CN108371247A - A kind of compound probiotic improving piglet survival rate - Google Patents
A kind of compound probiotic improving piglet survival rate Download PDFInfo
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- CN108371247A CN108371247A CN201711112322.5A CN201711112322A CN108371247A CN 108371247 A CN108371247 A CN 108371247A CN 201711112322 A CN201711112322 A CN 201711112322A CN 108371247 A CN108371247 A CN 108371247A
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- 239000006041 probiotic Substances 0.000 title claims abstract description 45
- 235000018291 probiotics Nutrition 0.000 title claims abstract description 45
- 150000001875 compounds Chemical class 0.000 title claims abstract description 32
- 230000000529 probiotic effect Effects 0.000 title claims abstract description 28
- 230000004083 survival effect Effects 0.000 title claims abstract description 20
- 241000894006 Bacteria Species 0.000 claims abstract description 18
- 230000001580 bacterial effect Effects 0.000 claims abstract description 8
- 230000003053 immunization Effects 0.000 claims abstract description 6
- 241000194031 Enterococcus faecium Species 0.000 claims description 14
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 claims description 14
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 14
- 239000002994 raw material Substances 0.000 claims description 14
- 241000193749 Bacillus coagulans Species 0.000 claims description 7
- 241000194108 Bacillus licheniformis Species 0.000 claims description 7
- 244000063299 Bacillus subtilis Species 0.000 claims description 7
- 235000014469 Bacillus subtilis Nutrition 0.000 claims description 7
- 244000025254 Cannabis sativa Species 0.000 claims description 7
- 241000193171 Clostridium butyricum Species 0.000 claims description 7
- 241000186660 Lactobacillus Species 0.000 claims description 7
- 240000001046 Lactobacillus acidophilus Species 0.000 claims description 7
- 235000013956 Lactobacillus acidophilus Nutrition 0.000 claims description 7
- 241000191998 Pediococcus acidilactici Species 0.000 claims description 7
- 239000002253 acid Substances 0.000 claims description 7
- 229940054340 bacillus coagulans Drugs 0.000 claims description 7
- 238000009833 condensation Methods 0.000 claims description 7
- 230000005494 condensation Effects 0.000 claims description 7
- 235000014655 lactic acid Nutrition 0.000 claims description 7
- 239000004310 lactic acid Substances 0.000 claims description 7
- 229940039696 lactobacillus Drugs 0.000 claims description 7
- 229940039695 lactobacillus acidophilus Drugs 0.000 claims description 7
- 239000000203 mixture Substances 0.000 claims description 7
- 239000000654 additive Substances 0.000 claims description 6
- 230000000996 additive effect Effects 0.000 claims description 6
- 238000002360 preparation method Methods 0.000 claims description 6
- 239000000284 extract Substances 0.000 claims description 5
- 239000002674 ointment Substances 0.000 claims description 5
- 206010012735 Diarrhoea Diseases 0.000 abstract description 7
- 230000000968 intestinal effect Effects 0.000 abstract description 7
- 230000036039 immunity Effects 0.000 abstract description 6
- 210000004347 intestinal mucosa Anatomy 0.000 abstract description 4
- 206010028140 Mucous stools Diseases 0.000 abstract description 3
- 208000001848 dysentery Diseases 0.000 abstract description 3
- 208000035240 Disease Resistance Diseases 0.000 abstract description 2
- 108060003951 Immunoglobulin Proteins 0.000 abstract description 2
- 239000000427 antigen Substances 0.000 abstract description 2
- 102000036639 antigens Human genes 0.000 abstract description 2
- 108091007433 antigens Proteins 0.000 abstract description 2
- 230000009286 beneficial effect Effects 0.000 abstract description 2
- 238000010241 blood sampling Methods 0.000 abstract description 2
- 238000006243 chemical reaction Methods 0.000 abstract description 2
- 231100000749 chronicity Toxicity 0.000 abstract description 2
- 230000006353 environmental stress Effects 0.000 abstract description 2
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract description 2
- 230000036541 health Effects 0.000 abstract description 2
- 230000001900 immune effect Effects 0.000 abstract description 2
- 102000018358 immunoglobulin Human genes 0.000 abstract description 2
- 244000005700 microbiome Species 0.000 abstract description 2
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- 230000000405 serological effect Effects 0.000 abstract description 2
- 239000013589 supplement Substances 0.000 abstract description 2
- 241000282898 Sus scrofa Species 0.000 description 8
- 201000010099 disease Diseases 0.000 description 8
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 8
- 239000003814 drug Substances 0.000 description 5
- 230000002401 inhibitory effect Effects 0.000 description 4
- 235000016709 nutrition Nutrition 0.000 description 4
- 230000003115 biocidal effect Effects 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 230000035764 nutrition Effects 0.000 description 3
- 241001533384 Circovirus Species 0.000 description 2
- 241000588724 Escherichia coli Species 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 2
- 238000009395 breeding Methods 0.000 description 2
- 230000001488 breeding effect Effects 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000002708 enhancing effect Effects 0.000 description 2
- 235000021050 feed intake Nutrition 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
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- 206010059866 Drug resistance Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 241000607142 Salmonella Species 0.000 description 1
- 206010039438 Salmonella Infections Diseases 0.000 description 1
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- 241000282887 Suidae Species 0.000 description 1
- 230000003698 anagen phase Effects 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
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- 244000144974 aquaculture Species 0.000 description 1
- 230000037444 atrophy Effects 0.000 description 1
- 208000010643 digestive system disease Diseases 0.000 description 1
- 239000002158 endotoxin Substances 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 210000004602 germ cell Anatomy 0.000 description 1
- 230000037308 hair color Effects 0.000 description 1
- 210000004251 human milk Anatomy 0.000 description 1
- 235000020256 human milk Nutrition 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 231100000417 nephrotoxicity Toxicity 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 235000013406 prebiotics Nutrition 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 206010039447 salmonellosis Diseases 0.000 description 1
- 208000013223 septicemia Diseases 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
- A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
- A23K20/147—Polymeric derivatives, e.g. peptides or proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/60—Feeding-stuffs specially adapted for particular animals for weanlings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/742—Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
- A61K36/064—Saccharomycetales, e.g. baker's yeast
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/113—Acidophilus
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/41—Pediococcus
- A23V2400/413—Acidilactici
Abstract
The invention discloses a kind of compound probiotics improving piglet survival rate, are related to microorganisms technical field, it is made of probiotics and birds immune globulin IgY；This compound probiotic can reduce piglet Huang, dysentery characterized by white mucous stool and other intestinal bacterials are had loose bowels, the incidence of diarrhea, improve piglet survival ratio, promote the development of piglet immunological organ, improve the immunity and disease resistance of piglet, reduce incidence, supplement beneficial bacteria of intestinal tract, adjust the intestinal flora environment of piglet, enhance resistance of the piglet to environmental stress, improve the chronicity and stability of piglet Population Health, protect intestinal mucosa and intestinal villus normal development, improve nutrient absorption capability, using birds immune globulin IgY without blood sampling, only the egg that immune hen is given birth to, which need to be collected, can be obtained antibody, the uniform specific IgY of a large amount of quality had both been can get using a small amount of antigen Immunizing Birds, it will not occur to intersect serological reaction between birds IgY and mammalian immunoglobulin.
Description
Technical field:
The present invention relates to microorganisms technical field, specifically a kind of compound probiotic improving piglet survival rate.
Background technology:
The growth phase of pig is divided into piglet, child care pig and growing and fattening pigs, but the piglet stage is easiest to by all kinds of pathogen invasions, is pig
In the group's death rate highest stage in life, account for about 80% or so of the entire swinery death rate；Piglet is due to self immune system
Not yet develop perfect, premunition is poor, therefore easily infects inhibitive ability of immunity disease and son as caused by swine fever, circovirus etc.
The disease of digestive systems such as pig Huang, dysentery characterized by white mucous stool；Inhibitive ability of immunity disease caused by swine fever, circovirus etc. is always to endanger China at present
One of principal disease of pig breeding industry, and growing in intensity, also more especially for piglet harmfulness bigger, the caused death rate
Height causes serious economic loss to pig breeding industry；After weaned piglet, changed to eat the feed of solid by eating breast milk, thus pole
Intestinal mucosa easy to wear causes the Villus atrophy of intestinal mucosa, and nutritional ingredient must be absorbed by villus in small intestine, therefore nutrition
Ingredient cannot be digested and assimilated well, is caused enteral nutrition fermentation of materials, is upset normal intestinal flora environment, usually be caused tight
The Escherichia coli of weight, salmonella infection, lead to intractable diarrhea；Escherichia coli, salmonella generate intestines in metabolic process
Road endotoxin, easily further causes septicemia, aggravates the death of piglet.
Currently, it is seldom for preventing the medicine of inhibitive ability of immunity disease on veterinary clinic, and effect is not satisfactory, it is difficult to full
Foot is clinical to be needed；Antibiotic, sulfa drugs are generally used in terms of controlling diarrhea, due to long-term abuse of antibiotics, sulfamido
Drug so that drug resistance is generated to many bacterial strains, such dosage greatly increases, and the enhancing of liver renal toxicity not only increases use
Medicine cost, and also add the harm of antibiotic residue and toxic side effect to human body；In order to solve to be immunized on veterinary clinic
Inhibition disease and diarrhea class disease, are also had and are prevented using Chinese medicine preparation, but mostly powder, smell is big, and dosage is big, very
Difficulty is administered to Piglet by Oral, and there are poor bioavailabilities, and medicinal material is caused to waste, the undesirable situation of therapeutic effect.
Invention content:
The purpose of the present invention is to solve above-mentioned problems, and inhibitive ability of immunity disease is prevented using compound probiotic,
A kind of compound probiotic improving piglet survival rate is provided.
The technical problem to be solved in the present invention is realized by following scheme：It is a kind of to improve the compound prebiotic of piglet survival rate
Bacterium, it is made of probiotics and birds immune globulin IgY；Its raw material proportioning be Yi Sheng Jun ︰ birds immune globulin IgY=1~
6 ︰ 1~2；
The probiotics is by clostridium butyricum, lactobacillus acidophilus, Pediococcus acidilactici, bacillus licheniformis, bacillus subtilis, wine
Brewer yeast bacterium, bacillus coagulans, enterococcus faecium composition, raw material proportioning are the thermophilic sour lactobacillus ︰ lactic acid sheet balls of fourth acid shuttle bacterium ︰
Enterococcus faecium=5 Jun ︰ Di clothing Ya spore Gan Jun ︰ Ku grass Ya spore Gan Jun ︰ Niang brewer yeast Jun ︰ condensation Ya spore Gan Jun ︰~15 ︰, 25~50 ︰ 25
1~5 ︰ of~50 ︰ 5~15 ︰, 1~5 ︰, 1~5 ︰ 1~5；
The birds immune globulin IgY extracts in collecting the egg that immunizing birds are given birth to；
Described compound probiotic is ointment preparation, and the viable count of each bacterial strain is not less than 1*1010cfu/g；
Described compound probiotic can directly use the syringe of needleless or special oral administration device to realize, may further conduct
Feed addictive uses, and the additive amount in feed is 0.1%~0.3%, preferably 0.2%.
As a result of above technical scheme, preferably realize its goal of the invention, this raising piglet survival rate it is compound
Probiotics can reduce piglet yellow, dysentery characterized by white mucous stool and other intestinal bacterials have loose bowels, the incidence of diarrhea, improve piglet survival ratio, promote
The development of piglet immunological organ improves the immunity and disease resistance of piglet, reduces incidence, supplements beneficial bacteria of intestinal tract, adjustment
The intestinal flora environment of piglet, enhancing piglet improve the chronicity and stabilization of piglet Population Health to the resistance of environmental stress
Property, intestinal mucosa and intestinal villus normal development are protected, nutrient absorption capability is improved.Promote piglet nutrition to absorb, improves piglet and increase day by day
Weight, shortening marketing time, reduction aquaculture cost, improvement cultivation hygienic conditions, excrement is fine and smooth, shapes, and reduction excrement is smelly, purifies piglet
Growing environment reduces predisposing factors, hence it is evident that improves suckling piglet feed intake, feed intake improves 10-25% after feeding 3 days, improves hair
The color colour of skin, the colour of skin is ruddy after feeding 7 days, and hair color is bright, reduces or substitute feeding antibiotic, production safety product；Use birds
For immune globulin IgY without blood sampling, only need to collect the egg that immune hen is given birth to can be obtained antibody, be exempted from using a small amount of antigen
Epidemic disease birds both can get the uniform specific IgY of a large amount of quality, differ greatly since distance occurs for germline, birds IgY and the food in one's mouth
It will not occur to intersect serological reaction between newborn animal immune globulin.
Specific implementation mode:
Invention content is described further with reference to embodiment：
Embodiment 1:
By invention content it is found that a kind of compound probiotic improving piglet survival rate, it is by probiotics and birds immunoglobulin
IgY is formed；Its raw material proportioning is the ︰ 1~2 of Yi Sheng Jun ︰ birds immune globulin IgY=1~6；
The probiotics is by clostridium butyricum, lactobacillus acidophilus, Pediococcus acidilactici, bacillus licheniformis, bacillus subtilis, wine
Brewer yeast bacterium, bacillus coagulans, enterococcus faecium composition, raw material proportioning are the thermophilic sour lactobacillus ︰ lactic acid sheet balls of fourth acid shuttle bacterium ︰
Enterococcus faecium=5 Jun ︰ Di clothing Ya spore Gan Jun ︰ Ku grass Ya spore Gan Jun ︰ Niang brewer yeast Jun ︰ condensation Ya spore Gan Jun ︰~15 ︰, 25~50 ︰ 25
1~5 ︰ of~50 ︰ 5~15 ︰, 1~5 ︰, 1~5 ︰ 1~5；
The birds immune globulin IgY extracts in collecting the egg that immunizing birds are given birth to；
Described compound probiotic is ointment preparation, and the viable count of each bacterial strain is not less than 1*1010cfu/g；
Described compound probiotic can directly use the syringe of needleless or special oral administration device to realize, may further conduct
Feed addictive uses, and the additive amount in feed is 0.1%~0.3%, preferably 0.2%.
Embodiment 2:
By invention content it is found that a kind of compound probiotic improving piglet survival rate, it is by probiotics and birds immunoglobulin
IgY is formed；Its raw material proportioning is the ︰ 2 of Yi Sheng Jun ︰ birds immune globulin IgY=6；
The probiotics is by clostridium butyricum, lactobacillus acidophilus, Pediococcus acidilactici, bacillus licheniformis, bacillus subtilis, wine
Brewer yeast bacterium, bacillus coagulans, enterococcus faecium composition, raw material proportioning are the thermophilic sour lactobacillus ︰ lactic acid sheet balls of fourth acid shuttle bacterium ︰
Jun ︰ Di clothing Ya spore Gan Jun ︰ Ku grass Ya spore Gan Jun ︰ Niang brewer yeast Jun ︰ condensation Ya spore Gan Jun ︰ enterococcus faecium=8 ︰, 28 ︰, 28 ︰, 10 ︰, 4 ︰, 4 ︰
3 ︰ 2；
The birds immune globulin IgY extracts in collecting the egg that immunizing birds are given birth to；
Described compound probiotic is ointment preparation, and the viable count of each bacterial strain is not less than 1*1010cfu/g；
Described compound probiotic can directly use the syringe of needleless or special oral administration device to realize, may further conduct
Feed addictive uses, and the additive amount in feed is 0.2%.
Embodiment 3:
By invention content it is found that a kind of compound probiotic improving piglet survival rate, it is by probiotics and birds immunoglobulin
IgY is formed；Its raw material proportioning is the ︰ 1 of Yi Sheng Jun ︰ birds immune globulin IgY=5；
The probiotics is by clostridium butyricum, lactobacillus acidophilus, Pediococcus acidilactici, bacillus licheniformis, bacillus subtilis, wine
Brewer yeast bacterium, bacillus coagulans, enterococcus faecium composition, raw material proportioning are the thermophilic sour lactobacillus ︰ lactic acid sheet balls of fourth acid shuttle bacterium ︰
Jun ︰ Di clothing Ya spore Gan Jun ︰ Ku grass Ya spore Gan Jun ︰ Niang brewer yeast Jun ︰ condensation Ya spore Gan Jun ︰ enterococcus faecium=10 ︰, 30 ︰, 30 ︰, 12 ︰, 3 ︰
3 ︰, 4 ︰ 2；
The birds immune globulin IgY extracts in collecting the egg that immunizing birds are given birth to；
Described compound probiotic is ointment preparation, and the viable count of each bacterial strain is not less than 1*1010cfu/g；
Described compound probiotic can directly use the syringe of needleless or special oral administration device to realize, may further conduct
Feed addictive uses, and the additive amount in feed is 0.2%.
Claims (7)
1. a kind of compound probiotic improving piglet survival rate, it is characterized in that it is by probiotics and birds immune globulin IgY group
At；Its raw material proportioning is the ︰ 1~2 of Yi Sheng Jun ︰ birds immune globulin IgY=1~6；
The probiotics is by clostridium butyricum, lactobacillus acidophilus, Pediococcus acidilactici, bacillus licheniformis, bacillus subtilis, wine
Brewer yeast bacterium, bacillus coagulans, enterococcus faecium composition, raw material proportioning are the thermophilic sour lactobacillus ︰ lactic acid sheet balls of fourth acid shuttle bacterium ︰
Enterococcus faecium=5 Jun ︰ Di clothing Ya spore Gan Jun ︰ Ku grass Ya spore Gan Jun ︰ Niang brewer yeast Jun ︰ condensation Ya spore Gan Jun ︰~15 ︰, 25~50 ︰ 25
1~5 ︰ of~50 ︰ 5~15 ︰, 1~5 ︰, 1~5 ︰ 1~5.
2. it is according to claim 1 it is a kind of improve piglet survival rate compound probiotic, it is characterized in that it by probiotics with
Birds immune globulin IgY forms；Its raw material proportioning is the ︰ 2 of Yi Sheng Jun ︰ birds immune globulin IgY=6；
The probiotics is by clostridium butyricum, lactobacillus acidophilus, Pediococcus acidilactici, bacillus licheniformis, bacillus subtilis, wine
Brewer yeast bacterium, bacillus coagulans, enterococcus faecium composition, raw material proportioning are the thermophilic sour lactobacillus ︰ lactic acid sheet balls of fourth acid shuttle bacterium ︰
Jun ︰ Di clothing Ya spore Gan Jun ︰ Ku grass Ya spore Gan Jun ︰ Niang brewer yeast Jun ︰ condensation Ya spore Gan Jun ︰ enterococcus faecium=8 ︰, 28 ︰, 28 ︰, 10 ︰, 4 ︰, 4 ︰
3 ︰ 2.
3. it is according to claim 1 it is a kind of improve piglet survival rate compound probiotic, it is characterized in that it by probiotics with
Birds immune globulin IgY forms；Its raw material proportioning is the ︰ 1 of Yi Sheng Jun ︰ birds immune globulin IgY=5；
The probiotics is by clostridium butyricum, lactobacillus acidophilus, Pediococcus acidilactici, bacillus licheniformis, bacillus subtilis, wine
Brewer yeast bacterium, bacillus coagulans, enterococcus faecium composition, raw material proportioning are the thermophilic sour lactobacillus ︰ lactic acid sheet balls of fourth acid shuttle bacterium ︰
Jun ︰ Di clothing Ya spore Gan Jun ︰ Ku grass Ya spore Gan Jun ︰ Niang brewer yeast Jun ︰ condensation Ya spore Gan Jun ︰ enterococcus faecium=10 ︰, 30 ︰, 30 ︰, 12 ︰, 3 ︰
3 ︰, 4 ︰ 2；
The compound probiotic of a kind of raising piglet survival rate according to claim 1,2,3, it is characterized in that the birds
Immune globulin IgY extracts in collecting the egg that immunizing birds are given birth to.
4. the compound probiotic of a kind of raising piglet survival rate according to claim 1,2,3, it is characterized in that described should
Compound probiotic is ointment preparation, and the viable count of each bacterial strain is not less than 1*1010cfu/g.
5. the compound probiotic of a kind of raising piglet survival rate according to claim 1,2,3, it is characterized in that described should
Compound probiotic can directly use the syringe of needleless or special oral administration device to realize.
6. the compound probiotic of a kind of raising piglet survival rate according to claim 1,2,3, it is characterized in that the compound benefit
Raw bacterium can use as feed addictive, and the additive amount in feed is 0.1%~0.3%.
7. a kind of compound probiotic improving piglet survival rate according to claim 7, it is characterized in that the compound probiotic
It can be used as feed addictive, the additive amount in feed is 0.2%.
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| CN201711112322.5A CN108371247A (en) | 2017-11-13 | 2017-11-13 | A kind of compound probiotic improving piglet survival rate |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711112322.5A CN108371247A (en) | 2017-11-13 | 2017-11-13 | A kind of compound probiotic improving piglet survival rate |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109329566A (en) * | 2018-12-05 | 2019-02-15 | 湖南赛福资源饲料科技有限公司 | For improving the premixed feed and preparation method of piglet gastrointestinal health |
| CN109362964A (en) * | 2018-09-18 | 2019-02-22 | 湖北省农业科学院畜牧兽医研究所 | A kind of zinc oxide substitute of prevention of diarrhea in piglets and preparation method thereof |
| CN110373369A (en) * | 2019-06-25 | 2019-10-25 | 华中农业大学 | A kind of recombined bacillus subtilis engineering bacteria, construction method and its application producing pig glutamine synthelase |
| CN114423442A (en) * | 2019-09-16 | 2022-04-29 | 诺维信公司 | Spore-based probiotic supplementation and control of endotoxemia in dogs |
-
2017
- 2017-11-13 CN CN201711112322.5A patent/CN108371247A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109362964A (en) * | 2018-09-18 | 2019-02-22 | 湖北省农业科学院畜牧兽医研究所 | A kind of zinc oxide substitute of prevention of diarrhea in piglets and preparation method thereof |
| CN109329566A (en) * | 2018-12-05 | 2019-02-15 | 湖南赛福资源饲料科技有限公司 | For improving the premixed feed and preparation method of piglet gastrointestinal health |
| CN110373369A (en) * | 2019-06-25 | 2019-10-25 | 华中农业大学 | A kind of recombined bacillus subtilis engineering bacteria, construction method and its application producing pig glutamine synthelase |
| CN114423442A (en) * | 2019-09-16 | 2022-04-29 | 诺维信公司 | Spore-based probiotic supplementation and control of endotoxemia in dogs |
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