CN106880796A - Chinese medicine composition and its preparation method and application for treating tumour - Google Patents
Chinese medicine composition and its preparation method and application for treating tumour Download PDFInfo
- Publication number
- CN106880796A CN106880796A CN201710131224.XA CN201710131224A CN106880796A CN 106880796 A CN106880796 A CN 106880796A CN 201710131224 A CN201710131224 A CN 201710131224A CN 106880796 A CN106880796 A CN 106880796A
- Authority
- CN
- China
- Prior art keywords
- parts
- medicine composition
- chinese medicine
- tumour
- raw material
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/90—Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/234—Cnidium (snowparsley)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
- A61K36/428—Trichosanthes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Insects & Arthropods (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Chinese medicine composition the present invention relates to be used to treat tumour, including following parts by weight raw material：10 parts~15 parts of 15 parts~17 parts of sealwort, 22 parts~23 parts of RADIX POLYGONI MULTIFLORI PREPARATA, 24 parts~26 parts of mulberries, 3 parts~7 parts of cicada slough, 2 parts~8 parts of storax, 2 parts~8 parts of styrax, 2 parts~5 parts of stiff silkworm, 7 parts~10 parts of candolle pimpinella herb, 20 parts~25 parts of corydalis tuber, 25 parts~35 parts of smilax, 5 parts~15 parts of root of Chinese trichosanthes, 1 part~10 parts of frutus cnidii and Radix Glycyrrhizae.Of the invention easy to use for treating the Chinese medicine composition of tumour, evident in efficacy, clinic is promoted, with good commercial promise.
Description
Technical field
The invention belongs to the field of Chinese medicines, and in particular to a kind of Chinese medicine composition for treating tumour and preparation method thereof and
Using.
Background technology
Tumour refers to body under the effect of the various tumorigenesis factors, the neoformation that local organization hyperplasia is formed, because
Being in occupancy block-like protrusions, also referred to as neoplasm this neoformation more.According to neoplastic cell characteristics and the harmfulness to body
Degree, and tumour is divided into benign tumour and the major class of malignant tumour two.And the essential therapeutic arsenals of tumour except operation in addition to, still
It is radiation and chemotherapy.In most cases, using operation, chemoradiotherapy.The toxic and side effect of chemicotherapy knows from experience generation to people
Greatly infringement, the especially immune and hematopoietic cell to human body cause serious harm.Simultaneously as tumour cell can produce anti-medicine
Property, chemicotherapy means are difficult to thoroughly remove all of tumour cell in human body, especially malignant tumour.Therefore, chemicotherapy treatment
Afterwards, recurrence rate is very high.It is more difficult to be cured with chemicotherapy means after recurrence.Sb.'s illness took a turn for the worse after causing most tumors patient to be recurred arrives
Unmanageable degree and threat to life.
The content of the invention
It is an object of the present invention to propose a kind of Chinese medicine composition for treating tumour.
The Chinese medicine composition for treating tumour according to embodiments of the present invention, including following parts by weight raw material：It is yellow
15 parts~17 parts of essence, 22 parts~23 parts of RADIX POLYGONI MULTIFLORI PREPARATA, 24 parts~26 parts of mulberries, 3 parts~7 parts of cicada slough, 2 parts~8 parts of storax, rest in peace
Fragrant 2 parts~8 parts, 2 parts~5 parts of stiff silkworm, 7 parts~10 parts of candolle pimpinella herb, 20 parts~25 parts of corydalis tuber, 25 parts~35 parts of smilax,
10 parts~15 parts of 5 parts~15 parts of root of Chinese trichosanthes, 1 part~10 parts of frutus cnidii and Radix Glycyrrhizae.
Chinese medicine composition prepared by the inventive method has good inhibiting effect to tumour, and clinical observation shows, this
The Chinese medicine composition of inventive embodiments, effect is substantially, safe and convenient to use, is comfortable on after use, and patient medication complies with
Property is good.Chinese medicine composition for treating tumour of the invention, it is not necessary to complicated Primary Care regulation, treatment tumor effect reason
Want there is obvious social benefits and economic benefit.Chinese medicine composition prepared by the inventive method, its is evident in efficacy, clinic
Promote, with good commercial promise.
Further, the raw material of the above-mentioned Chinese medicine composition for treating tumour, including following parts by weight：Sealwort 16
Part, 22.2 parts of RADIX POLYGONI MULTIFLORI PREPARATA, 25 parts of mulberries, 5 parts of cicada slough, 4.5 parts of storax, 5 parts of styrax, 3.3 parts of stiff silkworm, candolle pimpinella herb 8.4
Part, 22.2 parts of corydalis tuber, 29.2 parts of smilax, 8.4 parts of root of Chinese trichosanthes, 5.55 parts of frutus cnidii and 11.1 parts of Radix Glycyrrhizae.
Further, the raw material of the above-mentioned Chinese medicine composition for treating tumour, including following parts by weight：Sealwort 15
Part, 23 parts of RADIX POLYGONI MULTIFLORI PREPARATA, 24 parts of mulberries, 7 parts of cicada slough, 2 parts of storax, 8 parts of styrax, 2 parts of stiff silkworm, 10 parts of candolle pimpinella herb, prolong recklessly
10 parts of 20 parts of rope, 35 parts of smilax, 5 parts of root of Chinese trichosanthes, 10 parts of frutus cnidii and Radix Glycyrrhizae.
Further, the raw material of the above-mentioned Chinese medicine composition for treating tumour, including following parts by weight：Sealwort 17
Part, 22 parts of RADIX POLYGONI MULTIFLORI PREPARATA, 26 parts of mulberries, 3 parts of cicada slough, 8 parts of storax, 2 parts of styrax, 5 parts of stiff silkworm, 7 parts of candolle pimpinella herb, corydalis tuber
15 parts of 25 parts, 25 parts of smilax, 15 parts of root of Chinese trichosanthes, 1 part of frutus cnidii and Radix Glycyrrhizae.
It is another object of the present invention to the preparation method for proposing the above-mentioned Chinese medicine composition for treating tumour.
The preparation method of the above-mentioned Chinese medicine composition for treating tumour, comprises the following steps：By the raw material according to
Above-mentioned parts by weight are weighed, then according to solid-liquid ratio 1000g：1L adds water, is heated to 70 DEG C~90 DEG C, is incubated 3h~5h,
Then cool the temperature to normal temperature and filter, collect filtrate, obtain the Chinese medicine composition for treating tumour.
Further, the aperture of the filter membrane for being used during filtering is 1 μm~10 μm.
The preparation method of the above-mentioned Chinese medicine composition for treating tumour, comprises the following steps：By the raw material according to
Above-mentioned parts by weight are weighed, and are then ground to powdery and are sieved, and collect the material after sieving, obtain described for treating tumour
Chinese medicine composition.
Further, a diameter of 1 μm~10 μm of the screen cloth.
It is another object of the present invention to propose above-mentioned Chinese medicine composition in preparing for tumor
Using.
It is another object of the present invention to propose above-mentioned Chinese medicine composition in preparing for treating ascites tumor medicine
Application.
Additional aspect of the invention and advantage will be set forth in part in the description, and will partly become from the following description
Obtain substantially, or recognized by practice of the invention.
Specific embodiment
Embodiments of the invention are described below in detail, the embodiment is exemplary, it is intended to for explaining the present invention, and
It is not considered as limiting the invention.
Experimental technique in following embodiments, unless otherwise specified, is conventional method.
Test material used in following embodiments, unless otherwise specified, is what is be commercially available from conventional reagent shop.
Quantitative test in following examples, is respectively provided with three repetitions and tests, and data are three average values of repetition experiment
Or mean+SD.
Sealwort used in following embodiments, RADIX POLYGONI MULTIFLORI PREPARATA, mulberries, cicada slough, storax, styrax, stiff silkworm, candolle pimpinella herb,
Corydalis tuber, smilax, root of Chinese trichosanthes, frutus cnidii and Radix Glycyrrhizae meet under each medicinal material of text of Chinese Pharmacopoeia (version in 2015)
Pertinent regulations.Before feeding intake, by identification, ingredients material object is consistent with title, and quality meets standard.
Embodiment 1
Embodiment 1 proposes a kind of Chinese medicine composition for treating tumour, including following parts by weight raw material：Sealwort
16 parts, 22.2 parts of RADIX POLYGONI MULTIFLORI PREPARATA, 25 parts of mulberries, 5 parts of cicada slough, 4.5 parts of storax, 5 parts of styrax, 3.3 parts of stiff silkworm, candolle pimpinella herb
11.1 parts of 8.4 parts, 22.2 parts of corydalis tuber, 29.2 parts of smilax, 8.4 parts of root of Chinese trichosanthes, 5.55 parts of frutus cnidii and Radix Glycyrrhizae.
The preparation method of the Chinese medicine composition for treating tumour of embodiment 1, comprises the following steps：The raw material is pressed
Weighed according to above-mentioned parts by weight, then according to solid-liquid ratio 1000g：1L adds water, is heated to 80 DEG C, 4h is incubated, then by temperature
Degree is down to normal temperature and is filtered, and the aperture of the filter membrane used during filtering is about 5 μm, collects filtrate, obtains described for treating tumour
Chinese medicine composition.
Embodiment 2
Embodiment 2 proposes a kind of Chinese medicine composition for treating tumour, including following parts by weight raw material：Sealwort
15 parts, 23 parts of RADIX POLYGONI MULTIFLORI PREPARATA, 24 parts of mulberries, 7 parts of cicada slough, 2 parts of storax, 8 parts of styrax, 2 parts of stiff silkworm, 10 parts of candolle pimpinella herb, prolong
10 parts of 20 parts of Hu rope, 35 parts of smilax, 5 parts of root of Chinese trichosanthes, 10 parts of frutus cnidii and Radix Glycyrrhizae.
The preparation method of the Chinese medicine composition for treating tumour of embodiment 2, comprises the following steps：
The raw material is weighed according to above-mentioned parts by weight, powdery is then ground to and is sieved, collect the material after sieving,
The diameter of screen cloth is about 5 μm, obtains the Chinese medicine composition for treating tumour.
Embodiment 3
Embodiment 3 proposes a kind of Chinese medicine composition for treating tumour, including following parts by weight raw material：Sealwort
17 parts, 22 parts of RADIX POLYGONI MULTIFLORI PREPARATA, 26 parts of mulberries, 3 parts of cicada slough, 8 parts of storax, 2 parts of styrax, 5 parts of stiff silkworm, 7 parts of candolle pimpinella herb, prolong recklessly
15 parts of 25 parts of rope, 25 parts of smilax, 15 parts of root of Chinese trichosanthes, 1 part of frutus cnidii and Radix Glycyrrhizae.
The preparation method of the Chinese medicine composition for treating tumour of embodiment 3, comprises the following steps：The raw material is pressed
Weighed according to above-mentioned parts by weight, then according to solid-liquid ratio 1000g：1L adds water, is heated to 85 DEG C, 5h is incubated, then by temperature
Degree is down to normal temperature and is filtered, and the aperture of the filter membrane used during filtering is about 8 μm, collects filtrate, obtains described for treating tumour
Chinese medicine composition.
Comparative example 1
Comparative example 1 is differed only in embodiment 1, the raw material of the Chinese medicine composition for treating tumour of comparative example 1
Do not include frutus cnidii, candolle pimpinella herb and storax, remaining raw material all same, its preparation method is same as Example 1 with parameter.
Comparative example 2
Comparative example 2 is differed only in embodiment 2, the raw material of the Chinese medicine composition for treating tumour of comparative example 2
Do not include stiff silkworm, styrax and root of Chinese trichosanthes, remaining raw material all same, its preparation method is same as Example 2 with parameter.
In order to evaluate effect of each embodiment and each comparative example, following experiment is carried out：
First, toxicity test
The small white mouse 200 (each 100 of male and female) that body weight is 18~22g is selected, is divided into 5 groups, every group of each 20 of male and female, little Bai
Mouse back unhairing exposes exocuticle, unhairing scope 2cm × 2cm, and first group to third component is not smeared the embodiment of the present invention 1 to reality
Apply the Chinese medicine composition that example 3 is prepared, the 4th group to BSA is not smeared comparative example of the present invention 1 and comparative example 2 is prepared into
The Chinese medicine composition for arriving, dosage is 5g, successive administration 30 days.When during administration and 1 week after drug withdrawal, observation white mouse growth shape
State and activity and diet, identification hematology, blood biochemical analysis, organ tissue structure and routine urinalysis etc..Result finds all little Bai
Mouse health existence, it is without any side effects；Anatomic observation blood picture, liver function, each organs and tissues state, with normal small white mouse ratio
Compared with indifference.It is demonstrated experimentally that the Chinese medicine composition that the present invention is provided is nontoxic, drug safety reliability.
2nd, rat experiment：Ascites tumor experiment (Ascitic Tumor Cells are purchased from Shanghai Gai Ning bio tech ltd)
Healthy rat 120 is randomly selected, weight 20g~25g is randomly divided into 6 groups, every group 20.
The S-180 Ascitic Tumor Cells that will be frozen in liquid nitrogen container are taken out, recovery, and in vitro culture is added in RPM11640
Volume fraction is 0.1 calf serum, 100,000 units of penicillin/L, streptomysin 100mg/L, and monolayer cultivation is in CO2Constant-temperature incubation
In case, cell is Epithelial adherent growth, is passed on 1 time per couple of days, and growth period cell of taking the logarithm is used to test.Use volume fraction
For the RPM11640 nutrient solutions diluting cells of 0.1 calf serum extremely contain knurl 1 × 1010L, in rat right lower abdomen hypodermic injection S-
180 Ascitic Tumor Cells 5,000,000, make rat abdomen produce tumour.
Gastric infusion since rat inoculation Ascitic Tumor Cells the 3rd day.Respectively by 1~embodiment of embodiment 3 and contrast
Rat of the Chinese medicine composition that example 1 and comparative example 2 are obtained accordingly to first group~the 5th group carries out gavage, once a day, continuously
30 days, if the Chinese medicine composition of liquid, each 20mL；If the Chinese medicine composition of powder, each 20mg.6th group of rat be
Blank control group, the physiological saline of gavage equivalent, continuous 30 days.
All rats are dissected after being discontinued one week, extracts measurement of tumor knurl weight, tumor suppression is calculated by formula (1)
Rate：
Tumor control rate=(the average average knurl quality of knurl quality-administration group of control group) average knurl quality of/control group ×
100%.Formula (1)
Measurement result is shown in Table 1.
Table 1：Rat tumor measurement result
It can be seen from Table 1 that, compare each embodiment and comparative example, the tumour in the rat body of 1~embodiment of embodiment 3
Average weight in 3g or so, and the average weight of the tumour of the rat of comparative example is in 7g or so, and continuous gavage embodiment 1
The Chinese medicine composition one month of~embodiment 3 afterwards, there is partial rat cases of complete remission, illustrates prepared by the inventive method
Chinese medicine composition has good inhibiting effect to tumour.
To sum up, the Chinese medicine composition of the embodiment of the present invention has good inhibiting effect to rat ascites oncocyte, and part is big
The cases of complete remission of mouse, effect is significant.And clinical observation shows, the Chinese medicine composition of the embodiment of the present invention does not find bad
Reaction, using safety, treatment patient's reaction medicine is easy to use, is comfortable on after use, and patient medication's compliance is good.This
The Chinese medicine composition medication for treating tumour of invention is simple and easy to apply, it is not necessary to complicated Primary Care regulation, treats tumour
Effect is preferable, there is obvious social benefits and economic benefit.
To sum up, the Chinese medicine composition prepared by the inventive method has good inhibiting effect to tumour, and its is evident in efficacy, value
Clinical expansion is obtained, with good commercial promise.
In the description of this specification, reference term " one embodiment ", " some embodiments ", " example ", " specifically show
The description of example " or " some examples " etc. means to combine specific features, structure, material or spy that the embodiment or example are described
Point is contained at least one embodiment of the invention or example.In this manual, to the schematic representation of above-mentioned term not
Identical embodiment or example must be directed to.And, the specific features of description, structure, material or feature can be with office
Combined in an appropriate manner in one or more embodiments or example.Additionally, in the case of not conflicting, the skill of this area
Art personnel can be tied the feature of the different embodiments or example described in this specification and different embodiments or example
Close and combine.
Although embodiments of the invention have been shown and described above, it is to be understood that above-described embodiment is example
Property, it is impossible to limitation of the present invention is interpreted as, one of ordinary skill in the art within the scope of the invention can be to above-mentioned
Embodiment is changed, changes, replacing and modification.
Claims (10)
1. a kind of Chinese medicine composition for treating tumour, it is characterised in that the raw material including following parts by weight：15 parts of sealwort
~17 parts, 22 parts~23 parts of RADIX POLYGONI MULTIFLORI PREPARATA, 24 parts~26 parts of mulberries, 3 parts~7 parts of cicada slough, 2 parts~8 parts of storax, 2 parts of styrax
~8 parts, 2 parts~5 parts of stiff silkworm, 7 parts~10 parts of candolle pimpinella herb, 20 parts~25 parts of corydalis tuber, 25 parts~35 parts of smilax, root of Chinese trichosanthes
10 parts~15 parts of 5 parts~15 parts, 1 part~10 parts of frutus cnidii and Radix Glycyrrhizae.
2. the Chinese medicine composition for treating tumour according to claim 1, it is characterised in that including following parts by weight
Raw material：16 parts of sealwort, 22.2 parts of RADIX POLYGONI MULTIFLORI PREPARATA, 25 parts of mulberries, 5 parts of cicada slough, 4.5 parts of storax, 5 parts of styrax, stiff silkworm 3.3
Part, 8.4 parts of candolle pimpinella herb, 22.2 parts of corydalis tuber, 29.2 parts of smilax, 8.4 parts of root of Chinese trichosanthes, 5.55 parts of frutus cnidii and Radix Glycyrrhizae 11.1
Part.
3. the Chinese medicine composition for treating tumour according to claim 1, it is characterised in that including following parts by weight
Raw material：15 parts of sealwort, 23 parts of RADIX POLYGONI MULTIFLORI PREPARATA, 24 parts of mulberries, 7 parts of cicada slough, 2 parts of storax, 8 parts of styrax, 2 parts of stiff silkworm, apricot leaf
10 parts of windproof 10 parts, 20 parts of corydalis tuber, 35 parts of smilax, 5 parts of root of Chinese trichosanthes, 10 parts of frutus cnidii and Radix Glycyrrhizae.
4. the Chinese medicine composition for treating tumour according to claim 1, it is characterised in that including following parts by weight
Raw material：17 parts of sealwort, 22 parts of RADIX POLYGONI MULTIFLORI PREPARATA, 26 parts of mulberries, 3 parts of cicada slough, 8 parts of storax, 2 parts of styrax, 5 parts of stiff silkworm, apricot leaf
15 parts of windproof 7 parts, 25 parts of corydalis tuber, 25 parts of smilax, 15 parts of root of Chinese trichosanthes, 1 part of frutus cnidii and Radix Glycyrrhizae.
5. the preparation method of the Chinese medicine composition for treating tumour according to any one of Claims 1 to 4, its feature exists
In comprising the following steps：The raw material is weighed according to above-mentioned parts by weight, then according to solid-liquid ratio 1000g：1L adds water,
70 DEG C~90 DEG C are heated to, 3h~5h is incubated, normal temperature are then cooled the temperature to and is filtered, collect filtrate, obtain described being used for
Treat the Chinese medicine composition of tumour.
6. the preparation method for treating the Chinese medicine composition of tumour according to claim 5, it is characterised in that during filtering
The aperture of the filter membrane for using is 1 μm~10 μm.
7. the preparation method of the Chinese medicine composition for treating tumour according to any one of Claims 1 to 4, its feature exists
In comprising the following steps：The raw material is weighed according to above-mentioned parts by weight, powdery is then ground to and is sieved, collect sieving
Material afterwards, obtains the Chinese medicine composition for treating tumour.
8. the preparation method for treating the Chinese medicine composition of tumour according to claim 7, it is characterised in that the sieve
A diameter of 1 μm~10 μm of net.
9. application of the Chinese medicine composition according to any one of Claims 1 to 4 in preparing for tumor.
10. the Chinese medicine composition according to any one of Claims 1 to 4 is preparing answering in being used to treat ascites tumor medicine
With.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710131224.XA CN106880796A (en) | 2017-03-07 | 2017-03-07 | Chinese medicine composition and its preparation method and application for treating tumour |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710131224.XA CN106880796A (en) | 2017-03-07 | 2017-03-07 | Chinese medicine composition and its preparation method and application for treating tumour |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106880796A true CN106880796A (en) | 2017-06-23 |
Family
ID=59179562
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710131224.XA Withdrawn CN106880796A (en) | 2017-03-07 | 2017-03-07 | Chinese medicine composition and its preparation method and application for treating tumour |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106880796A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108379541A (en) * | 2018-05-18 | 2018-08-10 | 重庆跃龙生物制药有限公司 | Chinese medicine composition and preparation method thereof for drug rehabilitation |
| CN108420977A (en) * | 2018-05-14 | 2018-08-21 | 重庆跃龙生物制药有限公司 | Chinese medicine composition and its preparation method and application for treating cancer |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1330935A (en) * | 2000-06-28 | 2002-01-16 | 吕汉 | Drug-dropping Chinese patent medicine for improving immunity of human body itself |
| CN101450165A (en) * | 2007-11-29 | 2009-06-10 | 北京久久方元保健品经销有限公司 | Anti-cancer traditional Chinese medicine compound ganoderma preparation and preparation method thereof |
-
2017
- 2017-03-07 CN CN201710131224.XA patent/CN106880796A/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1330935A (en) * | 2000-06-28 | 2002-01-16 | 吕汉 | Drug-dropping Chinese patent medicine for improving immunity of human body itself |
| CN101450165A (en) * | 2007-11-29 | 2009-06-10 | 北京久久方元保健品经销有限公司 | Anti-cancer traditional Chinese medicine compound ganoderma preparation and preparation method thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108420977A (en) * | 2018-05-14 | 2018-08-21 | 重庆跃龙生物制药有限公司 | Chinese medicine composition and its preparation method and application for treating cancer |
| CN108379541A (en) * | 2018-05-18 | 2018-08-10 | 重庆跃龙生物制药有限公司 | Chinese medicine composition and preparation method thereof for drug rehabilitation |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN106880796A (en) | Chinese medicine composition and its preparation method and application for treating tumour | |
| CN104095234B (en) | A kind of functional food nursing one's health fatty liver | |
| JP2019535833A (en) | Traditional Chinese medicine composition for tumor treatment and its production method and use | |
| CN105919890B (en) | A kind of oil control and acne removal composition and preparation method and application | |
| CN109674866A (en) | A kind of anti-human primary gastrointestinal cancers pharmaceutical composition, preparation method and applications | |
| CN105664140A (en) | Glycopeptide composition as well as preparation method and application thereof | |
| CN108310050A (en) | Blue or green money willow extract and its preparation and hypoglycemic application | |
| CN103690574A (en) | Poria-containing traditional Chinese medicine combination for enhancing immunity and preparation method of poria-containing traditional Chinese medicine combination | |
| CN109172599A (en) | Microcapsule formulation and preparation method thereof for preventing and treating chicken leucocyte protozoon | |
| CN101829272B (en) | Traditional Chinese medicine composition for treating diabetes mellitus and preparation method thereof | |
| CN105343260B (en) | The drug for treating chronic ulcerative colitis | |
| CN106214853A (en) | A kind of for promoting the Chinese medicine composition of diabetes wound healing | |
| CN101181440B (en) | Chinese medicine composition for curing hemopathy as well as preparation method and usage thereof | |
| CN105596674A (en) | Black garlic extract and application thereof in preventing and curing breast cancer | |
| CN109248269A (en) | A kind of traditional Chinese medicine for outer use for treating hyperplasia of mammary glands | |
| CN108245608A (en) | A kind of effective Chinese herbal medicine for inhibiting tumour and preparation method thereof | |
| CN102872332A (en) | Bao yaowang medicinal and edible Chinese medicinal herb composition for treating blood diseases and preparation method and application thereof | |
| CN105106770B (en) | A kind of Chinese medicine composition and its preparation method and application as antitumor adjuvant | |
| CN107362205A (en) | Chinese medicine composition for treating scald and its preparation method and application | |
| CN108014260A (en) | A kind of anti-tumor compound wheat deer stilbene Ren Can Spoon preparation methods | |
| CN108651861B (en) | Antioxidant curcumin duck blood bean curd and preparation method thereof | |
| CN104887858A (en) | Traditional Chinese medicine preparation for treating hepatitis of Chinese softshell turtles and preparation method of traditional Chinese medicine preparation | |
| CN106075034A (en) | A kind of treat Chinese medicine preparation of nephrotoxicity and its preparation method and application after chemicotherapy | |
| Hameed et al. | Impact of Natural Plant on characterization of Nano Biomaterial for Blood Toxicology | |
| CN109432297A (en) | Recoon dog oral solution and preparation method thereof and purposes |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20170623 |
|
| WW01 | Invention patent application withdrawn after publication |