CN108236667A - It quenches one's thirst mind-tranquilizing formulation - Google Patents

It quenches one's thirst mind-tranquilizing formulation Download PDF

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CN108236667A
CN108236667A CN201611209866.9A CN201611209866A CN108236667A CN 108236667 A CN108236667 A CN 108236667A CN 201611209866 A CN201611209866 A CN 201611209866A CN 108236667 A CN108236667 A CN 108236667A
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grams
radix
chinese
chinese medicine
seed
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赵巧云
王德伍
赵青朝
赵青团
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Zhengzhou Tiandiren Agricultural And Sideline Products Co Ltd
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Zhengzhou Tiandiren Agricultural And Sideline Products Co Ltd
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
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Abstract

The invention discloses one kind for treating diabetes innerwear Chinese medicine preparation, which is characterized in that the Chinese medicine material and parts by weight of selection be respectively:30 grams of spina date seed, 25 grams of the seed of Oriental arborvitae, 25 grams of Radix Ophiopogonis, 25 grams of Schisandra chinensis, 30 grams of the fruit of Chinese wolfberry, 20 grams of ginseng, 15 grams of radix rehmanniae recen, 15 grams of the coptis, 18 grams of the root bark of Chinese wolf-berry, 20 grams of Radix Astragali, 25 grams of pueraria lobata, 20 grams of Radix Salviae Miltiorrhizae, 19 grams of Fructus Forsythiae, 10 grams of Cortex Magnoliae Officinalis, 20 grams of betel nut, 20 grams of selfheal, 23 grams of lycopodium calvatum, 18 grams of scorpio.Raw medicinal material pharmacological property effect selected by the present invention is complementary, evaded the mutual inhibition of compatibility between drug, mutual restraint between two drugs, the mutual-detoxication choosing, make drug mutual reinforcement between, mutually make effect notable, there is Yin-nourishing and body fluid promoting, clearing heat and cooling blood.Orally taken for curing diabetes have definite curative effect.

Description

It quenches one's thirst mind-tranquilizing formulation
Technical field
The present invention relates to the field of Chinese medicines, and in particular to one kind is quenched one's thirst mind-tranquilizing formulation, for treating diabetes traditional Chinese medicine for oral administration system Agent has effects that Yin-nourishing and body fluid promoting, clearing heat and cooling blood.
Background technology
Diabetes are one group of metabolic diseases characterized by hyperglycemia.Hyperglycemia be then due to defect of insulin secretion or Its biological effect is damaged, or both have concurrently and cause.Long-standing hyperglycemia during diabetes, cause various tissues, particularly eye, Kidney, heart, blood vessel, the chronic lesion of nerve, dysfunction.1. inherent cause:There is apparent lose in 1 type or diabetes B It passes heterogeneous.There are family morbidity tendency, 1/4~1/2 patients Diabetes family history for diabetes.Clinically at least 60 kinds with On genetic syndrome can be with diabetes.Type 1 diabetes have multiple DNA sites to participate in morbidity, wherein in HLA antigen genes DQ loci polymorphism relationships are the closest.In diabetes B it has been found that a variety of specific gene mutations, such as insulin gene, pancreas Island element acceptor gene, glucokinase gene, chondriogen etc..2. environmental factor:Feed is excessive, and physical exertion reduction causes Obesity be the most important environmental factor of diabetes B, make to have the individual easily morbidity of diabetes B genetic predisposition.1 type There are immune system abnormalities by diabetic, are led after the certain viruses such as infection such as Coxsackie virus, rubella virus, parotid gland virus Autoimmune response is caused, destroys insulin β cells.
Invention content
The present invention relates to the field of Chinese medicines, and in particular to one kind has enriching yin life for treating diabetes innerwear Chinese medicine preparation The effect of Tianjin, clearing heat and cooling blood.It is for oral administration, it can be used for treating diabetes, there is definite curative effect.
Present invention employs following technical solutions to achieve the above object:The medicinal material of Chinese medicine preparation selection of the present invention And parts by weight are respectively:30 grams of spina date seed, 25 grams of the seed of Oriental arborvitae, 25 grams of Radix Ophiopogonis, 25 grams of Schisandra chinensis, 30 grams of the fruit of Chinese wolfberry, 20 grams of ginseng, 15 grams of radix rehmanniae recen, 15 grams of the coptis, 18 grams of the root bark of Chinese wolf-berry, 20 grams of Radix Astragali, 25 grams of pueraria lobata, 20 grams of Radix Salviae Miltiorrhizae, 19 grams of Fructus Forsythiae, 10 grams of Cortex Magnoliae Officinalis, 20 grams of betel nut, 20 grams of selfheal, 23 grams of lycopodium calvatum, 18 grams of scorpio.
In the Chinese medicine material that the present invention selects:Spina date seed:It is sweet in flavor, sour, it is mild-natured.Conscience can be nourished, is calmed the nerves, arrest sweating.There is town Quiet, hypnosis, analgesia, anticonvulsant action;There is certain antihypertensive effect;There is excitation to uterus.
The seed of Oriental arborvitae:About 14 % are moored containing fat, mostly unrighted acid forms, also containing a small amount of volatile oil, saponin, egg White matter, calcium, phosphorus, iron multivitamin etc..Seed of Oriental arborvitae flat property and sweet taste.Has the effect of mental-tranquilization, relax bowel.It controls palpitation with fear, lose The diseases such as dormancy, seminal emission, night sweat, constipation.
Radix Ophiopogonis:【Drug character】The product are in spindle, and both ends are slightly sharp, long 1.5~3cm, 0.3~0.6cm of diameter.Surface is yellow It is white or faint yellow, there is thin longitudinal grin.Matter is flexible, and section yellow-white, translucent, center pillar is tiny.Gas micro-perfume, sweet in flavor, slight bitter.【Property Taste channel tropism】Sweet, slight bitter is slightly cold.The thoughts of returning home, lung, stomach.【Function is with curing mainly】Nourishing Yin and promoting production of body fluid, moistening lung clears away heart-fire.For dryness of the lung dry cough, Cough for deficiency of Yin consumptive disease, larynx numbness pharyngalgia, injury thirst, Heat Diabetes, vexed insomnia, dry constipation of intestines.【Efficacy of drugs】1. replenishing the vital essence and removing heat is controlled It treats yin asthenia generating intrinsic heat or pyreticosis disease hinders Tianjin, restlessness and thirst.2. cough caused by the treatment dry-heat impairing lung that moistens the lung and relieve the cough, phlegm is thick, the circulation of vital energy in the wrong direction.
Schisandra chinensis:It with anti-inflammatory, astringes the lung, nourshing kidney is promoted the production of body fluid, and receives sweat, puckery essence.It controls the deficiency syndrome of the lung to breath with cough, thirst, spontaneous perspiration, steal Sweat, internal lesion caused by overexertion is thin thin, emission, protracted dysentery and diarrhea.
The fruit of Chinese wolfberry:【Nature and flavor】Sweet and neutral.【Channel tropism】Return liver and kidney channel.【Major function】It is nourishing liver and kidney, benefiting shrewd head.For void Labor essence is lost, soreness of waist and knee joint, dizziness and tinnitus, Heat Diabetes, blood deficiency chlorosis, blurred vision.
Ginseng:【Meridian distribution of property and flavor】Mild-natured, sweet in flavor, slight bitter, tepor.Returns spleen, lung channel, the heart channel of Hang-Shaoyin.【Effect】It reinforces vital energy, multiple arteries and veins Prevent prolapse reinforces the spleen to benefit the lung, and promotes the production of body fluid to quench thirst, tranquilize the mind and promote the intelligence.【It cures mainly】Internal lesion caused by overexertion is deficient, deficiency of food, burnout, regurgitation and emesis, stool lingering diarrhea, void Cough and asthma rush, spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, impotence, frequent micturition, quench one's thirst, woman uterine bleeding, infantile chronic fright and it is empty long not It is multiple, the disease of all qi-blood-body fluid deficiencies.
Radix rehmanniae recen:Sweet in flavor, bitter, cold in nature enters the heart, liver and kidney channel.【Effect】Clearing heat and promoting fluid enriching yin, blood-nourishing.【It cures mainly】It controls Fever due to yin deficiency is quenched one's thirst, and is spitted blood, bleeding from five sense organs or subcutaneous tissue, metrorrhagia, irregular menstruation, fetal irritability, impairment of yin constipation.Clearing heat and cooling blood, yin-nourishing are promoted the production of body fluid;With In pyreticosis polydipsia, spot dermexanthesis, yin asthenia generating intrinsic heat, haematemesis, bleeding from five sense organs or subcutaneous tissue, diabetes, catarrhal jaundice.
The coptis:Effect:Heat-clearing and damp-drying drug, purging intense heat and detonicating.For damp and hot feeling of fullness, acid regurgitation is vomitted, rush down dysentery, jaundice, unconsciousness due to high fever, Heart-fire hyperactivity, dysphoria and insomnia, blood-head tells nosebleed, hot eyes, toothache are quenched one's thirst, carbuncle swells furunculosis;Eczema, wet sore are controlled outside, duct is suppurated.Wine It is burning hot that the coptis is apt to the clear part of the body cavity above the diaphragm housing the heart and lungs.For hot eyes, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach anti-vomiting.It is mutually tied for fever and chills, damp and hot middle resistance, feeling of fullness Vomiting.Cornel coptis is relaxed liver anti-vomiting.For liver-stomach disharmony, acid regurgitation is vomitted.Pharmacological action:1st, antibacterial action 2, antimycotic work With 3, antivirus action 4, anti-amoeba effect 5, anti-inflammatory, anti-CaM antibody 6., to Cardiovascular 7, refrigeration function 8, Hypoglycemic effect 9, effect for reducing blood fat 10, antioxidation 11, the influence 12 to hematological system, anti-ulcer effect.
The root bark of Chinese wolf-berry:Chemical composition:Root skin contains glycine betaine(betaine), lyciumamide(lyciumamide), cupreol, Cryptojaponol(sugiol), Melissic Acid(melissic acid), linoleic acid and cinnamic acid.Nature and flavor:It is cold in nature, it is sweet in flavor.Major function: Cool blood is except steaming, clearing lung-heat fall fire.For deficiency of Yin hectic fever, hectic fever due to yin night sweat, cough with lung heat, spitting of blood, bleeding from five sense organs or subcutaneous tissue.
Radix Astragali:With 1, exterior deficiency spontaneous perspiration, it is chiefly used in the weak caused spontaneous perspiration of physically weak table.2nd, night sweat due to yin deficiency;3rd, acute nephritis water It is swollen, for the void oedema caused by YANG QI deficiency;4th, oedema due to chronic nephritis, spleen kidney deficiency person;5th, yang-energy is weak, long for sore Not diabrosis and invaginate, have promote diabrosis and limitation effect.6th, sore bursts be not cured long, after sore diabrosis, does not close up long, there is life The effect of flesh closing in;7th, syndrome of deficiency of spleen qi, weak burnout, diarrhea, the sinking of qi of middle-jiao, internal organs prolapsus, the indigestion and loss of appetite all diseases of deficiency of food.8th, Lung Qi deficiency Card.With the passing of time, shortness of breath and tired spirit, phlegm harmony is brought up in lung is powerless cough and asthma.9th, hidrosis and edema.10th, it is weak for the deficiency of vital energy, lassitude hypodynamia, Or the sinking of qi of middle-jiao, rectal prolapse, the prolapse of uterus.Nature and flavor:It is sweet, tepor.Channel tropism:Return lung, spleen, liver and kidney channel;There is enhancing immunity of organism work( Energy, liver protection, diuresis, anti-aging, resisting stress, decompression and wide antibacterial action.
Pueraria lobata:With fitness, anti-aging, decompression, hypoglycemic, lipid-loweringing, increase skin elasticity, moisturizing and other effects.Pueraria lobata Middle institute's isoflavone-containing has the function of to moisturize the skin, restores skin elasticity, can also slow down the aging of skeletal tissue's cell, help In calcareous absorption, reduce bone calcium and lose, increase bone density and prevent bone it is hollow disappear it is molten, so as to far from osteoporosis.Pueraria lobota Active constituent in root can prevent cardio-cerebrovascular diseases and effectively alleviate climacteric syndrome, and can promote longevity, increase Into health, the ideal chose for be female middle-aged daily health caring, improving the quality of living.Most it will be appreciated that women often eats pueraria lobata, Breast development can be promoted to increase, this is exactly mainly the contribution of isoflavones.Chemical composition:The pueraria lobata of the main isoflavone-containing class of pueraria lobata The ingredients such as element and triterpenes Pueraria lobota soap alcohol.
Radix Salviae Miltiorrhizae:Mildly bitter flavor, cold nature.Color is red, enters the heart channel of Hang-Shaoyin.Bushing, green blood, nourishing heart, sedate, calming heart and tranquilizing mind, forgetful palpitation, Palpitation with fear is insomnia, and raw new blood removes hemostasis, peaceful tire falls stillborn foetus.For sternal rib hypochondriac pain, arthralgia pain due to rheumatism, abdominal mass caking, sore swell and ache curative, It is grieved to fall servant, irregular menstruation, closed dysmenorrhea, postpartum stasis caused pain etc..Treat sternal rib pain, abdominal mass caking and irregular menstruation, Amenorrhea Dysmenorrhoea has good effect.
Fructus Forsythiae:【Chemical composition】Fruit is containing forsythol, sterol compound, saponin(Without hemolytic)And Flavonoids, horse Tongue resinol glucoside etc..Antibacterial action weeping forsythia concentrated decoction has antibacterial action in vitro, can inhibit typhoid bacillus, paratyphosum Bacterium, Escherichia coli, shigella dysenteriae, corynebacterium diphtheriae and comma bacillus, staphylococcus, streptococcus etc..【Function cures mainly】It is clearing heat and detoxicating, disappear Swollen dissipating bind, dispelling wind and heat from the body have the title of " persons particularly liable to develop skin infection's panacea ".Control warm, erysipelas, macula, large carbuncle pyogenic infections, scrofula, urine leaching closes clear away heart-fire Fire.
Cortex Magnoliae Officinalis:【Nature and flavor】:It is bitter;It is pungent;It is warm-natured【Channel tropism】:The spleen channel;Stomach;Large intestine channel.【Function】:Gas consumption product;Eliminating dampness is removed It is full;Relieving asthma【It cures mainly】:Stagnation of QI due to dyspepsia;Abdominal distention constipation;Damp retention in middle-jiao, abdominal swelling and diarrhea;Phlegm stops up the circulation of vital energy in the wrong direction;Chest full of cough.
Betel nut:Chemical composition:Seed contain a variety of alkaloids, content about 0.3~0.7%, based on arecaline, at normal temperatures It is the active ingredient of expelling parasite for oily liquids.Other is crystallobionts alkali:Such as arecaidine, arecolidine, demethyl betel nut Secondary alkali, guvacolines, mostly invalid components.In addition, still containing tannin about 15%, fat oil 14~18%, haematochrome(Betel nut It is red), leucocyanidin, a small amount of protein, volatile oil, choline and natural gum etc..It cures mainly:1st, abdominal pain due to enterositosis.2nd, stagnate diarrhea. 3rd, the full betel nut of tinea pedis asthma, which is also commonly used, controls tinea pedis oedema, and pain, then asthma is full long, it is impossible to the cards such as lie down.
Selfheal:【Meridian distribution of property and flavor】:It is cold;It is bitter, pungent;Return liver, gallbladder channel.【Major function】:It relieves inflammation or internal heat, improving eyesight, dissipating bind, detumescence. For red eye, swell pain, mesh pearl nyctalgia, dizziness of having a headache, scrofula, goiter and tumor, swelling and pain;Thyroid Gland Swell, scrofula, the proliferation of mammary gland, Hypertension, hyperglycemia, hyperlipidemia and high blood glue.
Lycopodium calvatum:Meridian distribution of property and flavor toil temperature, enters Liver Channel.Expelling wind and clearing away cold dehumidification swellings, relaxing tendons and activating collaterals.It is wet for chill Numbness, muscle arteries and veins contraction pain carbuncle.Bruises and spasms are controlled in external application.
Scorpio:Have the function of " antispastic cramp and relieves dizziness, is removed obstruction in channels to relieve pain at anti-inflammatory and attacked poison ";Cure mainly " child convulsion, twitch spasm, skin The diseases such as skin disease, cardiovascular and cerebrovascular diseases, inflammation, hepatitis B, tumour ".Scorpio is full of nutrition, prevents and cures diseases, strengthen immunity and anti-ageing It waits for a long time function.
Raw medicinal material pharmacological property effect selected by the present invention is complementary, evaded the mutual inhibition of compatibility between drug, mutual restraint between two drugs, the mutual-detoxication it The effect of choosing, makes drug mutual reinforcement between, mutually makes effect notable, has and improves immunity, Yin-nourishing and body fluid promoting, clearing heat and cooling blood.Orally taken for curing sugar Urine disease, has definite curative effect.
Using of the present invention for treating diabetes innerwear Chinese medicine preparation, by clinical practice, achieve unexpected Promising result;
Drug treatment of diabetic clinical observation of the present invention:
1. general information
Accept out-patient totally 23 for medical treatment, 20 ~ 30 years old age 6,31 ~ 40 years old 6,41 ~ 50 years old 7,50 years old or more 4.
It is as follows that 2. case is embodied:Man, 65 years old, Han nationality.【Main suit】Thirsty, more drinks, diuresis January, fever is with bleb 2 My god.【Medical history】Because of, without apparent inducement, right chest shouting pain was felt before 2 days, there is item in the wall of the chest and pleurobranch wall before checking on the right side of discovery The large area bleb of shape distribution, in shape is clustered round, self-induction is weak, does not examine just now.It checks and finds T37.5 DEG C, question closely medical history, Huan Zheyou Thirsty, more drinks, diuresis are more than January, no weight loss.Next day has a blood test sugar:Fasting blood-glucose:16.5mmol/L 2h-plasma glucose:25.6 mmol/L.Since patient's idiopathy, spirit can, be slept poor;Two is just normal.Previously deny diabetic history, cardiovascular and cerebrovascular diseases History, history of hypertension 3 years.Without hepatitis, tuberculosis medical history, medicine-less allergy history.Being born in local, no venereal disease, no tobacco and wine etc., other are special Bad life hobby, no family's heredity medication history.With 15 doses of prescription of the present invention is thrown, 1 dose is taken daily, divides 2 times sooner or later and warmly takes, on an empty stomach Boiling water is taken after mixing it with water.With examining later, all diseases mitigate.30 courses for the treatment of of following the service, all diseases are all removed.It is enjoined, one course for the treatment of of continual cure, which is consolidated, to be treated Effect.Take several doses i.e. more.
Specific embodiment
It is described to be used to treat diabetes innerwear Chinese medicine preparation, which is characterized in that Chinese medicine material and the parts by weight difference of selection It is:30 grams of spina date seed, 25 grams of the seed of Oriental arborvitae, 25 grams of Radix Ophiopogonis, 25 grams of Schisandra chinensis, 30 grams of the fruit of Chinese wolfberry, 20 grams of ginseng, 15 grams of radix rehmanniae recen, 15 grams of the coptis, 18 grams of the root bark of Chinese wolf-berry, 20 grams of Radix Astragali, 25 grams of pueraria lobata, 20 grams of Radix Salviae Miltiorrhizae, 19 grams of Fructus Forsythiae, 10 grams of Cortex Magnoliae Officinalis, 20 grams of betel nut, summer 20 grams of withered grass, 23 grams of lycopodium calvatum, 18 grams of scorpio;
Preparation method:30 grams of spina date seed, 25 grams of the seed of Oriental arborvitae, 25 grams of Radix Ophiopogonis, 25 grams of Schisandra chinensis, 30 grams of the fruit of Chinese wolfberry, 20 grams of ginseng, life 15 grams of glutinous rehmannia, 15 grams of the coptis, 18 grams of the root bark of Chinese wolf-berry, 20 grams of Radix Astragali, 25 grams of pueraria lobata, 20 grams of Radix Salviae Miltiorrhizae, 19 grams of Fructus Forsythiae, 10 grams of Cortex Magnoliae Officinalis, Bin Bulky 20 grams, 20 grams of selfheal, 23 grams of lycopodium calvatum, 18 grams of scorpio;Medicine materical crude slice is respectively prepared, divides by pressure cooker cooking disinfection 50-70 Clock dries, and obtains aseptic raw material, is sealed packaging, obtains commodity Chinese medicine preparation drink.

Claims (2)

1. for treating diabetes innerwear Chinese medicine preparation, which is characterized in that the Chinese medicine material and parts by weight of selection be respectively:Wild jujube 30 grams of benevolence, 25 grams of the seed of Oriental arborvitae, 25 grams of Radix Ophiopogonis, 25 grams of Schisandra chinensis, 30 grams of the fruit of Chinese wolfberry, 20 grams of ginseng, 15 grams of radix rehmanniae recen, the coptis 15 Gram, 18 grams of the root bark of Chinese wolf-berry, 20 grams of Radix Astragali, 25 grams of pueraria lobata, 20 grams of Radix Salviae Miltiorrhizae, 19 grams of Fructus Forsythiae, 10 grams of Cortex Magnoliae Officinalis, 20 grams of betel nut, selfheal 20 Gram, 23 grams of lycopodium calvatum, 18 grams of scorpio.
2. treatment diabetes innerwear Chinese medicine preparation according to claim 1, it is characterised in that:Preparation method is following step Suddenly:Step 1)Weigh raw medicinal material:30 grams of spina date seed, 25 grams of the seed of Oriental arborvitae, 25 grams of Radix Ophiopogonis, 25 grams of Schisandra chinensis, 30 grams of the fruit of Chinese wolfberry, 20 grams of ginseng, 15 grams of radix rehmanniae recen, 15 grams of the coptis, 18 grams of the root bark of Chinese wolf-berry, 20 grams of Radix Astragali, 25 grams of pueraria lobata, 20 grams of Radix Salviae Miltiorrhizae, 19 grams of Fructus Forsythiae, 10 grams of Cortex Magnoliae Officinalis, 20 grams of betel nut, 20 grams of selfheal, 23 grams of lycopodium calvatum, 18 grams of scorpio;
Step 2:The medicine materical crude slice that will be obtained by pressure cooker cooking disinfection 50-70 minutes, dries, and obtains aseptic raw material;
Step 3:The aseptic raw material that will be obtained is sealed packaging, obtains commodity Chinese medicine preparation drink.
CN201611209866.9A 2016-12-24 2016-12-24 It quenches one's thirst mind-tranquilizing formulation Pending CN108236667A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1255358A (en) * 1999-07-31 2000-06-07 唐淑杰 Chinese medicine for treating diabetes
CN101934030A (en) * 2010-08-28 2011-01-05 郑沛 Medicinal composition for treating symptom-complex of excessive eating (diabetes) and method for preparing same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1255358A (en) * 1999-07-31 2000-06-07 唐淑杰 Chinese medicine for treating diabetes
CN101934030A (en) * 2010-08-28 2011-01-05 郑沛 Medicinal composition for treating symptom-complex of excessive eating (diabetes) and method for preparing same

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
姜兆顺等: "自拟三黄杞丹汤加减辅助治疗糖尿病肾病", 《实用医药杂志》 *
崔燕等: "中药降糖液超声雾化导入治疗糖尿病疗效观察", 《中国中医药信息杂志》 *
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