CN103734716A - Branched chain amino acid - Google Patents

Branched chain amino acid Download PDF

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Publication number
CN103734716A
CN103734716A CN201310693215.1A CN201310693215A CN103734716A CN 103734716 A CN103734716 A CN 103734716A CN 201310693215 A CN201310693215 A CN 201310693215A CN 103734716 A CN103734716 A CN 103734716A
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China
Prior art keywords
amino acid
chain amino
branched chain
valine
leucine
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CN201310693215.1A
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Chinese (zh)
Inventor
徐凤鸣
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WUXI JINWEIAN BIOLOGICAL SCIENCE & TECHNOLOGY Co Ltd
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WUXI JINWEIAN BIOLOGICAL SCIENCE & TECHNOLOGY Co Ltd
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Priority to CN201310693215.1A priority Critical patent/CN103734716A/en
Publication of CN103734716A publication Critical patent/CN103734716A/en
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/175Amino acids
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Abstract

The invention discloses a branched chain amino acid. The branched chain amino acid is prepared from the components: leucine, isoleucine and valine, wherein the mass ratio of the leucine, the isoleucine to the valine is 48.5 percent: 24.92 percent: 26.6 percent. With the adoption of the branched chain amino acid, as the actual additive amount is regulated according to the actual conditions of China raw material market, ideal gold proportion is achieved, and the branched chain amino acid BCAA which has the effects of strengthening body health and prolonging the life achieves the optimal health-care effect.

Description

A kind of branched-chain amino acid
Technical field
The present invention relates to a kind of branched-chain amino acid.
Background technology
Scientist has found a kind of medicine that can promote longevity, and small white mouse, has tested with it, succeeds first.The medicine of this mystery is exactly the mixture being comprised of this 3 seed amino acid of leucine, isoleucine and valine, formal name used at school " branched-chain amino acid ".
Branched-chain amino acid (BCAA:Branched Chain Amino Acids) refers to a group amino acid that contains side chain in structure, has comprised leucine, isoleucine, valine.This three seed amino acid belongs to essential amino acid, has inseparable relation with synthetic protein, need not pass through body metabolism, just can directly provide energy to use to human body.In human body, approximately 33% muscle protein is to be become by BCAA Group, accounts for essential amino acid approximately 35% left and right.
The motion (for example: heavily instruction, extreme sport, body-building) of middle intensity can cause the content fast-descending of BCAA to cause the concentration of catabolism, fatigue and the Testosterone (stosterone) of muscle to decline.BCAA is the pith of muscle protein, and when the BCAA in blood of human body is inadequate, the BCCA that just can decompose in muscle makes the energy, produce power, carbon dioxide and water.During training, in skeletal muscle, the consumption of BCAA is very fast, supplements branched-chain amino acid and can improve locomitivity, delay fatigue, the reparation muscle because of motion loss before motion or in motion.After motion, with canteen, with BCAA, contribute to other amino acid whose absorption at once or after motion.
The main function of BCAA has: recover health moisture and electrolyte, recover glycogen deposit rapidly, strengthen muscular endurance, rebuild intramuscular protein.Generally speaking, the function of BCAA is the synthetic and metabolism for promoting rest period protein, except accelerating the synthetic decomposition that can also reduce musculature of muscle, and BCAA has good anti-decomposability, can be used for preventing the loss of muscle and protein, can also stimulate insulin, promote muscle to other amino acid whose absorptions simultaneously.
In brief, the function of BCAA is as follows:
1. promote muscular endurance growth;
2. recover the muscular strength running off after motion;
3. safeguard muscle cell and protection musculature;
4. prevent that muscle runs off;
5. life-extending.
Owing to existing the relation of competition each other between BCAA when absorbing, therefore must supplement with Time, just can guarantee best assimilation effect.
In nutrition science, three kinds of main components of BCAA: leucine, isoleucine, valine, owing to existing the relation of competition each other when absorbing, just can be guaranteed best effect so must supplement simultaneously.According to conventional formulation, BCAA is take 2:1:1 as optimum formula always, is known as " gold proportioning ".As long as generally acknowledge and reach " gold proportioning ", just can play the most perfectly nutritive validity.
The current main manufacturer of domestic branched-chain amino acid is Yichang Sanxia Pharmaceutical Co., Ltd., Shandong Fu Feng fermentation group, the biological group of Shandong Lu Zhou etc., due to technological reason, these producers are mainly used Studies on Fermentation of L-isoleucine, Valine, all with fermentation method, do not produce leucine, so mainly still extract from human hair, drake feather, pig hair in domestic leucine source.Immature due to extraction process, domestic all production ILEs and Valine factory can only produce the product of USP24 rank, its purity detects and can only reach 93%-95% with HPLC, and the use of leucine manufacturer is Hydrolyze method, extraction process is used the precipitation method, comparative maturity on separation-extraction technology, its leucine detects effective purity more than 99% with HPLC, so three seed amino acids in theory the gold proportioning of 2:1:1 be really to reach perfect combination.
Because current branched-amino acid starting material mainly comes from China, because the production status of current Chinese branched-chain amino acid, American-European countries all reaches " gold proportioning " on theory significance by adjusting these three amino acid whose proportionings.
Summary of the invention
The technical problem to be solved in the present invention is the defect that overcomes prior art, and a kind of branched-chain amino acid is provided, and this branched-chain amino acid is real has reached " gold proportioning ".
In order to solve the problems of the technologies described above, the invention provides following technical scheme:
A kind of branched-chain amino acid of the present invention, comprises leucine, isoleucine and valine, and the mass ratio of described leucine, isoleucine and valine is leucine: isoleucine: valine=48.45%:24.92%:26.63%.
Branched-chain amino acid provided by the invention, according to the actual conditions of Chinese raw materials market, has adjusted actual addition, has reached desirable " gold proportioning ", allows the branched-chain amino acid BCAA that improves the health, promotes longevity reach top health-care effect.
The specific embodiment
Below the preferred embodiments of the present invention are described, should be appreciated that preferred embodiment described herein, only for description and interpretation the present invention, is not intended to limit the present invention.
Current domestic branched-chain amino acid producer is mainly the producer of Studies on Fermentation of L-isoleucine (L-ISOLEUCINE) and Valine (L-VALINE) and the producer that Hydrolyze method is extracted L-Leu (L-LEUCINE) from human hair, drake feather, pig hair.Due in fermentation production process, while being accompanied by the growth of ILE and Valine strain fermentation, other amino acid also, simultaneously in growth, adds the immature of purifying technique, and it is desirable more than 99% that the HPLC purity of ILE and Valine reaches far away.High efficiency liquid phase (HPLC) the detection level data of these three product domestic raw material are as follows at present:
Figure BDA0000438767830000031
So according to the proportioning of theoretic 2:1:1, actual mixed L-Leu, ILE, the content of Valine is:
Figure BDA0000438767830000032
Visible, so-called BCAA scientific matching cannot really reach the ideal effect of " gold proportioning " in fact in the market;
The present invention, according to the actual conditions of Chinese raw materials market, has adjusted actual addition, has reached desirable " gold proportioning ", allows the branched-chain amino acid BCAA that improves the health, promotes longevity reach top health-care effect:
Figure BDA0000438767830000041
Visible, branched-chain amino acid provided by the invention, real having reached " gold proportioning ", can better reach the effect of nutrition.
Finally it should be noted that: the foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, although the present invention is had been described in detail with reference to previous embodiment, for a person skilled in the art, its technical scheme that still can record aforementioned each embodiment is modified, or part technical characterictic is wherein equal to replacement.Within the spirit and principles in the present invention all, any modification of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.

Claims (1)

1. a branched-chain amino acid, comprises leucine, isoleucine and valine, it is characterized in that, the mass ratio of described leucine, isoleucine and valine is leucine: isoleucine: valine=48.45%:24.92%:26.63%.
CN201310693215.1A 2013-12-16 2013-12-16 Branched chain amino acid Pending CN103734716A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201310693215.1A CN103734716A (en) 2013-12-16 2013-12-16 Branched chain amino acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201310693215.1A CN103734716A (en) 2013-12-16 2013-12-16 Branched chain amino acid

Publications (1)

Publication Number Publication Date
CN103734716A true CN103734716A (en) 2014-04-23

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Country Status (1)

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CN (1) CN103734716A (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104757563A (en) * 2015-04-24 2015-07-08 刘尚文 Weight-losing health food and preparation method thereof
CN105214094A (en) * 2015-10-27 2016-01-06 无锡金维氨生物科技有限公司 The branched-chain amino acid powder that a kind of bulk density improves
CN105249127A (en) * 2015-10-27 2016-01-20 无锡金维氨生物科技有限公司 Flavor type instant branched chain amino acid solid beverage
CN105288638A (en) * 2015-10-27 2016-02-03 无锡金维氨生物科技有限公司 Method for improving bulk density of branched chain amino acid powder
CN105614441A (en) * 2014-12-01 2016-06-01 无锡金维氨生物科技有限公司 Instant branched-chain amino acid SBCAA
CN107708659A (en) * 2015-12-14 2018-02-16 有限会社Ant It is compounded with the face skin preparations for extenal use of amino acid
CN107997183A (en) * 2017-12-25 2018-05-08 大连医诺生物股份有限公司 Microencapsulation is sustained branched-chain amino acid
CN108283314A (en) * 2017-11-30 2018-07-17 新疆阜丰生物科技有限公司 One kind containing L-Glutamine and three branched-chain amino acid compound health products and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1625346A (en) * 2002-02-22 2005-06-08 味之素株式会社 Powder of amino acids and method for producing the same
CN102149374A (en) * 2008-09-09 2011-08-10 味之素株式会社 Orally administrable formulation containing branched chain amino acid
CN102458417A (en) * 2009-06-24 2012-05-16 味之素株式会社 Enhancer of activity of nucleic acid analogue
CN103070330A (en) * 2011-10-25 2013-05-01 北京康比特体育科技股份有限公司 Anti-fatigue nutritional bar and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1625346A (en) * 2002-02-22 2005-06-08 味之素株式会社 Powder of amino acids and method for producing the same
CN102149374A (en) * 2008-09-09 2011-08-10 味之素株式会社 Orally administrable formulation containing branched chain amino acid
CN102458417A (en) * 2009-06-24 2012-05-16 味之素株式会社 Enhancer of activity of nucleic acid analogue
CN103070330A (en) * 2011-10-25 2013-05-01 北京康比特体育科技股份有限公司 Anti-fatigue nutritional bar and preparation method thereof

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105614441A (en) * 2014-12-01 2016-06-01 无锡金维氨生物科技有限公司 Instant branched-chain amino acid SBCAA
CN104757563A (en) * 2015-04-24 2015-07-08 刘尚文 Weight-losing health food and preparation method thereof
CN105214094A (en) * 2015-10-27 2016-01-06 无锡金维氨生物科技有限公司 The branched-chain amino acid powder that a kind of bulk density improves
CN105249127A (en) * 2015-10-27 2016-01-20 无锡金维氨生物科技有限公司 Flavor type instant branched chain amino acid solid beverage
CN105288638A (en) * 2015-10-27 2016-02-03 无锡金维氨生物科技有限公司 Method for improving bulk density of branched chain amino acid powder
CN105249127B (en) * 2015-10-27 2017-11-17 江苏金维氨生物工程有限公司 A kind of instant branched-chain amino acid solid beverage of flavor type
CN105214094B (en) * 2015-10-27 2017-11-21 江苏金维氨生物工程有限公司 The branched-chain amino acid pulvis that a kind of bulk density improves
CN107708659A (en) * 2015-12-14 2018-02-16 有限会社Ant It is compounded with the face skin preparations for extenal use of amino acid
CN107708659B (en) * 2015-12-14 2020-07-03 有限会社Ant External preparation for facial skin containing amino acids
CN108283314A (en) * 2017-11-30 2018-07-17 新疆阜丰生物科技有限公司 One kind containing L-Glutamine and three branched-chain amino acid compound health products and preparation method thereof
CN107997183A (en) * 2017-12-25 2018-05-08 大连医诺生物股份有限公司 Microencapsulation is sustained branched-chain amino acid
CN107997183B (en) * 2017-12-25 2021-10-22 大连医诺生物股份有限公司 Microencapsulated sustained-release branched-chain amino acids

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Application publication date: 20140423