CN108245442A - 一种适用于湿疹皮肤的修复霜 - Google Patents
一种适用于湿疹皮肤的修复霜 Download PDFInfo
- Publication number
- CN108245442A CN108245442A CN201810111952.9A CN201810111952A CN108245442A CN 108245442 A CN108245442 A CN 108245442A CN 201810111952 A CN201810111952 A CN 201810111952A CN 108245442 A CN108245442 A CN 108245442A
- Authority
- CN
- China
- Prior art keywords
- extract
- repair cream
- eczema skin
- repair
- oil
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000006071 cream Substances 0.000 title claims abstract description 39
- 230000008439 repair process Effects 0.000 title claims abstract description 39
- 201000004624 Dermatitis Diseases 0.000 title claims abstract description 31
- 208000010668 atopic eczema Diseases 0.000 title claims abstract description 30
- 239000004909 Moisturizer Substances 0.000 claims abstract description 14
- 239000003995 emulsifying agent Substances 0.000 claims abstract description 14
- 239000004519 grease Substances 0.000 claims abstract description 14
- 230000001333 moisturizer Effects 0.000 claims abstract description 14
- 239000002904 solvent Substances 0.000 claims abstract description 14
- 239000000203 mixture Substances 0.000 claims abstract description 13
- 230000003110 anti-inflammatory effect Effects 0.000 claims abstract description 5
- 230000001775 anti-pathogenic effect Effects 0.000 claims abstract description 4
- 238000003756 stirring Methods 0.000 claims description 54
- 240000007594 Oryza sativa Species 0.000 claims description 19
- 235000007164 Oryza sativa Nutrition 0.000 claims description 19
- 235000009566 rice Nutrition 0.000 claims description 19
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 17
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 claims description 15
- 229940082500 cetostearyl alcohol Drugs 0.000 claims description 14
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 14
- OULAJFUGPPVRBK-UHFFFAOYSA-N tetratriacontyl alcohol Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCO OULAJFUGPPVRBK-UHFFFAOYSA-N 0.000 claims description 14
- 241000220317 Rosa Species 0.000 claims description 11
- 239000002253 acid Substances 0.000 claims description 11
- 239000002285 corn oil Substances 0.000 claims description 11
- 235000005687 corn oil Nutrition 0.000 claims description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 11
- 229920002148 Gellan gum Polymers 0.000 claims description 9
- 235000006484 Paeonia officinalis Nutrition 0.000 claims description 9
- 235000021307 Triticum Nutrition 0.000 claims description 9
- 235000010492 gellan gum Nutrition 0.000 claims description 9
- 239000000216 gellan gum Substances 0.000 claims description 9
- 229930182470 glycoside Natural products 0.000 claims description 9
- 150000002338 glycosides Chemical class 0.000 claims description 9
- CKQVRZJOMJRTOY-UHFFFAOYSA-N octadecanoic acid;propane-1,2,3-triol Chemical compound OCC(O)CO.CCCCCCCCCCCCCCCCCC(O)=O CKQVRZJOMJRTOY-UHFFFAOYSA-N 0.000 claims description 9
- 238000002360 preparation method Methods 0.000 claims description 9
- 239000010902 straw Substances 0.000 claims description 9
- 229920001503 Glucan Polymers 0.000 claims description 8
- 238000004945 emulsification Methods 0.000 claims description 8
- 235000011187 glycerol Nutrition 0.000 claims description 8
- TWNIBLMWSKIRAT-VFUOTHLCSA-N levoglucosan Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@H]2CO[C@@H]1O2 TWNIBLMWSKIRAT-VFUOTHLCSA-N 0.000 claims description 8
- 102000008186 Collagen Human genes 0.000 claims description 7
- 108010035532 Collagen Proteins 0.000 claims description 7
- 235000021355 Stearic acid Nutrition 0.000 claims description 7
- 229920001436 collagen Polymers 0.000 claims description 7
- 229940118127 fucus vesiculosus extract Drugs 0.000 claims description 7
- 230000003301 hydrolyzing effect Effects 0.000 claims description 7
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 claims description 7
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 claims description 7
- 230000003647 oxidation Effects 0.000 claims description 7
- 238000007254 oxidation reaction Methods 0.000 claims description 7
- 239000008117 stearic acid Substances 0.000 claims description 7
- MJYQFWSXKFLTAY-OVEQLNGDSA-N (2r,3r)-2,3-bis[(4-hydroxy-3-methoxyphenyl)methyl]butane-1,4-diol;(2r,3r,4s,5s,6r)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O.C1=C(O)C(OC)=CC(C[C@@H](CO)[C@H](CO)CC=2C=C(OC)C(O)=CC=2)=C1 MJYQFWSXKFLTAY-OVEQLNGDSA-N 0.000 claims description 6
- XDOFQFKRPWOURC-UHFFFAOYSA-N 16-methylheptadecanoic acid Chemical compound CC(C)CCCCCCCCCCCCCCC(O)=O XDOFQFKRPWOURC-UHFFFAOYSA-N 0.000 claims description 6
- 241000195493 Cryptophyta Species 0.000 claims description 6
- 244000042664 Matricaria chamomilla Species 0.000 claims description 6
- 235000004429 Matricaria chamomilla var recutita Nutrition 0.000 claims description 6
- 241001135917 Vitellaria paradoxa Species 0.000 claims description 6
- 235000018936 Vitellaria paradoxa Nutrition 0.000 claims description 6
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims description 6
- 235000013399 edible fruits Nutrition 0.000 claims description 6
- 239000010685 fatty oil Substances 0.000 claims description 6
- 235000004426 flaxseed Nutrition 0.000 claims description 6
- 229940096563 thymus serpyllum extract Drugs 0.000 claims description 6
- 229930003799 tocopherol Natural products 0.000 claims description 6
- 229960001295 tocopherol Drugs 0.000 claims description 6
- 239000011732 tocopherol Substances 0.000 claims description 6
- 235000010384 tocopherol Nutrition 0.000 claims description 6
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 claims description 6
- 240000007817 Olea europaea Species 0.000 claims description 5
- 229920002385 Sodium hyaluronate Polymers 0.000 claims description 5
- 230000008859 change Effects 0.000 claims description 5
- 239000003795 chemical substances by application Substances 0.000 claims description 5
- 239000003599 detergent Substances 0.000 claims description 5
- 239000001947 glycyrrhiza glabra rhizome/root Substances 0.000 claims description 5
- 239000003755 preservative agent Substances 0.000 claims description 5
- 230000002335 preservative effect Effects 0.000 claims description 5
- 239000010499 rapseed oil Substances 0.000 claims description 5
- 239000013535 sea water Substances 0.000 claims description 5
- 229940010747 sodium hyaluronate Drugs 0.000 claims description 5
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims description 5
- 235000015112 vegetable and seed oil Nutrition 0.000 claims description 5
- 240000008042 Zea mays Species 0.000 claims description 4
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims description 4
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims description 4
- 235000005822 corn Nutrition 0.000 claims description 4
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims description 3
- -1 acyl disodium glutamate Chemical compound 0.000 claims description 3
- 239000001257 hydrogen Substances 0.000 claims description 3
- 229910052739 hydrogen Inorganic materials 0.000 claims description 3
- 235000010445 lecithin Nutrition 0.000 claims description 3
- 229940067606 lecithin Drugs 0.000 claims description 3
- 239000000787 lecithin Substances 0.000 claims description 3
- 241000167550 Centella Species 0.000 claims description 2
- 230000000844 anti-bacterial effect Effects 0.000 claims description 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 2
- 244000170916 Paeonia officinalis Species 0.000 claims 2
- 235000019082 Osmanthus Nutrition 0.000 claims 1
- 241000333181 Osmanthus Species 0.000 claims 1
- 244000098338 Triticum aestivum Species 0.000 claims 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000002994 raw material Substances 0.000 claims 1
- 230000003020 moisturizing effect Effects 0.000 abstract description 6
- 230000000694 effects Effects 0.000 abstract description 4
- 239000005556 hormone Substances 0.000 abstract description 3
- 229940088597 hormone Drugs 0.000 abstract description 3
- 230000003266 anti-allergic effect Effects 0.000 abstract description 2
- 229920000832 Cutin Polymers 0.000 abstract 1
- 102000000429 Factor XII Human genes 0.000 abstract 1
- 108010080865 Factor XII Proteins 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 description 9
- 241000209140 Triticum Species 0.000 description 8
- KMSXHXLZXWCJIO-DTUYJQALSA-L disodium (4S)-4-amino-5-dodecanoyloxy-5-oxopentanoate Chemical group N[C@@H](CCC(=O)[O-])C(=O)OC(CCCCCCCCCCC)=O.[Na+].[Na+].C(CCCCCCCCCCC)(=O)OC([C@@H](N)CCC(=O)[O-])=O KMSXHXLZXWCJIO-DTUYJQALSA-L 0.000 description 8
- 241000736199 Paeonia Species 0.000 description 7
- 229920001285 xanthan gum Polymers 0.000 description 7
- 244000044822 Simmondsia californica Species 0.000 description 4
- 235000004433 Simmondsia californica Nutrition 0.000 description 4
- 229930003427 Vitamin E Natural products 0.000 description 4
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 description 4
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 4
- 239000011709 vitamin E Substances 0.000 description 4
- 229940046009 vitamin E Drugs 0.000 description 4
- 235000019165 vitamin E Nutrition 0.000 description 4
- 244000146462 Centella asiatica Species 0.000 description 3
- 235000004032 Centella asiatica Nutrition 0.000 description 3
- 241000227647 Fucus vesiculosus Species 0.000 description 3
- 150000001408 amides Chemical class 0.000 description 3
- YDNKGFDKKRUKPY-JHOUSYSJSA-N C16 ceramide Natural products CCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)C=CCCCCCCCCCCCCC YDNKGFDKKRUKPY-JHOUSYSJSA-N 0.000 description 2
- 102000002322 Egg Proteins Human genes 0.000 description 2
- 108010000912 Egg Proteins Proteins 0.000 description 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 2
- CRJGESKKUOMBCT-VQTJNVASSA-N N-acetylsphinganine Chemical compound CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(C)=O CRJGESKKUOMBCT-VQTJNVASSA-N 0.000 description 2
- 229940106189 ceramide Drugs 0.000 description 2
- ZVEQCJWYRWKARO-UHFFFAOYSA-N ceramide Natural products CCCCCCCCCCCCCCC(O)C(=O)NC(CO)C(O)C=CCCC=C(C)CCCCCCCCC ZVEQCJWYRWKARO-UHFFFAOYSA-N 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 238000005984 hydrogenation reaction Methods 0.000 description 2
- VVGIYYKRAMHVLU-UHFFFAOYSA-N newbouldiamide Natural products CCCCCCCCCCCCCCCCCCCC(O)C(O)C(O)C(CO)NC(=O)CCCCCCCCCCCCCCCCC VVGIYYKRAMHVLU-UHFFFAOYSA-N 0.000 description 2
- 210000004681 ovum Anatomy 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- DCXXMTOCNZCJGO-UHFFFAOYSA-N tristearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCC DCXXMTOCNZCJGO-UHFFFAOYSA-N 0.000 description 2
- RSWGJHLUYNHPMX-UHFFFAOYSA-N 1,4a-dimethyl-7-propan-2-yl-2,3,4,4b,5,6,10,10a-octahydrophenanthrene-1-carboxylic acid Chemical compound C12CCC(C(C)C)=CC2=CCC2C1(C)CCCC2(C)C(O)=O RSWGJHLUYNHPMX-UHFFFAOYSA-N 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 240000005001 Paeonia suffruticosa Species 0.000 description 1
- 235000003889 Paeonia suffruticosa Nutrition 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 230000009285 allergic inflammation Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 229940081733 cetearyl alcohol Drugs 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 239000002480 mineral oil Substances 0.000 description 1
- 235000010446 mineral oil Nutrition 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 230000001537 neural effect Effects 0.000 description 1
- 229940068065 phytosterols Drugs 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000000306 recurrent effect Effects 0.000 description 1
- 230000008591 skin barrier function Effects 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000012209 synthetic fiber Substances 0.000 description 1
- 229920002994 synthetic fiber Polymers 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/68—Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Cosmetics (AREA)
Abstract
本发明提供一种适用于湿疹皮肤的修复霜，具有深层滋润肌肤，增强肌肤免疫能力、修复受损角质、防止激素造成的依耐性皮炎的功效。本发明的修复霜可以使湿疹皮肤得到有效缓解；相比于市售的面霜，本发明的修复霜保湿、抗敏和去红效果更优越。一种适用于湿疹皮肤的修复霜包括以下成分：溶剂20‑65％；油脂6‑34％；乳化剂0.5‑14％；保湿剂12‑36％；修复因子12‑56％；抗炎抑菌成分13‑58％。
Description
技术领域
本发明涉及一种化妆品，主要是皮肤护肤用品，特别是一种适用于湿疹皮肤的修复霜。
背景技术
湿疹是一种由多种内外因素引起的变态反应性炎症性皮肤病。其具有剧烈瘙痒、复发性的临床特征。湿疹的常见内在因素为身体免疫失衡和皮肤屏障功能的损坏，主要外在因素是冷、热温度的刺激、清洁剂、动物毛发、压力、花粉、某些金属、合成纤维及压力的变化。现如今，湿疹无法被治愈，只能通过合理的预防和治疗来控制湿疹的症状。目前，治疗此类疾病的用药一般含有化学或激素类成分，此类成分具有毒副作用且易产生耐药性。
发明内容
本发明所要解决的技术问题通过以下技术方案予以实现：一种适用于湿疹皮肤的修复霜包括以下成分：溶剂20-65％；油脂6-37％；乳化剂0.5-14％；保湿剂12-36％；修复因子12-56％；抗炎抑菌成分13-58％。
所述溶剂为玫瑰花水或者是添加有少量海水的玫瑰花水混合物。
所述乳化剂为氢化卵磷脂、甘油硬脂酸酯、硬脂酸、鲸蜡硬脂醇麦秸苷类中的至少一种。
所述油脂为霍霍巴籽油、角鲨烷、牛油果树果脂油、低芥酸菜子油、鲸蜡硬脂醇中的至少一种。
所述保湿剂为丁二醇、甘油、糙伏毛燕麦籽提取物、水解大米提取物、水解胶原、透明质酸钠中的至少一种。
所述修复因子为奥氏海藻提取物、植物甾醇异硬脂酸酯、生育酚、水解玉米蛋白、稻糠提取物、水解大米蛋白、墨角藻提取物、欧百里香提取物、神经酰胺3、胆甾醇中的至少一种。
所述抗炎抑菌成分为氧化玉米油、燕麦β-葡聚糖、亚麻籽提取物、母菊花提取物、光果甘草根提取物、积雪草提取物、柑橘果皮提取物、芍药根提取物、油橄榄叶提取物、牡丹根提取物中的至少一种。
所述修复霜还包括以下成分：清洁剂0.1-3％；成膜剂0.1-3％；防腐剂0.1-3％。
所述清洁剂为月桂酰谷氨酸二钠；所述成膜剂为结冷胶；所述防腐剂为辛酰羟肟酸。
所述修复霜配方中对保湿抗菌祛湿功能起主要作用的是胆甾醇、植物甾醇异硬脂酸酯、神经酰胺3、墨角藻提取物、氧化玉米油、燕麦β-葡聚糖、积雪草提取物。
所述修复霜中神经酰胺：墨角藻提取物：氧化玉米油比率可以是1-5:2-5:1-6；神经酰胺：墨角藻提取物：氧化玉米油的优选的比例是2-5:3-5:3-5,：神经酰胺：墨角藻提取物：氧化玉米油的最优选的比例是4:4:3。
所述适用于湿疹皮肤的修复霜的制备方法为，将保湿剂和溶剂混合置于容器中，搅拌至70-90℃，待所有组分完全溶解制得a相；将乳化剂和油脂混合置于容器中，搅拌至70-90℃，待所有组分完全溶解制得b相；用真空泵将水相和油相成分通过过滤器分别吸入乳化锅，均质4-5min，搅拌速率50-55r/min，而后保温搅拌15-45min，搅拌速率为40-45r/min；冷却至40-45℃，加入剩余原料，继续搅拌，搅拌速率为35-40r/min，得到所述修复霜。
与现有技术相比，本发明具有的有益效果如下：(1)本发明将具有多重保湿因子，能够改善皮肤水分供给，深层滋润肌肤，补充细胞营养，舒缓皮肤；(2)本发明的修复霜中神经酰胺、植物甾醇等成分，能够在皮肤表面形成有效锁水膜，使粗糙皮肤变得细腻、平滑；(3)本发明的修复霜中含有多重修复因子，可以促性伤口愈合、修复受损肌肤；(4)本发明的修复霜可以使湿疹皮肤得到有效缓解；(5)相比于市售的面霜，本发明的修复霜保湿、抗敏和去红效果更优越；(6)本发明的修复霜无酒精，无色素，无化学合成防腐剂，无矿物油，无激素，无香精，无荧光剂，成分安全，温和不刺激。
具体实施方式
以下结合具体实施例对本发明做出进一步阐述。下面结合具体实施例对本发明作进一步说明，但不作为对本发明的限制。本实施例中没有详细叙述的部分是采用现有技术，行业标准或公知手段。
实施例1
一种适用于湿疹皮肤的保湿霜，它含有的成分及其质量百分比组成为：玫瑰花水20％、丁二醇8％、甘油6％、氧化玉米油6％、牛油果树果脂油8％、糙伏毛燕麦籽提取物8％、燕麦β-葡聚糖1％、奥氏海藻提取物3％、植物甾醇异硬脂酸酯2％、生育酚(维生素E)1％、氢化卵磷脂0.3％、水解玉米蛋白2％、稻糠提取物2％、水解大米提取物5％、亚麻籽提取物5％、水解大米蛋白2％、母菊花提取物5％、水解胶原2％、透明质酸钠3％、甘油硬脂酸酯0.1％、鲸蜡硬脂醇0.1％、硬脂酸0.1％、月桂酰谷氨酸二钠1.3％、鲸蜡硬脂醇麦秸苷类0.1％、结冷胶3％、黄原胶3％、辛酰羟肟酸3％。
制备过程为：将保湿剂和溶剂混合置于容器中，搅拌至70℃，待所有组分完全溶解制得a相；将乳化剂和油脂混合置于容器中，搅拌至70℃，待所有组分完全溶解制得b相；用真空泵将水相和油相成分通过过滤器分别吸入乳化锅，均质4.5min，搅拌速率52r/min，而后保温搅拌45min，搅拌速率为47r/min；冷却至42℃，加入剩余原料，继续搅拌，搅拌速率为42r/min，得到所述修复霜。
实施例2
一种适用于湿疹皮肤的保湿霜，它含有的成分及其质量百分比组成为：玫瑰花水54％、甘油5％、氧化玉米油1％、霍霍巴籽油2％、角鲨烷3％、糙伏毛燕麦籽提取物3％、奥氏海藻提取物2％、低芥酸菜子油1％、植物甾醇异硬脂酸酯3％、生育酚(维生素E)2％、氢化卵磷脂0.3％、海水2％、稻糠提取物1％、墨角藻提取物2％、光果甘草根提取物5％、积雪草提取物5％、柑橘果皮提取物2％、欧百里香提取物2％、水解胶原4％、甘油硬脂酸酯0.1％、硬脂酸0.1％、月桂酰谷氨酸二钠0.1％、鲸蜡硬脂醇麦秸苷类0.1％、结冷胶0.1％、黄原胶0.1％、辛酰羟肟酸0.1％。
制备过程为：将保湿剂和溶剂混合置于容器中，搅拌至85℃，待所有组分完全溶解制得a相；将乳化剂和油脂混合置于容器中，搅拌至85℃，待所有组分完全溶解制得b相；用真空泵将水相和油相成分通过过滤器分别吸入乳化锅，均质4min，搅拌速率50r/min，而后保温搅拌30min，搅拌速率为45r/min；冷却至45℃，加入剩余原料，继续搅拌，搅拌速率为40r/min，得到所述修复霜。
实施例3
一种适用于湿疹皮肤的保湿霜，它含有的成分及其质量百分比组成为：玫瑰花水20％、甘油5％、霍霍巴籽油4％、角鲨烷0％、牛油果树果脂油2％、糙伏毛燕麦籽提取物3％、燕麦β-葡聚糖8％、奥氏海藻提取物8％、植物甾醇异硬脂酸酯6％、生育酚(维生素E)3％、氢化卵磷脂0.2％、水解玉米蛋白5％、海水4％、稻糠提取物5％、水解大米蛋白5％、墨角藻提取物5％、柑橘果皮提取物3％、欧百里香提取物3％、水解胶原4％、芍药根提取物2％、神经酰胺3 1.3％、甘油硬脂酸酯0.1％、硬脂酸0.1％、月桂酰谷氨酸二钠0.1％、鲸蜡硬脂醇麦秸苷类0.1％、结冷胶2％、黄原胶1％、辛酰羟肟酸0.1％。
制备过程为：将保湿剂和溶剂混合置于容器中，搅拌至90℃，待所有组分完全溶解制得a相；将乳化剂和油脂混合置于容器中，搅拌至90℃，待所有组分完全溶解制得b相；用真空泵将水相和油相成分通过过滤器分别吸入乳化锅，均质5min，搅拌速率55r/min，而后保温搅拌15min，搅拌速率为50r/min；冷却至40℃，加入剩余原料，继续搅拌，搅拌速率为45r/min，得到所述修复霜。
实施例4
一种适用于湿疹皮肤的保湿霜，它含有的成分及其质量百分比组成为：玫瑰花水34％、甘油5％、角鲨烷4％、糙伏毛燕麦籽提取物2％、植物甾醇异硬脂酸酯1％、氢化卵磷脂5％、海水5％、水解大米提取物2％、亚麻籽提取物1％、母菊花提取物2％、光果甘草根提取物2％、积雪草提取物3％、柑橘果皮提取物5％、欧百里香提取物5％、水解胶原3％、神经酰胺3 1％、胆甾醇5％、甘油硬脂酸酯3％、鲸蜡硬脂醇2％、硬脂酸3％、月桂酰谷氨酸二钠2.4％、鲸蜡硬脂醇麦秸苷类3％、结冷胶0.1％、黄原胶1.3％、辛酰羟肟酸0.2％
制备过程为：将保湿剂和溶剂混合置于容器中，搅拌至80℃，待所有组分完全溶解制得a相；将乳化剂和油脂混合置于容器中，搅拌至80℃，待所有组分完全溶解制得b相；用真空泵将水相和油相成分通过过滤器分别吸入乳化锅，均质5min，搅拌速率55r/min，而后保温搅拌30min，搅拌速率为50r/min；冷却至40℃，加入剩余原料，继续搅拌，搅拌速率为45r/min，得到所述修复霜。
实施例5
一种适用于湿疹皮肤的保湿霜，它含有的成分及其质量百分比组成为：玫瑰花水20％、丁二醇6％、甘油5％、氧化玉米油5％、牛油果树果脂油6％、燕麦β-葡聚糖7％、氢化卵磷脂0.3％、稻糠提取物4％、亚麻籽提取物4％、水解大米蛋白3％、墨角藻提取物4％、积雪草提取物2％、柑橘果皮提取物4％、欧百里香提取物4％、芍药根提取物5％、油橄榄叶提取物5％、牡丹根提取物5％、神经酰胺3 3％、胆甾醇2％、透明质酸钠1％、甘油硬脂酸酯0.1％、月桂酰谷氨酸二钠0.1％、鲸蜡硬脂醇麦秸苷类0.1％、结冷胶1％、黄原胶3％、辛酰羟肟酸0.4％
制备过程为：将保湿剂和溶剂混合置于容器中，搅拌至70℃，待所有组分完全溶解制得a相；将乳化剂和油脂混合置于容器中，搅拌至70℃，待所有组分完全溶解制得b相；用真空泵将水相和油相成分通过过滤器分别吸入乳化锅，均质4.5min，搅拌速率52r/min，而后保温搅拌45min，搅拌速率为47r/min；冷却至42℃，加入剩余原料，继续搅拌，搅拌速率为42r/min，得到所述修复霜。
实施例6
一种适用于湿疹皮肤的保湿霜，它含有的成分及其质量百分比组成为：玫瑰花水20％、氧化玉米油2％、霍霍巴籽油10％、角鲨烷8％、牛油果树果脂油4％、糙伏毛燕麦籽提取物7％、燕麦β-葡聚糖2％、奥氏海藻提取物7％、低芥酸菜子油5％、生育酚(维生素E)0.5％、氢化卵磷脂1％、稻糠提取物1％、水解大米提取物4％、母菊花提取物4％、水解胶原5％、油橄榄叶提取物2％、牡丹根提取物2％、神经酰胺3 5％、胆甾醇2％、透明质酸钠0.1％、甘油硬脂酸酯2％、鲸蜡硬脂醇1％、硬脂酸1％、月桂酰谷氨酸二钠0.1％、鲸蜡硬脂醇麦秸苷类0.2％、结冷胶3％、黄原胶0.1％、辛酰羟肟酸1％
制备过程为：将保湿剂和溶剂混合置于容器中，搅拌至85℃，待所有组分完全溶解制得a相；将乳化剂和油脂混合置于容器中，搅拌至85℃，待所有组分完全溶解制得b相；用真空泵将水相和油相成分通过过滤器分别吸入乳化锅，均质4min，搅拌速率50r/min，而后保温搅拌30min，搅拌速率为45r/min；冷却至45℃，加入剩余原料，继续搅拌，搅拌速率为40r/min，得到所述修复霜。
实施例7
一种适用于湿疹皮肤的保湿霜，它含有的成分及其质量百分比组成为：玫瑰花水20％、丁二醇7％、甘油7％、氧化玉米油3％、角鲨烷7％、燕麦β-葡聚糖4.6％、低芥酸菜子油2％、氢化卵磷脂4％、水解大米提取物1％、亚麻籽提取物3％、水解大米蛋白4％、墨角藻提取物4％、母菊花提取物3％、光果甘草根提取物4％、芍药根提取物4％、油橄榄叶提取物2％、牡丹根提取物4％、神经酰胺3 4％、透明质酸钠2％、甘油硬脂酸酯3％、鲸蜡硬脂醇3％、硬脂酸2％、月桂酰谷氨酸二钠0.1％、鲸蜡硬脂醇麦秸苷类2％、结冷胶0.1％、黄原胶0.1％、辛酰羟肟酸0.1％.
制备过程为：将保湿剂和溶剂混合置于容器中，搅拌至80℃，待所有组分完全溶解制得a相；将乳化剂和油脂混合置于容器中，搅拌至80℃，待所有组分完全溶解制得b相；用真空泵将水相和油相成分通过过滤器分别吸入乳化锅，均质5min，搅拌速率55r/min，而后保温搅拌30min，搅拌速率为50r/min；冷却至40℃，加入剩余原料，继续搅拌，搅拌速率为45r/min，得到所述修复霜。
虽然本发明己以实施例公开如上，但其并非用以限定本发明的保护范围，任何熟悉该项技术的技术人员，在不脱离本发明的构思和范围内所作的更动与润饰，均应属于本发明的保护范围。
Claims (10)
1.一种适用于湿疹皮肤的修复霜，其特征在于：所述修复霜包括以下成分：
溶剂20-65％；
油脂6-37％；
乳化剂0.5-14％；
保湿剂12-36％；
修复因子12-56％；
抗炎抑菌成分13-58％。
2.根据权利要求1所述的一种适用于湿疹皮肤的修复霜，其特征在于：所述溶剂为玫瑰花水或者是添加有少量海水的玫瑰花水混合物。
3.根据权利要求1所述的一种适用于湿疹皮肤的修复霜，其特征在于：所述乳化剂为氢化卵磷脂、甘油硬脂酸酯、硬脂酸、鲸蜡硬脂醇麦秸苷类中的至少一种。
4.根据权利要求1所述的一种适用于湿疹皮肤的修复霜，其特征在于：所述油脂为霍霍巴籽油、角鲨烷、牛油果树果脂油、低芥酸菜子油、鲸蜡硬脂醇中的至少一种。
5.根据权利要求1所述的一种适用于湿疹皮肤的修复霜，其特征在于：所述保湿剂为丁二醇、甘油、糙伏毛燕麦籽提取物、水解大米提取物、水解胶原、透明质酸钠中的至少一种。
6.根据权利要求1所述的一种适用于湿疹皮肤的修复霜，其特征在于：所述修复因子为奥氏海藻提取物、植物甾醇异硬脂酸酯、生育酚、水解玉米蛋白、稻糠提取物、水解大米蛋白、墨角藻提取物、欧百里香提取物、神经酰胺3、胆甾醇中的至少一种。
7.根据权利要求1所述的一种适用于湿疹皮肤的修复霜，其特征在于：所述抗炎抑菌成分为氧化玉米油、燕麦β-葡聚糖、亚麻籽提取物、母菊花提取物、光果甘草根提取物、积雪草提取物、柑橘果皮提取物、芍药根提取物、油橄榄叶提取物、牡丹根提取物中的至少一种。
8.根据权利要求1所述的一种适用于湿疹皮肤的修复霜，其特征在于：所述修复霜还包括以下成分：
清洁剂0.1-3％；
成膜剂0.1-3％；
防腐剂0.1-3％。
9.根据权利要求8所述的一种适用于湿疹皮肤的修复霜，其特征在于：所述清洁剂为月桂酰谷氨酸二钠；所述成膜剂为结冷胶；所述防腐剂为辛酰羟肟酸。
10.一种制备如权利要求1-9任一项所述适用于湿疹皮肤的修复霜的方法，其特征在于，所述制备方法包括以下步骤：将保湿剂和溶剂混合置于容器中，搅拌至70-90℃，待所有组分完全溶解制得a相；将乳化剂和油脂混合置于容器中，搅拌至70-90℃，待所有组分完全溶解制得b相；用真空泵将水相和油相成分通过过滤器分别吸入乳化锅，均质4-5min，搅拌速率50-55r/min，而后保温搅拌15-45min，搅拌速率为40-45r/min；冷却至40-45℃，加入剩余原料，继续搅拌，搅拌速率为35-40r/min，得到所述修复霜。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810111952.9A CN108245442A (zh) | 2018-02-05 | 2018-02-05 | 一种适用于湿疹皮肤的修复霜 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810111952.9A CN108245442A (zh) | 2018-02-05 | 2018-02-05 | 一种适用于湿疹皮肤的修复霜 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108245442A true CN108245442A (zh) | 2018-07-06 |
Family
ID=62744194
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810111952.9A Pending CN108245442A (zh) | 2018-02-05 | 2018-02-05 | 一种适用于湿疹皮肤的修复霜 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108245442A (zh) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109010244A (zh) * | 2018-09-05 | 2018-12-18 | 广州睿森生物科技有限公司 | 一种包埋抗敏修复成分的纳米粒子及其制备方法 |
| CN109431943A (zh) * | 2018-12-25 | 2019-03-08 | 广东润洁日化有限公司 | 一种针对婴幼儿湿疹的修护膏及其制备 |
| CN110897906A (zh) * | 2019-11-19 | 2020-03-24 | 天津郁美净集团有限公司 | 皮肤屏障修复组合物及其应用 |
| CN113143827A (zh) * | 2021-04-13 | 2021-07-23 | 陈鉴武 | 一种抗衰老防皱面霜及其制备方法 |
| CN113730490A (zh) * | 2019-10-28 | 2021-12-03 | 深圳市远光宙科技有限公司 | 一种具有缓解皮肤湿疹症状的组合物的制备方法 |
| CN113952259A (zh) * | 2021-12-09 | 2022-01-21 | 广州栋方生物科技股份有限公司 | 一种舒缓修复精华油及其制备方法和应用 |
| CN114288194A (zh) * | 2021-12-30 | 2022-04-08 | 彭氏(惠州)实业发展有限公司 | 一种不含去离子水的双层护肤精华液及其制备方法 |
| CN115350130A (zh) * | 2022-09-22 | 2022-11-18 | 欧诗漫生物股份有限公司 | 一种具有即时舒缓作用的化妆品组合物、化妆品及其制备方法 |
| CN115381761A (zh) * | 2022-08-12 | 2022-11-25 | 深圳阿尔法生物科技有限公司 | 一种海洋胶原蛋白修复霜 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106074663A (zh) * | 2016-08-24 | 2016-11-09 | 广州睿森生物科技有限公司 | 一种植物提取物及激素依赖性皮炎修复霜 |
| CN106726986A (zh) * | 2016-12-28 | 2017-05-31 | 广州市聚吉科绿色化学共性技术研究院有限公司 | 一种婴儿湿疹膏 |
| CN107115213A (zh) * | 2017-04-28 | 2017-09-01 | 广州瑞誉化工科技有限公司 | 一种具有湿疹修复功能的润肤霜 |
-
2018
- 2018-02-05 CN CN201810111952.9A patent/CN108245442A/zh active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106074663A (zh) * | 2016-08-24 | 2016-11-09 | 广州睿森生物科技有限公司 | 一种植物提取物及激素依赖性皮炎修复霜 |
| CN106726986A (zh) * | 2016-12-28 | 2017-05-31 | 广州市聚吉科绿色化学共性技术研究院有限公司 | 一种婴儿湿疹膏 |
| CN107115213A (zh) * | 2017-04-28 | 2017-09-01 | 广州瑞誉化工科技有限公司 | 一种具有湿疹修复功能的润肤霜 |
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109010244A (zh) * | 2018-09-05 | 2018-12-18 | 广州睿森生物科技有限公司 | 一种包埋抗敏修复成分的纳米粒子及其制备方法 |
| CN109010244B (zh) * | 2018-09-05 | 2021-06-29 | 广州睿森生物科技有限公司 | 一种包埋抗敏修复成分的纳米粒子及其制备方法 |
| CN109431943B (zh) * | 2018-12-25 | 2021-11-19 | 广东润洁日化有限公司 | 一种针对婴幼儿湿疹的修护膏及其制备 |
| CN109431943A (zh) * | 2018-12-25 | 2019-03-08 | 广东润洁日化有限公司 | 一种针对婴幼儿湿疹的修护膏及其制备 |
| CN113730490A (zh) * | 2019-10-28 | 2021-12-03 | 深圳市远光宙科技有限公司 | 一种具有缓解皮肤湿疹症状的组合物的制备方法 |
| CN113730490B (zh) * | 2019-10-28 | 2022-03-04 | 深圳市远光宙科技有限公司 | 一种具有缓解皮肤湿疹症状的组合物的制备方法 |
| CN110897906A (zh) * | 2019-11-19 | 2020-03-24 | 天津郁美净集团有限公司 | 皮肤屏障修复组合物及其应用 |
| CN113143827A (zh) * | 2021-04-13 | 2021-07-23 | 陈鉴武 | 一种抗衰老防皱面霜及其制备方法 |
| CN113952259A (zh) * | 2021-12-09 | 2022-01-21 | 广州栋方生物科技股份有限公司 | 一种舒缓修复精华油及其制备方法和应用 |
| CN114288194A (zh) * | 2021-12-30 | 2022-04-08 | 彭氏(惠州)实业发展有限公司 | 一种不含去离子水的双层护肤精华液及其制备方法 |
| CN114288194B (zh) * | 2021-12-30 | 2024-03-22 | 彭氏(惠州)实业发展有限公司 | 一种不含去离子水的双层护肤精华液及其制备方法 |
| CN115381761A (zh) * | 2022-08-12 | 2022-11-25 | 深圳阿尔法生物科技有限公司 | 一种海洋胶原蛋白修复霜 |
| CN115350130A (zh) * | 2022-09-22 | 2022-11-18 | 欧诗漫生物股份有限公司 | 一种具有即时舒缓作用的化妆品组合物、化妆品及其制备方法 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN108245442A (zh) | 一种适用于湿疹皮肤的修复霜 | |
| CN105616283B (zh) | 一种植物精粹修护面霜 | |
| CN106074663B (zh) | 一种植物提取物及激素依赖性皮炎修复霜 | |
| CN103976907B (zh) | 一种包含具有舒缓抗敏作用的组合物的化妆品、其制备方法及应用 | |
| CN103705421B (zh) | 一种牛奶补水抗衰老霜及其制造方法 | |
| CN115607510B (zh) | 一种高浓度齐墩果酸纳米乳组合物及制备方法 | |
| CN110151650A (zh) | 一种含七叶树复合活性成分的祛红血丝乳液及其制备方法 | |
| KR102652806B1 (ko) | 헴프씨드오일을 함유한 아토피 개선 효능을 갖는 화장품 조성물 제조방법 및 그에 의해 제조된 헴프씨드오일을 함유한 아토피 개선 효능을 갖는 화장품 조성물 | |
| CN105902418A (zh) | 一种仿皮脂基质、包含仿皮脂基质的外用制剂及其应用 | |
| KR20200029981A (ko) | 아토피 예방 또는 개선용 조성물 및 이의 제조방법 | |
| Sonalkar et al. | Formulation and evaluation of polyherbal cosmetic cream | |
| CN107184448A (zh) | 一种具有预防痘痕生成的祛痘霜 | |
| US9579357B1 (en) | Therapeutic compositions | |
| KR101000695B1 (ko) | 항염 및 피부자극완화 효과가 있는 천연 식물의혼합추출물을 함유하는 화장료 조성물 | |
| Baldi et al. | Synergistic use of bioactive agents for the management of different skin conditions: an overview of biological activities. | |
| CN107157910A (zh) | 一种具有双重保湿功效的护肤组合物及其制备方法与应用 | |
| CN106333909B (zh) | 一种淡化面部红血丝修复肌肤的乳液及其制备方法 | |
| CN107823021A (zh) | 一种鳄鱼油保湿修复乳液及其制备方法 | |
| KR102214985B1 (ko) | 식물추출물 또는 이의 분획물을 유효성분으로 함유하는 피부 상태 개선용 조성물 | |
| CN108785196A (zh) | 一种用于抚平痘坑痘印的组合物及其在化妆品中的应用 | |
| CN107137336A (zh) | 一种祛痘中药面膜及其制备方法 | |
| KR101065356B1 (ko) | 동백박(동백종실 껍질 분말) 및 그 추출물의 이용 | |
| CN101601637B (zh) | 柚叶提取物及含有柚叶提取物的护肤霜 | |
| KR101211754B1 (ko) | 천연 추출물을 함유하는 스트레스성 여드름 개선용 화장료 조성물 | |
| CN113876679B (zh) | 具有保湿和舒缓敏感肌肤的多效组合物及精华素和制备方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180706 |