CN104306906A

CN104306906A - Lotus leaf diet tea for obese people and preparing method of lotus leaf diet tea

Info

Publication number: CN104306906A
Application number: CN201410681824.XA
Authority: CN
Inventors: 不公告发明人
Original assignee: Qingdao Hengbo Instrument Co Ltd
Current assignee: Qingdao Hengbo Instrument Co Ltd
Priority date: 2014-11-24
Filing date: 2014-11-24
Publication date: 2015-01-28

Abstract

The invention provides lotus leaf diet tea for obese people. The lotus leaf diet tea is composed of, by weight, 10-50 parts of lotus leaves, 10-20 parts of pericarpium citri reticulatae, 10-20 parts of hawthorn, 10-20 parts of sealwort, 10-20 parts of coix seeds, 10-20 parts of curcuma zedoary, 10-20 parts of poria cocos, 10-20 parts of rehmannia roots, 10-20 parts of rhizoma cyperi, 10-20 parts of rhizoma atractylodis macrocephalae, 10-20 parts of red-rooted salvia roots, 10-20 parts of common peony roots, 10-20 parts of lalang grass rhizome, 10-20 parts of rhizoma atractylodis and 10-20 parts of parasitic loranthus. The experiment on the function test and toxicology shows that the lotus leaf diet tea can promote fat metabolism and lipolysis, make normal physiological functions maintained and overcome the defects that the diet rule is broken by weight-losing products such as good replacing type weight-losing products, excretion type weight-losing products and neural inhibition type weight-losing products, the functions of a human body are reduced and other diseases are caused, and therefore the lotus leaf diet tea is highly appreciated by obese people. The lotus leaf diet tea is dark green in soup color, rich in fragrance and slightly bitter but sweet; by adding some traditional Chinese medicine having the remarkable effects on promoting blood circulation to remove blood stasis and reducing fat and serum triglyceride, the lotus leaf diet tea can improve microcirculation and can be easily accepted by people so that the weight losing function can be achieved.

Description

A kind of Folium Nelumbinis for obese people is lost weight and preparation method thereof

Technical field

The present invention relates to the slimming health product containing deriving from plant composition, particularly a kind of Folium Nelumbinis for obese people is lost weight and preparation method thereof.

Background technology

Obesity refers to that health contains excess fat tissue, and the fat content generally in woman's health is above standard body weight 10%, and man, more than 20% ~ 25%, can confirm as obesity.World Health Organization (WHO) (WHO) proposes fat neodoxy: obesity be a kind of with body fat content too much for key character, multi-pathogenesis, can the chronic disease of concurrent various diseases.

1999, WHO announced that obesity is a kind of disease, and second lethal risk factor that can prevent after being only second to smoking, be listed as worldwide four large medical science societies with acquired immune deficiency syndrome (AIDS), drug abuse, excessive drinking and ask Lie 21.According to a investigation report display that PAHO announces a few days ago, in the U.S., the adult of 1/3rd suffers from obesity.In Canada, the population of suffering from obesity accounts for 13%.Also there is similar phenomenon in Argentina, Colombia, Mexico, Germany, Finland, Jamaica, Kuwait and Czech: the population considered overweight of at least 50%, and the people of more than 15% suffers from obesity.It is 22.8% that Chinese residents nutrition in 2002 and Health Situation survey result show China's overweight rate of being grown up, and obesity rates is 7.1%, and number to be respectively more than 200,000,000 and 6,000 ten thousand.Overweight rate and obesity rates are grown up respectively up to 30.0% and 12.3% in big city.Compared with 1992, overweight rising 39% of being grown up, obesity rates rises 97%.

The public health problem that fat of also having become that China faces is serious.Obesity not only affects figure and activity, usual obese patient is with abnormalities of sugar/lipid metabolism, insulin resistant and hyperlipidemia, hypertension, raise with hypertriglyceridemia, low density lipoprotein, LDL (LDL) and high density lipoprotein (HDL) is reduced to feature.Hyperlipemia is by acting on mesangial cell and the release inflammation factor, make glomerular sclerosis, simultaneously, lipid can make glomerular endothelial cells dysfunction again, cause glomerule fibrosis: because the accumulation of fat can cause insulin resistant, hyperinsulinemia, muscle and its hetero-organization reduce the utilization of glucose, then develop into sugar tolerance and successively decrease, finally develop into diabetes;

Usually there is restrictive ventilatory functional disturbance and insufficiency of accommodation in obese patient, respiratory frequency is caused to be accelerated, thus cause obesity-related asthma: because people are considered as obesity unsightly usually, seldom facing obesity is a kind of disease, thus causes fat patient often with mental illness such as fat obsession, anorexia nervosa and depressions; In addition, obesity can also cause sleep-apnea, fatty liver, cholelithiasis, brain soldier, osteoarthritis, cancer etc.

In numerous appetrol, U.S. FDA only ratifies two kinds of medicines can life-time service: sibutramine (Sibutmmine) and orlistat (Orlistat), these two kinds of medicines have different mechanism of action, while indicating that it has different pharmacological propertieses, also create different side effect performances.Sibutramine is the main component of the appetrol swept the country at present, its mechanism of action reduces things intake by increasing satiety and increase energy expenditure by stimulation heat production, he can directly act on central nervous system, so its impact is system, he directly can affect hypothalamus, suppress it to the picked-up of norepinephrine and dopamine etc., thus cause anorexia, and hypothalamus is endocrine hormone maincenter, on hold central nervous system, under connect hypophysis and every other hormone target tissue, therefore, the clinical common untoward reaction of sibutramine comprises the depression and mania etc. of spiritual aspect, also comprise the arrhythmia of cardiovascular aspect, cardiopalmus and chest pain, serious have asystolic room to quiver and the clinical report such as myocardial infarction.Orlistat commodity plug by name Buddhist nun can, mechanism of action suppresses harmonization of the stomach pancreatic lipase and stops dietary fat to be converted into Absorbable rod form, and then the absorption of dietary fat can be prevented, but also affect the absorption of soluble lipids vitamin simultaneously, common untoward reaction also has intestinal symptom, there are the increase of fats/oils feces, times of defecation, vexed oil, rare stool, stomachache, defecation rapid, flatulence, urinary incontinence and oil excretion, in addition, orlistat is that nearest 2-3 just gets the Green Light use, and its long-term effect need inspection.The Western medicine of other treatment obesity also has fenfluramine, phenylpropanolamine etc., but because of its side effect strong, untoward reaction is many, is scarcely suitable for life-time service or has prohibitted the use.

The Chinese traditional treatment obesity history of existing more than 2,000 year, in the classical literature " (Huang di's Canon of Medicine " of motherland's medical science, just has the relevant discussion about obesity.The method of Chinese traditional treatment obesity is also a lot, mainly contains internal treatment and external treatment.Internal treatment determines pattern of syndrome according to differentiation of tcm, or coordinates medicated diet, dietetic therapy etc.External treatment has acupuncture, ear note, scrape therapy, stifling, the qigong, massage etc.In recent years, Chinese medicine had carried out extensive and deep research to obesity, also achieved larger progress.Again because the side effect of Chinese traditional treatment obesity is little, rebound rate is low, is more and more subject to the attention of Chinese scholars.Japan often uses FANGFENG TOGSHENG SAN, Radix Stephaniae Tetrandrae Radix Rehmanniae soup, dachaihu decoction, DACHENGQI TANG, Semen Juglandis CHENGQI TANG etc., and for various pattern of syndrome, symptom is improved significantly, and therapeutic effect is obvious.

" (Compendium of Materia Medica ", " (occupy diet spectrum with breath ", " (Chinese herb tea formula is complete works of " etc. at all times medicine (food) learn ancient books and records and think: Plumula Nelumbinis and Folium Nelumbinis have clearing away heart-fire, suppressing the hyperactive liver fire, purgation of spleen excess fiery, lung-fire falls and heat clearing away is reposed, antihypertensive diuretic, hold back liquid hidroschesis, effects such as controlling nocturnal emission with astringent drugs of stopping blooding." Folium Nelumbinis is lost weight, and makes us thin bad ", China just regards as Folium Nelumbinis the good medicine of weight reducing since ancient times.In hospital, adiposis patient is still allowed to drink Folium Nelumbinis tea.Containing multiple effectiveization fat alkaloid in nuciferine in Folium Nelumbinis tea, can fat effectively in decomposer, and powerfully to excrete.On the intrepid densely covered human body intestinal wall of nuciferine energy, form one deck fat isolating membrane, stop fat absorption, prevent athero.Can improve greasy dietary habit, it has stronger oils and fats and repels effect thus allow you gradually produce dislike to meat or fish stodge.So have the Antilipemic health effect of outstanding effect of weight reducing and brilliance.

1. promote intestinal peristalsis promoting, discharge toxin

Containing a large amount of fiber in Folium Nelumbinis tea, can intestinal peristalsis be impelled, help defecation thus can toxin be removed.Folium Nelumbinis tea more has convenient effect than general high fine food, directly solves the worry of constipation, and the lower abdomen therefore swelled will become smooth at leisure.

2. draining diuresis, strong urine disappears fat

Aromatic compound in Folium Nelumbinis tea can effective dissolved fat, changes turbid going and greasyly prevents in the stagnant body of fat; Vitamin B1, C and caffeine can promote gastric secretion, have aid digestion with the fat that disappears.For confirmed fatigue pressure gang, drink how dynamic but how all thin Qi-stagnation type do not got off fat anslim flowers and plants Isohexadecane, in Folium Nelumbinis etc., more can play dual slimming effect less.Also have splendid diuretic effect, working clan, easily edema that sitting is moved less, the MM of insufficiency of the spleen, the deficiency of vital energy, will drink Folium Nelumbinis tea, when fat unnecessary in body and retention electrolyte are discharged, people will reduce naturally more simultaneously.

3. be rich in tea leptin, promote metabolism

Tea leptin is the protein component that a kind of natural appetite and the energy balance regulate approach, does not add any insalubrious chemical composition, can not cause the side effect such as diarrhoea and stomachache.The disappearance of tea leptin can suppress metabolism, reduces efficiency of power dissipation, causes fat.And drink Folium Nelumbinis tea and can supplement the tea leptin that human body consumes at intestinal, body metabolism can be improved, allow you become easy lean body mass.

The traditional Chinese medical science one is to good medicine Folium Nelumbinis being regarded as fat-reducing.Increasing people starts with the health tea of Folium Nelumbinis tea as daily weight reducing, Folium Nelumbinis tea mainly has and reduces fat, eliminates constipation, diuresis three kinds effect, by the women that obesity perplexs, and because considering the people preventing adult diseases to the middle age, there is no harm in some Folium Nelumbinis tea of polydipsia, long-term drink is also free from side effects to health.In addition, another large class active substance--alkaloid in Folium Nelumbinis, physiologically active is remarkable, has the effects such as obvious blood fat reducing, antiviral.

China just regards as Folium Nelumbinis the good medicine of weight reducing since ancient times.Because the root of Flos Nelumbinis, Rhizoma Nelumbinis and leaf have the effect of simple diuresis, relieving constipation.Make full use of the fat-reducing effect of Folium Nelumbinis tea, Folium Nelumbinis, refrigerantly to relieve inflammation or internal heat, disappear fat intestine moistening, and a lot of people knows and drinks Folium Nelumbinis tea to lose weight.The effect that the flower of Flos Nelumbinis, leaf, fruit have in the record of Chinese medicine Book of Records " make light of one's life by commiting suicide, carburetion ", not only can oils and fats in removing body, can also improve complexion, as far back as the Ming Dynasty, just have the record of " Folium Nelumbinis uplifting yang qi, degrease are reduced weight " in Compendium of Material Medica.After drinking a period of time, meeting nature becomes not to be liked to eat greasy food, and the crowd too much to picked-up lubricant component is the most applicable.

Folium Nelumbinis is the blade of aquatic herbaceous plant lotus for many years, and its chemical composition mainly contains the alkaline components of nuciferine, citric acid, malic acid, gluconic acid, oxalic acid, succinic acid and other resisting mitosis effect.Pharmacological research finds, Folium Nelumbinis has antipyretic, antibacterial, spasmolysis.Folium Nelumbinis bitter and puckery flavor, micro-one-tenth after concocting, property is pungent cool, has clearing away summer-heat and eliminating dampness, an effect such as yang invigorating is dispersed, hemostasis by removing blood stasis, to various disease conditions all have certain curative effect therefore Folium Nelumbinis tea there is certain antiobesity action.The preserved material of Folium Nelumbinis and the more expansible blood vessel of decoct, clearing away summer-heat, has the effect of blood pressure lowering, the good medicine of still fat-reducing simultaneously.Folium Nelumbinis tea obviously can also reduce triglyceride and cholesterol level in serum, has the health-care effect of adjusting blood lipid.

Medical verification, Folium Nelumbinis tea can blood fat reducing, has antiobesity action, cleaning the intestines and stomach, eliminating toxin and beautifying the skin, liver nourishing lung moistening, lotus leaf health-care tea have passed function assessment and toxicological experiment proves, lipid metabolism and decomposition can be promoted, maintain normal physiological function, overcome for food type, excretion pattern, the diet products such as neural suppressive destroy dietary, reduce function of human body, and bring out the shortcoming of Other diseases, therefore Folium Nelumbinis tea fat-reducing is subject to the vast favor of obese people.

Along with industrialized development, the change of dietary structure, the improvement of living condition, the fat killer more and more becoming present people's health.Become global and have a strong impact on healthy epidemic diseases, somebody can seem forever can not subtract, drink cold water and all put on flesh.Therefore, search of health effective Weight-reducing and lipid-lowering method has very real significance.Weight-reducing active substance is the key that people expect to deal with problems always safely and effectively.Weight-reducing and lipid-lowering method is a lot, has dietetic therapy, exercise therapy, pharmacotherapy and clinical treatment etc.These methods more or less have weak point, and what have also easily causes side effect, as diarrhoea, anorexia etc.In recent years, Chinese medicine had carried out extensive and deep research to obesity, also achieved larger progress.Again because the side effect of Chinese traditional treatment obesity is little, rebound rate is low, is more and more subject to the attention of Chinese scholars.

Summary of the invention

Technical problem to be solved by this invention is, the fat Western medicine for the treatment of has fenfluramine, phenylpropanolamine etc., but because of its side effect strong, untoward reaction is many, is scarcely suitable for life-time service or has prohibitted the use.Chinese medicine has carried out extensive and deep research to obesity, also achieves larger progress.Again because the side effect of Chinese traditional treatment obesity is little, rebound rate is low, is more and more subject to the attention of Chinese scholars.Traditional Chinese medicine capable of reducing weight blood fat reducing, having advantage that is nontoxic, that can be absorbed completely by organism, is the Main way that we study.

Lotus leaf health-care tea have passed function assessment and toxicological experiment proves, lipid metabolism and decomposition can be promoted, maintain normal physiological function, overcome for food type, excretion pattern, the diet products such as neural suppressive destroy dietary, reduce function of human body, and bring out the shortcoming of Other diseases, therefore Folium Nelumbinis tea fat-reducing is subject to the favor of obese people.Soup color of the present invention is dark green, and delicate fragrance overflows, micro-bitter glycol; Add some blood circulation promoting and blood stasis dispelling, fat and serum triglycerides are all had to the Chinese crude drug of obvious reducing effect, and can microcirculation be improved, make people be easy to accept, reach the function of fat-reducing, more can reach effect of hypoglycemic preferably.

For solving above-mentioned technical barrier, the invention provides a kind of Folium Nelumbinis diet tea for obese people, the parts by weight of the various raw materials of diet tea described in it can be: 10 ~ 50 parts, Folium Nelumbinis, Pericarpium Citri Reticulatae 10 ~ 20 parts, Fructus Crataegi 10 ~ 20 parts, Rhizoma Polygonati 10 ~ 20 parts, Semen Coicis 10 ~ 20 parts, Rhizoma Curcumae 10 ~ 20 parts, 10 ~ 20 parts, Poria, 10 ~ 20 parts, the Radix Rehmanniae, Rhizoma Cyperi 10 ~ 20 parts, the Rhizoma Atractylodis Macrocephalae 10 ~ 20 parts, Radix Salviae Miltiorrhizae 10 ~ 20 parts, Radix Paeoniae Rubra 10 ~ 20 parts, Rhizoma Imperatae 10 ~ 20 parts, Rhizoma Atractylodis 10 ~ 20 parts, Herba Taxilli 10 ~ 20 parts.

Described a kind of Folium Nelumbinis diet tea for obese people, the parts by weight of the various raw materials of diet tea described in it can also be: 10 ~ 40 parts, Folium Nelumbinis, Pericarpium Citri Reticulatae 10 ~ 15 parts, Fructus Crataegi 10 ~ 15 parts, Rhizoma Polygonati 10 ~ 15 parts, Semen Coicis 10 ~ 15 parts, Rhizoma Curcumae 10 ~ 15 parts, 10 ~ 15 parts, Poria, 10 ~ 15 parts, the Radix Rehmanniae, Rhizoma Cyperi 10 ~ 20 parts, the Rhizoma Atractylodis Macrocephalae 10 ~ 20 parts, Radix Salviae Miltiorrhizae 10 ~ 20 parts, Radix Paeoniae Rubra 10 ~ 20 parts, Rhizoma Imperatae 10 ~ 20 parts, Rhizoma Atractylodis 10 ~ 20 parts, Herba Taxilli 10 ~ 20 parts.

Described a kind of Folium Nelumbinis diet tea for obese people, the parts by weight of the various raw materials of diet tea described in it also can be: 10 ~ 30 parts, Folium Nelumbinis, Pericarpium Citri Reticulatae 10 ~ 20 parts, Fructus Crataegi 10 ~ 20 parts, Rhizoma Polygonati 10 ~ 20 parts, Semen Coicis 10 ~ 20 parts, Rhizoma Curcumae 10 ~ 20 parts, 10 ~ 20 parts, Poria, 10 ~ 20 parts, the Radix Rehmanniae, Rhizoma Cyperi 10 ~ 15 parts, the Rhizoma Atractylodis Macrocephalae 10 ~ 15 parts, Radix Salviae Miltiorrhizae 10 ~ 15 parts, Radix Paeoniae Rubra 10 ~ 15 parts, Rhizoma Imperatae 10 ~ 15 parts, Rhizoma Atractylodis 10 ~ 15 parts, Herba Taxilli 10 ~ 15 parts.

For solving the problems of the technologies described above, the present invention also provides a kind of preparation method of the Folium Nelumbinis diet tea for obese people, and described in it, the preparation process of diet tea comprises following aspect:

A. the preparation of Folium Nelumbinis;

B. by other raw material pulverizing described, immersion, heating, reflux, extract, 2 times;

C. again the concentration of liquid medicine that surplus stock extracts is become granule, powder or unguentum;

D. concentrated granule, powder or unguentum are mixed with the Folium Nelumbinis prepared, be prepared into health tea.

In described step a, can gather at 6 ~ JIUYUE summer Qiu Erji, removing petiole, is cleaned the slice being cut into 2-4cm, shines to seven, most probably does, put aeration-drying place, mothproof.

In described step b, by all the other crude drug roguings, can dry, be ground into granule, soak 1 hour; Soaked raw material is put in multi-function extractor and decocts with water secondary; Add up the water of medical material 10 times amount for the first time, decoct 1.5 ~ 2 hours, get decocting liquid, filter; Second time adds the water of total amount 7 times amount, decocts 1 ~ 1.2 hour, gets twice decocting liquid mixing, filters; Heating is concentrated into pasty state filtrate, stand for standby use.

In described step c, the filtrate of filtration can be inserted in economic benefits and social benefits vacuum concentrator, when being concentrated into 90 DEG C, relative density is the concentrated solution of 1.05, sets to 0 ~ 5 DEG C of deepfreezes 24 hours; Cold preservation liquid is added the filter aid kieselguhr of 0.3%, filter, filtrate is inserted in economic benefits and social benefits vacuum concentrator again, is concentrated into every 1ml containing 1g crude drug amount, convection drying powdered, or adds dextrin and make granule.

In described steps d, the powder Folium Nelumbinis prepared and surplus stock can prepared or granule mix, and ultraviolet disinfection is packed and be get final product.

For solving the problems of the technologies described above, the present invention reoffers a kind of preparation method of the Folium Nelumbinis diet tea for obese people, and when granule made by other raw materials of described health tea, step can also be:

A, get other raw materials and put into ethanol and soak, heat is carried, and is component 1;

B, by medicinal residues extracting in water 2 times, thickening filtration is component 2;

C, by 2-in-1 and concentrated to component 1 and component; Lixiviate.

10, according to claim 9 for the preparation method of the Folium Nelumbinis diet tea of obese people, it is characterized in that: in described step a, get raw material and add in the ethanol of 5-10 times amount and soak 1-2 hour, then put into extraction pot heated and boiled 1 hour, filter, filtrate is for subsequent use; For component 1; In described step b, filtering residue adds water, and second time heating, boils 45 minutes, and filter, filtrate is for subsequent use; Filtering residue adds water again, heated and boiled half an hour third time, filters; For component 2; In described step c, three filtrates be combined, by filtered through gauze, add 50-60% ethanol in residue, 60 DEG C-70 DEG C are continued lixiviate 2h, and every 10min stirs once, filtered through gauze, merge lixiviating solution, are condensed into pasty state and add Mel and put into granulator and granulate dry.

The technique effect that the present invention is useful is: Folium Nelumbinis is bitter and puckery flavor, micro-one-tenth after concocting, and property is put down, and has clearing away summer-heat and eliminating dampness, an effect such as yang invigorating is dispersed, hemostasis by removing blood stasis, all has certain curative effect to various disease conditions.Medical verification, Folium Nelumbinis tea can blood fat reducing, has antiobesity action, cleaning the intestines and stomach, eliminating toxin and beautifying the skin, liver nourishing lung moistening, Folium Nelumbinis diet tea have passed function assessment and toxicological experiment proves, lipid metabolism and decomposition can be promoted, maintain normal physiological function, overcome for food type, excretion pattern, the diet products such as neural suppressive destroy dietary, reduce function of human body, and bring out the shortcoming of Other diseases, therefore Folium Nelumbinis tea diet tea is subject to the favor of obese people.Soup color of the present invention is dark green, and delicate fragrance overflows, micro-bitter glycol; Add some blood circulation promoting and blood stasis dispelling, fat and serum triglycerides are all had to the Chinese crude drug of obvious reducing effect, and can microcirculation be improved, make people be easy to accept, reach the function of fat-reducing.

Detailed description of the invention

One of modal obesity of simple obesity, its essence is that body fat absolute magnitude increases, but without obvious endocrine, the metabolic disease cause of disease can be sought, and it is the risk factor of multiple serious harm health disease (as diabetes, coronary atherosclerotic heart disease, cerebrovascular disease, hypertension, hyperlipemia etc.).According to estimates, overweight (comprising obesity) person has 1,300,000,000 at least in the world.Account for 3/5ths of total population U.S. obesity patient, cause annual 30 people She ten thousand dead; European countries' prevalence is generally about 20%; And more than the super severe one of China more than 20 years old about 2.4 hundred million people, obesity patient can reach more than 30,000,000 people.Current World Health Organization (WHO) (WHO) has confirmed obesity to be classified as one of primary health problem in the whole world, and its control tool is of great significance.

The patient of the serious diseases such as the coronary heart disease caused by obesity, hyperlipidemia constantly increases, and has researched and proposed new requirement thus to associated treatment medicine, and the drug research in blood fat reducing, fat-reducing and exploitation significantly increase.

Pungent micro-puckery, the property of Folium Nelumbinis bitter in the mouth is put down, GUIXIN, liver, spleen channel; Delicate fragrance rises loose; There is summer heat relieving and dampness eliminating, spleen invigorating yang invigorating, effect of dissipating blood stasis hemostasis; Cure mainly summer-heat excessive thirst, have a headache dizzy, edema, lack of appetite abdominal distention, dysentery, leucorrhea, proctoptosis, spit blood, epistaxis, spitting of blood, has blood in stool, metrorrhagia, post partum longtime lochia, traumatic blood stasis.

Compendium of Material Medica, " occupying diet spectrum with breath ", " Chinese herb tea formula complete works of " etc. at all times medicine (food) are learned ancient books and records and are thought: Plumula Nelumbinis and Folium Nelumbinis have clearing away heart-fire, suppressing the hyperactive liver fire, purgation of spleen excess fiery, lung-fire falls and heat clearing away is reposed, antihypertensive diuretic, hold back liquid hidroschesis, effects such as controlling nocturnal emission with astringent drugs of stopping blooding." Folium Nelumbinis is lost weight, and makes us thin bad ", China just regards as Folium Nelumbinis the good medicine of weight reducing since ancient times.In hospital, adiposis patient is still allowed to drink Folium Nelumbinis tea.Containing multiple effectiveization fat alkaloid in nuciferine in Folium Nelumbinis tea, can fat effectively in decomposer, and powerfully to excrete.On the intrepid densely covered human body intestinal wall of nuciferine energy, form one deck fat isolating membrane, stop fat absorption, prevent athero.Can improve greasy dietary habit, it has stronger oils and fats and repels effect thus allow you gradually produce dislike to meat or fish stodge.So have the Antilipemic health effect of outstanding effect of weight reducing and brilliance.

Folium Nelumbinis tea mainly has and reduces fat, eliminates constipation, diuresis three kinds effect, the women that perplexs by obesity, and because considering the people preventing adult diseases to the middle age, there is no harm in some Folium Nelumbinis tea of polydipsia.Folium Nelumbinis tea is a kind of food, but not medicine class, therefore there is nontoxic, safe advantage.

In addition, Folium Nelumbinis tea need not be boiled; Boiled water brews.Preferably can boil in a covered pot over a slow fire 5 ~ 6 minutes, such Folium Camelliae sinensis can be denseer.Even if tea is cool, its effect also can not change, so drink after can icing summer, taste is better.

The traditional Chinese medical science regards as the good medicine of fat-reducing Folium Nelumbinis.Increasing people starts with the health tea of Folium Nelumbinis tea as daily weight reducing, Folium Nelumbinis tea mainly has and reduces fat, eliminates constipation, diuresis three kinds effect, by the women that obesity perplexs, and because considering the people preventing adult diseases to the middle age, there is no harm in some Folium Nelumbinis tea of polydipsia, long-term drink is also free from side effects to health.In addition, another large class active substance---alkaloid in Folium Nelumbinis, physiologically active is remarkable, has the effects such as obvious blood fat reducing, antiviral.

Medical verification, Folium Nelumbinis tea can blood fat reducing, has antiobesity action, cleaning the intestines and stomach, eliminating toxin and beautifying the skin, liver nourishing lung moistening, lotus leaf health-care tea have passed function assessment and toxicological experiment proves, lipid metabolism and decomposition can be promoted, maintain normal physiological function, overcome for food type, excretion pattern, the diet products such as neural suppressive destroy dietary, reduce function of human body, and bring out the shortcoming of Other diseases, therefore Folium Nelumbinis tea hypoglycemic is subject to the favor of vast three-hypers crowd.

Radix Salviae Miltiorrhizae is bitter, is slightly cold.GUIXIN, Liver Channel.Stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia.For costa sternales hypochondriac pain, rheumatic arthralgia, lump in the abdomen lumps, and skin infection swells and ache, and tumbling down is grieved, menoxenia, amenorrhea dysmenorrhea, puerperal stasis of blood pain etc.Treatment costa sternales pain, lump in the abdomen caking, and menoxenia, amenorrhea dysmenorrhoea have good effect." detailed outline " carries: Radix Salviae Miltiorrhizae, and by " the sensible opinion of married woman " cloud, SIWU TANG controls gynecopathy, pays no attention to antenatal puerperal, how many through water, all can be general, and only taste Radix Salviae Miltiorrhizae falls apart, and cures mainly identical with it.Lid Radix Salviae Miltiorrhizae can break stagnated blood, and mend fresh blood, peaceful tire, fall stillborn fetus, only metrorrhagia dysentery, regulating menstruation arteries and veins.Main Compositions of Radix Salviae Miltiorrhizae TANSHINONES has blood vessel dilating, improves circulation, removes the effects such as intravascular coagulation, has effect of invigorating blood circulation trace, and can promote that liver blood circulates, be beneficial to liver cell regeneration.

Rhizoma Atractylodis Macrocephalae bitter in the mouth, sweet, temperature.Return spleen, stomach warp.Cure mainly invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.The Rhizoma Atractylodis Macrocephalae has cytotoxicity to oncocyte, can reduce the rate of increase of oncocyte, lowers the aggressive of tumor tissue, improves the ability of body antitumor reaction.Rhizoma Atractylodis Macrocephalae volatile oil has inhibitory action to mice ehrlich carcinoma, lymphosarcoma ascitic type, the esophageal carcinoma (Ecal09), sarcoma 180 etc.Atractylodes lactone B lumbar injection is to the murine sarcoma people.Also remarkable inhibitory action is had." property of medicine opinion " carries it: monarch, and sweet in the mouth is pungent, nontoxic.Energy main large migratory arthralgia, for many years diarrhea due to disorder of qi, trusted subordinate's distending pain, the broken dyspepsia that disappears, appetizing, removes sputum, except cold and heat, lets out only.Interarea light is pleased, and preserves youthful looks, de-black.Swelling of harnessing the river is full, tells vomiting, cold type of pain in abdomen, vomits and diarrhoea incessantly, and insufficiency of stomach-QI cold-dysentery.

Cortex Mori is the root bark of moraceae plants Mulberry Morus alba L..Main product in Anhui, Henan, Zhejiang, Jiangsu, the ground such as Hunan.Effect: eliminating pathogen from the lung for relieving asthma, inducing diuresis to remove edema.For lung-heat cough with asthma, the edema of the face, the diseases such as dysuria." property of medicine opinion ": make, flat.Can control lung qi dyspnea with fullness of the chest, aqueous vapor edema, main wound is exhausted, dredging water passages, and disappear aqueous vapor, and asthenia exopathogenic heat is had a headache, interior tonifying for the deficiency." Japan hanako materia medica ": temperature, in tune, the therapeutic method to keep the adverse QI flowing downwards.Expectorant is quenched the thirst, sharp intestine and small intestine, appetizing, lower food, and kill abdomen and hide worm, only cholera is vomited and diarrhoea.

Rhizoma Polygonati is used as medicine with rhizome.There is boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney benefiting functions.Be used for the treatment of weakness of the spleen and stomach, fatigue and asthenia, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, asthenia of essence and blood, interior-heat such as to be quenched one's thirst the disease.Very effective in cure for diabetes.Stir-baked RHIZOMA POLYGONATI with yellow rice wine is also known as processing Rhizoma Polygonati.The person of being used as medicine is dried for clean Rhizoma Polygonati steams rear section with the adjuvant such as wine and Semen sojae atricolor.Have the merit of meridians of escaping concurrently.Rhizoma Polygonati has blood pressure lowering, blood sugar lowering, blood fat reducing, atherosclerosis, and slow down aging and the effect such as antibacterial, polygonatum polysaccharide has Immunestimulatory effect.For lung-dryness syndrome due to deficiency of YIN, the few expectorant of dry cough, and the chronic cough chronic cough etc. of YIN-deficiency of the lung and kidney.For weakness of the spleen and stomach.Both tonifying spleen-yin, again strengthening the spleen gas, obtain dizzy, soreness of the waist and knees for deficiency of kidney essence, early whitening of beard and hair and quenching one's thirst.Rhizoma Polygonati strengthening bone and muscle, beneficial marrow, bleaches and sends out; The cough expectorant be suitable for caused by lack of lung-YIN is few, dry cough without phlegm, the diseases such as hemoptysis.

Poria sweet in the mouth, light, property are put down, and are used as medicine and have the function of promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Modern medicine study: Poria energy enhancing human body immunity function, pachyman has obvious antitumor and protects the liver dirty effect.Poria slightly sweet flavor is put down, and enters the heart, lung, spleen channel.There is eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, effect of mind tranquilizing and the heart calming.Can control dysuria, edema distension, phlegm retention cough with dyspnea, vomiting, malignant histocytosis, has loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful disease such as grade.The diuretic of Poria, is reached by strong activating the spleen pulmonary function, different from the Chinese medicine of other direct diuretic.For diarrhea due to hypofunction of the spleen, leukorrhagia Poria can spleen invigorating, again can eliminating dampness by diuresis, and for having loose bowels caused by insufficiency of the spleen dysfunction of the spleen in transportation and transformation, leukorrhagia, application Poria has the effect of giving consideration to both the incidental and fundamental, the compatibilities such as normal and Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae.Can be used as tonifying the lung spleen, control the adjuvant of the deficiency of vital energy.

The Radix Rehmanniae: the Radix Rehmanniae is also Radix Rehmanniae, the fresh or dry tuber of Scrophulariaceae herbaceos perennial Radix Rehmanniae Rehmannia glutinosa Libosch..Heat clearing away, promote the production of body fluid, moisturize, laxation, removing blood stasis with potent drugs, tissue regeneration promoting, pain relieving, regulating menstruation, the incised wound stasis of blood, removing heat from blood, hemostasis; The effect of Radix Rehmanniae and Radix Rehmanniae is different.Radix Rehmanniae clearing away heat and promoting production of body fluid, can stop blooding and removing heat from blood, is often for consumption of YIN caused by febrile disease, the diseases such as haematemesis, laryngopharynx swelling and pain, crimson tongue excessive thirst, a speckle dermexanthesis and nosebleed heat.Relative to Radix Rehmanniae, Radix Rehmanniae is heat clearing and blood cooling, also can promote the production of body fluid, all right yin nourishing, is used for treatment yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, crimson tongue excessive thirst, sends out the problems such as speckle dermexanthesis.The Radix Rehmanniae is cold in nature, and function is enriching yin and nourishing kidney.Not only promoting the production of body fluid to quench thirst and heat clearing and blood cooling, also have effect to metrorrhagia, menoxenia, frequent fetal movement, constipation etc., every blood system has the people of thermal burn the moon, can often take.If want to treat epidemic febrile disease, qingying decoction can be done with the Radix Rehmanniae; If the later stage for the treatment of epidemic febrile disease, because She's heat does not also disappear to the greatest extent, the Radix Rehmanniae should be used for boiling QINGHAOBIEJIATANG; In addition, contain for heat in blood poison, macule purple is black, and the serious heat of epidemic febrile disease enters the symptom of nutrient blood, can take the Sisheng Wan that the Radix Rehmanniae is made; General want YIN nourishing and the production of body fluid promoting to treat interior-heat quenches one's thirst with constipation, the once liquid soup that the Radix Rehmanniae boils should be eaten.

Fructus Crataegi energy prevention and cure of cardiovascular disease, has blood vessel dilating, heart tonifying, increase coronary flow, improves heart vigor, stimulating central nervous system system, reduces blood pressure and cholesterol, vessel softening and diuresis and sedation; Prevent and treat arteriosclerosis, anti-aging, anticancer effect.Crataegolic acid also has cardiotonic, also benefits to senile heart disease.Its energy appetite-stimulating indigestion-relieving, offsets meat stagnation effect especially better, all have employed Fructus Crataegi in a lot of digestant medicine; Fructus Crataegi has contraction to uterus, anemia of pregnant woman just before giving birth time have the effect expedited the emergence of, and uterine involution in puerperal can be promoted; The immunity of energy enhancing body, has anti-aging, anticancer effect.Having in Fructus Crataegi relievings asthma reduces phlegm, the composition of anti-bacteria, treatment abdominal pain diarrhea.Fructus Crataegi can single or with other foods, compatibility of drugs to improve its dietary function.As Fructus Crataegi slice, GUODANPI, haw jelly etc. have the function such as heart tonifying, blood pressure lowering, blood fat reducing, soft blood vessel, facilitating digestion, be arteriosclerosis, dyspepsia and the ultimate food lacking gastric acid patient.Fructus Crataegi single is made solely holy loose with brown sugar, can activating blood circulation to dissipate blood stasis, promote appetite, help digest, be applicable to congestion in puerperal, stop the after-pains that hinders.

Semen Coicis is conventional Chinese medicine. be again the food generally, often eaten, property slightly sweet flavor is slightly cold, and has inducing diuresis to remove edema, the effect such as spleen invigorating is dried, arthralgia relieving by relaxing muscles and tendons, clearing away heat and discharging pus, is conventional damp-clearing drug.Semen Coicis is again a kind of beauty food, and normal food can keep human body skin gloss fine and smooth, eliminates acne, speckle passeris montani saturati, senile plaque, cyasma, butterfly spot, to desquamation, acne, chap, pachylosis etc. has good efficacy.The kind Renhe root of Semen Coicis can be used as medicine again and cure the disease.Li Shizhen (1518-1593 A.D.) is recorded in Compendium of Material Medica: Semen Coicis energy, and " invigorating spleen and reinforcing stomach, tonifying the lung heat clearing away, removes wind prevailing over dampness.To cook a meal food, control cold air.Decoct drink, diuresis pyretic stranguria." in recent years, a large amount of scientific researches and clinical practice prove, Semen Coicis or a kind of cancer therapy drug, and Preliminary Identification, it can reach more than 35% to the suppression ratio of cancer.

Rhizoma Imperatae cures mainly: cooling blood for hemostasis, heat-clearing and toxic substances removing.For spitting blood, hematuria, pyretic stranguria, edema, jaundice, dysuria, calentura excessive thirst, gastric heat is vomitted the sound of vomiting, coughs." herbal classic ": " main impairment caused by overstrain weakness with emaciation, invigorating the spleen and replenishing QI, except blood stasis, blood close cold and heat, diuresis." " not Lu ": " lower five types of stranguria, except exopathogenic heat is at the intestines and stomach, quenches the thirst, hard muscle, married woman's metrorrhagia.", " book on Chinese herbal medicine justice ": Rhizoma Imperatae, cold and cool and taste is very sweet, the heat that to purify the blood point, and do not hinder drying, not sticky again, therefore removing heat from blood and do not consider its long-pending stasis of blood, tell nosebleed hematemesis to lead.Drop-down fire is inverse, and its effect is very prompt, thus main stomach-fire hiccup vomiting again, lung-heat QI rising in reverse order dyspnea with fullness of the chest.And sweet cold and greasiness liquid, though sending down the abnormal ascending QI and differ from bitter dry, then slake thirst and help produce saliva again, and wash clearly the latent heat between lung gastrointestinal, can rapid digestion of food be treated yearningly dry.Again can treating stranguria closing and control hematuria hematochezia, and housewife female's bleeding due to blood-heat, metrorrhagia drenches band.The little water of tonneau again, the edema of the knot that expels the heat-evil, leads the jaundice of stagnant heat, all sweet cold actual effect of removing heat by catharsis.So its sweet cold power, lets out clearly lung stomach, especially has speciality, all toothache swelling of the gum, all skin ulcers of ulcerative gingivitis dispute, and the strongly fragrant pharyngalgia of stopping up of lung-heat is rotted all cards, and make in order to assistant, effect is the most outstanding, and without abuses.

Radix Paeoniae Rubra, clots absorbing, pain relieving, removing heat from blood, detumescence.Cure mainly: control the stagnant amenorrhea of the stasis of blood, hernia abdominal mass is gathered, suffer from abdominal pain, hypochondriac pain, epistaxis, dysentery, discharging fresh blood stool, conjunctival congestion, carbuncle, injury from falling down.Radix Paeoniae Rubra can purify the blood a point excess-heat, and dissipating blood stasis blood is detained.This product function is close with Cortex Moutan, therefore normal and Cortex Moutan mutual reinforcement between is for use.But the effect of Cortex Moutan clearing away heat and cooling blood is better, can purify the blood a point excess-heat, can control fever due to yin deficiency again; And Radix Paeoniae Rubra can only be used for blood system excess-heat, be good at promoting blood circulation to remove blood stasis." herbal classic ": main pathogen stomachache, except arthralgia due to stagnation of blood, broken hard long-pending, cold and heat hernia abdominal mass, pain relieving, diuresis, QI invigorating.

Pericarpium Citri Reticulatae is warm in nature, acrid in the mouth, bitter in the mouth.Enter spleen channel, stomach warp, lung meridian.Regulating qi-flowing for strengthening spleen, in tune, dampness, reduces phlegm.Cure mainly distension and fullness in the abdomen or pain, the dyspepsia of stagnation of QI in spleen and stomach.Abdominal distention uncomfortable in chest in turbid damp resistance, indigestion and loss of appetite loose stool.Phlegm-damp stops up the cough and asthma of lung.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.Compendium of Material Medica: it is to hundred and always get chess and to regulate the flow of vital energy the merit of dampness, then mending with tonic, then rushes down with cathartic, then rise with Hydrargyri Oxydum Rubrum, then falling with falling medicine.Spleen is the mother of vigour, lung be take the photograph gas want, therefore Pericarpium Citri tangerinae be two through edema caused by disorder of QI want, but with join and reinforcing and reducing lifting also." daily book on Chinese herbal medicine ": can fall apart and can rush down, can temperature can mend, can disappear diaphragm gas, and reduce phlegm saliva, and spleen antitussive, logical five types of stranguria.

Rhizoma Curcumae is pungent, bitter, temperature.Return liver, spleen channel.Cure mainly that " lump in the abdomen, gathers, and dyspepsia does not disappear for coagulation of QI-blood, trusted subordinate's distending pain, and women's blood stasis amenorrhea, traumatic injury is had a pain." there are promoting QI circulation for relieving depression, removing blood stasis with potent drugs, the function of pain relieving.Curcumenol extract and volatile oil raise the mice alanine aminotransferase (ALT) that carbon tetrachloride (CCI4) thioacetamide (TAA) causes obvious reducing effect, sulfobromophthalein sodium (BSP) retention amount is reduced, and corresponding liver tissue lesions alleviates.

The pungent micro-hardship of Rhizoma Cyperi is sweet, and flat function cures mainly: resolving depression of regulating the flow of vital energy, menstruction regulating and pain relieving.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, menoxenia, amenorrhea dysmenorrhea, colic of cold type is suffered from abdominal pain, distending pain of the breast." detailed outline " carries it: loose seasonal epidemic pathogens is trembled with fear epidemic disease, and profit three is burnt, and separate six kinds of stagnation-syndromes, the diet that disappears gathers, phlegm retention feeling of fullness, edema of dorsum of the foot, abdominal distention, beriberi, only trusted subordinate, limbs, head, order, tooth, all pains of ear, ulcer sores, spits blood, hematochezia, hematuria, married woman's bleeding not during menses, the moon wait uncomfortable, before tire puerperal all kinds of diseases and ailments.

Rhizoma Atractylodis are pungent, bitter, temperature.Return spleen, stomach, Liver Channel.Rhizoma Atractylodis have drying damp and strengthening spleen, effect of wind-damp dispelling.Cure mainly retention of dampness in middle-JIAO, anemofrigid-damp arthralgia, foot swelling and pain in knee, flaccidity is soft unable, nyctalopia nyctalopia." pearl sac " day: " stomach invigorating can pacify spleen, non-this of all damp-edema can not remove." Compendium of Material Medica says: " control damp-phlegm prolonged fluid-retention ... and spleen wets dirty, turbid drop leukorrhagia, slidingly rush down hemorrhoidal hamorrhage." " Newly Revised Canon of Materia Medica " claim it can " diuresis ".Rhizoma Atractylodis decoct gastric infusion or alcohol preserved material subcutaneous administration are affected on blood glucose, normal rabbits blood sugar level can be made to raise, but then have hypoglycemic activity to alloxan diabetes rabbit.The Hyperglycemia In Stz-induced Diabetic Rats level that Rhizoma Atractylodis water extract gavage can make chain phleomycin bring out reduces.Have research to think, Rhizoma Atractylodis effective ingredient and adenylic acid play competitive inhibition on same mitochondrion, thus the phosphorylation of T suppression cell internal oxidition, the transfer process of interfering energy.The pharmacological action that effect that Rhizoma Atractylodis are drying damp and strengthening spleen is correlated with is for adjusting gastrointestinal motility function, antiulcer, protecting the liver.Antibacterial etc.The volatile oil that Rhizoma Atractylodis principle active component is is representative with sagittol and hinesol.Rhizoma Atractylodis are on the impact of blood glucose.Anti-hypoxia, CNS inhibition, antitumor, promotion skeleton calcification and on effects such as the impacts of cardiovascular system are then the modern study progress of its pharmacological action.

Herba Taxilli is bitter; Sweet; Property is put down, and enters liver, kidney channel.Invigorating the liver and kidney; Bone and muscle strengthening; Wind-damp dispelling; Antiabortive.Main soreness of waist and knee joint; Muscles and bones flaccidity is weak; Limbs are hemiplegia; Rheumatic arthralgia; Head is wrong dizzy; Frequent fetal movement, metrostaxis.For rheumatic arthralgia, soreness of the waist and knees, muscles and bones is unable, metrorrhagia through many, blood leaking in gestation, frequent fetal movement; Hypertension." herbal classic ": main lumbago, children's's stiffback, carbuncle, antiabortive, fill skin, hard, tooth, long man." not Lu ": main incised wound, goes numbness, woman's metrorrhagia, and internal injury is not enough, puerperal She's disease, lower milk." Japan hanako materia medica ": help muscles and bones, beneficial blood vessels.

Specific embodiment 1:

To gather new new lotus leaf at 6 ~ JIUYUE summer Qiu Erji, removing petiole, is cleaned the slice being cut into 2-4cm, shines to seven, most probably does, put aeration-drying place, mothproof.

Again by all the other raw material Pericarpium Citri Reticulataes, Fructus Crataegi, Rhizoma Polygonati, Semen Coicis, Rhizoma Curcumae, Poria, the Radix Rehmanniae, Rhizoma Cyperi, the Rhizoma Atractylodis Macrocephalae, Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, Rhizoma Imperatae, Rhizoma Atractylodis, Herba Taxilli, extracts to concentrate and makes granule, powder or unguentum.

The extract of the Folium Nelumbinis be mixed with and other raw materials, ultraviolet radiation for sterilizing and disinfecting packs, and directly can take after mixing it with hot water during use.

Specific embodiment 2:

To gather new new lotus leaf at 6 ~ JIUYUE summer Qiu Erji, removing petiole, is cleaned the slice being cut into 2-4cm, shines to seven, most probably does, put aeration-drying place, mothproof, about 5000g.

By surplus stock Pericarpium Citri Reticulatae 1500g, Fructus Crataegi 1500g, Rhizoma Polygonati 1500g, Semen Coicis 1500g, Rhizoma Curcumae 1500g, Poria 1500g, Radix Rehmanniae 1500g, Rhizoma Cyperi 1500g, Rhizoma Atractylodis Macrocephalae 1500g, Radix Salviae Miltiorrhizae 1500g, Radix Paeoniae Rubra 1500g, Rhizoma Imperatae 1500g, Rhizoma Atractylodis 1500g, Herba Taxilli 1500g, clean roguing, dry, be ground into granule, soak 1 hour; Soaked crude drug is put in multi-function extractor and decocts with water secondary; Add up the water of medical material 10 times amount for the first time, decoct 1.5 ~ 2 hours, get decocting liquid, filter; Second time adds up the water of medical material 7 times amount, decocts 1 ~ 1.2 hour, gets twice decocting liquid mixing, filters; The filtrate of filtration inserted in economic benefits and social benefits vacuum concentrator, when being concentrated into 90 DEG C, relative density is the concentrated solution of 1.05, sets to 0 ~ 5 DEG C of deepfreezes 24 hours; Cold preservation liquid is added the filter aid kieselguhr of 0.3%, filter, filtrate is inserted in economic benefits and social benefits vacuum concentrator again, is concentrated into every 1ml containing 1g crude drug amount, adds dextrin and make granule.Again the Folium Nelumbinis prepared is mixed with the granule made, ultraviolet disinfection, pack and get final product.

Specific embodiment 3:

To gather new new lotus leaf at 6 ~ JIUYUE summer Qiu Erji, removing petiole, is cleaned the slice being cut into 2-4cm, shines to seven, most probably does, put aeration-drying place, mothproof, about 3500g; By surplus stock Pericarpium Citri Reticulatae 1100g, Fructus Crataegi 1100g, Rhizoma Polygonati 1100g, Semen Coicis 1200g, Rhizoma Curcumae 1100g, Poria 1100g, Radix Rehmanniae 1100g, Rhizoma Cyperi 1100g, Rhizoma Atractylodis Macrocephalae 1100g, Radix Salviae Miltiorrhizae 1200g, Radix Paeoniae Rubra 1200g, Rhizoma Imperatae 1100g, Rhizoma Atractylodis 1100g, Herba Taxilli 1100g, put into 10 times amount ethanol by surplus stock component, 2 extracting solution each 1 ~ 2 hour, are merged and leave standstill by heating and refluxing extraction 2 times; The medicinal residues of the component raw medicinal material crossed by above-mentioned ethanol extraction again add 10 times of water gaging heating and refluxing extraction 2 times, each 1 ~ 2 hour, are merged by 2 extracting solution and leave standstill; Above-mentioned two kinds of extracting solution are merged; concentrating under reduced pressure relative density is the filtrate of 1.35 (80 DEG C); reclaim ethanol; by gained filtrate adjustment proportion to 1.06; reduce pressure to obtain extractum, then adds Mel and be in harmonious proportion, put into granulator and make 1-2 centimetre of granule; be condensed into pasty state, or convection drying makes powder.The Folium Nelumbinis be mixed with, ultraviolet disinfection, packs and get final product.

Specific embodiment 4:

To gather new new lotus leaf at 6 ~ JIUYUE summer Qiu Erji, removing petiole, is cleaned the slice being cut into 2-4cm, shines to seven, most probably does, put aeration-drying place, mothproof, about 3800g, by surplus stock Pericarpium Citri Reticulatae 1200g, Fructus Crataegi 1400g, Rhizoma Polygonati 1200g, Semen Coicis 1300g, Rhizoma Curcumae 1200g, Poria 1200g, Radix Rehmanniae 1300g, Rhizoma Cyperi 1400g, Rhizoma Atractylodis Macrocephalae 1200g, Radix Salviae Miltiorrhizae 1100g, Radix Paeoniae Rubra 1200g, Rhizoma Imperatae 1200g, Rhizoma Atractylodis 1200g, Herba Taxilli 1300g, add in the ethanol of 5-10 times amount and soak 1-2 hour, heating extraction 2 times, each 1-2 hour, remove supernatant, merge extractive liquid, 100-120 order filters, be the ultrafiltration post ultrafiltration of 5000-10000 again through the molecular weight that dams, when ultrafiltrate concentrating under reduced pressure relative density is 80 DEG C 1.36 extractum, heating is concentrated into paste, stand for standby use, become component 1, again the medicinal residues that ethanol extraction is crossed are put into 10 times of water gagings, heating and refluxing extraction 2 times, each extraction time is 1 ~ 2 hour, and 100-120 order filters, be the ultrafiltration post ultrafiltration of 5000-10000 again through the molecular weight that dams, when ultrafiltrate concentrating under reduced pressure relative density is 80 DEG C 1.36 extractum, heating be concentrated into paste, stand for standby use, become component 2, merge component 1 and component 2 paste making agent, the Folium Nelumbinis that combination system is got ready, pack.

Pharmacological toxicity is tested

One, test material:

(1) laboratory animal: mouse NIH, body weight 25-28g, male and female half and half; Rats Wistar body weight 130-160g, male and female half and half, the feedstuff of rat, mice is provided by Shandong medical college animal experimental center.

(2) test medicine:

1, medicine of the present invention: the oral liquid that embodiment 2 is made, applies with distilled water diluting during three batch equal amount of mixture experiments.

2, positive control medicine: JINGUI SHENQI WAN, commercially available.

Two, test method and result:

(1) get the healthy mice 80 of body weight 25-28g, female, hero half and half, is divided into four groups respectively by sex and body weight, often organizes 20.1, take medicine of the present invention for 2,3 groups, dosage is respectively 8.6g crude drug/kg/d, 6.4g crude drug/kg/d, 4.2g crude drug/kg/d, and take positive control drug JINGUI SHENQI WAN for the 4th group, dosage is 6g crude drug/kg/d, is used in conjunction 15 days.

Result of the test: 1,2,3 groups of mices obviously strengthen than 4 groups of mice sexual excitation degree, the number of copulations of 1,2,3 group of mice average every day increases by 3 times than the number of copulations of 4 groups of mices.

Result of the test shows that medicine of the present invention has obvious excitation to central nervous system, thus medicine of the present invention for adjustment human body function equilibrium, QI invigorating, enrich blood, slow down aging strengthens metabolism, neurolysis, sexual hypofunction has treatment foundation.

Animal acute toxicity test of the present invention

One, test material

(1) animal mouse NIH kind male and female half and half, body weight 20-22g, are provided by Shandong medical college Animal Lab..

(2) test medicine: the health tea that the present invention is made, is diluted with distilled water into suspension.

Two, test method and result:

Mice maximum tolerance determination: get healthy mice 32, male and female half and half, divided three groups within 24 hours, and only, gross weight 1.8ml, is equivalent to crude drug in whole 4.0g to each 0.6ml/ of gavage intestinal, i.e. 100g crude drug/kg/d, is equivalent to 857 times of clinical 65 kilograms of people.After mice administration routinely feedstuff within 12 days, have no animal dead and do not go out, existing toxic reaction.Therefore prove, medicine of the present invention has no side effect, and clinical practice is safe and reliable.

The long-term toxicity test for animals of pharmaceutical composition of the present invention

One, test material and method

(1) test medicine: the health tea decoction agent that the embodiment of the present invention is made.

(2) laboratory animal, healthy rat Wistar, body weight 100-130g, 140 male and female half and half, by sex and body weight random packet, four groups, often organize 35.1, take test medicine for 2,3 groups, dosage is respectively 9.6/kg/d, 6.4/kg/d, 3.2/kg/d.4 groups contrast to the distilled water of respective volume amount, the equal gavage enteral administration of rat, often organize and be once used in conjunction 6 months, put to death half, and under She, all death in 12 days is observed in 1/2 drug withdrawal.

Two, test index

(1) general status comprises body weight, diet, emotion, movable energy.

(2) hemogram checking: red blood cell count(RBC), numeration of leukocyte, platelet count, hemogram etc., quantitative hemoglobin counts.

(3) biochemical analysis, serum albumin quantitatively, cholesterol, blood sugar quantitative.

(4) pathologic diagnosis: get half animal after experimental result and weigh, sacrificed by decapitation, gets blood, solution is treated others for earnest simultaneously, liver, kidney, lung, brain, spleen, gastrointestinal, bladder, adrenal gland do pathologic diagnosis.

Three, result of the test: show through rat chronic toxicity test, with the heavy dose of coloclysis of the present invention six months, increases the growth of rat, body weight, all has no side effect to brain, Liver and kidney function.Do not find that infringement changes to each histoorgan of rat, blood circulation, medication group compares no significant difference with matched group.Illustrate that medicine of the present invention has warming and recuperating the kidney-YANG, QI invigorating, enriches blood, slow down aging strengthens the drug effects such as metabolism, avirulence.

Pharmacological experiment:

The patient of the serious diseases such as the coronary heart disease caused by obesity, hyperlipidemia constantly increases, and has researched and proposed new requirement thus to associated treatment medicine, and the drug research in blood fat reducing, fat-reducing and exploitation significantly increase.Herein by setting up rat nutritive obesity, investigate the impact of extract for nutritive obesity in rats and blood lipids index, to the pharmacological of clear and definite the present invention in Weight-reducing and lipid-lowering.

1.1 materials and instrument

1.1.1 animal

SD rat, cleaning grade, body weight (225 ± 25) g, animal is provided by Shandong University's medical college Experimental Animal Center.

1.1.2 instrument

LD type electronic balance (Shenyang Longteng Electronic Co., Ltd.); OLYMPUS AU100 type fully automatic blood biochemistry analyzer (Japanese Olympus company).

1.1.3 medicine and reagent

Cholesterol: Tianjin Bo Di Chemical Co., Ltd., lot number: 20050127, sodium cholate: Haidian District, Beijing City microbiological culture media products factory, lot number: 20030826, sucrose: Guangxi Boqing Food Co., Ltd. bosom person sugar refinery, lot number: 051106.Adeps Sus domestica: self-control.0.9% sodium chloride injection (Binghu Shuanghe Pharmaceutical Co., Ltd., Wuhan, lot number 20060604). all the other reagent are domestic commercially available analytical pure.

Serum total cholesterol (TCH) test kit, lot number 2006090002

Triglyceride (TG) measures test kit, lot number 2006080574

HDL-C (HDL.C) measures test kit, lot number 2006080317

The same alcohol of low density lipoprotein, LDL gallbladder (LDL.C) measures test kit, lot number 2006080265

Above testing cassete provides by Zhejiang Dong Ou biological engineering company limited.

1.2.2 the mensuration of weight-reducing experiment and blood fat

The rat of fat group, by body weight random packet, often organizes 10.Normal group normal diet is fed, model group and administration group all with high fat diet feed, gastric infusion, matched group and model group gavage give isometric normal saline, each group gavage 30 days all continuously.Weigh in weekly, body is long, calculate Lee ' S index [body weight (g) cubic root x10 ³/ body long (nose to anus, era)], eye socket gets blood, measures Serum TC, TG, HDL-C, LDL-C value respectively, is all taken off by the fat of rat abdominal cavity surrounding genital after blood drawing, claim its weight in wet base.

The mensuration of blood fat:

TC measures: adopt CHOD.PAP method, test philosophy is for first to use cholesterol ester hydrolase (CEH) same for gallbladder in serum alcohol ester (CE) to be hydrolyzed to free cholesterol (FC) and fatty acid; Use cholesterol oxidase (COD) by owning in serum again, FC is oxidized to Ch-4. alkene 1 ketone, and produces H202; The latter and 4. amino-antipyrines (4-AAP) and phenol react (Trinder reacts) and generate red quinone imines, in the colorimetric determination of 470 ~ 550nm wavelength under peroxidase (POD) acts on.

TG measures: adopt GPO.PAP enzyme process to improve and form, in order to get rid of the interference of original dissociative glycerin (FC) in serum, reagent is divided into two parts, lipoproteinesterase (LPL) and 4-AAP are reagent II, and other parts are reagent I.First reagent adding I in serum, make FC under the effect of GPO (GPO) and glycerol kinase (GK), generate H202, finally under the effect of POD, present Trinder with 4 monochlorphenols (4-CP) and 4.AAP to react, generate red quinone imines, in the colorimetric determination of 480--, 520nm wave-length coverage.

The mensuration of LDL-C: adopt polyvinyl sulfuric acid salt (PVS) sedimentation method, test philosophy is that the HDL in serum can be precipitated by PVS, VLDL and LDL is still present in supernatant, with aforesaid enzymatic assays serum TC with on the basis of this supernatant C h, subtract the latter from the former, be LDL-C.

The mensuration of HDL-C: adopt phosphotungstic acid. magnesium precipitate method.HDL is not containing the lipoprotein of apolipoprotein B (apoB), can utilize phosphotungstic acid. azoviolet by lipoprotein (LDL, VLDL and CM) the precipitation removing containing apoB in serum, and then measures the Ch in supernatant, is above HDL-C.The results are shown in Table 1,2,3,4.

Table 1 the present invention is on the impact (X ± S, n=10) of rat body weight

Group	Dosage (g/kg)	Lee ' index fat is heavy
			Matched group	-	1.644±0.313
Model group	-	1.965±0.179
			Low dosage of the present invention	1.5	1.773±0.122Δ
Dosage in the present invention	3	1.685±0.193ΔΔ
			High dose of the present invention	4.5	1.732±0.156ΔΔ

Note: compare with matched group: Δ P < 0.01; Compare with model group: Δ Δ P < 0.01.

2.2 lotus leaf health-care teas are on the impact of rat fat

The blood lipid level (TG, TC, HDL-C) of each animal is measured, according to TC and reference weight random packet before experiment; The blood lipid level of each treated animal is again measured at the end of experiment.Statistical result is in table 2, table 3, table 4.

Table 2 the present invention keeps healthy the impact (X ± SD) of the bitter edible plant on serum TC before and after rat experiment

Table 3 health tea of the present invention is on the impact (X ± SD) of serum TG before and after rat experiment

Table 4 health tea of the present invention is on the impact (X ± SD) of Serum HDL-C before and after rat experiment

Note: table 2,3, same letter represents there was no significant difference a=0.05 in 4 footmarks, different alphabet is shown with significant difference b=0.05.

Result shows, each dosage group of the present invention all obviously can suppress the increase of rat body weight, and Lee ' s index, fat heavily decline, and compares have significant difference (P < 0.05 or P < 0.01) with model group.The present invention makes serum TC level obviously reduce, and high, middle dosage group compares with model group to be had significantly and pole significant difference (P < 0.05 and P < 0.01).It also can reduce TG, raise HDL-C/LDL-C, but only high dose group has significant effect (P < 0.05).Show the present invention, to alimentary obesity, there is certain antiobesity action, the symptom that fat caused blood fat raises can be alleviated simultaneously.

3, brief summary

Of the present invention extract of this experimentation based on Folium Nelumbinis is on the impact of nutritive obesity in rats body weight and blood fat.Result shows, and this composition can significantly suppress rat body weight to increase; Meanwhile, each blood lipids index all improves significantly, and Serum TC and TG decline all to some extent, and TC declines more obvious, shows that this medicine may mainly act on serum TC; Experimental session, without obviously diarrhoea and the generation of appetite-suppressing phenomenon, on rat body constitution endurance also without significantly impact, shows that this extract has good fat-reducing effect.

Record according to " (Compendium of Materia Medica ": " Folium Nelumbinis takes it, makes us thin bad ", Folium Nelumbinis has blood vessel dilating, blood pressure lowering and blood fat reducing, the clear effect such as swollen.Folium Nelumbinis is mainly containing nuciferine, liensinine and Flavonoid substances etc., and it has good functions of lowering blood-fat and reducing weight.Record according to Chinese Pharmacopoeia: Fructus Crataegi energy promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis, for meat stagnation, gastral cavilty distension, dysentery stomachache, hyperlipidemia; The clearing away heat to improve acuity of vision of Rhizoma Curcumae energy, loosening bowel to relieve constipation, puckeryly to lead to for conjunctival congestion, dizzy, constipation of having a headache.Fructus Crataegi and Fructus Crataegi flavone are mainly through regulating rat liver low density lipoprotein receptor (LDLR) transcriptional level and improving oxidation resistance, and anti-lipid peroxidation thing prevents lipid metabolic disorder.Rhizoma Atractylodis, it has good oxidation resistance and eliminates the ability of free radical, has blood fat reducing and blood glucose, blood pressure lowering and the function such as cholesterol and mutation.Lotus leaf health-care tea take theory of Chinese medical science as foundation, and selected Folium Nelumbinis, Fructus Crataegi, Rhizoma Curcumae, Rhizoma Atractylodis, Radix Salviae Miltiorrhizae are raw material, refines form through scientific composition, and object is in order to product has fat-reducing and adjusting blood lipid function simultaneously.

This experiment carries out animal experiment in strict accordance with " function of health food assessment process and the method for inspection ", result shows that health tea of the present invention has adjusting blood lipid, the effect of fat-reducing, for utilizing Chinese herbal medicine to prepare adjusting blood lipid, the health food of fat-reducing provides certain theory and experimental basis.

Claims

1. for a Folium Nelumbinis diet tea for obese people, it is characterized in that, the parts by weight of the various raw materials of described diet tea comprise: 10 ~ 50 parts, Folium Nelumbinis, Pericarpium Citri Reticulatae 10 ~ 20 parts, Fructus Crataegi 10 ~ 20 parts, Rhizoma Polygonati 10 ~ 20 parts, Semen Coicis 10 ~ 20 parts, Rhizoma Curcumae 10 ~ 20 parts, 10 ~ 20 parts, Poria, 10 ~ 20 parts, the Radix Rehmanniae, Rhizoma Cyperi 10 ~ 20 parts, the Rhizoma Atractylodis Macrocephalae 10 ~ 20 parts, Radix Salviae Miltiorrhizae 10 ~ 20 parts, Radix Paeoniae Rubra 10 ~ 20 parts, Rhizoma Imperatae 10 ~ 20 parts, Rhizoma Atractylodis 10 ~ 20 parts, Herba Taxilli 10 ~ 20 parts.

2. a kind of Folium Nelumbinis diet tea for obese people according to claim 1, it is characterized in that, the parts by weight of the various raw materials of described diet tea comprise: 10 ~ 40 parts, Folium Nelumbinis, Pericarpium Citri Reticulatae 10 ~ 15 parts, Fructus Crataegi 10 ~ 15 parts, Rhizoma Polygonati 10 ~ 15 parts, Semen Coicis 10 ~ 15 parts, Rhizoma Curcumae 10 ~ 15 parts, 10 ~ 15 parts, Poria, 10 ~ 15 parts, the Radix Rehmanniae, Rhizoma Cyperi 10 ~ 20 parts, the Rhizoma Atractylodis Macrocephalae 10 ~ 20 parts, Radix Salviae Miltiorrhizae 10 ~ 20 parts, Radix Paeoniae Rubra 10 ~ 20 parts, Rhizoma Imperatae 10 ~ 20 parts, Rhizoma Atractylodis 10 ~ 20 parts, Herba Taxilli 10 ~ 20 parts.

3. a kind of Folium Nelumbinis diet tea for obese people according to claim 1, it is characterized in that, the parts by weight of the various raw materials of described diet tea comprise: 10 ~ 30 parts, Folium Nelumbinis, Pericarpium Citri Reticulatae 10 ~ 20 parts, Fructus Crataegi 10 ~ 20 parts, Rhizoma Polygonati 10 ~ 20 parts, Semen Coicis 10 ~ 20 parts, Rhizoma Curcumae 10 ~ 20 parts, 10 ~ 20 parts, Poria, 10 ~ 20 parts, the Radix Rehmanniae, Rhizoma Cyperi 10 ~ 15 parts, the Rhizoma Atractylodis Macrocephalae 10 ~ 15 parts, Radix Salviae Miltiorrhizae 10 ~ 15 parts, Radix Paeoniae Rubra 10 ~ 15 parts, Rhizoma Imperatae 10 ~ 15 parts, Rhizoma Atractylodis 10 ~ 15 parts, Herba Taxilli 10 ~ 15 parts.

4. as described in any one of claims 1 to 3 item for a preparation method for the Folium Nelumbinis diet tea of obese people, it is characterized in that, the preparation process of described diet tea comprises:

A. the preparation of Folium Nelumbinis;

5., according to claim 4 for the preparation method of the Folium Nelumbinis diet tea of obese people, it is characterized in that, in described step a, gather at 6 ~ JIUYUE summer Qiu Erji, removing petiole, is cleaned the slice being cut into 2-4cm, solarization is done to seven, eighty per cant, puts aeration-drying place, mothproof.

6. the preparation method of the lotus leaf health-care tea of hypoglycemic according to claim 4, is characterized in that, in described step b, by all the other crude drug roguings, dry, be ground into granule, soak 1 hour; Soaked raw material is put in multi-function extractor and decocts with water secondary; Add up the water of medical material 10 times amount for the first time, decoct 1.5 ~ 2 hours, get decocting liquid, filter; Second time adds the water of total amount 7 times amount, decocts 1 ~ 1.2 hour, gets twice decocting liquid mixing, filters; Heating is concentrated into pasty state filtrate, stand for standby use.

7. according to claim 4 for the preparation method of the Folium Nelumbinis diet tea of obese people, it is characterized in that, in described step c, the filtrate of filtration is inserted in economic benefits and social benefits vacuum concentrator, when being concentrated into 90 DEG C, relative density is the concentrated solution of 1.05, sets to 0 ~ 5 DEG C of deepfreezes 24 hours; Cold preservation liquid is added the filter aid kieselguhr of 0.3%, filter, filtrate is inserted in economic benefits and social benefits vacuum concentrator again, is concentrated into every 1ml containing 1g crude drug amount, convection drying powdered, or adds dextrin and make granule.

8. according to claim 4 for the preparation method of the Folium Nelumbinis diet tea of obese people, it is characterized in that, in described steps d, the powder prepare the Folium Nelumbinis prepared and surplus stock or granule mix, and ultraviolet disinfection is packed and be get final product.

9. basis is for a preparation method for the Folium Nelumbinis diet tea of obese people as described in any one of claims 1 to 3 item, it is characterized in that, when granule made by other raw materials of described health tea, step can also be:

C, by 2-in-1 and concentrated to component 1 and component; Lixiviate.

10. according to claim 9 for the preparation method of the Folium Nelumbinis diet tea of obese people, it is characterized in that: in described step a, get raw material and add in the ethanol of 5-10 times amount and soak 1-2 hour, then put into extraction pot heated and boiled 1 hour, filter, filtrate is for subsequent use; For component 1; In described step b, filtering residue adds water, and second time heating, boils 45 minutes, and filter, filtrate is for subsequent use; Filtering residue adds water again, heated and boiled half an hour third time, filters; For component 2; In described step c, three filtrates be combined, by filtered through gauze, add 50-60% ethanol in residue, 60 DEG C-70 DEG C are continued lixiviate 2h, and every 10min stirs once, filtered through gauze, merge lixiviating solution, are condensed into pasty state and add Mel and put into granulator and granulate dry.