CN108294147A - 一种用于减脂降糖的中药保健制剂 - Google Patents
一种用于减脂降糖的中药保健制剂 Download PDFInfo
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- CN108294147A CN108294147A CN201810291503.7A CN201810291503A CN108294147A CN 108294147 A CN108294147 A CN 108294147A CN 201810291503 A CN201810291503 A CN 201810291503A CN 108294147 A CN108294147 A CN 108294147A
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Abstract
本发明公开了一种用于减脂降糖的中药保健组合物，是以乌梅、葛根、莲子、枸杞子、黑芝麻、大豆低聚糖、魔芋精粉、左旋肉碱、大豆分离蛋白为原料药，按药剂学的常规工艺和辅料制备成的内服制剂，或按保健食品或食品的加工工艺加工成保健食品制剂或食品制剂。临床统计数据表明，本发明的中药保健制剂具有明显的减肥作用，而且还可用于超重和肥胖并发症的综合治理，尤其是对于肥胖者的血糖具有很好的调理作用。另外，本发明采用药食同源、无毒无副作用的药材和食材为原料，长期服食，还具有非常好的养生作用。
Description
技术领域
本发明涉及一种用于减肥的中药保健制剂，尤其涉及一种用于减脂降糖的中药保健制剂，属于中药保健领域。
背景技术
肥胖和超重是困扰现代人健康问题与外在形象问题的最为严重的事件。由于食物摄入过多或机体代谢的改变而导致体内脂肪积聚过多造成体重过度增长并引起人体病理、生理改变或潜伏。肥胖不是一般的身体臃肿，而是一种威胁人类健康的慢性疾病，是一切亚健康与疾病的温床（身体多余的脂肪绑架了组织器官，而且挤占了正常生理结构的位置），而且是一种公害和瘟疫（当下人们已经习惯了肥胖的事实）。因此，一旦肥胖，其多余的脂肪24小时不间断、全天候对人体脏腑组织器官、皮毛四肢百骸进行挤压、绑架、侵害，最终导致并发症层出不穷。比如肥胖症的并发症之一高血糖，其血糖持续维持高值的结果将是二次对人体造成全方位的打击。
发明内容
本发明的目的是提供一种用于减肥降脂的中药保健制剂，其既能起到减肥的作用，又兼具调理血糖的功效。
本发明的中药保健制剂，以乌梅、葛根、莲子、枸杞子、黑芝麻、大豆低聚糖、魔芋精粉、左旋肉碱、大豆分离蛋白为原料药进行组方配伍，使各组分功效产生协同，共凑敛肺涩肠、生津安蛔、清热解毒、补脾益肾、养阴润燥、标本兼施、减脂康体、平调血糖之功能。
乌梅，酸、涩、平，归肝、脾、肺、大肠经，具有敛肺，涩肠，生津，安蛔之功效。作为君药，生津敛肺以调节血糖，安蛔杀虫以调节肠道微生物，继而调节脂肪吸收过多问题。
葛根，甘、辛、凉，有解肌退热、透疹、生津止渴、升阳止泻之功。莲子，甘、温，入脾、肾、心经，清心醒脾、补脾止泻、养心安神、健脾补胃、止泻固精、益肾止带、滋补元气。葛根、莲子同为臣药，邪正并举，一方面减肥降脂，一方面补虚康体，为君药助一臂之力。
枸杞子，甘、平。归肝、肾经，滋补肝肾、益精明目。黑芝麻，甘、平，归肝、肾、大肠经，补肝肾、益精血、润肠燥。枸杞子、黑芝麻同为佐药，重在养阴治本，让肥胖的产生无源。
大豆低聚糖，不仅低热量高营养，可以营养康体，而且通便洁肠，促进肠道内双歧杆菌增殖，降低血清胆固醇，保护肝脏，抑制肠内腐败物质的生成。魔芋精粉，不仅属于碱性食品，而且有减肥健身、治病抗癌功效。左旋肉碱，不仅属于类维生素、类氨基酸，对人体营养康体功劳卓著，而且可以促进脂肪转化成能量。大豆分离蛋白，具有高蛋白、低脂、高钙、降胆固醇特点，并含有人体必需氨基酸。大豆低聚糖、魔芋精粉、左旋肉碱、大豆分离蛋白同为使药，以补虚、平衡营养为己任，配合君臣佐药，直达目标。
本发明的中药保健制剂中，各原料药按以下重量份进行配比：乌梅24~28份、葛根13~16份、莲子13~16份、枸杞子8~11份、黑芝麻8~11份、大豆低聚糖3~6份、魔芋精粉3~6份、左旋肉碱3~6份、大豆分离蛋白3~6份。
优选配比：乌梅26份、葛根15份、莲子15份、枸杞子10份、黑芝麻10份、大豆低聚糖6份、魔芋精粉6份、左旋肉碱6份、大豆分离蛋白6份。
本发明的中药保健制剂，可按药剂学的常规工艺和辅料制备成的内服制剂如茶剂、颗粒剂、软胶囊剂等。也可按保健食品或食品的加工工艺加工成保健食品以及食品如代餐饼干、代餐粉、茶剂、压片糖果剂、方便食品剂、休闲食品剂等。
下面通过临床资料来进一步说明本发明中药保健制剂的减肥和降糖效果。
1.对象与方法
1.1试验物
采用本发明茶剂，规格：80g/袋，60袋/盒。由兰州古驰生物科技有限公司提供。
1.2受试对象
我们在兰州地区观察了自2015-2017三年间，对伴有糖尿病的肥胖症患者共82例，年龄在30-75岁之间，其中女性38例，男性44例。
1.2.1诊断标准
疲乏无力，随机血糖高于11.1mmol/L，被确诊为糖尿病的患者的真正肥胖者。真正肥胖者的评定标准：肥胖度超过10%，称之为超重。肥胖度超过20%-30%，称之为轻度肥胖。肥胖度超过30%-50%，称之为中度肥胖。肥胖度超过50%以上，称之为重度肥胖。我们只将真正肥胖者（含轻、中、高度肥胖者）纳入观察对象。
1.2.2纳入者标准：上述自愿受试者，经体检合格者。
1.3使用方法
用法：早晚代餐，各1袋，用温开水溶解后服食。疗程：3月1周期，一般观察3周期。
2.观察指标
2.1一般情况
既往病史，现病史，饮食，心率，血压。主要观察：并发症等情况。
2.2实验室指标
血常规、尿常规、粪常规、生化指标、B超（腹部）、心电图、X线胸部透视。
2.3体重指标
痊愈：体重和血糖值恢复至正常标准且随访半年未反弹者。显效：减去超额体重的40%以上、血糖值恢复至正常或明显改善。有效：减去超额体重的20%以上、血糖值明显得到改善者。无效：减去超额体重的20%（不含20%）以下、血糖值没有明显改善者。
2.4其它依据
虽体重无变化但八围（颈围、臂围、胃围、腹围、下腹围、臀围、上股围、下股围）缩小了。
3.试验结果
3.1一般情况
受试组如原无异常临床表现者在90天观察后未见异常。受试组如试验前心率过快，脂肪肝，血压、血脂、血尿酸偏高者经90天观察后均有不同程度的好转。
3.2实验指标
受试组如原无血常规、尿常规、粪常规、生化指标、B超（腹部）、心电图、X线胸部透视异常者在试验后均无异常变化。受试组在试验前如血脂偏高、有脂肪肝、有胆囊炎、有痔疮者等则有不同程度的缓解趋势。
3.3体重指标
治疗观察90天后进行统计。痊愈29例，占35.4%；显效31例，占37.8%；有效19例，占23.2%；无效3例，占3.7 %。总有效率96.3 %。
4.结论
上述临床统计数据表明，本发明的中药保健制剂具有明显的减肥作用，而且还可用于超重和肥胖并发症的综合治理，尤其是对于肥胖者的血糖具有很好的调理作用。另外，本发明采用药食同源、无毒无副作用的药材和食材为原料，长期服食，还具有非常好的养生作用。
具体实施方式
下面通过具体实施例对本发明中药保健制剂的原料配比及制备做进一步说明。
实施例1、茶剂的制备
原料配方：乌梅26份、葛根15份、莲子15份、枸杞子10份、黑芝麻10份、大豆低聚糖6份、魔芋精粉6份、左旋肉碱6份、大豆分离蛋白6份。
制备工艺：按制备茶剂的常规工艺和辅料制备成。规格：80g/袋，60袋/盒。
使用方法：一日2次，一次1袋。疗程：3月1周期，一般观察3周期。
实施例2、颗粒剂的制备
原料配方：乌梅24份、葛根13份、莲子13份、枸杞子8份、黑芝麻8份、大豆低聚糖3份、魔芋精粉3份、左旋肉碱3份、大豆分离蛋白3份。
制备工艺：按药剂学或保健食品制备颗粒剂的常规工艺和辅料制备而成。每袋80g。
使用方法：一日2次，每次1袋，用温开水溶解后服食。疗程：3月1周期，一般观察3周期。
实施例3、营养代餐饼干的制备
原料配方：乌梅28份、葛根16份、莲子16份、枸杞子11份、黑芝麻11份、大豆低聚糖6份、魔芋精粉6份、左旋肉碱6份、大豆分离蛋白6份。
制备工艺：按食品制备饼干的常规工艺和辅料制备而成。规格：80g/袋，60袋/盒。
使用方法：早晚代餐，各1袋，直接食用或用温开水溶解后服食。疗程：3月1周期，一般观察3周期。
上述各实施例中，各原料的配比均以重量份计。
Claims (5)
1.一种用于减脂降糖的中药保健组合物，是以乌梅、葛根、莲子、枸杞子、黑芝麻、大豆低聚糖、魔芋精粉、左旋肉碱、大豆分离蛋白为原料药，按药剂学的常规工艺和辅料制备成的内服制剂，或按保健食品或食品的加工工艺加工成保健食品制剂或食品制剂。
2.如权利要求1所述一种用于减脂降糖的中药保健组合物，其特征在于：所述各原料药按以下述重量份进行配比：乌梅24~28份、葛根13~16份、莲子13~16份、枸杞子8~11份、黑芝麻8~11份、大豆低聚糖3~6份、魔芋精粉3~6份、左旋肉碱3~6份、大豆分离蛋白3~6份。
3.如权利要求1所述一种用于减脂降糖的中药保健组合物，其特征在于：所述各原料药按以下述重量份进行配比：乌梅26份、葛根15份、莲子15份、枸杞子10份、黑芝麻10份、大豆低聚糖6份、魔芋精粉6份、左旋肉碱6份、大豆分离蛋白6份。
4.如权利要求1所述一种用于减脂降糖的中药保健组合物，其特征在于：所述内服制剂为茶剂、颗粒剂、软胶囊剂。
5.如权利要求1所述一种用于减脂降糖的中药保健组合物，其特征在于：所述食品制剂为代餐饼干、代餐粉、茶剂。
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