CN108403803A - A kind of compound Chinese medicinal preparation of prevention diabetic cardiovascular complications - Google Patents
A kind of compound Chinese medicinal preparation of prevention diabetic cardiovascular complications Download PDFInfo
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Abstract
A kind of compound Chinese medicinal preparation of prevention diabetic cardiovascular complications, belongs to technical field of traditional Chinese medicines.Its by following parts by weight Chinese medicinal composition：Raw 20~40 parts of Rhizoma Atractylodis Macrocephalae, 10~30 parts of raw hawthorn, 5~25 parts of Radix Salviae Miltiorrhizae, 5~25 parts of root of Chinese trichosanthes, 20~40 parts of pueraria lobata, 20~40 parts of raw oyster, 5~25 parts of ganoderma lucidum, 5~25 parts of Snakegourd Fruit, 5~25 parts of ground bettle, 10~30 parts of Semen Vaccariae (parched), 5~25 parts of vaccini,fructus.A kind of compound Chinese medicinal preparation of above-mentioned prevention diabetic cardiovascular complications, compatibility is reasonable, has effects that transport that spleenization is turbid, blood circulation promoting and dispersing pathogen accumulation, and safety has no toxic side effect, has good effect to prevention diabetic cardiovascular complications.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicines, and in particular to a kind of Chinese medicine compound prescription system of prevention diabetic cardiovascular complications
Agent.
Background technology
Diabetes（Diabetes mellitus, DM）It is one group of metabolism characterized by chronic blood glucose levels increase
Property disease, be by insulin secretion and（Or）It acts on caused by defect.Long-term carbohydrate and fat, protein metabolism are disorderly
Multisystem damage can disorderly be caused, wherein diabetic cardiovascular disease change is the common complication of diabetes, and leads to patient of diabetes
The main reason for person is dead.Studies have shown that with the non-diabetic patients for having myocardial infarction past medical history cardiac muscle occurs for diabetic
The risk of infarct is suitable.The presence of the risk factors such as hyperglycemia and insulin resistance, can reduce nitric oxide production activity, influence blood
The diastolic function of pipe, while blood vessel being stimulated to generate large amount of cell factor, promote inflammatory reaction and oxidative stress, improves Vascular permeability
Property, the integrality of blood vessel endothelium is destroyed, the formation of blood vessel endothelium dysfunction is caused.In atherosclerosis
（Atherosclerosis, AS）The initial stage of formation, blood vessel endothelium dysfunction still have invertibity, reverse blood vessel endothelium early
Dysfunction is to inhibiting AS progress, to prevent the occurrence and development of myocardial ischemia disease to have important clinical meaning.Glycosuria
Sick cardiovascular complication is a kind of disease of complexity, is related to the pathological change of more histoorgans, single control blood glucose and anti-blood
Platelet aggregation etc. not can effectively prevent the occurrence and development of insulin resistance relevant blood vessel endothelial dysfunction.Traditional Chinese medicine is by the disease
It is attributed to the scopes such as " diabete ", " obstruction of qi in the chest ", " palpitaition ", the present invention makees the intervention of diabetic cardiovascular complications occurrence and development
With being that multi-angle is multifaceted, there is unique advantage in terms for the treatment of diabetic cardiovascular disease becomes this kind of complex disease.
Invention content
In view of the problems of the existing technology, it is an object of the invention to design a kind of prevention diabetic cardiovascular of offer simultaneously
Send out the technical solution of the compound Chinese medicinal preparation of disease.
The compound Chinese medicinal preparation of a kind of prevention diabetic cardiovascular complications, it is characterised in that by following parts by weight
Chinese medicinal composition：Raw 20~40 parts of Rhizoma Atractylodis Macrocephalae, 10~30 parts of raw hawthorn, 5~25 parts of Radix Salviae Miltiorrhizae, 5~25 parts of root of Chinese trichosanthes, pueraria lobata 20~40
Part, 20~40 parts of raw oyster, 5~25 parts of ganoderma lucidum, 5~25 parts of Snakegourd Fruit, 5~25 parts of ground bettle, 10~30 parts of Semen Vaccariae (parched), south
5~25 parts of principal divisor.
The compound Chinese medicinal preparation of a kind of prevention diabetic cardiovascular complications, it is characterised in that by following parts by weight
Chinese medicinal composition：Raw 25~35 parts of Rhizoma Atractylodis Macrocephalae, 15~25 parts of raw hawthorn, 10~20 parts of Radix Salviae Miltiorrhizae, 10~20 parts of root of Chinese trichosanthes, pueraria lobata 25~
35 parts, 25~35 parts of raw oyster, 10~20 parts of ganoderma lucidum, 10~20 parts of Snakegourd Fruit, 10~20 parts of ground bettle, Semen Vaccariae (parched) 15~25
Part, 10~20 parts of vaccini,fructus.
The compound Chinese medicinal preparation of a kind of prevention diabetic cardiovascular complications, it is characterised in that by following parts by weight
Chinese medicinal composition：Raw 30 parts of Rhizoma Atractylodis Macrocephalae, 20 parts of raw hawthorn, 15 parts of Radix Salviae Miltiorrhizae, 15 parts of root of Chinese trichosanthes, 30 parts of pueraria lobata, 30 parts of raw oyster, ganoderma lucidum
15 parts, 15 parts of Snakegourd Fruit, 15 parts of ground bettle, 20 parts of Semen Vaccariae (parched), 15 parts of vaccini,fructus.
Raw Rhizoma Atractylodis Macrocephalae, sweet, bitter, temperature.Returns spleen, stomach.Have effects that spleen is transported in invigorating the spleen, spleen-QI transporting the essence to the whole body can be helped to fill four rushing works
With, make pure and impure score, it is wet turbid not give birth to.Modern pharmacological studies have shown that raw Baizhu, which has, adjusts gastrointestinal function and hypoglycemic
Effect.
Raw hawthorn, sour, sweet, tepor.Returns spleen, stomach, Liver Channel.It is warm-natured enter blood system, can pass through qi and blood, promoting blood circulation, and energy
Change turbid lipid-loweringing.Modern pharmacological studies have shown that lipolytic enzyme promotes lipolysis, extract energy coronary artery dilator to increase in hawthorn
Coronary blood flow, and can reducing blood lipid and antiatherosclerosis.
Radix Salviae Miltiorrhizae, it is bitter, it is slightly cold.Converge to heart and liver channels.Work(is apt to promoting blood circulation and removing blood stasis, removing blood stasis for promoting tissue regeneration, is treatment hematogenous blockage, stagnation of blood stasis
Key medicine, have a title of " small four object " and among promoting circulation of blood and the energy of help.Modern pharmacological studies have shown that there is Radix Salviae Miltiorrhizae expansion to be preced with
Arteries and veins increases coronary blood flow, adjusts blood fat, reduces the effect of blood viscosity, antiatherosclerosis and anti-inflammatory and antalgic.
Root of Chinese trichosanthes, sweet, slight bitter, is slightly cold.It attaches to the lung and stomach meridians.It clearing lung-heat sthenia gastropyrexia and can promote the production of body fluid to quench thirst, there is heat-clearing not
Just, the characteristics of enriching yin does not hinder spleen is the key medicine for treating diabetes to wound.Modern pharmacological studies have shown that root of Chinese trichosanthes agglutinin crude product has
Reduce the effect of blood glucose.
Pueraria lobata, it is sweet, pungent, it is cool.Returns spleen, stomach, lung channel.The gas of the clear sun of taste can be inspired to rise, and have the work(to promote the production of body fluid to quench thirst,
Acrid flavour can manage it, the energy with clearing and activating the channels and collaterals.Modern pharmacological studies have shown that Pueraria Flavonid can expand coronary artery blood vessel and the cerebrovascular, Pueraria lobota
Heterogeneity contained by root also has the effects that hypoglycemic, reducing blood lipid, anti-oxidant.
Raw oyster, it is salty, it is slightly cold.Return liver, courage, kidney channel.Have the function of checking exuberance of yang tonifying yin, increase strength and softening and resolving hard mass.It is modern
Pharmacological research shows that oyster active peptides have the function of promoting islet tissue reparation and restore its secretion, and oyster extract has drop
The effect of hypoglycemia.
Ganoderma lucidum, sweet and neutral.The thoughts of returning home, lung, liver and kidney channel.Energy bushing blood, invigorating heart gas, tranquilizing mind have to fill blood and do not help heat
Feature.Modern pharmacological studies have shown that ganoderma lucidum can reduce blood viscosity, increase myocardial contractive power, increase coronary blood flow, ganoderma lucidum is more
The adjustable glycolipid metabolism approach of sugar.
Snakegourd Fruit, it is sweet, it is slightly cold.Return lung, stomach, large intestine channel.Have the function of clearing heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, but can sharp gas open it is strongly fragrant.
Modern pharmacological studies have shown that Snakegourd Fruit has expansion coronary artery, increase coronary blood flow, anticoagulation and reduction serum cholesterol etc. are a variety of
Activity, it is horizontal that water extract can significantly increase hungry Rabbits ' Blood Sugar.
Ground bettle, it is salty, it trembles with fear.Return liver warp.Property is apt to walk to alter, and has the function of invigorate blood circulation dissipating bind.Modern pharmacological studies have shown that
Ground bettle aqueous extract plays the role of regulating lipid metabolism, resisting oxidation free radical, protection vascular endothelial cell.
The seed of cowherb, it is bitter, it puts down.Return liver, stomach.It is good at promoting blood circulation, invigorate blood circulation dissipating bind.Modern pharmacological studies have shown that king
Do not stay row can anti-angiogenesis, n-butanol extract can inhibit the proliferation of endothelial cell, migration, adherency, and Human Umbilical Vein Endothelial Cells have
The clotting time can be extended after good protective effect, the seed of cowherb and Radix Salviae Miltiorrhizae compatibility, reduce whole blood viscosity.
Vaccini,fructus, acid, sweet and neutral.Return liver and kidney channel.With filling liver kidney, strengthening the bones and muscles, the effect of solid essence.Chinese medicine thinks " long
Disease and kidney ", therefore shield kidney essense and QI invigorating are cared for this.
Production method：
A kind of compound Chinese medicinal preparation of prevention diabetic cardiovascular complications, the preparation is one of following dosage form：1. decoction；
2. granule；3. pill；4. capsule.The preparation by prevention diabetic cardiovascular complications herbal mixture water extract and
Pharmaceutically acceptable excipients form.
The preparation is prevention diabetic cardiovascular complications decoction, the prevention diabetic cardiovascular complications decoction
It is made as follows：After precise, be included in raw oyster and first boil 30min, after enter raw Rhizoma Atractylodis Macrocephalae, raw hawthorn, Radix Salviae Miltiorrhizae, root of Chinese trichosanthes,
Pueraria lobata, ganoderma lucidum, Snakegourd Fruit, ground bettle, Semen Vaccariae (parched), vaccini,fructus use slow boiling instead and maintain 20min or so, will decoct after boiling by intense fire
Liquid is poured out.Clear water is reentered, all drugs boil by intense fire, use slow boiling maintenance instead, pour out decocting liquid, decocting liquid will mix twice up to preventing
The traditional Chinese herbal decoction of diabetic cardiovascular complications.
The preparation is prevention diabetic cardiovascular complications granule, the prevention diabetic cardiovascular complications
Granula is made as follows：Precise gives birth to Rhizoma Atractylodis Macrocephalae, raw hawthorn, Radix Salviae Miltiorrhizae, root of Chinese trichosanthes, raw oyster, pueraria lobata, ganoderma lucidum, Snakegourd Fruit, soil
Soft-shelled turtle worm, Semen Vaccariae (parched), vaccini,fructus, chopping or crushing appropriate set suitable for decocting in container, suitable quantity of water are added to make submergence medicinal material,
After impregnating appropriate time, heating is boiled, and isolates decocting liquid after a certain period of time, and the dregs of a decoction repeat to decoct 2~3 times, collect each fried liquid,
After centrifuging or settling filtration, low temperature is concentrated into normal concentration, and the medicinal extract and auxiliary material that will be condensed into certain weight proportion are mediated, necessary
When be added suitable wetting agent, whole grain, the dry Chinese herbal granules to get prevention diabetic cardiovascular complications.
The preparation is prevention diabetic cardiovascular complications pill, the prevention diabetic cardiovascular complications pill
It is made as follows：Precise gives birth to Rhizoma Atractylodis Macrocephalae, raw hawthorn, Radix Salviae Miltiorrhizae, root of Chinese trichosanthes, raw oyster, pueraria lobata, ganoderma lucidum, Snakegourd Fruit, ground beetle
Worm, Semen Vaccariae (parched), vaccini,fructus are ground into fine powder, sieving, mixing, and refined honey closes medicine, rub ball with the hands, dry to get prevention diabetes
The medicine pill of cardiovascular complication.
The preparation is prevention diabetic cardiovascular complications capsule, the prevention diabetic cardiovascular complications glue
Wafer is made as follows：Precise gives birth to Rhizoma Atractylodis Macrocephalae, raw hawthorn, Radix Salviae Miltiorrhizae, root of Chinese trichosanthes, raw oyster, pueraria lobata, ganoderma lucidum, Snakegourd Fruit, soil
Soft-shelled turtle worm, Semen Vaccariae (parched), vaccini,fructus, chopping or crushing appropriate set suitable for decocting in container, suitable quantity of water are added to make submergence medicinal material,
After impregnating appropriate time, heating is boiled, and isolates decocting liquid after a certain period of time, and the dregs of a decoction repeat to decoct 2~3 times, collect each fried liquid,
After centrifuging or settling filtration, low temperature is concentrated into normal concentration, is added or is added without pharmaceutically acceptable excipients, obtain
Prevent the content of the capsule of diabetic cardiovascular complications.
A kind of compound Chinese medicinal preparation of above-mentioned prevention diabetic cardiovascular complications, compatibility is reasonable, turbid with fortune spleenization,
Blood circulation promoting and dispersing pathogen accumulation effect, and safety has no toxic side effect, has good effect to prevention diabetic cardiovascular complications.
Specific implementation mode
It further illustrates the present invention with reference to embodiments.
Embodiment 1
A kind of compound Chinese medicinal preparation of prevention diabetic cardiovascular complications, by the Chinese medicinal composition of following weight：Raw Rhizoma Atractylodis Macrocephalae 30
G, 20 g of raw hawthorn, 15 g of Radix Salviae Miltiorrhizae, 15 g of root of Chinese trichosanthes, 30 g of pueraria lobata, 30 g of raw oyster, 15 g of ganoderma lucidum, 15 g of Snakegourd Fruit, ground bettle
15 g, 20 g of Semen Vaccariae (parched), vaccini,fructus 15g.
Embodiment 2
A kind of compound Chinese medicinal preparation of prevention diabetic cardiovascular complications, by the Chinese medicinal composition of following weight：Raw Rhizoma Atractylodis Macrocephalae 25
G, 15 g of raw hawthorn, 10 g of Radix Salviae Miltiorrhizae, 10 g of root of Chinese trichosanthes, 25 g of pueraria lobata, 25 g of raw oyster, 10 g of ganoderma lucidum, 10 g of Snakegourd Fruit, ground bettle
10 g, 15 g of Semen Vaccariae (parched), vaccini,fructus 10g.
Embodiment 3
A kind of compound Chinese medicinal preparation of prevention diabetic cardiovascular complications, by the Chinese medicinal composition of following weight：Raw Rhizoma Atractylodis Macrocephalae 35
G, 25 g of raw hawthorn, 20 g of Radix Salviae Miltiorrhizae, 15 g of root of Chinese trichosanthes, 35 g of pueraria lobata, 35 g of raw oyster, 20 g of ganoderma lucidum, 15 g of Snakegourd Fruit, ground bettle
15 g, 15 g of Semen Vaccariae (parched), vaccini,fructus 5g.
Embodiment 4
A kind of compound Chinese medicinal preparation of prevention diabetic cardiovascular complications, by the Chinese medicinal composition of following weight：Raw Rhizoma Atractylodis Macrocephalae 20
G, 10 g of raw hawthorn, 5 g of Radix Salviae Miltiorrhizae, 5 g of root of Chinese trichosanthes, 20 g of pueraria lobata, 20 g of raw oyster, 5 g of ganoderma lucidum, 5 g of Snakegourd Fruit, 5 g of ground bettle,
10 g of Semen Vaccariae (parched), vaccini,fructus 10g.
Embodiment 5
A kind of compound Chinese medicinal preparation of prevention diabetic cardiovascular complications, by the Chinese medicinal composition of following weight：Raw Rhizoma Atractylodis Macrocephalae 40
G, 30 g of raw hawthorn, 25 g of Radix Salviae Miltiorrhizae, 15 g of root of Chinese trichosanthes, 40 g of pueraria lobata, 40 g of raw oyster, 25 g of ganoderma lucidum, Snakegourd Fruit 15g, ground bettle
15 g, Semen Vaccariae (parched) 25g, vaccini,fructus 15g.
Test example 1
1 clinical data
1.1 general information
240 patients are the patient to go to a doctor in clinic of Zhejiang University of Traditional Chinese Medicine in January, 2016 in December, 2017, according to meter
Calculation machine randomly selects number and is divided into control group and treatment group, every group each 120.Two groups of Genders, the baseline at age and the course of disease
Data compares, no significant difference（P＞ 0.05）, it is comparable.Refer to table 1.
1 two groups of patient baseline's data of table compare
1.2 diagnostic criteria
Diabetes B patient meets《Type 2 Diabetes In China guideline of prevention and treatment（Version in 2010）》Diagnostic criteria.
1.3 inclusion criteria
1. meeting above-mentioned diagnostic criteria；2. age 35-70 Sui；3. course of disease 1 year or more；4. voluntary participation simultaneously signs informed consent form
Person.
1.4 exclusion criteria
1. not meeting the patient of above-mentioned diagnostic criteria and inclusion criteria；2. the severe diabetes mellitus such as ketoacidosis, diabetes are simultaneously
Send out disease patient；3. merging systems serious disease and the mental patients such as angiocarpy, nerve, breathing, digestion, uropoiesis；4. I type glycosurias
Disease and other secondary diabetes；5. gestation and women breast-feeding their children.
2 therapies
Control group gives doctor trained in Western medicine routine glucose-lowering treatment, and treatment group controls on the basis of control group is treated to transport that spleenization is turbid, Huoxue San " connection,
It gives from quasi- activating spleen and blood circulation dissipating bind side：Raw Rhizoma Atractylodis Macrocephalae 30g, raw hawthorn 20g, Radix Salviae Miltiorrhizae 15g, root of Chinese trichosanthes 15g, pueraria lobata 30g, raw oyster 30g,
Ganoderma lucidum 15g, Snakegourd Fruit 15g, ground bettle 15g, seed of cowherb 20g, vaccini,fructus 15g.Daily 1 dose, decocting 400mL, point early, evening is twice
It warmly takes.The course for the treatment of is 4 weeks, and treatment carries out therapeutic evaluation after 4 weeks.Two groups of patients of tested period carry out Diabetes Mellitus Knowledge education and
Diabetic diet instructs.
3 therapeutic evaluatioies
3.1 observation item
1. insulin resistance index of correlation, including fasting blood-glucose（FBG）, fasting insulin（FINS）And insulin resistance index
（HOMA-IR）；2. vasculitic index interleukin-6（Interleukin-6, IL-6）, using ELISA kits
（GeneTech）Detection.
3.2 statistical tools and data processing
UsingSPSS16.0 statistical softwares, enumeration data useχ 2 It examines, measurement data usestIt examines, ranked data use order
And inspection.
4 treatment results
The pretherapy and post-treatment insulin resistance index of correlation of 4.1 two groups of patients compares
Compare as can be seen from Table 2, two groups of diabetic therapy proinsulins resist index of correlation, no significant difference（P＞
0.05）, it is comparable.FBG, FINS, HOMA-IR improvement are superior to control group after treatment group's treatment, and difference has statistics
Meaning（P<0.05）, insulin resistance index of correlation, which improves, after prompting treatment group to treat is substantially better than control group.
The pretherapy and post-treatment insulin resistance index of correlation of 2 two groups of patients of table compares（ ±s）
Note：Compared with after control group treatment,* P＜ 0.05.
The pretherapy and post-treatment IL-6 levels of 4.2 two groups of patients compare
As shown in Table 3, the horizontal of IL-6 is compared before two groups of diabetic therapies, no significant difference（P＞ 0.05）, tool
There is comparativity.IL-6 levels are less than control group after treatment group's treatment, and difference has statistical significance（P＜ 0.05）, prompt treatment
Horizontal improve of IL-6 is substantially better than control group after group treatment.
The horizontal variation of 3 two groups of pretherapy and post-treatment IL-6 of patient of table（ ±s, ng/L）
Note：Compared with after control group treatment,* P＜ 0.05.
5 discuss
Diabetic cardiovascular disease change is the common complication of diabetes, and the presence of the factors such as hyperglycemia and insulin resistance makes blood
The diastolic function of pipe is impaired, and with activated endothelial cell, so that the synthesis of endothelium-derived active material is secreted and be affected, to
Lead to lasting vessel retraction spasm, inflammatory reaction, platelet activation, smooth muscle cell proliferation and vascular remodeling, Atherosclerosis
Change progressive exacerbation or unstable plaque rupture and myocardial infarction occurs.Traditional Chinese medicine thinks that the disease is worked as and is attributed to " diabete ", " chest
The scopes such as numbness ", " palpitaition ", under physiological conditions, blood glucose, blood fat are needed by human by taste institute metaplasia from essence of water and grain
Nutriment.But if eating and drinking without temperance, throw off restraint and eat greasy and surfeit flavour, or the cool drink of happiness is cold, or is hungry full variable, with the passing of time impairing the spleen and stomach, taste
Transporting mistake department, then essence of water and grain be unable to metaplasia qi and blood, it is pure and impure effectively to distinguish, cause it is wet be polymerized to phlegm, in foul smell slime flux arteries and veins, this
When blood in high-caliber sugar, fat become the category of phlegm wet, foul smell.It is jammed sering as phlegm is turbid, influences the operation of qi and blood, lead to gas
Blood stasis is stagnant；And phlegm is turbid is reluctant to leave with the passing of time, then it can be at the card of phlegm and blood stasis.Diabetic cardiovascular disease change from the above analysis mainly relates to
And two aspects, when the dysfunction of the spleen in transport, second is that phlegm and blood stasis.Therefore should spleenization is turbid, blood circulation promoting and dispersing pathogen accumulation is therapeutic rules to transport, to reach
The purpose for the treatment of both manifestation and root cause of disease.The present embodiment passes through raw Rhizoma Atractylodis Macrocephalae, raw hawthorn, Radix Salviae Miltiorrhizae, root of Chinese trichosanthes, pueraria lobata, raw oyster, ganoderma lucidum, Snakegourd Fruit, soil
Soft-shelled turtle worm, the seed of cowherb and day principal divisor rational proportion, by the effect of complementing each other between each component, reach fortune spleenization it is turbid,
The purpose of blood circulation promoting and dispersing pathogen accumulation can effectively prevent diabetic cardiovascular complications.
It is the model case of the present invention below：
Case 1：
Lee, female, 57 years old.With diabetes medical history 3 years, metformin hydrochloride tablet, a 0.5g are taken（2）, mouth 3 times a day
Clothes.Recently patient feels palpitaition, and fasting blood-glucose 10.8mmol/L, very, urine is more for dry, stomach receive can, stool is viscous, a line on the 1st~2,
Tongue is red, and tongue is thin white, intermittent pulse.Electrocardio illustrates frequent premature ventricular beatss.Diagnosis：Doctor trained in Western medicine diagnoses：Diabetes B frequent premature ventricular beatss
Tcm diagnosis：Diabete palpitaition.The traditional Chinese herbal decoction treatment is given, further consultation palpitaition, dry, the symptoms such as viscous of defecating are apparent after 2 weeks
Mitigate, fasting blood-glucose 7.5mmol/L, metformin hydrochloride tablet be kept to one time 2, take orally 2 times a day；Further consultation palpitaition, mouth after 4 weeks
The symptoms such as dry disappear, and stool and urine is normal, fasting blood-glucose 7.1mmol/L, and check electrocardio illustrates the substantially normal electrocardio of sinus rhythm
Figure.
Case 2：
Certain, male together, 49 years old.With diabetes medical history more than 1 year, antidiabetic drug is taken（Metformin hydrochloride tablet, repaglinide etc.）, effect
Fruit unobvious, fasting blood-glucose 9.2mmol/L, 140~160/90~100mmHg of blood pressure.There is precordialgia over the nearly moon, with chest
Bored, thirsty, difficulty in defecation, a line on the 2nd~4, tongue is red, there is purple plague purpura, and tongue is white, veins string.Electrocardio illustrates II, III, aVF, ST sections of V2~4
It forces down.Diagnosis：Doctor trained in Western medicine diagnoses：Diabetes B coronary heart disease tcm diagnosis：Diabete chest impediment and cardialgia.Give the traditional Chinese herbal decoction
Treatment, further consultation patient pectoralgia, symptom uncomfortable in chest are substantially reduced after 2 weeks, a line on the 1st of defecating, fasting blood-glucose 8.7mmol/L, blood pressure 130
~140/85~95mmHg.Further consultation feeling of oppression and pain in the chest symptom disappears after 4 weeks, and stool and urine is normal, fasting blood-glucose 7.0mmol/L, blood pressure
130~140/80~90mmHg, electrocardio illustrate sinus rhythm, normal ECG.Turn number formulary time in locality afterwards, glycemic control is flat
Surely, do not occur feeling of oppression and pain in the chest symptom again.
Claims (3)
1. a kind of compound Chinese medicinal preparation of prevention diabetic cardiovascular complications, it is characterised in that by the Chinese medicine group of following parts by weight
At：Raw 20~40 parts of Rhizoma Atractylodis Macrocephalae, 10~30 parts of raw hawthorn, 5~25 parts of Radix Salviae Miltiorrhizae, 5~25 parts of root of Chinese trichosanthes, 20~40 parts of pueraria lobata, life are male
20~40 parts of oyster, 5~25 parts of ganoderma lucidum, 5~25 parts of Snakegourd Fruit, 5~25 parts of ground bettle, 10~30 parts of Semen Vaccariae (parched), vaccini,fructus 5~
25 parts.
2. a kind of compound Chinese medicinal preparation of prevention diabetic cardiovascular complications as described in claim 1, it is characterised in that by
The Chinese medicinal composition of following parts by weight：Raw 25~35 parts of Rhizoma Atractylodis Macrocephalae, 15~25 parts of raw hawthorn, 10~20 parts of Radix Salviae Miltiorrhizae, root of Chinese trichosanthes 10~20
Part, 10~20 parts of ganoderma lucidum, 10~20 parts of Snakegourd Fruit, 10~20 parts of ground bettle, fries king at 25~35 parts of pueraria lobata, 25~35 parts of raw oyster
15~25 parts of row, 10~20 parts of vaccini,fructus are not stayed.
3. a kind of compound Chinese medicinal preparation of prevention diabetic cardiovascular complications as described in claim 1, it is characterised in that by
The Chinese medicinal composition of following parts by weight：Raw 30 parts of Rhizoma Atractylodis Macrocephalae, 20 parts of raw hawthorn, 15 parts of Radix Salviae Miltiorrhizae, 15 parts of root of Chinese trichosanthes, 30 parts of pueraria lobata, life are male
30 parts of oyster, 15 parts of ganoderma lucidum, 15 parts of Snakegourd Fruit, 15 parts of ground bettle, 20 parts of Semen Vaccariae (parched), 15 parts of vaccini,fructus.
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Non-Patent Citations (3)
| Title |
|---|
| LILI WANG: "Salvia Miltiorrhiza: A Potential Red Light to the Development of Cardiovascular Diseases", 《CURRENT PHARMACEUTICAL DESIGN》 * |
| 魏执真: "《名老中医魏执真心血管病经验发挥》", 30 June 2017, 北京：中国协和医科大学出版社 * |
| 黄煜: "从脾论治糖尿病之我见 ", 《中外医疗》 * |
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