CN108379541A - Chinese medicine composition and preparation method thereof for drug rehabilitation - Google Patents
Chinese medicine composition and preparation method thereof for drug rehabilitation Download PDFInfo
- Publication number
- CN108379541A CN108379541A CN201810481147.5A CN201810481147A CN108379541A CN 108379541 A CN108379541 A CN 108379541A CN 201810481147 A CN201810481147 A CN 201810481147A CN 108379541 A CN108379541 A CN 108379541A
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Classifications
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- A61K36/8988—Gastrodia
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Abstract
The Chinese medicine composition and preparation method thereof that the present invention relates to a kind of for drug rehabilitation.Raw material components include ginger, Luzon fruit, Radix Codonopsis, Radix Astragali, Chinese prickly ash, Radix Glycyrrhizae, Lappula echinata, prepared rehmannia root, American Ginseng, styrax, cushaw seedling, grass-leaved sweetflag, RADIX CHUNAMINSHEN, day name essence, mulberry fruit, frutus cnidii, Radix Isatidis, Radix Notoginseng, stiff silkworm, sealwort, cicada slough, storax, prepared fleece flower root, centipede, smilax, root of Chinese trichosanthes, ganoderma lucidum, Rhizoma Gastrodiae, scorpio, windproof and corydalis tuber.Traditional Chinese medicine composition formula provided by the invention is simple, raw material is sufficient, preparation method is easy, with excellent Fuzheng Jiedu, invigorate blood circulation sensible, adjusting organism physiology balance, recovery nervous function and other effects, it can be effective for the treatment and rehabilitation of drugs dependence withdrawal symptom, alleviate and eliminate the diseases such as the depression and anxiety mood of patient, vigilance disorders, and safe without toxic side effect；In addition, the Chinese medicine composition of the present invention is easy to use, the financial burden of patient can be substantially reduced, there is good commercial promise.
Description
Technical field
The present invention relates to field of Chinese herbal medicine technology, and in particular to a kind of Chinese medicine composition and its preparation side for drug rehabilitation
Method.
Background technology
The big malignant tumor taken drugs as present society, brings huge threat, to family and drug addict to social stability
Personal body and mind also results in prodigious harm.Specifically, drug abuse refers to taking various modes, using some with dependence potential
Substance, this use is unrelated with treatment purpose, as a result, misuser generates dependent status to the substance, forces them without stopping
Condition, which is pursued, to be used, once sucking habituation, will be unable to extricate oneself.Once there is drug addict in family, family is just incoherent.
Anti-additive medicament type is various in the world at present, and method is different, and Western medicine is occupied an leading position, but not in the prevalence of curative effect
Ideal, drug price are expensive, are also easy to produce the shortcomings of side effect.And Chinese medicine is used to quit drug abuse, since Chinese medicine type is various, compatibility is a variety of
It is various, until being still formulated so far without a kind of more effective treatment.It is more aobvious there is an urgent need for exploring a kind of novel effect based on this
It writes and the more perfect Chinese medicinal composition for detoxification of effect is most important.
Invention content
For the defects in the prior art, the present invention is intended to provide a kind of Chinese medicine composition and its preparation side for drug rehabilitation
Method.Traditional Chinese medicine composition formula provided by the invention is simple, raw material is sufficient, preparation method is easy, has excellent Fuzheng Jiedu, promoting blood circulation logical
Key, adjusting organism physiology balance, recovery nervous function and other effects, can be effective for the treatment of drugs dependence withdrawal symptom
And rehabilitation, alleviate and eliminate the diseases such as the depression and anxiety mood of patient, vigilance disorders, and safe without toxic side effect；In addition, this hair
The Chinese medicine composition of bright offer is easy to use, and cost is relatively low, can substantially reduce the financial burden of patient, before having good business
Scape.
For this purpose, the present invention provides the following technical solutions：
In a first aspect, the present invention provides a kind of Chinese medicine composition, raw material components by weight, including：Ginger 30~
40 parts by weight, 20~30 parts by weight of Luzon fruit, 30~40 parts by weight of Radix Codonopsis, 20~30 parts by weight of Radix Astragali, 20~25 weight of Chinese prickly ash
Part, 20~30 parts by weight of Radix Glycyrrhizae, 15~30 parts by weight of Lappula echinata, 15~20 parts by weight of prepared rehmannia root, 20~40 parts by weight of American Ginseng, peace
Fragrant 30~40 parts by weight of breath, 15~30 parts by weight of grass-leaved sweetflag, 15~20 parts by weight of RADIX CHUNAMINSHEN, 20~30 parts by weight of mulberry fruit, cnidium monnieri
Sub 20~30 parts by weight, 15~20 parts by weight of Radix Notoginseng, 30~40 parts by weight of stiff silkworm, 20~30 parts by weight of sealwort, prepared fleece flower root 10
~15 parts by weight, 20~30 parts by weight of centipede, 20~30 parts by weight of smilax, 10~15 parts by weight of root of Chinese trichosanthes, ganoderma lucidum 30~40
Parts by weight, 20~30 parts by weight of Rhizoma Gastrodiae, 25~30 weight of 20~30 parts by weight of scorpio, windproof 20~40 parts by weight and corydalis tuber
Part.
Preferably, the raw material of Chinese medicine composition further includes：20~30 parts by weight of cushaw seedling, 20~40 parts by weight of day name essence,
15~20 parts by weight of 15~25 parts by weight of storax, 20~30 parts by weight of cicada slough and Radix Isatidis.
Preferably, Chinese medicine composition is made of following raw material components：35 parts by weight of ginger, 25 parts by weight of Luzon fruit, Radix Codonopsis
35 parts by weight, 25 parts by weight of Radix Astragali, 22 parts by weight of Chinese prickly ash, 26 parts by weight of Radix Glycyrrhizae, 20 parts by weight of Lappula echinata, 15 parts by weight of prepared rehmannia root,
30 parts by weight of American Ginseng, 35 parts by weight of styrax, 25 parts by weight of cushaw seedling, 20 parts by weight of grass-leaved sweetflag, 16 parts by weight of RADIX CHUNAMINSHEN, day
Smart 30 parts by weight of name, 25 parts by weight of mulberry fruit, 25 parts by weight of frutus cnidii, 18 parts by weight of Radix Isatidis, 16 parts by weight of Radix Notoginseng, 35 weight of stiff silkworm
Measure part, 25 parts by weight of sealwort, 25 parts by weight of cicada slough, 20 parts by weight of storax, 13 parts by weight of prepared fleece flower root, 25 parts by weight of centipede,
25 parts by weight of smilax, 12 parts by weight of root of Chinese trichosanthes, 35 parts by weight of ganoderma lucidum, 25 parts by weight of Rhizoma Gastrodiae, 25 parts by weight of scorpio, windproof 30 weight
Measure part and 28 parts by weight of corydalis tuber.
Preferably, Chinese medicine composition is made of following raw material components：40 parts by weight of ginger, 20 parts by weight of Luzon fruit, Radix Codonopsis
40 parts by weight, 20 parts by weight of Radix Astragali, 25 parts by weight of Chinese prickly ash, 20 parts by weight of Radix Glycyrrhizae, 30 parts by weight of Lappula echinata, 15 parts by weight of prepared rehmannia root,
20 parts by weight of American Ginseng, 40 parts by weight of styrax, 20 parts by weight of cushaw seedling, 30 parts by weight of grass-leaved sweetflag, 15 parts by weight of RADIX CHUNAMINSHEN, day
Smart 40 parts by weight of name, 20 parts by weight of mulberry fruit, 30 parts by weight of frutus cnidii, 15 parts by weight of Radix Isatidis, 20 parts by weight of Radix Notoginseng, 30 weight of stiff silkworm
Measure part, 30 parts by weight of sealwort, 20 parts by weight of cicada slough, 25 parts by weight of storax, 10 parts by weight of prepared fleece flower root, 30 parts by weight of centipede,
20 parts by weight of smilax, 15 parts by weight of root of Chinese trichosanthes, 30 parts by weight of ganoderma lucidum, 30 parts by weight of Rhizoma Gastrodiae, 20 parts by weight of scorpio, windproof 40 weight
Measure part and 25 parts by weight of corydalis tuber.
Each bulk pharmaceutical chemicals for preparing Chinese medicine composition of the present invention are to be used as to match according to mass parts, can be according to corresponding in production
Ratio increase or reduce, as large-scale production can by kilogram or as unit of ton, small-scale production can also gram be unit, weight
Amount can increase or reduce, but the bulk pharmaceutical chemicals quality proportioning constant rate between each composition.
Second aspect, the present invention provide a kind of preparation method of Chinese medicine composition, include the following steps：S101：By each original
Material component clean, dry after crush；Raw material components after crushing are extracted using solvent, collect extracting solution；S102：It will carry
The thick paste that relative density is 1.15~1.35 when liquid being taken to be condensed into 70 DEG C, obtains Chinese medicine composition.
Preferably, the weight ratio of raw material components and solvent is 1：(5~30), solvent are deionized water, ethyl alcohol or ethanol water
Solution, and each raw material component is crushed to 60~200 mesh.
Preferably, the mass percentage concentration of ethanol water is 15%~20%.
Preferably, the condition of extraction is：Refluxing extraction 5h~10h under conditions of temperature is 45 DEG C~65 DEG C, extraction
Number is at least 1 time and preferably 3 times.
Chinese medicine composition prepared by the above method can be further prepared into pharmaceutically acceptable dosage form as needed.
The third aspect, Chinese medicine composition provided by the invention is in preparing the drug and/or medicated premix for drug rehabilitation
Application.
Using above-mentioned Chinese medicine composition protection scope of the present invention is also belonged to as drug made of active constituent.By will be above-mentioned
Pharmaceutical composition is prepared after directly preparing or being added pharmaceutically acceptable auxiliary material, can be made into any pharmaceutically acceptable
Dosage form.Include by taking external preparation as an example：Solution, patch, vina, tincture, gelling agent, liniment, aerosol, spray, ointment
Agent, suppository and plastics.The drug of above-mentioned various dosage forms can be prepared according to the conventional method of pharmaceutical field.
The above technical solution of the present invention has the following advantages over the prior art：
(1) applicant has found by numerous studies：Traditional Chinese medicine composition formula provided by the invention is simple, raw material is sufficient, system
Method is easy, there is sensible excellent Fuzheng Jiedu, promoting blood circulation, adjusting organism physiology balance, restore nervous function and other effects, energy
The depression and anxiety mood of patient, vigilance disorders are alleviated and are eliminated in enough treatments and rehabilitation effective for drugs dependence withdrawal symptom
Equal diseases, and safe without toxic side effect；In addition, Chinese medicine composition provided by the invention is easy to use, cost is relatively low, can substantially reduce
The financial burden of patient has good commercial promise.
(2) preparation method provided by the invention is used, the same of each bulk pharmaceutical chemicals active constituent can retained to greatest extent
When, the active ingredient in each raw medicinal material can be fully released, to make the Chinese medicine composition being finally prepared not
Only there is good drug effect, and be easy to absorb, and then be rapidly achieved the purpose for improving vertigo.
The additional aspect and advantage of the present invention will be set forth in part in the description, and will partly become from the following description
Obviously, or practice through the invention is recognized.
Specific implementation mode
The embodiment of technical solution of the present invention will be described in detail below.Following embodiment is only used for clearer
Illustrate technical scheme of the present invention, therefore be only used as example, and not intended to limit the protection scope of the present invention.
Experimental method in following embodiments is unless otherwise specified conventional method.
Test material as used in the following examples is unless otherwise specified to be commercially available from conventional reagent shop.
Quantitative test in following embodiment, is respectively provided with three repeated experiments, and data are the average value of three repeated experiments
Or mean+SD.
Ginger as used in the following examples, Luzon fruit, Radix Codonopsis, Radix Astragali, Chinese prickly ash, Radix Glycyrrhizae, Lappula echinata, prepared rehmannia root, American Ginseng,
Styrax, cushaw seedling, grass-leaved sweetflag, RADIX CHUNAMINSHEN, day name essence, mulberry fruit, frutus cnidii, Radix Isatidis, Radix Notoginseng, stiff silkworm, sealwort, cicada slough, Soviet Union
Blending, prepared fleece flower root, centipede, smilax, root of Chinese trichosanthes, ganoderma lucidum, Rhizoma Gastrodiae, scorpio, windproof and corydalis tuber meet Chinese Pharmacopoeia
Pertinent regulations under (version in 2017) each medicinal material item of text.Before feeding intake, by identification, ingredients material object and title phase
Symbol, quality comply with standard.
The present invention provides a kind of Chinese medicine composition, raw material components by weight, including：30~40 parts by weight of ginger, Lv
20~30 parts by weight of Song fruit, 30~40 parts by weight of Radix Codonopsis, 20~30 parts by weight of Radix Astragali, 20~25 parts by weight of Chinese prickly ash, Radix Glycyrrhizae 20~
30 parts by weight, 15~30 parts by weight of Lappula echinata, 15~20 parts by weight of prepared rehmannia root, 20~40 parts by weight of American Ginseng, styrax 30~40
Parts by weight, 15~30 parts by weight of grass-leaved sweetflag, 15~20 parts by weight of RADIX CHUNAMINSHEN, 20~30 parts by weight of mulberry fruit, 20~30 weight of frutus cnidii
Measure part, 15~20 parts by weight of Radix Notoginseng, 30~40 parts by weight of stiff silkworm, 20~30 parts by weight of sealwort, 10~15 parts by weight of prepared fleece flower root,
20~30 parts by weight of centipede, 20~30 parts by weight of smilax, 10~15 parts by weight of root of Chinese trichosanthes, 30~40 parts by weight of ganoderma lucidum, Rhizoma Gastrodiae
20~30 parts by weight, 25~30 parts by weight of 20~30 parts by weight of scorpio, windproof 20~40 parts by weight and corydalis tuber；And raw material components
It is preferred that further including：20~30 parts by weight of cushaw seedling, 20~40 parts by weight of day name essence, 15~25 parts by weight of storax, cicada slough 20~
15~20 parts by weight of 30 parts by weight and Radix Isatidis.
In addition, for the Chinese medicine composition of the present invention, the present invention specially devises preparation method, includes the following steps：
S101：Each raw material component is cleaned, dry after be crushed to 60~200 mesh；By the raw material components after crushing using molten
Agent extracts, and collects extracting solution.Wherein, the weight ratio of raw material components and solvent is 1：(5~30), solvent be deionized water,
Ethyl alcohol or ethanol water, and the mass percentage concentration of ethanol water is 15%~20%；The condition of extraction is：It is in temperature
The number of refluxing extraction 5h~10h under conditions of 45 DEG C~65 DEG C, extraction are at least 1 time and preferably 3 times.
S102：The thick paste that relative density is 1.15~1.35 when extracting solution is condensed into 70 DEG C, obtains Chinese medicine composition.
It illustrates With reference to embodiment：
Embodiment one
The present invention provides a kind of Chinese medicine composition, raw material components by weight, including：35 parts by weight of ginger, Luzon fruit
It is 25 parts by weight, 35 parts by weight of Radix Codonopsis, 25 parts by weight of Radix Astragali, 22 parts by weight of Chinese prickly ash, 26 parts by weight of Radix Glycyrrhizae, 20 parts by weight of Lappula echinata, ripe
15 parts by weight of glutinous rehmannia, 30 parts by weight of American Ginseng, 35 parts by weight of styrax, 25 parts by weight of cushaw seedling, 20 parts by weight of grass-leaved sweetflag, bright sand
Join smart 30 parts by weight of 16 parts by weight, day name, 25 parts by weight of mulberry fruit, 25 parts by weight of frutus cnidii, 18 parts by weight of Radix Isatidis, 16 weight of Radix Notoginseng
Measure part, 35 parts by weight of stiff silkworm, 25 parts by weight of sealwort, 25 parts by weight of cicada slough, 20 parts by weight of storax, 13 parts by weight of prepared fleece flower root,
25 parts by weight of centipede, 25 parts by weight of smilax, 12 parts by weight of root of Chinese trichosanthes, 35 parts by weight of ganoderma lucidum, 25 parts by weight of Rhizoma Gastrodiae, 25 weight of scorpio
Measure part, 28 parts by weight of windproof 30 parts by weight and corydalis tuber.
By above-mentioned raw materials component, preparation method using the present invention prepares Chinese medicine composition：
S101：Each raw material component is cleaned, dry after be crushed to 60 mesh；The raw material components for being crushed to 60 mesh are used into quality
The ethanol water of percentage concentration 20% refluxing extraction 8h at 50 DEG C collects extracting solution.Wherein, raw material components and quality percentage
The weight ratio of the ethanol water of concentration 20% is 1：5；Extraction time is 3 times.
S102：The thick paste that relative density is 1.20 when extracting solution is condensed into 70 DEG C, obtains Chinese medicine composition.
Embodiment two
The present invention provides a kind of Chinese medicine composition, raw material components by weight, including：40 parts by weight of ginger, Luzon fruit
It is 20 parts by weight, 40 parts by weight of Radix Codonopsis, 20 parts by weight of Radix Astragali, 25 parts by weight of Chinese prickly ash, 20 parts by weight of Radix Glycyrrhizae, 30 parts by weight of Lappula echinata, ripe
15 parts by weight of glutinous rehmannia, 20 parts by weight of American Ginseng, 40 parts by weight of styrax, 20 parts by weight of cushaw seedling, 30 parts by weight of grass-leaved sweetflag, bright sand
Join smart 40 parts by weight of 15 parts by weight, day name, 20 parts by weight of mulberry fruit, 30 parts by weight of frutus cnidii, 15 parts by weight of Radix Isatidis, 20 weight of Radix Notoginseng
Measure part, 30 parts by weight of stiff silkworm, 30 parts by weight of sealwort, 20 parts by weight of cicada slough, 25 parts by weight of storax, 10 parts by weight of prepared fleece flower root,
30 parts by weight of centipede, 20 parts by weight of smilax, 15 parts by weight of root of Chinese trichosanthes, 30 parts by weight of ganoderma lucidum, 30 parts by weight of Rhizoma Gastrodiae, 20 weight of scorpio
Measure part, 25 parts by weight of windproof 40 parts by weight and corydalis tuber.
By above-mentioned raw materials component, preparation method using the present invention prepares Chinese medicine composition：
S101：Each raw material component is cleaned, dry after be crushed to 200 mesh；The raw material components for being crushed to 200 mesh are used and are gone
Ionized water refluxing extraction 10h at 65 DEG C collects extracting solution.Wherein, the weight ratio of raw material components and deionized water is 1：30；It carries
It is 3 times to take number.
S102：The thick paste that relative density is 1.30 when extracting solution is condensed into 70 DEG C, obtains Chinese medicine composition.
Embodiment three
The present invention provides a kind of Chinese medicine composition, raw material components by weight, including：35 parts by weight of ginger, Luzon fruit
It is 25 parts by weight, 35 parts by weight of Radix Codonopsis, 25 parts by weight of Radix Astragali, 22 parts by weight of Chinese prickly ash, 26 parts by weight of Radix Glycyrrhizae, 20 parts by weight of Lappula echinata, ripe
15 parts by weight of glutinous rehmannia, 30 parts by weight of American Ginseng, 35 parts by weight of styrax, 25 parts by weight of cushaw seedling, 20 parts by weight of grass-leaved sweetflag, bright sand
Join smart 30 parts by weight of 16 parts by weight, day name, 25 parts by weight of mulberry fruit, 25 parts by weight of frutus cnidii, 18 parts by weight of Radix Isatidis, 16 weight of Radix Notoginseng
Measure part, 35 parts by weight of stiff silkworm, 25 parts by weight of sealwort, 25 parts by weight of cicada slough, 20 parts by weight of storax, 13 parts by weight of prepared fleece flower root,
25 parts by weight of centipede, 25 parts by weight of smilax, 12 parts by weight of root of Chinese trichosanthes, 35 parts by weight of ganoderma lucidum, 25 parts by weight of Rhizoma Gastrodiae, 25 weight of scorpio
Measure part, 28 parts by weight of windproof 30 parts by weight and corydalis tuber.
By above-mentioned raw materials component, preparation method using the present invention prepares Chinese medicine composition：
S101：Each raw material component is cleaned, dry after be crushed to 60 mesh；The raw material components for being crushed to 60 mesh are used into quality
The ethanol water of percentage concentration 20% refluxing extraction 8h at 50 DEG C collects extracting solution.Wherein, raw material components and quality percentage
The weight ratio of the ethanol water of concentration 20% is 1：5；Extraction time is 3 times.
S102：The thick paste that relative density is 1.20 when extracting solution is condensed into 70 DEG C, obtains Chinese medicine composition.
Example IV
The present invention provides a kind of Chinese medicine composition, raw material components by weight, including：40 parts by weight of ginger, Luzon fruit
It is 20 parts by weight, 40 parts by weight of Radix Codonopsis, 20 parts by weight of Radix Astragali, 25 parts by weight of Chinese prickly ash, 20 parts by weight of Radix Glycyrrhizae, 30 parts by weight of Lappula echinata, ripe
15 parts by weight of glutinous rehmannia, 20 parts by weight of American Ginseng, 40 parts by weight of styrax, 20 parts by weight of cushaw seedling, 30 parts by weight of grass-leaved sweetflag, bright sand
Join smart 40 parts by weight of 15 parts by weight, day name, 20 parts by weight of mulberry fruit, 30 parts by weight of frutus cnidii, 15 parts by weight of Radix Isatidis, 20 weight of Radix Notoginseng
Measure part, 30 parts by weight of stiff silkworm, 30 parts by weight of sealwort, 20 parts by weight of cicada slough, 25 parts by weight of storax, 10 parts by weight of prepared fleece flower root,
30 parts by weight of centipede, 20 parts by weight of smilax, 15 parts by weight of root of Chinese trichosanthes, 30 parts by weight of ganoderma lucidum, 30 parts by weight of Rhizoma Gastrodiae, 20 weight of scorpio
Measure part, 25 parts by weight of windproof 40 parts by weight and corydalis tuber.
By above-mentioned raw materials component, preparation method using the present invention prepares Chinese medicine composition：
S101：Each raw material component is cleaned, dry after be crushed to 200 mesh；The raw material components for being crushed to 200 mesh are used and are gone
Ionized water refluxing extraction 10h at 65 DEG C collects extracting solution.Wherein, the weight ratio of raw material components and deionized water is 1：30；It carries
It is 3 times to take number.
S102：The thick paste that relative density is 1.30 when extracting solution is condensed into 70 DEG C, obtains Chinese medicine composition.
In addition, the effect of in order to preferably evaluate each embodiment, carry out following experiment：
One, toxicity test
It is the small white mouse 80 (each 40 of male and female) of 18~22g to select weight, is divided into 4 groups, takes implementation of the present invention respectively
The Chinese medicine composition that example one to example IV is prepared.Specifically, the Chinese medicine composition 8g for taking the present invention, adds deionized water system
At concentrate 20mL, every small white mouse gives concentrate 1.2mL gavages, twice daily；Observation 30 days, small white mouse health are raw
It deposits, it is without any side effects；Blood picture, liver function, each organs and tissues state, the indifference compared with normal small white mouse is dissected and observed.
It is demonstrated experimentally that Chinese medicine composition provided by the invention is nontoxic.
Two, each embodiment Chinese medicine composition studies mouse morphine addiction Withdrawal Effect
It is the male ICR mouse 120 of 20~25g to select weight, is randomly divided into 6 groups, every group 20.Wherein, it is for first group
Model control group, second group is methadone positive group, third group to the 6th group be administration group, gavage embodiment one to implementation respectively
The Chinese medicine composition of example four.Specifically, morphine 100mg/Kg totally 14 times (7 days) is subcutaneously injected per 12h for each mouse, to cause morphine
Habituation model, each group is by drug shown in table 1 and dosage in urging first three day morning 9 of addiction:00 administration, once a day, each 0.2mL/
20g is administered once again before urging addiction；Allylnoroxymorphone 5mg/Kg is subcutaneously injected after per injection 6h and urges addiction, mouse is put into one immediately
In the drum of high 40cm diameters 30cm, the jump of the jump number of animals and each mouse after Allylnoroxymorphone is injected in 30min is observed and recorded
Number, the results are shown in Table 1.
1 Chinese medicine composition of the present invention of table inhibit mouse morphine addiction give up after jump_diffusion process
Model case：
Mr. Wang, male, 45 years old.Start within 05 year to suck " Calusena lansium ", it is rear to use heroin instead again, daily half gram or more.Once it used excessive
Kind method was given up, but with failure each end.Chinese medicine composition of the present invention voluntarily was taken to reach to required by quitting drug abuse in 10 years
The purpose thoroughly given up, before taking, patient's dim complexion is become thin, and a line on the five or six of defecating, amount is few, dry, apocleisis, tongue nature
It is red, yellow tongue fur, deep thready pulse.Taking Chinese medicine composition of the present invention, attack degree lightens two days later, and stool is dilute, has rosy cheeks after five days,
Tongue nature is light red, and tongue is thin white.Follow-up observation 1 year, patient mental is in good condition, does not relapse.
Certainly, the case where being enumerated in addition to embodiment one to example IV, the type and weight percent of other raw material components,
Condition and parameter in preparation process etc. are also possible.
Traditional Chinese medicine composition formula provided by the invention is simple, raw material is sufficient, preparation method is easy, have excellent Fuzheng Jiedu,
Invigorate blood circulation it is sensible, adjust organism physiology balance, restore nervous function and other effects, can be effective for drugs dependence withdrawal symptom
Treatment and rehabilitation, alleviate and eliminate the diseases such as the depression and anxiety mood of patient, vigilance disorders, and safe without toxic side effect；This
Outside, Chinese medicine composition provided by the invention is easy to use, and cost is relatively low, can substantially reduce the financial burden of patient, has fine
Commercial promise.
In the description of this specification, reference term " one embodiment ", " some embodiments ", " example ", " specifically show
The description of example " or " some examples " etc. means specific features, structure, material or spy described in conjunction with this embodiment or example
Point is included at least one embodiment or example of the invention.In the present specification, schematic expression of the above terms are not
It must be directed to identical embodiment or example.Moreover, particular features, structures, materials, or characteristics described can be in office
It can be combined in any suitable manner in one or more embodiments or example.In addition, without conflicting with each other, the skill of this field
Art personnel can tie the feature of different embodiments or examples described in this specification and different embodiments or examples
It closes and combines.
Although the embodiments of the present invention has been shown and described above, it is to be understood that above-described embodiment is example
Property, it is not considered as limiting the invention, those skilled in the art within the scope of the invention can be to above-mentioned
Embodiment is changed, changes, replacing and modification.
Claims (9)
1. a kind of Chinese medicine composition, which is characterized in that raw material components by weight, including：
30~40 parts by weight of ginger, 20~30 parts by weight of Luzon fruit, 30~40 parts by weight of Radix Codonopsis, 20~30 parts by weight of Radix Astragali, flower
20~25 parts by weight of green pepper, 20~30 parts by weight of Radix Glycyrrhizae, 15~30 parts by weight of Lappula echinata, 15~20 parts by weight of prepared rehmannia root, American Ginseng 20
~40 parts by weight, 30~40 parts by weight of styrax, 15~30 parts by weight of grass-leaved sweetflag, 15~20 parts by weight of RADIX CHUNAMINSHEN, mulberry fruit 20~
30 parts by weight, 20~30 parts by weight of frutus cnidii, 15~20 parts by weight of Radix Notoginseng, 30~40 parts by weight of stiff silkworm, 20~30 weight of sealwort
Part, 10~15 parts by weight of prepared fleece flower root, 20~30 parts by weight of centipede, 20~30 parts by weight of smilax, 10~15 weight of root of Chinese trichosanthes
Part, 30~40 parts by weight of ganoderma lucidum, 20~30 parts by weight of Rhizoma Gastrodiae, 20~30 parts by weight of scorpio, windproof 20~40 parts by weight and Yan Hu
25~30 parts by weight of rope.
2. Chinese medicine composition according to claim 1, which is characterized in that further include：
20~30 parts by weight of cushaw seedling, 20~40 parts by weight of day name essence, 15~25 parts by weight of storax, 20~30 parts by weight of cicada slough
With 15~20 parts by weight of Radix Isatidis.
3. Chinese medicine composition according to claim 2, which is characterized in that be made of following raw material components：
35 parts by weight of ginger, 25 parts by weight of Luzon fruit, 35 parts by weight of Radix Codonopsis, 25 parts by weight of Radix Astragali, 22 parts by weight of Chinese prickly ash, Radix Glycyrrhizae 26
Parts by weight, 20 parts by weight of Lappula echinata, 15 parts by weight of prepared rehmannia root, 30 parts by weight of American Ginseng, 35 parts by weight of styrax, 25 weight of cushaw seedling
Part, smart 30 parts by weight of 20 parts by weight of grass-leaved sweetflag, 16 parts by weight of RADIX CHUNAMINSHEN, day name, 25 parts by weight of mulberry fruit, 25 parts by weight of frutus cnidii,
18 parts by weight of Radix Isatidis, 16 parts by weight of Radix Notoginseng, 35 parts by weight of stiff silkworm, 25 parts by weight of sealwort, 25 parts by weight of cicada slough, 20 weight of storax
Measure part, 13 parts by weight of prepared fleece flower root, 25 parts by weight of centipede, 25 parts by weight of smilax, 12 parts by weight of root of Chinese trichosanthes, 35 weight of ganoderma lucidum
Part, 25 parts by weight of Rhizoma Gastrodiae, 28 parts by weight of 25 parts by weight of scorpio, windproof 30 parts by weight and corydalis tuber.
4. Chinese medicine composition according to claim 2, which is characterized in that be made of following raw material components：
40 parts by weight of ginger, 20 parts by weight of Luzon fruit, 40 parts by weight of Radix Codonopsis, 20 parts by weight of Radix Astragali, 25 parts by weight of Chinese prickly ash, Radix Glycyrrhizae 20
Parts by weight, 30 parts by weight of Lappula echinata, 15 parts by weight of prepared rehmannia root, 20 parts by weight of American Ginseng, 40 parts by weight of styrax, 20 weight of cushaw seedling
Part, smart 40 parts by weight of 30 parts by weight of grass-leaved sweetflag, 15 parts by weight of RADIX CHUNAMINSHEN, day name, 20 parts by weight of mulberry fruit, 30 parts by weight of frutus cnidii,
15 parts by weight of Radix Isatidis, 20 parts by weight of Radix Notoginseng, 30 parts by weight of stiff silkworm, 30 parts by weight of sealwort, 20 parts by weight of cicada slough, 25 weight of storax
Measure part, 10 parts by weight of prepared fleece flower root, 30 parts by weight of centipede, 20 parts by weight of smilax, 15 parts by weight of root of Chinese trichosanthes, 30 weight of ganoderma lucidum
Part, 30 parts by weight of Rhizoma Gastrodiae, 25 parts by weight of 20 parts by weight of scorpio, windproof 40 parts by weight and corydalis tuber.
5. the preparation method of any one of Claims 1 to 4 Chinese medicine composition, which is characterized in that include the following steps：
S101：Each raw material component is cleaned, dry after crush；Raw material components after the crushing are extracted using solvent,
Collect extracting solution；
S102：The thick paste that relative density is 1.15~1.35 when the extracting solution is condensed into 70 DEG C, obtains the Chinese traditional medicine composition
Object.
6. the preparation method of Chinese medicine composition according to claim 5, it is characterised in that：
The weight ratio of the raw material components and the solvent is 1：(5~30), the solvent are deionized water, ethyl alcohol or ethanol water
Solution, and each raw material component is crushed to 60~200 mesh.
7. the preparation method of Chinese medicine composition according to claim 6, it is characterised in that：
The mass percentage concentration of the ethanol water is 15%~20%.
8. the preparation method of Chinese medicine composition according to claim 5, it is characterised in that：
The condition of the extraction is：Refluxing extraction 5h~10h under conditions of temperature is 45 DEG C~65 DEG C, the number of the extraction
At least 1 time.
9. Claims 1 to 4 any one of them Chinese medicine composition is in preparing the drug and/or medicated premix for drug rehabilitation
Application.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN115702923A (en) * | 2021-08-04 | 2023-02-17 | 冉如玉 | Traditional Chinese medicine formula for regulating body functions |
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| CN106880796A (en) * | 2017-03-07 | 2017-06-23 | 贵州都匀市剑江药业有限公司 | Chinese medicine composition and its preparation method and application for treating tumour |
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| CN1330935A (en) * | 2000-06-28 | 2002-01-16 | 吕汉 | Drug-dropping Chinese patent medicine for improving immunity of human body itself |
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| CN106377738A (en) * | 2016-08-25 | 2017-02-08 | 广东赤帝生命科技有限公司 | Chinese medicinal composition for drug addiction rehabilitation and method for preparation of drug addiction rehabilitation oral solution from the same |
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