CN108310254A - A kind of preparation method of cardiovascular health natural plant composition - Google Patents
A kind of preparation method of cardiovascular health natural plant composition Download PDFInfo
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Abstract
The invention discloses a kind of preparation methods of cardiovascular health natural plant composition, and the specific process includes the following steps:(1) piemarker produces liquid;(2) hawthorn extract;(3) medicine parsley extracting solution;(4) Radix Salviae Miltiorrhizae leaf extract;(5) Radix Astragali extractive solution;(6) glutinous rice liquor is made by oneself;(7) piemarker prepared by above-mentioned steps is produced into 23 parts by weight of liquid, 13 parts by weight of hawthorn extract, 12 parts by weight of medicine parsley extracting solution, 47 parts by weight of Radix Salviae Miltiorrhizae leaf extract, 1.5 4 parts by weight of Radix Astragali extractive solution and self-control 8 15 parts by weight of glutinous rice liquor, it is put into agitator tank and is mixed 10 15 minutes, then 24 36 hours are stood in 05 DEG C of environment, powder processed after spray drying, using ultraviolet disinfection 15 minutes, powdered cardiovascular health natural plant composition is obtained.Product is directly prepared from natural materials, and without any additive, instant-drink is mellow, is a kind of health drink.
Description
Technical field:
The invention belongs to health care beverage products preparing technical fields, and in particular to a kind of cardiovascular health is combined with natural plants
The preparation method of object, by the way that piemarker is produced liquid, hawthorn extract, medicine parsley extracting solution, Radix Salviae Miltiorrhizae leaf extract, Radix Astragali extractive solution
It is mixed with self-control glutinous rice liquor, is prepared for a kind of speed with multi-efficiencies such as promoting blood circulation and removing blood stasis, clearing and activating the channels and collaterals, detumescence ding-tongs
Molten electuary natural drug composition can expand coronary artery, improve coronary blood supply amount and oxygen-supplying amount, solve asking for myocardial ischemia
Topic.
Background technology:
Coronary atherosclerotic heart disease, also known as coronary heart disease are that Atheromatosis occurs for coronary artery
Become and cause lumen of vessels stenosis or occlusion, caused by causing myocardial ischemia-anoxemia (angina pectoris) or myocardial necrosis (myocardial infarction)
Heart disease.Symptoms are that a kind of squeezing property pain occurs for thoracic cavity center, and can delay to neck, arm, back and stomach, simultaneously
May with dizziness, shortness of breath, perspire, shiver, nausea and fainting, severe patient can lead to death.The World Health Organization is to coronary heart disease
Classified as follows:(1) silent myocardial ischemia;(2) angina pectoris;(3) myocardial infarction;(4) ischemic cardiomyopathy;(5) sudden
Extremely.Silent myocardial ischemia type:It is called silent myocardial ischemia or invisible myocardial ischemia, refers to and truly has the objective of myocardial ischemia
Evidence (electrocardio-activity, left chamber function, Myocardial Perfusion and myocardial metabolism etc. abnormal), but lack pectoralgia or with myocardial ischemia phase
The subjective symptom of pass.Angina pectoris:Refer to by coronary insufficiency, cardiac muscle drastically, caused by ischemia and anoxic
It is the one group of clinical syndrome mainly showed with ictal pectoralgia or chest discomfort.Myocardial infarction/dead type:Refer to that coronary artery goes out
Existing atherosclerotic plaque or on this basis thrombosis, cause blood flow coronarius drastically to reduce or interrupt, and make corresponding
There is serious and enduringly acute ischemia in cardiac muscle, eventually leads to the ischemic necrosis of cardiac muscle, belongs to the serious types of coronary heart disease.Ischemic
Property cardiomyopathy type:Refer to since long-term myocardial ischemia leads to myocardium limitation or diffuse fibrousization, to generate heart contraction
And/or diastolic function is impaired, causes a series of clinical manifestations such as Heart enlargement or stiff, congestive heart failure, arrhythmia cordis
Clinical syndrome.Sudden death type:It is now recognized that patient's heart arrest is on the basis of coronary atherosclerosis
On, coronarospasm or microcirculation embolism, which occurs, leads to Acute myocardial ischemia, causes local electro physiology disorderly, causes temporary
Caused by severe arrhythmia (especially ventricular fibrillation).As the improvement of people's living standards, bad life habits, and do not conform to
Diet is managed, causes high blood pressure, dyslipidemia, overweight/obesity, blood glucose height etc., and then lead to coronary heart disease, coronary heart disease has become
It is only second to the second largest disease for endangering human health of cancer, morbidity crowd is mainly the elderly, and morbidity crowd's gradual year
Lightization.Currently, the drug for the treatment of coronary heart disease mainly has:Quinindium, procainamide, lidocaine, Propafenone, Mei Tuoluo
That, amiodarone etc., although therapeutic effect is good, effect is rapid, and there are palliative, long-term use is susceptible to malicious secondary make
With, such as palpitaition, dizziness, insomnia etc., while the defect of damage is caused to cardiac muscle.Compared with Western medicine, the toxic side effect of Chinese medicine is small,
It starts with from whole conditioning, in the advantage that improvement clinical symptoms etc. have Western medicine irreplaceable, is expected to become western in the market
The important substitute products of medicine.Coronary heart disease is that qi deficiency to blood stasis, the heart arteries and veins stasis of blood are stifled in the pathologic basis of Chinese medicine.Therefore, existing Chinese medicine
Therapy is usually to achieve the purpose that treat coronary heart disease in terms of promoting blood circulation, the scattered stasis of blood, promoting menstruation, tonifying Qi, analgesic are several.Patent
CN104906524B discloses a kind of Chinese medicine package and its instructions of taking, production method for treating coronary heart disease, is wrapped in Chinese medicine package
Radix Salviae Miltiorrhizae, safflower, corydalis tuber, Rhizoma Chuanxiong, turmeric, ginseng, the Chinese bulbul, Radix Ophiopogonis and uncaria are included, which expands with good coronary artery
Zhang Xiaoguo improves coronary blood supply amount and oxygen-supplying amount, solves the problems, such as myocardial ischemia, to protect cardiac muscle, delay by expanding coronary artery
Solve the symptoms such as angina pectoris.Patent CN105147923B discloses a kind of Chinese medicine composition and preparation method thereof for treating coronary heart disease,
It works out treatment coronary heart disease optimum proportioning by adjusting the ratio of dragon's blood, wind face cream and Radix Salviae Miltiorrhizae, will be effective in various medicinal materials
Ingredient fully extracts, and plays maximum drug effect.CN104398867B discloses a kind of drug for treating arrhythmia cordis coronary heart disease
Composition comprising longan seed, glutinous rice root, cordate houttuynia, dry land grass, bicolor, carbonized hair, cortex acanthopanacis, Flos Magnoliae Officinalis, root of gansui part,
Tangerine leaf and paniculate swallowwort, the experimental results showed that:The Chinese medicine composition is held in the palm for treating arrhythmia cordis coronary heart disease effect better than Western medicine U.S.
Luo Er.Patent CN102068491B discloses a kind of pharmaceutical composition for treating coronary heart diseases and angina pectoris comprising leech, Radix Astragali,
Radix Salviae Miltiorrhizae, Radix Notoginseng and dalbergia wood, with better pharmacological action compared with marketed drugs.Dietotherapy is a kind of important treatment hand in Chinese medicine
Section is not only able to organ and tissue " supporting ", and can be with strong physique by edible natural substance by body.For example, specially
Sharp CN102077940B discloses a kind of dedicated sea dietary of patients with coronary heart disease, is main with food-borne marine oligopeptide
Raw material adds marine bioactivity polysaccharide, then is aided with seawood meal, nutrient amino acids, oligosaccharide, nutrient, vitamin and mineral
Matter is mixed with;Patent CN101485775B discloses a kind of pilose antler and allicin wine for treating coronary heart disease, by five kinds of Chinese medicine deer
Young pilose antler, Radix Rehmanniae, Cortex Eucommiae, hawthorn and pueraria lobata are made with honey, garlic, rice vinegar, white spirit mixed, and clinical effectiveness shows it to coronary heart disease
With fine curative effect.Based on this, the present invention selects the food of integration of drinking and medicinal herbs, studies a kind of cardiovascular health with using natural plants
Composition and preparation method thereof.
Invention content:
It is a kind of with the multi-efficiencies such as promoting blood circulation and removing blood stasis, clearing and activating the channels and collaterals, detumescence ding-tong it is an object of the invention to be prepared for
Instant formula natural drug composition and preparation method thereof, the instant natural drug composition can expand coronary artery,
Improve coronary blood supply amount and oxygen-supplying amount, solves the problems, such as myocardial ischemia and cardiovascular health.
To achieve the goals above, the preparation method of cardiovascular health natural plant composition of the present invention, tool
Body technology process includes the following steps:
(1) piemarker produces liquid:The band shell piemarker seed for picking season in midsummer, then separates piemarker seed shell and piemarker seed,
Pulled out immediately after piemarker seed shell first being put in the water of boiling leaching drift 3-5 minute in the cold water for be put into 5-10 DEG C cross wash cool down after smash
It is broken;It is ground into powdery after piemarker seed is fried again, is then added in 5 times of water, decocts 2-3 hours, cool in nonmetal pot
After obtain pulpous state piemarker seed decoct slurries;The piemarker seed shell smashed to pieces and piemarker seed are decocted into 200 mesh pressures after slurries mix again
Filter, filtrate is placed in conical flask with stopper, and the weight percent concentration that 5 times of amounts are added is 75% ethanol water, is shaken in ultrasound
Concussion extraction 1 hour, supersonic frequency 80-100KHZ in device is swung, then ethyl alcohol is recycled with Rotary Evaporators, obtains a concentration of
It is spare that the piemarker of 2g/ml produces liquid;
(2) hawthorn extract:After the hawthorn picked is screened, cleans, smashs to pieces after frost is beaten, the 6-8 times of water measured of addition
In stir evenly, heating water bath, refluxing extraction 3-5 times at 60-70 DEG C is 1-2 hours each, will each time extracting solution merge
200 mesh filter, and filtrate is concentrated into a concentration of 10g/L, obtains hawthorn extract, is added into hawthorn extract powder activated
Charcoal, in pH=3.0, under the conditions of temperature is 60 DEG C, ultrasonic vibration decoloration 30-40min obtains a concentration of 5g/L hawthorn extracts;
(3) medicine parsley extracting solution:Picking fresh drug parsley is smashed to pieces after impregnating 18-24 hours in 48-50 DEG C of warm water, so
The weight percent concentration that 7 times of amounts are added afterwards is to be stirred evenly in 75% ethanol water, heating water bath, in 55-75 DEG C of temperature
Degree lower refluxing extraction 3-5 time will be concentrated under reduced pressure, recycling ethyl alcohol obtains a concentration of after extracting solution merges the filtering of 200 mesh each time
3g/L medicine parsley extracting solutions;
(4) Radix Salviae Miltiorrhizae leaf extract:It after Radix Salviae Miltiorrhizae leaf is dried, crushes, crosses 200 mesh sieve, be placed in conical flask with stopper, be added 3
The weight percent concentration of amount is 75% ethanol water again, then concussion extraction 2-4h, supersonic frequency in ultrasonator
For 90-120KHz, 200 mesh filter to take filtrate, and ethyl alcohol is recycled with Rotary Evaporators, under conditions of 3500rpm, centrifuge 15min,
Supernatant is taken, a concentration of 4g/L, as Radix Salviae Miltiorrhizae leaf extract are concentrated under reduced pressure into;
(5) Radix Astragali extractive solution:Radix Astragali is smashed to pieces, 3 times of amount water decoctions are then added and take decocting liquid within 2 hours, then add 2 times
Water, which decocts, takes decocting liquid for 1.5 hours, merges decocting liquid twice, is concentrated under reduced pressure under conditions of 0.05Mpa, 60 DEG C, weight is then added
Percent concentration is that 95% ethyl alcohol shakes extraction 2-4h in ultrasonator, obtains the Radix Astragali extractive solution of a concentration of 4g/L;
(6) glutinous rice liquor is made by oneself:Glutinous rice clear water is eluriated 3-4 times, is then impregnated 2-3 hours at 5-15 DEG C, then with clearly
Water washing 3-5 times, cooks glutinous rice after draining away the water, and sterile water and distiller's yeast, at 30-38 DEG C, ferment at constant temperature are added after cooling
It is ground after 15-36 hours and obtains glutinous rice liquor, the weight ratio of the sterile water and glutinous rice is 3:1, the addition of distiller's yeast is dry glutinous rice
The 1-1.5% of weight;
(7) piemarker prepared by above-mentioned steps liquid 2-3 parts by weight, hawthorn extract 1-3 parts by weight, medicine parsley is produced to extract
Liquid 1-2 parts by weight, Radix Salviae Miltiorrhizae leaf extract 4-7 parts by weight, Radix Astragali extractive solution 1.5-4 parts by weight and self-control glutinous rice liquor 8-15 weight
Part, it is put into agitator tank and is mixed 10-15 minutes, then 24-36 hours are stood in 0-5 DEG C of environment, after spray drying
Powder processed obtained powdered cardiovascular health natural plant composition using ultraviolet disinfection 1-5 minutes.
The present invention has the advantages that compared with prior art:(1) the composition can melt in coronary artery
Existing thrombus softens blood vessel, improves coronary blood supply amount and oxygen-supplying amount, solves the problems, such as myocardial ischemia;(2) the composition can drop
Low blood pressure and blood fat, the root that removal coronary heart disease generates;(3) the composition reaches conditioning patient by blood-enrich, filling liver kidney
Body purpose;(4) food of integration of drinking and medicinal herbs is selected to prepare while having prevention, conditioning and treatment by scientific matching
The coronary heart disease health product of triple function;(5) product is directly prepared from natural materials, without any additive, instant-drink, mouth
Taste is mellow, is a kind of health drink.
Specific implementation mode:
The specific technical solution of the present invention is further described with reference to specific embodiment.
Embodiment 1:
The preparation method for the patients with coronary heart disease cardiovascular health natural plant composition that the present embodiment is related to, concrete technology
Process includes the following steps:
(1) piemarker produces liquid:The band shell piemarker seed for picking season in midsummer, then separates piemarker seed shell and piemarker seed,
First piemarker seed shell is put in the water of boiling leaching drift pull out immediately after five minutes be put into 10 DEG C of cold water cross wash cooling after smash to pieces;Again
It is ground into powdery after piemarker seed is fried, is then added in 5 times of water, decocts 3 hours in nonmetal pot, starched after cooling
Shape piemarker seed decocts slurries;The piemarker seed shell smashed to pieces and piemarker seed are decocted into 200 mesh press filtrations after slurries mix again, by filtrate
It is placed in conical flask with stopper, the weight percent concentration that 5 times of amounts are added is 75% ethanol water, is shaken in ultrasonator
Extraction 1 hour, supersonic frequency 100KHZ, then recycles ethyl alcohol with Rotary Evaporators, and the piemarker for obtaining a concentration of 2g/ml is produced
Liquid is spare;
(2) hawthorn extract:After the hawthorn picked screen, cleans, smashs to pieces after frost is beaten, in 8 times of water measured of addition
It stirs evenly, heating water bath, refluxing extraction 5 times at 70 DEG C, 2 hours every time, the filtering of 200 mesh will be merged by extracting solution each time,
Filtrate is concentrated into a concentration of 10g/L, obtains hawthorn extract, and powdered active carbon is added into hawthorn extract, in pH=
3.0, under the conditions of temperature is 60 DEG C, ultrasonic vibration decoloration 30-40min obtains a concentration of 5g/L hawthorn extracts;
(3) medicine parsley extracting solution:Picking fresh drug parsley is smashed to pieces after being impregnated 24 hours in 50 DEG C of warm water, is then added
The weight percent concentration of 7 times of amounts is to be stirred evenly in 75% ethanol water, and heating water bath flows back at a temperature of 75 DEG C and carries
Take 5 times, will each time extracting solution merge 200 mesh filtering after, be concentrated under reduced pressure, recycle ethyl alcohol, obtain a concentration of 3g/L medicines parsley and carry
Take liquid;
(4) Radix Salviae Miltiorrhizae leaf extract:It after Radix Salviae Miltiorrhizae leaf is dried, crushes, crosses 200 mesh sieve, be placed in conical flask with stopper, be added 3
The weight percent concentration of amount is 75% ethanol water again, and then concussion extraction 4h, supersonic frequency are in ultrasonator
120KHz, 200 mesh filter to take filtrate, and ethyl alcohol is recycled with Rotary Evaporators, under conditions of 3500rpm, centrifuge 15min, take
Clear liquid is concentrated under reduced pressure into a concentration of 4g/L, as Radix Salviae Miltiorrhizae leaf extract;
(5) Radix Astragali extractive solution:Radix Astragali is smashed to pieces, 3 times of amount water decoctions are then added and take decocting liquid within 2 hours, then add 2 times
Water, which decocts, takes decocting liquid for 1.5 hours, merges decocting liquid twice, is concentrated under reduced pressure under conditions of 0.05Mpa, 60 DEG C, weight is then added
Percent concentration is that 95% ethyl alcohol shakes extraction 4h in ultrasonator, obtains the Radix Astragali extractive solution of a concentration of 4g/L;
(6) glutinous rice liquor is made by oneself:Glutinous rice clear water is eluriated 4 times, is then impregnated 3 hours at 15 DEG C, then 5 are washed with clear water
Time, glutinous rice is cooked after draining away the water, sterile water and distiller's yeast are added after cooling, at 38 DEG C, ferment at constant temperature is ground after 36 hours
Obtain glutinous rice liquor, the weight ratio of the sterile water and glutinous rice is 3:1, the addition of distiller's yeast is the 1.5% of dry glutinous rice weight;
(7) piemarker prepared by above-mentioned steps is produced into 3 parts by weight of liquid, 3 parts by weight of hawthorn extract, medicine parsley extracting solution 2
Parts by weight, 7 parts by weight of Radix Salviae Miltiorrhizae leaf extract, 4 parts by weight of Radix Astragali extractive solution and self-control 15 parts by weight of glutinous rice liquor, are put into agitator tank
It is mixed 15 minutes, then stands 36 hours in 5 DEG C of environment, powder processed after spray drying divides using ultraviolet disinfection 5
Clock obtains powdered patients with coronary heart disease cardiovascular health natural plant composition.
The cardiovascular health natural plant composition that the present embodiment is related to is powdered, can directly be brewed, when brewing
60-75 DEG C of water is added, or 60-75 DEG C of milk is added, drinks in three times daily, each reference amount is 500-800ml, is taken
Period is no less than 2 months, most preferably 3-6 months, can reduce the total cholesterol in serum, soften blood vessel, turn down blood pressure, prevent
The aggregation of blood platelet and thrombosis have good therapeutic effect to coronary heart disease.
Embodiment 2:
The preparation method for the patients with coronary heart disease cardiovascular health natural plant composition that the present embodiment is related to, concrete technology
Process includes the following steps:
(1) piemarker produces liquid:The band shell piemarker seed for picking season in midsummer, then separates piemarker seed shell and piemarker seed,
Pulled out immediately after piemarker seed shell first being put in the water of boiling leaching drift 3 minutes be put into 5 DEG C of cold water cross wash cooling after smash to pieces;Again will
Piemarker seed is ground into powdery after frying, be then added in 5 times of water, decocted 2 hours in nonmetal pot, pulpous state is obtained after cooling
Piemarker seed decocts slurries;The piemarker seed shell smashed to pieces and piemarker seed are decocted into 200 mesh press filtrations after slurries mix again, filtrate is set
In conical flask with stopper, the weight percent concentration that 5 times of amounts are added is 75% ethanol water, shakes and carries in ultrasonator
It takes 1 hour, supersonic frequency 80KHZ, then recycles ethyl alcohol with Rotary Evaporators, the piemarker for obtaining a concentration of 2g/ml produces liquid
It is spare;
(2) hawthorn extract:After the hawthorn picked screen, cleans, smashs to pieces after frost is beaten, in 6 times of water measured of addition
It stirs evenly, heating water bath, refluxing extraction 3 times at 60 DEG C, 1 hour every time, the filtering of 200 mesh will be merged by extracting solution each time,
Filtrate is concentrated into a concentration of 10g/L, obtains hawthorn extract, and powdered active carbon is added into hawthorn extract, in pH=
3.0, under the conditions of temperature is 60 DEG C, ultrasonic vibration decoloration 30-40min obtains a concentration of 5g/L hawthorn extracts;
(3) medicine parsley extracting solution:Picking fresh drug parsley is smashed to pieces after being impregnated 18 hours in 48 DEG C of warm water, is then added
The weight percent concentration of 7 times of amounts is to be stirred evenly in 75% ethanol water, and heating water bath flows back at a temperature of 55 DEG C and carries
Take 3 times, will each time extracting solution merge 200 mesh filtering after, be concentrated under reduced pressure, recycle ethyl alcohol, obtain a concentration of 3g/L medicines parsley and carry
Take liquid;
(4) Radix Salviae Miltiorrhizae leaf extract:It after Radix Salviae Miltiorrhizae leaf is dried, crushes, crosses 200 mesh sieve, be placed in conical flask with stopper, be added 3
The weight percent concentration of amount is 75% ethanol water again, and then concussion extraction 2h, supersonic frequency are in ultrasonator
90KHz, 200 mesh filter to take filtrate, and ethyl alcohol is recycled with Rotary Evaporators, under conditions of 3500rpm, centrifuge 15min, take supernatant
Liquid is concentrated under reduced pressure into a concentration of 4g/L, as Radix Salviae Miltiorrhizae leaf extract;
(5) Radix Astragali extractive solution:Radix Astragali is smashed to pieces, 3 times of amount water decoctions are then added and take decocting liquid within 2 hours, then add 2 times
Water, which decocts, takes decocting liquid for 1.5 hours, merges decocting liquid twice, is concentrated under reduced pressure under conditions of 0.05Mpa, 60 DEG C, weight is then added
Percent concentration is that 95% ethyl alcohol shakes extraction 2-4h in ultrasonator, obtains the Radix Astragali extractive solution of a concentration of 4g/L;
(6) glutinous rice liquor is made by oneself:Glutinous rice clear water is eluriated 3 times, is then impregnated 2 hours at 15 DEG C, then 3 are washed with clear water
Time, glutinous rice is cooked after draining away the water, sterile water and distiller's yeast are added after cooling, at 30 DEG C, when ferment at constant temperature 15- after grind
To glutinous rice liquor, the weight ratio of the sterile water and glutinous rice is 3:1, the addition of distiller's yeast is the 1% of dry glutinous rice weight;
(7) piemarker prepared by above-mentioned steps is produced into 2 parts by weight of liquid, 1 parts by weight of hawthorn extract, medicine parsley extracting solution 1
Parts by weight, 4 parts by weight of Radix Salviae Miltiorrhizae leaf extract, 1.5 parts by weight of Radix Astragali extractive solution and self-control 8 parts by weight of glutinous rice liquor, are put into agitator tank
It is middle to be mixed 10 minutes, 24 hours then are stood in 0 DEG C of environment, powder processed after spray drying, using ultraviolet disinfection 1
Minute, obtain powdered cardiovascular health natural plant composition.
The cardiovascular health natural plant composition that the present embodiment is related to is powdered, can directly be brewed, when brewing
60-75 DEG C of water is added, or 60-75 DEG C of milk is added, drinks in three times daily, each reference amount is 500-800ml, is taken
Period is no less than 2 months, most preferably 3-6 months, can reduce the total cholesterol in serum, soften blood vessel, turn down blood pressure, prevent
The aggregation of blood platelet and thrombosis have good therapeutic effect to coronary heart disease.
Embodiment 3:
50 patients with coronary heart disease of composition powder foot couple that the present embodiment is prepared with embodiment 1 carry out health-care type treatment, wherein
The male patient 28 of selection, average age 55 years old, female patient 22, average age 60 years old, patient take naturally after morning and evening dinner daily
The drink 500-800ml that water or milk are configured to is added in plant composition.Efficacy assessment standard:(1) effective, pass through body after treatment
Matter enhances, and with it energetically, the symptoms such as feeling of oppression and pain in the chest, palpitation and uneasiness, heartbeat are overrun are relieved, and electrocardiogram restores normal or basic
Normally;(2) effectively, enhanced by constitution after treatment, with it energetically, the diseases such as feeling of oppression and pain in the chest, palpitation and uneasiness, heartbeat are overrun are delayed
Solution, attack times are reduced, and the intermittent phase extends, ECG ST section rise > t0.05mV or more, but not up to normal level, in master
Want that lead negative T wave resets or T popins are smooth becomes upright;(3) in vain, symptom is unchanged after treatment, after testing analysis of results table
It is bright:In selected 50 patients, effective 36, effective 11, invalid 3, wherein take three months has 9 with effective, clothes
And have after four months it is effective have 20, having after taking six months effective has 7.
Claims (1)
1. a kind of preparation method of cardiovascular health natural plant composition, which is characterized in that specific embodiment include with
Lower step:
(1) piemarker produces liquid:The band shell piemarker seed for picking season in midsummer, then separates piemarker seed shell and piemarker seed, first will
Piemarker seed shell put leaching drift in the water of boiling pulled out immediately after 3-5 minute in the cold water for be put into 5-10 DEG C cross wash cool down after smash to pieces;Again
It is ground into powdery after piemarker seed is fried, is then added in 5 times of water, decocts 2-3 hours in nonmetal pot, obtained after cooling
Pulpous state piemarker seed decocts slurries;The piemarker seed shell smashed to pieces and piemarker seed are decocted into 200 mesh press filtrations after slurries mix again, will be filtered
Liquid is placed in conical flask with stopper, and the weight percent concentration that 5 times of amounts are added is 75% ethanol water, is shaken in ultrasonator
Extraction 1 hour, supersonic frequency 80-100KHZ is swung, then ethyl alcohol is recycled with Rotary Evaporators, obtains the piemarker of a concentration of 2g/ml
It is spare that fiber crops produce liquid;
(2) hawthorn extract:After the hawthorn picked is screened, cleans, smashs to pieces after frost is beaten, stirred in the 6-8 times of water measured of addition
It mixes uniformly, heating water bath, refluxing extraction 3-5 times at 60-70 DEG C is 1-2 hours each, will merge 200 mesh by extracting solution each time
Filtering, filtrate are concentrated into a concentration of 10g/L, obtain hawthorn extract, powdered active carbon are added into hawthorn extract, in pH
=3.0, under the conditions of temperature is 60 DEG C, ultrasonic vibration decoloration 30-40min obtains a concentration of 5g/L hawthorn extracts;
(3) medicine parsley extracting solution:Picking fresh drug parsley is smashed to pieces after impregnating 18-24 hours in 48-50 DEG C of warm water, is then added
The weight percent concentration for entering 7 times of amounts is to be stirred evenly in 75% ethanol water, heating water bath, at a temperature of 55-75 DEG C
Refluxing extraction 3-5 times, will each time extracting solution merge 200 mesh filtering after, be concentrated under reduced pressure, recycle ethyl alcohol, obtain a concentration of 3g/L
Medicine parsley extracting solution;
(4) Radix Salviae Miltiorrhizae leaf extract:It after Radix Salviae Miltiorrhizae leaf is dried, crushes, crosses 200 mesh sieve, be placed in conical flask with stopper, 3 times of amounts are added
Weight percent concentration be 75% ethanol water, then in ultrasonator concussion extraction 2-4h, supersonic frequency 90-
120KHz, 200 mesh filter to take filtrate, and ethyl alcohol is recycled with Rotary Evaporators, under conditions of 3500rpm, centrifuge 15min, take
Clear liquid is concentrated under reduced pressure into a concentration of 4g/L, as Radix Salviae Miltiorrhizae leaf extract;
(5) Radix Astragali extractive solution:Radix Astragali is smashed to pieces, 3 times of amount water decoctions are then added and take decocting liquid within 2 hours, then add 2 times of decoctings
It boils and takes within 1.5 hours decocting liquid, merge decocting liquid twice, be concentrated under reduced pressure under conditions of 0.05Mpa, 60 DEG C, weight percent is then added
Specific concentration is that 95% ethyl alcohol shakes extraction 2-4h in ultrasonator, obtains the Radix Astragali extractive solution of a concentration of 4g/L;
(6) glutinous rice liquor is made by oneself:Glutinous rice clear water is eluriated 3-4 times, is then impregnated 2-3 hours at 5-15 DEG C, then washed with clear water
It washs 3-5 times, cooks glutinous rice after draining away the water, sterile water and distiller's yeast, at 30-38 DEG C, ferment at constant temperature 15-36 are added after cooling
It is ground after hour and obtains glutinous rice liquor, the weight ratio of the sterile water and glutinous rice is 3:1, the addition of distiller's yeast is dry glutinous rice weight
1-1.5%;
(7) piemarker prepared by above-mentioned steps is produced into liquid 2-3 parts by weight, hawthorn extract 1-3 parts by weight, medicine parsley extracting solution 1-
2 parts by weight, Radix Salviae Miltiorrhizae leaf extract 4-7 parts by weight, Radix Astragali extractive solution 1.5-4 parts by weight and self-control glutinous rice liquor 8-15 parts by weight, put
Enter to be mixed in agitator tank 10-15 minutes, then stands 24-36 hours in 0-5 DEG C of environment, powder processed after spray drying,
Using ultraviolet disinfection 1-5 minutes, powdered cardiovascular health natural plant composition is obtained.
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