CN108355025A - 一种治疗血栓性外痔的中药熏洗药剂及其制备方法 - Google Patents
一种治疗血栓性外痔的中药熏洗药剂及其制备方法 Download PDFInfo
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Abstract
本发明公开了一种治疗血栓性外痔的中药熏洗药剂及其制备方法,属中药领域。本发明药物有效成分的原料组成为:剪刀草、黄花母、丹参、地瓜藤、金樱根、韩信草、槐角、鹿角草、柏树叶、茜草、木通根、四季青、红楤木、竻慈姑、甘草、狼萁草、丹皮、槐白皮、刘寄奴、月季花、管仲、过江龙子、独一味、榼藤子。本发明选用药材的药性相适相辅,针对病因对症下药,有清热利湿、解毒消肿、破瘀通经、活血化瘀、行气止痛、收敛固涩、凉血止血、生肌敛疮之功效,吸收效果好,疗效显著,无毒副作用及临床不良反应,经临床验证对血栓性外痔治愈率较高。
Description
所属技术领域
本发明涉及中药领域,尤其涉及一种治疗血栓性外痔的中药熏洗药剂及其制备方法。
背景技术
血栓性外痔是临床多发病,常因过食辛辣刺激食物,大便临厕努挣,肛周皮下静脉破裂,血液淤积皮下而成。临床常以患者自觉肛门肿胀、疼痛有异物感为主症,检查可见肛周或肛管皮下有葡萄状暗紫色肿物,有时伴表面轻度糜烂出血。
目前西医治疗本病主要是手术治疗为主,但对于无条件者或年老体弱者及血栓不大者不能进行手术治疗,多采用西药内服及坐浴熏洗辅助进行治疗,治疗周期长,易复发,治疗效果不佳。
中医认为血栓性外痔是湿热下注魄门,脉络受损,气血瘀滞,血脉不通所致。故本发明中药根据病因对症下药,具有清热利湿、解毒消肿、破瘀通经、活血化瘀、行气止痛、收敛固涩、凉血止血、生肌敛疮之功效,吸收效果好,疗效显著,无毒副作用及临床不良反应,经临床验证对血栓性外痔治愈率较高。
发明内容
本发明提供了一种治疗血栓性外痔的中药熏洗药剂及其制备方法,具有清热利湿、解毒消肿、破瘀通经、活血化瘀、行气止痛、收敛固涩、凉血止血、生肌敛疮之功效,治病求源标本兼治,对各种原因引起的血栓性外痔均具有很好的疗效。
为实现上述目的,本发明的技术方案实施如下:
一种治疗血栓性外痔的中药熏洗药剂,制成所述药物有效成分的原料组成及重量份数为:
剪刀草20~30份、黄花母20~30份、丹参15~30份、地瓜藤15~30份、金樱根15~30份、韩信草15~25份、槐角15~25份、鹿角草15~25份、柏树叶10~20份、茜草10~20份、木通根10~20份、四季青9~15份、红楤木9~15份、竻慈姑9~15份、甘草9~15份、狼萁草9~15份、丹皮6~12份、槐白皮6~12份、刘寄奴6~12份、月季花3~9份、管仲3~9份、过江龙子2~6份、独一味1~4份、榼藤子1~4份。
制成所述药物有效成分的原料组成及重量份数为:
剪刀草22~28份、黄花母22~28份、丹参18~27份、地瓜藤18~26份、金樱根18~26份、韩信草18~22份、槐角18~22份、鹿角草18~22份、柏树叶12~18份、茜草12~18份、木通根12~16份、四季青11~13份、红楤木11~13份、竻慈姑11~13份、甘草11~13份、狼萁草11~13份、丹皮8~10份、槐白皮8~10份、刘寄奴8~10份、月季花5~8份、管仲5~8份、过江龙子3~5份、独一味2~4份、榼藤子1~3份。
制成所述药物有效成分的原料组成及重量份数为:
剪刀草25份、黄花母25份、丹参24份、地瓜藤24份、
金樱根22份、韩信草20份、槐角20份、鹿角草20份、
柏树叶15份、茜草15份、木通根14份、四季青12份、
红楤木12份、竻慈姑12份、甘草12份、狼萁草12份、
丹皮9份、槐白皮9份、刘寄奴9份、月季花7份、
管仲6份、过江龙子4份、独一味3份、榼藤子2份。
一种治疗血栓性外痔的中药熏洗药剂的制备方法,包括以下工艺步骤:
(1)将剪刀草、黄花母、地瓜藤、金樱根、鹿角草、柏树叶、四季青、竻慈姑、狼萁草、丹皮、槐白皮、刘寄奴、月季花、过江龙子、榼藤子洗净后放入容器中,加入8-10倍量的蒸馏水浸泡4-5小时,加热煮沸3-4小时,提取浸液;再次加入6-8倍量的蒸馏水,加热煮沸2-3小时,提取浸液;最后再加入4-6倍量的蒸馏水,加热煮沸1-2小时,提取浸液;合并三次浸液,过滤,得滤液备用;
(2)取丹参片,加黄酒拌匀,闷润至透,置锅内,用文火炒,取出放凉,粉碎研末,过140目细筛,得细粉,备用;
(3)将韩信草、木通根、红楤木、管仲、独一味洗净放入容器内,加入4倍量的浓度80%的乙醇溶液,浸泡1-2小时,加热回流提取3-4小时,过滤,得滤液备用;
(4)取槐角置锅内用文火炒至鼓起,喷入蜜水,再炒至外皮光亮、不粘手为度,取出放凉,粉碎研末,过140目细筛,得细粉,备用;
(5)取净茜草片与黄酒拌匀,置锅内用文火微炒,取出,晾干,粉碎研末,过140目细筛,得细粉,备用;
(6)取净甘草片,加入炼熟的蜂蜜与少许开水,拌匀后稍闷,置炒制容器内,文火炒至深黄色,不粘手时取出,放凉,粉碎研末,过140目细筛,得细粉,备用;
(7)将上述步骤(1)~(6)所制得的滤液以及细粉混合后,加入8~10倍量的蒸馏水,搅拌溶解均匀后,加热煮沸0.5小时,至60℃以下,静置1小时,过滤,得滤液,将滤液灌装150ml药液袋包装封存,即得所述的中药熏洗药剂。
本发明所用中药的药性如下:
剪刀草:味苦;辛;性凉。祛风清热;行气活血;解毒消肿。主治感冒发热;食积腹痛;呕吐;泄泻;痢疾;白喉;咽喉肿痛;痈肿丹毒;荨麻疹;毒虫咬伤;跌打伤出血。《湖南药物志》:行气,散血,消积。
黄花母:味甘;辛;性凉。归心;肝;肺;大肠;小肠经。清热利湿;解毒消肿。主治感冒高热;咽喉肿痛;湿热泻痢;黄疸;带下;淋证;风湿痿弱;头晕;劳卷乏力;痔血;痈疽疔疮。《泉州本草》:清热散瘀,凉血止血,治肠痔痼疾,下血。
丹参:味苦;性微寒;无毒。入心;肝经。活血祛瘀,通经止痛,清心除烦,凉血消痈。用于胸痹心痛,脘腹胁痛,瘕瘕积聚,热痹疼痛,心烦不眠,月经不调,痛经经闭,疮疡肿痛。《本经》载:“主心腹邪气,肠鸣幽幽如走水,寒热积聚;破症除瘕,止烦满,益气。”现代医学研究证实,丹参具有消炎止痛、扩张冠状动脉、改善心肌缺血状况、降血压、降血糖、降血脂、保肝、抗菌和促进组织的修复与再生的作用,丹参还具有抗血小板凝聚、降低血液黏度及调节内外凝血系统的功能。
地瓜藤:味苦;性寒。清热利湿,活血通络,解毒消肿。主治肺热咳嗽;痢疾;水肿;黄疽;小儿消化不良;风湿疼痛;经闭;带下;跌打损伤;痔疮出血;无名肿毒。《四川中药志》:利小便,消湿热黄肿,通月闭,止白带;治痔疮出血及牙龈肿痛。
金樱根:味酸涩;甘;性平;无毒。归肾;大肠经。收敛固涩,止血敛疮,祛内活血,止痛,杀虫。主治滑精;遗尿;痢疾;泄泻;咳血;便血;崩漏;带下;脱肛;子宫下垂;风湿痹痛;跌打损伤;疮疡;烫伤;牙痛;胃痛;蛔虫症;诸骨哽喉;乳糜尿。《生草药性备要》:旺血,理痰火,洗疳疔,痔疮。
韩信草:味辛;苦;性寒。归心;肝;肺经。清热解毒;活血止痛;止血消肿。主治痈肿疔毒;肺痈;肠痈;瘰疬;毒蛇咬伤;肺热咳喘;牙痛;喉痹;咽痛;筋骨疼痛;吐血;咯血;便血;跌打损伤;创伤出血;皮肤瘙痒。《泉州本草》:清热解毒,消肿退癀,逐血破瘀,排脓消痈,凉血止血,利咽喉。主治一切喉癀,亦治肺火高热喘咳,吐血,咳血咯血,疯血作痛,刀伤出血,恶疮痈肿,虎、犬咬伤。
槐角:味苦;性寒。凉血止血;清肝明目。主治痔疮出血;肠风下血;血痢;崩漏;血淋;血热吐衄;肝热目赤;头晕目眩。《滇南本草》:"止血散疽。""治五痔肠风下血,赤白热泻痢疾。"现代医学研究证明:槐角中含大量芦丁,芦丁具有抗炎作用,具有维持血管抵抗力,降低其通透性,减少脆性等作用,还有抗病毒和抑制醛糖还原酶的作用。
鹿角草:味微苦;微辛;性凉。清热利湿;解毒消肿;活血止血。主治痢疾;泄泻浮肿;咳嗽;哮喘;扁桃体炎;咳血;尿血;痈疖肿毒;带状疱疹;跌打肿痛;外伤出血。《泉州本草》:清热解毒,去瘀活血,通调水道。治痈疽疖肿,小便赤涩。
柏树叶:味苦;涩;性平。凉血止血;敛疮生肌。主治吐血;血痢;痔疮;癞疮;烫伤;刀伤;毒蛇咬伤。《分类草药性》:和血。治肠风痔肿,痢疾,吐血;兼涂小儿肥疮。
茜草:味苦;性寒。归肝;心;肾;脾;胃;心包经。凉血止血;活血化瘀;主治血热咯血;吐血;衄血;尿血;便血;崩漏;经闭;产后瘀阻腹痛;跌打损伤;风湿痹痛;黄疸;疮痈;痔肿。《本草经疏》载:“止鼻洪,带下,产后血晕,乳结,月经不止,肠风痔瘘,排脓,治疮疖,泄精,尿血,扑损瘀血,皆取其凉血行轿,苦寒泄热之功耳。”现代医学研究证实,茜草对金黄色葡萄球菌、白色葡萄球菌、溶血性链球菌、肺炎双球菌、卡他球菌、流感杆菌有一定的抑制作用,对人型结核杆菌有抑制作用,有降低血压却不影响心脏的功效,纠正肝素引起的凝血障碍,有利尿及兴奋离体肠管的作用。
木通根:味苦;性平;归肝;肾经。祛风通络;利水消肿;行气活血;补肝肾;强筋骨。主治风湿痹痛;跌打损伤;经闭;疝气;睾丸肿痛;脘腹胀闷;小便不利;带下;虫蛇咬伤。《浙江民间常用草药》:祛风止痛,行气活血,利尿解毒。
四季青:味苦;涩;性凉。清热解毒;生肌敛疮;活血止血。主治肺热咳嗽;咽喉肿痛;痢疾;腹泻;胆道感染;尿路感染;冠心病心绞痛;烧烫伤;热毒痈肿;下肢溃疡;麻风溃疡;湿疹;冻疮;皲裂;血栓闭塞性脉管炎;外伤出血。《本草拾遗》载:“微酸性热,主生肌,敛疮,活血,止血。”现代医学研究证实,四季青有广谱抗菌作用,对绿脓杆菌、大肠杆菌、伤寒杆菌、福氏痢疾杆菌、产碱杆菌、枯草杆菌、金黄色葡萄球菌均有抑制作用,能促进创面消肿,形成保护性痂膜,降低心肌耗氧量,扩张冠脉,所含的儿茶酸有显著的抗炎作用,此外还有抑制肿瘤的功效。
红楤木:味微苦;辛;性平。祛风除湿;活血行气;解毒消肿。主治风湿痹痛;跌打肿痛;骨折;胃脘胀痛;疝气;崩漏;骨髓炎;痈疽;蛇咬伤。《常用中草药单方验方选编》:活血破瘀,祛风行气,清热解毒。治跌打损伤,骨折,妇女败血,骨髓炎,痈疽,狂犬咬伤,风湿痹痛。
竻慈姑:味苦;辛;性凉。归心;肺;膀胱经。清热利湿;解毒消肿;健胃消食。主治热病口渴;风热咳嗽;小便黄赤;肾炎水肿;白带;风湿痹痛;跌打肿痛;慢性胃炎;消化不良;小儿头疮;胎毒;痄腮;淋巴结结核;痈肿疮疖;毒蛇咬伤。
甘草:味甘;性平。归心;肺;脾;胃经。补脾益气;清热解毒;祛痰止咳;缓急止痛;调和诸药。主治脾胃虚弱;倦怠乏力;心悸气短;咳嗽痰多;脘腹四肢挛急疼痛;痈肿疮毒;缓解药物毒性。《本草纲目》载:“诸药中甘草为君。治七十二种乳石毒,解一千二百般草本毒,调和从药有功。”现代医学研究证实,甘草有较强的解毒作用,还有抗溃疡、抗炎症、镇痉镇咳、降血压、降血脂、抗癌作用,广泛用于治疗咽喉炎、喉炎、气管炎、支气管炎、哮喘、咳嗽、咳血等疾病,此外还具有抗胃溃疡、抗胃炎作用。
狼萁草:味苦;甘;性平。止血;接骨;清热利湿;解毒消肿。主治血崩;鼻衄;咳血;外伤出血;跌打骨折;热淋涩痛;白带;风疹瘙痒;疮肿;烫伤;痔瘘;蛇虫咬伤;咳嗽。
丹皮:味辛;苦;性凉;微寒。入心;肝;肾;肺经。清热;活血化瘀。主治温热病热入血分;发斑;吐衄;热泪盈眶;病毒后期热伏阴分发热;阴虚骨蒸潮热;血滞经闭;痛经;痈肿疮毒;跌扑伤痛;风湿热痹。《神农本草经》载:“主寒热,中风瘛疭、痉、惊痫邪气,除症坚瘀血留舍肠胃,安五脏,疗痈疮。现代医学研究证实,丹皮有解热、抗炎、抗变态反应等作用,有效增强体液及细胞的免疫功能,对心肌缺血有明显保护作用,对血小板聚集有明显的抑制作用。
槐白皮:味苦;性平。归肺;心;肝;大肠经。祛风除湿;敛疮生肌;消肿解毒。主治风邪外中;身体强直;肌肤不仁;热病口疮;牙疳;喉痹;肠风下血;疽;痔疮;痈疽疮疡;阴部湿疮;水火烫伤。《别录》:主烂疮。
刘寄奴:味辛;微苦;性温。归心;肝;脾经。破瘀通经;止血消肿;消食化积。主治经闭;痛经;产后瘀滞腹痛;恶露不尽,癥瘕;跌打损伤;金疮出血;风湿痹痛;便血;尿血;痈疮肿毒;烫伤;食积腹痛;泄泻痢疾。《开宝本草》:疗金疮,止血为要药;产后余疾,下血、止痛。现代医学研究证明;刘寄奴能解除平滑肌痉挛、加速血液循环和促进凝血。
月季花:味甘;性温;无毒。归肝;肾经。活血调经;解毒消肿。主治月经不调;痛经;闭经;跌打损伤;瘀血肿痛;瘰疬;痈肿;烫伤。《泉州本草》:通经活血化瘀,清肠胃湿热,泻肺火,止咳,止血止痛,消痈毒。治肺虚咳嗽咯血,痢疾,瘰疬溃烂,痈疽肿毒,妇女月经不调。
管仲:味苦涩;性寒。归脾;大肠经。清热解毒,涩肠止泻,凉血止血。主治赤白下痢;肠炎腹泻;肠风下血;肺痨咯血;吐血;崩漏带下;外伤出血;疔疮;烫烧伤。《云南思茅中草药选》:清热止血,消炎收敛。治痢疾,肠炎,胃痛,咯血,吐血,外伤出血,痛经。
过江龙子:味苦辛;性温。归肝;胃经。行气止痛;活血化瘀。主治胁肋胀痛,胃脘痛,跌打损伤。《岭南采药录》:止气痛,理跌打伤、去瘀生新。
独一味:味甘;苦;性平。活血化瘀;消肿止痛。主治跌打损伤;筋骨疼痛;关节肿痛;痛经;崩漏。《四川中药志》:活血行瘀,止痛,行气,消肿,续筋接骨。治跌伤筋骨及闪腰挫气等症。现代医学研究证明:独一味对免疫功能具有一定的作用,并具有镇痛、抗菌、止血的作用。
榼藤子:味涩甘;性平;无毒。归胃;肝;大肠经。行气止痛,利湿消肿。主治脘腹胀痛,黄疸,脚气水肿,痢疾,痔疮,脱肛,喉痹。《本草拾遗》:主五痔,喉痹,以仁为粉,微熬,水服一、二匕。
本发明与现有技术相比,具有以下有益效果:
本发明选用药材的药性相适相辅,针对病因对症下药,有清热利湿、解毒消肿、破瘀通经、活血化瘀、行气止痛、收敛固涩、凉血止血、生肌敛疮之功效,吸收效果好,疗效显著,无毒副作用及临床不良反应,经临床验证对血栓性外痔治愈率较高。
具体实施方式
下面结合具体实施例对本发明做进一步阐述。
实施例1
本发明药物有效成分的原料组成及重量为:
剪刀草20~30份、黄花母20~30份、丹参15~30份、地瓜藤15~30份、金樱根15~30份、韩信草15~25份、槐角15~25份、鹿角草15~25份、柏树叶10~20份、茜草10~20份、木通根10~20份、四季青9~15份、红楤木9~15份、竻慈姑9~15份、甘草9~15份、狼萁草9~15份、丹皮6~12份、槐白皮6~12份、刘寄奴6~12份、月季花3~9份、管仲3~9份、过江龙子2~6份、独一味1~4份、榼藤子1~4份。
本发明药物制备方法的工艺步骤为:
(1)将剪刀草、黄花母、地瓜藤、金樱根、鹿角草、柏树叶、四季青、竻慈姑、狼萁草、丹皮、槐白皮、刘寄奴、月季花、过江龙子、榼藤子洗净后放入容器中,加入8-10倍量的蒸馏水浸泡4-5小时,加热煮沸3-4小时,提取浸液;再次加入6-8倍量的蒸馏水,加热煮沸2-3小时,提取浸液;最后再加入4-6倍量的蒸馏水,加热煮沸1-2小时,提取浸液;合并三次浸液,过滤,得滤液备用;
(2)取丹参片,加黄酒拌匀,闷润至透,置锅内,用文火炒,取出放凉,粉碎研末,过140目细筛,得细粉,备用;
(3)将韩信草、木通根、红楤木、管仲、独一味洗净放入容器内,加入4倍量的浓度80%的乙醇溶液,浸泡1-2小时,加热回流提取3-4小时,过滤,得滤液备用;
(4)取槐角置锅内用文火炒至鼓起,喷入蜜水,再炒至外皮光亮、不粘手为度,取出放凉,粉碎研末,过140目细筛,得细粉,备用;
(5)取净茜草片与黄酒拌匀,置锅内用文火微炒,取出,晾干,粉碎研末,过140目细筛,得细粉,备用;
(6)取净甘草片,加入炼熟的蜂蜜与少许开水,拌匀后稍闷,置炒制容器内,文火炒至深黄色,不粘手时取出,放凉,粉碎研末,过140目细筛,得细粉,备用;
(7)将上述步骤(1)~(6)所制得的滤液以及细粉混合后,加入8~10倍量的蒸馏水,搅拌溶解均匀后,加热煮沸0.5小时,至60℃以下,静置1小时,过滤,得滤液,将滤液灌装150ml药液袋包装封存,即得所述的中药熏洗药剂。
用法用量:将1袋本发明中药熏洗药剂倒入熏洗容器中,加适量水后搅拌均匀,加热至沸腾,先以药气熏蒸患处,待水温降至50℃左右时,坐入熏洗盆内,将外痔浸入药液中浸泡,若水温下降可加温后再泡,每次熏洗时间不少于30分钟,每日2次,7天为1疗程。
实施例2
本发明药物有效成分的原料组成及重量为:
剪刀草22~28份、黄花母22~28份、丹参18~27份、地瓜藤18~26份、金樱根18~26份、韩信草18~22份、槐角18~22份、鹿角草18~22份、柏树叶12~18份、茜草12~18份、木通根12~16份、四季青11~13份、红楤木11~13份、竻慈姑11~13份、甘草11~13份、狼萁草11~13份、丹皮8~10份、槐白皮8~10份、刘寄奴8~10份、月季花5~8份、管仲5~8份、过江龙子3~5份、独一味2~4份、榼藤子1~3份。
本实施例的药物制备方法工艺步骤及用法用量与实施例1相同。
实施例3
本发明药物有效成分的原料组成及重量为:
剪刀草25份、黄花母25份、丹参24份、地瓜藤24份、
金樱根22份、韩信草20份、槐角20份、鹿角草20份、
柏树叶15份、茜草15份、木通根14份、四季青12份、
红楤木12份、竻慈姑12份、甘草12份、狼萁草12份、
丹皮9份、槐白皮9份、刘寄奴9份、月季花7份、
管仲6份、过江龙子4份、独一味3份、榼藤子2份。
本实施例的药物制备方法工艺步骤及用法用量与实施例1相同。
临床资料:
1、病例选择
选择我院确诊的血栓性外痔患者80例临床观察,病人随机分成两组。治疗组40例,其中男性27例,女性13例,年龄19~64岁,平均年龄43.6岁,病程最短者11天,最长者36天,平均21.8天。对照组40例,其中男性28例,女性12例,年龄17~63岁,平均年龄44.1岁,病程最短者14天,最长者38天,平均22.4天。两组资历基本一致,无显著差异,具有可比性。
2、治疗方法
治疗组患者使用本发明中药熏洗药剂,将1袋本发明中药熏洗药剂倒入熏洗容器中,加适量水后搅拌均匀,加热至沸腾,先以药气熏蒸患处,待水温降至50℃左右时,坐入熏洗盆内,将外痔浸入药液中浸泡,若水温下降可加温后再泡,每次熏洗时间不少于30分钟,每日2次,7天为1疗程,治疗3个疗程。
对照组患者采用硫酸镁配合高锰酸钾粉化水坐浴,每日熏洗坐浴2次,治疗21天。
3、疗效判定:
(1)痊愈:临床症状全部消失,肿块消失,疼痛等不适感完全消失。
(2)好转:临床症状明显缓解,肿块明显缩小。
(3)无效:症状同施治前无明显差异。
4、结果
治疗组中治愈31例,好转5例,无效4例,治愈率77.5%,总有效率90%。
对照组中治愈24例,好转6例,无效10例,治愈率60%,总有效率75%。
以上结果显示,治疗组的治愈率和总有效率明显高于对照组。
典型病例举例:
1、赵××,男,45岁。该患者肛门时有疼痛,肛缘处有紫色肿块,情况愈发严重。后来来院问诊,诊断为血栓性外痔,经使用本发明中药熏洗药剂3个疗程后,上述症状完全消失,已痊愈。
2、何××,男,58岁。该患者疼痛剧烈,肛门处有硬而滑的淤血块,有便血。后来来院问诊,诊断为血栓性外痔,经使用本发明中药熏洗药剂3个疗程后,上述症状完全消失,已痊愈。
血栓性外痔是临床多发病,常因过食辛辣刺激食物,大便临厕努挣,肛周皮下静脉破裂,血液淤积皮下而成。本发明中药熏洗药剂根据病因对症下药,方中黄花母、狼萁草、竻慈姑、鹿角草、地瓜藤可清热利湿、活血通络、解毒消肿;方中木通根、剪刀草、红楤木可祛风通络、行气活血;方中刘寄奴、韩信草可破瘀通经、止血消肿;方中丹参、丹皮、茜草、独一味、月季花可活血化瘀;方中金樱根可收敛固涩、止血敛疮;方中四季青、槐白皮、柏树叶、管仲、槐角可清热解毒、凉血止血、敛疮生肌;方中榼藤子、过江龙子可行气止痛;方中甘草可调和诸药;方中诸药合用可共奏清热利湿、解毒消肿、破瘀通经、活血化瘀、行气止痛、收敛固涩、凉血止血、生肌敛疮之功效,通过中药外用熏洗,可改善局部血液循环,疏通瘀滞使淤血去,水肿消,疼痛止,杀菌消炎,促进创面组织快速修复,吸收效果好,疗效显著,无毒副作用及临床不良反应,经临床验证对血栓性外痔治愈率较高。
Claims (4)
1.一种治疗血栓性外痔的中药熏洗药剂,其特征在于:制成所述药物有效成分的原料组成及重量份数为:
剪刀草20~30份、黄花母20~30份、丹参15~30份、地瓜藤15~30份、
金樱根15~30份、韩信草15~25份、槐角15~25份、鹿角草15~25份、
柏树叶10~20份、茜草10~20份、木通根10~20份、四季青9~15份、
红楤木9~15份、竻慈姑9~15份、甘草9~15份、狼萁草9~15份、
丹皮6~12份、槐白皮6~12份、刘寄奴6~12份、月季花3~9份、
管仲3~9份、过江龙子2~6份、独一味1~4份、榼藤子1~4份。
2.根据权利要求1所述的一种治疗血栓性外痔的中药熏洗药剂,其特征在于:制成所述药物有效成分的原料组成及重量份数为:
剪刀草22~28份、黄花母22~28份、丹参18~27份、地瓜藤18~26份、
金樱根18~26份、韩信草18~22份、槐角18~22份、鹿角草18~22份、
柏树叶12~18份、茜草12~18份、木通根12~16份、四季青11~13份、
红楤木11~13份、竻慈姑11~13份、甘草11~13份、狼萁草11~13份、
丹皮8~10份、槐白皮8~10份、刘寄奴8~10份、月季花5~8份、
管仲5~8份、过江龙子3~5份、独一味2~4份、榼藤子1~3份。
3.根据权利要求1所述的一种治疗血栓性外痔的中药熏洗药剂,其特征在于:制成所述药物有效成分的原料组成及重量份数为:
剪刀草25份、黄花母25份、丹参24份、地瓜藤24份、
金樱根22份、韩信草20份、槐角20份、鹿角草20份、
柏树叶15份、茜草15份、木通根14份、四季青12份、
红楤木12份、竻慈姑12份、甘草12份、狼萁草12份、
丹皮9份、槐白皮9份、刘寄奴9份、月季花7份、
管仲6份、过江龙子4份、独一味3份、榼藤子2份。
4.一种治疗血栓性外痔的中药熏洗药剂的制备方法,其特征在于:包括以下工艺步骤:
(1)将剪刀草、黄花母、地瓜藤、金樱根、鹿角草、柏树叶、四季青、竻慈姑、狼萁草、丹皮、槐白皮、刘寄奴、月季花、过江龙子、榼藤子洗净后放入容器中,加入8-10倍量的蒸馏水浸泡4-5小时,加热煮沸3-4小时,提取浸液;再次加入6-8倍量的蒸馏水,加热煮沸2-3小时,提取浸液;最后再加入4-6倍量的蒸馏水,加热煮沸1-2小时,提取浸液;合并三次浸液,过滤,得滤液备用;
(2)取丹参片,加黄酒拌匀,闷润至透,置锅内,用文火炒,取出放凉,粉碎研末,过140目细筛,得细粉,备用;
(3)将韩信草、木通根、红楤木、管仲、独一味洗净放入容器内,加入4倍量的浓度80%的乙醇溶液,浸泡1-2小时,加热回流提取3-4小时,过滤,得滤液备用;
(4)取槐角置锅内用文火炒至鼓起,喷入蜜水,再炒至外皮光亮、不粘手为度,取出放凉,粉碎研末,过140目细筛,得细粉,备用;
(5)取净茜草片与黄酒拌匀,置锅内用文火微炒,取出,晾干,粉碎研末,过140目细筛,得细粉,备用;
(6)取净甘草片,加入炼熟的蜂蜜与少许开水,拌匀后稍闷,置炒制容器内,文火炒至深黄色,不粘手时取出,放凉,粉碎研末,过140目细筛,得细粉,备用;
(7)将上述步骤(1)~(6)所制得的滤液以及细粉混合后,加入8~10倍量的蒸馏水,搅拌溶解均匀后,加热煮沸0.5小时,至60℃以下,静置1小时,过滤,得滤液,将滤液灌装150ml药液袋包装封存,即得所述的中药熏洗药剂。
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