CN108309925A - A kind of trichogenous cosmetic composition and its application - Google Patents
A kind of trichogenous cosmetic composition and its application Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/002—Preparations for repairing the hair, e.g. hair cure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/006—Antidandruff preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/008—Preparations for oily hair
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/12—Preparations containing hair conditioners
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/82—Preparation or application process involves sonication or ultrasonication
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
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Abstract
The present invention discloses a kind of trichogenous cosmetic composition, is prepared via a method which to obtain：1) 5 20 parts of Radix Angelicae Sinensis, 15 parts of ginseng, 1 10 parts of Rhizoma Gastrodiae, 1 10 parts of red clover, 1 10 parts of black wild cherry fruit, 15 parts of dateplum persimmon, 10 30 parts of maize, 0.01 0.1 parts of lactobacillus are taken；2) Radix Angelicae Sinensis, ginseng, Rhizoma Gastrodiae, red clover, black wild cherry fruit, dateplum persimmon, maize are mixed, is dried, crushed, sift out, obtain mixed raw material；3) mixed raw material is mixed with mountain spring water；4) lactobacillus is added into the mixed raw material, ferments 10 40 hours, obtains fermented product；5) ultrasonic wave extraction is carried out to the fermented product, obtains solid-liquid product；6) the solid-liquid product stood, filtered, sterilized, take filtrate, obtain the trichogenous cosmetic composition.The present invention can make scalp function normalization, promote scalp blood circulation, enhance hair follicle function, nourish hair quality, have and promote hair regeneration, keep hair health and other effects.
Description
Technical field
The present invention relates to cosmetic fields, and in particular to a kind of trichogenous cosmetic composition and its application.
Background technology
The hair of human body has about 100,000-15 ten thousand or so, is formed in " hair follicle ".Hair follicle has nipple, is distributed at the position
Thin vessels, the nutritional ingredient needed for hair growth is supplied, grease of the side above nipple there is supply for moistening hair
Cortex gland.Each hair has the mutually different period, by growth period (anagen), catagen (catagen), stand-down
(telogen) it grows and falls off.Such period by 3-6 and repeatedly, averagely has 50-100 root hairs normally to take off daily
It falls.Usually signified baldness is because the ratio of anagen hair is short, and catagen or stand-down hair are more, the hair to fall off
Number it is extremely more caused by.The reason of as alopecia, what is often lifted includes that male hormones effect surplus is said, sebum divides
Secrete it is superfluous says, poor circulation is said, the scalp function reduction caused by peroxide, bacterium etc. is said, gene factor, always
Change, pressure etc..Specifically, it is referred to as 5α-reductase (5 α-as a kind of testosterone (testosteron) of male hormones
Reductase ferment activation) is dihydrotestosterone (dihydrotestoserone；DHT).The DHT and special receptor in conjunction with and
The protein for causing alopecia is induced, alopecia is caused.Also, it is based on this mechanism, superfluous sebum can be generated, cause acne or fat
Atopic dermatitis etc. is leaked, occurs the alopecia with inflammation on scalp.
Up to now, there is minoxidil as the drug for having Anti-hair loss, promotion hair tonic and hair growth effect
(minoxidil), mucopolysaccharide auxin (trichosaccharide) and Finasteride (finasteride) etc..Minoxidil
Initially as treatment hypertension vasodilator and develop, but because its be reported cause hirsutism side effect and by
It is developed as hair restorer.The mechanism of action of the hair-growing effects of minoxidil is not yet completely clear, it is contemplated that have, due to blood vessel
Nutrition supply caused by expansion increases, potassium channel opens (potassiumchannelpening) effect and papilla
(dermalpapillacells) Apoptosis (apoptosis) inhibits effect to induce hair growth.In addition, in Merck
(Merck) Finasteride developed in is the active substance for the 5α-reductase for inhibiting to play a role in male sex hormone is metabolized.
Originally, it is developed as the therapeutic agent for the treatment of prostatism, promotes hair growth because it is reported afterwards, and is developed as hair tonic
Medicine.In the case of this preparation, adjuvant and human body stability, the initiation skin of remarkable efficacy pierce the side-effect problems such as hair and show
It is existing, need to develop a kind of stability and the reliable composition of effect.
Invention content
The technical problem to be solved in the present invention is to provide a kind of trichogenous cosmetic compositions.
The specific technical solution for solving above-mentioned technical problem is as follows：
A kind of trichogenous cosmetic composition, the trichogenous cosmetic composition pass through as follows
Method is prepared：1) 5-20 parts of Radix Angelicae Sinensis, 1-5 parts of ginseng, 1-10 parts of Rhizoma Gastrodiae, 1-10 parts of red clover, black wild cherry fruit 1-10 are taken
Part, 1-5 parts of dateplum persimmon, 10-30 parts of maize, 0.01-0.1 parts of lactobacillus；2) by Radix Angelicae Sinensis, ginseng, Rhizoma Gastrodiae, red clover, black wild cherry
Fruit, dateplum persimmon, maize mixing, dry, crush, sift out, obtain mixed raw material；3) mixed raw material is mixed with mountain spring water；4) to
Lactobacillus is added in the mixed raw material, ferments 10-40 hours, obtains fermented product；5) ultrasound is carried out to the fermented product
Wave extracts, and obtains solid-liquid product；6) the solid-liquid product stood, filtered, sterilized, take filtrate, obtain the promotion hair
Long cosmetic composition occurs.
Further, in the step 2), the mesh number of the sieve is 100-200 mesh.It, can be more between mesh number 100-200
Good to be reacted with lactic acid bacteria, the active constituent of extraction is purer.
Further, in the step 3), the additive amount of the mountain spring water is 1-3 times of mixed raw material weight.Work as mountain
It when the additive amount of spring is 1-3 times of mixed raw material weight, can fully be mixed with mixed raw material, form reticular structure, preferably
It penetrates into Chinese medicine cell.
Further, in the step 4), the bacterial content of the lactobacillus is 1 × 106-1×108cfu/mL.The present invention adopts
With lactobacillus-fermented, composition stability obtained is good, has significant hair quality improvement result, especially bacterial content is 1 × 106-1
×108It is small to the irritation of scalp when cfu/mL.
Further, in the step 4), the fermentation carries out in terrine at a temperature of 35 DEG C -40 DEG C.This hair
It is bright to be fermented using terrine vessel, fermentation vessel are made compared to stainless steel, terrine permeability is good, and opaque, can more fully send out
Ferment.
Further, in the step 5), the condition of the ultrasonic wave extraction is：Temperature is 45 DEG C -55 DEG C；Frequency is
15-25KHz；Time is 3-5 minutes.The present invention is extracted using the method for ultrasonic wave extraction, can greatly improve composition
The yield of active constituent, and there is energy saving, efficient good effect.
Further, in the step 6), the solid-liquid product stands 1-3 days under the conditions of 3-5 DEG C, then uses 5000-
10000 mesh filter-cloth filterings.
The present invention also provides application of the trichogenous cosmetic composition in preparing cosmetics,
In, the dosage of the trichogenous cosmetic composition is the 0.1-10wt% of final products weight.
A kind of hair conditioner includes each component of following mass percentage：Above-mentioned trichogenous cosmetic combinations
Object 0.1-10%, Xylitol-based glucoside 0.1-1%, hydrolecithin 0.01-0.5%, hydrogenated olive oil unsaponifiable matter 0.01-
0.2%, hydrogenated olive oil acid ethylhexyl 0.1-2%, cetostearyl alcohol 0.5-3%, polysorbate -200.1-1%, poly- season
Ammonium salt -371-3%, PPG-1 tridecanol polyethers -60.1-0.5%, propylene/dicaprate 0.01-0.3%, VP/
VA copolymers 0.01-0.3%, carbonic acid dioctyl ester 0.1-1%, polyalcohol 5-15%, hydrolyzed pearl 0.1-0.5%, dehydration xylose
Alcohol 0.5-1%, xylitol 1-2%, EDETATE SODIUM 0.01-0.05%, preservative 0.1-1%, water surplus.
Further, the polyalcohol is at least one of glycerine, 1,2- butanediols, propylene glycol, sorbierite.
Further, the preservative is at least one of Phenoxyethanol, potassium sorbate, sodium benzoate.
The present invention has the advantages that：
The present composition is mixed by Radix Angelicae Sinensis, ginseng, Rhizoma Gastrodiae, red clover, black wild cherry fruit, dateplum persimmon, maize plurality of Chinese
It is made, transdermal effect can be increased, by expanded head capillary, promote blood circulation, promotion plays hair growth non-
The growing multiplication of the dermal papilla cell of normal important role induces or maintains the growth period of hair follicle, have keep hair thicker and
The effect of new hair is generated, ensure natural on-off cycles of hair growth and keeps hair submissive and is not easy to become fragile, additionally it is possible to improve the tensile strength of hair
And extensibility, keep hair to lubricate gloss.Using lactobacillus-fermented combination ultrasonic wave extraction, can improve composition it is effective at
Point, further promote the growth of hair.Hair conditioner provided by the invention has hair restoring and curing, strengthen the hair anticreep, repairs scalp cells
And hair follicle, pigment and the anti-dandruff effect synchronously completed of oil-control are supplemented, can make that root of hair is firm, hair quality is submissive smooth.
Specific implementation mode
To make the object, technical solutions and advantages of the present invention clearer, embodiment of the present invention will be made into one below
Step ground detailed description, embodiments of the present invention are not limited thereto, for not specifically specified technological parameter or condition, can refer to
Routine techniques carries out.
Radix Angelicae Sinensis:Blood circulation promoting and dispersing pathogen accumulation dredging collateral can expand the capillary of scalp and skin, promote blood circulation.
Ginseng：Promote the transfer of hair cycle stand-down to anagen hair period, so as to provide the life for promoting hair
Effect that is long, preventing hair loss.
In Rhizoma Gastrodiae contain a large amount of amino acid, amino acid to cranial nerve be metabolized and liver beneficial to benefit act on, to it is antifatigue,
Promote digestive system, promote skin health, natural on-off cycles of hair growth, has the function of additive.
Red clover (Trifolium pretense L) is legume, and alias is also referred to as red clover, red clover,
Red Holland Astragalus sinicuses.Red clover contains the ingredients such as Flavonoid substances, protein, amino acid, carbohydrate and vitamin.Make with sterilization
With, have preferable inhibition to scurf Bacillus (Pityrosporumovale), can be used for inhibit scalp grease.
Black wild cherry fruit has good moisture-keeping efficacy, provides nutrition to scalp, hair is kept to lubricate gloss.
Dateplum persimmon is rich in vitamin and iron, has effects that blood-nourishing bowl spares.
Maize exists《Essential Recipes for Emergent Use Worth A Thousand Gold》Described in：" support kidney qi, heumatism of dispelling, bowl spares, QI invigorating." during all alopecias, white hair belong to
Unsaturated vapor, speen-kidney dificiency person can use it.
" alopecia " refers to that the phenomenon that hair falls off from scalp or hair become the state dredged or attenuated." Anti-hair loss " refers to preventing
With inhibition depilation phenomenon as described above." promoting hair growth " refers not only to promote new hair growth, also refers to existing hair
Healthily grow.
Growth period, catagen, this 3 key steps of stand-down can be divided into hair cycle.It is fast with cell in growth period
Speed proliferation, hair follicle form hair toward deeply growth inside skin.Next phenomenon is catagen, it is that fissional interrupt shows
The transitional period of work, in this process, the gradual regression of hair follicle, hair growth interrupt.In the stand-down of next phenomenon, regression hair follicle packet
Containing the plumule (germ) for having densely intensive papilla (dermalpapilla) cell.In stand-down, new growth period
Phenomenon is initially by the expansion of the quick cell Proliferation, papilla of the plumule and synthesizing and inducing for basilar memebrane element
's.
In general, " hair growth " was formed in growth period, by induction from stand-down to growth period and from growth period to
The delay of catagen and promote.Then, the promotion or extension by growth period are needed, trichomadesis is prevented, prevents hair loss, or
Person induces the regrowth of hair, promotes hair growth.
The composition of the present invention has and the improvements such as does not make the effect of existing trichomadesis, keeps existing hair thicker
And generate the effect of new hair.In addition, the composition of the present invention activates dermal papilla cell and induced hair growth.
Embodiment 1
A kind of hair conditioner includes each component of following mass percentage：Trichogenous cosmetic composition
0.1%, Xylitol-based glucoside 1%, hydrolecithin 0.01%, hydrogenated olive oil unsaponifiable matter 0.2%, hydrogenated olive oil acid
Ethylhexyl 0.1%, cetostearyl alcohol 3%, polysorbate -200.1%, polyquaternium -373%, PPG-1 tridecanols are poly-
Ether -60.1%, propylene/dicaprate 0.3%, VP/VA copolymers 0.3%, carbonic acid dioctyl ester 1%, glycerine
5%, hydrolyzed pearl 0.5%, anhydro xylitol 1%, xylitol 2%, EDETATE SODIUM 0.05%, potassium sorbate 1%, water surplus.
The trichogenous cosmetic composition is prepared via a method which to obtain：1) 20 parts of Radix Angelicae Sinensis, ginseng 5 are taken
Part, 10 parts of Rhizoma Gastrodiae, 1 part of red clover, 10 parts of black wild cherry fruit, 1 part of dateplum persimmon, 10 parts of maize, 0.1 part of lactobacillus；2) by Radix Angelicae Sinensis, people
Ginseng, Rhizoma Gastrodiae, red clover, black wild cherry fruit, dateplum persimmon, maize mixing, dry, crush, sieve with 100 mesh sieve son, obtain mixed raw material；3)
The mountain spring water that mixed raw material is measured with 1 times is mixed；4) lactobacillus is added into the mixed raw material, ferments in terrine in 40 DEG C
40 hours, obtain fermented product；5) ultrasonic wave extraction is carried out to the fermented product, obtains solid-liquid product；6) to the solid-liquid
Product stand 1 day under the conditions of 5 DEG C then with 10000 mesh filter-cloth filterings, sterilizing, take filtrate, obtain the promotion hair growth
Cosmetic composition.
The bacterial content of the lactobacillus is 1 × 106cfu/mL。
The condition of the ultrasonic wave extraction is：Temperature is 55 DEG C；Frequency is 25KHz；Time is 5 minutes.
Embodiment 2
A kind of hair conditioner includes each component of following mass percentage：Trichogenous cosmetic composition
10%, Xylitol-based glucoside 0.1%, hydrolecithin 0.5%, hydrogenated olive oil unsaponifiable matter 0.01%, hydrogenated olive oil
Sour ethylhexyl 2%, cetostearyl alcohol 0.5%, polysorbate -201%, polyquaternium -371%, PPG-1 tridecanols are poly-
Ether -60.5%, propylene/dicaprate 0.01%, VP/VA copolymers 0.01%, carbonic acid dioctyl ester 0.1%, 1,
2- butanediols 15%, hydrolyzed pearl 0.1%, anhydro xylitol 0.5%, xylitol 1%, EDETATE SODIUM 0.01%, sodium benzoate
0.1%, water surplus.
The trichogenous cosmetic composition is prepared via a method which to obtain：1) 5 parts of Radix Angelicae Sinensis, ginseng 1 are taken
Part, 1 part of Rhizoma Gastrodiae, 10 parts of red clover, 1 part of black wild cherry fruit, 5 parts of dateplum persimmon, 30 parts of maize, 0.01 part of lactobacillus；2) by Radix Angelicae Sinensis, people
Ginseng, Rhizoma Gastrodiae, red clover, black wild cherry fruit, dateplum persimmon, maize mixing, dry, crush, cross 200 mesh sieve, obtain mixed raw material；3)
The mountain spring water that mixed raw material is measured with 3 times is mixed；4) lactobacillus is added into the mixed raw material, ferments in terrine in 35 DEG C
10 hours, obtain fermented product；5) ultrasonic wave extraction is carried out to the fermented product, obtains solid-liquid product；6) to the solid-liquid
Product stand 3 days under the conditions of 3 DEG C then with 5000 mesh filter-cloth filterings, sterilizing, take filtrate, obtain the promotion hair growth
Cosmetic composition.
The bacterial content of the lactobacillus is 1 × 108cfu/mL。
The condition of the ultrasonic wave extraction is：Temperature is 45 DEG C；Frequency is 15KHz；Time is 3 minutes.
Embodiment 3
A kind of hair conditioner includes each component of following mass percentage：Trichogenous cosmetic composition
5%, Xylitol-based glucoside 0.5%, hydrolecithin 0.3%, hydrogenated olive oil unsaponifiable matter 0.1%, hydrogenated olive oil acid
Ethylhexyl 1%, cetostearyl alcohol 2%, polysorbate -200.5%, polyquaternium -372%, PPG-1 tridecanols polyethers -
60.3%, propylene/dicaprate 0.2%, VP/VA copolymers 0.2%, carbonic acid dioctyl ester 0.5%, sorbierite
10%, hydrolyzed pearl 0.3%, anhydro xylitol 0.8%, xylitol 1.5%, EDETATE SODIUM 0.03%, Phenoxyethanol 0.5%,
Water surplus.
The trichogenous cosmetic composition is prepared via a method which to obtain：1) 12 parts of Radix Angelicae Sinensis, ginseng 3 are taken
Part, 5 parts of Rhizoma Gastrodiae, 6 parts of red clover, 4 parts of black wild cherry fruit, 3 parts of dateplum persimmon, 20 parts of maize, 0.05 part of lactobacillus；2) by Radix Angelicae Sinensis, people
Ginseng, Rhizoma Gastrodiae, red clover, black wild cherry fruit, dateplum persimmon, maize mixing, dry, crush, cross 150 mesh sieve, obtain mixed raw material；3)
The mountain spring water that mixed raw material is measured with 2 times is mixed；4) lactobacillus is added into the mixed raw material, ferments in terrine in 38 DEG C
25 hours, obtain fermented product；5) ultrasonic wave extraction is carried out to the fermented product, obtains solid-liquid product；6) to the solid-liquid
Product stand 2 days under the conditions of 4 DEG C then with 8000 mesh filter-cloth filterings, sterilizing, take filtrate, obtain the promotion hair growth
Cosmetic composition.
The bacterial content of the lactobacillus is 1 × 107cfu/mL。
The condition of the ultrasonic wave extraction is：Temperature is 50 DEG C；Frequency is 20KHz；Time is 4 minutes.
Embodiment 4
A kind of hair conditioner includes each component of following mass percentage：Trichogenous cosmetic composition
4%, Xylitol-based glucoside 0.6%, hydrolecithin 0.2%, hydrogenated olive oil unsaponifiable matter 0.15%, hydrogenated olive oil acid
Ethylhexyl 0.5%, cetostearyl alcohol 1%, polysorbate -200.3%, polyquaternium -371.5%, PPG-1 tridecanols are poly-
Ether -60.4%, propylene/dicaprate 0.1%, VP/VA copolymers 0.1%, carbonic acid dioctyl ester 0.2%, the third two
Alcohol 13%, hydrolyzed pearl 0.4%, anhydro xylitol 0.7%, xylitol 1.8%, EDETATE SODIUM 0.02%, sodium benzoate
0.5%, water surplus.
The trichogenous cosmetic composition is prepared via a method which to obtain：1) 10 parts of Radix Angelicae Sinensis, ginseng 2 are taken
Part, 6 parts of Rhizoma Gastrodiae, 4 parts of red clover, 5 parts of black wild cherry fruit, 2 parts of dateplum persimmon, 25 parts of maize, 0.06 part of lactobacillus；2) by Radix Angelicae Sinensis, people
Ginseng, Rhizoma Gastrodiae, red clover, black wild cherry fruit, dateplum persimmon, maize mixing, dry, crush, cross 120 mesh sieve, obtain mixed raw material；3)
The mountain spring water that mixed raw material is measured with 2 times is mixed；4) lactobacillus is added into the mixed raw material, ferments in terrine in 35 DEG C
20 hours, obtain fermented product；5) ultrasonic wave extraction is carried out to the fermented product, obtains solid-liquid product；6) to the solid-liquid
Product stand 2 days under the conditions of 5 DEG C then with 7000 mesh filter-cloth filterings, sterilizing, take filtrate, obtain the promotion hair growth
Cosmetic composition.
The bacterial content of the lactobacillus is 1 × 107cfu/mL。
The condition of the ultrasonic wave extraction is：Temperature is 50 DEG C；Frequency is 25KHz；Time is 3 minutes.
Embodiment 5
A kind of hair conditioner includes each component of following mass percentage：Trichogenous cosmetic composition
8%, Xylitol-based glucoside 0.7%, hydrolecithin 0.4%, hydrogenated olive oil unsaponifiable matter 0.05%, hydrogenated olive oil acid
Ethylhexyl 0.6%, cetostearyl alcohol 0.8%, polysorbate -200.9%, polyquaternium -372.5%, PPG-1 tridecanols
Polyethers -60.2%, propylene/dicaprate 0.15%, VP/VA copolymers 0.02%, carbonic acid dioctyl ester 0.4%,
Sorbierite 4%, propylene glycol 4%, hydrolyzed pearl 0.4%, anhydro xylitol 0.8%, xylitol 1.8%, EDETATE SODIUM 0.03%,
Phenoxyethanol 0.7%, water surplus.
The trichogenous cosmetic composition is prepared via a method which to obtain：1) 8 parts of Radix Angelicae Sinensis, ginseng 2 are taken
Part, 2 parts of Rhizoma Gastrodiae, 3 parts of red clover, 2 parts of black wild cherry fruit, 4 parts of dateplum persimmon, 22 parts of maize, 0.02 part of lactobacillus；2) by Radix Angelicae Sinensis, people
Ginseng, Rhizoma Gastrodiae, red clover, black wild cherry fruit, dateplum persimmon, maize mixing, dry, crush, cross 140 mesh sieve, obtain mixed raw material；3)
The mountain spring water that mixed raw material is measured with 3 times is mixed；4) lactobacillus is added into the mixed raw material, ferments in terrine in 40 DEG C
30 hours, obtain fermented product；5) ultrasonic wave extraction is carried out to the fermented product, obtains solid-liquid product；6) to the solid-liquid
Product stand 2 days under the conditions of 3 DEG C then with 6000 mesh filter-cloth filterings, sterilizing, take filtrate, obtain the promotion hair growth
Cosmetic composition.
The bacterial content of the lactobacillus is 1 × 106cfu/mL。
The condition of the ultrasonic wave extraction is：Temperature is 45 DEG C；Frequency is 20KHz；Time is 4 minutes.
Embodiment 6
A kind of hair conditioner includes each component of following mass percentage：Trichogenous cosmetic composition
3%, Xylitol-based glucoside 0.4%, hydrolecithin 0.3%, hydrogenated olive oil unsaponifiable matter 0.03%, hydrogenated olive oil acid
Ethylhexyl 0.7%, cetostearyl alcohol 2.5%, polysorbate -200.7%, polyquaternium -372%, PPG-1 tridecanols are poly-
Ether -60.4%, propylene/dicaprate 0.2%, VP/VA copolymers 0.2%, carbonic acid dioctyl ester 0.8%, glycerine
6%, sorbierite 6%, hydrolyzed pearl 0.4%, anhydro xylitol 0.8%, xylitol 1.5%, EDETATE SODIUM 0.03%, sorbic acid
Potassium 0.8%, water surplus.
The trichogenous cosmetic composition is prepared via a method which to obtain：1) 18 parts of Radix Angelicae Sinensis, ginseng 4 are taken
Part, 8 parts of Rhizoma Gastrodiae, 7 parts of red clover, 9 parts of black wild cherry fruit, 2 parts of dateplum persimmon, 15 parts of maize, 0.08 part of lactobacillus；2) by Radix Angelicae Sinensis, people
Ginseng, Rhizoma Gastrodiae, red clover, black wild cherry fruit, dateplum persimmon, maize mixing, dry, crush, cross 180 mesh sieve, obtain mixed raw material；3)
The mountain spring water that mixed raw material is measured with 1 times is mixed；4) lactobacillus is added into the mixed raw material, ferments in terrine in 38 DEG C
35 hours, obtain fermented product；5) ultrasonic wave extraction is carried out to the fermented product, obtains solid-liquid product；6) to the solid-liquid
Product stand 2 days under the conditions of 4 DEG C then with 9000 mesh filter-cloth filterings, sterilizing, take filtrate, obtain the promotion hair growth
Cosmetic composition.
The bacterial content of the lactobacillus is 1 × 108cfu/mL。
The condition of the ultrasonic wave extraction is：Temperature is 50 DEG C；Frequency is 15KHz；Time is 5 minutes.
Comparative example 1
The difference is that, comparative example 1 is not added with Radix Angelicae Sinensis with embodiment 3.
Comparative example 2
The difference is that, comparative example 2 is not added with ginseng with embodiment 3.
Comparative example 3
The difference is that, comparative example 3 is not added with Rhizoma Gastrodiae with embodiment 3.
Comparative example 4
The difference is that, comparative example 4 is not added with red clover with embodiment 3.
Comparative example 5
The difference is that, comparative example 5 is not added with black wild cherry fruit with embodiment 3.
Comparative example 6
The difference is that, comparative example 6 is not added with dateplum persimmon with embodiment 3.
Comparative example 7
The difference is that, comparative example 7 is not added with maize with embodiment 3.
In order to show that the product of the present invention has trichogenous effect, 325 alopecia patients, age are selected
25-55 Sui, average age 32 years old, wherein male 150 people, 175 people of female, are divided into 13 groups, every group of 25 people, each group uses embodiment respectively
The hair conditioner of 1-6, comparative example 1-7.Daily using primary.It persistently uses 2-3 months, it is average every two weeks to the hair number of subject
Amount, hair density, hair fineness degree carry out observation statistics.
Test result is as shown in table 1：
As shown in Table 1, hair conditioner of the invention can be obviously promoted hair restoration, alleviate alopecia symptom, and make original head
Send out thicker.
Comparative example 1-7 is with embodiment 1-6 comparisons as it can be seen that Radix Angelicae Sinensis, ginseng, Rhizoma Gastrodiae, red clover, black wild cherry fruit, dateplum persimmon, grain
Rice is that hair conditioner promotes hair restoration, alleviation alopecia symptom, and the key component for keeping original hair thicker, and Radix Angelicae Sinensis, ginseng, day
The effect of hair conditioner is just apparent when fiber crops, red clover, black wild cherry fruit, dateplum persimmon, maize share, and embodies synergistic function.
The above described is only a preferred embodiment of the present invention, limitation in any form not is done to the present invention, therefore
All contents without departing from technical solution of the present invention, it is made to the above embodiment according to the technical essence of the invention any simply to repair
Change, equivalent variations and modification, in the range of still falling within technical solution of the present invention.
Claims (10)
1. a kind of trichogenous cosmetic composition, which is characterized in that the trichogenous cosmetic combinations
Object is prepared via a method which to obtain：1) 5-20 parts of Radix Angelicae Sinensis, 1-5 parts of ginseng, 1-10 parts of Rhizoma Gastrodiae, 1-10 parts of red clover, black is taken
1-10 parts of wild cherry fruit, 1-5 parts of dateplum persimmon, 10-30 parts of maize, 0.01-0.1 parts of lactobacillus；2) by Radix Angelicae Sinensis, ginseng, Rhizoma Gastrodiae, screw oil expeller axis
Careless, black wild cherry fruit, dateplum persimmon, maize mixing, dry, crush, sift out, obtain mixed raw material；3) by mixed raw material and mountain spring water
Mixing；4) lactobacillus is added into the mixed raw material, ferments 10-40 hours, obtains fermented product；5) to the fermented product
Ultrasonic wave extraction is carried out, solid-liquid product is obtained；6) the solid-liquid product stood, filtered, sterilized, take filtrate, obtain institute
State trichogenous cosmetic composition.
2. trichogenous cosmetic composition according to claim 1, which is characterized in that in the step 2),
The mesh number of the sieve is 100-200 mesh.
3. trichogenous cosmetic composition according to claim 1, which is characterized in that in the step 3),
The additive amount of the mountain spring water is 1-3 times of mixed raw material weight.
4. trichogenous cosmetic composition according to claim 1, which is characterized in that in the step 4),
The bacterial content of the lactobacillus is 1 × 106-1×108cfu/mL。
5. trichogenous cosmetic composition according to claim 1, which is characterized in that in the step 4),
The fermentation carries out in terrine at a temperature of 35 DEG C -40 DEG C.
6. trichogenous cosmetic composition according to claim 1, which is characterized in that in the step 5),
The condition of the ultrasonic wave extraction is：Temperature is 45 DEG C -55 DEG C；Frequency is 15-25KHz；Time is 3-5 minutes.
7. trichogenous cosmetic composition according to claim 1, which is characterized in that in the step 6),
The solid-liquid product stands 1-3 days under the conditions of 3-5 DEG C, then uses 5000-10000 mesh filter-cloth filterings.
8. according to the trichogenous cosmetic composition of claim 1-7 any one of them answering in preparing cosmetics
With, wherein the dosage of the trichogenous cosmetic composition is the 0.1-10wt% of final products weight.
9. a kind of hair conditioner, which is characterized in that include each component of following mass percentage：Such as any one of claim 1-7
The trichogenous cosmetic composition 0.1-10%, Xylitol-based glucoside 0.1-1%, hydrolecithin
0.01-0.5%, hydrogenated olive oil unsaponifiable matter 0.01-0.2%, hydrogenated olive oil acid ethylhexyl 0.1-2%, cetearyl alcohol
Alcohol 0.5-3%, polysorbate -200.1-1%, polyquaternium -371-3%, PPG-1 tridecanol polyethers -60.1-0.5%, third
It is glycol dicaprylate/dicaprate 0.01-0.3%, VP/VA copolymer 0.01-0.3%, carbonic acid dioctyl ester 0.1-1%, polynary
Alcohol 5-15%, hydrolyzed pearl 0.1-0.5%, anhydro xylitol 0.5-1%, xylitol 1-2%, EDETATE SODIUM 0.01-0.05%,
Preservative 0.1-1%, water surplus.
10. a kind of hair conditioner according to claim 9, which is characterized in that the polyalcohol be glycerine, 1,2- butanediols,
At least one of propylene glycol, sorbierite；The preservative is at least one of Phenoxyethanol, potassium sorbate, sodium benzoate.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810413501.0A CN108309925A (en) | 2018-04-29 | 2018-04-29 | A kind of trichogenous cosmetic composition and its application |
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| CN201810413501.0A CN108309925A (en) | 2018-04-29 | 2018-04-29 | A kind of trichogenous cosmetic composition and its application |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112022788A (en) * | 2020-10-19 | 2020-12-04 | 上海珈凯生物科技有限公司 | Anti-hair loss plant extract and preparation method and application thereof |
| CN112076130A (en) * | 2020-10-11 | 2020-12-15 | 广州莱约生物科技有限公司 | Hair-growing and anti-hair loss composition and preparation method and application thereof |
| FR3125419A1 (en) * | 2021-07-23 | 2023-01-27 | L'oreal | hair styling compositions and methods |
-
2018
- 2018-04-29 CN CN201810413501.0A patent/CN108309925A/en not_active Withdrawn
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112076130A (en) * | 2020-10-11 | 2020-12-15 | 广州莱约生物科技有限公司 | Hair-growing and anti-hair loss composition and preparation method and application thereof |
| CN112022788A (en) * | 2020-10-19 | 2020-12-04 | 上海珈凯生物科技有限公司 | Anti-hair loss plant extract and preparation method and application thereof |
| FR3125419A1 (en) * | 2021-07-23 | 2023-01-27 | L'oreal | hair styling compositions and methods |
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