CN108283314A - One kind containing L-Glutamine and three branched-chain amino acid compound health products and preparation method thereof - Google Patents
One kind containing L-Glutamine and three branched-chain amino acid compound health products and preparation method thereof Download PDFInfo
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- CN108283314A CN108283314A CN201711289821.1A CN201711289821A CN108283314A CN 108283314 A CN108283314 A CN 108283314A CN 201711289821 A CN201711289821 A CN 201711289821A CN 108283314 A CN108283314 A CN 108283314A
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- 238000002360 preparation method Methods 0.000 title claims abstract description 22
- 230000036541 health Effects 0.000 title claims abstract description 13
- -1 branched-chain amino acid compound Chemical class 0.000 title claims abstract description 11
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 title claims description 30
- 229930182816 L-glutamine Natural products 0.000 title claims description 27
- 239000000843 powder Substances 0.000 claims abstract description 38
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims abstract description 30
- 238000003756 stirring Methods 0.000 claims abstract description 30
- 239000000126 substance Substances 0.000 claims abstract description 30
- 238000002156 mixing Methods 0.000 claims abstract description 16
- 102100030840 AT-rich interactive domain-containing protein 4B Human genes 0.000 claims abstract description 15
- 101000792935 Homo sapiens AT-rich interactive domain-containing protein 4B Proteins 0.000 claims abstract description 15
- 239000000463 material Substances 0.000 claims abstract description 14
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- 239000004375 Dextrin Substances 0.000 claims abstract description 10
- 229930091371 Fructose Natural products 0.000 claims abstract description 10
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims abstract description 10
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- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims abstract description 10
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- 229930182844 L-isoleucine Natural products 0.000 claims 1
- 229960000310 isoleucine Drugs 0.000 claims 1
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 abstract description 5
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
Present specification belongs to health-related field of food, discloses a kind of preparation method of glutamine containing L and three branched-chain amino acid compound health products comprising following steps：1) L glutamine, BCAA, fructose, grape juice, medlar powder, kudzu-vine root powder, tangerine peel powder and Vc are taken, is placed in the first mixer, mixes well, obtains first group of substance；2) citric acid, sodium citrate and food flavor are taken, is placed in the second mixer, mixes well, obtains second group of substance；3) it by first group of substance and second group of material mixing, stirs evenly, then adds sterile water, be heated to 40 50 DEG C while stirring, then dextrin is added, continues to stir 30 60min under heat-retaining condition, then stand 60min, squeezes sieving, dry 30 60min, whole grain to get.The present invention uses the formula of science, has apparent synergistic effect between each component, has and improve immunity and other effects.
Description
Technical field
The present invention relates to one kind containing L-Glutamine and three branched-chain amino acid compound health products and preparation method thereof, belongs to guarantor
Strong based food field.
Background technology
L-Glutamine (L-Gln) also known as left-handed bran glutamine are that mammal and the indispensable conditionity of human body must
Need amino acid.L-Glutamine is helpful to the rehabilitation of enteritis, stomach ulcer and angioleucitis patient, it may also be used for enhancing is big
Brain function, auxiliary treatment is retarded, muscular dystrophy and alcoholism etc..
In terms of enteron aisle, supplemented with exogenous L-Glutamine can provide the energy for intestinal mucosa cell, increase and be damaged intestines
The blood flow in road promotes the increase of prostaglandin and stomach lining mucous secretion amount, promotes to repair intestinal mucosa cell, keeps viscous
Membrane structure is complete, prevents gut atrophy.L-Glutamine can also maintain the intestinal permeability of patients with severe pancreatitis, prevent intestines
Transposition occurs for road bacterium, inhibits release inflammatory mediator, the stress reaction of body is made to mitigate, promote patients ' recovery.
In terms of liver protecting, L-Glutamine can be that liver synthesizes oxidation-reduction resistance substance glutathione (GSH)
Pidolidone is provided, if L-Glutamine shortage cannot play the role of being effectively protected to liver function.L-Glutamine may be used also
To promote lipid material in liver to decompose, effectively prevents fatty liver and generate.
In terms of immune response, L-Glutamine can generate reduced-NADP H in metabolic process, so as to promote
Various immune cell propagations and secretion are lymphocytes by the necessary material that cell Proliferation occurs when antigenic stimulus, L- paddy ammonia
The immunocompetence of body can also weaken when amide is horizontal relatively low.
Three branched-chain amino acids, abbreviation BCAA are L-Leu: l-Isoleucine: three kinds of amino acid of Valine press 2: 1: 1
Ratio mix, BCAA can promote protein anabolism after exercise, accelerate muscle synthesis, reduce musculature
It decomposes, helps to increase muscle.Meanwhile or in vivo skeletal muscle energy supply primary amino acid.
Invention content
It is an object of the invention to overcome current technical defect, to solve current market sales of compound amino acid
The shortcomings of electuary dissolving is slow, poor taste, both effectiveness unobvious provides and a kind of containing L-Glutamine and the compound guarantor of three branched-chain amino acids
Strong product and preparation method thereof.
The present invention is achieved by the following technical solution：
A kind of preparation method containing L-Glutamine and three branched-chain amino acid compound health products comprising following steps：
1) L-Glutamine, BCAA, fructose, grape juice, medlar powder, kudzu-vine root powder, tangerine peel powder and Vc are taken, is placed in first
It in mixer, mixes well, obtains first group of substance；
2) citric acid, sodium citrate and food flavor are taken, is placed in the second mixer, mixes well, obtains second group
Substance；
3) it by first group of substance and second group of material mixing, stirs evenly, then adds sterile water, be heated to while stirring
40-50 DEG C, dextrin is then added, continues to stir 30-60min under heat-retaining condition, then stand 60min, squeezes sieving, dry 30-
60min, whole grain to get.
Further,
The preparation method includes the following steps：
1) by L-Glutamine 25-35kg, BCAA 15-25kg, fructose 10-20kg, grape juice 10-15kg, medlar powder
5-10kg, kudzu-vine root powder 2-5kg, tangerine peel powder 2-5kg, Vc 2-5kg, are placed in the first mixer, mix well, obtain first group
Substance；
2) citric acid 0.05-0.1kg, sodium citrate 0.05-0.15kg, food flavor 0.01-0.03kg are placed in second
It in mixer, mixes well, obtains second group of substance；
3) it by first group of substance and second group of material mixing, stirs evenly, is then settled to 100L, side stirring with sterile water
While being heated to 40-50 DEG C, 6-7kg dextrin is then added, continues to stir 30-60min under heat-retaining condition, then stand 60min, squeeze
Cross 20-30 mesh sieve, 60 DEG C of dry 30-60min, whole grain to get.
Further,
The preparation method includes the following steps：
1) by L-Glutamine 25kg, BCAA 20kg, fructose 15kg, grape juice 10kg, medlar powder 10kg, kudzu-vine root powder
2kg, tangerine peel powder 2kg, Vc 2kg, is placed in the first mixer, mixes well, and obtains first group of substance；
2) citric acid 0.05kg, sodium citrate 0.1kg, food flavor 0.01kg are placed in the second mixer, it is fully mixed
It is even, obtain second group of substance；
3) it by first group of substance and second group of material mixing, stirs evenly, is then settled to 100L, side stirring with sterile water
While being heated to 40 DEG C, 6kg dextrin is then added, continues to stir 30min under heat-retaining condition, then stand 60min, squeezed 30 mesh
Sieve, 60 DEG C of dry 30min, whole grain to get.
Further,
The BCAA is by L-Leu: l-Isoleucine: Valine is obtained by mixing by 2: 1: 1 mass ratio.
The compound health products prepared according to the above-mentioned preparation method being allowed to described in one are also claimed in the present invention.
Beneficial effects of the present invention are main but are not limited to the following aspects：
The present invention uses the formula of science, has apparent synergistic effect between each component, have rise the strong liver of flesh, refresh oneself it is awake
Brain, raising immunity, holding intestinal health and other effects, meanwhile, excellent taste abundant with taste, edible safety, convenient, guarantor
The matter phase is long, easy to carry, and target user is extensive, effect stability, is suitble to large-scale production；
In preparation process of the present invention, using respectively by more than mass fraction or raw material that mass fraction is few is pre-mixed, so
It is mixed again afterwards, ensures that raw material can be sufficiently mixed uniformly；
The adequate nutrition supply of protein is to maintain the material base of Cellular Immunity and humoral immunity ability, amino acid
It is the base unit for constituting protein, selects that compound amino acid is used to meet nutrition, battalion as ingredient the effect of improving immunity
Support immunology basic theories and application practice, the present invention is arranged in pairs or groups health care food materials by amino acid needed by human, using rationally matching
Side and technique, the product of preparation achieve the effect that enhance immunity, zoopery prompt, each raw material collaboration in product of the present invention
Effect is good, can significantly improve mouse lymphocyte proliferation.
Specific implementation mode
In order to make those skilled in the art better understand the technical solutions in the application, having below in conjunction with the application
Body embodiment more clearly and completely describes the present invention, it is clear that described embodiment is only the application one
Divide embodiment, instead of all the embodiments.Based on the embodiment in the application, those of ordinary skill in the art are not making
The every other embodiment obtained under the premise of creative work, should all belong to the scope of protection of the invention.
Experimental method used in following embodiments is conventional method unless otherwise specified.
Raw material used in following embodiments, is commercially available unless otherwise specified.
Embodiment 1
A kind of preparation method containing L-Glutamine and three branched-chain amino acid compound health products comprising following steps：
By L-Glutamine 25kg, and BCAA (three branched-chain amino acids, by L-Leu: l-Isoleucine: Valine presses 2:
1: 1 mass ratio is obtained by mixing) 20kg, fructose 15kg, grape juice 10kg, medlar powder 10kg, kudzu-vine root powder 2kg, tangerine peel powder
2kg, Vc (vitamin C) 2kg, is placed in the first mixer, mixes well, and obtains first group of substance；
Citric acid 0.05kg, sodium citrate 0.1kg, food flavor 0.01kg are placed in the second mixer, it is fully mixed
It is even, obtain second group of substance；
It by first group of substance and second group of material mixing, stirs evenly, is then settled to 100L with sterile water, while stirring
40 DEG C are heated to, 6kg dextrin is then added, continues to stir 30min under heat-retaining condition, then stand 60min, keeps it internal full of more
And close hole, enlarged volume, quality are soft, squeeze sieving (30 mesh), 60 DEG C of dry 30min, whole grain to get.
The amount of application of product of the present invention：Each adult daily 1 time, each 10-20g.
Embodiment 2
A kind of preparation method containing L-Glutamine and three branched-chain amino acid compound health products comprising following steps：
By L-Glutamine 30kg, BCAA 15kg, fructose 10kg, grape juice 10kg, medlar powder 6kg, kudzu-vine root powder 3kg,
Tangerine peel powder 3kg, Vc 3kg, is placed in the first mixer, mixes well, and obtains first group of substance；
Citric acid 0.1kg, sodium citrate 0.1kg, food flavor 0.02kg are placed in the second mixer, are mixed well,
Obtain second group of substance；
It by first group of substance and second group of material mixing, stirs evenly, is then settled to 100L with sterile water, while stirring
37 DEG C are heated to, 7kg dextrin is then added, continues to stir 40min under heat-retaining condition, then stand 60min, keeps it internal full of more
And close hole, enlarged volume, quality are soft, squeeze sieving (20 mesh), 60 DEG C of dry 30min, whole grain to get.
The amount of application of product of the present invention：Each adult daily 1 time, each 10-20g.
Embodiment 3
A kind of preparation method containing L-Glutamine and three branched-chain amino acid compound health products comprising following steps：
By L-Glutamine 28kg, BCAA 18kg, fructose 12kg, grape juice 12kg, medlar powder 8kg, kudzu-vine root powder 3kg,
Tangerine peel powder 2kg, Vc 2kg, is placed in the first mixer, mixes well, and obtains first group of substance；
Citric acid 0.05kg, sodium citrate 0.15kg, food flavor 0.01kg are placed in the second mixer, it is fully mixed
It is even, obtain second group of substance；
It by first group of substance and second group of material mixing, stirs evenly, is then settled to 100L with sterile water, while stirring
38 DEG C are heated to, 6.5kg dextrin is then added, continues to stir 50min under heat-retaining condition, then stand 60min, makes to be full of inside it
More and close holes, enlarged volume, quality is soft, squeeze sieving (30 mesh), 60 DEG C of dry 30min, whole grain to get.
The amount of application of product of the present invention：Each adult daily 1 time, each 10-20g.
Embodiment 4
The performance measurement of product prepared by 1-3 of the embodiment of the present invention：
After testing, the obtained product particle of the present invention is uniform in size, and color and luster is consistent, is in uniform color and luster after dissolving gelatinization.This hair
It is bright also to have detected dissolution time, it imposes a condition under conditions of water temperature is 30 DEG C, 120rpm is stirred, to be arranged in 500ml water and adding
Add 10g, is compared with Instant branched-chain amino acid, as shown in table 1 below.
Table 1
Conclusion：As shown in table 1, compared with Instant branched-chain amino acid, product dissolving prepared by 1-3 of the embodiment of the present invention is fast
Degree is higher, and turbidity is low, is in uniform color and luster after dissolving gelatinization, market application prospect is wide.
Embodiment 5
Influence of the product of the present invention to mouse lymphocyte：
Trial product to be measured：Embodiment 1；Reference examples 1：Glutamine is not added, the amount of glutamine uses BCAA polishings,
Remaining same embodiment 1；Reference examples 2：Do not add grape juice and medlar powder, the amount of grape juice and medlar powder is mended using kudzu-vine root powder
Together, remaining is the same as embodiment 1；Reference examples 3：Do not add kudzu-vine root powder and tangerine peel powder, the amount of kudzu-vine root powder and tangerine peel powder uses medlar powder
Polishing, remaining is the same as embodiment 1.
Experiment process：Kunming kind female mice, weight 18g-22g.Each group takes 30 mouse, is divided into 5 groups, respectively
1 group of embodiment, reference examples 1-3 groups, blank control group.Edible daily primary, each dosage is 10mg, and blank control group eats phase
The physiological saline of homogenous quantities, it is continuous two weeks edible.
It is sterile to take spleen, cell suspension, living cell counting number is made, adjustment cell concentration is 5 × 106A/mL, cell is hanged
During liquid divides holes to be added, per hole 1mL, a hole adds 75 μ L of ConA liquid wherein, and 5% carbon dioxide as a contrast, is set in another hole, and 37
DEG C culture 72h.Culture terminates preceding 4h, and supernatant 0.7mL is gently sucked per hole, and 0.7mL is added and is free of calf serum
RPMI1640 culture solutions, while the holes MTT50uL/ are added, continue to cultivate 4h.After culture, 1mL acid isopropyls are added per hole
Alcohol blows and beats mixing, purple crystal is made to be completely dissolved.Then it is dispensed into 96 well culture plates, 3 parallel holes are made in each hole, use enzyme
Instrument is marked, the OD value at 570nm wavelength is surveyed.The proliferative capacity of lymphocyte with plus the OD value in the holes ConA subtract and be not added with
The OD value in the holes ConA indicates.
Same procedure has detected influence of the high dose group (dosage 50mg) to lymphopoiesis ability.
Influence of each group product to mouse lymphocyte proliferative capacity is as shown in table 2.
Table 2
Conclusion：As shown in Table 2, compared with blank control group, 1 group of embodiment and control group 1-3 groups can improve lymph
The effect of stimulation of ability of cell proliferation, embodiment 1 is better than control group 1-3, and each raw material in embodiment 1 is prompted to have preferable collaboration
Effect, and the effect of high dose group is better than low dose group.
Listed above is only the best specific embodiment of the present invention.It is clear that the invention is not restricted to which above example, may be used also
With there are many deformations.All changes that those skilled in the art directly can export or associate from present disclosure
Shape is considered as protection scope of the present invention.
Claims (5)
1. a kind of preparation method containing L-Glutamine and three branched-chain amino acid compound health products comprising following steps：
1) L-Glutamine, BCAA, fructose, grape juice, medlar powder, kudzu-vine root powder, tangerine peel powder and Vc are taken, the first mixing is placed in
It in device, mixes well, obtains first group of substance；
2) citric acid, sodium citrate and food flavor are taken, is placed in the second mixer, mixes well, obtains second group of substance；
3) it by first group of substance and second group of material mixing, stirs evenly, then adds sterile water, be heated to 40-50 while stirring
DEG C, dextrin is then added, continues to stir 30-60min under heat-retaining condition, then stand 60min, squeezes and be sieved, dry 30-60min,
Whole grain to get.
2. preparation method according to claim 1, which is characterized in that the preparation method includes the following steps：
1) by L-Glutamine 25-35kg, BCAA 15-25kg, fructose 10-20kg, grape juice 10-15kg, medlar powder 5-
10kg, kudzu-vine root powder 2-5kg, tangerine peel powder 2-5kg, Vc 2-5kg, are placed in the first mixer, mix well, and obtain first group of object
Matter；
2) citric acid 0.05-0.1kg, sodium citrate 0.05-0.15kg, food flavor 0.01-0.03kg are placed in the second mixing
It in device, mixes well, obtains second group of substance；
3) it by first group of substance and second group of material mixing, stirs evenly, is then settled to 100L with sterile water, add while stirring
Then 6-7kg dextrin is added to 40-50 DEG C in heat, continue to stir 30-60min under heat-retaining condition, then stand 60min, squeeze
20-30 mesh sieve, 60 DEG C of dry 30-60min, whole grain to get.
3. preparation method according to claim 2, which is characterized in that the preparation method includes the following steps：
1) by L-Glutamine 25kg, BCAA 20kg, fructose 15kg, grape juice 10kg, medlar powder 10kg, kudzu-vine root powder 2kg,
Tangerine peel powder 2kg, Vc 2kg, is placed in the first mixer, mixes well, and obtains first group of substance；
2) citric acid 0.05kg, sodium citrate 0.1kg, food flavor 0.01kg are placed in the second mixer, are mixed well,
Obtain second group of substance；
3) it by first group of substance and second group of material mixing, stirs evenly, is then settled to 100L with sterile water, add while stirring
Then 6kg dextrin is added to 40 DEG C in heat, continue to stir 30min under heat-retaining condition, then stand 60min, squeezed 30 mesh and sieves, and 60
DEG C dry 30min, whole grain to get.
4. according to the preparation method described in claim 1-3, which is characterized in that the BCAA is by L-Leu：L-Isoleucine：
Valine is obtained by mixing by 2: 1: 1 mass ratio.
5. being allowed to the compound health products of the preparation of the preparation method described in one according to claim 1-4.
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