CN108404201A - A kind of anti-bacterial, anti-itching dressing and preparation method thereof containing tea oil - Google Patents

A kind of anti-bacterial, anti-itching dressing and preparation method thereof containing tea oil Download PDF

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Publication number
CN108404201A
CN108404201A CN201810391567.4A CN201810391567A CN108404201A CN 108404201 A CN108404201 A CN 108404201A CN 201810391567 A CN201810391567 A CN 201810391567A CN 108404201 A CN108404201 A CN 108404201A
Authority
CN
China
Prior art keywords
tea oil
itching
bacterial
dressing
gel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810391567.4A
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Chinese (zh)
Inventor
褚加冕
褚省吾
陈达永
张华泉
程文涵
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ROOSIN MEDICAL Co Ltd
Original Assignee
ROOSIN MEDICAL Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ROOSIN MEDICAL Co Ltd filed Critical ROOSIN MEDICAL Co Ltd
Priority to CN201810391567.4A priority Critical patent/CN108404201A/en
Publication of CN108404201A publication Critical patent/CN108404201A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061Use of materials characterised by their function or physical properties
    • A61L26/008Hydrogels or hydrocolloids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0014Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0023Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061Use of materials characterised by their function or physical properties
    • A61L26/0066Medicaments; Biocides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/30Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Materials Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)

Abstract

The anti-bacterial, anti-itching dressing containing tea oil that the invention discloses a kind of, is made of tea oil and gel-type vehicle;Wherein the content of tea oil is 0.1% 25%, and the content of gel-type vehicle is 75% 99.9%.The dressing is that the tea tree oil component of oiliness is added to be uniformly mixed in gel-type vehicle to form tea tree oleogel.The present invention, can be effectively antipruritic for the itch phenomenon in wound healing process;To because of the mishandling wound of wound itch, there is anti-infection effect, while it can avoid occurring the wound deterioration caused by itch is mishandling again.

Description

A kind of anti-bacterial, anti-itching dressing and preparation method thereof containing tea oil
Technical field
The invention belongs to medical dressing technical fields, and in particular to a kind of anti-bacterial, anti-itching dressing and its preparation containing tea oil Method.
Background technology
It is updated with the continuous development of medical technology, the increasingly raising of people's living standard, people are for wound care Demand is also higher and higher, injures epidermis wound below in the process of healing, it will usually the phenomenon that with itching, this be by It is broken in the nerve endings of skin, wound healing is filled by a kind of new tissue, and this new tissue is connective tissue. Newborn blood vessel and nerve will grow connective tissue.Newborn nerve endings is highly susceptible to stimulate, still due to function at this time It is incomplete, feel fuzzy, then generates gargalesthesia.And when wound is itched, it should not scratch, should not be with clothes friction, it should not be with heat Having one's hair waved bathes a wound, in order to avoid aggravate gargalesthesia or make wound infection, so that delaying wound healing.In this case, it is necessary to a kind of Dressing, can nuring wound and antipruritic and prevention infection.
On the market two classes, traditional dressing are broadly divided into currently used for the dressing of wound care(Mainly gauze)It is applied with high-end Material(Such as hydrogel, hydrocolloid, alginates), these traditional dressings be mainly used for wound covering and provide physical barriers;It is high End dressing belongs to moist dressing, and moistening healing environment can be provided for wound, promotes wound healing, or even have substantial portion of height End dressing has an antibacterial functions simultaneously, but these dressing do not have and provide antipruritic function in wound healing process.
Invention content
The present invention provides a kind of anti-bacterial, anti-itching dressing containing tea oil, solve the problems, such as wound itch in agglutination with And because wound itches mishandling, the problem of leading to wound infection.
In order to solve the above technical problems, the present invention adopts the following technical scheme that:A kind of anti-bacterial, anti-itching dressing containing tea oil, It is characterized in that:It is made of tea oil and gel-type vehicle;Wherein the content of tea oil is 0.1%-25%, and the content of gel-type vehicle is 75%-99.9%。
Further, content >=30% of Meng's alkene -1- alcohol in tea oil;
Further, the gel-type vehicle by following mass percent at being grouped as:Alcohol 1%-15%, thickener 0.1%-5%, Emulsifier 0.1%-5%, surplus are water.
Further, the alcohol one or more of is worked as by ethyl alcohol, ethylene glycol, propylene glycol, glycerine and is formed.
Further, the thickener by sodium carboxymethylcellulose, carbomer, Sodium Polyacrylate, sodium alginate in One or more compositions.
Further, the emulsifier is by emulsifier 343, Pemulen polymer, Biobase S, Delta emulsifiers One or more compositions in the middle.
The preparation method for the anti-bacterial, anti-itching dressing containing tea oil that the present invention also provides a kind of:The tea tree oil component of oiliness is added Enter to be uniformly mixed in gel-type vehicle and forms tea tree oleogel.
Beneficial effects of the present invention:
1, the antipruritic antibacterial dressing of the invention containing tea oil, can be effectively antipruritic for the itch phenomenon in wound healing process;
2, the antipruritic antibacterial dressing containing tea oil is to because of the mishandling wound of wound itch, having anti-infection effect, while can Avoid occurring the wound deterioration caused by itch is mishandling again.
Specific implementation mode
Technical scheme of the present invention will be clearly and completely described by specific implementation mode below.
Embodiment 1
It weighs 5g propylene glycol and 85g purifying water dissolutions is added, then weigh 5g sodium carboxymethylcelluloses and be added in solution and dissolve, then claim It takes 5gDelta emulsifiers to be added in above-mentioned solution to dissolve;It finally weighs 11.1g tea oils to be added in wound solution, uses breast Change equipment to be emulsified, the antipruritic antibacterial dressing containing tea oil to obtain the final product after complete tea oil gel pack sterilizing will be emulsified.
Embodiment 2
It weighs 10g ethyl alcohol and 86g purifying water dissolutions is added, then weigh 2g Sodium Polyacrylates and be added in solution and dissolve, then weigh 2g Pemulen polymer, which is added in above-mentioned solution, to be dissolved;It finally weighs 25g tea oils to be added in wound solution, be set using emulsification It is standby to be emulsified, the antipruritic antibacterial dressing containing tea oil to obtain the final product after complete tea oil gel pack sterilizing will be emulsified.
Embodiment 3
It weighs 15g glycerine and 75g purifying water dissolutions is added, then weigh 5g sodium alginates and be added in solution and dissolve, then weigh 5g Emulsifier 343, which is added in above-mentioned solution, to be dissolved;It finally weighs 13.63g tea oils to be added in wound solution, uses emulsifying device It is emulsified, the antipruritic antibacterial dressing containing tea oil to obtain the final product after complete tea oil gel pack sterilizing will be emulsified.
Embodiment 4
It weighs 8g ethylene glycol and 87g purifying water dissolutions is added, then weigh 2.5g carbomers and be added in solution and dissolve, then weigh 2g Biobase S, which are added in above-mentioned solution, to be dissolved;It finally weighs 5.26g tea oils to be added in wound solution, uses emulsifying device It is emulsified, the antipruritic antibacterial dressing containing tea oil to obtain the final product after complete tea oil gel pack sterilizing will be emulsified.
The tea oil of Ben Aming is played a role in the form of a kind of Membrane destructive agent, by destroying membrane structure, makes potassium in bacterium Ion-leakage inhibits bacterial respiratory, stimulates bacterium self-dissolving, and electron density in bacterium is caused to be lost, to change cytomorphology, Play antibacterial action;Tea oil has strong permeability and calm effect of releiving, and is permeable to play at neoplastic skin tip and relax Slow quelling effect, to play antipruritic effect.
Embodiment described above is only that the preferred embodiment of the present invention is described, not to the design of the present invention It is defined with range, under the premise of not departing from design concept of the present invention, ordinary engineering and technical personnel is to this hair in this field The all variations and modifications that bright technical solution is made should all fall into protection scope of the present invention, claimed skill of the invention Art content is all documented in technology claim.

Claims (6)

1. a kind of anti-bacterial, anti-itching dressing containing tea oil, it is characterised in that:It is made of tea oil and gel-type vehicle;Wherein tea oil Content be 0.1%-25%, the content of gel-type vehicle is 75%-99.9%.
2. a kind of anti-bacterial, anti-itching dressing containing tea oil according to claim 1, it is characterised in that:Meng in tea oil Content >=30% of alkene -1- alcohol;
A kind of anti-bacterial, anti-itching dressing containing tea oil according to claim 1, it is characterised in that:The gel-type vehicle by Following mass percent at being grouped as:Alcohol 1%-15%, thickener 0.1%-5%, emulsifier 0.1%-5%, surplus are water.
3. a kind of anti-bacterial, anti-itching dressing containing tea oil according to claim 3, it is characterised in that:The alcohol is by second Alcohol, ethylene glycol, propylene glycol, glycerine one or more of work as composition.
4. a kind of anti-bacterial, anti-itching dressing containing tea oil according to claim 3, it is characterised in that:The thickener by Sodium carboxymethylcellulose, carbomer, Sodium Polyacrylate, one or more compositions in sodium alginate.
5. a kind of anti-bacterial, anti-itching dressing containing tea oil according to claim 3, it is characterised in that:The emulsifier by Emulsifier 343, Pemulen polymer, Biobase S, one or more compositions in Delta emulsifiers.
6. a kind of preparation method of dressing described in claim 1, it is characterised in that:Gel is added in the tea tree oil component of oiliness It is uniformly mixed in matrix and forms tea tree oleogel.
CN201810391567.4A 2018-04-27 2018-04-27 A kind of anti-bacterial, anti-itching dressing and preparation method thereof containing tea oil Pending CN108404201A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810391567.4A CN108404201A (en) 2018-04-27 2018-04-27 A kind of anti-bacterial, anti-itching dressing and preparation method thereof containing tea oil

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810391567.4A CN108404201A (en) 2018-04-27 2018-04-27 A kind of anti-bacterial, anti-itching dressing and preparation method thereof containing tea oil

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CN108404201A true CN108404201A (en) 2018-08-17

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111166930A (en) * 2019-11-19 2020-05-19 北京理工大学 Sodium alginate hydrogel medical dressing and preparation method thereof
CN113274372A (en) * 2021-05-17 2021-08-20 长春工业大学 Preparation method of microneedle patch for quickly and efficiently relieving itching due to mosquito bites

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1411857A (en) * 2002-10-08 2003-04-23 重庆康尔威药业股份有限公司 Tea oil ointment and suppository
CN1524587A (en) * 2003-09-18 2004-09-01 云大科技股份有限公司 Nursing wet towel using tea plant oil as antibacterial and fungistatic agent and production method thereof
CN1994477A (en) * 2006-12-27 2007-07-11 褚省吾 Method for preparing medical dressing
CN103405746A (en) * 2013-07-29 2013-11-27 朱耀灯 Gel capable of fast removing acne
CN103520708A (en) * 2013-10-22 2014-01-22 易金阳 Composition capable of promoting wound healing and reducing scarring
CN105288707A (en) * 2015-10-23 2016-02-03 东莞市达庆医疗器械有限公司 Itching-relieving hydrogel dressing and preparation method thereof
CN105362351A (en) * 2015-12-16 2016-03-02 成都昊健生物科技有限责任公司 Medicine composition for treating cutaneous pruritus disease and application thereof

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1411857A (en) * 2002-10-08 2003-04-23 重庆康尔威药业股份有限公司 Tea oil ointment and suppository
CN1524587A (en) * 2003-09-18 2004-09-01 云大科技股份有限公司 Nursing wet towel using tea plant oil as antibacterial and fungistatic agent and production method thereof
CN1994477A (en) * 2006-12-27 2007-07-11 褚省吾 Method for preparing medical dressing
CN103405746A (en) * 2013-07-29 2013-11-27 朱耀灯 Gel capable of fast removing acne
CN103520708A (en) * 2013-10-22 2014-01-22 易金阳 Composition capable of promoting wound healing and reducing scarring
CN105288707A (en) * 2015-10-23 2016-02-03 东莞市达庆医疗器械有限公司 Itching-relieving hydrogel dressing and preparation method thereof
CN105362351A (en) * 2015-12-16 2016-03-02 成都昊健生物科技有限责任公司 Medicine composition for treating cutaneous pruritus disease and application thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111166930A (en) * 2019-11-19 2020-05-19 北京理工大学 Sodium alginate hydrogel medical dressing and preparation method thereof
CN113274372A (en) * 2021-05-17 2021-08-20 长春工业大学 Preparation method of microneedle patch for quickly and efficiently relieving itching due to mosquito bites

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Application publication date: 20180817

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