CN108185541A - A kind of graphene socks for improving patient with diabetic feet microcirculation and preparation method thereof - Google Patents
A kind of graphene socks for improving patient with diabetic feet microcirculation and preparation method thereof Download PDFInfo
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- CN108185541A CN108185541A CN201810211453.7A CN201810211453A CN108185541A CN 108185541 A CN108185541 A CN 108185541A CN 201810211453 A CN201810211453 A CN 201810211453A CN 108185541 A CN108185541 A CN 108185541A
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- A—HUMAN NECESSITIES
- A41—WEARING APPAREL
- A41B—SHIRTS; UNDERWEAR; BABY LINEN; HANDKERCHIEFS
- A41B11/00—Hosiery; Panti-hose
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- A—HUMAN NECESSITIES
- A41—WEARING APPAREL
- A41B—SHIRTS; UNDERWEAR; BABY LINEN; HANDKERCHIEFS
- A41B17/00—Selection of special materials for underwear
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/24—Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K36/634—Forsythia
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
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- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
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Abstract
The present invention provides a kind of graphene socks for improving patient with diabetic feet microcirculation and preparation method thereof, belong to technical field of graphene, including sock body, sock body is double-layer structure, for stocking sole outer layer close to heel part setting, there are one slide fastener, stocking sole internal layer is coated with graphene polyethylene glycol dimethacrylate nanometer layer, stocking sole outer layer and stocking sole internal layer centre form a cavity, built-in dismountable Chinese medicine package, Chinese medicine composition are prepared by following Chinese medicine material：Honeysuckle, dandelion, Chinese cassia tree, purslane, moutan bark, rhizoma atractylodis, Chinese violet, uncaria, Radix Angelicae Sinensis, Rhizoma Chuanxiong, wild chrysanthemum, the coptis, Cortex Eucommiae, Fructus Forsythiae, caulis trachelospermi, the root bark of Chinese wolf-berry.For the socks of the present invention in terms of patient with diabetic feet microcirculation is improved, clinical effectiveness is notable, can easily be adhered to, be easily accepted by patients, had no adverse reaction with other diseases such as auxiliary treatment liver kidneys.Graphene socks easily wash, can Reusability, economize on resources.
Description
Technical field
The invention belongs to technical field of graphene, and in particular to a kind of graphene socks for improving patient with diabetic feet microcirculation
Son and preparation method thereof.
Background technology
Graphene is a kind of quasi- two-dimensional material there are one atomic layer level thickness, does monoatomic layer graphite so being called, is
A kind of material with healthy functions has strong heat preservation, moisture absorption, antibacterial, conciliation endocrine, promotes microcirculation, the improvement mankind sub-
The unique effect of health status.
Diabetes (DF) are one of chronic complicating diseases of diabetes, with Lower Distal Extremities dysautonomia and different degrees of Peripheral blood
The relevant foot ulcers of pipe lesion, infection and (or) deep tissues destroy, and the lighter shows as foot deformity, dry skin and hair
Cool, callosity, severe one may occur in which foot ulcers, gangrene, be the main reason for causing diabetic's limbs maimed, to drastically influence
The quality of life of patient.The middle-aged and the old is the group of people at high risk of diabetes, this kind of crowd is often with decreased liver function, kidney function
The illnesss such as energy reduction.
The chemical drugs side effect of prior art treatment diabetes is big, and adverse reaction is more；Chinese medicine treatment passes through decoction more
Mode takes orally, bitter, and decoction method trouble, patient is not easy to adhere to taking medicine, and clinical effectiveness is bad.Prior art discloses a kind of tools
There are the graphene socks for the effect of promoting blood circulation, medicinal powder discharged by the circular hole of arc convex on the stocking sole, is promoted blood circulation,
But there are problems that medicinal powder is constantly discharged, graphene socks cannot be reused.In addition, graphene disclosed in the prior art
Hosiery material is simply mixed for graphene with cotton material, and the effect to promote blood circulation is poor, it is impossible to reach thorough improvement
The effect of patient with diabetic feet microcirculation.
Invention content
The present invention provides a kind of graphene socks for improving patient with diabetic feet microcirculation and preparation method thereof, solve existing
There are graphene socks in technology that cannot reuse, oral traditional Chinese medicine treatment diabetes decoct trouble, are not easy to adhere to, clinical effectiveness
The problem of bad.
To achieve these goals, the present invention adopts the following technical scheme that：
A kind of graphene socks for improving patient with diabetic feet microcirculation, including sock body, at the top of the sock body
It is provided with stretch cord, the sock body bottom is double-deck, from outside to inside respectively stocking sole outer layer, stocking sole internal layer, outside the stocking sole
Layer is close to heel part setting, there are one slide fasteners, and the zipper length and stocking sole outer layer are of same size, and the stocking sole internal layer applies
There is graphene-polyethylene glycol dimethacrylate nanometer layer, a cavity formed among the stocking sole outer layer and stocking sole internal layer,
Removably improve the Chinese medicine package of patient with diabetic feet microcirculation built in the cavity, the Chinese medicine package is by waterproof isolation film and close
Envelope be filled in the isolation film Chinese medicine composition composition, the Chinese medicine composition be powder, the Chinese medicine composition by with
The Chinese medicine of lower parts by weight is prepared：
20~30 parts of honeysuckle, 20~30 parts of dandelion, 15~25 parts of Chinese cassia tree, 12~20 parts of purslane, moutan bark 10~
15 parts, 10~15 parts of rhizoma atractylodis, 8~15 parts of Chinese violet, 8~15 parts of uncaria, 8~15 parts of Radix Angelicae Sinensis, 10~15 parts of Rhizoma Chuanxiong, wild chrysanthemum
6~10 parts, 6~10 parts of the coptis, 6~10 parts of Cortex Eucommiae, 2~4 parts of Fructus Forsythiae, 6~12 parts of caulis trachelospermi, 2~4 parts of the root bark of Chinese wolf-berry.
Preferably, the sock body is formed by cotton fiber and graphene fiber mixed textile.
Preferably, the Chinese medicine composition is prepared by the Chinese medicine of following parts by weight：25 parts of honeysuckle, dandelion 28
Part, 20 parts of Chinese cassia tree,
16 parts of purslane, 12 parts of moutan bark, 12 parts of rhizoma atractylodis, 10 parts of Chinese violet, 12 parts of uncaria, 10 parts of Radix Angelicae Sinensis, Rhizoma Chuanxiong 12
Part, 8 parts of wild chrysanthemum, 8 parts of the coptis, 8 parts of Cortex Eucommiae, 4 parts of Fructus Forsythiae, 4 parts of caulis trachelospermi, 4 parts of the root bark of Chinese wolf-berry.
Preferably, the Chinese medicine composition is evenly laid out in Chinese medicine package.
Preferably, the Chinese medicine composition thickness is 1~2cm.
Preferably, the Chinese medicine composition thickness is 1.5cm.
Preferably, the waterproof isolation film is PE isolation films.
Preferably, the stocking sole superficies are zigzag anti-skid structure.
Preferably, it is provided with tightness-adjustable button on the stretch cord.
Preferably, the stretch cord circular array setting.
The invention also includes a kind of preparation method for the graphene socks for improving patient with diabetic feet microcirculation, including following
Step：
(1) preparation of sock body
Traditional cotton fiber may be used in sock body material, and cotton fiber and graphene fiber mixing can also be used to spin
It knits.
The wherein compound sock body preparation method of cotton fiber-graphene fiber is as follows：
Graphene oxide is prepared using Hummers methods first, which is placed in dispersion in ultrasonic wave realizes stripping, obtains
To graphene oxide acid dispersion；Dispersion liquid with 3,4-rthylene dioxythiophene is mixed, is stirred evenly, centrifuge is sent into and carries out
Centrifugal treating obtains sediment；Sediment is dried, by dried sediment：Cotton fiber is according to 1~3：90~100
Weight ratio mixing, squeezed out by screw extruder melt blending, then be granulated, then after spinning, winding, stretching be made.
(2) preparation of graphene-polyethylene glycol dimethacrylate nanometer layer
Graphene oxide nanometer sheet is prepared using modified Hummers methods first；Then, certain mass is accurately measured
Ethylene glycol dimethacrylate, Macrogol 6000, dimethylformamide azodiisobutyronitrile, ultrasound are vortexed to being clarified
Solution.Graphene is added in into above-mentioned solution, makes its a concentration of 1.0mg/mL, then ultrasound 30min is obtained in recirculated water
The conventional cloth that can make the stocking sole is impregnated in the solution, is reacted in micro-wave oven, microwave reaction by finely dispersed solution
After with Medical forceps carefully will be bonded with nano coating cloth take out, with volume ratio be 1:1 methanol/water solution cleaning
Coating, 40 DEG C of low temperature dryings are spare.
(3) preparation of traditional Chinese powder medicine
By 20~30 parts of honeysuckle, 20~30 parts of dandelion, 8~15 parts of Chinese violet, 6~10 parts of wild chrysanthemum, the coptis 6~
10 parts are put into 2~4 parts of Fructus Forsythiae in marmite, and clear water is added in into marmite, medicinal material 2-4cm is flooded, is first boiled by fire, is being used
It is boiled with soft fire 55-58 minutes, filters the dregs of a decoction using gauze, obtain liquid, it is spare；By 15~25 parts of Chinese cassia tree, 12~20 parts of purslane,
10~15 parts of moutan bark, 10~15 parts of rhizoma atractylodis, 8~15 parts of uncaria, 8~15 parts of Radix Angelicae Sinensis, 10~15 parts of Rhizoma Chuanxiong, 6~10 parts of Cortex Eucommiae,
In 2~4 parts of 6~12 parts of caulis trachelospermi, root bark of Chinese wolf-berry input drying boxes, it is 75-85 DEG C to keep temperature, 25-30 minutes dry, obtains original
Material；Gained raw material is put into steel mill, holding rotating speed is 4000-4500r/min, and crushing obtains 60 mesh medicinal powder；By gained medicine
Powder is put into the liquid prepared and is uniformly mixed, and reinjects in evaporating dish, is heated using moderate heat, treats that moisture fully steams
Traditional Chinese powder medicine is obtained after distributing.
(4) traditional Chinese powder medicine that obtains step (3) is evenly laid out on waterproof isolation film, vacuumizes, seals, make Chinese medicine
Powder cannot move freely in Chinese medicine package.
(5) prepared by the sock body and step (2) prepared step (1) is coated with graphene-polyethylene glycol dimethyl propylene
The stocking sole internal layer suture of olefin(e) acid ester nanometer layer, sock body top are provided with stretch cord, stocking sole outer layer and stocking sole internal layer centre shape
1 slide fastener is set close to heel part into a cavity, and in stocking sole outer layer, zipper length and stocking sole outer layer are of same size, empty
Chamber length and width are respectively greater than the length and width of Chinese medicine package, with the dismounting of convenient Chinese packet.
Raw material effect and main disease to be treated of traditional Chinese powder medicine described above are as follows：
Honeysuckle：It is cold in nature, it is sweet in flavor, enter lung, the heart, stomach, have effects that clearing heat and detoxicating, anti-inflammatory, qi-restoratives treats wind, cure mainly swollen
Completely descend disease, warm disease heating, the diseases such as heat toxin large carbuncle and tumour.
Dandelion：Cold in nature, bitter but sweet flavor enters liver, stomach, clearing heat and detoxicating, diuresis dissipating bind.Control acute mastitis, adenolymphitis,
Scrofula, boil poisonous soreness, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis,
Urinary tract infections.
Chinese cassia tree：Complement sun, warming spleen and stomach, removing internal cold, promoting blood circulation.The Yang-function insufficiency of kidneyzang, cold weak pulse of limb are controlled, yang depletion is collapsed, and abdominal pain is let out
It rushes down, cold hernia run quickly globefish, waist and knee crymodynia, Amenorrhea abdominal mass, cloudy subcutaneous ulcer, streamer and empty sun are floating more, heat in the upper and cold in the lower.
Purslane：It is warm-natured, acrid flavour.Edible purslane leaf can treat malaria, postpartum abnormal sweating, postpartum bloody flux, urinary obstruction,
Periumbilical pain, children's bloody flux, urine heat gonorrhea, centipde-bite.
Moutan bark：It is cold in nature, bitter；It is cool；It is slightly cold.The thoughts of returning home；Liver；Kidney；Lung channel.With clearing heat and cooling blood, the effect of promoting blood circulation to remove blood stasis.
It cures mainly：Warm heat disease heat invading xuefen；Send out spot；Hematemesis；Pyreticosis later stage hot Fu Yin distributions heat；Deficiency of Yin osteopyrexia and fever；Amenorrhea due to stagnation of blood；Bitterly
Through；Carbuncle sore tumefacting virus；The pain of injury caused by falling and tumbling；Beriberoid pyretic arthralgia.
Rhizoma atractylodis：Acrid flavour；It is bitter；It is warm-natured.Returns spleen；Stomach；Liver Channel.With drying damp and strengthening spleen, the effect of wind-damp dispelling, improving eyesight.It cures mainly：It is tired
It is idle thermophilic sleeping；Born of the same parents' ruffian abdominal distension；Loss of appetite；Vomiting and having loose bowel；Phlegm and retained fluid；It is wet swollen；Exterior syndrome folder is wet；Head body weight pain；Bi Zheng warm nature；Podomere acid
Pain weighs；Impotence folds in a garment；Yctalopia.
Chinese violet：Taste bitter, acrid, cold.Distributed in heart and lung channels.With clearing heat and detoxicating, cool blood detumescence, the effect of clearing heat and promoting diuresis is main
Control furunculosis, carbuncle swells, scrofula, jaundice, dysentery, diarrhea, hot eyes, larynx numbness, venomous snake bite.
Uncaria：Sweet-bitter flavor；Cold nature.Return liver warp, the heart channel of Hang-Shaoyin.Function：The flat liver of heat-clearing；Relieving convulsion and spasm.It cures mainly：Child convulsion；
The morbid night crying of babies；Excess heat moves wind；Eclampsia；Dizziness due to hyperactivity of liver-YANG；Irascibility distending pain in the head.
Radix Angelicae Sinensis：Taste sweet, warm.Return liver, the heart, the spleen channel.With enriching blood；Promoting blood circulation；Menstruction regulating and pain relieving；The effect of moisturize laxation.Main blood
Empty all cards；Irregular menstruation；Amenorrhea；Dysmenorrhoea；Abdominal mass knot gathers；Uterine bleeding；Asthenia cold abdominalgia；Impotence numbness；Numbness；Intestines are dry and shit is difficult；Dysentery characterized by blood in the stool
After weigh；Ulcer sores；Injury from falling down.
Rhizoma Chuanxiong：Acrid flavour, it is warm-natured.Return liver, courage, pericardium channel.Blood-activating and qi-promoting, wind-expelling pain-stopping.For pacifying nerve, positive intermittent headache head
Bitterly, abdominal mass abdominal pain, chest side of body shouting pain, tumbling and swelling, headache, arthralgia pain due to rheumatism.
Wild chrysanthemum：Cold nature, tool dispelling wind and heat from the body, subdhing swelling and detoxicating.Furunculosis carbuncle swells, abscess of throat, wind-fire red eye, head can be treated
The diseases such as pain dizziness.
The coptis：Bitter, it is cold in nature.The thoughts of returning home, spleen, stomach, liver, courage, large intestine channel.Heat-clearing and damp-drying drug, purging intense heat and detonicating.For damp and hot ruffian
Full, vomiting gulps down
Acid, rush down dysentery, jaundice, unconsciousness due to high fever, heart-fire hyperactivity, dysphoria and insomnia, blood-head tells nosebleed, hot eyes, toothache are quenched one's thirst, carbuncle swells
Furunculosis；Eczema, wet sore are controlled outside, duct is suppurated.
Cortex Eucommiae：It is sweet in flavor, it is warm-natured.Tonify the liver and kidney, strengthen muscles and bones, coordinating Chong and Conception Vessels, strengthen meridian and miscarriage prevention the effect of.Kidney yang can be treated
Pain in waist and lower extremities caused by void is aching and limp powerless, and born of the same parents' tire caused by liver- qi invasion is not solid, and wet itch of scrotum waits diseases.
Fructus Forsythiae：Bitter cool in nature, clearing heat and detoxicating, dispersing swelling and dissipating binds.For ulcer, scrofula, acute mastitis, erysipelas, anemopyretic cold, warm disease
From the beginning of warm is joined the army, hyperpyrexia polydipsia, coma hair spot, heat gonorrhea renal shutdown.
Caulis trachelospermi：Cold nature, bitter.Dispelling wind and removing obstruction in the meridians, cool blood detumescence.For beriberoid pyretic arthralgia, muscle arteries and veins contraction, soreness of waist and knee joint,
Larynx numbness, carbuncle swells, injury from falling down.
The root bark of Chinese wolf-berry：It is cold in nature, it is sweet in flavor.Alias Chinese wolfberry skin is Solanaceae, Lycium, is the root skin of matrimony vine.It can be used as medicine, have
There is the benefits of bringing down a fever except steaming, cool blood is except steaming, clearing lung-heat fall fire and other effects.
Advantageous effect：
What the present invention protected is a kind of graphene socks for improving patient with diabetic feet microcirculation, compared with prior art,
The stocking sole uses double-layer structure, and outer layer can be used that graphene-cotton fiber is blended to be formed, and graphene can be emitting far-infrared, can
It is effectively improved the microcirculation of patient with diabetic feet foot；Stocking sole outer layer can also be made of common cotton fiber, be greatlyd save
Production cost.Stocking sole internal layer is made of the cloth for being coated with graphene-polyethylene glycol dimethacrylate nanometer layer, graphite
Alkene-polyethylene glycol dimethacrylate nanometer layer is in direct contact the foot of patient with diabetic feet, plays and promotes blood circulation, inhales
The double action of attached foot moisture.
A cavity is formed among stocking sole outer layer and stocking sole internal layer, built-in Chinese medicine package is detachable, facilitates graphene socks
Cleaning, solve the problems, such as that graphene socks of the prior art containing Chinese medicine composition are unable to Reusability；Meanwhile the prior art
It is middle impregnated socks made of the grapheme material of Chinese medicine cleaning when, effective component of chinese medicine can with washing times increase by
It is decrescence few, and during the graphene socks cleaning of the present invention, it unzips, Chinese medicine package is taken out, in thus completely saving
The ingredient of powdered medicine, blood circulation effect are more longlasting.Chinese medicine material in Chinese medicine package have it is clearing heat and detoxicating, promote blood circulation,
The multi-efficiencies such as calming the liver to stop the wind, tonifying kidney and strengthening yang, while improving patient with diabetic feet foot microcirculation, to decreased liver function, kidney
The patient that function reduces plays certain therapeutic effect, reduces medication type, improves the quality of life of glycosuria disease foot patient；
Chinese medicine package is placed in socks, does not need to oral drugs, is effectively prevented patient and is taken side effect and the oral traditional Chinese medicine that Western medicine is brought
The shortcomings that decocting trouble, being not easy to adhere to.
The zigzag anti-skid structure of stocking sole superficies increases the frictional force of socks and shoes, plays anti-skidding effect.
There is tightness-adjustable button on stretch cord, patient with diabetic feet is facilitated to adjust the elasticity of socks according to the size of the foot of oneself.In addition,
Stretch cord circular array is set, and socks can be made to be not easy to fall.
To sum up, the present invention is the technical solution by being obtained after graphene socks of the prior art are improved, and is being improved
In terms of patient with diabetic feet microcirculation, clinical effectiveness is notable, can easily be adhered to, easily with other diseases such as auxiliary treatment liver kidneys
It is accepted by patients, has no adverse reaction.Graphene socks easily wash, can Reusability, economize on resources.
Description of the drawings
Fig. 1 is the overall structure figure of the embodiment of the present invention 1；
Fig. 2 is the overall structure figure of the embodiment of the present invention 2；
Fig. 3 is the front schematic view of the stocking sole of the present invention.
Attached drawing identifies：1- sock bodies；2- stocking sole internal layers；3- stocking sole outer layers；4- cavitys；5- stretch cords；6- slide fasteners；7- feet
With；8- annular arrays；9- zigzag anti-skid structures；10- tightness-adjustable buttons；The 11- stockings sole.
Specific embodiment
In order to which the purpose of the present invention, technical solution and advantageous effect is more clearly understood, below in conjunction with specific embodiment,
The present invention will be described in further detail.It should be appreciated that specific embodiment described herein is only to explain the present invention, and
It is not construed as limiting the invention.
Embodiment 1
Refering to Fig. 1 and Fig. 3, a kind of graphene socks for improving patient with diabetic feet microcirculation, including sock body 1, socks
The material for preparing of sub- ontology 1 is formed for cotton fiber and graphene fiber mixed textile.1 top of sock body is provided with stretch cord 5,
Battle array 8 is set stretch cord 5 in a ring, and 1 bottom of sock body is double-layer structure, from outside to inside respectively stocking sole outer layer 3, stocking sole internal layer
2.3 surface of stocking sole outer layer is zigzag anti-skid structure 9.There are one slide fastener 6, slide fasteners in close 7 part of heel setting for stocking sole outer layer 3
6 length and stocking sole outer layer 3 are of same size, and stocking sole internal layer 2 is coated with graphene-polyethylene glycol dimethacrylate nanometer layer (Fig. 1
In do not identify).A cavity 4 is formed among stocking sole outer layer 3 and stocking sole internal layer 2, removably improves diabetes built in cavity 4
The Chinese medicine package of patient's microcirculation.Chinese medicine package is made of the Chinese medicine composition that waterproof isolation film and sealing are filled in isolation film, in
Drug composition is powder, evenly laid out in Chinese medicine package, thickness 1.5cm, and waterproof isolation film is PE isolation films.
Wherein Chinese medicine composition is prepared by the Chinese medicine of following parts by weight：
Honeysuckle 20g, dandelion 20g, Chinese cassia tree 15g, purslane 12g, moutan bark 10g, rhizoma atractylodis 10g, Chinese violet 8g, hook
Rattan 8g, Radix Angelicae Sinensis 8g, Rhizoma Chuanxiong 10g, wild chrysanthemum 6g, coptis 6g, Cortex Eucommiae 6g, Fructus Forsythiae 2g, caulis trachelospermi 6g, root bark of Chinese wolf-berry 2g.
The preparation method of the graphene socks is as follows：
(1) preparation of sock body
Graphene oxide is prepared using Hummers methods first, 10ml mother liquors are placed in ultrasound 30min in ultrasonic wave, are obtained
To graphene oxide acid dispersion；Dispersion liquid with 50g 3,4-rthylene dioxythiophenes is mixed, is stirred evenly, centrifuges 10min,
It is dry, it weighs, obtains dried sediment 2g.2g sediments with 180g cotton fibers are mixed, are melted by screw extruder
Blending extrusion, then be granulated, sock body is then made after spinning, winding, stretching.
(2) preparation of graphene-polyethylene glycol dimethacrylate nanometer layer
Graphene oxide nanometer sheet 3g is prepared using modified Hummers methods first；Then, 50ml second two is accurately measured
Alcohol dimethylacrylate, 40ml Macrogol 6000s, 50ml dimethylformamide azodiisobutyronitriles, ultrasonic vortex 10min,
Obtain clear solution.0.14g graphene oxides nanometer sheet is added in clear solution, it is then ultrasonic in recirculated water
30min obtains finely dispersed solution.Cotton is immersed in
It in above-mentioned solution, is put into micro-wave oven and reacts 30min, then will carefully be bonded with nano coating with Medical forceps
Cotton takes out, and is 1 with volume ratio:1 methanol/water solution coating cleaning 2 times, 40 DEG C of low temperature dryings are spare.
(3) preparation of traditional Chinese powder medicine
Honeysuckle 20g, dandelion 20g, Chinese violet 8g, wild chrysanthemum 6g, coptis 6g and Fructus Forsythiae 2g are put into marmite,
Clear water is added in into marmite, medicinal material 4cm is flooded, is first boiled by fire, is boiled with soft fire 55 minutes using, the dregs of a decoction are filtered using gauze,
Liquid is obtained, it is spare；By Chinese cassia tree 15g, purslane 12g, moutan bark 10g, rhizoma atractylodis 10g, uncaria 8g, Radix Angelicae Sinensis 8g, Rhizoma Chuanxiong 10g, Du
In secondary 6g, caulis trachelospermi 6g, root bark of Chinese wolf-berry 2g input drying boxes, it is 75 DEG C to keep temperature, 25 minutes dry, obtains raw material；By gained
Raw material is put into steel mill, and holding rotating speed is 4000r/min, and crushing obtains 60 mesh medicinal powder；Gained medicinal powder is put into and has been prepared
It is uniformly mixed in good liquid, reinjects in evaporating dish, heated using moderate heat, Chinese medicine is obtained after moisture is fully evaporated
Powder.
(4) traditional Chinese powder medicine that obtains step (3) is evenly laid out on waterproof isolation film, and thickness 1.5cm takes out true
Sky, sealing, makes traditional Chinese powder medicine that cannot be moved freely in Chinese medicine package.
(5) prepared by the sock body and step (2) prepared step (1) is coated with graphene-polyethylene glycol dimethyl propylene
The stocking sole internal layer suture of olefin(e) acid ester nanometer layer, sock body top are provided with stretch cord, stocking sole outer layer and stocking sole internal layer centre shape
1 slide fastener is set close to heel part into a cavity, and in stocking sole outer layer, zipper length and stocking sole outer layer are of same size, empty
Chamber length and width are respectively greater than the length and width of Chinese medicine package, with the dismounting of convenient Chinese packet.
Embodiment 2
Refering to Fig. 2 and Fig. 3, a kind of graphene socks for improving patient with diabetic feet microcirculation, including sock body 1, socks
The material for preparing of sub- ontology 1 is formed for cotton fiber and graphene fiber mixed textile.1 top of sock body is provided with stretch cord 5,
Be provided with tightness-adjustable button 10 on stretch cord 5,1 bottom of sock body is double-layer structure, from outside to inside respectively stocking sole outer layer 3,
Stocking sole internal layer 2.3 surface of stocking sole outer layer is zigzag anti-skid structure 9.There are one draw in close 7 part of heel setting for stocking sole outer layer 3
Chain 6,6 length of slide fastener and stocking sole outer layer 3 are of same size, and stocking sole internal layer 2 is coated with graphene-polyethylene glycol dimethacrylate and receives
Rice layer (not identified in Fig. 2).A cavity 4 is formed among stocking sole outer layer 3 and stocking sole internal layer 2, is removably improved built in cavity 4
The Chinese medicine package of patient with diabetic feet microcirculation.Chinese medicine package is filled in the Chinese medicine composition in isolation film by waterproof isolation film and sealing
Composition, Chinese medicine composition is powder, evenly laid out in Chinese medicine package, thickness 2cm, and waterproof isolation film is PE isolation films.
Wherein Chinese medicine composition is prepared by the Chinese medicine of following parts by weight：
Honeysuckle 25g, dandelion 28g, Chinese cassia tree 20g, purslane 16g, moutan bark 12g, rhizoma atractylodis 12g, Chinese violet 10g,
Uncaria 12g, Radix Angelicae Sinensis 10g, Rhizoma Chuanxiong 12g, wild chrysanthemum 8g, coptis 8g, Cortex Eucommiae 8g, Fructus Forsythiae 4g, caulis trachelospermi 4g, root bark of Chinese wolf-berry 4g.
The preparation method of the graphene socks is as follows：
(1) preparation of sock body
Graphene oxide is prepared using Hummers methods first, 10ml mother liquors are placed in ultrasound 30min in ultrasonic wave, are obtained
To graphene oxide acid dispersion；Dispersion liquid with 50g 3,4-rthylene dioxythiophenes is mixed, is stirred evenly, centrifuges 10min,
It is dry, it weighs, it is dried heavy to obtain
Starch 2g.2g sediments with 180g cotton fibers are mixed, are squeezed out by screw extruder melt blending, then be granulated,
Then sock body is made after spinning, winding, stretching.
(2) preparation of graphene-polyethylene glycol dimethacrylate nanometer layer
Graphene oxide nanometer sheet 3g is prepared using modified Hummers methods first；Then, 50ml second two is accurately measured
Alcohol dimethylacrylate, 40ml Macrogol 6000s, 50ml dimethylformamide azodiisobutyronitriles, ultrasonic vortex 10min,
Obtain clear solution.0.14g graphene oxides nanometer sheet is added in clear solution, it is then ultrasonic in recirculated water
30min obtains finely dispersed solution.Cotton is immersed in above-mentioned solution, is put into micro-wave oven and reacts 30min, Ran Houyong
Medical forceps carefully take out the cotton for being bonded with nano coating, are 1 with volume ratio:1 methanol/water solution coating cleaning 2 times,
40 DEG C of low temperature dryings, it is spare.
(3) preparation of traditional Chinese powder medicine
Honeysuckle 25g, dandelion 28g, Chinese violet 10g, wild chrysanthemum 8g, coptis 8g and Fructus Forsythiae 4g are put into marmite
In, clear water is added in into marmite, medicinal material 4cm is flooded, is first boiled by fire, is boiled with soft fire 55 minutes using, medicine is filtered using gauze
Slag obtains liquid, spare；By Chinese cassia tree 20g, purslane 16g, moutan bark 12g, rhizoma atractylodis 12g, uncaria 12g, Radix Angelicae Sinensis 10g, Rhizoma Chuanxiong
In 12g, Cortex Eucommiae 8g, caulis trachelospermi 4g, root bark of Chinese wolf-berry 4g input drying boxes, it is 75 DEG C to keep temperature, 25 minutes dry, obtains raw material；
Gained raw material is put into steel mill, holding rotating speed is 3500r/min, and crushing obtains 60 mesh medicinal powder；Gained medicinal powder is put into
It is uniformly mixed in the liquid prepared, reinjects in evaporating dish, heated using moderate heat, after moisture is fully evaporated
To traditional Chinese powder medicine.
(4) traditional Chinese powder medicine that obtains step (3) is evenly laid out, and on waterproof isolation film, thickness 2cm is vacuumized,
Sealing, makes traditional Chinese powder medicine that cannot be moved freely in Chinese medicine package.
(5) prepared by the sock body and step (2) prepared step (1) is coated with graphene-polyethylene glycol dimethyl propylene
The stocking sole internal layer suture of olefin(e) acid ester nanometer layer, sock body top are provided with stretch cord, stocking sole outer layer and stocking sole internal layer centre shape
1 slide fastener is set close to heel part into a cavity, and in stocking sole outer layer, zipper length and stocking sole outer layer are of same size, empty
Chamber length and width are respectively greater than the length and width of Chinese medicine package, with the dismounting of convenient Chinese packet.
Embodiment 3
400 diabetes group foot patients are extracted, the age is 40-70 Sui, and men and women is unlimited, random respectively to choose 200 conducts
Control group and experimental group, for control group using commonly regular socks are worn 1 month, experimental group wears graphene socks of the invention 1 month,
Blood routine examination is carried out to experimental group and control group respectively before the experiments, the average value of detection data is taken, is shown in Table 1：
Table 1
| Group | RBC | HCT | MCV | HGB | MCH | MCHC | WBC |
| Experimental group | 3.4 | 36 | 67 | 100 | 22 | 240 | 3.4 |
| Control group | 3.4 | 36 | 67 | 100 | 22 | 240 | 3.4 |
Using blood routine examination is carried out after 1 month again, the average value of detection data is taken, is shown in Table 2：
Table 2
| Group | RBC | HCT | MCV | HGB | MCH | MCHC | WBC |
| Experimental group | 5.5 | 48 | 95 | 150 | 40 | 360 | 8 |
| Control group | 3.4 | 36 | 67 | 100 | 22 | 240 | 3.4 |
Significantly changed the experimental results showed that wearing experimental group foot microcirculation of the graphene socks of the present invention after 1 month
Kind, blood routine data reach normal value, and the control group for wearing regular socks cannot promote blood circulation, and blood routine data are relatively low.
In addition, the symptom of experimental group patients feet numbness disappears, illustrate the clinic of the graphene socks treatment diabetes of the present invention
Significant effect.
The present invention is the technical solution by being obtained after graphene socks of the prior art are improved, and is improving diabetes
In terms of sufficient patient's microcirculation, clinical effectiveness is notable, can easily be adhered to, easily by patient with other diseases such as auxiliary treatment liver kidneys
Receive, have no adverse reaction.Graphene socks easily wash, can Reusability, economize on resources.
Certainly, it is limitation of the present invention that above description, which is not, and the present invention is also not limited to the example above, the art
Those of ordinary skill, any variation, addition or the replacement made in the essential scope of the present invention should also belong to the present invention's
Protection domain.
Claims (10)
1. a kind of graphene socks for improving patient with diabetic feet microcirculation, which is characterized in that described including sock body (1)
Stretch cord (5) is provided at the top of sock body (1), sock body (1) bottom is double-deck, from outside to inside respectively stocking sole outer layer
(3), stocking sole internal layer (2), there are one slide fastener (6), the slide fasteners (6) in the setting of close heel (7) part for the stocking sole outer layer (3)
Length and stocking sole outer layer (3) are of same size, and the stocking sole internal layer (2) is coated with graphene-polyethylene glycol dimethacrylate and receives
Rice layer, forms a cavity (4) among the stocking sole outer layer (3) and stocking sole internal layer (2), built in the cavity (4) removably
Improve the Chinese medicine package of patient with diabetic feet microcirculation, the Chinese medicine package is filled in by waterproof isolation film and sealing in the isolation film
Chinese medicine composition composition, the Chinese medicine composition be powder, the Chinese medicine composition by following parts by weight Chinese medicine prepare and
Into：
20~30 parts of honeysuckle, 20~30 parts of dandelion, 15~25 parts of Chinese cassia tree, 12~20 parts of purslane, 10~15 parts of moutan bark,
10~15 parts of rhizoma atractylodis, 8~15 parts of Chinese violet, 8~15 parts of uncaria, 8~15 parts of Radix Angelicae Sinensis, 10~15 parts of Rhizoma Chuanxiong, wild chrysanthemum 6~10
Part, 6~10 parts of the coptis, 6~10 parts of Cortex Eucommiae, 2~4 parts of Fructus Forsythiae, 6~12 parts of caulis trachelospermi, 2~4 parts of the root bark of Chinese wolf-berry.
2. improve the graphene socks of patient with diabetic feet microcirculation according to claim 1, which is characterized in that the socks
Ontology (1) is formed by cotton fiber and graphene fiber mixed textile.
3. improve the graphene socks of patient with diabetic feet microcirculation according to claim 1, which is characterized in that the Chinese medicine
Composition is prepared by the Chinese medicine of following parts by weight：
25 parts of honeysuckle, 28 parts of dandelion, 20 parts of Chinese cassia tree, 16 parts of purslane, 12 parts of moutan bark, 12 parts of rhizoma atractylodis, Chinese violet 10
Part, 12 parts of uncaria, 10 parts of Radix Angelicae Sinensis, 12 parts of Rhizoma Chuanxiong, 8 parts of wild chrysanthemum, 8 parts of the coptis, 8 parts of Cortex Eucommiae, 4 parts of Fructus Forsythiae, 4 parts of caulis trachelospermi,
4 parts of bone skin.
4. according to any one of claims 1 to 3 graphene socks for improving patient with diabetic feet microcirculation, feature exists
In the Chinese medicine composition is evenly laid out in Chinese medicine package.
5. improve the graphene socks of patient with diabetic feet microcirculation according to claim 4, which is characterized in that the Chinese medicine
Composition thickness is 1~2cm.
6. improve the graphene socks of patient with diabetic feet microcirculation according to claim 5, which is characterized in that the Chinese medicine
Composition thickness is 1.5cm.
7. improve the graphene socks of patient with diabetic feet microcirculation according to claim 1, which is characterized in that the waterproof
Isolation film is PE isolation films.
It is 8. special according to any one of claims 1 to 3,5~7 the graphene socks for improving patient with diabetic feet microcirculation
Sign is that stocking sole outer layer (3) surface is zigzag anti-skid structure (9).
9. improve the graphene socks of patient with diabetic feet microcirculation according to claim 8, which is characterized in that the elastic force
Tightness-adjustable button (10) is provided on rope (5).
10. improve the graphene socks of patient with diabetic feet microcirculation according to claim 8, which is characterized in that the bullet
Power rope (5) circular array (8) is set.
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Cited By (1)
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