CN108368155A - 人源性免疫抑制蛋白和肽作为药物的应用 - Google Patents

人源性免疫抑制蛋白和肽作为药物的应用 Download PDF

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Publication number
CN108368155A
CN108368155A CN201680070131.4A CN201680070131A CN108368155A CN 108368155 A CN108368155 A CN 108368155A CN 201680070131 A CN201680070131 A CN 201680070131A CN 108368155 A CN108368155 A CN 108368155A
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CN
China
Prior art keywords
amino acid
polypeptide
seq
protein
disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201680070131.4A
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English (en)
Chinese (zh)
Inventor
M·J·拉斯卡
A·M·特罗德伯格
K·斯特恩加德-彼得森
S·巴赫拉米
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elvin Co
Original Assignee
Elvin Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elvin Co filed Critical Elvin Co
Publication of CN108368155A publication Critical patent/CN108368155A/zh
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/10022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/10033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Transplantation (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN201680070131.4A 2015-10-01 2016-09-30 人源性免疫抑制蛋白和肽作为药物的应用 Pending CN108368155A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA201570620 2015-10-01
DKPA201570620 2015-10-01
DKPA201670634 2016-08-23
DKPA201670634 2016-08-23
PCT/DK2016/050316 WO2017054831A1 (en) 2015-10-01 2016-09-30 Use of human derived immunosuppressive proteins and peptides as medicaments

Publications (1)

Publication Number Publication Date
CN108368155A true CN108368155A (zh) 2018-08-03

Family

ID=57144698

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201680070131.4A Pending CN108368155A (zh) 2015-10-01 2016-09-30 人源性免疫抑制蛋白和肽作为药物的应用

Country Status (6)

Country Link
US (1) US20190040106A1 (https=)
EP (1) EP3356389A1 (https=)
JP (1) JP7037486B2 (https=)
CN (1) CN108368155A (https=)
CA (1) CA2999792A1 (https=)
WO (1) WO2017054831A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111630060A (zh) * 2017-09-01 2020-09-04 盈珀治疗有限公司 用于在疾病的预防和/或治疗中使用的疫苗

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3033262A1 (en) 2016-08-23 2018-03-01 Aimvion A/S Novel immunostimulating peptides
US11352421B2 (en) 2018-12-11 2022-06-07 Rush University Medical Center Treatment for adverse immune reaction to metal implant debris

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004087748A1 (en) * 2003-04-04 2004-10-14 Centre National De La Recherche Scientifique Protein with fusogenic activity, nucleic acid sequences encoding said protein and pharmaceutical compositions comprising the same
CN1961001A (zh) * 2004-03-30 2007-05-09 古斯达威罗斯研究所 参与病毒蛋白的免疫抑制作用的调节的多肽序列
WO2011119484A1 (en) * 2010-03-23 2011-09-29 Iogenetics, Llc Bioinformatic processes for determination of peptide binding

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020048763A1 (en) * 2000-02-04 2002-04-25 Penn Sharron Gaynor Human genome-derived single exon nucleic acid probes useful for gene expression analysis
EP2254592B1 (en) * 2008-02-28 2019-06-05 Dako Denmark A/S Mhc multimers in borrelia diagnostics and disease

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004087748A1 (en) * 2003-04-04 2004-10-14 Centre National De La Recherche Scientifique Protein with fusogenic activity, nucleic acid sequences encoding said protein and pharmaceutical compositions comprising the same
CN1961001A (zh) * 2004-03-30 2007-05-09 古斯达威罗斯研究所 参与病毒蛋白的免疫抑制作用的调节的多肽序列
WO2011119484A1 (en) * 2010-03-23 2011-09-29 Iogenetics, Llc Bioinformatic processes for determination of peptide binding

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NATHALIE DE PARSEVAL等: "Characterization of the Three HERV-H Proviruses with an Open Envelope Reading Frame Encompassing the Immunosuppressive Domain and Evolutionary History in Primates", 《VIROLOGY》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111630060A (zh) * 2017-09-01 2020-09-04 盈珀治疗有限公司 用于在疾病的预防和/或治疗中使用的疫苗
CN111630060B (zh) * 2017-09-01 2024-01-23 盈珀治疗有限公司 用于在疾病的预防和/或治疗中使用的疫苗

Also Published As

Publication number Publication date
WO2017054831A1 (en) 2017-04-06
US20190040106A1 (en) 2019-02-07
JP2018533974A (ja) 2018-11-22
CA2999792A1 (en) 2017-04-06
JP7037486B2 (ja) 2022-03-16
EP3356389A1 (en) 2018-08-08

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Application publication date: 20180803