CN108309896A - A kind of hair care anti-hair loss composition and its application - Google Patents
A kind of hair care anti-hair loss composition and its application Download PDFInfo
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- CN108309896A CN108309896A CN201810413544.9A CN201810413544A CN108309896A CN 108309896 A CN108309896 A CN 108309896A CN 201810413544 A CN201810413544 A CN 201810413544A CN 108309896 A CN108309896 A CN 108309896A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/12—Preparations containing hair conditioners
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
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Abstract
The invention discloses a kind of hair care anti-hair loss composition and its applications, include the component of following parts by weight:0.1 10 parts of Folium eriobotryae, 0.1 10 parts of English walnut.The hair care anti-hair loss composition of the present invention is through a large amount of experiment and research of inventor, selected Folium eriobotryae, English walnut, and obtain its optimum proportioning, this kind of composition obtained is safe and non-toxic, with very strong 5 alpha-reductase active function of inhibition, and the metabolism of scalp cells can be promoted, increase scalp blood microcirculation, to inhibit the synthesis of this specific male hormones of DHT, the seborrheic alopecia caused by the property of male sex hormone source is effectively treated;Rhizoma anemarrhenae is compounded with safflower, and the deep enough hair follicle of energy forms filter net type protecting film, and control hair follicle greasy dirt secretion prevents repiece falling out, especially compounds Folium eriobotryae, English walnut, is conducive to hair follicle stimulating, activation scalp cells, and reinforce blood circulation, promotes newborn.
Description
Technical field
The present invention relates to daily chemicals fields, and in particular to a kind of hair care anti-hair loss composition and its application.
Background technology
The reason of about alopecia, different types of alopecia be summed up caused by different pathogenic factors, including
The following aspects:(1) the related hair follicle underactivity of male sex hormone.Head hair is strictly influenced by male sex hormone, man
The stosterone of sex hormone becomes Viability higher 5 α-dihydrotestosterones (DHT), this change at hair follicle through 5α-reductase catalysis
Change is irreversible.DHT is the main reason for causing alopecia, it can be combined with intracellular receptor protein, be transferred to cell
In core, by specific gene activation, the specific protein of inductive formation to hinder the growth of hair, and then generates permanent
The alopecia of property or baldness.(2) hair follicle, ball top portion and hair physiological function are low.Hair is grown from hair follicle bottom, and hair follicle bottom
There are many cell divided on the papilla in portion, they are ball tops, and ball top is the originator of hair, is had in the episphere of ball top
Chromatophore, their common effects are secretion greases, moisten hair.When fat secretion surplus, then can cause to generate seborrheica
Alopecia, or cause bacterium to generate alopecia furfuracea disease.(3) local blood circulation obstacle caused by scalp anxiety, causes hair
Capsule, papilla the flow of tip capillary reduce, the food materials of papilla and hair matricyte are insufficient, make hair
Growth occurs abnormal.(4) malnutritive, stress reaction and drug side-effect.(5) inherent cause etc..
In Chinese early stage, people tackle alopecia, and the Chinese traditional herbs of China are usually used, with the prescription of folk medicine,
Based on folk prescription, or using the multiple action putting on the skin, apply, the phase of an eclipse combines, by hair follicle stimulating, promotion blood microcirculation provides hair
The means such as growth nutrient, to have the function that phalacrosis prevention and hair generation.But general procedure is more cumbersome, and pungent stimulation is heavier, at present
Seldom it is used.
Generally acknowledge that most effective treatment male sex hormone alopecia method is topical minoxidil lotion and oral Finasteride at present.
It studies according to the experiment, in the in vitro culture of hair follicle, when minoxidil (minuodier), which is added, can increase the growth of culture hair follicle
Between.Minoxidil stimulation maintains hair follicle growth and extends the hair follicle growth phase, and the hair follicle development of microminiaturization is made to increase and promote hair breast
Cephalic artery is formed and function, to play an important role in hair growth.Finasteride (Finasteride) is a kind of 4- azepines
Steroidal compounds, it is testosterone metabolism as the desmoenzyme-II type 5α-reductases during stronger 5 α-dihydrotestosterones
Specific inhibitor.But it is hirsutism that minoxidil, which has scalp certain irritation, main adverse reaction, and exist secondary
Effect;Finasteride has heredity and genotoxicity.
Invention content
The technical problem to be solved in the present invention is to provide a kind of hair care anti-hair loss composition and its applications.
The specific technical solution for solving above-mentioned technical problem is as follows:
A kind of hair care anti-hair loss composition, includes the component of following parts by weight:0.1-10 parts of Folium eriobotryae, 0.1-10 parts of English walnut.
Further, the hair care anti-hair loss composition further includes the component of following parts by weight:0.1-10 parts of rhizoma anemarrhenae, safflower
0.1-10 parts.
Further, the preparation method of the hair care anti-hair loss composition includes the following steps:It, will by parts by weight described above
Composition is dried, and is mixed, and is crushed, is obtained mixture, and the volume fraction that 10-15 times of weight is added by the weight of mixture is 45-
55% ethanol water after cold soaking, under the conditions of 80-90 DEG C, extracts in vacuum decompression return tank, obtains extracting solution, will carry
It takes liquid to be filtered through ceramic composite membrane microfiltration equipment, obtains filtrate, then by after filtrate Cord blood 2-3 days, filter-cloth filtering must be clarified
Liquid, you can.
Further, the grain size of the crushing is 100-400 mesh.
Further, the time of the cold soaking is 1-3h.
Further, the pore diameter of the ceramic composite membrane is 80-150nm.
Further, the low temperature is 3-5 DEG C.
Further, the aperture of the filter cloth is 300-800 mesh.
The present invention obtains active ingredient using ceramic composite membrane microfiltration equipment, and active constituent therein retains more, miscellaneous
Matter is less.Ceramic composite membrane microfiltration equipment can the macromolecular substances such as effectively catching protein, fat, when product being avoided to place for a long time
The association of macromolecular substances generates precipitation.The preparation method of present invention hair care anti-hair loss composition is easy to operate, obtained group
Close object does not have stimulation to scalp.
The present invention also provides application of the hair care anti-hair loss composition in preparing cosmetics, wherein the hair care is anti-
The dosage of de- composition is the 0.1-10wt% of final products weight.
A kind of anticreep shampoo, includes the component of following mass percentage:Above-mentioned hair care anti-hair loss composition 0.1-10%,
Sodium lauroyl sarcosine 5-15%, Cocoamidopropyl betaine 5-10%, Plantacare 818 3-8%, coconut oleoyl amine methyl MEA
1-5%, rosemary (ROSMARINUS OFFICINALIS) leaf oil 0.01-1%, Butyrospermum parkii (BUTYROSPERMUM
PARKII) wooden (LEPTOSPERMUM PETERSONII) oil 0.01-1% of the thin son of fruit fat 0.01-1%, Magnus Petersson, hydrolysed corn
The smooth caprylate 0.1-1% of starch 0.1-1%, sorb, hydrolecithin 0.01-0.2%, glycerine 0.1-3%, PPG-3 Octyl Ether
0.01-0.1%, guar hydroxypropyltrimonium chloride 0.05-0.5%, piroctone olamine salt 0.01-0.1%, bay
Alcohol polyethers -30.01-0.1%, sodium benzoate 0.1-0.3%, Phenoxyethanol 0.1-0.3%, EDETATE SODIUM 0.01-0.1%, water
Surplus.
The present invention has the advantages that:
The hair care anti-hair loss composition of the present invention is obtained through a large amount of experiment and research of inventor, selected Folium eriobotryae, English walnut
This kind of composition of its optimum proportioning, acquisition is safe and non-toxic, has very strong inhibition 5α-reductase active function, and can promote
Into the metabolism of scalp cells, increase scalp blood microcirculation has to inhibit the synthesis of this specific male hormones of DHT
Effect treatment seborrheic alopecia caused by the property of male sex hormone source;Rhizoma anemarrhenae is compounded with safflower, can deep enough hair follicle formation strainer
Formula protecting film, control hair follicle greasy dirt secretion, prevents repiece falling out, especially compounds Folium eriobotryae, English walnut, is conducive to stimulate hair
Capsule activates scalp cells, and reinforces blood circulation, promotes newborn.
It is applied in shampoo, is effectively improved scalp nutritional status, nourish scalp, promote natural on-off cycles of hair growth, avoid patient
Because of the side effect that drug therapy is brought, it can prevent and treat, be free from side effects when baldness starts to occur, target user
Extensively, effect protrudes.
Specific implementation mode
To make the object, technical solutions and advantages of the present invention clearer, embodiment of the present invention will be made into one below
Step ground detailed description, embodiments of the present invention are not limited thereto, for not specifically specified technological parameter or condition, can refer to
Routine techniques carries out.
Folium eriobotryae is the leaf of rosaceous plant loquat Eriobotrya japonica (Thunb.) Lindl..Containing saponin(e, bear
Tartaric acid, oleanolic acid, vitamin C and tannin isoreactivity ingredient, are commonly used to removing heat from the lung to relieve cough, stopping nausea and vomiting by lowering the adverse flow of QI.Dry can be treated to quench one's thirst,
Lung wind face sore, acne.Modern pharmacological research report confirms that it, with preferable anti-inflammatory, antibacterial and antitussive action, is frequently used for treating
Acne and remove acne cosmeceutical.
English walnut:It invigorates the kidney and stops nocturnal emission, warm lung cough-relieving, nourishing qi and blood, brain-nourishing intelligence-benefiting relaxes bowel.
Rhizoma anemarrhenae:Main to contain saponin, rhizome contains total saposins about 6%, has good decontamination, removes grease ability, this spy
Property enable it to deep enough hair follicle and form filter net type protecting film, control hair follicle greasy dirt secretion.
Safflower:It is warm-natured, acrid flavour, invigorate blood circulation, removing blood stasis and analgesics.
The present invention compounds rhizoma anemarrhenae and safflower, and the deep enough hair follicle of energy forms filter net type protecting film, controls the secretion of hair follicle greasy dirt,
Repiece falling out is prevented, Folium eriobotryae, English walnut are especially compounded, is conducive to hair follicle stimulating, activates scalp cells, and reinforce blood and follow
Ring promotes newborn.
Embodiment 1
A kind of anticreep shampoo, includes the component of following mass percentage:Hair care anti-hair loss composition 10%, lauroyl flesh
Propylhomoserin sodium 5%, Cocoamidopropyl betaine 10%, Plantacare 818 3%, coconut oleoyl amine methyl MEA5%, rosemary
(ROSMARINUS OFFICINALIS) leaf oil 1%, Butyrospermum parkii (BUTYROSPERMUM PARKII) fruit fat 0.01%, Peter
Pine thin son wooden (LEPTOSPERMUM PETERSONII) oil 1%, hydrolysed corn starch 0.1%, the smooth caprylate 1% of sorb, hydrogenation
Lecithin 0.01%, glycerine 3%, PPG-3 Octyl Ethers 0.01%, guar hydroxypropyltrimonium chloride 0.5%, piroctone
Ethanolamine salt 0.01%, laureth -30.1%, sodium benzoate 0.1%, Phenoxyethanol 0.3%, EDETATE SODIUM 0.01%,
Water surplus.
The hair care anti-hair loss composition is made of 0.1 part of Folium eriobotryae, 10 parts of English walnut.
The preparation method of the hair care anti-hair loss composition includes the following steps:It is mixed by 0.1 part of Folium eriobotryae, 10 parts of English walnut,
It dry, pulverize, obtain mixture, the ethanol water that the volume fraction of 15 times of weight is 45% is added by the weight of mixture, it is cold
It after leaching, under the conditions of 90 DEG C, is extracted in vacuum decompression return tank, obtains extracting solution, extracting solution is set through Ceramic Composite membrane microfiltration
Standby filtering, obtains filtrate, then by after filtrate Cord blood 2 days, filter-cloth filtering obtains clarified solution, you can.
Further, the grain size of the crushing is 400 mesh.
Further, the time of the cold soaking is 1h.
Further, the pore diameter of the ceramic composite membrane is 150nm.
Further, the low temperature is 3 DEG C.
Further, the aperture of the filter cloth is 800 mesh.
Embodiment 2
A kind of anticreep shampoo, includes the component of following mass percentage:Hair care anti-hair loss composition 0.1%, lauroyl
Sodium sarcosinate 15%, Cocoamidopropyl betaine 5%, Plantacare 818 8%, coconut oleoyl amine methyl MEA1%, rosemary
(ROSMARINUS OFFICINALIS) leaf oil 0.01%, Butyrospermum parkii (BUTYROSPERMUM PARKII) fruit fat 1%, Peter
Pine thin son wooden (LEPTOSPERMUM PETERSONII) oil 0.01%, hydrolysed corn starch 1%, the smooth caprylate 0.1% of sorb,
Hydrolecithin 0.2%, glycerine 0.1%, PPG-3 Octyl Ethers 0.1%, guar hydroxypropyltrimonium chloride 0.05%, pyrrole
Rock ketone ethanolamine salt 0.1%, laureth -30.01%, sodium benzoate 0.3%, Phenoxyethanol 0.1%, EDETATE SODIUM
0.1%, water surplus.
The hair care anti-hair loss composition is made of 10 parts of Folium eriobotryae, 0.1 part of English walnut.
The preparation method of the hair care anti-hair loss composition includes the following steps:It is mixed by 10 parts of Folium eriobotryae, 0.1 part of English walnut,
It dry, pulverize, obtain mixture, the ethanol water that the volume fraction of 10 times of weight is 55% is added by the weight of mixture, it is cold
It after leaching, under the conditions of 80 DEG C, is extracted in vacuum decompression return tank, obtains extracting solution, extracting solution is set through Ceramic Composite membrane microfiltration
Standby filtering, obtains filtrate, then by after filtrate Cord blood 3 days, filter-cloth filtering obtains clarified solution, you can.
Further, the grain size of the crushing is 100 mesh.
Further, the time of the cold soaking is 3h.
Further, the pore diameter of the ceramic composite membrane is 80nm.
Further, the low temperature is 5 DEG C.
Further, the aperture of the filter cloth is 300 mesh.
Embodiment 3
A kind of anticreep shampoo, includes the component of following mass percentage:Hair care anti-hair loss composition 5%, lauroyl flesh
Propylhomoserin sodium 10%, Cocoamidopropyl betaine 7%, Plantacare 818 5%, coconut oleoyl amine methyl MEA3%, rosemary
(ROSMARINUS OFFICINALIS) leaf oil 0.5%, Butyrospermum parkii (BUTYROSPERMUM PARKII) fruit fat 0.5%, that
Obtain loose thin son wooden (LEPTOSPERMUM PETERSONII) oil 0.5%, hydrolysed corn starch 0.5%, the smooth caprylate of sorb
0.5%, hydrolecithin 0.1%, glycerine 2%, PPG-3 Octyl Ethers 0.05%, guar hydroxypropyltrimonium chloride
0.3%, piroctone olamine salt 0.05%, laureth -30.05%, sodium benzoate 0.2%, Phenoxyethanol 0.2%,
EDETATE SODIUM 0.05%, water surplus.
The hair care anti-hair loss composition is made of 5 parts of Folium eriobotryae, 5 parts of English walnut.
The preparation method of the hair care anti-hair loss composition includes the following steps:By 5 parts of 5 parts of Folium eriobotryae, English walnut mixing, do
It is dry, it crushes, obtains mixture, the ethanol water that the volume fraction of 13 times of weight is 50%, cold soaking is added by the weight of mixture
Afterwards, it under the conditions of 85 DEG C, is extracted in vacuum decompression return tank, obtains extracting solution, by extracting solution through ceramic composite membrane microfiltration equipment
Filtering, obtains filtrate, then by after filtrate Cord blood 2 days, filter-cloth filtering obtains clarified solution, you can.
Further, the grain size of the crushing is 300 mesh.
Further, the time of the cold soaking is 2h.
Further, the pore diameter of the ceramic composite membrane is 120nm.
Further, the low temperature is 4 DEG C.
Further, the aperture of the filter cloth is 500 mesh.
Embodiment 4
A kind of anticreep shampoo, includes the component of following mass percentage:Hair care anti-hair loss composition 5%, lauroyl flesh
Propylhomoserin sodium 10%, Cocoamidopropyl betaine 7%, Plantacare 818 5%, coconut oleoyl amine methyl MEA3%, rosemary
(ROSMARINUS OFFICINALIS) leaf oil 0.5%, Butyrospermum parkii (BUTYROSPERMUM PARKII) fruit fat 0.5%, that
Obtain loose thin son wooden (LEPTOSPERMUM PETERSONII) oil 0.5%, hydrolysed corn starch 0.5%, the smooth caprylate of sorb
0.5%, hydrolecithin 0.1%, glycerine 1.5%, PPG-3 Octyl Ethers 0.05%, guar hydroxypropyltrimonium chloride
0.3%, piroctone olamine salt 0.05%, laureth -30.05%, sodium benzoate 0.2%, Phenoxyethanol 0.2%,
EDETATE SODIUM 0.05%, water surplus.
The hair care anti-hair loss composition is made of 5 parts of Folium eriobotryae, 5 parts of English walnut, 4 parts of rhizoma anemarrhenae, 6 parts of safflower.
The preparation method of the hair care anti-hair loss composition includes the following steps:By 5 parts of Folium eriobotryae, 5 parts of English walnut, 4 parts of rhizoma anemarrhenae,
6 parts of mixing of safflower, dry, pulverize, obtain mixture, and the second that the volume fraction of 12 times of weight is 50% is added by the weight of mixture
Alcohol solution after cold soaking, under the conditions of 85 DEG C, extracts in vacuum decompression return tank, obtains extracting solution, and extracting solution is multiple through ceramics
The filtering of membrane microfiltration equipment is closed, obtains filtrate, then by after filtrate Cord blood 3 days, filter-cloth filtering obtains clarified solution, you can.
Further, the grain size of the crushing is 200 mesh.
Further, the time of the cold soaking is 2h.
Further, the pore diameter of the ceramic composite membrane is 100nm.
Further, the low temperature is 4 DEG C.
Further, the aperture of the filter cloth is 600 mesh.
Embodiment 5
A kind of anticreep shampoo, includes the component of following mass percentage:Hair care anti-hair loss composition 3%, lauroyl flesh
Propylhomoserin sodium 8%, Cocoamidopropyl betaine 8%, Plantacare 818 4%, coconut oleoyl amine methyl MEA4%, rosemary
(ROSMARINUS OFFICINALIS) leaf oil 0.3%, Butyrospermum parkii (BUTYROSPERMUM PARKII) fruit fat 0.8%, that
Obtain loose thin son wooden (LEPTOSPERMUM PETERSONII) oil 0.2%, hydrolysed corn starch 0.7%, the smooth caprylate of sorb
0.2%, hydrolecithin 0.05%, glycerine 1%, PPG-3 Octyl Ethers 0.08%, guar hydroxypropyltrimonium chloride
0.4%, piroctone olamine salt 0.09%, laureth -30.07%, sodium benzoate 0.2%, Phenoxyethanol 0.3%,
EDETATE SODIUM 0.07%, water surplus.
The hair care anti-hair loss composition is made of 2 parts of Folium eriobotryae, 7 parts of English walnut, 0.1 part of rhizoma anemarrhenae, 10 parts of safflower.
The preparation method of the hair care anti-hair loss composition includes the following steps:By 2 parts of Folium eriobotryae, 7 parts of English walnut, rhizoma anemarrhenae 0.1
10 parts of part, safflower mixing, dry, pulverize, obtain mixture, the volume fraction that 10 times of weight is added by the weight of mixture is 55%
Ethanol water, after cold soaking, under the conditions of 80 DEG C, extracted in vacuum decompression return tank, obtain extracting solution, by extracting solution through pottery
Porcelain composite membrane microfiltration equipment filters, and obtains filtrate, then by after filtrate Cord blood 2 days, filter-cloth filtering obtains clarified solution, you can.
Further, the grain size of the crushing is 100 mesh.
Further, the time of the cold soaking is 3h.
Further, the pore diameter of the ceramic composite membrane is 130nm.
Further, the low temperature is 5 DEG C.
Further, the aperture of the filter cloth is 700 mesh.
Embodiment 6
A kind of anticreep shampoo, includes the component of following mass percentage:Hair care anti-hair loss composition 8%, lauroyl flesh
Propylhomoserin sodium 12%, Cocoamidopropyl betaine 6%, Plantacare 818 4%, coconut oleoyl amine methyl MEA2%, rosemary
(ROSMARINUS OFFICINALIS) leaf oil 0.7%, Butyrospermum parkii (BUTYROSPERMUM PARKII) fruit fat 0.4%, that
Obtain loose thin son wooden (LEPTOSPERMUM PETERSONII) oil 0.9%, hydrolysed corn starch 0.6%, the smooth caprylate of sorb
0.8%, hydrolecithin 0.15%, glycerine 2.5%, PPG-3 Octyl Ethers 0.04%, guar hydroxypropyltrimonium chloride
0.25%, piroctone olamine salt 0.02%, laureth -30.08%, sodium benzoate 0.2%, Phenoxyethanol 0.2%,
EDETATE SODIUM 0.06%, water surplus.
The hair care anti-hair loss composition is made of 8 parts of Folium eriobotryae, 3 parts of English walnut, 10 parts of rhizoma anemarrhenae, 0.1 part of safflower.
The preparation method of the hair care anti-hair loss composition includes the following steps:By 8 parts of Folium eriobotryae, 3 parts of English walnut, rhizoma anemarrhenae 10
0.1 part of part, safflower mixing, dry, pulverize, obtain mixture, and the volume fraction that 12 times of weight are added by the weight of mixture is
48% ethanol water after cold soaking, under the conditions of 84 DEG C, extracts in vacuum decompression return tank, obtains extracting solution, by extracting solution
It is filtered through ceramic composite membrane microfiltration equipment, obtains filtrate, then by after filtrate Cord blood 3 days, filter-cloth filtering obtains clarified solution, you can.
Further, the grain size of the crushing is 300 mesh.
Further, the time of the cold soaking is 2h.
Further, the pore diameter of the ceramic composite membrane is 140nm.
Further, the low temperature is 4 DEG C.
Further, the aperture of the filter cloth is 400 mesh.
Comparative example 1
The difference is that, comparative example 1 is not added with Folium eriobotryae with embodiment 3.
Comparative example 2
The difference is that, comparative example 2 is not added with English walnut with embodiment 3.
Comparative example 3
The difference is that, comparative example 3 is not added with rhizoma anemarrhenae with embodiment 4.
Comparative example 4
The difference is that, comparative example 4 is not added with safflower with embodiment 4.
Experimental example 1
In order to show that the product of the present invention has the effect of anticreep of taking care of hair, 250 alopecia patients, age 25-55 are selected
Year, average age 32 years old are divided into 10 groups wherein male 150 people, 100 people of female, every group of 25 people, each group use respectively embodiment 1-6,
The anticreep shampoo of comparative example 1-4.Wash a hair daily.It persistently uses 2-3 months, it is average every two weeks to the hair of subject
Quantity, hair density carry out observation statistics.Test result is as shown in table 1:
The ratio that subject's epilation number significantly reduces | Subject's alopecia area regrows the region of hair | |
Embodiment 1 | 75% | 65% |
Embodiment 2 | 78% | 68% |
Embodiment 3 | 83% | 72% |
Embodiment 4 | 98% | 85% |
Embodiment 5 | 95% | 83% |
Embodiment 6 | 95% | 82% |
Comparative example 1 | 20% | 10% |
Comparative example 2 | 25% | 8% |
Comparative example 3 | 84% | 63% |
Comparative example 4 | 83% | 64% |
As shown in Table 1, anticreep shampoo of the invention can be relieved alopecia symptom, and excite hair regeneration, anticreep
Hair-growing effects are notable.
Comparative example 1-2 alleviates alopecia symptom with embodiment 1-3 comparisons as it can be seen that Folium eriobotryae, English walnut are anticreep shampoos, and swashs
It is scared to send out key component regenerated, and when Folium eriobotryae, English walnut share anticreep shampoo effect it is just apparent, embody synergy
Effect.
Embodiment 4-6 is with embodiment 1-3 comparisons as it can be seen that the addition of rhizoma anemarrhenae, safflower significantly improves the anticreep hair washing
Water alleviates alopecia symptom, and excites the effect of hair regeneration;And comparative example 3-4 and embodiment 4-6 is compared as it can be seen that rhizoma anemarrhenae, safflower
Promotion effect can be just embodied when sharing, and have the function of synergy.
The above described is only a preferred embodiment of the present invention, limitation in any form not is done to the present invention, therefore
All contents without departing from technical solution of the present invention, it is made to the above embodiment according to the technical essence of the invention any simply to repair
Change, equivalent variations and modification, in the range of still falling within technical solution of the present invention.
Claims (10)
1. a kind of hair care anti-hair loss composition, which is characterized in that include the component of following parts by weight:0.1-10 parts of Folium eriobotryae, English walnut
0.1-10 parts.
2. a kind of hair care anti-hair loss composition according to claim 1, which is characterized in that the hair care anti-hair loss composition also wraps
Include the component of following parts by weight:0.1-10 parts of rhizoma anemarrhenae, 0.1-10 parts of safflower.
3. a kind of hair care anti-hair loss composition according to claim 1 or 2, which is characterized in that the hair care anti-hair loss composition
Preparation method include the following steps:By parts by weight described in claims 1 or 2, composition is mixed, dry, pulverize, must be mixed
Object, the volume fraction that 10-15 times of weight is added by the weight of mixture is the ethanol water of 45-55%, after cold soaking, in 80-
It under the conditions of 90 DEG C, is extracted in vacuum decompression return tank, obtains extracting solution, extracting solution is filtered through ceramic composite membrane microfiltration equipment,
Filtrate is obtained, then by after filtrate Cord blood 2-3 days, filter-cloth filtering obtains clarified solution, you can.
4. a kind of hair care anti-hair loss composition according to claim 3, which is characterized in that the grain size of the crushing is 100-
400 mesh.
5. a kind of hair care anti-hair loss composition according to claim 3, which is characterized in that the time of the cold soaking is 1-
3h。
6. a kind of hair care anti-hair loss composition according to claim 3, which is characterized in that the pore diameter of the ceramic composite membrane
For 80-150nm.
7. a kind of hair care anti-hair loss composition according to claim 3, which is characterized in that the low temperature is 3-5 DEG C.
8. a kind of hair care anti-hair loss composition according to claim 3, which is characterized in that the aperture of the filter cloth is 300-
800 mesh.
9. described according to a kind of application of the hair care anti-hair loss composition of claim 1-4 any one of them in preparing cosmetics
The dosage of hair care anti-hair loss composition is the 0.1-10wt% of final products weight.
10. a kind of anticreep shampoo, which is characterized in that include the component of following mass percentage:As claim 1-8 is any
Described in hair care anti-hair loss composition 0.1-10%, sodium lauroyl sarcosine 5-15%, Cocoamidopropyl betaine 5-10%,
Plantacare 818 3-8%, coconut oleoyl amine methyl MEA 1-5%, rosemary (ROSMARINUS OFFICINALIS) leaf oil 0.01-
1%, the thin sub- wood (LEPTOSPERMUM of Butyrospermum parkii (BUTYROSPERMUM PARKII) fruit fat 0.01-1%, Magnus Petersson
PETERSONII) oil 0.01-1%, hydrolysed corn starch 0.1-1%, the smooth caprylate 0.1-1% of sorb, hydrolecithin 0.01-
0.2%, glycerine 0.1-3%, PPG-3 Octyl Ethers 0.01-0.1%, guar hydroxypropyltrimonium chloride 0.05-0.5%, pyrrole
Rock ketone ethanolamine salt 0.01-0.1%, laureth -30.01-0.1%, sodium benzoate 0.1-0.3%, Phenoxyethanol
0.1-0.3%, EDETATE SODIUM 0.01-0.1%, water surplus.
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CN201810413544.9A CN108309896A (en) | 2018-04-29 | 2018-04-29 | A kind of hair care anti-hair loss composition and its application |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110613627A (en) * | 2019-10-25 | 2019-12-27 | 上海中医药大学 | Cosmetic and preparation method thereof |
CN112569159A (en) * | 2021-01-04 | 2021-03-30 | 广州瑞誉化工科技有限公司 | Hair loss preventing and caring composition, hair caring essence and preparation method thereof |
-
2018
- 2018-04-29 CN CN201810413544.9A patent/CN108309896A/en not_active Withdrawn
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110613627A (en) * | 2019-10-25 | 2019-12-27 | 上海中医药大学 | Cosmetic and preparation method thereof |
CN112569159A (en) * | 2021-01-04 | 2021-03-30 | 广州瑞誉化工科技有限公司 | Hair loss preventing and caring composition, hair caring essence and preparation method thereof |
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