CN108265001A - Collector - Google Patents
Collector Download PDFInfo
- Publication number
- CN108265001A CN108265001A CN201710004445.0A CN201710004445A CN108265001A CN 108265001 A CN108265001 A CN 108265001A CN 201710004445 A CN201710004445 A CN 201710004445A CN 108265001 A CN108265001 A CN 108265001A
- Authority
- CN
- China
- Prior art keywords
- tube body
- filter plate
- leading
- edge
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
Abstract
The present invention relates to field of biomedicine technology, provide a kind of collector, and including tube body, axially disposed in the tube body to have filter plate, the receiving space of tube body is divided into first sample storage area and sample extraction area by the filter plate in an axial direction.The beneficial effects of the invention are as follows:The swab for being attached with mouth desquamated cells is put into first sample storage area, the DNA in cell is discharged by the cracking composition preserved in liquid, DNA is by filter plates to sample extraction area, it in this way can be to avoid sampling probe touches buccal swab and sampling probe bending or position is caused deviation occur, on the other hand, when containing sticky sputum or swill in the saliva of collection, it can prevent it from blocking sampling probe by filter plates, this operation is without sputum that swab is taken out or liquefied, it is easy to operate, save the time.
Description
Technical field
The present invention relates to field of biomedicine technology, more specifically to a kind of collector.
Background technology
Human saliva is a kind of mixture of complexity, not only containing mouth desquamated cells also containing various protein, research
It was found that the various protein components in blood are also existed in saliva, saliva can reflect various protein levels in blood
Variation.Due to obtaining mouth desquamated cells or saliva without wound, it is convenient to collect, and is therefore widely used in plurality of medical inspection
It surveys, such as gene sequencing detection.In addition the prior art can also use buccal swab acquisition human oral cavity to stick when collecting saliva
Film comes off newer cell DNA sample.In order to facilitate carrying and preserving, detection sample is collected usually using collector, it is existing
In technology, collector includes acquisition portion and tube body, then will generally be managed in swab or saliva collection to tube body by acquisition portion
Body placement platform is extracted again, and extraction equipment such as liquid-transfering needle is damaged in order to prevent, is needed first by the swab of storage from pipe
Body taking-up could carry out, and operation is more complicated, especially when being operated to a large amount of collector, wastes time and reduces extraction
Efficiency.Therefore a kind of convenience sample is needed to collect and extract again, collector easy to operate.
Invention content
It collects and extracts again, collector easy to operate the purpose of the present invention is to provide a kind of convenience sample.
A kind of collector, including tube body, axially disposed in the tube body to have filter plate, the filter plate is empty by the receiving of tube body
Between be divided into first sample storage area and sample extraction area in an axial direction.
Preferably, the collector further includes connecting portion and collects head, and the connecting portion is connected with tube body and positioned at pipe
Above body, the collection head includes pan and leading-out portion, and the leading-out portion is located at the lower section of pan and is connected with the osculum of pan
Logical, the leading-out portion is removably fixedly connected with the connecting portion;
Partition portion is equipped in the leading-out portion, the partition portion includes favouring the guide face of the tube body axis of the leading-out portion.
Preferably, the guide face includes the first edge and second edge that are connected with each other, and the first edge is adjacent to institute
Tube body axis is stated, second edge connects the inner wall of the leading-out portion tube body.
Preferably, the outer wall upper edge of the leading-out portion is axially arranged with the first strip bulge, is set on the inner wall of the connecting portion
The first contraposition groove being adapted with first strip bulge is equipped with, first strip bulge is contained in first contraposition
So that the hanging of the first edge in the partition portion and the filter plate in groove.
Preferably, the leading-out portion outer surface is equipped with the first external screw thread, and the connecting portion inner surface is equipped with and described first
The first internal thread that external screw thread is adapted, the first edge in the partition portion and the filter plate can be made by tightening leading-out portion and connecting portion
Hanging.
Preferably, the first edge in the partition portion and the top of the filter plate are elastic material.
Preferably, the filter plate and tube body integrated injection molding.
Preferably, the inboard wall of tube body it is axially disposed there are two with the filter plate at left and right sides of be adapted second contraposition
Groove, after the filter plate is inserted into tube body, the filter plate both sides are located in the described second contraposition groove.
Preferably, the collector further includes cover, and the cover is used for sealed tube body.
Preferably, the inner wall upper edge of the cover is axially arranged with multiple third strip bulges, on the outer wall of the connecting portion
It is equipped with multiple third contraposition grooves being adapted with third strip bulge in an axial direction, the third strip bulge is contained in described
Tube body can be sealed in third contraposition groove.
Preferably, the cover includes head and neck, and the exterior is equipped with and the first internal thread in connecting portion
The second external screw thread being adapted, tube body can be sealed by tightening cover.
Preferably, the collector further includes pedestal, is provided on the outer wall in the first sample storage area/sample extraction area convex
Go out portion, the 4th contraposition groove being adapted with the protrusion, the protrusion and the 4th contraposition groove are equipped in the pedestal
For positioning the first sample storage area/placement position of the sample extraction area in pedestal.
Relative to the prior art, the receiving space of tube body is divided into first sample using filter plate and deposited by collector of the invention in an axial direction
Area and sample extraction area are put, the swab for being attached with mouth desquamated cells is put into or directly ptysis is to sample holding region, sample
Product by filter plates to sample holding region, in this way from sample extraction area extraction sample can touch swab to avoid sampling probe and
Sampling probe bending or position is caused deviation occur;When containing sticky sputum or swill in the saliva of collection, pass through filter
Plate filtering can prevent it from blocking sampling probe;This operation is i.e. extractable without sputum that swab is taken out or liquefied, easy to operate, section
It saves time.In addition, being equipped with partition portion in the leading-out portion for collecting head, when collecting saliva, the partition portion can be initial by saliva
Sample is guided to the first sample storage area of tube body, so as to prevent saliva from entering sample extraction area.The first edge and filter plate in partition portion
Top be elastic material, so as to which the top for making the first edge in partition portion and filter plate is combined closely, prevent saliva from collection
When entering tube body leakage occurs for head.The first contraposition groove that the first strip bulge on leading-out portion outer wall is contained in connecting portion is real
It is now fixedly connected or is connected through a screw thread, can quickly realize partition portion first edge and filter plate hanging, easy to operate, section
It saves time.Filter plate both sides are fixed on by the second contraposition groove in tube body, easy to disassemble, it can be achieved that the multifunctional usage of tube body.
The protruding portion of the outer wall in first sample storage area/sample extraction area is inserted into the 4th contraposition groove and collector is fixed in pedestal,
First sample storage area/sample extraction area can be quickly distinguished, when collecting saliva with a large amount of collector, all pedestals are pressed into unification side
To fixed placement, to keep fixed collector horizontal direction position on all pedestals identical simultaneously, it is easy to accomplish mechanization
Operation.
Description of the drawings
Fig. 1 is the cross-sectional view of collector in first embodiment of the invention.
Fig. 2 is the configuration schematic diagram of collector in second embodiment of the invention.
Fig. 3 is the amplification dimensional structure diagram of the collection head of collector shown in Fig. 2.
Fig. 4 is the cross-sectional view of collector in second embodiment of the invention.
Fig. 5 is the configuration schematic diagram of collector in a specific embodiment of the invention.
Fig. 6 is the configuration schematic diagram of collector in another specific embodiment of the present invention.
Fig. 7 is the enlarged structure schematic diagram of regional area A in Fig. 6.
Fig. 8 is the dimensional structure diagram of collector in a specific embodiment of the invention.
Fig. 9 is the configuration schematic diagram of collector and cover in third embodiment of the invention.
Figure 10 is the enlarged structure schematic diagram of regional area B in Fig. 9.
Figure 11 is the configuration schematic diagram of collector in an alternate embodiment of the invention.
Figure 12 is the cross-sectional view of collector and pedestal in fourth embodiment of the invention.
Specific embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to the accompanying drawings and embodiments, it is right
The present invention is further elaborated.
The present invention proposes first embodiment, as shown in Figure 1, the collector includes tube body 101, in tube body 101 in an axial direction
Filter plate 1011 is provided with, the receiving space of tube body 101 is divided into first sample storage area 1012 and sample extraction by filter plate 1011 in an axial direction
Area 1013.In the present embodiment, the width of the filter plate 1011 is substantially identical with the internal diameter of tube body 101, length and the height of tube body 101
It spends identical.Liquid is preserved in use, being packed into first in the tube body 101, then will be attached with the swabs 60 of mouth desquamated cells along A side
To first sample storage area 1012 is put into, the DNA in cell is discharged by the cracking composition preserved in liquid, DNA passes through 1011 mistake of filter plate
It filters to sample extraction area 1013.When being extracted again to sample in tube body 101, first tube body 101 is positioned in extraction platform, so
Control sampling probe is inserted into sample extraction area 1013 along B directions and extracts sample afterwards, can touch swab to avoid sampling probe in this way and
Cause sampling probe be bent or position there is deviation, on the other hand, when in the saliva of collection contain sticky sputum or swill
When, it can prevent it from blocking sampling probe by the filtering of filter plate 1011, this operates the sputum that need not swab 60 be taken out or be liquefied, operation
It is convenient, save the time.
Further, second embodiment is proposed on the basis of first embodiment, as shown in Figure 2, Figure 3 and Figure 4, the present invention
Second embodiment and first embodiment the difference lies in:Collector further includes connecting portion 102 and collects head 20.The connection
Portion 102 is connected with tube body 101 and positioned at 101 top of tube body;The collection head 20 includes pan 201 and leading-out portion 202, export
Portion 202 is located at the lower section of pan 201 and is connected with the osculum of pan 201, and leading-out portion 202 is removably solid with connecting portion 102
Fixed connection.Partition portion 2021 is equipped in leading-out portion 202, the partition portion 2021 includes a guide face 20210, guide face 20210
First edge 20211 and second edge 20212 including interconnection, axis and position of the first edge 20211 adjacent to tube body 101
In in the plane where the outlet of leading-out portion 202, second edge 20212 connects the inboard wall of tube body of leading-out portion 202.Present embodiment
In, first edge 20211 is straight edge, and second edge 20212 is arc edge.Above structure causes leading for the partition portion 2021
Stream interface 20210 favours the axis of 202 tube body of leading-out portion, and the partition portion 2021 seals the outlet of the tube body of leading-out portion 202
It closes as original half.After installation is complete, the half that the tube body of leading-out portion 202 is unclosed exports face first sample storage area
1012, and the first edge 20211 in partition portion 2021 and the hanging of filter plate 1011.The ptysis directly into collection head 20,
Sample by collect first 20 pan 201 collect after, under the water conservancy diversion in partition portion 2021 enter first sample storage area 1012, in this way may be used
Initial sample is avoided to enter sample extraction area 1013, when extracting saliva, removes and collects head 20, with sampling probe from sample extraction area
1013 extraction salivas.
In the present embodiment, the top of first edge 20211 and filter plate 1011 is elastic material, when leading-out portion 202 is with connecting
When socket part 102 is fixedly connected, the top sealable engagement of first edge 20211 and filter plate 1011 prevents saliva from collection head 20
Into leakage occurs during tube body 101.
Further, in the present embodiment, divide on the first sample storage area 1012 of tube body 101 and the outer wall in sample extraction area 1013
It is not provided with the square groove 1014 for labelling.The side of square groove 1014 is equipped with scale 1015, for observing tube body
The volume of saliva is collected in 101.
In a second embodiment, for the fixed form of leading-out portion 202 and connecting portion 102, it is specific that the present invention proposes one
Embodiment, as shown in figure 5, the outer surface of leading-out portion 202 is equipped with the first external screw thread 2022,102 inner surface of connecting portion is equipped with and institute
State the first internal thread 1022 that the first external screw thread 2022 is adapted, leading-out portion 202 be inserted into connecting portion 102 and is tightened, can make every
The first edge 20211 in disconnected portion 2021 and the hanging of filter plate 1011, the saliva collected at this time enter collection head 20 and are separating
The region being directly entered under the water conservancy diversion in portion 2021 is just first sample storage area 1012.This structure can quickly realize partition portion 2021
The hanging of first edge 20211 and filter plate 1011, it is easy to disassemble, it is easy to operate, save the time.
For the fixed form of leading-out portion 202 and connecting portion 102, the present invention proposes another specific embodiment, such as Fig. 6 and
Shown in Fig. 7, the outer wall upper edge of leading-out portion 202 is axially arranged with first strip bulge 2023, is set on the inner wall of connecting portion 102
There are the first contraposition groove 1023 being adapted with the first strip bulge 2023, the tube length of leading-out portion 202 and company in this structure
The tube length of socket part 102 is roughly the same, and the outer diameter of leading-out portion 202 is substantially equal to the inner diameter of connecting portion 102, will
Leading-out portion 202 is inserted into connecting portion 102, and the first strip bulge 2023 is located in the first contraposition groove 1023, and partition portion 2021
First edge 20211 and filter plate 1011 top contraposition engagement, the saliva collected at this time enter collect head 20 in partition portion
The region being directly entered under 2021 water conservancy diversion is just first sample storage area 1012.This structure can quickly realize the of partition portion 2021
The hanging at one edge 20211 and filter plate 1011, it is easy to disassemble, it is easy to operate, save the time.
For the fixed form of filter plate 1011 and tube body 101, the present invention proposes a specific embodiment, as shown in figure 8, pipe
101 inner wall of body is axially disposed, and there are two the be adapted with 1011 both sides of filter plate second contraposition groove 1013, the width of filter plate 1011
Degree is identical with the internal diameter of tube body 101, and length is identical with the height of tube body 101, after filter plate 1011 is inserted into tube body 101, filter plate
1011 both sides are located in the second contraposition groove 1013, so as to which the receiving space of tube body 101 is divided into first sample storage area in an axial direction
1012 and sample extraction area 1013.When needing with 1011 filtered sample of filter plate, 1011 both sides of filter plate can be inserted into the second contraposition
It is fixed in groove 1013, when not needing to filter plate 1011, filter plate 1011 can be taken out, so as to fulfill the multi-functional use of tube body 101
On the way.
Further, on the basis of second embodiment, the present invention proposes 3rd embodiment, as shown in Figure 9, Figure 10, institute
It states collector and further includes cover 30, the inner wall upper edge of cover 30 is axially arranged with multiple third strip bulges 301, the connecting portion
102 outer wall is equipped with multiple third contraposition grooves 1024 being adapted with third strip bulge 301.After having collected sample, take
Then lower collection head 20 covers the third contraposition groove 1024 that cover 30 makes its third strip bulge 301 be contained in connecting portion 102
It is interior, being sealed for sample can be realized in this way.
For the structure of cover, the present invention proposes an alternate embodiment, and as shown in figure 11, the cover 40 includes head
401 and neck 402, the second external screw thread that the outer surface of neck 402 is equipped with first internal thread 102 is adapted in connecting portion 102
4021, after having collected sample, remove and collect head 20, tube body can be sealed by tightening cover 40.
In order to preferably realize the using effect of collector, on the basis of second embodiment, the present invention proposes that the 4th is real
Example is applied, as shown in figure 12, the collector further includes the pedestal 50 being adapted with 101 bottom of tube body, while in sample extraction area
1013 outer wall bottoms are set there are one protruding portion 502, and pedestal 50 is interior to be equipped with the 4th contraposition groove 501 being adapted with protruding portion 502,
Collector is inserted into pedestal 50, protruding portion 502 is located just in its 4th contraposition groove 501, can quickly distinguish so outer
The side that wall includes protruding portion 502 is sample extraction area 1013, and the side without protruding portion 502 is first sample storage area.With big
When the collector of amount collects sample, all pedestals 50 can be pressed to unified direction fixed placement, to keep all pedestals 50 simultaneously
Upper fixed collector horizontal direction position is identical, it is easy to accomplish mechanized operation.
Beneficial effects of the present invention include:
1st, the receiving space of tube body 101 is divided into first sample storage area 1012 and sample extraction area 1013 by filter plate 1011 in an axial direction, will
The swab 60 for being attached with mouth desquamated cells is put into first sample storage area 1012, is discharged in cell by preserving the cracking composition in liquid
DNA, DNA is filtered by filter plate 1011 to sample extraction area 1013, when being extracted again to the sample in tube body 101, can will
Sampling probe is inserted into sample extraction area 1013 and extracts saliva, in this way can be to avoid sampling probe touches swab and sampling probe is caused to be bent
Or there is deviation in position, on the other hand, when containing sticky sputum or swill in the saliva of collection, passes through filter plate 1011
Filtering can prevent it from blocking sampling probe, this operates the sputum that need not swab 60 be taken out or be liquefied, easy to operate, saves the time;
2nd, it collects in the leading-out portion 202 of head 20 and is equipped with partition portion 2021, when collecting saliva, partition portion 2021 can be by the initial sample of saliva
Product are guided to the first sample storage area 1012 of tube body, can prevent saliva initial sample from entering sample extraction area 1013 in this way;
3rd, the first edge 20211 in partition portion 2021 and the top of filter plate 1011 are elastic material, make the of partition portion 2021
The top of one edge 20211 and filter plate 1011 is tightly engaged into, so as to be leaked when preventing saliva from entering tube body 101 from collection head 20
Liquid;
4th, the first contraposition groove 1023 that the first strip bulge 2023 on 202 outer wall of leading-out portion is inserted into connecting portion 102 is realized
It is fixedly connected or is connected through a screw thread, can quickly realize 1011 top pair of first edge 20211 and filter plate in partition portion 2021
Together, it is easy to disassemble, it is easy to operate, save the time;
5th, 1011 both sides of filter plate are fixed on by the second contraposition groove 1013 in tube body 101, easy to disassemble, it can be achieved that tube body 101
Multifunctional usage;
6th, the protruding portion 502 on 1013 outer wall of sample extraction area is inserted into the 4th contraposition groove 501 so as to which collector be fixed on
In 50, base, side of the outer wall with protruding portion 502 can be quickly distinguished as sample extraction area 1013, with a large amount of collector
When collecting sample, all pedestals 50 are pressed into unified direction fixed placement, to keep fixed collection on all pedestals 50 simultaneously
Device horizontal direction position is identical, it is easy to accomplish mechanized operation.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention
All any modification, equivalent and improvement made within refreshing and principle etc., should all be included in the protection scope of the present invention.
Claims (12)
1. a kind of collector, it is characterised in that:Including tube body, axially disposed in the tube body to have filter plate, the filter plate will manage
The receiving space of body is divided into first sample storage area and sample extraction area in an axial direction.
2. collector according to claim 1, it is characterised in that:Further include connecting portion and collect head, the connecting portion with
Tube body is connected and above tube body, and the collection head includes pan and leading-out portion, and the leading-out portion is located at the lower section of pan
And be connected with the osculum of pan, the leading-out portion is removably fixedly connected with the connecting portion;
Partition portion is equipped in the leading-out portion, the partition portion includes favouring the guide face of the tube body axis of the leading-out portion.
3. collector according to claim 2, it is characterised in that:The guide face include be connected with each other first edge and
Second edge, the first edge connect the inner wall of the leading-out portion tube body adjacent to the tube body axis, second edge.
4. collector according to claim 3, it is characterised in that:The outer wall upper edge of the leading-out portion is axially arranged with first
Shape protrusion, is provided with the first contraposition groove being adapted with first strip bulge on the inner wall of the connecting portion, and described the
One strip bulge is contained in the first contraposition groove so that the first edge in the partition portion and the top pair of the filter plate
Together.
5. collector according to claim 3, it is characterised in that:The leading-out portion outer surface is equipped with the first external screw thread, institute
It states connecting portion inner surface and is equipped with the first internal thread being adapted with first external screw thread, institute can be made by tightening leading-out portion and connecting portion
State the first edge in partition portion and the hanging of the filter plate.
6. collector according to claim 4 or 5, it is characterised in that:The first edge in the partition portion and the filter plate
Top be elastic material.
7. collector according to claim 6, it is characterised in that:The filter plate and tube body integrated injection molding.
8. collector according to claim 6, it is characterised in that:The inboard wall of tube body it is axially disposed there are two with it is described
The second contraposition groove being adapted at left and right sides of filter plate, after the filter plate is inserted into tube body, the filter plate both sides are located at described second
It aligns in groove.
9. collector according to claim 8, it is characterised in that:Cover is further included, the cover is used for sealed tube body.
10. collector according to claim 9, it is characterised in that:The inner wall upper edge of the cover is axially arranged with multiple
Three strip bulges, it is recessed that the outer wall upper edge of the connecting portion is axially arranged with multiple thirds contrapositions being adapted with third strip bulge
The third strip bulge is contained in the third contraposition groove and can seal tube body by slot.
11. collector according to claim 9, it is characterised in that:The cover includes head and neck, outside the neck
Surface is equipped with the second external screw thread being adapted with the first internal thread in connecting portion, and tube body can be sealed by tightening cover.
12. according to the collector described in claim 1 to 11 any one, it is characterised in that:Pedestal is further included, the first sample is deposited
It puts and protrusion is provided on the outer wall in area/sample extraction area, the 4th pair be adapted with the protrusion is equipped in the pedestal
Position groove, the protrusion and the 4th contraposition groove are used to position the first sample storage area/pendulum of the sample extraction area in pedestal
Put position.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201710004445.0A CN108265001A (en) | 2017-01-04 | 2017-01-04 | Collector |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN201710004445.0A CN108265001A (en) | 2017-01-04 | 2017-01-04 | Collector |
Publications (1)
Publication Number | Publication Date |
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CN108265001A true CN108265001A (en) | 2018-07-10 |
Family
ID=62771624
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN201710004445.0A Pending CN108265001A (en) | 2017-01-04 | 2017-01-04 | Collector |
Country Status (1)
Country | Link |
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CN (1) | CN108265001A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111473989A (en) * | 2020-04-22 | 2020-07-31 | 重庆沃康生物科技有限公司 | Sampler for enterovirus in excrement |
CN113832138A (en) * | 2021-08-25 | 2021-12-24 | 苏州新海生物科技股份有限公司 | Biological sample preservation system and application thereof |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111473989A (en) * | 2020-04-22 | 2020-07-31 | 重庆沃康生物科技有限公司 | Sampler for enterovirus in excrement |
CN113832138A (en) * | 2021-08-25 | 2021-12-24 | 苏州新海生物科技股份有限公司 | Biological sample preservation system and application thereof |
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