CN1082406A - Compound vitamin A acid oil - Google Patents
Compound vitamin A acid oil Download PDFInfo
- Publication number
- CN1082406A CN1082406A CN 92114435 CN92114435A CN1082406A CN 1082406 A CN1082406 A CN 1082406A CN 92114435 CN92114435 CN 92114435 CN 92114435 A CN92114435 A CN 92114435A CN 1082406 A CN1082406 A CN 1082406A
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- China
- Prior art keywords
- acne
- treatment
- compound vitamin
- acid oil
- present
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Abstract
The present invention relates to a kind of externally applied liniment of new treatment acne, compound vitamin A acid oil.It is made up of zinc sulfate, retinoic acid, diethylstilbestrol and glycerol.Use it on the ultrasonic beautifying device of treatment acne, can penetrate skin well, absorbance height, curative effect are fine.Composition of the present invention is simple, and cost is low, and side effect is little, the curative effect height, and treatment time is short, and cure rate is 100%, is that the ideal external of a treatment acne penetrates liniment.
Description
The present invention relates to a kind of externally applied liniment compound vitamin A acid oil that is used for the treatment of acne, penetrate liniment especially for the external that penetrates medicine on the ultrasonic beautifying device of treatment acne.
Acne is because smegma is vigorous, unable excreting and the disease that causes.Initial stage is little acne, becomes acne vulgaris late period.The sickness rate of acne is very high, and especially adolescence is more.Some present Therapeutic Method are not ideal.As the externally applied liniment class, BeiJing ZhangGuang's 101 acne Herba Senecionis Dianthui, what absorb during use is few, does not reach skin sometimes and refers in the gland that effective percentage only reaches 30～40%, and cost is higher." acyl relaxes " that Beijing doube bridge pharmaceutical factory produces do not reach during use in the sebaceous gland yet, and absorption few will take effect in 1～2 month, and effective percentage only reaches about 30%.And for example U.S. Patent application NS4713242 has reported a kind of externally applied liniment for the treatment of the acne of acne, contains sulfathiazole, zinc oxide, vaseline; The patent application EP-281812 of EUROPEAN PATENT OFFICE has also reported a kind of liniment for the treatment of acne, contains keratolytic, oxidant, and antiinflammatory, hemiamic acid or aminoglucose, all there are the problems referred to above in they.
The object of the present invention is to provide a kind of externally applied liniment of new treatment acne, compound vitamin A acid oil, it has advantages such as prescription is simple, and cost is low, and side effect is little, (grant patent by Patent Office of the People's Republic of China with ultrasonic beautifying device, the patent No. 89219595.9) penetrates in facial skin and hold up on the focus of acne, make medicine can be good at being absorbed, the recovery from illness in 5～10 days of treatment back, effective percentage reaches 100%, thereby has solved the problems referred to above.
Feature of the present invention is a kind of compound vitamin A acid oil that is used for the treatment of acne, contains zinc sulfate, glycerol, it is characterized in that of the present invention consisting of:
Zinc sulfate 2.000～3.000%
Retinoic acid 0.040～0.050%
Estrogen 0.004～0.006%
All the other are glycerol, and total amount is 100%.
Estrogen recited above is with the diethylstilbestrol best results.
Zinc sulfate has convergence, antiinflammatory action, and the effect of trace element supplement zinc is arranged, and diethylstilbestrol is a kind of of estrogen, and the effect of additional estrogen is arranged, and proves that in recent years supply estrogen can reduce the development of acne; Retinoic acid is a structurally similar compounds of vitamin A, and the effect of additional skin vitamin A treatment acne is arranged.Compound vitamin A acid oil provided by the invention penetrates skin with ultrasonic beautifying device, and the frequency of ultrasonic beautifying device is 2.2MHz, and the depth of penetration is 1.5cm, just in time reaches before and after the sebaceous gland, play convergence, antiinflammatory action to secreting vigorous sebaceous gland, so curative effect is fine.
Below tabulation provides the present invention and existing Comparative Examples for the treatment of the externally applied liniment of acne.
Embodiment 1. gets 4 milligrams of diethylstilbestrols, adds mix homogeneously in 100 milliliters of glycerol, with after stirring evenly in the 0.04 gram retinoic acid adding mixture, adds 3 gram zinc sulfate again, stirs evenly.About 18 ℃ of room temperatures; Place and to use after 24 hours.
Embodiment 2. presses embodiment 1 same method with following prescription and prepares.
Retinoic acid 0.05 gram
Zinc sulfate 2 grams
6 milligrams of diethylstilbestrols
100 milliliters of glycerol
The invention has the advantages that the composition of this externally applied liniment is simple, preparation is easy, and cost is low, side effect is little, be used for to penetrate well skin on the ultrasonic beautifying device, reach before and after the sebaceous glands, can restrain the vigorous sebaceous glands of secretion, so the absorptivity height, treatment time is short, and curative effect can reach 100%.
Claims (2)
1, a kind of compound vitamin A acid oil that is used for the treatment of acne contains zinc sulfate, glycerol, it is characterized in that of the present invention consisting of:
Zinc sulfate 2.000～3.000%
Retinoic acid 0.040～0.050%
Estrogen 0.004～0.006%
All the other are glycerol, and total amount is 100%.
2, externally applied liniment according to claim 1 is characterized in that said estrogen is diethylstilbestrol.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 92114435 CN1082406A (en) | 1992-12-13 | 1992-12-13 | Compound vitamin A acid oil |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 92114435 CN1082406A (en) | 1992-12-13 | 1992-12-13 | Compound vitamin A acid oil |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1082406A true CN1082406A (en) | 1994-02-23 |
Family
ID=4946930
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 92114435 Pending CN1082406A (en) | 1992-12-13 | 1992-12-13 | Compound vitamin A acid oil |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1082406A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000032155A2 (en) * | 1998-12-04 | 2000-06-08 | Johnson And Johnson Consumer Companies, Inc. | Skin care compositions containing zinc salts and retinoids |
| US10406383B2 (en) | 2004-10-11 | 2019-09-10 | Carewear Corp. | Apparatus for treatment of dermatological conditions |
| US11517578B1 (en) * | 2021-07-29 | 2022-12-06 | Innomed Technologies, Inc. | Topical formulations containing erythritol and methods of treating skin conditions |
-
1992
- 1992-12-13 CN CN 92114435 patent/CN1082406A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000032155A2 (en) * | 1998-12-04 | 2000-06-08 | Johnson And Johnson Consumer Companies, Inc. | Skin care compositions containing zinc salts and retinoids |
| WO2000032155A3 (en) * | 1998-12-04 | 2000-11-23 | Johnson & Johnson Consumer | Skin care compositions containing zinc salts and retinoids |
| US10406383B2 (en) | 2004-10-11 | 2019-09-10 | Carewear Corp. | Apparatus for treatment of dermatological conditions |
| US11517578B1 (en) * | 2021-07-29 | 2022-12-06 | Innomed Technologies, Inc. | Topical formulations containing erythritol and methods of treating skin conditions |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |