |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108413082B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111149558A (en) * | 2020-01-07 | 2020-05-15 | 深圳市现代城市建筑设计有限公司 | Greening roof structure |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5048578A (en) * | 1990-03-01 | 1991-09-17 | Arkady Dorf | Oil drainage coupler |
| CN201215206Y (en) * | 2008-06-18 | 2009-04-01 | 冯建洪 | Air throttle for independent air blast rearing cage |
| CN202629095U (en) * | 2012-06-11 | 2012-12-26 | 重庆瑞信气体有限公司 | Automatic blocking inflation valve |
| CN203036136U (en) * | 2012-11-29 | 2013-07-03 | 海盐管件制造有限公司 | High pressure detachable type ball sealing pressure measuring connector |
| CN104455578A (en) * | 2014-10-30 | 2015-03-25 | 中国五洲工程设计集团有限公司 | Bidirectional valve with flow adjustable in one direction |
| CN106621026A (en) * | 2016-12-29 | 2017-05-10 | 四川南格尔生物科技有限公司 | Non-return needle connector |
-
2018
- 2018-04-08 CN CN201810309668.2A patent/CN108413082B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5048578A (en) * | 1990-03-01 | 1991-09-17 | Arkady Dorf | Oil drainage coupler |
| CN201215206Y (en) * | 2008-06-18 | 2009-04-01 | 冯建洪 | Air throttle for independent air blast rearing cage |
| CN202629095U (en) * | 2012-06-11 | 2012-12-26 | 重庆瑞信气体有限公司 | Automatic blocking inflation valve |
| CN203036136U (en) * | 2012-11-29 | 2013-07-03 | 海盐管件制造有限公司 | High pressure detachable type ball sealing pressure measuring connector |
| CN104455578A (en) * | 2014-10-30 | 2015-03-25 | 中国五洲工程设计集团有限公司 | Bidirectional valve with flow adjustable in one direction |
| CN106621026A (en) * | 2016-12-29 | 2017-05-10 | 四川南格尔生物科技有限公司 | Non-return needle connector |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111149558A (en) * | 2020-01-07 | 2020-05-15 | 深圳市现代城市建筑设计有限公司 | Greening roof structure |
Also Published As
| Publication number | Publication date |
|---|---|
| CN108413082B (en) | 2020-01-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN204514801U (en) | A kind of throwing type micro-fluidic chip for residues of pesticides Site Detection | |
| CN108413081B (en) | A kind of forming method of miniature heat-shrink tube straight check valve | |
| CN108413082A (en) | A kind of quick coupling of microfluidic system | |
| CN108339578A (en) | Drop injector and use its drop sample injection method | |
| WO2010025284A3 (en) | Fluid-transfer collection assembly including breakable vial and method of using same | |
| CN204448044U (en) | The extraction of liquid and injection device in a kind of closed environment | |
| CN207101968U (en) | A kind of chromatography column apparatus of automatic liquid-feeding | |
| CN202182836U (en) | Gas sampling bag | |
| CN205182783U (en) | Micro -fluidic chip anchor clamps | |
| CN205361372U (en) | Reversible micro -fluidic chip anchor clamps | |
| CN107694651A (en) | Reversible micro-fluidic chip clamp | |
| CN107138193B (en) | Digital PCR instrument | |
| CN107702967B (en) | It is a kind of based on the space station of micro-fluidic chip cell sample automatic pretreatment apparatus | |
| WO2014015752A1 (en) | Specimen processing device | |
| CN105536904A (en) | Reversible micro fluidic chip clamp | |
| CN109453828A (en) | A kind of integrated micro-flow control chip equipment | |
| CN115386472A (en) | Micro-fluidic card box of nucleic acid detection card | |
| CN210142020U (en) | Steel cylinder sampler | |
| CN207866565U (en) | A kind of integrated quantitative sampling mix reagent device | |
| CN212441250U (en) | Switching device of micro-fluidic chip | |
| CN204330530U (en) | Be convenient to the capillary viscosimeter of liquid feeding and auxiliary heating | |
| CN218937866U (en) | Sampler capable of continuously sampling | |
| CN200960357Y (en) | Triplet rotary plug | |
| CN220559256U (en) | Quick connector of micro-fluidic chip | |
| CN215866607U (en) | Sample fluid control system of multi-channel micro-fluidic chip |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |