CN108159203A - A kind of preparation method for the spray that scald is promoted to repair - Google Patents
A kind of preparation method for the spray that scald is promoted to repair Download PDFInfo
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Abstract
The present invention relates to technical field of traditional Chinese medicines more particularly to a kind of preparation methods for the spray that scald is promoted to repair.The present invention prepares spray using chitosan; since chitosan has film forming, antibiotic property; one layer of liquid film sticked can be formed by being sprayed on skin wound; resist extraneous bacterium infection; the protection surface of a wound simultaneously forms wet environment, promotes wound healing; chitosan also has adsorptivity simultaneously, so as to be maintained active ingredient.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines more particularly to a kind of preparation methods for the spray that scald is promoted to repair.
Background technology
Burn be tissue by the variation that high temp objects or heat radiation injure and occur, traumatogenic reason includes
Flame, hot iron, boiling oil, boiling water, soup, electric arc and chemical substance etc. cause.Its degree injured, in terms of pathologic angle
It is divided into four degree, first degree：It is congested due to angioparalysis.Second degree：Form the burn blister full of serum.Third degree：It organizes bad
Extremely.It is fourth：The charing of tissue；It is divided into three degree for clinical dialectical angle, i.e.,：Rubefaction, pain or apparent tenderness,
There are diffusate or oedema, but be I degree without blister.There is blister in skin, and blister bottom takes on a red color or white, is filled with clear
Clear, sticky liquid is touched a tender spot sensitive, and it is II degree that when compressing, which bleaches,.Skin surface whitens, softens, diabrosis or in black,
Charing, hide-like are all III degree.It should be noted that when just burning, the typically no pain sensation of III degree burn areas, because of skin
Nerve endings be destroyed, but tissue downright bad after a few days will appear erosion, so burnt degree is often required to through in a few days, ability
Depth II degree is distinguished to burn with III degree.
Burn and scald is a kind of common disease, annoyings many patients for a long time.Burn and scald is the thermal damage of skin, heat
Poison is suffers from, and therefore, how to protect the surface of a wound, reduction exudation, prevention infection is the main problem for needing to solve.And treat burn and scald
Principle is exactly clearing heat and detoxicating, cooling and activating blood, clearing damp and promoting diuresis, supplementing qi and nourishing yin.
The types of drugs for the treatment of burn and scald is more at present, is basically divided into Chinese medicine and Western medicine, is risen by burnt degree
Bubble, skin break, fester after treatment passive not in time, bring great pain to patient, economic loss and worry caused to family
Fatigue or even the huge psychological pressure that the mistake of maimed and appearance can be caused beautiful；In addition, the raw material of Western medicine is mostly chemical substance, effect
It is single, and or stimulation can be generated to application on human skin, some long-time services have dependence or have side effect.Traditional Chinese medicine controls burn outside
Aspect has rich experience, and the theoretical level for controlling burn outside traditional Chinese medicine in recent years is continuously improved, and clinical experience is enriched constantly, clinical excellent
Gesture is more and more apparent.
At present, the drug for treating burn and scald is more, jingwanhong soft plaster, rhubarb tincture, yellow glue pyrimidine silver etc., these drugs are scalded to treating
Wound has the effect of certain, but there is also some shortcomings and problem.First, healing time is long, wants multiple medication, repeatedly smears, and
And dosage is big, medical expense is high；Second is that the surface of a wound easily infects, there are scars after slow, healing of forming a scab.
In summary, the Chinese and Western medicine of the treatment burn and scald of the prior art and the formula of Chinese materia medica preparation number for the treatment of burn and scald skin lesion
I is unequal to counting, and has the following disadvantages mostly：Analgesic effect is poor, and patient suffering is larger during dressing, medicine antibacterial energy force difference, and the surface of a wound is easy
There are scars slowly, after healing for infection, incrustation, longer the time required to curing, and basic need cooperation skin grafting and amputation ability
Reach healing.
Therefore, we are a kind of for scalding the composition repaired it is necessary to preparing again, and existing city is made up with this
On field for scalding the defects of drug repaired has, push the development of China's pharmaceuticals industry with this, and this, also will be
One very significant thing.
Invention content
The technical problems to be solved by the invention：For there are many current topical agents for treating burn and scald, but its effect
It is irregular, and some easily stay scar, it is impossible to reach satisfied healing effect, a kind of system for the spray that scald is promoted to repair is provided
Preparation Method.
In order to solve the above technical problems, the present invention is using technical solution as described below：
A kind of preparation method for the spray that scald is promoted to repair, the preparation method include the following steps：
（1）Jellyfish is cut into small pieces, then is freeze-dried, obtains dried object, in mass ratio 1：：20~30：40 ~ 50, by drying
Object, sodium carbonate liquor, edta solution are mixed, and stirring 20 ~ for 24 hours, add 30 ~ 40 times of dried object quality
Acetic acid solution is mixed, and is extracted at 60 ~ 70 DEG C of temperature, obtains extracting solution, and extracting solution quality 1 ~ 2% is added in into extracting solution
Papain, hydrolyzed at 50 ~ 55 DEG C of temperature, 8 ~ 10 min of water-bath enzyme deactivation at 90 ~ 100 DEG C of temperature, after cooling, from
The heart takes supernatant；
（2）Sea-buckthorn is crushed, is sieved, obtains sieving, in mass ratio 1：5 ~ 6, sieving, n-hexane are mixed, soaked
Bubble, extraction, obtains extracting solution a, counts in parts by weight, take 10 ~ 15 portions of supernatants, 2 ~ 3 parts of extracting solution a, 0.2 ~ 0.3 part of composite emulsifying
Agent, 0.05 ~ 0.07 part of xanthans, 0.05 ~ 0.07 part of sodium carboxymethylcellulose, by supernatant, extracting solution a, compound emulsifying agent, Huang
Virgin rubber, sodium carboxymethylcellulose are mixed, then the emulsifying at 60 ~ 65 DEG C of temperature, obtain mixed liquor；
（3）It counts in parts by weight, takes 40 ~ 50 parts of ethyl alcohol, 30 ~ 40 parts of water, 7 ~ 8 portions of arbor-vitaes, 5 ~ 6 parts of rheum officinales, 2 ~ 3 parts of sansevieria trifasciatas,
Arbor-vitae, rheum officinale, sansevieria trifasciata are eluted with water, crushed, after water is added to be sufficiently mixed, adds ethyl alcohol, heating and refluxing extraction filters,
Filtrate is collected, and squeezes the dregs of a decoction, pressed liquor merges with filtrate, collects gained liquid, and be sieved, filters 2 times, collects filtrate a, press
Mass ratio 10 ~ 15：2 ~ 3, mixed liquor, filtrate a are uniformly mixed, obtain mixed liquor a；
（4）In mass ratio 1：0.5：200：100, chitosan, lactic acid, ethyl alcohol, purified water are mixed, and stirs evenly, and
It is fitted into spray bottle, then in 80 ~ 85 DEG C of freeze-day with constant temperature 0.8 ~ 1h of box sterilization of temperature together with the mixed liquor a for purifying 1 ~ 2 times of water quality,
20 ~ 24 h are placed at room temperature for, sterilize 2 ~ 3 times repeatedly to get the spray that scald is promoted to repair.
The step（2）Middle compound emulsifying agent is in mass ratio 1：1, by monoglyceride, sucrose ester be uniformly mixed to get
Compound emulsifying agent.
Compared with other methods, advantageous effects are the present invention：
（1）A kind of drug that the present invention is extracted from sea-buckthorn seed is oily, the vitamin C of rich content in Seabuckthorn Oil,
By participating in the hydroxylation of proline and lysine, increase collagenous fibres synthesis, so as to promote local connective tissue
Reparation, and vitamin C can increase the density of capillary and mitigate its permeability and brittleness, mitigate local inflammation, exudation subtracts
It is few, at the same with a kind of substance for the scar that can dispel is extracted from jellyfish, can directly penetrate into skin bottom, and with the parent of surrounding tissue
It is good with property, can helper cell be manufactured into collagen, promote Skin Cell normal growth, meanwhile, itself also have anti-inflammatory and
The effect of skin is updated, the two effect superposition so as to further improve the ability of the skin repair of spray, while wherein also contains
There is superoxide dismutase that can dispose the free radical in human body, cleaning and environment purification pollution, reach skin whitening, delay
Skin aging attacks effect, even if so as to be sprayed on outside wound, also has certain benefit to skin, is additionally added extracts of Chinese herbal medicine,
Also have swelling and pain relieving, saprophytic removing effect in one side herbal raw material, it is another so as to further strengthen the effect of spray
Contain volatile oil in aspect medicinal herb components, have good mechanism to water-soluble and fat-soluble medicine, it is stingless to skin
Swash property, there is the double action for promoting to blend treatment, so as to promote active ingredient Transdermal absorption, improve wound healing rate.
（2）The present invention prepares spray using chitosan, since chitosan has film forming, antibiotic property, is sprayed on
Skin wound can form one layer and stick glutinous liquid film, resist extraneous bacterium infection, protect the surface of a wound and form wet environment, promote wound
Healing, while chitosan also has adsorptivity, so as to be maintained active ingredient.
Specific embodiment
Purified water is purchased from Wuxi Ke Lei Water Management Equipment Ltd..
Compound emulsifying agent is in mass ratio 1：1, monoglyceride, sucrose ester are uniformly mixed to get compound emulsifying agent.
A kind of preparation method for the spray that scald is promoted to repair, the preparation method include the following steps：
（1）Jellyfish is cut into small pieces, then is freeze-dried, obtains dried object, in mass ratio 1：：20~30：40 ~ 50, by drying
Object, 0.5 mol/L sodium carbonate liquors, 0.3 mol/L edta solutions are mixed, and are stirred with 200 ~ 300r/min
20 ~ for 24 hours, the 0.5 mol/L acetic acid solutions for adding 30 ~ 40 times of dried object quality are mixed, and are carried at 60 ~ 70 DEG C of temperature
Take 20 ~ for 24 hours, extracting solution is obtained, the papain of extracting solution quality 1 ~ 2% is added in into extracting solution, in 50 ~ 55 DEG C of temperature, pH is
2 ~ 3h is hydrolyzed under conditions of 6 ~ 7,8 ~ 10 min of water-bath enzyme deactivation at 90 ~ 100 DEG C of temperature, after cooling, with 4000 ~ 4500r/
Min centrifuges 10 ~ 15 min, takes supernatant；
（2）Sea-buckthorn is crushed, 40 ~ 50 mesh sieve is crossed, obtains sieving, in mass ratio 1：5 ~ 6, by sieving,
N-hexane is mixed, and is impregnated 1 ~ 2h, then 5 ~ 6h is extracted at 75 ~ 80 DEG C of temperature, is obtained extracting solution a, count in parts by weight,
Take 10 ~ 15 portions of supernatants, 2 ~ 3 parts of extracting solution a, 0.2 ~ 0.3 part of compound emulsifying agent, 0.05 ~ 0.07 part of xanthans, 0.05 ~ 0.07
Part sodium carboxymethylcellulose, supernatant, extracting solution a, compound emulsifying agent, xanthans, sodium carboxymethylcellulose are mixed, then
The emulsifying at 60 ~ 65 DEG C of temperature, obtains mixed liquor；
（3）It counts in parts by weight, takes 40 ~ 50 parts of ethyl alcohol, 30 ~ 40 parts of water, 7 ~ 8 portions of arbor-vitaes, 5 ~ 6 parts of rheum officinales, 2 ~ 3 parts of sansevieria trifasciatas,
Arbor-vitae, rheum officinale, sansevieria trifasciata are eluted with water, crushes, after water is added to be sufficiently mixed, adds ethyl alcohol, is heated at 70 ~ 80 DEG C of temperature
1 ~ 2h of refluxing extraction, filtering collect filtrate, and squeeze the dregs of a decoction, and pressed liquor merges with filtrate, collect obtained by liquid, and 300 ~
350 mesh sieve, filter 2 times, collect filtrate a, in mass ratio 10 ~ 15：2 ~ 3, mixed liquor, filtrate a are uniformly mixed, must be mixed
Liquid a；
（4）In mass ratio 1：0.5：200：100, chitosan, lactic acid, ethyl alcohol, purified water are mixed, and with 200 ~ 300r/
Min is stirred evenly, and is fitted into spray bottle, then in 80 ~ 85 DEG C of constant temperature of temperature together with the mixed liquor a for purifying 1 ~ 2 times of water quality
0.8 ~ 1h of dry box sterilization, is placed at room temperature for 20 ~ 24 h, sterilizes 2 ~ 3 times repeatedly to get the spray that scald is promoted to repair.
Embodiment 1
Purified water is purchased from Wuxi Ke Lei Water Management Equipment Ltd..
Compound emulsifying agent is in mass ratio 1：1, monoglyceride, sucrose ester are uniformly mixed to get compound emulsifying agent.
A kind of preparation method for the spray that scald is promoted to repair, the preparation method include the following steps：
（1）Jellyfish is cut into small pieces, then is freeze-dried, obtains dried object, in mass ratio 1：：20：40, by dried object, 0.5
Mol/L sodium carbonate liquors, 0.3 mol/L edta solutions are mixed, and stir 20h with 200r/min, are added
0.5 mol/L acetic acid solutions of 30 times of dried object quality are mixed, and extract 20h under temperature 60 C, obtain extracting solution, to carrying
The papain that extracting solution quality 1% is added in liquid is taken, in temperature 50 C, pH hydrolyzes 2h under conditions of being 6, in 90 DEG C of temperature
Lower water-bath enzyme deactivation 8min after cooling, centrifuges 10 min with 4000r/min, takes supernatant；
（2）Sea-buckthorn is crushed, 40 mesh sieve is crossed, obtains sieving, in mass ratio 1：5, by sieving,
N-hexane is mixed, and is impregnated 1h, then extract 5h at 75 DEG C of temperature, is obtained extracting solution a, count in parts by weight, take 10 parts
Supernatant, 2 parts of extracting solution a, 0.2 part of compound emulsifying agent, 0.05 part of xanthans, 0.05 part of sodium carboxymethylcellulose, by supernatant,
Extracting solution a, compound emulsifying agent, xanthans, sodium carboxymethylcellulose are mixed, then the emulsifying under temperature 60 C, are obtained mixed
Close liquid；
（3）Count in parts by weight, take 40 parts of ethyl alcohol, 30 parts of water, 7 portions of arbor-vitaes, 5 parts of rheum officinales, 2 parts of sansevieria trifasciatas, by arbor-vitae, rheum officinale,
Sansevieria trifasciata is eluted with water, and crushes, after water is added to be sufficiently mixed, adds ethyl alcohol, heating and refluxing extraction 1h, mistake under temperature 70 C
Filter collects filtrate, and squeezes the dregs of a decoction, and pressed liquor merges with filtrate, collects gained liquid, and crosses 300 mesh sieve, filters 2 times, collects
Filtrate a, in mass ratio 10：2, mixed liquor, filtrate a are uniformly mixed, obtain mixed liquor a；
（4）In mass ratio 1：0.5：200：100, chitosan, lactic acid, ethyl alcohol, purified water are mixed, and is stirred with 200r/min
It mixes uniformly, and is fitted into spray bottle, then in 80 DEG C of freeze-day with constant temperature box sterilizations of temperature together with the mixed liquor a for purifying 1 times of water quality
0.8h is placed at room temperature for 20h, sterilizes 2 times repeatedly to get the spray that scald is promoted to repair.
Embodiment 2
Purified water is purchased from Wuxi Ke Lei Water Management Equipment Ltd..
Compound emulsifying agent is in mass ratio 1：1, monoglyceride, sucrose ester are uniformly mixed to get compound emulsifying agent.
A kind of preparation method for the spray that scald is promoted to repair, the preparation method include the following steps：
（1）Jellyfish is cut into small pieces, then is freeze-dried, obtains dried object, in mass ratio 1：：25：45, by dried object, 0.5
Mol/L sodium carbonate liquors, 0.3 mol/L edta solutions are mixed, and stir 22h with 250r/min, are added
0.5 mol/L acetic acid solutions of 35 times of dried object quality are mixed, and extract 22h at 65 DEG C of temperature, obtain extracting solution, to carrying
The papain that extracting solution quality 1% is added in liquid is taken, in 52 DEG C of temperature, pH hydrolyzes 2h under conditions of being 6, in 95 DEG C of temperature
Lower water-bath enzyme deactivation 9min after cooling, centrifuges 12min with 4300r/min, takes supernatant；
（2）Sea-buckthorn is crushed, 45 mesh sieve is crossed, obtains sieving, in mass ratio 1：5, by sieving,
N-hexane is mixed, and is impregnated 1h, then extract 5h at 77 DEG C of temperature, is obtained extracting solution a, count in parts by weight, take 12 parts
Supernatant, 2 parts of extracting solution a, 0.2 part of compound emulsifying agent, 0.06 part of xanthans, 0.06 part of sodium carboxymethylcellulose, by supernatant,
Extracting solution a, compound emulsifying agent, xanthans, sodium carboxymethylcellulose are mixed, then the emulsifying at 63 DEG C of temperature, are obtained mixed
Close liquid；
（3）Count in parts by weight, take 45 parts of ethyl alcohol, 35 parts of water, 7 portions of arbor-vitaes, 5 parts of rheum officinales, 2 parts of sansevieria trifasciatas, by arbor-vitae, rheum officinale,
Sansevieria trifasciata is eluted with water, and crushes, after water is added to be sufficiently mixed, adds ethyl alcohol, the heating and refluxing extraction 1h at 75 DEG C of temperature, mistake
Filter collects filtrate, and squeezes the dregs of a decoction, and pressed liquor merges with filtrate, collects gained liquid, and crosses 320 mesh sieve, filters 2 times, collects
Filtrate a, in mass ratio 12：2, mixed liquor, filtrate a are uniformly mixed, obtain mixed liquor a；
（4）In mass ratio 1：0.5：200：100, chitosan, lactic acid, ethyl alcohol, purified water are mixed, and is stirred with 250r/min
It mixes uniformly, and is fitted into spray bottle, then in 82 DEG C of freeze-day with constant temperature box sterilizations of temperature together with the mixed liquor a for purifying 1 times of water quality
0.9h is placed at room temperature for 22h, sterilizes 2 times repeatedly to get the spray that scald is promoted to repair.
Embodiment 3
Purified water is purchased from Wuxi Ke Lei Water Management Equipment Ltd..
Compound emulsifying agent is in mass ratio 1：1, monoglyceride, sucrose ester are uniformly mixed to get compound emulsifying agent.
A kind of preparation method for the spray that scald is promoted to repair, the preparation method include the following steps：
（1）Jellyfish is cut into small pieces, then is freeze-dried, obtains dried object, in mass ratio 1：：30：50, by dried object, 0.5
Mol/L sodium carbonate liquors, 0.3 mol/L edta solutions are mixed, and with 300r/min stirrings for 24 hours, are added
0.5 mol/L acetic acid solutions of 40 times of dried object quality are mixed, and extracted for 24 hours under temperature 70 C, obtain extracting solution, to carrying
The papain that extracting solution quality 1 ~ 2% is added in liquid is taken, in 55 DEG C of temperature, pH hydrolyzes 3h under conditions of being 7, in temperature 100
10 min of water-bath enzyme deactivation at DEG C after cooling, centrifuges 15 min with 4500r/min, takes supernatant；
（2）Sea-buckthorn is crushed, 50 mesh sieve is crossed, obtains sieving, in mass ratio 1：6, by sieving,
N-hexane is mixed, and is impregnated 2h, then extract 6h at 80 DEG C of temperature, is obtained extracting solution a, count in parts by weight, take 15 parts
Supernatant, 3 parts of extracting solution a, 0.3 part of compound emulsifying agent, 0.07 part of xanthans, 0.07 part of sodium carboxymethylcellulose, by supernatant,
Extracting solution a, compound emulsifying agent, xanthans, sodium carboxymethylcellulose are mixed, then the emulsifying at 65 DEG C of temperature, are obtained mixed
Close liquid；
（3）Count in parts by weight, take 50 parts of ethyl alcohol, 40 parts of water, 8 portions of arbor-vitaes, 6 parts of rheum officinales, 3 parts of sansevieria trifasciatas, by arbor-vitae, rheum officinale,
Sansevieria trifasciata is eluted with water, and crushes, after water is added to be sufficiently mixed, adds ethyl alcohol, the heating and refluxing extraction 2h at 80 DEG C of temperature, mistake
Filter collects filtrate, and squeezes the dregs of a decoction, and pressed liquor merges with filtrate, collects gained liquid, and crosses 350 mesh sieve, filters 2 times, collects
Filtrate a, in mass ratio 15：3, mixed liquor, filtrate a are uniformly mixed, obtain mixed liquor a；
（4）In mass ratio 1：0.5：200：100, chitosan, lactic acid, ethyl alcohol, purified water are mixed, and is stirred with 300r/min
It mixes uniformly, and is fitted into spray bottle, then in 85 DEG C of freeze-day with constant temperature box sterilizations of temperature together with the mixed liquor a for purifying 2 times of water quality
1h is placed at room temperature for 24 h, sterilizes 3 times repeatedly to get the spray that scald is promoted to repair.
Comparative example：The scald of Guangzhou bio tech ltd production repairs medicament
Method：400 burned patients are chosen as experimenter, 4 groups are classified as, respectively using prepared by embodiment and comparative example
Scald repair medicament, it is daily to continue 40 days using twice, after the test, record the use feedback of tester.
Scald repairs the specific detection case of medicament such as table 1
Table 1
Note：Effective percentage adds effective statistics to fully recover.
Safety testing：It chooses embodiment and repairs medicament with the scald that comparative example is produced, choose four matter yellowish-brown adult
Cavy goes to hair-fields in its back both sides shaving into several.Scald is repaired into medicament daily and is coated on hair-fields, is examined after experiment
Survey its safety.
Scald repairs pharmacy security detection case such as table 2
Table 2
From the foregoing, it will be observed that the scald reparation that the present invention is produced can effectively treat scald affected part, and application method with spray
It is simple to operation, be not easy to stay scar, be a kind of safety and the efficient medicament for repairing scald, security and stability is high, be worthy to be popularized and
It uses.
Claims (2)
1. a kind of preparation method for the spray that scald is promoted to repair, which is characterized in that the preparation method includes the following steps：
（1）Jellyfish is cut into small pieces, then is freeze-dried, obtains dried object, in mass ratio 1：：20~30：40 ~ 50, by drying
Object, sodium carbonate liquor, edta solution are mixed, and stirring 20 ~ for 24 hours, add 30 ~ 40 times of dried object quality
Acetic acid solution is mixed, and is extracted at 60 ~ 70 DEG C of temperature, obtains extracting solution, and extracting solution quality 1 ~ 2% is added in into extracting solution
Papain, hydrolyzed at 50 ~ 55 DEG C of temperature, 8 ~ 10 min of water-bath enzyme deactivation at 90 ~ 100 DEG C of temperature, after cooling, from
The heart takes supernatant；
（2）Sea-buckthorn is crushed, is sieved, obtains sieving, in mass ratio 1：5 ~ 6, sieving, n-hexane are mixed, soaked
Bubble, extraction, obtains extracting solution a, counts in parts by weight, take 10 ~ 15 portions of supernatants, 2 ~ 3 parts of extracting solution a, 0.2 ~ 0.3 part of composite emulsifying
Agent, 0.05 ~ 0.07 part of xanthans, 0.05 ~ 0.07 part of sodium carboxymethylcellulose, by supernatant, extracting solution a, compound emulsifying agent, Huang
Virgin rubber, sodium carboxymethylcellulose are mixed, then the emulsifying at 60 ~ 65 DEG C of temperature, obtain mixed liquor；
（3）It counts in parts by weight, takes 40 ~ 50 parts of ethyl alcohol, 30 ~ 40 parts of water, 7 ~ 8 portions of arbor-vitaes, 5 ~ 6 parts of rheum officinales, 2 ~ 3 parts of sansevieria trifasciatas,
Arbor-vitae, rheum officinale, sansevieria trifasciata are eluted with water, crushed, after water is added to be sufficiently mixed, adds ethyl alcohol, heating and refluxing extraction filters,
Filtrate is collected, and squeezes the dregs of a decoction, pressed liquor merges with filtrate, collects gained liquid, and be sieved, filters 2 times, collects filtrate a, press
Mass ratio 10 ~ 15：2 ~ 3, mixed liquor, filtrate a are uniformly mixed, obtain mixed liquor a；
（4）In mass ratio 1：0.5：200：100, chitosan, lactic acid, ethyl alcohol, purified water are mixed, and stirs evenly, and
It is fitted into spray bottle, then in 80 ~ 85 DEG C of freeze-day with constant temperature 0.8 ~ 1h of box sterilization of temperature together with the mixed liquor a for purifying 1 ~ 2 times of water quality,
20 ~ 24 h are placed at room temperature for, sterilize 2 ~ 3 times repeatedly to get the spray that scald is promoted to repair.
2. the preparation method of spray that scald is promoted to repair according to claim 1, which is characterized in that the step（2）
Middle compound emulsifying agent is in mass ratio 1：1, monoglyceride, sucrose ester are uniformly mixed to get compound emulsifying agent.
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Application publication date: 20180615 |